| C049325 | 1,2-dithiol-3-thione | "1,2-dithiol-3-thione results in decreased expression of HPRT1 mRNA" | 19162173 |
| C090203 | 1,2-epoxy-3,4-dihydroxy-1,2,3,4-tetrahydrobenzo(c)phenanthrene | "1,2-epoxy-3,4-dihydroxy-1,2,3,4-tetrahydrobenzo(c)phenanthrene results in increased mutagenesis of HPRT1 gene" | 8706010 |
| C022146 | 1-(2-hydroxyethyl)-1-nitrosourea | 1-(2-hydroxyethyl)-1-nitrosourea results in increased mutagenesis of HPRT1 gene | 7728755 |
| C037414 | 1,3,6-trinitropyrene | "1,3,6-trinitropyrene results in increased mutagenesis of HPRT1 gene" | 6681862 |
| C031763 | 1,3-butadiene | "1,3-butadiene metabolite results in increased mutagenesis of HPRT1 gene" | 20853577 |
| C031763 | 1,3-butadiene | "1,3-butadiene metabolite results in increased mutagenesis of HPRT1 gene" | 20017413 |
| C031763 | 1,3-butadiene | "1,3-butadiene results in increased mutagenesis of HPRT1 gene" | 20017413|2097411 |
| C031763 | 1,3-butadiene | "1,3-butadiene metabolite results in increased mutagenesis of HPRT1 gene" | 20017413 |
| C031763 | 1,3-butadiene | "1,3-butadiene results in increased mutagenesis of HPRT1 gene" | 20974116 |
| C033309 | 1,6-dinitropyrene | "1,6-dinitropyrene results in increased mutagenesis of HPRT1 gene" | 6681862 |
| C033310 | 1,8-dinitropyrene | "1,8-dinitropyrene results in increased mutagenesis of HPRT1 gene" | 2385180|6681862 |
| C033020 | 1-aminobenzotriazole | 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] | 25243916 |
| C065833 | 1-hydroxymethylpyrene | Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene] | 25243916 |
| C065833 | 1-hydroxymethylpyrene | [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene | 25243916 |
| C064701 | 1-methoxy-3-indolylmethylglucosinolate | 1-methoxy-3-indolylmethylglucosinolate metabolite results in increased mutagenesis of HPRT1 gene | 20846518 |
| C053035 | 1-methylpyrene | 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] | 25243916 |
| C053035 | 1-methylpyrene | Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] | 25243916 |
| C053035 | 1-methylpyrene | [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene | 25243916 |
| C032668 | 1-nitropyrene | 1-nitropyrene results in increased mutagenesis of HPRT1 gene | 10727902 |
| C032668 | 1-nitropyrene | CYP1A2 affects the reaction [1-nitropyrene results in increased mutagenesis of HPRT1 gene] | 10727902 |
| C057066 | 1-nitropyrene-4,5-oxide | "1-nitropyrene-4,5-oxide results in increased mutagenesis of HPRT1 gene" | 15750348 |
| C057067 | 1-nitropyrene-9,10-oxide | "1-nitropyrene-9,10-oxide results in increased mutagenesis of HPRT1 gene" | 15750348 |
| C044707 | 1-nitrosopyrene | 1-nitrosopyrene results in increased mutagenesis of HPRT1 gene | 1541256|1586993| |
| C044707 | 1-nitrosopyrene | 1-nitrosopyrene results in increased mutagenesis of HPRT1 gene | 8033153 |
| C111118 | 2',3,3',4',5-pentachloro-4-hydroxybiphenyl | "2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of HPRT1 mRNA" | 19114083 |
| C029497 | 2,3-bis(3'-hydroxybenzyl)butyrolactone | "[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HPRT1 mRNA" | 19167446 |
| C541132 | 2,4,4',5-tetrachlorobiphenyl | "[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,4,4',5-tetrachlorobiphenyl] which results in increased mutagenesis of HPRT1 gene" | 27913846 |
| C009407 | 2,5,2',5'-tetrachlorobiphenyl | "[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,5,2',5'-tetrachlorobiphenyl] which results in increased mutagenesis of HPRT1 gene" | 27913846 |
| C502239 | 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct | "[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct] which results in increased mutagenesis of HPRT1 gene" | 7728948 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1" | 9202738 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with CYP1A2 protein] results in increased mutagenesis of HPRT1 gene" | 8625468 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct] which results in increased mutagenesis of HPRT1 gene" | 7728948 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased mutagenesis of HPRT1 gene" | 7728948 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene" | 10728688|1098730 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 intron" | 7728948 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 intron] which affects the splicing of HPRT1 mRNA" | 7728948|7728948 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene" | 11289141|1246714 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "Ascorbic Acid inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]" | 12467141 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "beta Carotene inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]" | 12467141 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "Vitamin E inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]" | 12467141 |
| C036989 | 2-amino-3,4-dimethylimidazo(4,5-f)quinoline | "2-amino-3,4-dimethylimidazo(4,5-f)quinoline results in increased mutagenesis of HPRT1 gene" | 12467141 |
| C036990 | 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline | "2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased mutagenesis of HPRT1 gene" | 12467141 |
| C029216 | 2-amino-3-methylimidazo(4,5-f)quinoline | "2-amino-3-methylimidazo(4,5-f)quinoline results in increased mutagenesis of HPRT1 gene" | 12467141 |
| C017822 | 2-amino-9H-pyrido(2,3-b)indole | "2-amino-9H-pyrido(2,3-b)indole binds to and results in increased mutagenesis of HPRT1 gene" | 19243127 |
| C017822 | 2-amino-9H-pyrido(2,3-b)indole | "[CYP1A2 protein co-treated with NAT2 gene polymorphism] promotes the reaction [2-amino-9H-pyrido(2,3-b)indole binds to and results in increased mutagenesis of HPRT1 gene]" | 19243127 |
| C051268 | 2-hydroxychavicol | [2-hydroxychavicol co-treated with Benzo(a)pyrene] results in increased mutagenesis of HPRT1 gene | 15331132 |
| C080053 | 3,4-epoxybutane-1,2-diol | "3,4-epoxybutane-1,2-diol results in increased mutagenesis of HPRT1 exon" | 12521305 |
| C080053 | 3,4-epoxybutane-1,2-diol | "3,4-epoxybutane-1,2-diol results in increased mutagenesis of HPRT1 gene SNP" | 12521305 |
| C080053 | 3,4-epoxybutane-1,2-diol | "3,4-epoxybutane-1,2-diol metabolite results in increased mutagenesis of HPRT1 gene" | 20853577 |
| C019133 | 3-amino-1-methyl-5H-pyrido(4,3-b)indole | "3-amino-1-methyl-5H-pyrido(4,3-b)indole results in increased mutagenesis of HPRT1 gene" | 2335011 |
| C054121 | 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone | 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone results in increased mutagenesis of HPRT1 gene | 7519319|7607182 |
| C054121 | 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone | 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone results in increased mutagenesis of HPRT1 gene | 17993254 |
| C117220 | 3-nitrobenzanthrone | [NAT2 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene | 17483118 |
| C117220 | 3-nitrobenzanthrone | [SULT1A1 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene | 17483118 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HPRT1 mRNA" | 27188386 |
| C081510 | 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone | 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of HPRT1 gene | 19601657 |
| C081510 | 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone | ERCC2 protein affects the susceptibility to [4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of HPRT1 gene] | 19601657 |
| C081510 | 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone | XRCC1 protein affects the susceptibility to [4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of HPRT1 gene] | 19601657 |
| C026729 | 4-aminophenol | 4-aminophenol results in increased mutagenesis of HPRT1 gene | 7556113 |
| C006757 | 4-biphenylamine | [NAT1 polymorphism results in increased susceptibility to 4-biphenylamine] which results in increased mutagenesis of HPRT1 gene | 22114069 |
| C006983 | 4-chlorobiphenyl | 4-chlorobiphenyl metabolite results in increased mutagenesis of HPRT1 gene | 17686921 |
| C027576 | 4-hydroxy-2-nonenal | 4-hydroxy-2-nonenal results in increased expression of HPRT1 mRNA | 19191707 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of HPRT1 gene | 15613823 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Dibutyl Phthalate promotes the reaction [[Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene] | 15613823 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | [Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene | 15613823 |
| C009785 | 4-pentenoic acid | 4-pentenoic acid results in increased expression of HPRT1 mRNA | 12883083 |
| C029370 | 4-toluidine | 4-toluidine results in increased expression of HPRT1 mRNA | 27638505 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HPRT1 mRNA" | 27188386 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of HPRT1 mRNA | 12883083 |
| C006358 | acetohydroxamic acid | acetohydroxamic acid results in increased mutagenesis of HPRT1 gene | 4069149 |
| C091910 | acridine mustard | acridine mustard results in increased mutagenesis of HPRT1 gene | 2687635 |
| D020106 | Acrylamide | Acrylamide results in increased mutagenesis of HPRT1 gene | 18407966 |
| D020106 | Acrylamide | Acrylamide results in increased mutagenesis of HPRT1 gene | 15957192 |
| D020106 | Acrylamide | Acrylamide results in increased mutagenesis of HPRT1 gene | 20200216 |
| C079422 | acylfulvene | acylfulvene results in increased mutagenesis of HPRT1 gene | 23881331 |
| D000517 | alpha-Chlorohydrin | alpha-Chlorohydrin affects the expression of HPRT1 mRNA | 28522335 |
| C050234 | altertoxin II | altertoxin II results in increased mutagenesis of HPRT1 gene | 22902351 |
| D000638 | Amiodarone | Amiodarone affects the expression of HPRT1 mRNA | 19483382 |
| D000640 | Amitrole | Amitrole promotes the reaction [cadmium acetate results in increased mutagenesis of HPRT1 gene] | 8951241 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of HPRT1 mRNA | 16483693 |
| D001205 | Ascorbic Acid | [Ascorbic Acid results in increased susceptibility to chromium hexavalent ion] which results in increased mutagenesis of HPRT1 gene | 17169990 |
| D001205 | Ascorbic Acid | "Ascorbic Acid inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]" | 12467141 |
| D001280 | Atrazine | Atrazine results in increased mutagenesis of HPRT1 protein | 8379213 |
| D001280 | Atrazine | Atrazine results in increased expression of HPRT1 mRNA | 25929836 |
| D001280 | Atrazine | Atrazine results in decreased expression of HPRT1 mRNA | 22378314 |
| D001553 | Benzbromarone | Benzbromarone affects the expression of HPRT1 mRNA | 19483382 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | "benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene" | 17525473 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | "CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]" | 17525473 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | "GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]]" | 17525473 |
| C002615 | benzo(c)phenanthrene | benzo(c)phenanthrene analog affects the mutagenesis of HPRT1 gene | 11765016 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene analog affects the mutagenesis of HPRT1 gene | 11765016 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased mutagenesis of HPRT1 gene | 17525473|6777686 |
| D001564 | Benzo(a)pyrene | [Benzo(a)pyrene results in increased mutagenesis of HPRT1 gene] which results in increased susceptibility to Thioguanine | 6777686 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of HPRT1 mRNA | 16269432 |
| D001564 | Benzo(a)pyrene | CYP1A1 protein promotes the reaction [Benzo(a)pyrene results in increased mutagenesis of HPRT1 gene] | 17525473 |
| D001564 | Benzo(a)pyrene | [CYP1A1 protein results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene | 27913846 |
| D001564 | Benzo(a)pyrene | [CYP1A2 protein results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene | 27913846 |
| D001564 | Benzo(a)pyrene | [CYP1B1 protein results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene | 27913846 |
| D001564 | Benzo(a)pyrene | GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [Benzo(a)pyrene results in increased mutagenesis of HPRT1 gene]] | 17525473 |
| D001564 | Benzo(a)pyrene | [[POR protein co-treated with CYP3A4 protein] results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene | 27913846 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene affects the reaction [AHR protein binds to HPRT1 promoter] | 19654925 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of HPRT1 mRNA | 22228805 |
| D001564 | Benzo(a)pyrene | [2-hydroxychavicol co-treated with Benzo(a)pyrene] results in increased mutagenesis of HPRT1 gene | 15331132 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased mutagenesis of HPRT1 gene" | 22745795 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "POLH mutant form inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased mutagenesis of HPRT1 gene]" | 22745795 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased mutagenesis of HPRT1 gene" | 22745795 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "POLH mutant form inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased mutagenesis of HPRT1 gene]" | 22745795 |
| D019207 | beta Carotene | "beta Carotene inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]" | 12467141 |
| D004958 | Estradiol | Estradiol results in increased expression of HPRT1 mRNA | 22467019 |
| D004958 | Estradiol | Estradiol results in decreased expression of HPRT1 mRNA | 21984479 |
| D004958 | Estradiol | Estradiol results in increased expression of HPRT1 mRNA | 18709148 |
| D004958 | Estradiol | [bisphenol A co-treated with Estradiol] results in decreased expression of HPRT1 mRNA | 26496021 |
| C006780 | bisphenol A | bisphenol A affects the expression of HPRT1 mRNA | 21786754 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of HPRT1 mRNA | 29275510 |
| C006780 | bisphenol A | bisphenol A affects the expression of HPRT1 mRNA | 25181051 |
| C006780 | bisphenol A | [bisphenol A co-treated with Estradiol] results in decreased expression of HPRT1 mRNA | 26496021 |
| C006780 | bisphenol A | bisphenol A results in increased expression of HPRT1 protein | 22649256 |
| C013418 | bromfenacoum | bromfenacoum results in increased expression of HPRT1 protein | 28903499 |
| D002065 | Buspirone | Buspirone results in increased expression of HPRT1 mRNA | 24136188 |
| C028031 | cadmium acetate | Amitrole promotes the reaction [cadmium acetate results in increased mutagenesis of HPRT1 gene] | 8951241 |
| C028031 | cadmium acetate | cadmium acetate results in increased mutagenesis of HPRT1 gene | 8951241 |
| C028031 | cadmium acetate | Mannitol inhibits the reaction [cadmium acetate results in increased mutagenesis of HPRT1 gene] | 8951241 |
| D019256 | Cadmium Chloride | Cadmium Chloride affects the expression of HPRT1 mRNA | 18804290 |
| D002110 | Caffeine | Caffeine results in increased expression of HPRT1 protein | 6149265 |
| D002215 | Captan | Captan results in increased mutagenesis of HPRT1 gene | 7274179 |
| D002215 | Captan | [Captan results in increased mutagenesis of HPRT1 gene] which results in decreased susceptibility to Thioguanine | 7274179 |
| D002218 | Carbadox | Carbadox results in increased mutagenesis of HPRT1 gene | 23063596 |
| D002330 | Carmustine | Carmustine results in increased mutagenesis of HPRT1 gene | 17116724 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of HPRT1 mRNA | 23650126 |
| C023600 | chromic oxide | chromic oxide results in increased mutagenesis of HPRT1 gene | 1423875 |
| C074702 | chromium hexavalent ion | [Ascorbic Acid results in increased susceptibility to chromium hexavalent ion] which results in increased mutagenesis of HPRT1 gene | 17169990 |
| C074702 | chromium hexavalent ion | chromium hexavalent ion results in increased mutagenesis of HPRT1 gene | 1423875|17169990 |
| C074702 | chromium hexavalent ion | chromium hexavalent ion results in increased mutagenesis of HPRT1 gene | 7508562 |
| C012843 | cinnamic aldehyde | cinnamic aldehyde results in decreased mutagenesis of HPRT1 gene | 17178418 |
| D002994 | Clofibrate | Clofibrate affects the expression of HPRT1 mRNA | 19483382 |
| D002995 | Clofibric Acid | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HPRT1 mRNA | 17602206 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of HPRT1 mRNA | 19320972 |
| D003375 | Coumestrol | "[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HPRT1 mRNA" | 19167446 |
| D003375 | Coumestrol | [Coumestrol co-treated with resveratrol] results in increased expression of HPRT1 mRNA | 19167446 |
| D003375 | Coumestrol | Coumestrol results in increased expression of HPRT1 mRNA | 19167446 |
| D003474 | Curcumin | Curcumin results in increased expression of HPRT1 mRNA | 16101141 |
| C007168 | cyanazine | cyanazine results in increased mutagenesis of HPRT1 protein | 8379213 |
| D003520 | Cyclophosphamide | Cyclophosphamide results in increased mutagenesis of HPRT1 gene | 17116724 |
| D003520 | Cyclophosphamide | Cyclophosphamide results in increased mutagenesis of HPRT1 gene | 23677247 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of HPRT1 mRNA | 27989131 |
| D003687 | Dehydroepiandrosterone | Dehydroepiandrosterone results in increased expression of HPRT1 mRNA | 18709148 |
| C460375 | dibenz(c,h)acridine | "dibenz(c,h)acridine analog affects the mutagenesis of HPRT1 gene" | 11765016 |
| D015946 | Ethylene Dibromide | Ethylene Dibromide results in increased mutagenesis of HPRT1 gene | 9491396 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate promotes the reaction [[Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene] | 15613823 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in increased mutagenesis of HPRT1 gene | 15613823 |
| D003993 | Dibutyl Phthalate | [Ozone co-treated with Dibutyl Phthalate] results in increased mutagenesis of HPRT1 gene | 15613823 |
| D004042 | Dietary Fats, Unsaturated | "Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of HPRT1 mRNA]" | 23626681 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in increased expression of HPRT1 mRNA | 19850644 |
| D004051 | Diethylhexyl Phthalate | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of HPRT1 mRNA] | 19850644 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HPRT1 mRNA | 17602206 |
| D002117 | Calcitriol | Calcitriol results in decreased expression of HPRT1 mRNA | 21592394 |
| D002117 | Calcitriol | [Testosterone co-treated with Calcitriol] results in decreased expression of HPRT1 mRNA | 21592394 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | "9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HPRT1 gene" | 6777686 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | "[9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HPRT1 gene] which results in increased susceptibility to Thioguanine" | 6777686 |
| D004128 | Dimethylnitrosamine | [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to Dimethylnitrosamine] which results in increased mutagenesis of HPRT1 gene | 27913846 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide results in decreased expression of HPRT1 mRNA | 12883083 |
| C070609 | EMD 53998 | EMD 53998 analog results in increased expression of HPRT1 mRNA | 24977338 |
| D004785 | Environmental Pollutants | Environmental Pollutants results in decreased expression of HPRT1 mRNA | 24534155 |
| D004791 | Enzyme Inhibitors | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of HPRT1 protein | 23301498 |
| C007366 | erythritol anhydride | erythritol anhydride results in increased mutagenesis of HPRT1 exon | 12521305 |
| C007366 | erythritol anhydride | erythritol anhydride results in increased mutagenesis of HPRT1 gene SNP | 12521305 |
| C007366 | erythritol anhydride | erythritol anhydride results in increased mutagenesis of HPRT1 gene | 20853577 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of HPRT1 mRNA | 17555576|1794274 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HPRT1 mRNA | 17942748 |
| D005001 | Ethionine | Ethionine affects the expression of HPRT1 mRNA | 19483382 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in increased mutagenesis of HPRT1 gene | 10727902|2687635 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in increased mutagenesis of HPRT1 gene | 7728755 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in increased mutagenesis of HPRT1 gene | 17066413 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in increased mutagenesis of HPRT1 gene | 22167886 |
| C082360 | fipronil | fipronil results in increased expression of HPRT1 mRNA | 23962444 |
| C005020 | folpet | folpet results in increased mutagenesis of HPRT1 gene | 7274179 |
| C005020 | folpet | [folpet results in increased mutagenesis of HPRT1 gene] which results in decreased susceptibility to Thioguanine | 7274179 |
| D019833 | Genistein | Genistein results in decreased expression of HPRT1 mRNA | 22228119 |
| C071834 | glycidamide | glycidamide results in increased mutagenesis of HPRT1 gene | 15957192 |
| C071834 | glycidamide | glycidamide results in increased mutagenesis of HPRT1 gene | 20200216 |
| C007870 | glycidyl methacrylate | glycidyl methacrylate results in increased mutagenesis of HPRT1 gene | 9711268 |
| D006046 | Gold | Gold results in decreased expression of HPRT1 mRNA | 25523186 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased mutagenesis of HPRT1 gene | 22539617|7508562 |
| D006918 | Hydroxyurea | CAT protein inhibits the reaction [Hydroxyurea analog results in increased mutagenesis of HPRT1 gene] | 4069149 |
| D006918 | Hydroxyurea | Hydroxyurea analog results in increased mutagenesis of HPRT1 gene | 4069149 |
| D006997 | Hypochlorous Acid | Hypochlorous Acid results in increased mutagenesis of HPRT1 gene | 19892774 |
| C008105 | illudin S | illudin S results in increased mutagenesis of HPRT1 gene | 23881331 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HPRT1 mRNA | 25613284 |
| C102714 | irofulven | irofulven results in increased mutagenesis of HPRT1 gene | 23881331 |
| D007538 | Isoniazid | Isoniazid results in increased expression of HPRT1 mRNA | 12883083 |
| C008261 | lead acetate | lead acetate results in decreased activity of HPRT1 protein | 19428946 |
| C008261 | lead acetate | lead acetate results in decreased activity of HPRT1 protein | 19428946 |
| C031895 | lead chromate | lead chromate results in increased mutagenesis of HPRT1 gene | 1423875 |
| D001556 | Lindane | Lindane results in decreased expression of HPRT1 mRNA | 17785943 |
| D008094 | Lithium | Lithium results in increased expression of HPRT1 protein | 18296634 |
| D008353 | Mannitol | Mannitol inhibits the reaction [cadmium acetate results in increased mutagenesis of HPRT1 gene] | 8951241 |
| C545385 | Mequindox | Mequindox results in increased mutagenesis of HPRT1 gene | 23063596 |
| D008701 | Methapyrilene | Methapyrilene results in increased expression of HPRT1 mRNA | 28935588 |
| D008727 | Methotrexate | Methotrexate results in decreased expression of HPRT1 mRNA | 17400583 |
| D008731 | Methoxychlor | Methoxychlor results in increased methylation of HPRT1 gene | 23303685 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in decreased expression of HPRT1 mRNA | 18804290 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in increased mutagenesis of HPRT1 gene | 2687635 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in increased expression of HPRT1 mRNA | 26011545 |
| D008770 | Methylnitrosourea | Methylnitrosourea results in increased mutagenesis of HPRT1 gene | 18249417 |
| C568376 | MT19c compound | MT19c compound results in increased expression of HPRT1 mRNA | 21781307 |
| C014117 | mucochloric acid | mucochloric acid results in increased mutagenesis of HPRT1 gene | 7607182 |
| C000621033 | napabucasin | napabucasin results in decreased expression of HPRT1 mRNA | 25605917 |
| C078255 | N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased mutagenesis of HPRT1 gene" | 7728948 |
| C051752 | nefazodone | nefazodone results in increased expression of HPRT1 mRNA | 24136188 |
| C011286 | N-hydroxyurethane | N-hydroxyurethane results in increased mutagenesis of HPRT1 gene | 4069149 |
| C029938 | nickel sulfate | nickel sulfate affects the expression of HPRT1 mRNA | 18202158 |
| C012655 | nimesulide | nimesulide results in increased expression of HPRT1 mRNA | 24136188 |
| D009569 | Nitric Oxide | Nitric Oxide results in increased mutagenesis of HPRT1 gene | 22303861|2845427 |
| D015112 | 4-Nitroquinoline-1-oxide | 4-Nitroquinoline-1-oxide results in increased mutagenesis of HPRT1 gene | 26362870|2845427 |
| C014707 | nitrosobenzylmethylamine | nitrosobenzylmethylamine results in increased expression of HPRT1 mRNA | 17616710 |
| C041150 | N-methyl-7H-dibenzo(c,g)carbazole | "[CYP3A4 protein results in increased metabolism of N-methyl-7H-dibenzo(c,g)carbazole] which results in increased mutagenesis of HPRT1 exon" | 21798277 |
| C013168 | olaquindox | olaquindox results in increased mutagenesis of HPRT1 gene | 23774262 |
| D009853 | Omeprazole | Omeprazole affects the expression of HPRT1 mRNA | 19483382 |
| D010126 | Ozone | Dibutyl Phthalate promotes the reaction [[Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene] | 15613823 |
| D010126 | Ozone | [Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene | 15613823 |
| D010126 | Ozone | [Ozone co-treated with Dibutyl Phthalate] results in increased mutagenesis of HPRT1 gene | 15613823 |
| D010126 | Ozone | Ozone results in increased mutagenesis of HPRT1 gene | 15613823 |
| D010269 | Paraquat | Paraquat results in increased expression of HPRT1 mRNA | 21371552 |
| D010416 | Pentachlorophenol | Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene] | 25243916 |
| D010416 | Pentachlorophenol | Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] | 25243916 |
| C036567 | perfluorodecanoic acid | perfluorodecanoic acid results in decreased expression of HPRT1 mRNA | 21984479 |
| C101816 | perfluoro-n-nonanoic acid | perfluoro-n-nonanoic acid results in decreased expression of HPRT1 mRNA | 21984479 |
| C076994 | perfluorooctane sulfonic acid | perfluorooctane sulfonic acid results in increased expression of HPRT1 mRNA | 21984479 |
| C023036 | perfluorooctanoic acid | "Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of HPRT1 mRNA]" | 23626681 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in increased expression of HPRT1 mRNA | 23626681 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in increased expression of HPRT1 mRNA | 18709148 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in decreased expression of HPRT1 mRNA | 18804290 |
| D010634 | Phenobarbital | Phenobarbital results in decreased expression of HPRT1 mRNA | 16940010 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of HPRT1 mRNA | 18301758|2081375 |
| C006253 | pirinixic acid | pirinixic acid affects the expression of HPRT1 mRNA | 19483382 |
| C019536 | potassium bromate | potassium bromate results in increased mutagenesis of HPRT1 gene | 22539617 |
| D011192 | Potassium Dichromate | Potassium Dichromate results in increased mutagenesis of HPRT1 gene | 1423875 |
| D011192 | Potassium Dichromate | Potassium Dichromate results in increased mutagenesis of HPRT1 gene | 7508562 |
| C045950 | propiconazole | propiconazole results in increased expression of HPRT1 mRNA | 21278054 |
| D011441 | Propylthiouracil | Propylthiouracil affects the expression of HPRT1 mRNA | 19483382 |
| D011748 | Pyrogallol | Pyrogallol results in increased expression of HPRT1 mRNA | 20362636 |
| D011794 | Quercetin | Quercetin results in increased mutagenesis of HPRT1 protein | 8379213 |
| C502851 | quinocetone | quinocetone results in increased mutagenesis of HPRT1 gene | 23774262 |
| C059514 | resveratrol | [Coumestrol co-treated with resveratrol] results in increased expression of HPRT1 mRNA | 19167446 |
| C059514 | resveratrol | resveratrol results in decreased expression of HPRT1 protein | 23724044 |
| C009166 | retinol acetate | retinol acetate results in increased expression of HPRT1 mRNA | 16772331 |
| C009277 | sodium arsenate | sodium arsenate results in increased expression of HPRT1 mRNA | 23922661 |
| C017947 | sodium arsenite | APEX1 inhibits the reaction [[ATF4 mutant form results in increased susceptibility to sodium arsenite] which results in increased mutagenesis of HPRT1 gene] | 17938202 |
| C017947 | sodium arsenite | [ATF4 mutant form results in increased susceptibility to sodium arsenite] which results in increased mutagenesis of HPRT1 gene | 17938202 |
| D020058 | Styrene | GSTP1 gene polymorphism promotes the reaction [Styrene results in increased mutagenesis of HPRT1 gene] | 12893075 |
| D020058 | Styrene | Styrene results in increased mutagenesis of HPRT1 gene | 11535253|1289307 |
| C446685 | systhane | systhane results in increased expression of HPRT1 mRNA | 25461557 |
| D013629 | Tamoxifen | Tamoxifen affects the expression of HPRT1 mRNA | 17555576 |
| C047246 | temozolomide | MGMT protein inhibits the reaction [temozolomide results in increased mutagenesis of HPRT1 gene] | 17116724 |
| C047246 | temozolomide | temozolomide results in increased mutagenesis of HPRT1 gene | 17116724 |
| D013739 | Testosterone | [Testosterone co-treated with Calcitriol] results in decreased expression of HPRT1 mRNA | 21592394 |
| D013739 | Testosterone | Testosterone results in decreased expression of HPRT1 mRNA | 21592394 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of HPRT1 mRNA | 22574217 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of HPRT1 mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the reaction [AHR protein binds to HPRT1 promoter] | 19654925 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HPRT1 mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of HPRT1 mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of HPRT1 mRNA | 21215274 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HPRT1 mRNA | 25613284 |
| D015647 | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine | "2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of HPRT1 protein" | 25852303 |
| D019284 | Thapsigargin | Thapsigargin results in decreased expression of HPRT1 mRNA | 22378314 |
| D013853 | Thioacetamide | Thioacetamide affects the expression of HPRT1 mRNA | 19483382 |
| D013866 | Thioguanine | "[9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HPRT1 gene] which results in increased susceptibility to Thioguanine" | 6777686 |
| D013866 | Thioguanine | [Benzo(a)pyrene results in increased mutagenesis of HPRT1 gene] which results in increased susceptibility to Thioguanine | 6777686 |
| D013866 | Thioguanine | [Captan results in increased mutagenesis of HPRT1 gene] which results in decreased susceptibility to Thioguanine | 7274179 |
| D013866 | Thioguanine | [folpet results in increased mutagenesis of HPRT1 gene] which results in decreased susceptibility to Thioguanine | 7274179 |
| D013866 | Thioguanine | HPRT1 gene mutant form results in decreased susceptibility to Thioguanine | 21798277 |
| D013866 | Thioguanine | HPRT1 gene mutant form results in decreased susceptibility to Thioguanine | 28446605 |
| C009495 | titanium dioxide | titanium dioxide results in increased mutagenesis of HPRT1 gene | 28400324 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of HPRT1 mRNA | 21934132|2372400 |
| D014212 | Tretinoin | Tretinoin results in increased expression of HPRT1 mRNA | 24977338 |
| C015559 | trimellitic anhydride | trimellitic anhydride results in increased expression of HPRT1 mRNA | 19042947 |
| C057693 | troglitazone | troglitazone results in decreased expression of HPRT1 mRNA | 19631733 |
| D014415 | Tunicamycin | Tunicamycin results in decreased expression of HPRT1 mRNA | 22378314 |
| D014635 | Valproic Acid | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HPRT1 mRNA" | 27188386 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of HPRT1 mRNA | 23179753|2627250 |
| C100058 | vanillin | vanillin results in decreased mutagenesis of HPRT1 gene | 17178418 |
| D014810 | Vitamin E | "Vitamin E inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]" | 12467141 |
| D015215 | Zidovudine | Zidovudine results in increased mutagenesis of HPRT1 exon | 10526209 |