Gene: BIRC5

332
API4|EPR-1
baculoviral IAP repeat containing 5
protein-coding
17q25.3
Ensembl:ENSG00000089685 MIM:603352 Vega:OTTHUMG00000177505 UniprotKB:O15392
NG_029069.1
PubMed|SNP Mapped
ND|AD
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.047e-1 (AD)  6.277e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2071214chr17:78223510 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TROAP0.67
MKI670.666
KIF20A0.642
AURKB0.637
TOP2A0.624
MYBL20.614
RRM20.578
CEP550.577
CCNB20.571
NDC800.558

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ABCD2-0.344
WNT3-0.315
ARSF-0.309
CRH-0.307
WIF1-0.3
KIT-0.293
VIP-0.288
GAD2-0.285
HAPLN1-0.28
LYPD6-0.279

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00206ReserpineSmall Molecule50-55-5Approved|InvestigationalTarget
DB04115BerberineSmall Molecule2086-83-1Approved|InvestigationalTarget
DB05141LY2181308Small Molecule-InvestigationalTarget
ID Drug Name Action PubMed
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [EP300 protein binds to BIRC5 promoter]"20660371
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased expression of BIRC5 mRNA"20660371
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased expression of BIRC5 protein"20660371|2603571
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased expression of BIRC5 mRNA]"20660371
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased expression of BIRC5 protein]"20660371
C50489712-(3-adamantan-1-ylureido)dodecanoic acid12-(3-adamantan-1-ylureido)dodecanoic acid results in decreased expression of BIRC5 mRNA19435785
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of BIRC5 mRNA"26377693
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of BIRC5 mRNA"21391223|2890350
C0479481'-acetoxychavicol acetate1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]15905586
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BIRC5 mRNA"25510870
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naphtho(1,2-b)furan-4,5-dione results in decreased expression of BIRC5 protein]"19747539
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]18377872
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of BIRC5 protein18710790
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of BIRC5 mRNA"19114083
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BIRC5 mRNA"19167446
C0630022,3-dimethoxy-1,4-naphthoquinone"2,3-dimethoxy-1,4-naphthoquinone results in increased expression of BIRC5 mRNA"19031421
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BIRC5 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BIRC5 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BIRC5 mRNA"25510870
C5622542'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione"2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of BIRC5 protein"21741372
C5622542'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione"Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of BIRC5 protein]"21741372
C0109142,4-diaminotoluene"2,4-diaminotoluene results in increased expression of BIRC5 mRNA"20713471
C0593542',4'-dihydroxychalcone"2',4'-dihydroxychalcone results in decreased expression of BIRC5 mRNA"20471467
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Tamoxifen] results in decreased expression of BIRC5 mRNA22046442
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Tamoxifen] results in decreased expression of BIRC5 protein22046442
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CALCA protein results in increased expression of BIRC5 protein]16222118
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]21594580
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Simvastatin results in decreased expression of BIRC5 protein]20464445
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of BIRC5 mRNA15065019
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of BIRC5 protein15065019|1747296
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of BIRC5 mRNA22046442
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneSimvastatin promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of BIRC5 protein]20464445
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cisplatin results in increased expression of BIRC5 mRNA]20514400
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BIRC5 mRNA"25510870
C4882882,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid"[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of BIRC5 protein"18444175
C4882882,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid"2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid results in decreased expression of BIRC5 protein"18444175
C5066982,5-dimethylcelecoxib"2,5-dimethylcelecoxib results in decreased expression of BIRC5 protein"16123214|1670702
C55788225-methoxyldammarane-3,12,20-triol"25-methoxyldammarane-3,12,20-triol results in decreased expression of BIRC5 protein"21924252
C0038982-anisidine2-anisidine results in decreased expression of BIRC5 mRNA28089782
C5264372-methoxy-3-O-sulfamoyl-17-cyanomethylestra-1,3,5(10)-triene"2-methoxy-3-O-sulfamoyl-17-cyanomethylestra-1,3,5(10)-triene results in decreased expression of BIRC5 protein"19846905
C5264382-methoxyestradiol-3,17-O,O-bis(sulfamate)"2-methoxyestradiol-3,17-O,O-bis(sulfamate) results in decreased expression of BIRC5 protein"19846905
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in decreased expression of BIRC5 mRNA]28655636
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in decreased expression of BIRC5 mRNA]28655636
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in decreased expression of BIRC5 protein"22290291
C4824923,4,5,4'-tetramethoxystilbene"3,4,5,4'-tetramethoxystilbene results in decreased expression of BIRC5 protein"23770989
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]"23452621
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"4-(3,5-dimethoxystyryl)phenyl acetate results in decreased expression of BIRC5 protein"26138072
C0888604-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [betulinic acid results in increased expression of BIRC5]"16077934
C0888604-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Paclitaxel results in increased expression of BIRC5]"16211241
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of BIRC5 mRNA"18648102
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Nitroprusside results in decreased expression of BIRC5 protein]14988404
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [oxaliplatin results in decreased expression of BIRC5 protein]20708607
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [S-nitro-N-acetylpenicillamine results in decreased expression of BIRC5 protein]14988404
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole affects the reaction [BIRC5 protein results in decreased susceptibility to oxaliplatin]20708607
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BIRC5 mRNA"27188386
C5066064-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide"[4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide co-treated with Paclitaxel] results in decreased expression of BIRC5 protein"16170024
C5066064-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide"4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide results in decreased expression of BIRC5 protein"16170024
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of BIRC5 mRNA19191707
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of BIRC5 mRNA19191707
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone affects the localization of and results in increased expression of BIRC5 protein21776270
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BIRC5 mRNA21167638
C546624(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol"(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol inhibits the reaction [N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide results in increased expression of and affects the localization of BIRC5 protein]"24444656
C5805985-OH-BDE-475-OH-BDE-47 results in decreased expression of BIRC5 mRNA27589474
C4718436-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine promotes the reaction [Nitroprusside results in decreased expression of BIRC5 mRNA]14988404
C4718436-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine results in decreased expression of BIRC5 protein15958644|1617002
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BIRC5 mRNA"27188386
C5605976,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide"6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide binds to and results in decreased activity of BIRC5 protein"23994265
C5805996-OH-BDE-476-OH-BDE-47 results in decreased expression of BIRC5 mRNA27589474
C0548527-hydroxystaurosporine[alvocidib co-treated with 7-hydroxystaurosporine] results in decreased expression of BIRC5 protein16012789
C0548527-hydroxystaurosporineBIRC5 protein results in decreased susceptibility to 7-hydroxystaurosporine16012789
C542662AC 93253AC 93253 results in decreased expression of BIRC5 mRNA25912555
D000082AcetaminophenAcetaminophen results in decreased expression of BIRC5 mRNA29067470
D000082AcetaminophenAcetaminophen results in increased expression of BIRC5 mRNA22230336
D000082AcetaminophenAcetaminophen results in decreased expression of BIRC5 mRNA17942131
D000082AcetaminophenAcetaminophen results in increased expression of BIRC5 protein20100502
D000082AcetaminophenCAV1 affects the reaction [Acetaminophen results in increased expression of BIRC5 protein]20100502
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of BIRC5 protein]"21741372
D000111AcetylcysteineAcetylcysteine inhibits the reaction [gingerol results in decreased expression of BIRC5 protein]25034532
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BIRC5 protein]23711929
D020106AcrylamideAcrylamide results in increased expression of BIRC5 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 affects the expression of BIRC5 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of BIRC5 mRNA19770486
C038491allyl sulfideallyl sulfide results in decreased expression of BIRC5 protein17647244
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased expression of BIRC5 mRNA"24587049
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased expression of BIRC5 protein"20197088|2458704
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of STAT3 protein] which results in decreased expression of BIRC5 protein"18592012
C077990alvocidib[alvocidib co-treated with 7-hydroxystaurosporine] results in decreased expression of BIRC5 protein16012789
C077990alvocidib[alvocidib co-treated with PBOX-6] results in decreased expression of BIRC5 protein20206141
C077990alvocidibalvocidib inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of BIRC5 protein]12517802
C077990alvocidibalvocidib results in decreased expression of BIRC516820931
C077990alvocidibalvocidib results in decreased expression of BIRC5 mRNA12517783
C077990alvocidibalvocidib results in decreased expression of BIRC5 protein12517783
C077990alvocidibalvocidib results in decreased phosphorylation of and results in decreased expression of BIRC5 protein12517802
D000638AmiodaroneAmiodarone results in decreased expression of BIRC5 protein21224497
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of BIRC5 mRNA"22863853
C088115anacardic acidanacardic acid inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]18349320
C030419andrographolideandrographolide results in decreased expression of BIRC5 protein23845849
D000841AnisomycinAnisomycin promotes the reaction [(+)-JQ1 compound results in decreased expression of BIRC5 protein]23872705
C558369antrocinantrocin results in decreased expression of BIRC5 mRNA21158420
C558369antrocinantrocin results in decreased expression of BIRC5 protein21158420
D001151Arsenic[Arsenic co-treated with Fluorides] results in increased expression of BIRC5 mRNA19962721
C058317arsenic disulfidearsenic disulfide results in decreased expression of BIRC515972126
C006632arsenic trioxide2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]21594580
C006632arsenic trioxidearsenic trioxide affects the expression of BIRC5 mRNA18088464
C006632arsenic trioxide[arsenic trioxide co-treated with Curcumin] results in decreased expression of BIRC5 protein27430728
C006632arsenic trioxide[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BIRC5 mRNA24738333
C006632arsenic trioxide[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BIRC5 protein24738333
C006632arsenic trioxide[arsenic trioxide co-treated with Ethacrynic Acid] results in decreased expression of BIRC5 protein23082001
C006632arsenic trioxide[arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of BIRC5 mRNA19825857
C006632arsenic trioxide[arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of BIRC5 protein19825857
C006632arsenic trioxidearsenic trioxide promotes the reaction [matrine results in decreased expression of BIRC5 protein]23700110
C006632arsenic trioxidearsenic trioxide promotes the reaction [puerarin results in decreased expression of BIRC5 mRNA]20416161
C006632arsenic trioxidearsenic trioxide results in decreased expression of BIRC521473291
C006632arsenic trioxidearsenic trioxide results in decreased expression of BIRC5 mRNA16638212|1786904
C006632arsenic trioxidearsenic trioxide results in decreased expression of BIRC5 protein16328441|1663821
C006632arsenic trioxidearsenic trioxide results in increased expression of BIRC5 mRNA15587394
C006632arsenic trioxidearsenic trioxide results in increased expression of BIRC5 protein15587394|2743072
C006632arsenic trioxide[arsenic trioxide results in increased susceptibility to PD 173074] which results in decreased expression of BIRC5 protein27794399
C006632arsenic trioxideBIRC5 protein affects the susceptibility to arsenic trioxide20635649
C006632arsenic trioxideBIRC5 protein results in decreased susceptibility to arsenic trioxide15587394|2743072
C006632arsenic trioxideGH1 protein promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 mRNA]23851143
C006632arsenic trioxidematrine promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]23700110
C006632arsenic trioxidePoly I-C promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]21418039
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]16328441|2159458
C006632arsenic trioxideSB 203580 inhibits the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]16328441|2159458
C006632arsenic trioxide[silybin co-treated with arsenic trioxide] results in decreased expression of BIRC5 mRNA21969006
C006632arsenic trioxide[Sulindac co-treated with arsenic trioxide] results in decreased expression of BIRC5 protein18281123
C006632arsenic trioxideU 0126 inhibits the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]21594580
C006632arsenic trioxide"arsenic trioxide promotes the reaction [Drugs, Chinese Herbal results in decreased expression of BIRC5 protein]"28587418
C006632arsenic trioxidearsenic trioxide results in decreased expression of BIRC5 protein28587418
C006632arsenic trioxide"Drugs, Chinese Herbal promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]"28587418
C006632arsenic trioxidearsenic trioxide results in decreased expression of BIRC5 protein23444241
C015001arsenitearsenite results in decreased expression of BIRC5 mRNA18585952
C015001arseniteXPA protein affects the reaction [arsenite results in decreased expression of BIRC5 mRNA]18585952
C015001arsenitearsenite results in decreased expression of BIRC5 mRNA18929588
C519899AS602868AS602868 results in decreased expression of BIRC5 mRNA18182997
C519899AS602868irinotecan promotes the reaction [AS602868 results in decreased expression of BIRC5 mRNA]18182997
D001205Ascorbic AcidAscorbic Acid results in decreased expression of BIRC5 mRNA21919647
D001241Aspirin[Aspirin co-treated with TNFSF10 protein] results in decreased expression of BIRC5 protein18483385
D001241AspirinAspirin inhibits the reaction [E2F1 protein binds to BIRC5 promoter]17848598
D001241AspirinAspirin results in decreased expression of BIRC5 mRNA17848598
D001241AspirinAspirin results in decreased expression of BIRC5 protein17848598|1848338
D001241AspirinAspirin results in increased expression of BIRC5 mRNA11906190|1734232
D001241Aspirinepoxomicin inhibits the reaction [Aspirin results in decreased expression of BIRC5 protein]18483385
D001241AspirinAspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased expression of BIRC5 mRNA17372815
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased expression of BIRC5 protein17372815
D001280AtrazineAtrazine results in decreased expression of BIRC5 mRNA22378314
C010329azadirachtinazadirachtin results in decreased expression of BIRC5 protein20429769
D001379AzathioprineAzathioprine results in decreased expression of BIRC5 mRNA22623647
C547126AZM551248AZM551248 results in increased expression of BIRC5 mRNA22323515
D001397AzoxymethaneAspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
D001397Azoxymethane[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein25449198
D001397AzoxymethaneCamptothecin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
D001397AzoxymethanePlant Extracts inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
C006680baicaleinbaicalein results in decreased expression of BIRC5 protein18025287
C006680baicaleinSB 203580 inhibits the reaction [baicalein results in decreased expression of BIRC5 protein]18025287
C006680baicaleinwortmannin promotes the reaction [baicalein results in decreased expression of BIRC5 protein]18025287
C012765bakuchiolbakuchiol results in decreased expression of BIRC5 protein27033605
C487081belinostatbelinostat results in decreased expression of BIRC5 mRNA19606018
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of BIRC5 mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene affects the localization of and results in increased expression of BIRC5 protein21776270
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of BIRC5 mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of BIRC5 mRNA26377693
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BIRC5 mRNA18164116
D019817Benzoic AcidBenzoic Acid analog inhibits the reaction [STAT3 protein binds to BIRC5 promoter]26088127
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased expression of BIRC5 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BIRC5 mRNA20064835|2163298
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BIRC5 protein24664296
D001564Benzo(a)pyreneCurcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein]24664296
D001564Benzo(a)pyreneVitamin E inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein]24664296
D001564Benzo(a)pyreneAHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 mRNA]15034205
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of BIRC5 mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BIRC5 mRNA15034205|1794213
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BIRC5 mRNA21964900|2649674
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BIRC5 mRNA"20382639
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of BIRC5 mRNA"19150397
D003374CoumarinsCoumarins analog results in decreased expression of BIRC5 protein25231984
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]19939880
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound results in decreased expression of BIRC5 protein]23872705
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of BIRC5 protein]19812371
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]17548900
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to [oxaliplatin results in decreased expression of BIRC5 protein]20708607
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC5 protein16328441|1751042
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of BIRC5 protein]19812371
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BIRC5 mRNA25566086
C027870berbamineberbamine binds to BIRC5 promoter17968851
C027870berbamineberbamine results in decreased expression of BIRC5 mRNA17531122
C027870berbamineberbamine results in decreased expression of BIRC5 protein19960011
D001599BerberineBerberine binds to BIRC5 promoter17968851
D004958EstradiolEstradiol affects the expression of BIRC5 mRNA21826169
D004958EstradiolEstradiol inhibits the reaction [Etoposide results in increased expression of BIRC5 mRNA]19426747
D004958EstradiolEstradiol results in decreased expression of BIRC5 mRNA19426747
D004958EstradiolEstradiol results in increased expression of BIRC5 mRNA16474171|1670574
D004958EstradiolESR1 protein promotes the reaction [Estradiol results in increased expression of BIRC5 mRNA]25210133
D004958EstradiolEstradiol results in increased expression of BIRC5 mRNA25210133
D004958EstradiolEstradiol results in increased expression of BIRC5 mRNA21980073
C044887beta-methylcholinebeta-methylcholine affects the expression of BIRC5 mRNA21179406
C002503betulinbetulin analog promotes the reaction [Oxygen deficiency results in decreased expression of BIRC5 protein]26540049
C002503betulinbetulin analog results in decreased expression of BIRC5 protein26540049
C002070betulinic acid"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [betulinic acid results in increased expression of BIRC5]"16077934
C002070betulinic acidbetulinic acid promotes the reaction [Oxygen deficiency results in decreased expression of BIRC5 protein]26540049
C002070betulinic acidbetulinic acid results in decreased expression of BIRC5 protein26540049
C002070betulinic acidbetulinic acid results in increased expression of BIRC516077934
C002070betulinic acidBIRC5 protein results in decreased susceptibility to betulinic acid16077934
C095105bexarotenebexarotene results in decreased expression of BIRC5 protein19067706
C095105bexarotenebexarotene results in decreased expression of BIRC5 mRNA17849452
C053541bicalutamidebicalutamide results in decreased expression of BIRC5 mRNA15638997
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in increased expression of BIRC5 mRNA27685785
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of BIRC5 mRNA28628672
C006780bisphenol Abisphenol A results in decreased expression of BIRC5 mRNA27561114
C006780bisphenol Abisphenol A affects the expression of BIRC5 mRNA21826169
C006780bisphenol Abisphenol A results in decreased expression of BIRC5 mRNA27979917|2927551
C006780bisphenol Abisphenol A results in increased expression of BIRC5 mRNA16474171
C006780bisphenol Abisphenol A results in increased expression of BIRC5 protein19270784
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of BIRC5 mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of BIRC5 mRNA27623287
C006780bisphenol Abisphenol A results in decreased expression of BIRC5 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of BIRC5 mRNA18180321
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of BIRC5 mRNA17942131
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of BIRC5 mRNA17553608
D001761BleomycinBleomycin results in increased expression of BIRC5 mRNA26345256
D000069286BortezomibBortezomib results in decreased expression of BIRC5 mRNA17898295|2097792
D000069286BortezomibBortezomib results in decreased expression of BIRC5 protein18850583|1963629
D000069286BortezomibBortezomib results in increased expression of BIRC5 protein17510429
D000069286Bortezomib[irinotecan co-treated with Bortezomib] results in decreased expression of BIRC5 protein16373703
D000069286Bortezomib[romidepsin co-treated with Bortezomib] results in increased cleavage of BIRC5 protein18223231
D000069286BortezomibBortezomib results in decreased expression of BIRC5 protein18451165
C000595192BP-1-102BP-1-102 analog inhibits the reaction [STAT3 protein binds to BIRC5 promoter]26088127
C000595192BP-1-102BP-1-102 analog results in decreased expression of BIRC5 protein26088127
D001973Bromodeoxyuridine[Bromodeoxyuridine co-treated with furan] results in increased expression of BIRC5 mRNA24910943
C514835bromotetrandrine[bromotetrandrine co-treated with Daunorubicin] results in decreased expression of BIRC5 mRNA21362215
C514835bromotetrandrine[bromotetrandrine co-treated with Daunorubicin] results in decreased expression of BIRC5 protein21362215
C514835bromotetrandrine[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of BIRC5 mRNA21720514
C514835bromotetrandrine[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of BIRC5 protein21720514
C514835bromotetrandrine[Daunorubicin co-treated with bromotetrandrine] results in decreased expression of BIRC5 mRNA21720514
C514835bromotetrandrine[Daunorubicin co-treated with bromotetrandrine] results in decreased expression of BIRC5 protein21720514
D019819BudesonideBudesonide results in decreased expression of BIRC5 mRNA17163412
C048491butaprostbutaprost inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased expression of BIRC5 protein]21268125
C048491butaprostbutaprost results in increased expression of BIRC5 protein21268125
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of BIRC5 mRNA15003993
D002085Butylhydroxybutylnitrosamine[Butylhydroxybutylnitrosamine co-treated with Propolis analog] results in increased expression of BIRC5 mRNA26111810
D002087Butyrates[Butyrates co-treated with Camptothecin] results in decreased expression of BIRC5 protein16061681
D002087ButyratesButyrates results in decreased expression of BIRC5 mRNA16042588
D002087ButyratesButyrates results in decreased expression of BIRC5 protein16007142
D002166Camptothecin[Butyrates co-treated with Camptothecin] results in decreased expression of BIRC5 protein16061681
D002166CamptothecinCamptothecin results in decreased expression of BIRC5 mRNA24726431
D002166CamptothecinCamptothecin results in increased expression of BIRC5 mRNA24726431
D002166CamptothecinCamptothecin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
D002193CantharidinCantharidin results in decreased expression of BIRC5 protein16117893
C464842CanvaxinBIRC5 results in decreased susceptibility to Canvaxin15986442
D002211Capsaicinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]19939880
D002211CapsaicinBIRC5 results in decreased activity of [Capsaicin co-treated with TNFSF10 protein]19939880
D002211CapsaicinCapsaicin results in decreased expression of BIRC519002586
D002211CapsaicinCapsaicin results in decreased expression of BIRC5 protein17505005|1993988
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of BIRC5 mRNA17484886|2733941
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of BIRC5 protein17484886
D000068579CelecoxibBIRC5 protein inhibits the reaction [Celecoxib results in increased activity of CASP3 protein]17466271
D000068579CelecoxibCelecoxib binds to BIRC5 promoter17466271
D000068579Celecoxib[Celecoxib binds to BIRC5 promoter] which results in decreased expression of BIRC5 mRNA17466271|1746627
D000068579CelecoxibCelecoxib results in decreased expression of BIRC5 mRNA17270149|1746627
D000068579CelecoxibCelecoxib results in decreased expression of BIRC5 protein16004971|1612321
D000068579CelecoxibCelecoxib results in increased expression of BIRC5 mRNA17342322
D000068579Celecoxib[Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of BIRC5 protein21268125
D000068579CelecoxibCelecoxib results in decreased expression of BIRC5 mRNA17717820
D002699ChlorambucilChlorambucil affects the expression of BIRC5 mRNA17476690
D002706ChlordanChlordan results in increased expression of BIRC5 mRNA20403969
D002738ChloroquineChloroquine promotes the reaction [sunitinib results in decreased expression of BIRC5 protein]24751611
D002746ChlorpromazineChlorpromazine analog results in decreased expression of BIRC5 mRNA15924885
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of BIRC5 mRNA27858113
C011585ciclopiroxciclopirox results in decreased expression of BIRC5 mRNA19589922
C011585ciclopiroxciclopirox results in decreased expression of BIRC5 protein19589922
C039671ciglitazoneciglitazone results in decreased expression of BIRC517940898
C002471cinobufagincinobufagin results in decreased expression of BIRC5 protein23164673
D003033Coal TarCoal Tar results in decreased expression of BIRC5 mRNA27858113
C018021cobaltous chloridecobaltous chloride results in decreased expression of BIRC5 mRNA19320972|1937684
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of BIRC5 mRNA20971185
C464760copper-1,10-phenanthroline"copper-1,10-phenanthroline results in decreased expression of BIRC5 protein"24638265
D019327Copper SulfateCopper Sulfate results in decreased expression of BIRC5 mRNA19549813
C113861corosolic acidcorosolic acid results in increased expression of BIRC5 protein28506699
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BIRC5 mRNA"19167446
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of BIRC5 mRNA19167446
D003375CoumestrolCoumestrol results in increased expression of BIRC5 mRNA19167446
C551994crizotinibcrizotinib results in decreased expression of BIRC5 protein22729845
C551994crizotinibMET gene mutant form promotes the reaction [crizotinib results in increased expression of BIRC5 protein]22729845
C551994crizotinibcrizotinib results in decreased expression of BIRC521716144
D003474Curcumin[arsenic trioxide co-treated with Curcumin] results in decreased expression of BIRC5 protein27430728
D003474CurcuminCurcumin analog results in decreased expression of BIRC5 mRNA17671737|2640932
D003474CurcuminCurcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein]24664296
D003474CurcuminCurcumin inhibits the reaction [Nicotine results in increased expression of BIRC5 protein]20727180
D003474CurcuminCurcumin inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]23452621
D003474CurcuminCurcumin results in decreased expression of BIRC5 mRNA17596214|1767173
D003474CurcuminCurcumin results in decreased expression of BIRC5 protein16023083|1859393
D003474Curcumin[Curcumin co-treated with gemcitabine] results in decreased expression of BIRC5 protein17440100
C038459curdlancurdlan results in decreased expression of BIRC5 mRNA23543010
D016572CyclosporineCyclosporine results in decreased expression of BIRC5 mRNA20106945|2163298
D016572CyclosporineCyclosporine results in decreased expression of BIRC5 mRNA17942131
C463260D-65476FLT3 gene mutant form promotes the reaction [[D-65476 co-treated with Tretinoin] results in decreased expression of BIRC5 mRNA]16473406
C463260D-65476FLT3 gene mutant form promotes the reaction [[D-65476 co-treated with Tretinoin] results in decreased expression of BIRC5 protein]16473406
D003606DacarbazineDacarbazine results in increased expression of BIRC5 protein15577328
C531198dactolisibdactolisib results in decreased expression of BIRC5 protein22729845
C004315danthrondanthron results in decreased expression of BIRC5 protein21126053
D000069439DasatinibDasatinib results in decreased expression of BIRC5 mRNA20579391
D003630Daunorubicin[bromotetrandrine co-treated with Daunorubicin] results in decreased expression of BIRC5 mRNA21362215
D003630Daunorubicin[bromotetrandrine co-treated with Daunorubicin] results in decreased expression of BIRC5 protein21362215
D003630DaunorubicinDaunorubicin affects the expression of BIRC5 mRNA16638212
D003630Daunorubicin[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of BIRC5 mRNA21720514
D003630Daunorubicin[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of BIRC5 protein21720514
D003630Daunorubicin[Daunorubicin co-treated with bromotetrandrine] results in decreased expression of BIRC5 mRNA21720514
D003630Daunorubicin[Daunorubicin co-treated with bromotetrandrine] results in decreased expression of BIRC5 protein21720514
D003630DaunorubicinDaunorubicin results in increased expression of BIRC5 mRNA27780733
D003630DaunorubicinDaunorubicin results in increased expression of BIRC5 protein16638212
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of BIRC5 mRNA26206603
C014347decitabinedecitabine affects the expression of BIRC5 protein18636160
C014347decitabinedecitabine inhibits the reaction [trichostatin A results in decreased expression of BIRC5 mRNA]18718068
C014347decitabinedecitabine results in decreased expression of BIRC5 mRNA19363521
C014347decitabinedecitabine results in decreased expression of BIRC5 protein19363521
C014347decitabinedecitabine results in decreased methylation of BIRC5 promoter19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of BIRC5 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of BIRC5 protein]19363521
C107676deguelindeguelin inhibits the reaction [docetaxel results in increased expression of BIRC5 protein]17035597
C107676deguelindeguelin inhibits the reaction [Doxorubicin results in increased expression of BIRC5 protein]17035597
C107676deguelindeguelin results in decreased expression of BIRC5 protein17035597|1859336
C464444dehydroxymethylepoxyquinomicin[dehydroxymethylepoxyquinomicin co-treated with TNF protein] results in decreased expression of BIRC516211219
D013759DronabinolCDK1 inhibits the reaction [Dronabinol results in decreased expression of BIRC5 protein]16818634
D013759DronabinolDronabinol results in decreased expression of BIRC5 protein16818634
C040424destruxin Bdestruxin B results in decreased expression of BIRC5 protein22465936|2443401
D003907DexamethasoneDexamethasone affects the expression of BIRC521244764
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of BIRC5 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of BIRC5 mRNA28628672
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone results in increased expression of BIRC5]21244764
D003907Dexamethasone[PDCD5 protein co-treated with Dexamethasone] results in decreased expression of BIRC520693715
D016264Dextran SulfateAspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
D016264Dextran Sulfate[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein25449198
D016264Dextran SulfateCamptothecin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
D016264Dextran SulfatePlant Extracts inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
C028009diallyl disulfidediallyl disulfide results in decreased expression of BIRC5 protein17647244
C042577diallyl trisulfidediallyl trisulfide results in decreased expression of BIRC5 protein23754639
C042577diallyl trisulfidediallyl trisulfide results in increased expression of BIRC5 mRNA21411500
C042577diallyl trisulfidediallyl trisulfide results in increased expression of BIRC5 protein21411500
C042577diallyl trisulfidediallyl trisulfide results in increased expression of BIRC5 protein21411500
C038867diazenediazene analog affects the expression of BIRC516061352
D003976DiazinonDiazinon results in decreased expression of BIRC5 mRNA27920530
D003976DiazinonMagnesium Oxide analog inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]27920530
D003976Diazinon[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]27920530
D003976DiazinonSelenium analog inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]27920530
D003976DiazinonDiazinon affects the expression of BIRC5 mRNA22546817
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in decreased expression of BIRC5 mRNA"26496743
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of BIRC5 mRNA28973377
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of BIRC5 mRNA17361019
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of BIRC5 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of BIRC5 mRNA17379624
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of BIRC5 mRNA28962523
D002945CisplatinBIRC5 protein results in decreased susceptibility to Cisplatin11911975|1465491
D002945CisplatinBIRC5 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]15917659|1638289
D002945Cisplatin[Cisplatin co-treated with fisetin] results in decreased expression of BIRC5 protein21216935
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of BIRC5 mRNA27392435
D002945Cisplatin[Cisplatin co-treated with Quercetin] results in decreased expression of BIRC5 protein16082193
D002945CisplatinCisplatin inhibits the reaction [Piroxicam results in increased expression of BIRC5 mRNA]21858171
D002945CisplatinCisplatin results in decreased expression of BIRC5 mRNA11911975|1597070
D002945CisplatinCisplatin results in decreased expression of BIRC5 protein20674069
D002945CisplatinCisplatin results in increased expression of and results in increased phosphorylation of BIRC5 protein15981204
D002945CisplatinCisplatin results in increased expression of BIRC5 mRNA15981204|2116558
D002945CisplatinCisplatin results in increased expression of BIRC5 protein14988404|1739994
D002945CisplatinNoscapine promotes the reaction [Cisplatin results in decreased expression of BIRC5 protein]20674069
D002945CisplatinProadifen inhibits the reaction [Cisplatin results in increased expression of BIRC5 protein]26721606
D002945Cisplatintanshinone inhibits the reaction [Cisplatin results in increased expression of BIRC5 mRNA]21165580
D002945Cisplatin[TNFSF10 protein co-treated with Cisplatin] results in decreased expression of BIRC5 protein21252285
D002945CisplatinCisplatin results in increased expression of BIRC5 mRNA21151649
D002945Cisplatin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cisplatin results in increased expression of BIRC5 mRNA]20514400
D002945CisplatinCisplatin results in increased expression of BIRC5 mRNA20514400
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of BIRC5 mRNA26924002
D004026DieldrinDieldrin affects the expression of BIRC5 mRNA22546817
D004041Dietary FatsDietary Fats results in increased expression of BIRC5 mRNA25016146
D004052DiethylnitrosamineDiethylnitrosamine affects the localization of and results in increased expression of BIRC5 protein21776270
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of BIRC5 mRNA24535843
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of BIRC5 mRNA17854601
D004052DiethylnitrosamineRB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BIRC5 mRNA]17854601
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BIRC5 mRNA18164116
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of BIRC5 mRNA20514400
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of BIRC5 protein20514400
D004074DigitoxinDigitoxin analog results in decreased expression of BIRC5 protein22037315
D004074DigitoxinDigitoxin results in decreased expression of BIRC5 protein22037315
D002117CalcitriolCalcitriol promotes the reaction [Testosterone results in increased expression of BIRC5 mRNA]21592394
D002117CalcitriolCalcitriol results in decreased expression of BIRC5 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of BIRC5 mRNA21592394
D002117CalcitriolTestosterone promotes the reaction [Calcitriol results in increased expression of BIRC5 mRNA]21592394
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of BIRC5 mRNA"22044346
D0151279,10-Dimethyl-1,2-benzanthracene"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BIRC5 mRNA]"22044346
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of BIRC5 protein"18791811
D0151279,10-Dimethyl-1,2-benzanthracene"resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BIRC5 protein]"18791811
C067311docetaxelBIRC5 protein results in decreased susceptibility to docetaxel16224667|1910293
C067311docetaxeldeguelin inhibits the reaction [docetaxel results in increased expression of BIRC5 protein]17035597
C067311docetaxeldocetaxel results in increased expression of BIRC5 protein17035597
D004317Doxorubicinalvocidib inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of BIRC5 protein]12517802
D004317Doxorubicin[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BIRC5 mRNA24738333
D004317Doxorubicin[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BIRC5 protein24738333
D004317DoxorubicinBIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Doxorubicin]19211844
D004317DoxorubicinBIRC5 protein results in decreased susceptibility to Doxorubicin11911975|1608687
D004317Doxorubicindeguelin inhibits the reaction [Doxorubicin results in increased expression of BIRC5 protein]17035597
D004317DoxorubicinDoxorubicin promotes the reaction [DNMT1 protein binds to BIRC5 promoter]17124180
D004317DoxorubicinDoxorubicin promotes the reaction [EHMT2 protein binds to BIRC5 promoter]17124180
D004317DoxorubicinDoxorubicin promotes the reaction [HDAC1 protein binds to BIRC5 promoter]17124180
D004317DoxorubicinDoxorubicin promotes the reaction [SP1 protein binds to BIRC5 promoter]17124180
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to BIRC5 promoter]17124180
D004317DoxorubicinDoxorubicin results in decreased expression of BIRC5 mRNA11911975|1610801
D004317DoxorubicinDoxorubicin results in decreased expression of BIRC5 promoter12517802
D004317DoxorubicinDoxorubicin results in decreased expression of BIRC5 protein16108013|1936352
D004317DoxorubicinDoxorubicin results in increased expression of and results in increased phosphorylation of BIRC5 protein12517802
D004317DoxorubicinDoxorubicin results in increased expression of BIRC5 mRNA16086872|1752162
D004317DoxorubicinDoxorubicin results in increased expression of BIRC5 protein16086872|1703559
D004317Doxorubicin[FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Doxorubicin19211844
D004317Doxorubicin[gambogic acid co-treated with Doxorubicin] affects the expression of BIRC5 protein25824409
D004317DoxorubicinSB 203580 affects the reaction [[gambogic acid co-treated with Doxorubicin] affects the expression of BIRC5 protein]25824409
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin results in decreased expression of BIRC5 protein]19363521
D004365Drugs, Chinese Herbal"arsenic trioxide promotes the reaction [Drugs, Chinese Herbal results in decreased expression of BIRC5 protein]"28587418
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]"28587418
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of BIRC5 protein"28587418
C479799(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in decreased expression of BIRC5 mRNA15528975
C413879EKB 569EKB 569 results in decreased expression of BIRC5 mRNA22242139
C413879EKB 569EKB 569 results in decreased expression of BIRC5 protein22242139
D004642EmodinEmodin results in decreased expression of BIRC5 mRNA23848338
D004642EmodinEmodin results in decreased expression of BIRC5 protein23848338
D004726EndosulfanEndosulfan results in decreased expression of BIRC5 mRNA26714676
D015251EpirubicinBIRC5 protein results in decreased susceptibility to Epirubicin16188142
C045651epigallocatechin gallate[epigallocatechin gallate co-treated with leptomycin B] results in decreased expression of BIRC5 mRNA25922640
C045651epigallocatechin gallate[epigallocatechin gallate co-treated with leptomycin B] results in decreased expression of BIRC5 protein25922640
C078846epoxomicinepoxomicin inhibits the reaction [Aspirin results in decreased expression of BIRC5 protein]18483385
C078846epoxomicinepoxomicin results in increased expression of BIRC5 protein17510429
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride promotes the reaction [resveratrol results in decreased expression of BIRC5 protein]25895606
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride results in decreased expression of BIRC5 protein25895606
D000069347Erlotinib Hydrochlorideresveratrol promotes the reaction [Erlotinib Hydrochloride results in decreased expression of BIRC5 protein]25895606
D004976Ethacrynic Acid[arsenic trioxide co-treated with Ethacrynic Acid] results in decreased expression of BIRC5 protein23082001
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of BIRC5 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of BIRC5 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BIRC5 mRNA17942748
D017308EtodolacEtodolac results in decreased expression of BIRC5 protein16004971|1610487
D017308EtodolacEtodolac results in increased activity of BIRC5 protein16046235
D017308Etodolac[oxaliplatin co-treated with Etodolac] results in decreased expression of BIRC5 protein16004971
D005047EtoposideBIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]19211844
D005047EtoposideBIRC5 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]15917659|1638289
D005047EtoposideBIRC5 protein results in decreased susceptibility to Etoposide16322251|1636492
D005047EtoposideEstradiol inhibits the reaction [Etoposide results in increased expression of BIRC5 mRNA]19426747
D005047EtoposideEtoposide results in increased expression of BIRC5 mRNA19426747
D005047Etoposide[FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide19211844
D000068338EverolimusEverolimus promotes the reaction [platycodin D results in decreased expression of BIRC5 protein]28711525
D000068338EverolimusEverolimus results in decreased expression of BIRC5 protein21601561|2871152
D000068338Everolimusnavitoclax promotes the reaction [Everolimus results in decreased expression of BIRC5 protein]28947240
D000068338Everolimusplatycodin D promotes the reaction [Everolimus results in decreased expression of BIRC5 protein]28711525
C049639evodiamineevodiamine inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]15710601
D015025ZearalenoneZearalenone results in increased expression of BIRC5 mRNA28965971
C060802fangchinolinefangchinoline results in decreased expression of BIRC5 mRNA28754437
C060802fangchinolinefangchinoline results in decreased expression of BIRC5 protein28754437
C004808farnesyl pyrophosphatefarnesyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein]17472962
C093323farnesylthiosalicylic acidfarnesylthiosalicylic acid results in decreased expression of BIRC5 protein16780807
C017875fisetin[Cisplatin co-treated with fisetin] results in decreased expression of BIRC5 protein21216935
C548902FLLL 32FLLL 32 results in decreased expression of BIRC5 mRNA21109950
C548902FLLL 32FLLL 32 results in decreased expression of BIRC5 protein20576164|2110995
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of BIRC5 mRNA19167416|2221319
D005459Fluorides[Arsenic co-treated with Fluorides] results in increased expression of BIRC5 mRNA19962721
D005459FluoridesFluorides results in increased expression of BIRC5 mRNA19962721
D005472FluorouracilBIRC5 affects the susceptibility to Fluorouracil15067352
D005472FluorouracilBIRC5 protein affects the susceptibility to Fluorouracil16217747|1871415
D005472FluorouracilBIRC5 protein results in decreased susceptibility to Fluorouracil15685548
D005472FluorouracilBIRC5 results in decreased susceptibility to Fluorouracil16546719|1961860
D005472Fluorouracil[Fluorouracil co-treated with RNF34 protein] results in increased expression of BIRC5 protein16596200
D005472FluorouracilFluorouracil results in decreased expression of BIRC5 mRNA16709241|1692916
D005472FluorouracilFluorouracil results in decreased expression of BIRC5 protein16929163|1739994
D005472FluorouracilFluorouracil results in increased expression of BIRC5 mRNA15109396|2859947
D005472FluorouracilFluorouracil results in increased expression of BIRC5 protein17399942
D005472Fluorouracilgemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 mRNA]16929163
D005472Fluorouracilgemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 protein]16929163
D005472Fluorouracil[SM-1 compound co-treated with Fluorouracil] results in decreased expression of BIRC5 mRNA28599477
D005472FluorouracilSM-1 compound inhibits the reaction [Fluorouracil results in increased expression of BIRC5 mRNA]28599477
D005472FluorouracilSM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BIRC5 protein]28599477
D005480FlurbiprofenFlurbiprofen results in increased expression of BIRC5 mRNA16949054
C007789fucoidanfucoidan results in decreased expression of BIRC5 protein16201850
C070081fulvestrant[fulvestrant co-treated with Sirolimus] results in decreased expression of BIRC5 mRNA19016759
C070081fulvestrantfulvestrant results in decreased expression of BIRC5 mRNA19016759
C070081fulvestrantfulvestrant results in decreased expression of BIRC5 mRNA21980073
C039281furan[Bromodeoxyuridine co-treated with furan] results in increased expression of BIRC5 mRNA24910943
C039281furanfuran results in increased expression of BIRC5 mRNA24183702|2491094
C039281furanfuran results in increased expression of BIRC5 mRNA22079235|2553966
D005665FurosemideFurosemide affects the expression of BIRC5 mRNA17497460
C052659gambogic acidgambogic acid affects the expression of BIRC5 protein25824409
C052659gambogic acid[gambogic acid co-treated with Doxorubicin] affects the expression of BIRC5 protein25824409
C052659gambogic acidSB 203580 affects the reaction [[gambogic acid co-treated with Doxorubicin] affects the expression of BIRC5 protein]25824409
C106014geduningedunin results in decreased expression of BIRC5 mRNA17010675
C419708gefitinibgefitinib results in decreased expression of BIRC5 protein28942004
C419708gefitinibgefitinib results in increased expression of BIRC5 protein17473213
C419708gefitinibleptomycin B promotes the reaction [gefitinib results in decreased expression of BIRC5 protein]28942004
C419708gefitinibtyrphostin AG 1024 inhibits the reaction [gefitinib results in increased expression of BIRC5 protein]17473213
C056507gemcitabinegemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 mRNA]16929163
C056507gemcitabinegemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 protein]16929163
C056507gemcitabine[Curcumin co-treated with gemcitabine] results in decreased expression of BIRC5 protein17440100
D019833GenisteinGenistein inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]23452621
D019833GenisteinGenistein results in decreased expression of BIRC5 mRNA16705744
D019833GenisteinGenistein results in increased expression of BIRC5 mRNA16474171
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein]17472962
C007845gingerolAcetylcysteine inhibits the reaction [gingerol results in decreased expression of BIRC5 protein]25034532
C007845gingerolgingerol inhibits the reaction [Testosterone results in increased expression of BIRC5 protein]18030663
C007845gingerolgingerol results in decreased expression of BIRC5 protein18030663|2503453
C007845gingerolgingerol inhibits the reaction [Testosterone results in increased expression of BIRC5 protein]18030663
C097367ginsenoside Rg3ginsenoside Rg3 results in decreased expression of BIRC5 mRNA19778801
C097367ginsenoside Rg3ginsenoside Rg3 results in decreased expression of BIRC5 protein19778801
C086854glycine-extended gastrin 17glycine-extended gastrin 17 results in increased expression of BIRC5 mRNA19153190
C086854glycine-extended gastrin 17glycine-extended gastrin 17 results in increased expression of BIRC5 protein19153190
C086854glycine-extended gastrin 17STAT3 protein affects the reaction [glycine-extended gastrin 17 results in increased expression of BIRC5 protein]19153190
C086854glycine-extended gastrin 17stattic inhibits the reaction [glycine-extended gastrin 17 results in increased expression of BIRC5 mRNA]19153190
D005999Glycochenodeoxycholic AcidGlycochenodeoxycholic Acid results in increased expression of BIRC5 mRNA15767249
C568713GSK1210151AGSK1210151A results in decreased expression of BIRC5 mRNA26877780
C568713GSK1210151AGSK1210151A results in decreased expression of BIRC5 protein26877780
D018738HexamethoniumHexamethonium affects the reaction [Nicotine results in increased expression of BIRC5 protein]16601104
D017313FenretinideFenretinide results in increased expression of BIRC5 mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of BIRC5 mRNA20044591|2651922
D006877Hydroxamic AcidsHydroxamic Acids analog results in decreased expression of BIRC5 protein26088127
C021304hyperoside[Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 mRNA24173369
C021304hyperoside[Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 protein24173369
D000068877Imatinib MesylateBIRC5 protein results in decreased susceptibility to Imatinib Mesylate16166298|1625414
D000068877Imatinib MesylateImatinib Mesylate results in decreased expression of BIRC5 protein16254145
C016517indole-3-carbinolindole-3-carbinol inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]15811958
C016517indole-3-carbinolindole-3-carbinol results in decreased expression of BIRC516082211
D007213IndomethacinIndomethacin results in decreased expression of BIRC5 mRNA15248904|1727014
D007213IndomethacinIndomethacin results in decreased expression of BIRC5 protein17270149
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of BIRC5 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of BIRC5 mRNA28628672
D007213Indomethacinbutaprost inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased expression of BIRC5 protein]21268125
D007213IndomethacinDinoprostone inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased expression of BIRC5 protein]21268125
D007213Indomethacin[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased expression of BIRC5 protein21268125
D007213IndomethacinIndomethacin results in decreased expression of BIRC5 protein17654042
D007213IndomethacinTXN protein inhibits the reaction [Indomethacin results in decreased expression of BIRC5 protein]17654042
C051890irinotecan[irinotecan co-treated with Bortezomib] results in decreased expression of BIRC5 protein16373703
C051890irinotecanirinotecan metabolite results in decreased expression of BIRC5 mRNA15956246
C051890irinotecanirinotecan promotes the reaction [AS602868 results in decreased expression of BIRC5 mRNA]18182997
C051890irinotecanirinotecan results in decreased expression of BIRC5 mRNA15956246
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of BIRC5 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of BIRC5 mRNA28628672
D007530IsofluraneIsoflurane results in decreased expression of BIRC5 mRNA16978161
C055785jatrorrhizinejatrorrhizine binds to BIRC5 promoter17968851
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of BIRC5 mRNA27392435
C544151jinfukangjinfukang results in increased expression of BIRC5 mRNA27392435
C561695(+)-JQ1 compoundAnisomycin promotes the reaction [(+)-JQ1 compound results in decreased expression of BIRC5 protein]23872705
C561695(+)-JQ1 compoundbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound results in decreased expression of BIRC5 protein]23872705
C561695(+)-JQ1 compound(+)-JQ1 compound affects the expression of BIRC5 mRNA26397223
C561695(+)-JQ1 compound[(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of BIRC5 mRNA27169980
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of BIRC5 mRNA23430699|2596192
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of BIRC5 protein23872705|2687778
C410337K 7174K 7174 results in decreased expression of BIRC5 mRNA24086573
C510621KCC 009KCC 009 results in decreased expression of BIRC5 protein16170020
C572783kuguacin Jkuguacin J results in decreased expression of BIRC5 protein22266361
C490728lapatiniblapatinib results in decreased expression of BIRC5 protein16091755
D007840LatexLatex analog results in increased expression of BIRC5 mRNA24768652
C045463leflunomideleflunomide results in decreased expression of BIRC5 mRNA28988120
C038753leptomycin B[epigallocatechin gallate co-treated with leptomycin B] results in decreased expression of BIRC5 mRNA25922640
C038753leptomycin B[epigallocatechin gallate co-treated with leptomycin B] results in decreased expression of BIRC5 protein25922640
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in increased expression of BIRC5 mRNA20803015
C038753leptomycin Bleptomycin B promotes the reaction [gefitinib results in decreased expression of BIRC5 protein]28942004
C038753leptomycin Bleptomycin B results in decreased expression of BIRC5 mRNA20803015|2592264
C038753leptomycin Bleptomycin B results in decreased expression of BIRC5 protein20803015|2592264
C038753leptomycin BTP53 gene mutant form inhibits the reaction [leptomycin B results in decreased expression of BIRC5 protein]20803015
C541528licochalcone Blicochalcone B results in decreased expression of BIRC5 protein24384411
D008094LithiumLithium results in increased expression of BIRC5 mRNA16288908
D018021Lithium ChlorideLithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA]24464479
C549232LLL12 compoundLLL12 compound results in decreased expression of BIRC5 mRNA21109950
C549232LLL12 compoundLLL12 compound results in decreased expression of BIRC5 protein21109950
C115354lonafarniblonafarnib inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]15090542
D008148Lovastatinfarnesyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein]17472962
D008148Lovastatingeranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein]17472962
D008148LovastatinLovastatin results in decreased expression of BIRC5 protein17472962|1881588
D008154LucanthoneLucanthone results in decreased expression of BIRC5 mRNA21148553
D008277Magnesium OxideMagnesium Oxide analog inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]27920530
D008277Magnesium Oxide[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]27920530
D058185Magnetite Nanoparticles[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BIRC5 mRNA24738333
D058185Magnetite Nanoparticles[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of BIRC5 protein24738333
D058185Magnetite Nanoparticles[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of BIRC5 mRNA21720514
D058185Magnetite Nanoparticles[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of BIRC5 protein21720514
C025340manganese chlorideLithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA]24464479
C025340manganese chloridemanganese chloride results in decreased expression of BIRC5 mRNA24464479
C013592mangiferinmangiferin results in decreased expression of BIRC5 protein26996543
C034244matrinearsenic trioxide promotes the reaction [matrine results in decreased expression of BIRC5 protein]23700110
C034244matrinematrine promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]23700110
C034244matrinematrine results in decreased expression of BIRC5 protein23700110
C540278MDV 3100MDV 3100 promotes the reaction [Niclosamide results in decreased expression of BIRC5 protein]25970160
D008558MelphalanBIRC5 protein affects the susceptibility to Melphalan16373717
D008558MelphalanNocodazole affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]16373717
D008558MelphalanPaclitaxel affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]16373717
D008694MethamphetamineMethamphetamine results in decreased expression of BIRC5 mRNA25290377
D008713MethimazoleMethimazole results in decreased expression of BIRC5 mRNA17403546
D008730MethoxsalenBHLHE40 protein inhibits the reaction [Methoxsalen results in decreased expression of BIRC5 protein]22796345
D008730MethoxsalenMethoxsalen results in decreased expression of BIRC5 protein22796345
C005219methyl cellosolvemethyl cellosolve results in decreased expression of BIRC5 mRNA19643169
D008748MethylcholanthreneMethylcholanthrene results in increased expression of BIRC5 mRNA20713471
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of BIRC5 mRNA19465457
C030589methylmercury cysteinemethylmercury cysteine results in decreased expression of BIRC5 mRNA19465457
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of BIRC5 mRNA25270620
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of BIRC5 mRNA24810058
C008493methylselenic acid"[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of BIRC5 protein"18444175
C008493methylselenic acidmethylselenic acid inhibits the reaction [SP1 protein binds to BIRC5 promoter]17876054
C008493methylselenic acidmethylselenic acid results in decreased expression of BIRC5 mRNA12517777|1787605
C008493methylselenic acidmethylselenic acid results in decreased expression of BIRC5 protein17876054|1844417
D008777MethyltestosteroneMethyltestosterone results in decreased expression of BIRC5 mRNA29191790
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone results in increased expression of BIRC5]21244764
C066851mithramycin Amithramycin A results in decreased expression of BIRC5 mRNA17124180
D016685MitomycinMitomycin results in increased expression of BIRC5 mRNA18250050
D016685MitomycinMitomycin results in increased expression of BIRC5 protein18250050
D008942MitoxantroneMitoxantrone affects the expression of BIRC5 mRNA16638212
D008942MitoxantroneMitoxantrone results in increased expression of BIRC5 protein16638212
C070571ML 7ML 7 results in decreased expression of BIRC5 protein18710790
D016686MonocrotalineMonocrotaline results in increased expression of BIRC5 mRNA25460361
D016686MonocrotalineQuercetin inhibits the reaction [Monocrotaline results in increased expression of BIRC5 mRNA]25460361
C008542monodansylcadaverinemonodansylcadaverine results in decreased expression of BIRC5 protein16170020
C517284monomethyl phthalatemonomethyl phthalate affects the expression of BIRC5 mRNA26924002
C008548morinmorin results in decreased expression of BIRC5 mRNA28689916
C437683motexafin gadoliniummotexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of BIRC5 mRNA]16357179
C437683motexafin gadoliniummotexafin gadolinium results in increased expression of BIRC5 mRNA16357179
D009151Mustard GasMustard Gas results in decreased expression of BIRC5 mRNA25102026
C455139myrtucommulone Amyrtucommulone A results in decreased expression of BIRC5 mRNA26032814
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of BIRC5 mRNA"29244179
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]18377872
C550356N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide"(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol inhibits the reaction [N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide results in increased expression of and affects the localization of BIRC5 protein]"24444656
C550356N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide"N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide results in increased expression of and affects the localization of BIRC5 protein"24444656
C550356N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide"[N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide results in increased expression of BIRC5 protein] which affects the susceptibility to YM 155"24444656
C550356N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide"Sirolimus inhibits the reaction [N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide results in increased expression of and affects the localization of BIRC5 protein]"24444656
C084956N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosineBIRC5 protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine16088125
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of BIRC5 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog affects the expression of BIRC5 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of BIRC5 mRNA"25620056
C000621033napabucasinnapabucasin results in decreased expression of BIRC5 mRNA26899963
C000621033napabucasinnapabucasin results in decreased expression of BIRC5 protein25605917|2689996
C031721naphthalenenaphthalene results in increased expression of BIRC5 mRNA18978301
C073873naphtho(1,2-b)furan-4,5-dione"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naphtho(1,2-b)furan-4,5-dione results in decreased expression of BIRC5 protein]"19747539
C073873naphtho(1,2-b)furan-4,5-dione"naphtho(1,2-b)furan-4,5-dione results in decreased expression of BIRC5 protein"19747539|2019708
C073873naphtho(1,2-b)furan-4,5-dione"pyrazolanthrone inhibits the reaction [naphtho(1,2-b)furan-4,5-dione results in decreased expression of BIRC5 protein]"19747539
C528561navitoclax[MTOR protein affects the susceptibility to navitoclax] which affects the expression of BIRC5 protein28947240
C528561navitoclaxnavitoclax promotes the reaction [Everolimus results in decreased expression of BIRC5 protein]28947240
C528561navitoclaxnavitoclax results in decreased expression of BIRC5 protein28947240
D009532NickelNickel results in increased expression of BIRC5 mRNA19031421|2558310
D009532Nickel[Quercetin analog co-treated with Nickel] results in decreased expression of BIRC5 protein20577783
C022838nickel chloridenickel chloride affects the expression of BIRC5 mRNA22546817
C550717nickel ferritenickel ferrite results in decreased expression of BIRC5 mRNA21382431
C029938nickel sulfatenickel sulfate affects the localization of and results in increased expression of BIRC5 protein21776270
D009534NiclosamideMDV 3100 promotes the reaction [Niclosamide results in decreased expression of BIRC5 protein]25970160
D009534NiclosamideNiclosamide affects the expression of BIRC5 protein24552774
D009534NiclosamideNiclosamide inhibits the reaction [IL6 protein results in increased expression of BIRC5 protein]25970160
D009534NiclosamideNiclosamide results in decreased expression of BIRC5 protein24736023|2597016
D009538NicotineCurcumin inhibits the reaction [Nicotine results in increased expression of BIRC5 protein]20727180
D009538NicotineHexamethonium affects the reaction [Nicotine results in increased expression of BIRC5 protein]16601104
D009538NicotineNicotine inhibits the reaction [RB1 protein binds to BIRC5 promoter]16601104
D009538NicotineNicotine promotes the reaction [E2F1 protein binds to BIRC5 promoter]16601104
D009538NicotineNicotine results in increased expression of BIRC5 mRNA16601104|1989649
D009538NicotineNicotine results in increased expression of BIRC5 protein16601104|2072718
C042198nimbolidenimbolide results in decreased expression of BIRC5 protein20429769
C012655nimesulidenimesulide results in decreased expression of BIRC5 protein16969492
D009569Nitric OxideNitric Oxide results in decreased expression of BIRC5 mRNA15126337
D009569Nitric OxideNitric Oxide results in decreased expression of BIRC5 protein16166326
D009599Nitroprusside4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Nitroprusside results in decreased expression of BIRC5 protein]14988404
D009599Nitroprusside6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine promotes the reaction [Nitroprusside results in decreased expression of BIRC5 mRNA]14988404
D009599NitroprussideNitroprusside results in decreased expression of BIRC5 mRNA14988404
D009599NitroprussideNitroprusside results in decreased expression of BIRC5 protein14988404
D009599NitroprussideNSC 663284 promotes the reaction [Nitroprusside results in decreased expression of BIRC5 mRNA]14988404
C047330N-methylisoindigotinN-methylisoindigotin results in decreased expression of BIRC5 protein26887594
D015739NocodazoleNocodazole affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]16373717
D009665NoscapineBIRC5 protein results in decreased susceptibility to Noscapine22848370
D009665NoscapineNoscapine promotes the reaction [Cisplatin results in decreased expression of BIRC5 protein]20674069
D009665NoscapineNoscapine results in decreased expression of BIRC5 protein20674069
D009665NoscapineNoscapine results in increased expression of BIRC5 mRNA22848370
D009665NoscapineNoscapine results in increased expression of BIRC5 protein22848370
C440614NSC 663284NSC 663284 promotes the reaction [Nitroprusside results in decreased expression of BIRC5 mRNA]14988404
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of BIRC5 mRNA20971185
C025589ochratoxin Aochratoxin A results in decreased expression of BIRC5 mRNA27193732
C025589ochratoxin Aochratoxin A results in increased expression of BIRC5 mRNA19237604|1956249
C025589ochratoxin Aochratoxin A results in increased expression of BIRC5 protein19237604
C016340o,p'-DDT"o,p'-DDT analog results in decreased expression of BIRC5 mRNA"22937105
C030110oxaliplatin4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [oxaliplatin results in decreased expression of BIRC5 protein]20708607
C030110oxaliplatinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to [oxaliplatin results in decreased expression of BIRC5 protein]20708607
C030110oxaliplatinBIRC5 protein results in decreased susceptibility to oxaliplatin20708607
C030110oxaliplatin[oxaliplatin co-treated with Etodolac] results in decreased expression of BIRC5 protein16004971
C030110oxaliplatinoxaliplatin results in decreased expression of BIRC5 mRNA20708607
C030110oxaliplatinoxaliplatin results in decreased expression of BIRC5 protein16004971|1602453
C030110oxaliplatinoxaliplatin results in increased expression of BIRC5 protein19147571
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of BIRC5 mRNA25729387
C030110oxaliplatinoxaliplatin results in decreased expression of BIRC5 mRNA25729387
C030110oxaliplatin4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole affects the reaction [BIRC5 protein results in decreased susceptibility to oxaliplatin]20708607
C552952oxazolinodaunorubicinoxazolinodaunorubicin affects the expression of BIRC5 mRNA27780733
D010100OxygenOxygen deficiency results in increased expression of BIRC5 mRNA22711276
D010100OxygenValproic Acid inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 mRNA]22711276
D010100Oxygenvorinostat inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 mRNA]22711276
D010100Oxygen"3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]"23452621
D010100Oxygen[arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of BIRC5 mRNA19825857
D010100Oxygen[arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of BIRC5 protein19825857
D010100Oxygenbetulin analog promotes the reaction [Oxygen deficiency results in decreased expression of BIRC5 protein]26540049
D010100Oxygenbetulinic acid promotes the reaction [Oxygen deficiency results in decreased expression of BIRC5 protein]26540049
D010100OxygenCurcumin inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]23452621
D010100OxygenGenistein inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]23452621
D010100OxygenHIF1A affects the reaction [Oxygen deficiency affects the expression of BIRC5 mRNA]16628086
D010100OxygenHIF1A affects the reaction [Oxygen deficiency affects the expression of BIRC5 protein]16628086
D010100OxygenITGB1 affects the reaction [Oxygen deficiency affects the expression of BIRC5 mRNA]16628086
D010100OxygenITGB1 affects the reaction [Oxygen deficiency affects the expression of BIRC5 protein]16628086
D010100OxygenOxygen deficiency results in decreased expression of BIRC5 protein26540049
D010100OxygenOxygen deficiency results in increased expression of BIRC5 mRNA23452621
D010100OxygenOxygen deficiency results in increased expression of BIRC5 protein23452621
D010100OxygenOxygen results in decreased expression of BIRC5 mRNA27103661
D010100OxygenPlant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]23452621
D010100Oxygenresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]23452621
D010126OzoneOzone results in increased expression of BIRC5 mRNA12763052|1955522
D010126OzoneTTPA protein affects the reaction [Ozone results in increased expression of BIRC5 mRNA]19555225
D017239Paclitaxel"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Paclitaxel results in increased expression of BIRC5]"16211241
D017239Paclitaxel"[4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide co-treated with Paclitaxel] results in decreased expression of BIRC5 protein"16170024
D017239PaclitaxelBIRC5 protein results in decreased susceptibility to Paclitaxel16202317
D017239PaclitaxelBIRC5 results in decreased susceptibility to Paclitaxel19133282
D017239PaclitaxelPaclitaxel affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]16373717
D017239PaclitaxelPaclitaxel results in decreased expression of BIRC5 mRNA15970709
D017239PaclitaxelPaclitaxel results in decreased expression of BIRC5 promoter12517802
D017239PaclitaxelPaclitaxel results in decreased expression of BIRC5 protein14749477|1739994
D017239PaclitaxelPaclitaxel results in increased expression of BIRC516211241
D017239PaclitaxelPaclitaxel results in increased expression of BIRC5 protein12517802|1739994
D017239PaclitaxelProdigiosin inhibits the reaction [Paclitaxel results in increased expression of BIRC5 protein]19133282
D017239Paclitaxel[Tretinoin co-treated with Paclitaxel] results in decreased expression of BIRC5 protein17701358|1809827
D017239Paclitaxelvorinostat inhibits the reaction [Paclitaxel results in increased expression of BIRC5 protein]19875160
C500026palbociclibpalbociclib results in decreased expression of BIRC5 mRNA22869556
C005413palmatinepalmatine binds to BIRC5 promoter17968851
D010269ParaquatParaquat results in increased expression of BIRC5 mRNA26345256
D010269ParaquatParaquat results in decreased expression of BIRC5 mRNA26887261
D052638Particulate Matter2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in decreased expression of BIRC5 mRNA]28655636
D052638Particulate MatterParticulate Matter results in decreased expression of BIRC5 mRNA28655636
C418868PBOX-6[alvocidib co-treated with PBOX-6] results in decreased expression of BIRC5 protein20206141
C418868PBOX-6BIRC5 results in decreased susceptibility to PBOX-620206141
C000610380p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane"p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane results in decreased expression of BIRC5 protein"26035713
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BIRC5 mRNA"25510870
C115711PD 173074[arsenic trioxide results in increased susceptibility to PD 173074] which results in decreased expression of BIRC5 protein27794399
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of BIRC5 mRNA23948077
C494474perchlorateperchlorate results in decreased expression of BIRC5 mRNA17403546
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid affects the expression of BIRC5 mRNA27018151
C023036perfluorooctanoic acidNR1H3 protein affects the reaction [perfluorooctanoic acid results in increased expression of BIRC5 mRNA]25949234
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of BIRC5 mRNA25949234
D015232DinoprostoneDinoprostone inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased expression of BIRC5 protein]21268125
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of BIRC5 mRNA24535843
D010634PhenobarbitalPhenobarbital results in increased expression of BIRC5 mRNA19363144|2040396
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BIRC5 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of BIRC5 mRNA26272509
D048789PhytoestrogensPhytoestrogens results in increased expression of BIRC5 mRNA18310284
C415032picropodophyllinpicropodophyllin results in decreased expression of BIRC5 protein16166596
C121565pifithrinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of BIRC5 protein]19812371
C121565pifithrin[Topotecan co-treated with pifithrin] results in increased degradation of BIRC5 protein19812371
C049032pinosylvin[pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BIRC5 mRNA23333577
C006253pirinixic acidpirinixic acid results in increased expression of BIRC5 mRNA18301758|2381119
D010894PiroxicamCisplatin inhibits the reaction [Piroxicam results in increased expression of BIRC5 mRNA]21858171
D010894PiroxicamPiroxicam results in increased expression of BIRC5 mRNA21858171
D010936Plant ExtractsPlant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]23452621
D010936Plant ExtractsPlant Extracts inhibits the reaction [TNFSF10 protein results in decreased expression of BIRC5 protein]20971099
D010936Plant ExtractsPlant Extracts results in decreased expression of BIRC5 mRNA23557933
D010936Plant ExtractsPlant Extracts results in decreased expression of BIRC5 protein24021570|2544919
D010936Plant ExtractsPlant Extracts inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]25449198
D010936Plant ExtractsPlant Extracts results in decreased expression of BIRC5 mRNA20653974
D010936Plant ExtractsPlant Extracts results in decreased expression of BIRC5 protein20653974
C013649plastochromanol 8plastochromanol 8 results in decreased expression of BIRC5 mRNA23941772
C108953platycodin DEverolimus promotes the reaction [platycodin D results in decreased expression of BIRC5 protein]28711525
C108953platycodin Dplatycodin D promotes the reaction [Everolimus results in decreased expression of BIRC5 protein]28711525
C108953platycodin Dplatycodin D results in decreased expression of BIRC5 protein28711525
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls analog results in increased expression of BIRC5 mRNA16474171
D011070Poly I-CPoly I-C promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]21418039
D059808PolyphenolsPolyphenols results in decreased expression of BIRC5 protein24021570
C556217polyphyllin Ipolyphyllin I results in decreased expression of BIRC5 protein26821882
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione inhibits the reaction [TNF protein results in increased expression of BIRC5 mRNA]"15322087
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of BIRC5 mRNA22698814|2890350
D011335ProadifenProadifen inhibits the reaction [Cisplatin results in increased expression of BIRC5 protein]26721606
D011353ProdigiosinBIRC5 results in decreased susceptibility to Prodigiosin19133282
D011353ProdigiosinProdigiosin inhibits the reaction [Paclitaxel results in increased expression of BIRC5 protein]19133282
D011353ProdigiosinProdigiosin results in decreased expression of BIRC5 mRNA19133282
D011353ProdigiosinProdigiosin results in decreased expression of BIRC5 protein19133282
D011374ProgesteroneProgesterone results in decreased expression of BIRC5 mRNA23012394|2301818
D011374ProgesteroneProgesterone results in decreased expression of BIRC5 mRNA21795739
D011374ProgesteroneProgesterone results in increased expression of BIRC5 mRNA21549006
C045950propiconazolepropiconazole results in increased expression of BIRC5 mRNA21278054|2594923
C005556propionaldehydepropionaldehyde results in decreased expression of BIRC5 mRNA26079696
D011429Propolis[Butylhydroxybutylnitrosamine co-treated with Propolis analog] results in increased expression of BIRC5 mRNA26111810
D011441PropylthiouracilPropylthiouracil results in increased expression of BIRC5 mRNA24780913
D011441PropylthiouracilPropylthiouracil results in decreased expression of BIRC5 mRNA17403546
C033607puerarinarsenic trioxide promotes the reaction [puerarin results in decreased expression of BIRC5 mRNA]20416161
C033607puerarinpuerarin results in decreased expression of BIRC5 mRNA20416161
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of BIRC5 mRNA19617259
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of BIRC5 protein19617259
C572726pycnidionepycnidione results in decreased expression of BIRC5 protein22450442
C513428pyrachlostrobinpyrachlostrobin results in increased expression of BIRC5 mRNA27029645
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]16328441|2159458
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [naphtho(1,2-b)furan-4,5-dione results in decreased expression of BIRC5 protein]"19747539
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [sodium arsenite results in decreased expression of BIRC5 mRNA]22706169
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [sodium arsenite results in decreased expression of BIRC5 protein]22706169
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of BIRC5 mRNA"21152443
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of BIRC5 mRNA"21152443
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BIRC5 mRNA]21161674
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 mRNA]16139439
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 protein]16139439
D011794Quercetin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]18377872
D011794Quercetinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]17548900
D011794Quercetin[Cisplatin co-treated with Quercetin] results in decreased expression of BIRC5 protein16082193
D011794QuercetinN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]18377872
D011794Quercetin[Quercetin analog co-treated with Nickel] results in decreased expression of BIRC5 protein20577783
D011794Quercetin[Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 mRNA24173369
D011794Quercetin[Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 protein24173369
D011794QuercetinQuercetin inhibits the reaction [SP1 protein binds to BIRC5 promoter]18377872
D011794QuercetinQuercetin inhibits the reaction [TNFSF10 protein results in increased expression of BIRC5 protein]21933852
D011794QuercetinQuercetin results in decreased expression of BIRC5 mRNA19440933|2193385
D011794QuercetinQuercetin results in decreased expression of BIRC5 protein16082193|1754890
D011794QuercetinQuercetin results in increased expression of BIRC5 protein14988404
D011794Quercetin[resveratrol co-treated with Quercetin] results in decreased expression of BIRC5 mRNA23530649
D011794Quercetin[resveratrol co-treated with Quercetin] results in decreased expression of BIRC5 protein23530649
D011794Quercetin"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BIRC5 mRNA]"22044346
D011794QuercetinQuercetin inhibits the reaction [Monocrotaline results in increased expression of BIRC5 mRNA]25460361
C523166quercetin 3-O-beta-(2''-galloyl)-rhamnopyranosidequercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [TNFSF10 protein results in decreased expression of BIRC5 protein]23711929
D017382Reactive Oxygen Species[Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of BIRC5 protein17136320
C052785rebamipiderebamipide results in decreased expression of BIRC5 mRNA15993841
C052785rebamipiderebamipide results in decreased expression of BIRC5 protein15993841
D012110ReserpineReserpine binds to BIRC5 promoter17968851
D012116Resins, Plant"Resins, Plant results in decreased expression of BIRC5 protein"27268964
C059514resveratrol"[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of BIRC5 protein"18444175
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of BIRC5 mRNA19167446
C059514resveratrolErlotinib Hydrochloride promotes the reaction [resveratrol results in decreased expression of BIRC5 protein]25895606
C059514resveratrolpyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BIRC5 mRNA]21161674
C059514resveratrol[resveratrol co-treated with Quercetin] results in decreased expression of BIRC5 mRNA23530649
C059514resveratrol[resveratrol co-treated with Quercetin] results in decreased expression of BIRC5 protein23530649
C059514resveratrol[resveratrol co-treated with sorafenib] results in decreased expression of BIRC5 protein26911335
C059514resveratrolresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]23452621
C059514resveratrolresveratrol promotes the reaction [Erlotinib Hydrochloride results in decreased expression of BIRC5 protein]25895606
C059514resveratrolresveratrol results in decreased expression of BIRC5 mRNA17261084|1727014
C059514resveratrolresveratrol results in decreased expression of BIRC5 protein15763656|1700701
C059514resveratrolresveratrol results in increased expression of BIRC5 mRNA21161674
C059514resveratrolBIRC5 protein affects the reaction [resveratrol results in increased cleavage of CASP3 protein]22137261
C059514resveratrolBIRC5 protein affects the reaction [resveratrol results in increased cleavage of CASP9 protein]22137261
C059514resveratrol"resveratrol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BIRC5 protein]"18791811
C059514resveratrolresveratrol results in decreased expression of and results in decreased phosphorylation of BIRC5 protein15837718
C059514resveratrolresveratrol results in decreased expression of BIRC5 mRNA15837718
C059514resveratrolresveratrol results in decreased expression of BIRC5 protein22137261|2550515
C059514resveratrolresveratrol results in increased expression of BIRC5 mRNA16081268
C059514resveratrolSIRT1 protein affects the reaction [resveratrol results in decreased expression of BIRC5 protein]22137261
C059514resveratrolwortmannin promotes the reaction [resveratrol results in decreased expression of BIRC5 protein]22137261
C059514resveratrolresveratrol results in decreased expression of BIRC5 mRNA24092990
C059514resveratrolresveratrol results in increased expression of BIRC5 mRNA23419489
D015474IsotretinoinIsotretinoin results in decreased expression of BIRC5 protein16135400
D012176RetinoidsRetinoids results in decreased expression of BIRC5 protein19067706
D019438RitonavirRitonavir results in decreased expression of BIRC5 mRNA16174765|2127066
D019438RitonavirRitonavir results in decreased expression of BIRC5 protein21270666
C087123romidepsin[romidepsin co-treated with Bortezomib] results in increased cleavage of BIRC5 protein18223231
C104586roscovitineroscovitine results in decreased expression of BIRC5 protein16230394
C089730rosiglitazonerosiglitazone results in decreased expression of BIRC5 mRNA19467017|1973182
C089730rosiglitazoneTretinoin promotes the reaction [rosiglitazone results in decreased expression of BIRC5 mRNA]19467017|1973182
C064116S-(1,1,2,2-tetrafluoroethyl)cysteine"S-(1,1,2,2-tetrafluoroethyl)cysteine results in decreased expression of BIRC5 mRNA"16678137
C093642SB 203580SB 203580 affects the reaction [[gambogic acid co-treated with Doxorubicin] affects the expression of BIRC5 protein]25824409
C093642SB 203580SB 203580 inhibits the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]16328441|2159458
C093642SB 203580SB 203580 inhibits the reaction [baicalein results in decreased expression of BIRC5 protein]18025287
C093642SB 203580SB 203580 inhibits the reaction [tanshinone results in decreased expression of BIRC5 mRNA]21165580
C093642SB 203580SB 203580 results in increased expression of BIRC5 mRNA21165580
C417521SB 216763SB 216763 results in increased expression of BIRC5 mRNA16288908
C115461SC 560SC 560 results in decreased expression of BIRC5 mRNA17270149
C115461SC 560SC 560 results in decreased expression of BIRC5 protein16391822|1727014
D012643SeleniumBIRC5 protein affects the susceptibility to Selenium17876054
D012643Selenium[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]27920530
D012643SeleniumSelenium analog inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]27920530
C078903seocalcitolseocalcitol results in decreased expression of BIRC5 protein18567002
D012822Silicon DioxideSilicon Dioxide results in increased expression of BIRC5 mRNA26345256
D012834SilverSilver results in decreased expression of BIRC5 mRNA27131904
C440975silybin[silybin co-treated with arsenic trioxide] results in decreased expression of BIRC5 mRNA21969006
C440975silybinsilybin results in decreased expression of BIRC524440808
C440975silybin[silybin results in decreased expression of BIRC5] which results in increased susceptibility to TNFSF10 protein24440808
D019821Simvastatin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Simvastatin results in decreased expression of BIRC5 protein]20464445
D019821SimvastatinSimvastatin inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]17277159
D019821SimvastatinSimvastatin promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of BIRC5 protein]20464445
D019821SimvastatinSimvastatin results in decreased expression of BIRC5 mRNA20464445
D019821SimvastatinSimvastatin results in decreased expression of BIRC5 protein20464445
D020123Sirolimus[fulvestrant co-treated with Sirolimus] results in decreased expression of BIRC5 mRNA19016759
D020123Sirolimus"Sirolimus inhibits the reaction [N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide results in increased expression of and affects the localization of BIRC5 protein]"24444656
D020123SirolimusSirolimus promotes the reaction [Tamoxifen results in decreased expression of BIRC5 protein]19931998
D020123SirolimusSirolimus results in decreased expression of BIRC5 protein19931998|2160156
C000619853SM-1 compound[SM-1 compound co-treated with Fluorouracil] results in decreased expression of BIRC5 mRNA28599477
C000619853SM-1 compoundSM-1 compound inhibits the reaction [Fluorouracil results in increased expression of BIRC5 mRNA]28599477
C000619853SM-1 compoundSM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BIRC5 protein]28599477
C000619853SM-1 compoundSM-1 compound results in decreased expression of BIRC5 mRNA28599477
C110881S-nitro-N-acetylpenicillamine4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [S-nitro-N-acetylpenicillamine results in decreased expression of BIRC5 protein]14988404
C110881S-nitro-N-acetylpenicillamineS-nitro-N-acetylpenicillamine results in decreased expression of BIRC5 mRNA14988404
C110881S-nitro-N-acetylpenicillamineS-nitro-N-acetylpenicillamine results in decreased expression of BIRC5 protein14988404
C017947sodium arsenitepyrazolanthrone inhibits the reaction [sodium arsenite results in decreased expression of BIRC5 mRNA]22706169
C017947sodium arsenitepyrazolanthrone inhibits the reaction [sodium arsenite results in decreased expression of BIRC5 protein]22706169
C017947sodium arseniteRELA mutant form inhibits the reaction [sodium arsenite results in increased expression of BIRC5 mRNA]22706169
C017947sodium arseniteRELA mutant form inhibits the reaction [sodium arsenite results in increased expression of BIRC5 protein]22706169
C017947sodium arsenitesodium arsenite results in decreased expression of BIRC5 mRNA16497974|2270616
C017947sodium arsenitesodium arsenite results in decreased expression of BIRC5 protein16497974|2270616
C017947sodium arsenite[sodium arsenite results in decreased expression of BIRC5] which results in increased activity of CASP3 protein16497974
C017947sodium arsenitesodium arsenite results in increased expression of BIRC5 mRNA22706169|2859598
C017947sodium arsenitesodium arsenite results in increased expression of BIRC5 protein14988404|2270616
C017947sodium arseniteTP53 mutant form inhibits the reaction [sodium arsenite results in decreased expression of BIRC5 protein]22706169
C017947sodium arseniteU 0126 inhibits the reaction [sodium arsenite results in increased expression of BIRC5 mRNA]22706169
C017947sodium arseniteU 0126 inhibits the reaction [sodium arsenite results in increased expression of BIRC5 protein]22706169
C017947sodium arsenitesodium arsenite results in decreased expression of BIRC5 mRNA17998272
C017947sodium arsenitesodium arsenite results in decreased expression of BIRC5 protein20336670
D012969Sodium FluorideSodium Fluoride results in increased expression of BIRC5 mRNA27862939
D053260SootSoot results in increased expression of BIRC5 mRNA22461453|2655175
C471405sorafenib[resveratrol co-treated with sorafenib] results in decreased expression of BIRC5 protein26911335
C471405sorafenibsorafenib analog results in decreased expression of BIRC5 protein21531053
C471405sorafenibsorafenib inhibits the reaction [IGF1 protein results in increased expression of BIRC5 protein]21601561
C471405sorafenibsorafenib results in decreased expression of BIRC5 mRNA26409325
C471405sorafenibsorafenib results in decreased expression of BIRC5 protein18200035|2047332
C471405sorafenib[[[sorafenib results in increased expression of ATF4 protein] which results in increased expression of DDIT4 protein] which results in decreased activity of MTOR protein] which results in decreased expression of BIRC5 protein21601561
C471405sorafenib[[sorafenib results in increased expression of DDIT4 protein] which results in decreased activity of MTOR protein] which results in decreased expression of BIRC5 protein21601561
C471405sorafenibsorafenib results in decreased expression of BIRC5 protein21750559
D013141Spiro CompoundsSpiro Compounds analog results in decreased expression of BIRC5 protein25320076
C517409statticstattic inhibits the reaction [glycine-extended gastrin 17 results in increased expression of BIRC5 mRNA]19153190
D019311StaurosporineStaurosporine results in decreased expression of BIRC5 protein16225760
D013467SulindacBIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein]17401459
D013467SulindacBIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein modified form]17401459
D013467Sulindac[Sulindac co-treated with arsenic trioxide] results in decreased expression of BIRC5 protein18281123
D013467Sulindac[Sulindac co-treated with vorinostat] results in decreased expression of BIRC5 mRNA18156316
D013467Sulindac[Sulindac co-treated with vorinostat] results in decreased expression of BIRC5 protein18156316
D013467SulindacSulindac results in decreased expression of BIRC5 mRNA11906190|1461021
D013467SulindacSulindac results in decreased expression of BIRC5 protein14610217|1740145
D013467Sulindac[Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of BIRC5 protein17136320
C473478sunitinibChloroquine promotes the reaction [sunitinib results in decreased expression of BIRC5 protein]24751611
C473478sunitinibsunitinib results in decreased expression of BIRC5 protein24751611
D016559TacrolimusTacrolimus results in decreased expression of BIRC5 mRNA16574167
D013629Tamoxifen[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Tamoxifen] results in decreased expression of BIRC5 mRNA22046442
D013629Tamoxifen[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Tamoxifen] results in decreased expression of BIRC5 protein22046442
D013629TamoxifenBIRC5 protein results in decreased susceptibility to Tamoxifen18815881
D013629TamoxifenBIRC5 results in decreased susceptibility to Tamoxifen18815881
D013629TamoxifenSirolimus promotes the reaction [Tamoxifen results in decreased expression of BIRC5 protein]19931998
D013629TamoxifenTamoxifen results in decreased expression of BIRC5 mRNA19931998
D013629TamoxifenTamoxifen results in decreased expression of BIRC5 protein19931998
D013629TamoxifenTamoxifen affects the expression of BIRC5 mRNA17555576
C021751tanshinoneSB 203580 inhibits the reaction [tanshinone results in decreased expression of BIRC5 mRNA]21165580
C021751tanshinonetanshinone inhibits the reaction [Cisplatin results in increased expression of BIRC5 mRNA]21165580
C021751tanshinonetanshinone results in decreased expression of BIRC5 mRNA21165580
C047246temozolomidetemozolomide results in decreased expression of BIRC5 protein28122345
C047246temozolomideXAF1 protein promotes the reaction [temozolomide results in decreased expression of BIRC5 protein]28122345
C076852terameprocolterameprocol results in decreased expression of BIRC5 mRNA15958646
C076852terameprocolterameprocol results in decreased expression of BIRC5 protein15958646
D013739TestosteroneCalcitriol promotes the reaction [Testosterone results in increased expression of BIRC5 mRNA]21592394
D013739Testosteronegingerol inhibits the reaction [Testosterone results in increased expression of BIRC5 protein]18030663
D013739Testosteronepyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 mRNA]16139439
D013739Testosteronepyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 protein]16139439
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of BIRC5 mRNA21592394
D013739TestosteroneTestosterone promotes the reaction [Calcitriol results in increased expression of BIRC5 mRNA]21592394
D013739TestosteroneTestosterone results in decreased expression of BIRC5 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of BIRC5 protein18030663
D013739Testosteronegingerol inhibits the reaction [Testosterone results in increased expression of BIRC5 protein]18030663
D013739TestosteroneTestosterone results in increased expression of BIRC5 protein18030663
C020806tetrabromobisphenol Atetrabromobisphenol A affects the expression of BIRC5 mRNA26988606
D013749TetrachlorodibenzodioxinAHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BIRC5 mRNA]15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of BIRC5 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BIRC5 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of BIRC5 mRNA15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BIRC5 mRNA19520675|2584352
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BIRC5 protein25843524
D013750TetrachloroethyleneTetrachloroethylene results in increased expression of BIRC5 mRNA19031421
C117155tetracycline CMT-3tetracycline CMT-3 results in decreased expression of BIRC5 protein15688368
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of BIRC5 mRNA19031421
C009438tetrandrinetetrandrine binds to BIRC5 promoter17968851
C009438tetrandrinetetrandrine results in decreased expression of BIRC5 mRNA18495333
D019284ThapsigarginThapsigargin results in increased expression of BIRC5 protein12609713
D019284ThapsigarginUrsodeoxycholic Acid inhibits the reaction [Thapsigargin results in increased expression of BIRC5 protein]12609713
D013849ThimerosalBIRC5 mutant form promotes the reaction [Thimerosal results in increased cleavage of CASP3 protein]23145070
D013849ThimerosalBIRC5 mutant form promotes the reaction [Thimerosal results in increased cleavage of CASP9 protein]23145070
D013849ThimerosalBIRC5 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP3 protein]23145070
D013849ThimerosalBIRC5 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP9 protein]23145070
D013849ThimerosalIGF1 protein inhibits the reaction [Thimerosal results in decreased expression of BIRC5 protein]23145070
D013849ThimerosalThimerosal promotes the reaction [BIRC5 mutant form results in increased cleavage of CASP3 protein]23145070
D013849ThimerosalThimerosal promotes the reaction [BIRC5 mutant form results in increased cleavage of CASP9 protein]23145070
D013849ThimerosalThimerosal results in decreased expression of BIRC5 protein23145070
D013853ThioacetamideThioacetamide results in increased expression of BIRC5 mRNA23411599
C009495titanium dioxide[Vitallium analog binds to titanium dioxide] which results in decreased expression of BIRC5 mRNA23825117
C009495titanium dioxidetitanium dioxide results in increased expression of BIRC5 mRNA23557971
D014028Tobacco Smoke PollutionNFE2L2 protein promotes the reaction [Tobacco Smoke Pollution affects the expression of BIRC5 mRNA]20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of BIRC5 mRNA20133372
D024505TocopherolsTocopherols results in increased expression of BIRC5 mRNA17056531
D019772Topotecanbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of BIRC5 protein]19812371
D019772Topotecan[Topotecan co-treated with pifithrin] results in increased degradation of BIRC5 protein19812371
D019772Topotecanbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of BIRC5 protein]19812371
D019772TopotecanTopotecan results in increased degradation of BIRC5 protein19812371
D019772TopotecanTRP53 inhibits the reaction [Topotecan results in increased degradation of BIRC5 protein]19812371
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of BIRC5 mRNA25729387
D019772TopotecanTopotecan results in decreased expression of BIRC5 mRNA25729387
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in decreased expression of BIRC5 mRNA"17951470
D014212TretinoinFLT3 gene mutant form promotes the reaction [[D-65476 co-treated with Tretinoin] results in decreased expression of BIRC5 mRNA]16473406
D014212TretinoinFLT3 gene mutant form promotes the reaction [[D-65476 co-treated with Tretinoin] results in decreased expression of BIRC5 protein]16473406
D014212Tretinoin[Tretinoin co-treated with Paclitaxel] results in decreased expression of BIRC5 protein17701358|1809827
D014212Tretinoin[Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 mRNA20349282
D014212Tretinoin[Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 protein20349282
D014212TretinoinTretinoin promotes the reaction [rosiglitazone results in decreased expression of BIRC5 mRNA]19467017|1973182
D014212TretinoinTretinoin results in decreased expression of BIRC5 mRNA16574167|2193413
D014212TretinoinTretinoin results in decreased expression of BIRC5 protein16135400|1770135
D014212TretinoinTretinoin results in increased expression of BIRC5 mRNA17198874
C032910triadimefonNR1H3 gene mutant form inhibits the reaction [triadimefon results in increased expression of BIRC5 mRNA]25949234
C032910triadimefontriadimefon results in increased expression of BIRC5 mRNA25949234
D014241TrichloroethyleneTrichloroethylene results in increased expression of BIRC5 mRNA25549359
C012589trichostatin Adecitabine inhibits the reaction [trichostatin A results in decreased expression of BIRC5 mRNA]18718068
C012589trichostatin Atrichostatin A results in decreased expression of BIRC5 mRNA18718068|1960601
C012589trichostatin Atrichostatin A results in decreased expression of BIRC5 protein23770000
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of BIRC5 mRNA19042947
C068051tripchlorolidetripchlorolide affects the reaction [TP53 protein affects the expression of BIRC5 mRNA]15916722
C050414tripterinetripterine results in decreased expression of BIRC5 mRNA17010675
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BIRC5 mRNA"26179874
C057693troglitazonetroglitazone affects the localization of BIRC5 protein18407589
C057693troglitazonetroglitazone results in decreased expression of BIRC5 mRNA16820965|1714393
C057693troglitazonetroglitazone results in decreased expression of BIRC5 protein16820965|1714393
C447031tyrphostin AG 1024tyrphostin AG 1024 inhibits the reaction [gefitinib results in increased expression of BIRC5 protein]17473213
C101044tyrphostin AG 1478[tyrphostin AG 1478 results in decreased activity of EGFR protein] which results in decreased expression of BIRC5 protein21268125
C113580U 0126U 0126 inhibits the reaction [arsenic trioxide results in decreased expression of BIRC5 protein]21594580
C113580U 0126U 0126 inhibits the reaction [sodium arsenite results in increased expression of BIRC5 mRNA]22706169
C113580U 0126U 0126 inhibits the reaction [sodium arsenite results in increased expression of BIRC5 protein]22706169
C000592878UMI-77UMI-77 results in decreased expression of BIRC5 protein24019208
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [Thapsigargin results in increased expression of BIRC5 protein]12609713
D014635Valproic AcidValproic Acid inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 mRNA]22711276
D014635Valproic AcidValproic Acid affects the expression of BIRC5 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of BIRC5 protein21771726
D014635Valproic AcidValproic Acid results in increased methylation of BIRC5 gene29154799
D001335Vehicle Emissions2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in decreased expression of BIRC5 mRNA]28655636
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of BIRC5 mRNA28655636
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of BIRC5 gene25560391
C551177vemurafenib[(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of BIRC5 mRNA27169980
C017963vinyl carbamatevinyl carbamate results in increased expression of BIRC5 mRNA17163412|1784945
C029297vinylidene chloridevinylidene chloride results in increased expression of BIRC5 mRNA26682919
D014800Vitallium[Vitallium analog binds to titanium dioxide] which results in decreased expression of BIRC5 mRNA23825117
D014800VitalliumVitallium analog results in decreased expression of BIRC5 mRNA23825117
D012256RiboflavinRiboflavin affects the expression of BIRC520848206
D014810Vitamin EVitamin E inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein]24664296
D024483Vitamin K 3Vitamin K 3 affects the expression of BIRC5 mRNA20044591
C111237vorinostatvorinostat inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 mRNA]22711276
C111237vorinostat[Sulindac co-treated with vorinostat] results in decreased expression of BIRC5 mRNA18156316
C111237vorinostat[Sulindac co-treated with vorinostat] results in decreased expression of BIRC5 protein18156316
C111237vorinostatTNFSF10 protein promotes the reaction [vorinostat results in decreased expression of BIRC5 protein]17410615
C111237vorinostatvorinostat affects the expression of BIRC5 protein20846458
C111237vorinostat[vorinostat co-treated with TNFSF10 protein] results in decreased expression of BIRC5 protein19643600
C111237vorinostatvorinostat inhibits the reaction [Paclitaxel results in increased expression of BIRC5 protein]19875160
C111237vorinostatvorinostat results in decreased expression of BIRC5 protein16144943|1741061
C111237vorinostat[VX680 co-treated with vorinostat] results in decreased phosphorylation of BIRC5 protein18829489
C484810VX680[VX680 co-treated with vorinostat] results in decreased phosphorylation of BIRC5 protein18829489
C484810VX680VX680 results in decreased phosphorylation of BIRC5 protein18829489
C009687wortmanninwortmannin promotes the reaction [baicalein results in decreased expression of BIRC5 protein]18025287
C009687wortmanninwortmannin results in decreased expression of BIRC5 mRNA15065019
C009687wortmanninwortmannin results in decreased expression of BIRC5 protein15065019
C009687wortmanninwortmannin promotes the reaction [resveratrol results in decreased expression of BIRC5 protein]22137261
C009687wortmanninwortmannin results in decreased expression of BIRC5 protein23145070
C523798YM 155"[N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide results in increased expression of BIRC5 protein] which affects the susceptibility to YM 155"24444656
C523798YM 155YM 155 results in decreased expression of BIRC5 mRNA23918355
C403304zerumbonezerumbone results in decreased expression of BIRC5 mRNA16007145
D015032ZincZinc deficiency results in increased expression of BIRC5 mRNA22171008
D019345Zinc Acetatemotexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of BIRC5 mRNA]16357179
D019345Zinc AcetateZinc Acetate results in increased expression of BIRC5 mRNA16357179
C088658zoledronic acid[Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 mRNA20349282
C088658zoledronic acid[Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 protein20349282
C088658zoledronic acidzoledronic acid results in decreased expression of BIRC5 mRNA24714768
C088658zoledronic acidzoledronic acid results in decreased expression of BIRC5 protein19036117

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI11024045  14610074  15665297  16239925  16291752  17099693  
17681274  17956729  18243099  19357306  20638385  20739936  
20826784  21051298  21225229  21536684  21988832  23251006  
23825075  24571573  25241761  27332895  29568061  
GO:0008017microtubule binding-TAS21536684  
GO:0008536Ran GTPase binding-IPI18591255  
GO:0019899enzyme binding-IPI16322459  
GO:0042802identical protein binding-IPI17099693  23251006  
GO:0046872metal ion binding-IEA-  
GO:0051087chaperone binding-IPI18086682  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006468protein phosphorylation-IDA21252625  
GO:0006915apoptotic process-IEA-  
GO:0007059chromosome segregation-IEA-  
GO:0007605sensory perception of sound-IEP20627126  
GO:0008284positive regulation of cell proliferation-TAS16344111  
GO:0016567protein ubiquitination-IEA-  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0031503protein-containing complex localization-IMP16239925  
GO:0042981regulation of apoptotic process-TAS-  
GO:0043066negative regulation of apoptotic process-IDA20627126  21364656  
GO:0043066negative regulation of apoptotic process-IMP21536684  
GO:0045892negative regulation of transcription, DNA-templated-IMP20826784  
GO:0051301cell division-IEA-  
GO:0090307mitotic spindle assembly-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0000228nuclear chromosome-IDA16322459  
GO:0000775chromosome, centromeric region-IDA11084331  16322459  
GO:0000777condensed chromosome kinetochore-IDA15665297  
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA15665297  20627126  20826784  21364656  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-IDA20627126  21364656  
GO:0005819spindle-IEA-  
GO:0005829cytosol-IDA18591255  
GO:0005829cytosol-TAS-  
GO:0005874microtubule-IEA-  
GO:0030496midbody-IDA11084331  15665297  
GO:0032133chromosome passenger complex-IPI15260989  18591255  
KEGG ID KEGG Term
hsa05200Pathways in cancer
hsa05210Colorectal cancer
Reactome ID Reactome Term Evidence
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-141424Amplification of signal from the kinetochoresTAS
R-HSA-141444Amplification of signal from unattached kinetochores via a MAD2 inhibitory signalTAS
R-HSA-162582Signal TransductionTAS
R-HSA-1640170Cell CycleTAS
R-HSA-168256Immune SystemTAS
R-HSA-194315Signaling by Rho GTPasesTAS
R-HSA-195258RHO GTPase EffectorsTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2467813Separation of Sister ChromatidsTAS
R-HSA-2500257Resolution of Sister Chromatid CohesionTAS
R-HSA-2555396Mitotic Metaphase and AnaphaseTAS
R-HSA-2990846SUMOylationTAS
R-HSA-3108232SUMO E3 ligases SUMOylate target proteinsTAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-4615885SUMOylation of DNA replication proteinsTAS
R-HSA-5633008TP53 Regulates Transcription of Cell Death GenesTAS
R-HSA-5663220RHO GTPases Activate ForminsTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-6803205TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertainTAS
R-HSA-68877Mitotic PrometaphaseTAS
R-HSA-68882Mitotic AnaphaseTAS
R-HSA-68886M PhaseTAS
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-69618Mitotic Spindle CheckpointTAS
R-HSA-69620Cell Cycle CheckpointsTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8951664NeddylationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28949095Differential protein-coding gene and long noncoding RNA expression in smoking-related lung squamous cell carcinoma. (2017 Nov)Li SThorac Cancer
29029509Establishment of oral squamous cell carcinoma cell line and magnetic bead-based isolation and characterization of its CD90/CD44 subpopulations. (2017 Sep 12)Svobodova MOncotarget