Gene: HSP90AB1

3326
D6S182|HSP84|HSP90B|HSPC2|HSPCB
heat shock protein 90 alpha family class B member 1
protein-coding
6p21.1
Ensembl:ENSG00000096384 MIM:140572 Vega:OTTHUMG00000014761 UniprotKB:P08238
NC_000006.12
PubMed
0   ANCO-SNPs
CD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.742e-1 (AD)  7.885e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MTCH10.953
RNF100.951
CCT70.942
CCT6A0.941
CCT40.94
ALDOA0.939
CCT20.938
CACYBP0.937
SRP680.936
DNAJB60.936

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.789
OR4F29-0.771
KLRB1-0.289
IL18RAP-0.272
KLRF1-0.272
VNN3-0.262
CCR2-0.255
ASB4-0.253
CEACAM4-0.252
KLF17-0.246

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB02424GeldanamycinSmall Molecule30562-34-6Experimental|InvestigationalTarget
DB027549-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-AmineSmall MoleculeExperimentalTarget
DB03758RadicicolSmall MoleculeExperimentalTarget
DB05134TanespimycinSmall Molecule75747-14-7InvestigationalTarget
DB06070SNX-5422Small MoleculeInvestigationalTarget
DB075944-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOLSmall MoleculeExperimentalTarget
DB078778-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINESmall MoleculeExperimentalTarget
DB080454-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOLSmall MoleculeExperimentalTarget
DB08153(5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONESmall MoleculeExperimentalTarget
DB08292(5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONESmall MoleculeExperimentalTarget
DB08293(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONESmall MoleculeExperimentalTarget
DB08346(5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONESmall MoleculeExperimentalTarget
DB08464METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATESmall MoleculeExperimentalTarget
DB084652-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATESmall MoleculeExperimentalTarget
DB09221PolaprezincSmall Molecule107667-60-7Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0256031,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Humic Substances results in increased expression of HSP90AB1 protein]"23836447
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of HSP90AB1 mRNA"15375163
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of HSP90AB1 mRNA"19162173
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of HSP90AB1 mRNA"28903501
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl affects the expression of HSP90AB1 mRNA"21703328
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of HSP90AB1 protein"21673325
C0109142,4-diaminotoluene"2,4-diaminotoluene results in decreased expression of HSP90AB1 mRNA"22016648
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of HSP90AB1 mRNA"21346803
C0094072,5,2',5'-tetrachlorobiphenyl"2,5,2',5'-tetrachlorobiphenyl results in increased expression of HSP90AB1 mRNA"21703328
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in decreased expression of HSP90AB1 mRNA"20406850
C0247092,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone"2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone binds to HSP90AB1 protein"16533022
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSP90AB1 mRNA"15215175
C0352082-amino-4,6-dinitrotoluene"2-amino-4,6-dinitrotoluene affects the expression of HSP90AB1 mRNA"21346803
C0303702-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone"2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone results in decreased expression of HSP90AB1 mRNA"20206263
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl affects the expression of HSP90AB1 mRNA"21703328
C0263083,4-dihydrocoumarin"3,4-dihydrocoumarin results in decreased expression of HSP90AB1 mRNA"22016648
C4800304-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid promotes the reaction [CHUK protein binds to HSP90AB1 protein]15930313
C4800304-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid results in increased expression of HSP90AB1 protein15930313
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of HSP90AB1 mRNA"18648102
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of HSP90AB1 mRNA"21346803
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal binds to HSP90AB1 protein21749116
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide affects the expression of HSP90AB1 mRNA20829426
C0417156-anilino-5,8-quinolinedione"6-anilino-5,8-quinolinedione results in increased expression of HSP90AB1 protein"10617604
D000082AcetaminophenAcetaminophen results in increased expression of HSP90AB1 mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of HSP90AB1 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of HSP90AB1 mRNA11743745|1295819
D000082AcetaminophenPTGS2 protein affects the reaction [Acetaminophen results in increased expression of HSP90AB1 mRNA]11743745
D020106AcrylamideAcrylamide results in increased expression of HSP90AB1 mRNA28959563
C016601afimoxifeneafimoxifene results in decreased expression of HSP90AB1 mRNA16514628
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of HSP90AB1 mRNA27153756
D015766Albendazole[Ivermectin co-treated with Albendazole] results in increased expression of HSP90AB1 mRNA16861626
D000517alpha-Chlorohydrinalpha-Chlorohydrin analog results in increased expression of HSP90AB1 protein26072098
D013196DihydrotestosteroneDihydrotestosterone results in decreased expression of HSP90AB1 mRNA17023530
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of HSP90AB1 mRNA17023530
D000643Ammonium ChlorideAmmonium Chloride affects the expression of HSP90AB1 mRNA16483693
C023650anilineaniline results in increased expression of HSP90AB1 mRNA22016648
D016718Arachidonic AcidArachidonic Acid results in decreased expression of HSP90AB1 mRNA16623957
C006632arsenic trioxidearsenic trioxide results in decreased expression of HSP90AB1 protein25419056
C006632arsenic trioxidearsenic trioxide results in increased expression of HSP90AB1 mRNA20458559|2252195
C006632arsenic trioxidearsenic trioxide results in increased expression of HSP90AB1 protein19364129
C006632arsenic trioxideHSP90AB1 protein affects the susceptibility to arsenic trioxide19371599
D017636Asbestos, Amphibole"Asbestos, Amphibole results in decreased expression of HSP90AB1 protein"20855422
D001205Ascorbic AcidAscorbic Acid affects the expression of HSP90AB1 protein19224539
D016589AstemizoleAstemizole results in decreased expression of HSP90AB1 mRNA20221588
D001280AtrazineAtrazine results in increased expression of HSP90AB1 mRNA22378314
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of HSP90AB1 mRNA15240111
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased mutagenesis of HSP90AB1 gene25435355
D001564Benzo(a)pyreneAHR protein affects the reaction [Benzo(a)pyrene affects the expression of HSP90AB1 mRNA]22228805
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of HSP90AB1 mRNA22342234
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of HSP90AB1 mRNA21569818|2374795
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [sodium arsenite results in increased expression of HSP90AB1 protein]16456883
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of HSP90AB1 protein16456883
D001564Benzo(a)pyrenesodium arsenite promotes the reaction [Benzo(a)pyrene results in increased expression of HSP90AB1 protein]16456883
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of HSP90AB1 mRNA"20018196
C038328BEP protocolBEP protocol results in increased expression of HSP90AB1 mRNA18987330
D004958EstradiolESR1 protein affects the reaction [Estradiol results in increased expression of HSP90AB1 mRNA]15223131
D004958EstradiolEstradiol affects the expression of HSP90AB1 mRNA22574217
D004958EstradiolEstradiol results in increased expression of HSP90AB1 mRNA15223131|1651462
C110172BHTOH-QMBHTOH-QM binds to HSP90AB1 protein16533022
D001647Bile Acids and SaltsBile Acids and Salts results in increased expression of HSP90AB1 protein11835266
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in increased expression of HSP90AB1 mRNA26606162
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HSP90AB1 mRNA28628672
C006780bisphenol Abisphenol A affects the expression of HSP90AB1 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of HSP90AB1 mRNA15223131
C006780bisphenol AESR1 protein affects the reaction [bisphenol A results in increased expression of HSP90AB1 mRNA]15223131
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HSP90AB1 mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of HSP90AB1 mRNA26063408
C006780bisphenol A[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of HSP90AB1 promoter23359474
C006780bisphenol Abisphenol A results in increased expression of HSP90AB1 mRNA15229138|2518105
C006780bisphenol Abisphenol A results in increased expression of HSP90AB1 protein15229138
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of HSP90AB1 mRNA28628672
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased phosphorylation of HSP90AB1 protein22174045
D000069286BortezomibBortezomib results in increased expression of HSP90AB1 mRNA17895889
C515564bromovaninbromovanin results in increased expression of HSP90AB1 protein21419150
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased expression of HSP90AB1 mRNA15707499
C026105butylidenephthalidebutylidenephthalide results in decreased expression of HSP90AB1 protein23770345
C018475butyraldehydebutyraldehyde results in increased expression of HSP90AB1 mRNA26079696
D002087ButyratesButyrates results in increased expression of HSP90AB1 mRNA22009386
D002087ButyratesButyrates results in decreased expression of HSP90AB1 mRNA14674679
C584509C646 compoundC646 compound results in decreased expression of HSP90AB1 mRNA26191083
D002104CadmiumCadmium inhibits the reaction [HSF1 protein binds to HSP90AB1 protein]28115653
D002104CadmiumCadmium results in increased expression of HSP90AB1 mRNA28115653
D002104CadmiumCadmium results in increased expression of HSP90AB1 protein28115653
D002104CadmiumCadmium results in increased metabolism of HSP90AB1 protein28115653
D002104CadmiumCadmium results in increased expression of HSP90AB1 mRNA24284285
D019256Cadmium ChlorideCadmium Chloride results in increased expression of HSP90AB1 protein22941245
D019256Cadmium ChlorideCadmium Chloride affects the expression of HSP90AB1 mRNA23828170
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of HSP90AB1 mRNA18560533
D019256Cadmium Chloride[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AB1 mRNA19840844
C037123cadmium sulfatecadmium sulfate results in increased expression of HSP90AB1 mRNA12064557|2178398
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of HSP90AB1 mRNA27339419
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of HSP90AB1 mRNA15963578
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of HSP90AB1 mRNA23650126
C100187chloropicrinchloropicrin affects the expression of HSP90AB1 mRNA26352163
D002737ChloropreneChloroprene results in increased expression of HSP90AB1 mRNA23125180
D002794CholineCholine affects the expression of HSP90AB1 mRNA17616785
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of HSP90AB1 mRNA28472532
D002994ClofibrateClofibrate results in decreased expression of HSP90AB1 mRNA17585979
D002994ClofibrateClofibrate results in increased expression of HSP90AB1 mRNA21318169
D002994ClofibrateClofibrate results in increased expression of HSP90AB1 protein16470657
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HSP90AB1 mRNA17602206
C018021cobaltous chloridecobaltous chloride results in increased expression of HSP90AB1 mRNA17553155
D003042CocaineCocaine results in decreased expression of HSP90AB1 mRNA17898221
D003300Copper[Disulfiram binds to Copper] which results in decreased expression of HSP90AB1 mRNA24690739
D019327Copper SulfateCopper Sulfate results in decreased expression of HSP90AB1 mRNA20599845
D019327Copper SulfateCopper Sulfate results in increased expression of HSP90AB1 mRNA19549813|2059984
D003375CoumestrolCoumestrol results in increased expression of HSP90AB1 mRNA15229138
D003375CoumestrolCoumestrol results in increased expression of HSP90AB1 protein15229138
D003471CuprizoneCuprizone results in decreased expression of HSP90AB1 mRNA26577399
D003471CuprizoneCuprizone results in increased expression of HSP90AB1 mRNA27523638
D003474CurcuminCurcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSP90AB1 mRNA]26361869
D003520CyclophosphamideCyclophosphamide results in decreased expression of HSP90AB1 mRNA11906922
D016572CyclosporineCyclosporine results in decreased methylation of HSP90AB1 promoter27989131
D016572CyclosporineCyclosporine results in increased expression of HSP90AB1 mRNA20106945
D003634DDTDDT results in decreased expression of HSP90AB1 mRNA19797855
C007262deoxynivalenoldeoxynivalenol affects the phosphorylation of HSP90AB1 protein23811945
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of HSP90AB1 mRNA]27941970
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HSP90AB1 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HSP90AB1 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of HSP90AB1 mRNA28628672
D003993Dibutyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of HSP90AB1 promoter23359474
D004051Diethylhexyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of HSP90AB1 promoter23359474
D004051Diethylhexyl PhthalateCurcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSP90AB1 mRNA]26361869
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of HSP90AB1 mRNA21318169|2636186
D004051Diethylhexyl Phthalateresveratrol promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSP90AB1 mRNA]26361869
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HSP90AB1 mRNA17602206
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSP90AB1 mRNA18544905
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid] results in increased expression of HSP90AB1 mRNA18544905
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of HSP90AB1 mRNA19638242|2036093
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of HSP90AB1 mRNA15229138
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of HSP90AB1 protein15229138
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of HSP90AB1 mRNA"22485181
D0151279,10-Dimethyl-1,2-benzanthracene"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of HSP90AB1 protein"22248470
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of HSP90AB1 protein"22248470
D004221Disulfiram[Disulfiram binds to Copper] which results in decreased expression of HSP90AB1 mRNA24690739
D004298DopamineDopamine results in increased expression of HSP90AB1 protein24675778
D004317DoxorubicinDoxorubicin affects the expression of HSP90AB1 protein29385562
D004317DoxorubicinDoxorubicin results in increased expression of HSP90AB1 mRNA22016648
D004391DustDust results in increased expression of HSP90AB1 mRNA17805423
C044101endotoxin, Escherichia coli"endotoxin, Escherichia coli results in increased expression of HSP90AB1 mRNA"15919760
C013525ENNG[ENNG co-treated with Isoflavones] results in increased expression of HSP90AB1 protein22248470
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of HSP90AB1 protein23301498
D004837Epinephrine[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HSP90AB1 protein19464573
D000431EthanolEthanol affects the expression of HSP90AB1 protein22960358
D000431EthanolEthanol results in increased expression of HSP90AB1 mRNA16784954
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of HSP90AB1 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of HSP90AB1 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSP90AB1 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of HSP90AB1 mRNA17108234
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of HSP90AB1 gene16495775
D011345FenofibrateFenofibrate results in increased expression of HSP90AB1 mRNA21318169
D011345FenofibratePPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA]21318169
D018120FinasterideFinasteride results in increased expression of HSP90AB1 mRNA24136188
D005485FlutamideFlutamide results in decreased expression of HSP90AB1 mRNA21126777
D005485FlutamideFlutamide results in increased expression of HSP90AB1 mRNA24136188
C070081fulvestrantfulvestrant results in decreased expression of HSP90AB1 mRNA16514628
C001277geldanamycingeldanamycin results in increased expression of HSP90AB1 mRNA26705709
C001277geldanamycingeldanamycin binds to HSP90AB1 protein21749116
D019833GenisteinGenistein results in increased expression of HSP90AB1 mRNA15229138
D019833GenisteinGenistein results in increased expression of HSP90AB1 protein15229138
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of HSP90AB1 mRNA22634610
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of HSP90AB1 mRNA22634610
D006046Gold[Gold co-treated with Polyethylene Glycols] results in decreased expression of HSP90AB1 mRNA19695318
D006581HexachlorobenzeneHexachlorobenzene results in decreased expression of HSP90AB1 mRNA15159207
D006812Humic Substances"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Humic Substances results in increased expression of HSP90AB1 protein]"23836447
D006812Humic SubstancesHumic Substances results in increased expression of HSP90AB1 protein23836447
D002112CalcifediolCalcifediol deficiency results in decreased expression of HSP90AB1 mRNA17293106
C001654hyperforinhyperforin affects the expression of HSP90AB1 protein15095150
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HSP90AB1 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HSP90AB1 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of HSP90AB1 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSP90AB1 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HSP90AB1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HSP90AB1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of HSP90AB1 mRNA28628672
D007529Isoflavones"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of HSP90AB1 protein"22248470
D007529Isoflavones[ENNG co-treated with Isoflavones] results in increased expression of HSP90AB1 protein22248470
D007559Ivermectin[Ivermectin co-treated with Albendazole] results in increased expression of HSP90AB1 mRNA16861626
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of HSP90AB1 mRNA12832151
C410337K 7174K 7174 results in decreased expression of HSP90AB1 mRNA24086573
D007657Ketone BodiesKetone Bodies results in decreased expression of HSP90AB1 mRNA15469884
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSP90AB1 mRNA18544905
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid] results in increased expression of HSP90AB1 mRNA18544905
C017461lead nitratelead nitrate affects the reaction [HSP90AB1 affects the expression of MT1 mRNA]11891201
C017461lead nitratelead nitrate affects the reaction [HSP90AB1 affects the expression of MT2 mRNA]11891201
C045463leflunomideleflunomide results in increased expression of HSP90AB1 mRNA24136188
C052901lemongrass oillemongrass oil affects the expression of HSP90AB1 mRNA25976427
C008281limonenelimonene results in increased expression of HSP90AB1 mRNA12815608
D008070Lipopolysaccharides[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of HSP90AB1 mRNA22777745
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of HSP90AB1 mRNA15919760
D008148LovastatinLovastatin results in decreased expression of HSP90AB1 mRNA20493250
C013099mancozebmancozeb results in increased expression of HSP90AB1 mRNA28330765
D008627Mercuric ChlorideMercuric Chloride affects the expression of HSP90AB1 mRNA20353558
D008746Methylazoxymethanol AcetateMethylazoxymethanol Acetate results in increased expression of HSP90AB1 mRNA28349193
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of HSP90AB1 protein22265609
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of HSP90AB1 mRNA16966085
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of HSP90AB1 mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of HSP90AB1 mRNA23649840
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AB1 mRNA19840844
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of HSP90AB1 protein24675778
C000873methylprednisolone acetatemethylprednisolone acetate results in increased expression of HSP90AB1 mRNA15693093
D009020MorphineMorphine results in increased expression of HSP90AB1 mRNA15497504
C437683motexafin gadoliniummotexafin gadolinium results in increased expression of HSP90AB1 mRNA16357179
C437683motexafin gadolinium[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSP90AB1 mRNA16357179
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of HSP90AB1 mRNA"29244179
C576667N-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamideN-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide analog inhibits the reaction [HSP90AB1 protein binds to PTGES3 protein]22895790
C576667N-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamideN-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide binds to and results in decreased activity of HSP90AB1 protein22895790
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of HSP90AB1 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of HSP90AB1 mRNA"25620056
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of HSP90AB1 mRNA20551477
C051752nefazodonenefazodone results in increased expression of HSP90AB1 mRNA24136188
C119536nickel acetateNFE2L2 protein inhibits the reaction [nickel acetate results in increased expression of HSP90AB1 mRNA]23023193
C119536nickel acetatenickel acetate affects the expression of HSP90AB1 mRNA23828170
C119536nickel acetatenickel acetate affects the expression of HSP90AB1 protein23828170
C119536nickel acetatenickel acetate results in decreased expression of HSP90AB1 mRNA23023193
C012655nimesulidenimesulide results in increased expression of HSP90AB1 mRNA24136188
C002741N-nitrosomorpholineN-nitrosomorpholine affects the expression of HSP90AB1 protein19716841
D016627OxidopamineOxidopamine results in increased expression of HSP90AB1 mRNA12486162
C016340o,p'-DDT"o,p'-DDT affects the expression of HSP90AB1 mRNA"17984292
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of HSP90AB1 mRNA17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of HSP90AB1 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of HSP90AB1 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of HSP90AB1 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of HSP90AB1 mRNA]17655762
D010126OzoneOzone results in increased expression of HSP90AB1 mRNA21543283
D010261ParaoxonParaoxon results in decreased expression of HSP90AB1 protein20931991
D052638Particulate Matteroxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of HSP90AB1 mRNA]17655762
D052638Particulate MatterParticulate Matter affects the expression of HSP90AB1 mRNA17655762
D052638Particulate MatterParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of HSP90AB1 mRNA]17655762
C410127PCB 180PCB 180 affects the expression of HSP90AB1 mRNA21703328
C008776pelargonic acidpelargonic acid results in increased expression of HSP90AB1 mRNA11379042
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of HSP90AB1 mRNA19162173|2131816
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of HSP90AB1 mRNA]19482888
D010634PhenobarbitalPhenobarbital results in increased expression of HSP90AB1 mRNA19482888
D010634PhenobarbitalPhenobarbital affects the expression of HSP90AB1 mRNA19162173
D010634PhenobarbitalPhenobarbital results in decreased expression of HSP90AB1 mRNA19162173
D010695PhlorhizinPhlorhizin results in decreased expression of HSP90AB1 mRNA22538082
C049032pinosylvinpinosylvin results in decreased expression of HSP90AB1 mRNA23333577
C006253pirinixic acidpirinixic acid results in increased expression of HSP90AB1 mRNA18301758|2381119
C006253pirinixic acidpirinixic acid results in increased expression of HSP90AB1 mRNA19162173|2131816
D010938Plant OilsPlant Oils results in increased expression of HSP90AB1 mRNA23370395
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls affects the expression of HSP90AB1 mRNA21334430
D011092Polyethylene Glycols[Gold co-treated with Polyethylene Glycols] results in decreased expression of HSP90AB1 mRNA19695318
D011192Potassium DichromatePotassium Dichromate results in decreased expression of HSP90AB1 protein23718831
C100573prostaglandin A1prostaglandin A1 analog results in increased metabolism of HSP90AB1 protein19800325
C031280pyrazolepyrazole results in increased expression of HSP90AB1 mRNA17945193
C030984pyrenepyrene results in increased expression of HSP90AB1 mRNA15963578
C010423pyrithione zincpyrithione zinc results in increased expression of HSP90AB1 mRNA21424779
D011794QuercetinQuercetin results in decreased expression of HSP90AB1 protein19207037
D011794QuercetinQuercetin results in decreased expression of HSP90AB1 mRNA17103110
D011794QuercetinQuercetin results in decreased expression of HSP90AB1 protein11318950|1809536
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in decreased expression of HSP90AB1 mRNA16514628
C059514resveratrolresveratrol promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSP90AB1 mRNA]26361869
D012176RetinoidsRetinoids results in decreased expression of HSP90AB1 protein28886987
D012402RotenoneRotenone results in decreased expression of HSP90AB1 mRNA23186747
D012402RotenoneRotenone results in increased expression of HSP90AB1 mRNA22016648
D012524SarinSarin results in decreased expression of HSP90AB1 protein25842371
D012643SeleniumSelenium results in increased expression of HSP90AB1 mRNA19244175
D012825Silicon[Silicon co-treated with Silicon Dioxide] results in increased expression of HSP90AB1 mRNA26079203
D012825Silicon[Silicon co-treated with Silicon Dioxide] results in increased expression of HSP90AB1 protein26079203
D012822Silicon Dioxide[Silicon co-treated with Silicon Dioxide] results in increased expression of HSP90AB1 mRNA26079203
D012822Silicon Dioxide[Silicon co-treated with Silicon Dioxide] results in increased expression of HSP90AB1 protein26079203
D012822Silicon DioxideSilicon Dioxide analog affects the secretion of HSP90AB1 protein25895662
C009277sodium arsenatesodium arsenate results in increased expression of HSP90AB1 mRNA16882884
C017947sodium arsenitesodium arsenite results in decreased expression of HSP90AB1 protein21925251
C017947sodium arsenitesodium arsenite results in increased expression of HSP90AB1 mRNA12119132
C017947sodium arseniteATM protein affects the reaction [sodium arsenite results in decreased expression of HSP90AB1 mRNA]18996350
C017947sodium arseniteCHEK2 protein affects the reaction [sodium arsenite results in decreased expression of HSP90AB1 mRNA]18996350
C017947sodium arsenitesodium arsenite promotes the reaction [TRP53 protein binds to HSP90AB1 promoter]18996350
C017947sodium arsenitesodium arsenite results in decreased expression of HSP90AB1 mRNA18996350
C017947sodium arsenitesodium arsenite results in increased expression of HSP90AB1 mRNA16014739|1632224
C017947sodium arseniteBenzo(a)pyrene promotes the reaction [sodium arsenite results in increased expression of HSP90AB1 protein]16456883
C017947sodium arsenitesodium arsenite promotes the reaction [Benzo(a)pyrene results in increased expression of HSP90AB1 protein]16456883
C017947sodium arsenitesodium arsenite results in increased expression of HSP90AB1 protein16456883
C016104sodium bichromatesodium bichromate results in decreased expression of HSP90AB1 mRNA22561333
C016104sodium bichromatesodium bichromate results in increased expression of HSP90AB1 mRNA25993096
D017673Sodium Chloride, Dietary"Sodium Chloride, Dietary deficiency results in increased expression of and affects the localization of HSP90AB1 protein"15497505
D017673Sodium Chloride, Dietary"Sodium Chloride, Dietary deficiency results in increased expression of HSP90AB1 mRNA"15497505
D012969Sodium FluorideSodium Fluoride results in increased expression of HSP90AB1 protein27548804
D018038Sodium SeleniteSodium Selenite results in increased expression of HSP90AB1 mRNA18175754
D012460SulfasalazineSulfasalazine results in increased expression of HSP90AB1 mRNA22016648
D013605T-2 ToxinT-2 Toxin affects the expression of HSP90AB1 protein26141394
D013605T-2 ToxinT-2 Toxin results in decreased expression of HSP90AB1 mRNA26141394
C061133tamibarotenetamibarotene affects the expression of HSP90AB1 mRNA15498508
D013629TamoxifenTamoxifen affects the expression of HSP90AB1 mRNA17555576
C112765tanespimycintanespimycin binds to HSP90AB1 protein22895790
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of HSP90AB1 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSP90AB1 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of HSP90AB1 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of HSP90AB1 mRNA21215274
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of HSP90AB1 protein16548065
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSP90AB1 mRNA25613284
D013849ThimerosalThimerosal results in decreased expression of HSP90AB1 mRNA27188386
D013883ThiostreptonThiostrepton results in increased expression of HSP90AB1 mRNA22321511
D013893ThiramThiram results in decreased expression of HSP90AB1 mRNA20530235
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of HSP90AB1 mRNA22363418|2806579
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of HSP90AB1 protein27319396
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in decreased expression of HSP90AB1 mRNA"11379042
D014118Toxins, Biological"Toxins, Biological affects the expression of HSP90AB1 mRNA"19682533
D014212TretinoinTretinoin results in decreased expression of HSP90AB1 mRNA20530235
D014212TretinoinTretinoin results in decreased expression of HSP90AB1 mRNA15498508|1721838
D014212TretinoinTretinoin results in increased acetylation of HSP90AB1 protein28053092
D014241TrichloroethyleneTrichloroethylene results in decreased expression of HSP90AB1 mRNA28973375
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of HSP90AB1 mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of HSP90AB1 mRNA"25242413
C031324tris(chloroethyl)phosphatetris(chloroethyl)phosphate results in decreased expression of HSP90AB1 mRNA27776230
C057693troglitazonetroglitazone results in increased expression of HSP90AB1 mRNA19631733
D014501UraniumUranium affects the expression of HSP90AB1 mRNA15672453
D014501UraniumUranium affects the expression of HSP90AB1 protein15672453
D017974Uranium CompoundsUranium Compounds results in decreased expression of HSP90AB1 mRNA19654044
C005460uranyl acetateuranyl acetate affects the expression of HSP90AB1 mRNA15672453
C005460uranyl acetateuranyl acetate affects the expression of HSP90AB1 protein15672453
C073339usnic acid[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of HSP90AB1 mRNA22777745
C406224valdecoxibvaldecoxib results in increased expression of HSP90AB1 mRNA24136188
D014635Valproic AcidValproic Acid results in increased expression of HSP90AB1 mRNA21318169
D001335Vehicle Emissionsoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of HSP90AB1 mRNA]17655762
D001335Vehicle EmissionsVehicle Emissions affects the expression of HSP90AB1 mRNA17655762
D001335Vehicle EmissionsVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of HSP90AB1 mRNA]17655762
C025643vinclozolinvinclozolin affects the expression of HSP90AB1 mRNA19015723
D014810Vitamin EVitamin E results in increased expression of HSP90AB1 mRNA19244175
C111237vorinostatvorinostat results in decreased expression of HSP90AB1 mRNA27188386
C111237vorinostatvorinostat results in decreased expression of HSP90AB1 protein20543569
D014859WarfarinWarfarin results in decreased expression of HSP90AB1 mRNA20493250
D019820Xanthine[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HSP90AB1 protein19464573
D019820Xanthine[Xanthine co-treated with XDH protein] results in decreased expression of HSP90AB1 protein19464573
D019345Zinc Acetate[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSP90AB1 mRNA16357179
D019345Zinc AcetateZinc Acetate results in increased expression of HSP90AB1 mRNA16357179
D015054ZymosanZymosan results in increased expression of HSP90AB1 mRNA19061961

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0002134UTP binding-IEA-  
GO:0002135CTP binding-IEA-  
GO:0003723RNA binding-HDA22658674  22681889  
GO:0003725double-stranded RNA binding-IDA21266579  
GO:0005515protein binding-IPI11036079  14743216  15358771  15581363  15657067  15870294  
16263121  16293251  16314389  16330544  16531226  16580629  
16698020  17932509  17979178  18239673  18320024  18818696  
19375531  20029029  20374249  20618441  21170051  21183720  
21360678  21730179  21988832  22022502  22843495  22939624  
23349634  23414517  23428871  23431407  23455922  23585225  
24189400  24581495  24613385  24618592  24658140  24880080  
25036637  25241761  25416956  25486457  25609649  25910212  
26496610  26517842  27339980  28330616  29127155  29568061  
GO:0005524ATP binding-IDA10811660  
GO:0005524ATP binding-IMP10543959  
GO:0005525GTP binding-IEA-  
GO:0017098sulfonylurea receptor binding-IEA-  
GO:0019887protein kinase regulator activity-IEA-  
GO:0019900kinase binding-IPI20353823  21855797  
GO:0019901protein kinase binding-IEA-  
GO:0023026MHC class II protein complex binding-HDA20458337  
GO:0030235nitric-oxide synthase regulator activity-ISS-  
GO:0030911TPR domain binding-ISS-  
GO:0031072heat shock protein binding-IPI20353823  
GO:0031625ubiquitin protein ligase binding-IPI16207813  
GO:0032564dATP binding-IEA-  
GO:0042277peptide binding-IPI20599762  
GO:0042623ATPase activity, coupled-TAS-  
GO:0042802identical protein binding-IPI21183720  22939624  
GO:0042803protein homodimerization activity-IDA10811660  
GO:0042826histone deacetylase binding-IPI16809764  
GO:0043008ATP-dependent protein binding-IPI10543959  10811660  
GO:0044325ion channel binding-IEA-  
GO:0045296cadherin binding-HDA25468996  
GO:0046983protein dimerization activity-IDA7588731  
GO:0048156tau protein binding-IEA-  
GO:0051082unfolded protein binding-IEA-  
GO:0070182DNA polymerase binding-IPI10197982  19751963  
GO:0097718disordered domain specific binding-IPI11785981  15713458  
GO:1990226histone methyltransferase binding-IPI24880080  
GO ID GO Term Qualifier Evidence PubMed
GO:0001890placenta development-IEA-  
GO:0006457protein folding-IEA-  
GO:0006805xenobiotic metabolic process-TAS-  
GO:0006986response to unfolded protein-NAS2768249  
GO:0007004telomere maintenance via telomerase-IDA10197982  
GO:0009651response to salt stress-IEA-  
GO:0019062virion attachment to host cell-IMP24098578  
GO:0021955central nervous system neuron axonogenesis-ISS-  
GO:0030010establishment of cell polarity-ISS-  
GO:0030511positive regulation of transforming growth factor beta receptor signaling pathway-IDA24613385  
GO:0031396regulation of protein ubiquitination-IDA16809764  
GO:0032092positive regulation of protein binding-IEA-  
GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process-IDA24613385  
GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process-IMP16280321  
GO:0032516positive regulation of phosphoprotein phosphatase activity-IDA26593036  
GO:0033138positive regulation of peptidyl-serine phosphorylation-ISS-  
GO:0033160positive regulation of protein import into nucleus, translocation-IEA-  
GO:0035690cellular response to drug-IEA-  
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis-TAS-  
GO:0042220response to cocaine-IEA-  
GO:0043312neutrophil degranulation-TAS-  
GO:0043524negative regulation of neuron apoptotic process-IEA-  
GO:0045429positive regulation of nitric oxide biosynthetic process-ISS-  
GO:0045597positive regulation of cell differentiation-IMP18239673  
GO:0045793positive regulation of cell size-IEA-  
GO:0048675axon extension-ISS-  
GO:0050821protein stabilization-TAS-  
GO:0051131chaperone-mediated protein complex assembly-IDA10811660  
GO:0051248negative regulation of protein metabolic process-ISS17517623  
GO:0051897positive regulation of protein kinase B signaling-ISS-  
GO:0051973positive regulation of telomerase activity-IDA10197982  
GO:0060334regulation of interferon-gamma-mediated signaling pathway-IMP16280321  
GO:0060338regulation of type I interferon-mediated signaling pathway-IMP16280321  
GO:0071157negative regulation of cell cycle arrest-IMP22843495  
GO:0071353cellular response to interleukin-4-IEA-  
GO:0071407cellular response to organic cyclic compound-IEA-  
GO:0071902positive regulation of protein serine/threonine kinase activity-IEA-  
GO:0097435supramolecular fiber organization-IMP24466266  
GO:1900034regulation of cellular response to heat-TAS-  
GO:1901389negative regulation of transforming growth factor beta activation-IDA20599762  
GO:1901799negative regulation of proteasomal protein catabolic process-ISS17517623  
GO:1902949positive regulation of tau-protein kinase activity-IC-  
GO:1903660negative regulation of complement-dependent cytotoxicity-IEA-  
GO:1903827regulation of cellular protein localization-ISS-  
GO:1904031positive regulation of cyclin-dependent protein kinase activity-ISS17517623  
GO:1905323telomerase holoenzyme complex assembly-IDA10197982  
GO:2000010positive regulation of protein localization to cell surface-IDA23431407  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IDA20599762  
GO:0005576extracellular region-TAS-  
GO:0005634nucleus-IDA18239673  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IDA10791971  11785981  16580629  18239673  24880080  
GO:0005739mitochondrion-HDA20833797  
GO:0005765lysosomal membrane-IEA-  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0008180COP9 signalosomecolocalizes_withIDA18850735  
GO:0009986cell surface-IEA-  
GO:0016020membrane-HDA19946888  
GO:0016234inclusion body-IEA-  
GO:0016323basolateral plasma membrane-IEA-  
GO:0016324apical plasma membrane-IEA-  
GO:0031526brush border membrane-IEA-  
GO:0032991protein-containing complex-IDA10811660  23349634  
GO:0032991protein-containing complex-IMP10543959  
GO:0034751aryl hydrocarbon receptor complex-IDA15581363  
GO:0034774secretory granule lumen-TAS-  
GO:0042470melanosome-IEA-  
GO:0043025neuronal cell body-ISS-  
GO:0044294dendritic growth cone-ISS-  
GO:0044295axonal growth cone-ISS-  
GO:0048471perinuclear region of cytoplasm-ISS-  
GO:0070062extracellular exosome-HDA20458337  23533145  
GO:1904813ficolin-1-rich granule lumen-TAS-  
GO:1990913sperm head plasma membrane-IEA-  
GO:1990917ooplasm-IEA-  
KEGG ID KEGG Term
hsa04141Protein processing in endoplasmic reticulum
hsa04612Antigen processing and presentation
hsa04621NOD-like receptor signaling pathway
hsa04914Progesterone-mediated oocyte maturation
hsa05200Pathways in cancer
hsa05215Prostate cancer
Reactome ID Reactome Term Evidence
R-HSA-1266738Developmental BiologyTAS
R-HSA-1430728MetabolismTAS
R-HSA-162582Signal TransductionTAS
R-HSA-1640170Cell CycleTAS
R-HSA-1643685DiseaseTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-168643Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathwaysTAS
R-HSA-2029480Fcgamma receptor (FCGR) dependent phagocytosisTAS
R-HSA-2029482Regulation of actin dynamics for phagocytic cup formationTAS
R-HSA-211859Biological oxidationsTAS
R-HSA-211945Phase I - Functionalization of compoundsTAS
R-HSA-2262752Cellular responses to stressTAS
R-HSA-3371497HSP90 chaperone cycle for steroid hormone receptors (SHR)TAS
R-HSA-3371511HSF1 activationTAS
R-HSA-3371556Cellular response to heat stressTAS
R-HSA-3371568Attenuation phaseTAS
R-HSA-3371571HSF1-dependent transactivationTAS
R-HSA-373755Semaphorin interactionsTAS
R-HSA-399954Sema3A PAK dependent Axon repulsionTAS
R-HSA-422475Axon guidanceTAS
R-HSA-453274Mitotic G2-G2/M phasesTAS
R-HSA-5336415Uptake and function of diphtheria toxinTAS
R-HSA-5339562Uptake and actions of bacterial toxinsTAS
R-HSA-5663205Infectious diseaseTAS
R-HSA-622312InflammasomesTAS
R-HSA-6798695Neutrophil degranulationTAS
R-HSA-69275G2/M TransitionTAS
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-844456The NLRP3 inflammasomeTAS
R-HSA-8852276The role of GTSE1 in G2/M progression after G2 checkpointTAS
R-HSA-8937144Aryl hydrocarbon receptor signallingTAS
R-HSA-8939211ESR-mediated signalingTAS
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-9006931Signaling by Nuclear ReceptorsTAS
R-HSA-9018519Estrogen-dependent gene expressionTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
22860061Cocaine withdrawal causes delayed dysregulation of stress genes in the hippocampus. (2012)Garcia-Fuster MJPLoS One