C504317 | 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-((5-(4-fluorophenyl)-3-pyridinyl)methyl)piperazine | "[N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-((5-(4-fluorophenyl)-3-pyridinyl)methyl)piperazine" | 15996562 |
C106973 | 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide | "1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide binds to and results in decreased activity of HTR1A protein" | 9163561 |
C106973 | 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide | "1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide binds to and results in decreased activity of HTR1A protein" | 22050051 |
C106973 | 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide | "1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide binds to HTR1A protein" | 12023549 |
C106973 | 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide | "1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide binds to and results in decreased activity of HTR1A protein" | 22050051 |
C106973 | 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide | "1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide binds to and affects the activity of HTR1A protein" | 9809859 |
C106973 | 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide | "1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide binds to and results in decreased activity of HTR1A protein" | 22050051|9548383 |
C058895 | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein | 9163561 |
C058895 | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein | 15482641 |
C058895 | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine | [1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine | 15213358 |
C058895 | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine | [1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Serotonin | 16528294 |
C058895 | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein | 10764922|1521335 |
C507420 | 1,3,4,14b-tetrahydro-2,10-dimethyl-2H,10H-pyrazino(2,1-d)pyrrolo(1,2-b) (1,2,5)benzotriazepine | "1,3,4,14b-tetrahydro-2,10-dimethyl-2H,10H-pyrazino(2,1-d)pyrrolo(1,2-b) (1,2,5)benzotriazepine analog binds to HTR1A protein" | 16223499 |
C404207 | 1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone | "1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone binds to and results in increased activity of HTR1A protein" | 11907181 |
C015068 | 1-(3-chlorophenyl)piperazine | [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine | 8539317 |
C015068 | 1-(3-chlorophenyl)piperazine | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine | 8539317 |
C092824 | 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride | [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine | 8539317 |
C092824 | 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride | [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine | 8539317 |
C092824 | 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride | [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine | 8539317 |
C092824 | 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride | tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] | 8539317 |
C092824 | 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride | tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] | 8539317 |
C092824 | 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride | 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein | 8539317 |
C118559 | 1-bromopropane | 1-bromopropane results in decreased expression of HTR1A mRNA | 19576243 |
C010654 | (2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane | "(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to and affects the activity of HTR1A protein" | 15482641 |
C010654 | (2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane | "(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein" | 2891550 |
C010654 | (2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane | "Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein]" | 2891550 |
C570401 | 2-(6-((3,4-dihydro-2H-chromen-2-ylmethyl)amino)hexyl)tetrahydro-1H-pyrrolo(1,2-c)imidazole-1,3(2H)-dione | "2-(6-((3,4-dihydro-2H-chromen-2-ylmethyl)amino)hexyl)tetrahydro-1H-pyrrolo(1,2-c)imidazole-1,3(2H)-dione binds to and results in increased activity of HTR1A protein" | 22029386 |
C045392 | 2-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine | "2-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine binds to HTR1A protein" | 9723970 |
C480819 | (3-exo)-8-benzoyl-N-(((2S)7-chloro-2,3-dihydro-1,4-benzodioxin-1-yl)methyl)-8-azabicyclo(3.2.1)octane-3-methanamine monohydrochloride | "(3-exo)-8-benzoyl-N-(((2S)7-chloro-2,3-dihydro-1,4-benzodioxin-1-yl)methyl)-8-azabicyclo(3.2.1)octane-3-methanamine monohydrochloride binds to and results in increased activity of HTR1A protein" | 12902993 |
C087205 | 4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine | 4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine] | 10640309 |
C087205 | 4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine | 4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine binds to and results in decreased activity of HTR1A protein | 10640309 |
C008745 | 4,4'-bisphenol F | "4,4'-bisphenol F results in decreased expression of HTR1A mRNA" | 26186136 |
C079549 | 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine | 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and affects the activity of HTR1A protein | 9163561 |
C079549 | 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine | [4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine Hydrobromide | 10578133 |
C079549 | 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [[4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine Hydrobromide] | 10578133 |
C079549 | 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine | 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A protein | 18581099 |
C047087 | 5-carboxamidotryptamine | 5-carboxamidotryptamine binds to and results in increased activity of HTR1A protein | 15482641 |
C025145 | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole | "5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole binds to and affects the activity of HTR1A protein" | 9163561 |
C057446 | 5-methylurapidil | 5-methylurapidil binds to and results in increased activity of HTR1A protein | 15482641 |
C057446 | 5-methylurapidil | 5-methylurapidil binds to and results in increased activity of HTR1A protein | 7906241 |
C434584 | 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine | "8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]" | 11927170 |
C083828 | 8-hydroxy-2-(N-n-propyl-N-(3'-iodo-2'-propenyl)amino)tetralin | 8-hydroxy-2-(N-n-propyl-N-(3'-iodo-2'-propenyl)amino)tetralin binds to and results in increased activity of HTR1A protein | 18573488 |
C083828 | 8-hydroxy-2-(N-n-propyl-N-(3'-iodo-2'-propenyl)amino)tetralin | HTR1A protein results in increased susceptibility to 8-hydroxy-2-(N-n-propyl-N-(3'-iodo-2'-propenyl)amino)tetralin | 18573488 |
C083828 | 8-hydroxy-2-(N-n-propyl-N-(3'-iodo-2'-propenyl)amino)tetralin | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [HTR1A protein results in increased susceptibility to 8-hydroxy-2-(N-n-propyl-N-(3'-iodo-2'-propenyl)amino)tetralin] | 18573488 |
C095427 | A 86929 | A 86929 binds to HTR1A protein | 8558425 |
D000242 | Cyclic AMP | Arachidonic Acid metabolite inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] | 11356925 |
D000242 | Cyclic AMP | HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP] | 11356925 |
D000242 | Cyclic AMP | [JB-788 binds to and results in increased activity of HTR1A protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP] | 20580787 |
D000242 | Cyclic AMP | Melitten inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] | 11356925 |
D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased methylation of HTR1A gene | 27153756 |
D000393 | Air Pollutants | Air Pollutants analog results in increased expression of HTR1A mRNA | 21757418 |
C014959 | albiflorin | albiflorin affects the expression of HTR1A | 26475043 |
C050408 | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol binds to and results in increased activity of HTR1A protein | 19283364 |
C010846 | alverine | alverine binds to HTR1A protein | 11697552 |
C439263 | AM 1241 | AM 1241 binds to HTR1A protein | 18931146 |
D000639 | Amitriptyline | Amitriptyline results in increased expression of HTR1A protein | 1589591 |
D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of HTR1A mRNA | 16483693 |
D045930 | Anabolic Agents | Anabolic Agents results in decreased expression of HTR1A protein | 16914188 |
D001058 | Apomorphine | [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine | 8539317 |
D001058 | Apomorphine | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine | 8539317 |
D001058 | Apomorphine | tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] | 8539317 |
D001058 | Apomorphine | tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] | 8539317 |
D016718 | Arachidonic Acid | Arachidonic Acid metabolite inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] | 11356925 |
D000068180 | Aripiprazole | Aripiprazole binds to and affects the activity of HTR1A protein | 21823597 |
D000068180 | Aripiprazole | Aripiprazole binds to and results in increased activity of HTR1A protein | 17069544 |
D000068180 | Aripiprazole | Aripiprazole binds to and results in increased activity of HTR1A protein | 15830832|1741423 |
D000068180 | Aripiprazole | Aripiprazole binds to HTR1A protein | 18363460 |
D001151 | Arsenic | Arsenic results in increased activity of HTR1A protein | 18573533 |
C015001 | arsenite | arsenite results in increased methylation of HTR1A promoter | 23974009 |
D001280 | Atrazine | Atrazine results in decreased expression of HTR1A mRNA | 25929836 |
C473959 | befiradol | befiradol binds to and results in increased activity of HTR1A protein | 12595749 |
D001549 | Benzamides | Benzamides analog binds to and results in increased activity of HTR1A protein | 8676355 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of HTR1A mRNA | 19428949 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of HTR1A mRNA | 22212102 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of HTR1A mRNA | 21839799 |
D004958 | Estradiol | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of HTR1A mRNA | 20823114 |
D004958 | Estradiol | Estradiol promotes the reaction [PARP1 protein binds to HTR1A promoter mutant form] | 21990073 |
D004958 | Estradiol | [Estradiol promotes the reaction [PARP1 protein binds to HTR1A promoter mutant form]] which results in decreased expression of HTR1A mRNA | 21990073|2199007 |
D004958 | Estradiol | [Estradiol co-treated with Sertraline] affects the expression of HTR1A mRNA | 18650020 |
D004958 | Estradiol | Estradiol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of OXT protein modified form] | 22265196 |
D004958 | Estradiol | Estradiol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of POMC protein modified form] | 22265196 |
D004958 | Estradiol | Estradiol results in decreased expression of HTR1A protein | 22265196 |
D004958 | Estradiol | Estradiol results in increased expression of HTR1A mRNA | 22265196 |
D004958 | Estradiol | GPER1 protein affects the reaction [Estradiol results in decreased expression of HTR1A protein] | 22265196 |
C509981 | bifeprunox | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to bifeprunox | 15996562 |
C063249 | binospirone mesylate | binospirone mesylate binds to and results in increased activity of HTR1A protein | 15482641 |
C063249 | binospirone mesylate | binospirone mesylate binds to and affects the activity of HTR1A protein | 11526961 |
C543008 | bis(4-hydroxyphenyl)sulfone | bis(4-hydroxyphenyl)sulfone results in decreased expression of HTR1A mRNA | 26186136 |
C006780 | bisphenol A | bisphenol A results in decreased methylation of HTR1A promoter | 27271280 |
C006780 | bisphenol A | bisphenol A results in decreased methylation of HTR1A promoter | 27312807 |
C006780 | bisphenol A | bisphenol A results in increased methylation of HTR1A promoter | 27312807 |
C006780 | bisphenol A | bisphenol A results in decreased expression of HTR1A mRNA | 25181051|2618613 |
C053428 | BMY 7378 | BMY 7378 binds to and results in increased activity of HTR1A protein | 15482641 |
D002065 | Buspirone | Buspirone binds to and results in increased activity of HTR1A protein | 9163561 |
D002065 | Buspirone | Buspirone binds to and affects the activity of HTR1A protein | 15482641 |
D002065 | Buspirone | Buspirone binds to and results in decreased activity of HTR1A protein | 2207497 |
D002065 | Buspirone | Buspirone binds to and results in decreased activity of HTR1A protein | 15899244 |
D002065 | Buspirone | Buspirone binds to and results in increased activity of HTR1A protein | 10640309|1092107 |
D002065 | Buspirone | Buspirone binds to HTR1A protein | 11494197 |
D002118 | Calcium | Calcium results in increased activity of HTR1A protein | 11356925 |
D002220 | Carbamazepine | [Fluoxetine co-treated with Venlafaxine Hydrochloride co-treated with Carbamazepine] results in decreased expression of HTR1A mRNA | 22701549 |
C043211 | carvedilol | carvedilol binds to HTR1A protein | 2462161 |
C043211 | carvedilol | carvedilol inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 2462161 |
D002749 | Chlorprothixene | "Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein]" | 2891550 |
D004390 | Chlorpyrifos | Chlorpyrifos affects the expression of HTR1A mRNA | 17452286|1883540 |
D004390 | Chlorpyrifos | Chlorpyrifos results in increased expression of HTR1A | 17035140 |
C017133 | chromous chloride | HTR1A protein results in increased susceptibility to chromous chloride | 19211994 |
D002994 | Clofibrate | Clofibrate results in decreased expression of HTR1A mRNA | 17585979 |
D003024 | Clozapine | Clozapine binds to and affects the activity of HTR1A protein | 15482641 |
D003024 | Clozapine | Clozapine binds to HTR1A protein | 9723970 |
D003042 | Cocaine | Cocaine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 9723786 |
D005576 | Colforsin | Arachidonic Acid metabolite inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] | 11356925 |
D005576 | Colforsin | HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP] | 11356925 |
D005576 | Colforsin | [JB-788 binds to and results in increased activity of HTR1A protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP] | 20580787 |
D005576 | Colforsin | Melitten inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] | 11356925 |
D003471 | Cuprizone | Cuprizone results in decreased expression of HTR1A mRNA | 26577399 |
D003474 | Curcumin | Curcumin affects the expression of HTR1A mRNA | 17617388 |
D003634 | DDT | DDT results in decreased expression of HTR1A mRNA | 28263910 |
D003891 | Desipramine | Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of HTR1A mRNA] | 15885359 |
D003891 | Desipramine | Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of HTR1A protein] | 15885359 |
D003891 | Desipramine | Desipramine results in increased expression of HTR1A protein | 1589591 |
D003907 | Dexamethasone | Dexamethasone results in increased expression of HTR1A protein | 16160705 |
D003976 | Diazinon | Diazinon promotes the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 17035140 |
D003976 | Diazinon | Diazinon results in increased expression of HTR1A protein | 17035140 |
D003994 | Bucladesine | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of HTR1A mRNA | 20823114 |
D004026 | Dieldrin | Dieldrin results in decreased expression of HTR1A mRNA | 18835401 |
D004316 | Doxepin | Doxepin results in increased expression of HTR1A protein | 1589591 |
C063828 | eltoprazine | eltoprazine binds to and affects the activity of HTR1A protein | 9163561 |
C115127 | eptapirone | eptapirone binds to and results in increased activity of HTR1A protein | 12398907 |
D000431 | Ethanol | Ethanol results in increased expression of HTR1A mRNA | 18672336 |
D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of HTR1A mRNA | 29097150 |
C013528 | etoperidone | etoperidone binds to HTR1A protein | 7855217 |
C056895 | flesinoxan | flesinoxan binds to and results in increased activity of HTR1A protein | 9163561 |
C056895 | flesinoxan | Pindolol inhibits the reaction [flesinoxan binds to and results in increased activity of HTR1A protein] | 9163561 |
C056895 | flesinoxan | UH 301 inhibits the reaction [flesinoxan binds to and results in increased activity of HTR1A protein] | 9163561 |
C056895 | flesinoxan | WAY 100135 inhibits the reaction [flesinoxan binds to and results in increased activity of HTR1A protein] | 9163561 |
C056895 | flesinoxan | flesinoxan binds to and affects the activity of HTR1A protein | 9809859 |
C056895 | flesinoxan | flesinoxan binds to and results in increased activity of HTR1A protein | 9548383 |
C056895 | flesinoxan | flesinoxan binds to and results in increased activity of HTR1A protein | 7906241 |
D005473 | Fluoxetine | Fluoxetine results in decreased expression of HTR1A mRNA | 17761399 |
D005473 | Fluoxetine | Fluoxetine inhibits the reaction [IFNA1 protein results in decreased expression of HTR1A mRNA] | 15885359 |
D005473 | Fluoxetine | Fluoxetine inhibits the reaction [IFNA1 protein results in decreased expression of HTR1A protein] | 15885359 |
D005473 | Fluoxetine | HTR1A gene polymorphism results in increased susceptibility to Fluoxetine | 16302021 |
D005473 | Fluoxetine | HTR1A promoter polymorphism affects the susceptibility to Fluoxetine | 16458487 |
D005473 | Fluoxetine | HTR1A protein results in increased susceptibility to Fluoxetine | 16302021|1645848 |
D005473 | Fluoxetine | Fluoxetine results in increased expression of HTR1A mRNA | 21083617 |
D005473 | Fluoxetine | [Fluoxetine co-treated with Venlafaxine Hydrochloride co-treated with Carbamazepine] results in decreased expression of HTR1A mRNA | 22701549 |
D005473 | Fluoxetine | Fluoxetine affects the expression of HTR1A | 26475043 |
D005473 | Fluoxetine | Fluoxetine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] | 10665824 |
D005473 | Fluoxetine | Fluoxetine inhibits the reaction [HTR1A protein results in increased uptake of Serotonin] | 11106871 |
D005473 | Fluoxetine | Fluoxetine results in decreased expression of HTR1A mRNA | 10665824 |
D005473 | Fluoxetine | HTR1A protein results in increased susceptibility to Fluoxetine | 18573488 |
D005473 | Fluoxetine | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [HTR1A protein results in increased susceptibility to Fluoxetine] | 18573488 |
D005473 | Fluoxetine | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide promotes the reaction [Fluoxetine inhibits the reaction [HTR1A protein results in increased uptake of Serotonin]] | 11106871 |
C039979 | gepirone | gepirone binds to and results in increased activity of HTR1A protein | 11070179|1122049 |
C119994 | GR 46611 | GR 46611 binds to HTR1A protein | 15152026 |
D006153 | Guanosine Diphosphate | Guanosine Diphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
D006160 | Guanosine Triphosphate | Guanosine Triphosphate affects the reaction [Serotonin binds to HTR1A protein] | 21126535 |
D006160 | Guanosine Triphosphate | Guanosine Triphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
D006160 | Guanosine Triphosphate | Manganese inhibits the reaction [Guanosine Triphosphate affects the reaction [Serotonin binds to HTR1A protein]] | 21126535 |
D012701 | Serotonin | Serotonin binds to and affects the activity of HTR1A protein | 17202474 |
D012701 | Serotonin | Serotonin results in increased expression of HTR1A mRNA | 21083617 |
D012701 | Serotonin | [1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Serotonin | 16528294 |
D012701 | Serotonin | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in increased susceptibility to Serotonin | 16528294 |
D012701 | Serotonin | Fluoxetine inhibits the reaction [HTR1A protein results in increased uptake of Serotonin] | 11106871 |
D012701 | Serotonin | Guanosine Diphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
D012701 | Serotonin | Guanosine Triphosphate affects the reaction [Serotonin binds to HTR1A protein] | 21126535 |
D012701 | Serotonin | Guanosine Triphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
D012701 | Serotonin | HTR1A protein affects the susceptibility to Serotonin | 16528294 |
D012701 | Serotonin | HTR1A protein results in increased uptake of Serotonin | 11106871 |
D012701 | Serotonin | Magnesium affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
D012701 | Serotonin | Manganese affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
D012701 | Serotonin | Manganese inhibits the reaction [Guanosine Triphosphate affects the reaction [Serotonin binds to HTR1A protein]] | 21126535 |
D012701 | Serotonin | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide promotes the reaction [Fluoxetine inhibits the reaction [HTR1A protein results in increased uptake of Serotonin]] | 11106871 |
D012701 | Serotonin | Serotonin binds to HTR1A protein | 21126535 |
D012701 | Serotonin | Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein] | 21126535 |
D012701 | Serotonin | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in decreased activity of HTR1A protein] inhibits the reaction [Serotonin results in decreased susceptibility to Pilocarpine] | 15140183 |
D017367 | Serotonin Uptake Inhibitors | HTR1A gene polymorphism affects the susceptibility to Serotonin Uptake Inhibitors | 19800133 |
D017367 | Serotonin Uptake Inhibitors | Serotonin Uptake Inhibitors results in decreased activity of HTR1A protein | 22265196 |
C062018 | HU 211 | HU 211 results in increased activity of HTR1A protein | 20438810 |
C062018 | HU 211 | HU 211 results in increased expression of HTR1A mRNA | 20438810 |
D007099 | Imipramine | Imipramine affects the expression of HTR1A mRNA | 17617388 |
C043077 | ipsapirone | ipsapirone binds to and results in increased activity of HTR1A protein | 9163561 |
C043077 | ipsapirone | ipsapirone binds to and results in increased activity of HTR1A protein | 14767715 |
C043077 | ipsapirone | ipsapirone binds to and results in increased activity of HTR1A protein | 12398907|2250574 |
C554161 | JB-788 | JB-788 binds to and results in increased activity of HTR1A protein | 20580787 |
C554161 | JB-788 | [JB-788 binds to and results in increased activity of HTR1A protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP] | 20580787 |
D008070 | Lipopolysaccharides | HTR1A protein affects the susceptibility to Lipopolysaccharides | 12479973 |
D008152 | Loxapine | Loxapine analog binds to HTR1A protein | 9723970 |
D008152 | Loxapine | Loxapine binds to HTR1A protein | 9723970 |
D000069056 | Lurasidone Hydrochloride | Lurasidone Hydrochloride binds to and results in increased activity of HTR1A protein | 20404009 |
D008274 | Magnesium | Magnesium affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
D008345 | Manganese | Manganese affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
D008345 | Manganese | Manganese inhibits the reaction [Guanosine Triphosphate affects the reaction [Serotonin binds to HTR1A protein]] | 21126535 |
C085838 | MDL 75608A | MDL 75608A binds to and results in increased activity of HTR1A protein | 7906241 |
D017258 | Medroxyprogesterone Acetate | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of HTR1A mRNA | 20823114 |
D008555 | Melitten | Melitten inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] | 11356925 |
C014655 | methamidophos | methamidophos affects the activity of HTR1A protein | 23596261 |
C014655 | methamidophos | methamidophos inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 21871486 |
D008694 | Methamphetamine | HTR1A gene SNP results in increased susceptibility to Methamphetamine | 19747927 |
D008694 | Methamphetamine | [1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine | 15213358 |
D008719 | Methiothepin | Methiothepin binds to and results in decreased activity of HTR1A protein | 15482641 |
D008719 | Methiothepin | Methiothepin binds to and results in decreased activity of HTR1A protein | 2207497 |
D003189 | p-Methoxy-N-methylphenethylamine | p-Methoxy-N-methylphenethylamine results in increased activity of HTR1A protein | 16415902 |
C035133 | mirtazapine | mirtazapine binds to and results in increased activity of HTR1A protein | 12897636|1651187 |
D009020 | Morphine | 4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine] | 10640309 |
D009020 | Morphine | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine | 10640309 |
C518313 | N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine | "N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine binds to and results in increased activity of HTR1A protein" | 17300168 |
C518313 | N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine | "N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine binds to and results in increased activity of HTR1A protein" | 19695244 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein | 9163561 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide analog binds to HTR1A protein | 21520940 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide analog inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] | 21520940 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein | 15482641 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein | 15136721|1641508 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased activity of DDC protein | 16415089 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | Guanosine Diphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | Guanosine Triphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | Magnesium affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | Manganese affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]] | 21126535 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and affects the activity of HTR1A protein | 9809859 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein | 12589378|1599656 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | "[N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-((5-(4-fluorophenyl)-3-pyridinyl)methyl)piperazine" | 15996562 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to bifeprunox | 15996562 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to sarizotan | 15996562 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to ziprasidone | 15996562 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein | 21126535 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [[4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine Hydrobromide] | 10578133 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [HTR1A protein results in increased susceptibility to 8-hydroxy-2-(N-n-propyl-N-(3'-iodo-2'-propenyl)amino)tetralin] | 18573488 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [HTR1A protein results in increased susceptibility to Fluoxetine] | 18573488 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [HTR1A protein results in increased susceptibility to Risperidone] | 17530476 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide promotes the reaction [Fluoxetine inhibits the reaction [HTR1A protein results in increased uptake of Serotonin]] | 11106871 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | [[Remoxipride results in decreased activity of DRD2 protein] co-treated with [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in decreased activity of HTR1A protein]] results in increased susceptibility to Pilocarpine | 15140183 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein] | 21126535 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein | 10771018|1107017 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Nicotine | 10771018 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in decreased activity of HTR1A protein | 11220492|1514018 |
C090413 | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in decreased activity of HTR1A protein] inhibits the reaction [Serotonin results in decreased susceptibility to Pilocarpine] | 15140183 |
C518644 | N-(4-(4-(3-aminocarbonyl-phenyl)-piperazin-1-yl)-butyl)-4-bromo-benzamide | N-(4-(4-(3-aminocarbonyl-phenyl)-piperazin-1-yl)-butyl)-4-bromo-benzamide binds to HTR1A protein | 17170312 |
D000068577 | Nebivolol | Nebivolol binds to HTR1A protein | 2462161 |
D000068577 | Nebivolol | Nebivolol inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 2462161 |
C051752 | nefazodone | nefazodone binds to HTR1A protein | 7855217 |
D009538 | Nicotine | Nicotine results in decreased expression of HTR1A protein | 21324836 |
D009538 | Nicotine | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Nicotine | 10771018 |
C055895 | N,N-dipropylcarboxamidotryptamine | "N,N-dipropylcarboxamidotryptamine binds to and results in increased activity of HTR1A protein" | 15482641 |
D009277 | Nandrolone | [testosterone 17 beta-cypionate co-treated with Nandrolone co-treated with testosterone undecanoate] results in decreased expression of HTR1A protein | 16914188 |
C561226 | N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate | "N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate binds to and results in increased activity of HTR1A protein" | 21591752 |
C106996 | NRA 0045 | NRA 0045 binds to HTR1A protein | 9223539 |
C025589 | ochratoxin A | ochratoxin A results in increased expression of HTR1A mRNA | 27346841 |
D016627 | Oxidopamine | Oxidopamine results in decreased expression of HTR1A mRNA | 18707801 |
D016627 | Oxidopamine | stepholidine inhibits the reaction [Oxidopamine results in decreased expression of HTR1A mRNA] | 18707801 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein | 9163561 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein | 14767715|1548264 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide analog inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] | 21520940 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein | 21871486 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | methamidophos inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 21871486 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine] | 10640309 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | "8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]" | 11927170 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and affects the activity of HTR1A protein | 9809859 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of OXT protein modified form | 22265196 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of POMC protein modified form | 22265196 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein | 10665824|1259122 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine | 8539317 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine | 8539317 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine | 10640309 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine | 8539317 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in increased susceptibility to Serotonin | 16528294 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein | 11927170|1476771 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein | 18622176 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] which results in decreased susceptibility to Pilocarpine | 2533336 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Cocaine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 9723786 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Diazinon promotes the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 17035140 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Estradiol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of OXT protein modified form] | 22265196 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Estradiol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of POMC protein modified form] | 22265196 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Fluoxetine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] | 10665824 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Parathion inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 17035140 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] | 18622176 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] | 8539317 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] | 8539317 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein | 22265196 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein | 10640309|1066990 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein | 22029386|2462161 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein | 2533336 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | carvedilol inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 2462161 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Nebivolol inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 2462161 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Pindolol inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 2462161 |
D017371 | 8-Hydroxy-2-(di-n-propylamino)tetralin | Propranolol inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 2462161 |
C096294 | osemozotan | osemozotan binds to and results in increased activity of HTR1A protein | 16952156 |
D010278 | Parathion | Parathion affects the expression of HTR1A protein | 18773955 |
D010278 | Parathion | Parathion inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 17035140 |
D010278 | Parathion | Parathion results in decreased expression of HTR1A protein | 17035140|1961608 |
D010278 | Parathion | Parathion results in increased expression of HTR1A protein | 19616088 |
C480679 | pardoprunox | pardoprunox binds to and results in increased activity of HTR1A protein | 21591752 |
D010703 | Phorbol Esters | Phorbol Esters results in decreased activity of HTR1A protein | 11356925 |
D010830 | Physostigmine | [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine | 8539317 |
D010830 | Physostigmine | [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine | 8539317 |
D010830 | Physostigmine | tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] | 8539317 |
D010830 | Physostigmine | tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] | 8539317 |
C510463 | Piclozotan | Piclozotan binds to and results in increased activity of HTR1A protein | 22029386 |
D010862 | Pilocarpine | [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] which results in decreased susceptibility to Pilocarpine | 2533336 |
D010862 | Pilocarpine | [[Remoxipride results in decreased activity of DRD2 protein] co-treated with [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in decreased activity of HTR1A protein]] results in increased susceptibility to Pilocarpine | 15140183 |
D010862 | Pilocarpine | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in decreased activity of HTR1A protein] inhibits the reaction [Serotonin results in decreased susceptibility to Pilocarpine] | 15140183 |
D010869 | Pindolol | Pindolol inhibits the reaction [flesinoxan binds to and results in increased activity of HTR1A protein] | 9163561 |
D010869 | Pindolol | Pindolol binds to and affects the activity of HTR1A protein | 9809859 |
D010869 | Pindolol | Pindolol binds to and results in decreased activity of HTR1A protein | 2207497 |
D010869 | Pindolol | Pindolol binds to and results in decreased activity of HTR1A protein | 15542624|8386235 |
D010869 | Pindolol | Pindolol binds to HTR1A protein | 2462161 |
D010869 | Pindolol | Pindolol inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 2462161 |
D011433 | Propranolol | Propranolol binds to HTR1A protein | 2462161 |
D011433 | Propranolol | Propranolol inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] | 2462161 |
D011814 | Quipazine | Quipazine binds to and affects the activity of HTR1A protein | 15482641 |
D017330 | Remoxipride | [[Remoxipride results in decreased activity of DRD2 protein] co-treated with [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in decreased activity of HTR1A protein]] results in increased susceptibility to Pilocarpine | 15140183 |
C111221 | repinotan hydrochloride | repinotan hydrochloride binds to and results in increased activity of HTR1A protein | 20802053|2202938 |
D012110 | Reserpine | Reserpine results in decreased expression of HTR1A protein | 26114099 |
D018967 | Risperidone | HTR1A protein results in increased susceptibility to Risperidone | 17530476 |
D018967 | Risperidone | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [HTR1A protein results in increased susceptibility to Risperidone] | 17530476 |
C108607 | robalzotan | robalzotan binds to and results in decreased activity of HTR1A protein | 12589378 |
C443959 | sarizotan | sarizotan binds to and results in increased activity of HTR1A protein | 14767715 |
C443959 | sarizotan | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to sarizotan | 15996562 |
C443959 | sarizotan | sarizotan binds to HTR1A protein | 14767715 |
C443959 | sarizotan | sarizotan binds to and results in increased activity of HTR1A protein | 11723272|1461494 |
D012601 | Scopolamine Hydrobromide | [4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine Hydrobromide | 10578133 |
D012601 | Scopolamine Hydrobromide | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [[4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine Hydrobromide] | 10578133 |
D020280 | Sertraline | [Estradiol co-treated with Sertraline] affects the expression of HTR1A mRNA | 18650020 |
D020280 | Sertraline | Sertraline results in increased expression of HTR1A mRNA | 18650020 |
C017947 | sodium arsenite | sodium arsenite results in decreased expression of HTR1A mRNA | 25128769 |
D012999 | Soman | Soman results in decreased expression of HTR1A mRNA | 19281266 |
D013134 | Spiperone | Spiperone binds to and results in decreased activity of HTR1A protein | 15482641 |
D013134 | Spiperone | Spiperone binds to and results in decreased activity of HTR1A protein | 2207497 |
C010513 | stepholidine | stepholidine binds to and results in increased activity of HTR1A protein | 18707801 |
C010513 | stepholidine | stepholidine inhibits the reaction [Oxidopamine results in decreased expression of HTR1A mRNA] | 18707801 |
D013311 | Streptozocin | Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] | 18622176 |
D014284 | Triiodothyronine | Triiodothyronine results in increased expression of HTR1A mRNA | 17403546 |
C055267 | tandospirone | tandospirone binds to and results in increased activity of HTR1A protein | 11070179|1188975 |
C518393 | technetium 99m tricarbonyl 4-((2-methoxyphenyl)piperazin-1-yl)dithioformate | technetium 99m tricarbonyl 4-((2-methoxyphenyl)piperazin-1-yl)dithioformate binds to HTR1A protein | 17074495 |
C005632 | tertatolol | tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] | 8539317 |
C005632 | tertatolol | tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] | 8539317 |
C005632 | tertatolol | tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] | 8539317 |
C005632 | tertatolol | tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] | 8539317 |
C016131 | testosterone 17 beta-cypionate | [testosterone 17 beta-cypionate co-treated with Nandrolone co-treated with testosterone undecanoate] results in decreased expression of HTR1A protein | 16914188 |
C010792 | testosterone undecanoate | [testosterone 17 beta-cypionate co-treated with Nandrolone co-treated with testosterone undecanoate] results in decreased expression of HTR1A protein | 16914188 |
D019284 | Thapsigargin | Thapsigargin results in increased activity of HTR1A protein | 11356925 |
D013974 | Thyroxine | Thyroxine results in increased expression of HTR1A mRNA | 17403546 |
D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in decreased expression of HTR1A protein | 27633979 |
D014196 | Trazodone | Trazodone binds to HTR1A protein | 7855217 |
D014196 | Trazodone | Trazodone results in decreased expression of HTR1A protein | 12127910 |
D014196 | Trazodone | Trazodone results in increased expression of HTR1A protein | 1589591 |
D014196 | Trazodone | Trazodone binds to HTR1A protein | 19711746 |
D014302 | Trinitrobenzenesulfonic Acid | Trinitrobenzenesulfonic Acid results in increased expression of HTR1A mRNA | 23537331 |
C064282 | UH 301 | UH 301 inhibits the reaction [flesinoxan binds to and results in increased activity of HTR1A protein] | 9163561 |
C015568 | urapidil | urapidil binds to and results in increased activity of HTR1A protein | 9829161 |
D001335 | Vehicle Emissions | Vehicle Emissions results in decreased methylation of HTR1A gene | 25560391 |
D000069470 | Venlafaxine Hydrochloride | [Fluoxetine co-treated with Venlafaxine Hydrochloride co-treated with Carbamazepine] results in decreased expression of HTR1A mRNA | 22701549 |
C557874 | vortioxetine | vortioxetine binds to and results in increased activity of HTR1A protein | 21486038 |
C081293 | WAY 100135 | WAY 100135 inhibits the reaction [flesinoxan binds to and results in increased activity of HTR1A protein] | 9163561 |
C081293 | WAY 100135 | WAY 100135 binds to and results in decreased activity of HTR1A protein | 16047547|1858539 |
C081293 | WAY 100135 | WAY 100135 binds to and results in increased activity of HTR1A protein | 12398907 |
C092292 | ziprasidone | [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to ziprasidone | 15996562 |
C092292 | ziprasidone | ziprasidone binds to HTR1A protein | 7562537 |