Gene: APOB

338
FLDB|LDLCQ4|apoB-100|apoB-48
apolipoprotein B
protein-coding
2p24.1
Ensembl:ENSG00000084674 MIM:107730 Vega:OTTHUMG00000090785 UniprotKB:P04114
NG_011793.1
PubMed
0   ANCO-SNPs
ND|AD
213   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.982e-2 (AD)  2.268e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CCL280.529
ZDHHC150.497
FARP20.496
RFC30.489
ZW100.486
ZNF7820.486
PYROXD10.485
NUP1550.482
USP6NL0.48
CCDC680.478

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RLBP1-0.292
EMX2-0.278
PPP1R3G-0.275
TLCD1-0.271
S100A1-0.27
OAF-0.269
PLA2G5-0.266
PIPOX-0.264
PPP1R3C-0.263
SLC9A3R1-0.262

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0364231-aminomethylphosphonic acid"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APOB mRNA"20566314
C0364231-aminomethylphosphonic acid[Herbicides co-treated with 1-aminomethylphosphonic acid] results in decreased expression of APOB mRNA20566314
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of APOB mRNA"25614096
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of APOB mRNA"16488489
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of APOB mRNA"23962555
C0467282,2'-azobis(2-amidinopropane)"2,2'-azobis(2-amidinopropane) results in increased metabolism of APOB protein"14670006
C0467282,2'-azobis(2-amidinopropane)"7,8-dihydroneopterin inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased metabolism of APOB protein]"14670006
C0467282,2'-azobis(2-amidinopropane)"alpha-Tocopherol inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased metabolism of APOB protein]"14670006
C0164032,4-dinitrotoluene"2,4-dinitrotoluene results in decreased expression of APOB mRNA"16917068
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of APOB mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in decreased expression of APOB mRNA"20406850
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of APOB mRNA"21346803
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in decreased expression of APOB mRNA"16192472
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of APOB mRNA"28973532
C0182583-deazaadenosine[3-deazaadenosine co-treated with Ethanolamine] results in decreased secretion of APOB protein alternative form8944747
C4711094(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline"4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline results in decreased secretion of APOB protein"19342510
C4711094(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline"acetylleucyl-leucyl-norleucinal inhibits the reaction [4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline results in decreased secretion of APOB protein]"19342510
C4711094(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline"4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [Fructose results in increased expression of APOB protein]"19342510
C4711094(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline"4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline results in decreased expression of APOB protein"19342510
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of APOB mRNA"27188386
C0415944-nonylphenol4-nonylphenol results in decreased expression of APOB mRNA17912697
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of APOB mRNA"27188386
C0009767,8-dihydroneopterin"7,8-dihydroneopterin inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased metabolism of APOB protein]"14670006
C0009767,8-dihydroneopterin"7,8-dihydroneopterin inhibits the reaction [Copper results in increased metabolism of APOB protein]"14670006
D000082AcetaminophenAcetaminophen results in decreased expression of APOB mRNA21420995|2649742
C031800acetic anhydride[Sodium Acetate co-treated with acetic anhydride] results in increased acetylation of APOB protein11304478
C043377acetochlor"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APOB mRNA"20566314
C063261acetylleucyl-leucyl-norleucinal"acetylleucyl-leucyl-norleucinal inhibits the reaction [4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline results in decreased secretion of APOB protein]"19342510
C063261acetylleucyl-leucyl-norleucinalacetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]19383982
C063261acetylleucyl-leucyl-norleucinalacetylleucyl-leucyl-norleucinal inhibits the reaction [lactacystin results in decreased expression of and results in decreased secretion of APOB protein]19383982
C063261acetylleucyl-leucyl-norleucinalacetylleucyl-leucyl-norleucinal results in increased expression of and results in increased secretion of APOB protein19383982
D020106AcrylamideAcrylamide results in decreased expression of APOB mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 affects the expression of APOB protein20106945
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of APOB mRNA28522335
D024502alpha-Tocopherolalpha-Tocopherol promotes the reaction [APOB protein results in increased reduction of Copper]11368321
D024502alpha-Tocopherol"alpha-Tocopherol inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased metabolism of APOB protein]"14670006
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Copper results in increased metabolism of APOB protein]14670006
D000535AluminumAluminum results in increased expression of APOB protein17762189
D019856Ethanolamine[3-deazaadenosine co-treated with Ethanolamine] results in decreased secretion of APOB protein alternative form8944747
D019856Ethanolamine[Bezafibrate co-treated with Ethanolamine] results in decreased secretion of APOB protein alternative form8944747
D019856Ethanolamine[Clofibric Acid co-treated with Ethanolamine] results in decreased secretion of APOB protein alternative form8944747
D000638AmiodaroneAmiodarone results in decreased expression of APOB mRNA29248575
D000643Ammonium ChlorideAmmonium Chloride affects the expression of APOB mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of APOB mRNA24449571
D001205Ascorbic AcidAscorbic Acid promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D001205Ascorbic AcidAscorbic Acid promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D001205Ascorbic Acid[Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOB mRNA17639512
D001262AtenololAtenolol results in increased expression of APOB1928808
D001262AtenololAtenolol results in increased expression of APOB protein2193493
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased expression of and results in decreased secretion of APOB protein12612140
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased expression of APOB protein12172771|1263379
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased secretion of APOB protein10357840|1172839
D000069059Atorvastatin CalciumAtorvastatin Calcium inhibits the reaction [Fructose results in increased expression of APOB protein]12065722
C044946benazeprilfluvastatin promotes the reaction [[Valsartan co-treated with benazepril] results in decreased expression of APOB protein]20671225
C044946benazepril[Valsartan co-treated with benazepril] results in decreased expression of APOB protein20671225
D001539BendroflumethiazideBendroflumethiazide affects the expression of APOB protein2344503
D001554BenzeneBenzene results in increased expression of APOB mRNA15878777
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in decreased expression of APOB mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of APOB mRNA20106945|2163298
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of APOB mRNA"26238291
D004958EstradiolEstradiol results in decreased expression of APOB mRNA17912697
D004958EstradiolEstradiol results in increased stability of APOB protein11076531
D004958EstradiolEstradiol results in decreased expression of APOB mRNA16192472
D004958EstradiolEstradiol results in increased expression of APOB mRNA21984479
C095105bexarotenebexarotene results in decreased expression of APOB mRNA16648578
D001629BezafibrateBezafibrate inhibits the reaction [Oleic Acid results in increased expression of APOB protein]12048068
D001629BezafibrateBezafibrate results in decreased expression of APOB protein1323073|3084275|
D001629BezafibrateBezafibrate results in decreased secretion of APOB protein21640707
D001629BezafibrateBezafibrate results in decreased expression of APOB mRNA alternative form12782154
D001629BezafibratePPARA protein affects the reaction [Bezafibrate results in decreased expression of APOB mRNA alternative form]12782154
D001629BezafibratePPARD protein affects the reaction [Bezafibrate results in decreased expression of APOB mRNA alternative form]12782154
D001629Bezafibrate[Bezafibrate co-treated with Ethanolamine] results in decreased secretion of APOB protein alternative form8944747
D001629BezafibrateBezafibrate results in increased expression of APOB protein9006809
C006780bisphenol Abisphenol A results in decreased expression of APOB mRNA17912697
C006780bisphenol Abisphenol A results in increased expression of APOB mRNA28483554
C006780bisphenol Abisphenol A results in increased expression of APOB mRNA28483554
C006780bisphenol Abisphenol A results in decreased expression of APOB mRNA23399309|2518105
C006780bisphenol A[bisphenol A results in decreased expression of APOB mRNA] which affects the abundance of Triglycerides23399309
C006780bisphenol Abisphenol A results in increased expression of APOB mRNA17010207
C006780bisphenol Awortmannin inhibits the reaction [bisphenol A results in decreased expression of APOB mRNA]23399309
C006780bisphenol Awortmannin inhibits the reaction [[bisphenol A results in decreased expression of APOB mRNA] which results in decreased abundance of Triglycerides]23399309
C006780bisphenol Abisphenol A results in decreased expression of APOB mRNA26794494
D002065BuspironeBuspirone results in decreased expression of APOB mRNA24136188
D002104CadmiumAPOB protein binds to Cadmium23896426
D002110Caffeine[Ephedrine co-treated with Caffeine] results in decreased expression of APOB protein16324916
D002110CaffeineCaffeine results in decreased expression of APOB mRNA25868845
D000074262Canola OilCanola Oil results in decreased expression of APOB protein alternative form16631440
D002211CapsaicinCapsaicin results in increased expression of APOB mRNA16278290
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of APOB protein17405876
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of APOB mRNA15963342
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of APOB mRNA16644059|1922454
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of APOB mRNA24763279
D002509CephaloridineCephaloridine results in increased expression of APOB mRNA18500788
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of APOB mRNA18178546
D002784CholesterolCholesterol results in increased expression of APOB protein16271152|1658104
D002784CholesterolSelenium inhibits the reaction [Cholesterol results in increased expression of APOB protein]16581047
D002793Cholic Acids[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of APOB mRNA27344345
D002794Choline"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of APOB mRNA"28973532
D002794Choline[Choline deficiency co-treated with Methionine deficiency] results in increased expression of APOB mRNA25178843
D002794CholineCholine deficiency results in increased expression of APOB mRNA25178843
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of APOB mRNA28973532
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of APOB mRNA28472532
C553724ciklavitciklavit inhibits the reaction [Dietary Fats results in decreased expression of APOB protein]23287313
D002994ClofibrateClofibrate results in decreased expression of APOB mRNA16081524
D002994ClofibrateClofibrate results in decreased expression of APOB protein20573577
D002995Clofibric Acid[Clofibric Acid co-treated with Ethanolamine] results in decreased secretion of APOB protein alternative form8944747
C018021cobaltous chloridecobaltous chloride results in decreased expression of APOB mRNA24386269
D003300Copperalpha-Tocopherol promotes the reaction [APOB protein results in increased reduction of Copper]11368321
D003300CopperAPOB protein binds to Copper23896426
D003300CopperAPOB protein results in increased reduction of Copper11368321
D003300CopperAscorbic Acid promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D003300CopperAscorbic Acid promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D003300CopperCopper results in increased oxidation of APOB protein17475462
D003300CopperFlavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]17475462
D003300CopperQuercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]17475462
D003300CopperVitamin E promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D003300CopperVitamin E promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D003300Copper[Fructose co-treated with Copper deficiency] results in decreased expression of APOB mRNA25813056
D003300Coppergadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of APOB mRNA]25813056
D003300Copper"7,8-dihydroneopterin inhibits the reaction [Copper results in increased metabolism of APOB protein]"14670006
D003300Copperalpha-Tocopherol inhibits the reaction [Copper results in increased metabolism of APOB protein]14670006
D003300CopperCopper results in increased metabolism of APOB protein14670006
D019327Copper SulfateCopper Sulfate results in decreased expression of APOB mRNA19549813
D019327Copper SulfateCopper Sulfate results in increased cleavage of APOB protein19489629
D019327Copper SulfateGlucose promotes the reaction [Copper Sulfate results in increased cleavage of APOB protein]19489629
C029892cupric chloridecupric chloride results in increased expression of APOB mRNA21072851
C029892cupric chloridecupric chloride results in decreased expression of APOB protein19616320
C057862cyanoginosin LRcyanoginosin LR affects the expression of APOB protein26984711
D003520CyclophosphamideCyclophosphamide results in decreased expression of APOB mRNA18246545
D016572CyclosporineCyclosporine results in decreased expression of APOB mRNA20106945|2556210
D016572CyclosporineCyclosporine results in decreased expression of APOB mRNA19770486
D016572CyclosporineCyclosporine results in decreased expression of APOB mRNA19224547
C017160cypermethrincypermethrin results in increased expression of APOB mRNA9650644
D0150842,4-Dichlorophenoxyacetic Acid"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APOB mRNA"20566314
D003630DaunorubicinDaunorubicin results in increased expression of APOB protein7637207
D003907DexamethasoneDexamethasone results in increased expression of APOB protein15965953
D002945CisplatinCisplatin results in increased expression of APOB protein22023808
C000944dicrotophosdicrotophos results in increased expression of APOB mRNA28302478
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of APOB mRNA26924002
D004026DieldrinDieldrin results in increased expression of APOB mRNA28385952
D004041Dietary Fatsciklavit inhibits the reaction [Dietary Fats results in decreased expression of APOB protein]23287313
D004041Dietary FatsDietary Fats results in decreased expression of APOB protein23287313
D004041Dietary FatsDietary Fats results in increased expression of APOB protein18166149
D004041Dietary FatsFenofibrate inhibits the reaction [Dietary Fats results in increased expression of APOB protein]18166149
D004041Dietary Fatsgamma-sitosterol inhibits the reaction [Dietary Fats results in decreased expression of APOB protein]23287313
D004041Dietary Fatsresveratrol inhibits the reaction [Dietary Fats results in increased expression of APOB protein]18166149
C007379diethyl phthalatediethyl phthalate results in increased degradation of APOB protein26423653
D004047Diethyl PyrocarbonateDiethyl Pyrocarbonate results in increased metabolism of APOB protein11304478
D004281Docosahexaenoic Acids[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein17237316
D004317DoxorubicinDoxorubicin results in increased expression of APOB protein8255516|8506949
D015118Eicosapentaenoic Acid[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein17237316
D004785Environmental PollutantsEnvironmental Pollutants results in decreased expression of APOB protein22085608
D004785Environmental PollutantsEnvironmental Pollutants results in decreased expression of APOB mRNA24534155
D004785Environmental PollutantsEnvironmental Pollutants results in increased expression of APOB mRNA20064776
D004809Ephedrine[Ephedrine co-treated with Caffeine] results in decreased expression of APOB protein16324916
D000431Ethanol[Ethanol co-treated with Zinc] results in increased expression of APOB mRNA19637192
D000431Ethanol[Zinc deficiency co-treated with Ethanol] affects the expression of APOB mRNA24155903
D000431EthanolEthanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA]26854922
D000431EthanolEthanol results in increased expression of APOB mRNA16946407
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of APOB mRNA17912697
D004997Ethinyl Estradiol[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of APOB protein15769986
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of APOB mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of APOB mRNA16488489
D011345FenofibrateFenofibrate results in decreased expression of APOB protein21411093
D011345FenofibrateFenofibrate inhibits the reaction [Dietary Fats results in increased expression of APOB protein]18166149
C004999ferulic acidferulic acid results in decreased expression of APOB protein20573577
D005419FlavonoidsAscorbic Acid promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D005419FlavonoidsFlavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]17475462
D005419FlavonoidsVitamin E promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D005485FlutamideFlutamide results in decreased expression of APOB mRNA24793618
C065180fluvastatin[APOB gene SNP co-treated with APOE gene SNP co-treated with HMGCR gene SNP co-treated with LDLR gene SNP co-treated with PCSK9 gene SNP co-treated with ABCA1 gene SNP co-treated with CETP gene SNP co-treated with LIPC gene SNP co-treated with LPL gene SNP] affects the susceptibility to fluvastatin19773416
C065180fluvastatinfluvastatin promotes the reaction [[Valsartan co-treated with benazepril] results in decreased expression of APOB protein]20671225
D005492Folic Acid[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein17237316
D005492Folic AcidFolic Acid results in increased expression of APOB mRNA17868486
D005492Folic Acid[APOE gene mutant form affects the susceptibility to Folic Acid] which results in decreased expression of APOB protein17118406
D005632Fructose"4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [Fructose results in increased expression of APOB protein]"19342510
D005632FructoseFructose results in increased expression of APOB protein19342510
D005632Fructose[FGF21 gene mutant form results in increased susceptibility to Fructose] which results in decreased expression of APOB mRNA28123933
D005632FructoseFructose results in increased expression of APOB protein27531227
D005632FructosePlant Preparations inhibits the reaction [Fructose results in increased expression of APOB protein]27531227
D005632FructoseAtorvastatin Calcium inhibits the reaction [Fructose results in increased expression of APOB protein]12065722
D005632Fructose[Fructose co-treated with Copper deficiency] results in decreased expression of APOB mRNA25813056
D005632FructoseFructose results in increased expression of APOB mRNA8415773
D005632FructoseFructose results in increased expression of APOB protein12065722|8415773
D005632Fructosegadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of APOB mRNA]25813056
C038958gadolinium chloridegadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of APOB mRNA]25813056
D005707Gallic AcidGallic Acid results in decreased secretion of APOB protein12612140
C025473gamma-sitosterolgamma-sitosterol inhibits the reaction [Dietary Fats results in decreased expression of APOB protein]23287313
D015248GemfibrozilGemfibrozil results in decreased expression of APOB protein11701466
D015248GemfibrozilGemfibrozil results in decreased expression of APOB protein9006809
D019833GenisteinGenistein results in increased expression of APOB mRNA17010207
D019833GenisteinGenistein results in increased expression of APOB protein24552547
D005839GentamicinsGentamicins results in decreased expression of APOB mRNA22061828
D005944GlucosamineGlucosamine results in increased degradation of APOB protein15618547
D005944GlucosamineOleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein]15618547
D005944Glucosamineacetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]19383982
D005944GlucosamineGlucosamine results in decreased expression of and results in decreased secretion of APOB protein19383982
D005944GlucosamineGlucosamine results in decreased expression of APOB protein15618547
D005944GlucosamineGlucosamine results in decreased localization of APOB protein15618547
D005944GlucosamineGlucosamine results in decreased secretion of APOB protein15618547
D005944GlucosamineGlucosamine results in increased ubiquitination of APOB protein15618547
D005944GlucosamineOleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]15618547
D005944GlucosamineGlucosamine results in increased degradation of APOB protein15618547
D005944GlucosamineOleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein]15618547
D005947GlucoseGlucose promotes the reaction [Copper Sulfate results in increased cleavage of APOB protein]19489629
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of APOB mRNA24763279
C412815GW 4064GW 4064 results in increased expression of APOB mRNA26655953
D006540Herbicides"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APOB mRNA"20566314
D006540Herbicides[Herbicides co-treated with 1-aminomethylphosphonic acid] results in decreased expression of APOB mRNA20566314
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of APOB mRNA20044591
D002112CalcifediolCalcifediol deficiency results in decreased expression of APOB mRNA17293106
C016517indole-3-carbinolindole-3-carbinol results in decreased expression of APOB mRNA16192472
C081309irbesartanAPOB gene SNP affects the susceptibility to irbesartan15453913|1561402
C051140iron(II)-ascorbic acid complexiron(II)-ascorbic acid complex results in decreased expression of APOB protein10898742
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of APOB mRNA15618438
C067713lactacystinacetylleucyl-leucyl-norleucinal inhibits the reaction [lactacystin results in decreased expression of and results in decreased secretion of APOB protein]19383982
C067713lactacystinHSPA5 promotes the reaction [lactacystin results in increased expression of APOB protein]15618547
C067713lactacystinHSPA5 promotes the reaction [lactacystin results in increased secretion of APOB protein]15618547
C067713lactacystinlactacystin inhibits the reaction [HSPA5 results in increased degradation of APOB protein]15618547
C067713lactacystinlactacystin results in increased expression of and results in increased secretion of APOB protein19383982
C067713lactacystinlactacystin results in increased expression of APOB protein15618547
C067713lactacystinlactacystin results in increased secretion of APOB protein15618547
D001556LindaneLindane affects the expression of APOB mRNA17785943
C002385linsidominelinsidomine results in increased oxidation of APOB protein28086193
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of APOB mRNA"24972896
C558899lopinavir-ritonavir drug combinationlopinavir-ritonavir drug combination results in increased expression of APOB protein12646808
D008148LovastatinLovastatin results in decreased secretion of APOB protein11728391
D008148Lovastatin[Niacin co-treated with Lovastatin] results in decreased expression of APOB protein12633795
D008383MargarineMargarine results in increased expression of APOB protein alternative form16631440
C008340mecoprop"[Herbicides co-treated with 1-aminomethylphosphonic acid co-treated with mecoprop co-treated with acetochlor co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APOB mRNA"20566314
D008627Mercuric ChlorideMercuric Chloride affects the expression of APOB mRNA20353558
D008715Methionine"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of APOB mRNA"28973532
D008715Methionine[Choline deficiency co-treated with Methionine deficiency] results in increased expression of APOB mRNA25178843
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of APOB mRNA28973532
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of APOB mRNA23179753
C043243methyl tert-butyl ethermethyl tert-butyl ether affects the expression of APOB mRNA24128854
C524142mipomersenmipomersen results in decreased expression of APOB protein19071883
C517284monomethyl phthalatemonomethyl phthalate affects the expression of APOB mRNA26924002
D009020MorphineMorphine results in increased expression of APOB protein18980684
C003297nandrolone decanoatenandrolone decanoate results in increased expression of APOB protein16153628
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of APOB mRNA"25554681
D0150581-Naphthylisothiocyanate[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of APOB mRNA27344345
D009525Niacin[Niacin co-treated with Lovastatin] results in decreased expression of APOB protein12633795
D009525Niacin[Niacin co-treated with Simvastatin] results in decreased expression of APOB protein18471454
D009525NiacinNiacin results in decreased expression of APOB protein11701466|1553996
D009532NickelAPOB protein binds to Nickel23896426
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of APOB protein"19637192
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of APOB protein]"19637192
C025256nonylphenolnonylphenol results in increased expression of APOB mRNA17010207
D016912Levonorgestrel[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of APOB protein15769986
C464660obeticholic acidobeticholic acid results in increased expression of APOB mRNA27939613
C025589ochratoxin Aochratoxin A results in decreased expression of APOB mRNA16251485|1971763
D019301Oleic AcidOleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein]15618547
D019301Oleic AcidBezafibrate inhibits the reaction [Oleic Acid results in increased expression of APOB protein]12048068
D019301Oleic Acid[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein17237316
D019301Oleic AcidOleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]15618547
D019301Oleic AcidOleic Acid results in increased expression of and results in increased secretion of APOB protein19383982
D019301Oleic AcidOleic Acid results in increased expression of APOB protein12048068
D019301Oleic AcidEthanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA]26854922
D019301Oleic Acid[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA26854922
D019301Oleic AcidOleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein]15618547
C076029olanzapineolanzapine results in increased phosphorylation of APOB protein25821032
D010100OxygenOxygen deficiency results in decreased expression of APOB mRNA24205000
C005958palmidrolpalmidrol affects the folding of APOB protein16115474
D019308Palmitic AcidEthanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA]26854922
D019308Palmitic Acid[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA26854922
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of APOB mRNA23602845
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of APOB mRNA21705711
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of APOB mRNA17560707
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of APOB protein26879310
C023036perfluorooctanoic acidperfluorooctanoic acid affects the localization of APOB protein10101272
D010634PhenobarbitalPhenobarbital results in decreased expression of APOB mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of APOB mRNA"27188386
C060836pioglitazonepioglitazone results in decreased expression of APOB protein16324916
C006253pirinixic acidpirinixic acid results in decreased expression of APOB protein15537571
C006253pirinixic acidpirinixic acid results in increased secretion of APOB protein16282640
C006253pirinixic acidpirinixic acid results in increased secretion of APOB protein alternative form15537571
D028321Plant PreparationsPlant Preparations inhibits the reaction [Fructose results in increased expression of APOB protein]27531227
D059808PolyphenolsPolyphenols results in decreased expression of APOB protein16046716
D059808PolyphenolsPolyphenols results in decreased expression of APOB mRNA16293270
D011137PolystyrenesPolystyrenes analog results in decreased expression of APOB protein8461338
D011137PolystyrenesSimvastatin promotes the reaction [Polystyrenes analog results in decreased expression of APOB protein]8461338
D011192Potassium DichromatePotassium Dichromate affects the expression of APOB mRNA23608068
C009041primycinprimycin results in decreased expression of APOB mRNA28916286
D011341ProbucolProbucol results in decreased expression of APOB mRNA16292755
D011374ProgesteroneProgesterone results in increased expression of APOB mRNA19690047
C015586propiverinepropiverine binds to APOB protein29273565
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of APOB protein2725289|7442475|
D011794QuercetinAscorbic Acid promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D011794Quercetin[Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOB mRNA17639512
D011794QuercetinQuercetin inhibits the reaction [CEBPB protein results in increased expression of APOB mRNA]25875015
D011794QuercetinQuercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]17475462
D011794QuercetinQuercetin results in decreased expression of APOB mRNA21632981|2587501
D011794QuercetinQuercetin results in decreased expression of APOB protein25875015
D011794QuercetinQuercetin results in decreased secretion of APOB protein12612140
D011794QuercetinVitamin E promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D011794QuercetinQuercetin results in increased expression of APOB mRNA21565894
C059514resveratrolresveratrol results in decreased secretion of APOB protein12612140
C059514resveratrolresveratrol inhibits the reaction [Dietary Fats results in increased expression of APOB protein]18166149
C059514resveratrolresveratrol results in decreased expression of APOB protein25505154
C089032rimonabantrimonabant results in increased secretion of APOB protein20110567
C089730rosiglitazonerosiglitazone results in increased secretion of APOB protein20503262
D000068718Rosuvastatin CalciumRosuvastatin Calcium results in decreased expression of APOB protein15539964|1870296
D012643SeleniumSelenium inhibits the reaction [Cholesterol results in increased expression of APOB protein]16581047
D012643SeleniumSelenium results in decreased expression of APOB protein16271152
D012715Sesame OilSesame Oil results in decreased expression of APOB mRNA29191790
D019821SimvastatinAPOB polymorphism affects the susceptibility to Simvastatin12901521
D019821SimvastatinHMGCR polymorphism promotes the reaction [[LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB]20413733
D019821Simvastatin[LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB20413733
D019821Simvastatin[Niacin co-treated with Simvastatin] results in decreased expression of APOB protein18471454
D019821SimvastatinSimvastatin results in decreased expression of APOB protein10498134|1263379
D019821SimvastatinSimvastatin results in decreased secretion of APOB protein11728391|1627634
D019821SimvastatinSimvastatin promotes the reaction [Polystyrenes analog results in decreased expression of APOB protein]8461338
D019821SimvastatinSimvastatin results in decreased expression of APOB mRNA8461338
D019821SimvastatinSimvastatin results in decreased expression of APOB protein8289597
D012906SmokeSmoke results in decreased expression of APOB mRNA21095227
D019346Sodium Acetate[Sodium Acetate co-treated with acetic anhydride] results in increased acetylation of APOB protein11304478
C009277sodium arsenatesodium arsenate results in decreased expression of APOB mRNA16882884
C017947sodium arsenitesodium arsenite affects the expression of APOB mRNA19590694
C016104sodium bichromatesodium bichromate affects the expression of APOB mRNA22110744
D012969Sodium FluorideSodium Fluoride results in increased expression of APOB mRNA27862939
D013629TamoxifenTamoxifen results in decreased expression of APOB mRNA19224547
C003377taxifolintaxifolin results in decreased expression of APOB protein11108730
C003377taxifolintaxifolin results in decreased secretion of APOB protein15380446
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of APOB mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [NFE2L2 gene mutant form results in decreased expression of APOB mRNA]21846477
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of APOB mRNA21846477|2823826
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of APOB mRNA22539624
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of APOB mRNA15703262
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of APOB mRNA16267337
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of APOB mRNA20959002
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of APOB mRNA11752688|1564457
D013752TetracyclineTetracycline results in decreased expression of APOB mRNA19224547
D013853ThioacetamideThioacetamide inhibits the reaction [SOD1 gene mutant form results in decreased expression of APOB protein]27349771
C423915TO-901317TO-901317 results in decreased expression of APOB protein28903485
C423915TO-901317TO-901317 results in increased expression of APOB mRNA28903485
D014241TrichloroethyleneTrichloroethylene results in decreased expression of APOB mRNA19448997
C012589trichostatin Atrichostatin A results in decreased expression of APOB mRNA15901671
D014280Triglycerides[bisphenol A results in decreased expression of APOB mRNA] which affects the abundance of Triglycerides23399309
D014280Triglycerideswortmannin inhibits the reaction [[bisphenol A results in decreased expression of APOB mRNA] which results in decreased abundance of Triglycerides]23399309
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in decreased expression of APOB mRNA17982090
C406224valdecoxibvaldecoxib results in decreased expression of APOB mRNA24136188
D014635Valproic AcidValproic Acid results in decreased expression of APOB mRNA15901671
D014635Valproic AcidValproic Acid results in decreased expression of APOB mRNA23179753|2718838
D014635Valproic AcidValproic Acid results in decreased methylation of APOB gene29154799
D014635Valproic AcidValproic Acid results in increased expression of APOB mRNA25716160
D000068756Valsartanfluvastatin promotes the reaction [[Valsartan co-treated with benazepril] results in decreased expression of APOB protein]20671225
D000068756Valsartan[Valsartan co-treated with benazepril] results in decreased expression of APOB protein20671225
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of APOB gene25560391
D025101Vitamin B 6[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein17237316
D014810Vitamin E[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein17237316
D014810Vitamin EVitamin E promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
D014810Vitamin EVitamin E promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]]17475462
C111237vorinostatvorinostat results in decreased expression of APOB mRNA27188386
C009687wortmanninwortmannin inhibits the reaction [bisphenol A results in decreased expression of APOB mRNA]23399309
C009687wortmanninwortmannin inhibits the reaction [[bisphenol A results in decreased expression of APOB mRNA] which results in decreased abundance of Triglycerides]23399309
D015032ZincAPOB protein binds to Zinc23896426
D015032Zinc"Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of APOB protein]"19637192
D015032Zinc[Ethanol co-treated with Zinc] results in increased expression of APOB mRNA19637192
D015032ZincZinc deficiency affects the expression of APOB mRNA24155903
D015032Zinc[Zinc deficiency co-treated with Ethanol] affects the expression of APOB mRNA24155903
D015032ZincZinc deficiency affects the expression of APOB mRNA modified form10498758
D015032ZincZinc deficiency results in decreased expression of APOB protein modified form10498758
D015034Zinc OxideZinc Oxide analog results in increased expression of APOB mRNA27215404

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI8245722  16203724  21911577  22580899  24447298  25108285  
26224785  27138255  
GO:0005543phospholipid binding-IDA7126555  
GO:0008201heparin binding-IDA16233946  
GO:0017127cholesterol transporter activity-IMP15797858  
GO:0035473lipase binding-IPI9685400  
GO:0050750low-density lipoprotein particle receptor binding-IMP2563166  15797858  
GO ID GO Term Qualifier Evidence PubMed
GO:0001523retinoid metabolic process-TAS-  
GO:0001701in utero embryonic development-IEA-  
GO:0002224toll-like receptor signaling pathway-TAS-  
GO:0006642triglyceride mobilization-IEA-  
GO:0006898receptor-mediated endocytosis-TAS-  
GO:0007283spermatogenesis-IEA-  
GO:0007399nervous system development-IEA-  
GO:0008203cholesterol metabolic process-IMP2563166  
GO:0009566fertilization-IEA-  
GO:0009615response to virus-IEP16548883  
GO:0009743response to carbohydrate-IEA-  
GO:0009791post-embryonic development-IEA-  
GO:0010269response to selenium ion-IEA-  
GO:0010628positive regulation of gene expression-IEA-  
GO:0010744positive regulation of macrophage derived foam cell differentiation-IDA17244792  18322245  19114110  
GO:0010884positive regulation of lipid storage-IDA18322245  
GO:0010886positive regulation of cholesterol storage-IDA19114110  
GO:0019433triglyceride catabolic process-IEA-  
GO:0030301cholesterol transport-IMP2563166  
GO:0030317flagellated sperm motility-IEA-  
GO:0032355response to estradiol-IEA-  
GO:0032496response to lipopolysaccharide-IEA-  
GO:0033344cholesterol efflux-IEA-  
GO:0034371chylomicron remodeling-TAS-  
GO:0034374low-density lipoprotein particle remodeling-IMP15797858  
GO:0034374low-density lipoprotein particle remodeling-TAS-  
GO:0034378chylomicron assembly-TAS-  
GO:0034379very-low-density lipoprotein particle assembly-IC15308631  
GO:0034379very-low-density lipoprotein particle assembly-TAS-  
GO:0034382chylomicron remnant clearance-TAS-  
GO:0034383low-density lipoprotein particle clearance-IMP2563166  15797858  
GO:0034383low-density lipoprotein particle clearance-TAS-  
GO:0034447very-low-density lipoprotein particle clearance-TAS-  
GO:0042158lipoprotein biosynthetic process-IEA-  
GO:0042159lipoprotein catabolic process-IEA-  
GO:0042632cholesterol homeostasis-IMP2563166  
GO:0042953lipoprotein transport-IEA-  
GO:0043687post-translational protein modification-TAS-  
GO:0044267cellular protein metabolic process-TAS-  
GO:0045540regulation of cholesterol biosynthetic process-IEA-  
GO:0048844artery morphogenesis-IEA-  
GO:0050900leukocyte migration-TAS-  
GO:0061024membrane organization-TAS-  
GO:0071356cellular response to tumor necrosis factor-IEA-  
GO:0071379cellular response to prostaglandin stimulus-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-HDA27068509  
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-ISS22261194  
GO:0005737cytoplasm-IDA22580899  
GO:0005769early endosome-TAS-  
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0005789endoplasmic reticulum membrane-TAS-  
GO:0005790smooth endoplasmic reticulum-TAS-  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-TAS-  
GO:0010008endosome membrane-TAS-  
GO:0030669clathrin-coated endocytic vesicle membrane-TAS-  
GO:0031904endosome lumen-TAS-  
GO:0034359mature chylomicron-IDA4363408  
GO:0034360chylomicron remnant-TAS6099394  
GO:0034361very-low-density lipoprotein particle-IDA4363408  15308631  
GO:0034362low-density lipoprotein particle-IDA4363408  
GO:0034363intermediate-density lipoprotein particle-IDA1917954  
GO:0042627chylomicron-IDA4363408  8245722  
GO:0043025neuronal cell body-IDA22897442  
GO:0043202lysosomal lumen-TAS-  
GO:0043231intracellular membrane-bounded organelle-IDA-  
GO:0070062extracellular exosome-HDA23533145  
GO:0070971endoplasmic reticulum exit site-IDA27138255  
GO:0071682endocytic vesicle lumen-TAS-  
KEGG ID KEGG Term
hsa04975Fat digestion and absorption
hsa04977Vitamin digestion and absorption
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-1430728MetabolismTAS
R-HSA-1430728MetabolismIEA
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-168898Toll-Like Receptors CascadesTAS
R-HSA-174824Plasma lipoprotein assembly, remodeling, and clearanceTAS
R-HSA-174824Plasma lipoprotein assembly, remodeling, and clearanceIEA
R-HSA-196854Metabolism of vitamins and cofactorsTAS
R-HSA-196854Metabolism of vitamins and cofactorsIEA
R-HSA-199991Membrane TraffickingTAS
R-HSA-202733Cell surface interactions at the vascular wallTAS
R-HSA-2173782Binding and Uptake of Ligands by Scavenger ReceptorsTAS
R-HSA-2173782Binding and Uptake of Ligands by Scavenger ReceptorsIEA
R-HSA-2187338Visual phototransductionTAS
R-HSA-2187338Visual phototransductionIEA
R-HSA-3000471Scavenging by Class B ReceptorsTAS
R-HSA-3000471Scavenging by Class B ReceptorsIEA
R-HSA-3000480Scavenging by Class A ReceptorsIEA
R-HSA-3000480Scavenging by Class A ReceptorsTAS
R-HSA-3000484Scavenging by Class F ReceptorsTAS
R-HSA-3000484Scavenging by Class F ReceptorsIEA
R-HSA-3000497Scavenging by Class H ReceptorsTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-372790Signaling by GPCRIEA
R-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)TAS
R-HSA-382551Transport of small moleculesTAS
R-HSA-382551Transport of small moleculesIEA
R-HSA-388396GPCR downstream signallingTAS
R-HSA-388396GPCR downstream signallingIEA
R-HSA-392499Metabolism of proteinsTAS
R-HSA-418346Platelet homeostasisTAS
R-HSA-418594G alpha (i) signalling eventsTAS
R-HSA-418594G alpha (i) signalling eventsIEA
R-HSA-432142Platelet sensitization by LDLTAS
R-HSA-5653656Vesicle-mediated transportTAS
R-HSA-5653656Vesicle-mediated transportIEA
R-HSA-5686938Regulation of TLR by endogenous ligandTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6806667Metabolism of fat-soluble vitaminsTAS
R-HSA-6806667Metabolism of fat-soluble vitaminsIEA
R-HSA-8856825Cargo recognition for clathrin-mediated endocytosisTAS
R-HSA-8856828Clathrin-mediated endocytosisTAS
R-HSA-8866423VLDL assemblyTAS
R-HSA-8957275Post-translational protein phosphorylationTAS
R-HSA-8963888Chylomicron assemblyTAS
R-HSA-8963898Plasma lipoprotein assemblyTAS
R-HSA-8963899Plasma lipoprotein remodelingTAS
R-HSA-8963901Chylomicron remodelingTAS
R-HSA-8964026Chylomicron clearanceTAS
R-HSA-8964026Chylomicron clearanceIEA
R-HSA-8964038LDL clearanceTAS
R-HSA-8964038LDL clearanceIEA
R-HSA-8964041LDL remodelingTAS
R-HSA-8964043Plasma lipoprotein clearanceTAS
R-HSA-8964043Plasma lipoprotein clearanceIEA
R-HSA-8964046VLDL clearanceIEA
R-HSA-8964046VLDL clearanceTAS
R-HSA-975634Retinoid metabolism and transportTAS
R-HSA-975634Retinoid metabolism and transportIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18261682High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies. (2008 Feb 12)van der Steeg WAJ Am Coll Cardiol
18835594Associations of alcohol consumption with blood pressure, lipoproteins, and subclinical inflammation among Turks. (2008 Nov)Onat AAlcohol
18634985Childhood levels of serum apolipoproteins B and A-I predict carotid intima-media thickness and brachial endothelial function in adulthood: the cardiovascular risk in young Finns study. (2008 Jul 22)Juonala MJ Am Coll Cardiol
24404629Familial Hypercholesterolemia (1993)Youngblom E-
28320750Metabolic Mediators of the Effects of Family History and Genetic Risk Score on Coronary Heart Disease-Findings From the Malmo Diet and Cancer Study. (2017 Mar 20)Fritz JJ Am Heart Assoc
7986307The contribution of lipids to coronary heart disease in diabetes mellitus. (1994)Stewart MWJ Intern Med Suppl
12006397Impact of alcohol intake on measures of lipid metabolism depends on context defined by gender, body mass index, cigarette smoking, and apolipoprotein E genotype. (2002 May 1)Lussier-Cacan SArterioscler Thromb Vasc Biol
28672200Impact of smoking on the observed levels of apolipoprotein B: Data from NHANES 2007-2012. (2017 Jul)Jain RBEnviron Toxicol Pharmacol
9423801Small, dense LDL particle concentration correlates with plasminogen activator inhibitor type-1 (PAI-1) activity. (1997 Dec)Vaisanen SThromb Haemost
15864114Genetic and environmental factors affecting the response to statin therapy in patients with molecularly defined familial hypercholesterolaemia. (2005 Apr)Miltiadous GPharmacogenet Genomics
28072742The nonlinear association between apolipoprotein B to apolipoprotein A1 ratio and type 2 diabetes. (2017 Jan)Mao YMedicine (Baltimore)
9878681Ionizing radiation and genetic risks. VI. Chronic multifactorial diseases: a review of epidemiological and genetical aspects of coronary heart disease, essential hypertension and diabetes mellitus. (1999 Jan)Sankaranarayanan KMutat Res
18504188[Risk factors and coronary angiographic findings in young and elderly patients with acute myocardial infarction: a comparative analysis]. (2008 May)Zhang WPNan Fang Yi Ke Da Xue Xue Bao
21129046Apolipoprotein B/A-I and total cholesterol/high-density lipoprotein cholesterol ratios both predict cardiovascular events in the general population independently of nonlipid risk factors, albuminuria and C-reactive protein. (2011 Feb)Kappelle PJJ Intern Med
23375686Spectrum of mutations and phenotypic expression in patients with autosomal dominant hypercholesterolemia identified in Italy. (2013 Apr)Bertolini SAtherosclerosis
18446714Body mass index and cardiovascular risk factors and biomarkers in hemodialysis patients. (2008 Mar-Apr)Bossola MJ Nephrol
19482846Potentially modifiable risk factors associated with myocardial infarction in China: the INTERHEART China study. (2009 Nov)Teo KKHeart
27651477Synergistic and Non-synergistic Associations for Cigarette Smoking and Non-tobacco Risk Factors for Cardiovascular Disease Incidence in the Atherosclerosis Risk In Communities (ARIC) Study. (2017 Jul 1)Lubin JHNicotine Tob Res
22167477Parental influences on cardiovascular risk factors in Swedish children aged 5-14 years. (2012 Dec)Khanolkar AREur J Public Health
7583549Differences in the phenotypic characteristics of subjects with familial defective apolipoprotein B-100 and familial hypercholesterolemia. (1995 Oct)Miserez ARArterioscler Thromb Vasc Biol
18755461Glycoxidized LDL increases lectin-like oxidized low density lipoprotein receptor-1 in diabetes mellitus. (2009 Apr)Shiu SWAtherosclerosis
24879358Insulin resistance predicts early cardiovascular morbidity in men without diabetes mellitus, with effect modification by physical activity. (2015 Jul)Hellgren MIEur J Prev Cardiol
24760540Association of HDL-C and apolipoprotein A-I with the risk of type 2 diabetes in subjects with impaired fasting glucose. (2014 Jul)Hwang YCEur J Endocrinol
20348046[Paraoxonase 1 (PON1) activity and lipid parameters in Tunisian smokers]. (2010 Mar-Apr)Haj Mouhamed DAnn Biol Clin (Paris)
19476111Retrospective analysis of risk factors in young patients with coronary artery disease in Guangdong and Zhejiang, China. (2009 Apr)Fang CActa Cardiol
11535564Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoproteins A-I and B, and HDL density subfractions: The Atherosclerosis Risk in Communities (ARIC) Study. (2001 Sep 4)Sharrett ARCirculation
11575217[APOC3, CETP, beta-fibrinogen and MTHFR are genetic determinants of carotid intim-media thickness (Stanislas cohort)]. (2001 Aug)Pallaud CArch Mal Coeur Vaiss
16677651Remnant particles are the major determinant of an increased intima media thickness in patients with familial combined hyperlipidemia (FCH). (2007 Mar)ter Avest EAtherosclerosis
7569454[Indicators of atherosclerosis risk. Evaluation with coronary angiography in non diabetic men with total cholesterol levels equal to or below 240 mg/dl]. (1995 Feb)Arteaga ARev Med Chil
22252480Relationship between blood pressure, cholesterolemia and serum apolipoprotein B in a large population sample: the Brisighella Heart Study. (2012 Mar)Cicero AFJ Hypertens
25620253[Association between apolipoprotein A1-75 bp gene polymorphisms and risk for dyslipidemia and coronary artery disease]. (2014 Nov)Wei XZhonghua Xin Xue Guan Bing Za Zhi
9247728Study of apoB gene signal peptide insertion/deletion polymorphism in a healthy Serbian population: no association with serum lipid levels. (1997 Jul 4)Glisic SClin Chim Acta
9430858Incidence and risk factors of atherosclerotic cardiovascular accidents in predialysis chronic renal failure patients: a prospective study. (1997 Dec)Jungers PNephrol Dial Transplant
10073983Lipid and apolipoprotein predictors of atherosclerosis in youth: apolipoprotein concentrations do not materially improve prediction of arterial lesions in PDAY subjects. The PDAY Research Group. (1999 Mar)Rainwater DLArterioscler Thromb Vasc Biol
10436103Carotid artery diameter correlates with risk factors for cardiovascular disease in a population of 55-year-old subjects. (1999 Aug)Jensen-Urstad KStroke
21244559Lipoprotein(a) identifies cardiovascular risk in childhood: the Australian Aboriginal Birth Cohort Study. (2011 May)Cunningham TEJ Paediatr Child Health
27169840Risk factors, topographic patterns and mechanism analysis of intracranial atherosclerotic stenosis ischemic stroke. (2017 Mar)Wang YInt J Neurosci
21176135Peroxisome proliferator-activated receptor delta +294T > C polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. (2010 Dec 21)Miao LLipids Health Dis
28666478Cardiovascular risk factors predate the onset of symptoms of rheumatoid arthritis: a nested case-control study. (2017 Jun 30)Kokkonen HArthritis Res Ther
22187965The causal exposure model of vascular disease. (2012 Apr)Sniderman ADClin Sci (Lond)
16677656Do allelic variants of the connexin37 1019 gene polymorphism differentially predict for coronary artery disease and myocardial infarction? (2007 Apr)Wong CWAtherosclerosis
21624357Associations of atherosclerotic risk factors with oxidized low-density lipoprotein evaluated by LOX-1 ligand activity in healthy men. (2011 Aug 17)Uchida KClin Chim Acta
20716347Interactions of the apolipoprotein C-III 3238C>G polymorphism and alcohol consumption on serum triglyceride levels. (2010 Aug 17)Ruixing YLipids Health Dis
17142622Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk. (2006 Dec)Humphries SEJ Med Genet
21960651Apolipoprotein B, oxidized low-density lipoprotein, and LDL particle size in predicting the incidence of metabolic syndrome: the Cardiovascular Risk in Young Finns study. (2012 Dec)Koskinen JEur J Prev Cardiol
2026222Mean levels and distribution of some risk factors for atherosclerosis in Sardinia: the ATS-Sardegna Survey. (1991 Jan)Muntoni SEur J Epidemiol
24863406Sleep duration and abnormal serum lipids: the China Health and Nutrition Survey. (2014 Jul)Zhan YSleep Med
28353356Causative mutations and premature cardiovascular disease in patients with heterozygous familial hypercholesterolaemia. (2017 Jul)Rubba PEur J Prev Cardiol
20019460[Major influence of dysfunctions of protective serum proteins on cardiometabolic risk among Turks and gender difference]. (2009 Sep)Onat ATurk Kardiyol Dern Ars
25932792Effects of niacin and omega-3 fatty acids on the apolipoproteins in overweight patients with elevated triglycerides and reduced HDL cholesterol. (2015 Jun)Savinova OVAtherosclerosis
24930071Unexpected inverse relationship between impaired glucose metabolism and lipoprotein-associated phospholipase A2 activity in patients with stable vascular disease. (2014 Jul)Mayer O JrEur J Intern Med
22752805Prevalence of myocardial infarction polymorphisms in Afyonkarahisar, Western Turkey. (2012 Sep)Onrat STMol Biol Rep
10803663Plasma lipoprotein(a) distribution and its correlates among Samoans. (2000 Apr)Kamboh MIHum Biol
28168401Dyslipidemia in systemic lupus erythematosus. (2017 Apr)Szabo MZImmunol Res
11359462APOC3, CETP, fibrinogen, and MTHFR are genetic determinants of carotid intima-media thickness in healthy men (the Stanislas cohort). (2001 May)Pallaud CClin Genet
16372134Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-beta 1-42 and plasma apolipoprotein levels. (2006)Katzov HJ Hum Genet
22951857Dysfunction of high-density lipoprotein and its apolipoproteins: new mechanisms underlying cardiometabolic risk in the population at large. (2012 Jun)Onat ATurk Kardiyol Dern Ars
18676970Concentration of apolipoprotein B is comparable with the apolipoprotein B/apolipoprotein A-I ratio and better than routine clinical lipid measurements in predicting coronary heart disease mortality: findings from a multi-ethnic US population. (2009 Mar)Sierra-Johnson JEur Heart J
21479456Modification of the effect of smoking on cholesterol in Japanese carriers of a PTPN11 polymorphism. (2008 Jul-Aug)Okada RMol Med Rep
20566576Moderate physical activity is associated with lower ApoB/ApoA-I ratios independently of other risk factors in healthy, middle-aged men. (2010 Nov)Behre CAngiology
9672070Apolipoprotein B and coronary artery disease in women: a cross-sectional study in women undergoing their first coronary angiography. (1998 Jul)Westerveld HTArterioscler Thromb Vasc Biol
10780336Lipoprotein profiles, not anthropometric measures, correlate with serum lipoprotein(a) values in children: the Taipei children heart study. (2000 Jan)Chu NFEur J Epidemiol
21743088Longitudinal levels of apolipoproteins and antibodies against phosphorylcholine are independently associated with carotid artery atherosclerosis 5 years after rheumatoid arthritis onset--a prospective cohort study. (2011 Oct)Ajeganova SRheumatology (Oxford)
18774540ApoB/ApoA-I ratio in young patients with ischemic cerebral stroke or peripheral arterial disease. (2008 Sep)Sabino APTransl Res
24794068Normal thyroid-stimulating hormone levels, autoimmune activation, and coronary heart disease risk. (2015 Feb)Onat AEndocrine
11874431Insulin, insulin propeptides and intima-media thickness in the carotid artery in 58-year-old clinically healthy men. The Atherosclerosis and Insulin Resistance study (AIR). (2002 Feb)Bokemark LDiabet Med
7981840Concentrations of Lp(a) in black and white young adults: relations to risk factors for cardiovascular disease. (1994 Sep)Howard BVAnn Epidemiol
20538481Apolipoprotein B-to-A1 ratio as a predictor of acute ischemic nonembolic stroke in elderly subjects. (2010 Nov-Dec)Kostapanos MSJ Stroke Cerebrovasc Dis
18468260Distribution of apoB/apoA-1 ratio and blood lipids in Sami, Kven and Norwegian populations: the SAMINOR study. (2008 Feb)Nystod TInt J Circumpolar Health
26892134Serum level of LOX-1 ligand containing ApoB is associated with increased carotid intima-media thickness in Japanese community-dwelling men, especially those with hypercholesterolemia LOX-1 ligand and IMT in Japanese. (2016 Jan-Feb)Okamura TJ Clin Lipidol
27236033LDLR, ApoB and ApoE genes polymorphisms and classical risk factors in premature coronary artery disease. (2016 Sep 30)Abd El-Aziz TAGene
20414796Elevated depressive symptoms and compositional changes in LDL particles in middle-aged men. (2010 Jun)Lehto SMEur J Epidemiol
17137217Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension. (2006 Aug)Kokubo YHypertens Res
29748187Complete and Partial LCAT Deficiency are Differentially Associated with Atherosclerosis. (2018 May 10)Oldoni FCirculation
24558984Influence of vanadium on serum lipid and lipoprotein profiles: a population-based study among vanadium exposed workers. (2014 Feb 24)Zhang YLipids Health Dis
18484661Relationship between smoking and dyslipidemia in western Chinese elderly males. (2008)Tan XJJ Clin Lab Anal
8946271Relationship of lipoproteins, apolipoproteins, triglycerides and lipid ratios to plasma total cholesterol in young adults: the CARDIA Study. Coronary Artery Risk Development in Young Adults. (1996 Aug)Iribarren CJ Cardiovasc Risk
2128269[Serum apolipoprotein AI, B levels in patients with coronary diseases]. (1990 Aug)He YZhonghua Xin Xue Guan Bing Za Zhi
28739396Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population. (2017 Sep 10)Mastana SGene
27349005Association Between Cardiovascular Risk Factors and Serum Thyrotropin Concentration Among Healthy Chinese Subjects and Subjects with Unsuspected Subclinical Hypothyroidism. (2016)Wu JClin Lab
24407534Apolipoproteins AI/B/E gene polymorphism and their plasma levels in patients with coronary artery disease in a tertiary care-center of Eastern India. (2013 Dec)Biswas SIndian Heart J
23731637Cardiovascular risk profile in patients with spondyloarthritis. (2014 Jan)Papagoras CJoint Bone Spine
22893714Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication. (2012 Nov)Benn MJ Clin Endocrinol Metab
28506386Serum triglyceride, high-density lipoprotein cholesterol, apolipoprotein B, and coronary heart disease in a Chinese population undergoing coronary angiography. (2017 May - Jun)Ling YJ Clin Lipidol
15345795Apolipoprotein B/apolipoprotein A-I in relation to the metabolic syndrome and change in carotid artery intima-media thickness during 3 years in middle-aged men. (2004 Oct)Wallenfeldt KStroke
16809576Potential new risk factors for ischemic stroke: what is their potential? (2006 Aug)Hankey GJStroke
25428744Correlation of lipid parameters and markers of insulin resistance: does smoking make a difference? (2014)Cibickova LPhysiol Res
23028747Prediction of risk factors for coronary heart disease using Framingham Risk Score in Korean men. (2012)Ryoo JHPLoS One
20395681High absolute coronary disease risk among Turks: involvement of risk factors additional to conventional ones. (2010)Onat ACardiology
23125402Association of risk factors with acute myocardial infarction in Middle Eastern countries: the INTERHEART Middle East study. (2014 Apr)Gehani AAEur J Prev Cardiol
21692678Cardiovascular disease risk factors in homeless people. (2011 Aug)Kaldmae MUps J Med Sci
14578319Fractional esterification rate of cholesterol and ratio of triglycerides to HDL-cholesterol are powerful predictors of positive findings on coronary angiography. (2003 Nov)Frohlich JClin Chem
26424733Elevated low-density lipoprotein cholesterol is independently associated with obstructive sleep apnea: evidence from a large-scale cross-sectional study. (2016 May)Xu HSleep Breath
25682025Low levels of IgG autoantibodies against the apolipoprotein B antigen p210 increases the risk of cardiovascular death after carotid endarterectomy. (2015 Apr)Asciutto GAtherosclerosis
19520708The joint effects of apolipoprotein B, apolipoprotein A1, LDL cholesterol, and HDL cholesterol on risk: 3510 cases of acute myocardial infarction and 9805 controls. (2009 Sep)Parish SEur Heart J
8218104Parental history of early myocardial infarction is associated with decreased levels of lipoparticle AI in adolescents. (1993 Nov)Amouyel PArterioscler Thromb
21958700Establishment of chemiluminescence enzyme immunoassay for apolipoprotein B-48 and its clinical applications for evaluation of impaired chylomicron remnant metabolism. (2012 Jan 18)Hanada HClin Chim Acta
23541965Oxidation-specific biomarkers and risk of peripheral artery disease. (2013 May 28)Bertoia MLJ Am Coll Cardiol
9481602Relationship between anthropometric variables and lipid levels among school children: The Taipei Children Heart Study. (1998 Jan)Chu NFInt J Obes Relat Metab Disord
23040261C-reactive protein distribution and correlation with traditional cardiovascular risk factors in the Italian population. (2013 Mar)Casula MEur J Intern Med
24813034Paraoxonase 1 activity and lipid profile in schizophrenic patients. (2014 Jun)Mabrouk HAsian J Psychiatr
11330505Intact insulin, insulin propeptides, and intima-media thickness in the femoral artery in 58-year-old clinical healthy men--the Atherosclerosis and Insulin Resistance Study. (2001 Apr)Bokemark LAngiology
15364185Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. (2004 Sep 11-17)Yusuf SLancet
11378831Apolipoprotein B, ratio of total cholesterol to HDL-C, and blood pressure in abdominally obese white and black American women. (2001 May)Okosun ISJ Hum Hypertens
20972250Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population. (2011 Jan)Park MHJ Med Genet
14761628[Study on the relationship between smoking, alcohol intake and hyperlipidemia in fishermen]. (2003 Dec)Wang JYZhonghua Liu Xing Bing Xue Za Zhi
11714857Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. (2001 Nov)Pallaud CJ Lipid Res
28101967Host-related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans. (2017 Jun)Bohn TMol Nutr Food Res
27816355Correlations Between Serum Apolipoprotein A-I and Formation of Vocal Cord Polyp. (2017 May)Zhang HPJ Voice
8854709A comparison of cardiovascular risk as measured by compound blood lipid indices and two indices including lifestyle factors in occupational health service. (1996 Aug)Berg JEOccup Med (Lond)
11433198Does alpha-1-proteinase inhibitor play a protective role in coronary atherosclerosis? (2001 Jul-Aug)Stakisaitis DMed Sci Monit
25672030Novel atherosclerotic risk factors and angiographic profile of young Gujarati patients with acute coronary syndrome. (2014 Jul)Prajapati JJ Assoc Physicians India
22646906Association of rs2072183 SNP and serum lipid levels in the Mulao and Han populations. (2012 May 30)Miao LLipids Health Dis
22848405Comparison of apolipoprotein (apoB/apoA-I) and lipoprotein (total cholesterol/HDL) ratio determinants. Focus on obesity, diet and alcohol intake. (2012)Tognon GPLoS One
7695175Detection and treatment of elevated blood lipids and other risk factors for coronary artery disease in youth. (1995 Jan 17)Kwiterovich PO JrAnn N Y Acad Sci
22407430Consistency between cross-sectional and longitudinal SNP: blood lipid associations. (2012 Feb)Costanza MCEur J Epidemiol
23883544Renal insufficiency without albuminuria is associated with peripheral artery atherosclerosis and lipid metabolism disorders in patients with type 2 diabetes. (2013)Yamashita TJ Atheroscler Thromb
26759540The association between smoking and the prevalence of metabolic syndrome and its components in patients with psoriasis aged 30 to 49 years. (2015 Oct)Owczarczyk-Saczonek ABPostepy Dermatol Alergol
26680672Hypertriglyceridemic waist - a simple clinical tool to detect cardiometabolic risk: comparison with harmonized definition of metabolic syndrome. (2015)Vaverkova HPhysiol Res
19234732The carotid artery plaque size and echogenicity are related to different cardiovascular risk factors in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. (2009 May)Andersson JLipids
15656025Apolipoproteins: correlation with carotid intimamedia thickness and coronary artery disease. (2004 May)Jadhav UMJ Assoc Physicians India
2060091Relation of arteriographically defined coronary artery disease to serum lipoprotein particles mapped with monoclonal antibodies. (1991 Jul)Fievet CCirculation
22465995Deterioration of endothelial function and carotid intima-media thickness in Tibetan male adolescents exposed to second-hand smoke. (2012 Dec)Yang BJ Renin Angiotensin Aldosterone Syst
25346256Associations between the Serum 25(OH)D Concentration and Lipid Profiles in Japanese Men. (2015)Sun XJ Atheroscler Thromb
1476559Serum trypsin-like activity in chronic alcoholized men: possible relationship with lipids, apoA-1 and apoB lipoproteins. (1992 Sep)Joly JPAlcohol Alcohol
21821825Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study. (2011 Oct)Ravandi AJ Lipid Res
8349099Inheritance of plasma apolipoprotein B levels in families of patients undergoing coronary arteriography at an early age. (1993)Coresh JGenet Epidemiol
16949489Is plasma oxidized low-density lipoprotein, measured with the widely used antibody 4E6, an independent predictor of coronary heart disease among U.S. men and women? (2006 Sep 5)Wu TJ Am Coll Cardiol
20362293High levels of soluble intercellular adhesion molecule-1, insulin resistance and saturated fatty acids are associated with endothelial dysfunction in healthy adolescents. (2010 Aug)Chen YAtherosclerosis
21919778Correlation between common genetic variants and risk factors associated with prediction of cardiovascular diseases in dyslipidemic patients. (2012 Mar)Kotaska KGenet Test Mol Biomarkers
9409302Familial hypercholesterolemia in the Finnish north Karelia. A molecular, clinical, and genealogical study. (1997 Nov)Vuorio AFArterioscler Thromb Vasc Biol
10655966Blood cholesterol and apolipoprotein B levels in relation to intakes of animal and plant proteins in US adults. (1999 Sep)Smit EBr J Nutr
7500552[Restenosis after percutaneous transluminal coronary angioplasty in the elderly--risk factor analysis]. (1995 Jul)Ishikawa YNihon Ronen Igakkai Zasshi
29362515Increased Risk of the APOB rs11279109 Polymorphism for CHD among the Kuwaiti Population. (2017)Al-Bustan SADis Markers
27310947Prediction of future development of cardiovascular disease with an equation to estimate apolipoprotein B: A community-based cohort study. (2016 Jun)Hwang YCMedicine (Baltimore)
18769801[Individual and population risk in acute myocardial infarction: the Chilean INTERHEART study]. (2008 May)Lanas FRev Med Chil
11580913Reference intervals for serum apolipoproteins A-I, A-II, B, C-II, C-III, and E in healthy Japanese determined with a commercial immunoturbidimetric assay and effects of sex, age, smoking, drinking, and Lp(a) level. (2001 Oct)Sakurabayashi IClin Chim Acta
18096825Femoral atherosclerosis in heterozygous familial hypercholesterolemia: influence of the genetic defect. (2008 Mar)Junyent MArterioscler Thromb Vasc Biol
9351377Postprandial elevation of ApoB-48-containing triglyceride-rich particles and retinyl esters in normolipemic males who smoke. (1997 Oct)Mero NArterioscler Thromb Vasc Biol
11887026Circulating oxidized LDL is associated with increased levels of cell-adhesion molecules in clinically healthy 58-year old men (AIR study). (2002 Mar)Hulthe JMed Sci Monit
16156880Antiretroviral therapy in HIV-positive men is associated with increased apolipoprotein CIII in triglyceride-rich lipoproteins. (2005 Sep)Rimland DHIV Med
19648057A comparison of risk factors for coronary heart disease and ischaemic stroke: the Dubbo study of Australian elderly. (2009 Oct)Simons LAHeart Lung Circ
23645505Hazardous alcohol consumption is associated with increased levels of B-type natriuretic peptide: evidence from two population-based studies. (2013 May)Leon DAEur J Epidemiol
19642911Body mass and atherogenic dyslipidemia as major determinants of blood levels of B-type natriuretic peptides in Arab subjects with acute coronary syndromes. (2009 Dec)Akanji AOMetab Syndr Relat Disord
23107276Association of MYLIP rs3757354 SNP and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations. (2012 Oct 29)Yan TTLipids Health Dis
16316964Non-high-density lipoprotein cholesterol and apolipoprotein B in the prediction of coronary heart disease in men. (2005 Nov 29)Pischon TCirculation
22111029Premature coronary artery disease and familial hypercholesterolemia: need for early diagnosis and cascade screening in the Indian population. (2012)Setia NCardiol Res Pract
20964824Lower paraoxonase 1 activity in Tunisian bipolar I patients. (2010 Oct 21)Ezzaher AAnn Gen Psychiatry
16805392[Changes in the lipoprotein metabolism in alcoholism do not recover during of prolonged remission]. (2006 Mar-Apr)Bozhko GKhBiomed Khim
9845858The importance of serum lipoprotein (a) as an independent risk factor for premature coronary artery disease in middle-aged black and white women from the United States. (1998 Nov)Dahlen GHJ Intern Med
26025389Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study. (2015 Jul)Saleheen DLancet Diabetes Endocrinol
16526201[AIP--atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice]. (2006 Jan)Dobiasova MVnitr Lek
15646744[Interheart: nine risk factors predict nine out of ten myocardial infarctions]. (2004 Nov)Scheen AJRev Med Liege
28774484Cardiovascular disease risk associated with serum apolipoprotein B is modified by serum vitamin A. (2017 Oct)Olsen TAtherosclerosis
8607042Psychological factors in the relationship between alcohol and cardiovascular morbidity. (1995 Dec)Roberts RSoc Sci Med
9157945Segregation analysis of plasma apolipoprotein B levels in familial combined hyperlipidemia. (1997 May)Bredie SJArterioscler Thromb Vasc Biol
22659528Associations between small dense LDL, HDL subfractions (HDL2, HDL3) and risk of atherosclerosis in Japanese-Americans. (2012)Maeda SJ Atheroscler Thromb
24895480Intercorrelations of lipoprotein subfractions and their covariation with lifestyle factors in healthy men. (2014 May)Parlesak AJ Clin Biochem Nutr
1947727Apolipoprotein E phenotypes, serum lipoproteins and apolipoproteins in angiographically assessed coronary heart disease. (1991 Sep)Stuyt PMScand J Clin Lab Invest
9241743Positive association of the beta fibrinogen H1/H2 gene variation to basal fibrinogen levels and to the increase in fibrinogen concentration during acute phase reaction but not to coronary artery disease and myocardial infarction. (1997 Jun)Gardemann AThromb Haemost
8399079Plasma lipoprotein and apolipoprotein levels in Taipei and Framingham. (1993 Oct)Lyu LCArterioscler Thromb
11730086Relationship of early carotid artery disease with lipoprotein (a), apolipoprotein B, and fibrinogen in asymptomatic essential hypertensive patients and normotensive subjects. (2001 Nov)Rossl AJ Investig Med
8785232Lipid parameters including lipoprotein (a) in patients undergoing CAPD and hemodialysis. (1995 Oct-Dec)Siamopoulos KCPerit Dial Int
21660913The multiplicative interactions of leukocyte counts with some other risk factors enhance the prognostic value for coronary artery disease. (2011)Rasouli MCardiol J
15479125Gender differences in plasma levels of lipoprotein (a) in patients with angiographically proven coronary artery disease. (2004)Frohlich JPhysiol Res
29272977Association between serum levels of testosterone and biomarkers of subclinical atherosclerosis. (2017 Dec 22)Rezanezhad BAging Male
11996964Assessment of atherosclerosis using carotid ultrasonography in a cohort of HIV-positive patients treated with protease inhibitors. (2002 Jun)Seminari EAtherosclerosis
22760866Elevated ApoB serum levels strongly predict early cardiovascular events. (2012 Aug)Gigante BHeart
24175066Normal levels of inflammatory markers in treated patients with familial hypercholesterolaemia: a cross-sectional study. (2012)Seed MJRSM Cardiovasc Dis
20517165Apolipoprotein C-III gene polymorphism and several environmental factors with serum lipid levels in the Guangxi Hei Yi Zhuang and Han populations. (2010 Aug)Yiyang LJ Investig Med
10396544Are risk factors for atherothrombotic disease associated with back pain sickness absence? The Whitehall II Study. (1999 Apr)Hemingway HJ Epidemiol Community Health
8724114Prevalence of hyperapobetalipoproteinemia and factors affecting the phenotype expression in children and young adults. The Cardiovascular Risk in Young Finns Study. (1996 Apr 26)Nuotio IOAtherosclerosis
18277343ApoB/ApoA1 ratio and subclinical atherosclerosis. (2008 Feb)Panayiotou AInt Angiol
20977771Association of methylenetetrahydrofolate reductase C677T polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. (2010 Oct 27)Zhang LLipids Health Dis
16272676Biochemical measures in the diagnosis of alcohol dependence using discriminant analysis. (2005 Oct)Vaswani MIndian J Med Sci
21078622Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study. (2011 Apr)Kivimaki MInt J Epidemiol
18036065Dyslipidemia and other cardiovascular risk factors in a Canadian First Nation pediatric population with type 2 diabetes mellitus. (2007 Dec)Sellers EAPediatr Diabetes
16205021Lipid, lipoprotein, apolipoprotein and lipoprotein(a) levels: reference intervals in a healthy Indian population. (2005)Ashavaid TFJ Atheroscler Thromb
20222961Association of LIPC -250G>A polymorphism and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations. (2010 Mar 11)Meng LLipids Health Dis
23555769Elevated PLA2G7 gene promoter methylation as a gender-specific marker of aging increases the risk of coronary heart disease in females. (2013)Jiang DPLoS One
28167353Genetic risk analysis of coronary artery disease in Pakistani subjects using a genetic risk score of 21 variants. (2017 Mar)Shahid SUAtherosclerosis
24051266Clusters of AMI risk factors and their association with left ventricular hypertrophy: a population-based study within the Skaraborg Project, Sweden. (2013 Oct 15)Larsson CAInt J Cardiol
23994331Serum amyloid A is independently related to apolipoprotein A-I but not to HDL-cholesterol in patients with angina pectoris. (2013 Nov)Korita IClin Biochem
16075646[Factors facilitating development of degenerative aortic valvular stenosis]. (2005)Andropova OVKlin Med (Mosk)
24228807Associations between smoking, components of metabolic syndrome and lipoprotein particle size. (2013 Sep 3)Slagter SNBMC Med
22048271Plasma oxidized low-density lipoprotein is an independent risk factor in young patients with coronary artery disease. (2011)Huang YDis Markers
1561971Comparison of the plasma levels of apolipoproteins B and A-1, and other risk factors in men and women with premature coronary artery disease. (1992 Apr 15)Kwiterovich PO JrAm J Cardiol
23096082Minor allele of the APOA4 gene T347S polymorphism predisposes to obesity in postmenopausal Turkish women. (2012 Dec)Guclu-Geyik FMol Biol Rep
21394030Association of the serum apolipoprotein levels with the occurrence of coronary vasospasm. (2011 May)Tani SCoron Artery Dis
8364758[Justification and imperatives of the campaign against excess cholesterol and prevention of atherosclerosis]. (1993 Apr)de Gennes JLBull Acad Natl Med
18476573[Study on the relationship between passive smoking and blood lipids, fibrinogen and viscosity among women who never smoke]. (2007 Dec)He YZhonghua Liu Xing Bing Xue Za Zhi
22814200Exposure to tobacco smoke in utero and subsequent plasma lipids, ApoB, and CRP among adult women in the MoBa cohort. (2012 Nov)Cupul-Uicab LAEnviron Health Perspect
29032752Association between Apolipoproteins AI and B and Ultrasound Indicators of Carotid Atherosclerosis. (2018)Zivanovic ZCurr Vasc Pharmacol
26730363Predictors of Plaque Progression in Hypertensive Angina Patients with Achieved Low-Density Lipoprotein Cholesterol Less Than 70 mg/dL after Rosuvastatin Treatment. (2015 Dec)Hong YJChonnam Med J
12820936[Lipoprotein (a) and cerebral infarction in young adults]. (2003 May)Cao GFZhonghua Liu Xing Bing Xue Za Zhi
24094290Serum creatinine is associated with coronary disease risk even in the absence of metabolic disorders. (2013 Oct)Onat AScand J Clin Lab Invest
11860787[The relationship between angiotensin converting enzyme gene polymorphism and risk factors for coronary heart disease]. (2000 Jun)Shan JZhonghua Liu Xing Bing Xue Za Zhi
10024187Serum triglyceride: a possible risk factor for ruptured abdominal aortic aneurysm. (1998 Dec)Watt HCInt J Epidemiol
19124125High apoB/apoA-I ratio is associated with increased progression rate of carotid artery intima-media thickness in clinically healthy 58-year-old men: experiences from very long-term follow-up in the AIR study. (2009 Jul)Schmidt CAtherosclerosis
18590467Association of the insertion/deletion gene polymorphism of the apolipoprotein B signal peptide with myocardial infarction in Tunisian patients. (2008)Kallel AClin Chem Lab Med
11730822Association of the A/T54 polymorphism in the intestinal fatty acid binding protein with variations in plasma lipids in the Framingham Offspring Study. (2001 Dec)Galluzzi JRAtherosclerosis
25463747LOX-1 in atherosclerotic disease. (2015 Feb 2)Sawamura TClin Chim Acta
14985310Diabetic retinopathy and serum lipoprotein subclasses in the DCCT/EDIC cohort. (2004 Mar)Lyons TJInvest Ophthalmol Vis Sci
23414319Combined influence of gene-specific cord blood methylation and maternal smoking habit on birth weight. (2013 Feb)Haworth KEEpigenomics
2683043Shift work and coronary heart disease. (1989)Knutsson AScand J Soc Med Suppl
17629106[Coronary heart disease risk factors in Croatia and worldwide: results of the Interheart study]. (2007 Jun)Carevic VActa Med Croatica
16306426The apolipoprotein B/AI ratio and the metabolic syndrome independently predict risk for myocardial infarction in middle-aged men. (2006 Feb)Lind LArterioscler Thromb Vasc Biol
23103135Interpretation of lipoprotein-associated phospholipase A2 levels is influenced by cardiac disease, comorbidities, extension of atherosclerosis and treatments. (2013 Sep 20)Charniot JCInt J Cardiol
24385235High prevalence of cardiovascular risk factors in patients with moderate or severe psoriasis in northern China. (2014 Apr)Ma LArch Dermatol Res
17587723Sex difference in the distribution of atherosclerotic risk factors and their association with peripheral arterial disease in Taiwanese type 2 diabetic patients. (2007 Jul)Tseng CHCirc J
24772377Apolipoprotein Gene Polymorphisms (APOB, APOC111, APOE) in the Development of Coronary Heart Disease in Ethnic Groups of Kazakhstan. (2014 Jan 24)Berkinbayev SJ Genet Syndr Gene Ther
23055759The association between obesity, cardiometabolic disease biomarkers, and innate immunity-related inflammation in Canadian adults. (2012)Da Costa LADiabetes Metab Syndr Obes
18333357Apolipoproteins A-I and B-markers in coronary risk evaluation. (2007)Agoston-Coldea LRom J Intern Med