Gene: DUPD1

338599
DUSP27|FMDSP
dual specificity phosphatase and pro isomerase domain containing 1
protein-coding
10q22.2
Ensembl:ENSG00000188716 Vega:OTTHUMG00000018512 UniprotKB:Q68J44
NC_000010.11
PubMed
0   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.755e-1 (AD)  9.495e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR51E10.594
GPR200.55
SSUH20.549
CDC20B0.547
SLC22A80.542
C1QTNF70.539
OR51E20.537
ALX40.525
SLC6A200.514
OSR10.513

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GPR35-0.284
CPSF4L-0.273
GAGE10-0.267
CLEC18B-0.263
IGFALS-0.258
NRN1L-0.256
NPIPB6-0.255
KIF19-0.254
TUBB8-0.252
CHI3L1-0.249

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of DUPD1 gene27153756
C006780bisphenol Abisphenol A results in decreased expression of DUPD1 mRNA25181051
D003300Copper[Copper co-treated with Dietary Sucrose] results in increased expression of DUPD1 mRNA26033743
D003300CopperCopper deficiency results in increased expression of DUPD1 mRNA26033743
D019422Dietary Sucrose[Copper co-treated with Dietary Sucrose] results in increased expression of DUPD1 mRNA26033743
D019422Dietary SucroseDietary Sucrose results in increased expression of DUPD1 mRNA26033743
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of DUPD1 mRNA"22485181
D000431EthanolEthanol results in increased expression of DUPD1 protein20621659

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004725protein tyrosine phosphatase activity-IEA-  
GO:0008138protein tyrosine/serine/threonine phosphatase activity-IDA17498703  
GO:0042803protein homodimerization activity-IDA21543850  
GO ID GO Term Qualifier Evidence PubMed
GO:0006470protein dephosphorylation-IDA17498703  
GO:0035335peptidyl-tyrosine dephosphorylation-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IEA-  
GO:0032991protein-containing complex-IDA21543850  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal