Gene: SLCO1B7

338821
LST-3|LST-3TM12|LST3|SLC21A21
solute carrier organic anion transporter family member 1B7 (putative)
protein-coding
12p12.2
Ensembl:ENSG00000205754 Vega:OTTHUMG00000169045 UniprotKB:G3V0H7
NC_000012.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.932e-1 (AD)  2.993e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7980084chr12:21069946 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CD1B0.616
NPHS20.609
RNASE110.608
OR4K30.589
TAS2R300.586
OR2M70.579
TAS2R410.577
MTRNR2L50.571
POU5F20.567
TMEM2470.566

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CCL27-0.277
CLDND2-0.25
RAB41-0.247
VPREB3-0.24
NOX1-0.232
TUBB8-0.212
SOX15-0.205
HSPB2-0.202
CNGA4-0.202
FBXL22-0.2

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of SLCO1B7 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of SLCO1B7 mRNA27392435
D004726Endosulfan[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SLCO1B7 mRNA26159488
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of SLCO1B7 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of SLCO1B7 mRNA27392435
D013749Tetrachlorodibenzodioxin[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SLCO1B7 mRNA26159488

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0015125bile acid transmembrane transporter activity-IBA21873635  
GO:0015347sodium-independent organic anion transmembrane transporter activity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0015721bile acid and bile salt transport-IBA21873635  
GO:0015721bile acid and bile salt transport-IEA-  
GO:0043252sodium-independent organic anion transport-IBA21873635  
GO:0055085transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005887integral component of plasma membrane-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal