Gene: KY

339855
MFM7
kyphoscoliosis peptidase
protein-coding
3q22.2
Ensembl:ENSG00000174611 MIM:605739 Vega:OTTHUMG00000159788 UniprotKB:Q8NBH2
NG_054713.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.841e-1 (AD)  4.485e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PXMP40.828
MTUS20.826
TUBGCP40.825
SARM10.812
INCENP0.811
CACNG20.81
KCNH10.809
SCN8A0.808
PCDHAC20.808
EFR3B0.808

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RAB13-0.494
HEY2-0.468
TGFB3-0.463
ROM1-0.461
SGMS2-0.445
GNG8-0.443
EIF4EBP1-0.44
BCL7C-0.44
CSAG1-0.428
SFN-0.426

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of KY mRNA26690555
D020106AcrylamideAcrylamide affects the expression of KY mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of KY gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of KY mRNA24449571
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of KY mRNA27195522
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehyde[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KY mRNA25566086
D004958EstradiolEstradiol results in decreased expression of KY mRNA19484750
C006780bisphenol Abisphenol A results in decreased expression of KY mRNA25181051
D003042CocaineCocaine results in decreased expression of KY mRNA17898221
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of KY mRNA21266533
C069837fullerene C60fullerene C60 results in decreased expression of KY mRNA19167457
D007545IsoproterenolIsoproterenol results in decreased expression of KY mRNA20003209
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of KY mRNA24796395
C029310lardlard results in decreased expression of KY mRNA26115784
C008261lead acetatelead acetate results in increased expression of KY mRNA20542052
D009532NickelNickel results in decreased expression of KY mRNA24768652
C028007nickel monoxidenickel monoxide results in decreased expression of KY mRNA19167457
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KY mRNA27935865
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KY mRNA27935865
D011441PropylthiouracilPropylthiouracil results in decreased expression of KY mRNA24780913
D013096SpermineSpermine results in increased expression of KY mRNA18673383
D013739TestosteroneTestosterone results in decreased expression of KY mRNA20403060
C025643vinclozolinvinclozolin results in increased expression of KY mRNA23869203

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0008233peptidase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006508proteolysis-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005856cytoskeleton-IEA-  
GO:0030018Z disc-ISS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25601500Deterministic effects after fenestrated endovascular aortic aneurysm repair. (2015 Apr)Kirkwood MLJ Vasc Surg