Gene: IDH1

3417
HEL-216|HEL-S-26|IDCD|IDH|IDP|IDPC|PICD
isocitrate dehydrogenase (NADP(+)) 1, cytosolic
protein-coding
2q34
Ensembl:ENSG00000138413 MIM:147700 Vega:OTTHUMG00000132943 UniprotKB:O75874
NG_023319.2
PubMed
0   ANCO-SNPs
ND
4   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.369e-1 (AD)  1.233e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GNAI30.857
TMX10.832
TAB20.83
CCNG10.823
MOB1A0.823
SH3GLB10.814
NFE2L20.814
SERP10.812
MCMBP0.812
RIT10.811

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.548
OR4F29-0.497
SLC7A4-0.249
DRD5-0.244
HTR6-0.238
CYP4A11-0.234
ADRA1D-0.222
ADTRP-0.221
C8orf86-0.22
ABCC12-0.22

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01727Isocitric AcidSmall Molecule320-77-4ExperimentalTarget
DB034612'-Monophosphoadenosine 5'-DiphosphoriboseSmall MoleculeExperimentalTarget
DB09374Indocyanine greenSmall Molecule3599-32-4Approved|InvestigationalEnzyme
ID Drug Name Action PubMed
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased expression of IDH1 protein"26035713
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of IDH1 mRNA"28903501
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in decreased expression of IDH1 mRNA28329830
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane affects the expression of IDH1 mRNA"18648102
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of IDH1 mRNA19191707
D000082AcetaminophenAcetaminophen results in decreased expression of IDH1 mRNA21420995|2223033
D000082AcetaminophenAcetaminophen affects the expression of IDH1 mRNA17562736
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of IDH1 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IDH1 mRNA]17585979
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of IDH1 mRNA22100608|2715375
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of IDH1 mRNA19770486
C581156AGI-5198AGI-5198 inhibits the reaction [IDH1 protein mutant form results in increased abundance of alpha-hydroxyglutarate]25895133
C581156AGI-5198AGI-5198 results in decreased activity of IDH1 protein25391653
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of IDH1 mRNA"23195993
C019417alpha-hydroxyglutarateIDH1 gene mutant form affects the abundance of alpha-hydroxyglutarate22057236
C019417alpha-hydroxyglutarateAGI-5198 inhibits the reaction [IDH1 protein mutant form results in increased abundance of alpha-hydroxyglutarate]25895133
C019417alpha-hydroxyglutarateIDH1 protein mutant form results in increased abundance of alpha-hydroxyglutarate25895133
C019417alpha-hydroxyglutarateIDH1 protein mutant form results in increased abundance of alpha-hydroxyglutarate analog25391653
C029743alpha-ketoglutaric acidIDH1 protein mutant form results in increased reduction of alpha-ketoglutaric acid25391653
C029743alpha-ketoglutaric acidIDH1 protein results in increased carboxylation of alpha-ketoglutaric acid23504317
D000535AluminumAluminum results in decreased activity of IDH1 protein15486972
D000643Ammonium ChlorideAmmonium Chloride affects the expression of IDH1 mRNA16483693
C023650anilineaniline results in increased nitrosation of IDH1 protein21708182
D001151ArsenicArsenic affects the methylation of IDH1 gene25304211
C005948astaxanthineastaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA]16964424
D001379AzathioprineAzathioprine results in decreased expression of IDH1 mRNA22623647
C547126AZM551248AZM551248 results in decreased expression of IDH1 mRNA22323515
D001554BenzeneBenzene affects the expression of IDH1 mRNA15878777
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of IDH1 mRNA26001963
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of IDH1 mRNA21632981
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of IDH1 mRNA22228805
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of IDH1 mRNA20127859
D004958Estradiol[Estradiol co-treated with Progesterone] results in increased expression of IDH1 mRNA20660070
D004958Estradiol[bisphenol A co-treated with Estradiol] results in decreased expression of IDH1 mRNA26496021
C044887beta-methylcholinebeta-methylcholine affects the expression of IDH1 mRNA21179406
C006780bisphenol Abisphenol A affects the expression of IDH1 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of IDH1 mRNA29275510
C006780bisphenol Abisphenol A affects the expression of IDH1 mRNA25181051
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in decreased expression of IDH1 mRNA26496021
C006780bisphenol Abisphenol A results in decreased expression of IDH1 mRNA26982218
C013418bromfenacoumbromfenacoum results in increased expression of IDH1 protein28903499
C032036bromobenzenebromobenzene metabolite binds to IDH1 protein17305373
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased activity of IDH1 protein16928893
D002104CadmiumIDH1 results in decreased susceptibility to Cadmium19944673
D002104CadmiumCadmium results in decreased activity of IDH1 protein19944673
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of IDH1 protein22941245
D019256Cadmium ChlorideCadmium Chloride affects the expression of IDH1 mRNA23828170
D019256Cadmium ChlorideCadmium Chloride results in increased expression of IDH1 protein24527689
D002737ChloropreneChloroprene results in increased expression of IDH1 mRNA23125180
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of IDH1 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IDH1 mRNA]17585979
D002994ClofibrateClofibrate results in increased expression of IDH1 protein16470657
C018021cobaltous chloridecobaltous chloride results in decreased expression of IDH1 mRNA16990490
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of IDH1 mRNA20971185
D003300CopperCopper affects the expression of IDH1 protein17192175
D019327Copper SulfateCopper Sulfate results in decreased expression of IDH1 mRNA19549813
C007164cumene hydroperoxidecumene hydroperoxide results in increased activity of IDH1 protein16928893
C029892cupric chloridecupric chloride results in decreased expression of IDH1 protein19616320
C057862cyanoginosin LRcyanoginosin LR results in decreased expression of IDH1 mRNA17383702
D016572CyclosporineCyclosporine results in decreased expression of IDH1 mRNA21163907|2556210
D016572CyclosporineCyclosporine results in increased expression of IDH1 mRNA27989131
D003671DEET[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IDH1 mRNA28659758
D003907Dexamethasone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of IDH1 mRNA16054899
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of IDH1 mRNA21266533|2174549
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of IDH1 mRNA27392435
D002945CisplatinCisplatin results in increased expression of IDH1 mRNA27392435
D002945Cisplatin[Cisplatin co-treated with Lutein] results in decreased expression of IDH1 mRNA24865317
D002945CisplatinCisplatin results in decreased expression of IDH1 mRNA24865317
D002945CisplatinCisplatin results in increased expression of IDH1 mRNA22023808
C000944dicrotophosdicrotophos results in decreased expression of IDH1 mRNA28302478
D004041Dietary FatsDietary Fats results in decreased expression of IDH1 mRNA18042831
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in increased expression of IDH1 mRNA27638505
D004121Dimethyl SulfoxideDimethyl Sulfoxide results in increased expression of IDH1 mRNA22169935
D004147DioxinsDioxins affects the expression of IDH1 mRNA20463971
C015854estradiol valerateestradiol valerate results in decreased expression of IDH1 mRNA15972882
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IDH1 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of IDH1 mRNA17108234
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of IDH1 mRNA23649840
D005411Flame RetardantsFlame Retardants results in decreased expression of IDH1 protein18550172
D005411Flame RetardantsFlame Retardants results in increased expression of IDH1 protein18550172
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in decreased expression of IDH1 mRNA28329830
D005485FlutamideFlutamide results in decreased expression of IDH1 mRNA21126777
D005485FlutamideFlutamide results in decreased expression of IDH1 mRNA24793618
D005485FlutamideFlutamide results in increased expression of IDH1 mRNA19299419|2152539
D005485FlutamideFlutamide results in increased expression of IDH1 protein17311803
D005944GlucosamineGlucosamine results in increased expression of IDH1 mRNA17178593
D006046GoldGold analog results in decreased expression of and results in increased phosphorylation of IDH1 protein24780912
D017313FenretinideFenretinide affects the expression of IDH1 mRNA16570282
D006820Hyaluronic AcidHyaluronic Acid analog results in decreased expression of IDH1 protein23178681
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of IDH1 protein23178681
C492448ICG 001ICG 001 results in increased expression of IDH1 mRNA26191083
D007093ImidazolesImidazoles binds to and results in decreased activity of IDH1 protein mutant form25391653
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of IDH1 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of IDH1 mRNA16054899
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of IDH1 mRNA27392435
C544151jinfukangjinfukang results in increased expression of IDH1 mRNA27392435
C410337K 7174K 7174 results in decreased expression of IDH1 mRNA24086573
D007649KetamineKetamine results in decreased expression of IDH1 mRNA20080153
C045463leflunomideleflunomide results in decreased expression of IDH1 mRNA19751817
D001556LindaneLindane affects the expression of IDH1 mRNA17785943
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IDH1 mRNA19339665
D008070Lipopolysaccharidesmethyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IDH1 mRNA]19339665
D008095Lithocholic AcidLithocholic Acid results in decreased expression of IDH1 mRNA20359477
D014975Lutein[Cisplatin co-treated with Lutein] results in decreased expression of IDH1 mRNA24865317
D014975LuteinLutein results in decreased expression of IDH1 mRNA24865317
D017258Medroxyprogesterone AcetateMedroxyprogesterone Acetate results in increased expression of IDH1 mRNA20843944
C008435methyldithiocarbamatemethyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IDH1 mRNA]19339665
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of IDH1 mRNA23103053
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of IDH1 mRNA28001369
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of IDH1 mRNA20061341
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of IDH1 protein26558463
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of IDH1 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of IDH1 mRNA"20188158
D008777MethyltestosteroneMethyltestosterone results in decreased expression of IDH1 mRNA29191790
D015741MetriboloneMetribolone results in increased expression of IDH1 protein17152098
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of IDH1 mRNA22401849
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of IDH1 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of IDH1 mRNA"25620056
C051752nefazodonenefazodone results in increased expression of IDH1 mRNA24136188
D009532NickelNickel results in decreased expression of IDH1 mRNA23195993|2476865
C119536nickel acetatenickel acetate affects the expression of IDH1 mRNA23828170
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in decreased expression of IDH1 mRNA17616710
C002741N-nitrosomorpholineN-nitrosomorpholine results in decreased expression of IDH1 protein19716841
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of IDH1 mRNA20971185
D010126OzoneOzone results in decreased expression of IDH1 mRNA16183385
D000073878Palm OilPalm Oil results in decreased expression of IDH1 mRNA18042831
D010269ParaquatAPOD protein affects the reaction [Paraquat results in decreased expression of IDH1 mRNA]21688324
D010269ParaquatParaquat results in decreased expression of IDH1 mRNA21688324
C000610380p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane"p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane results in decreased expression of IDH1 protein"26035713
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of IDH1 protein18550172
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of IDH1 protein18550172
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of IDH1 mRNA23948077
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of IDH1 protein19954255
D026023Permethrin[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IDH1 mRNA28659758
D010634PhenobarbitalPhenobarbital results in decreased expression of IDH1 protein19952500
D010636PhenolsPhenols binds to and results in decreased activity of IDH1 protein mutant form25391653
D010795Phthalic AcidsPhthalic Acids results in decreased expression of IDH1 mRNA15728792
C006253pirinixic acidpirinixic acid results in increased expression of IDH1 mRNA17426115|1830175
D010936Plant ExtractsPlant Extracts results in increased expression of IDH1 mRNA23557933
D011192Potassium DichromatePotassium Dichromate results in increased expression of IDH1 protein23718831
D011374ProgesteroneProgesterone results in increased expression of IDH1 mRNA23018184
D011374Progesterone[Estradiol co-treated with Progesterone] results in increased expression of IDH1 mRNA20660070
D011374ProgesteroneProgesterone results in increased expression of IDH1 mRNA18070364
D011374ProgesteroneProgesterone results in increased expression of IDH1 mRNA19690047
D011441PropylthiouracilPropylthiouracil results in increased expression of IDH1 mRNA24780913
C010313pseudocumenepseudocumene results in decreased expression of IDH1 protein17337753
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IDH1 mRNA28659758
D011794QuercetinQuercetin results in decreased expression of IDH1 mRNA21632981
D015474IsotretinoinIsotretinoin results in decreased expression of IDH1 mRNA20436886
C089730rosiglitazone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of IDH1 mRNA16054899
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of IDH1 mRNA25895662
D012834SilverSilver results in decreased expression of IDH1 mRNA19429238|2257657
C080703SK&F 83959SK&F 83959 results in increased expression of IDH1 protein25852303
C009277sodium arsenatesodium arsenate results in increased expression of IDH1 mRNA23922661
C017947sodium arsenitesodium arsenite results in decreased expression of IDH1 mRNA28595984
C017947sodium arsenitesodium arsenite results in increased expression of IDH1 mRNA22714537
C016104sodium bichromatesodium bichromate results in decreased expression of IDH1 mRNA24612858
D012999SomanSoman results in decreased expression of IDH1 mRNA19281266
D053260SootSoot results in decreased expression of IDH1 mRNA26551751
D053260SootSoot results in increased expression of IDH1 mRNA21914721
D014284TriiodothyronineTriiodothyronine results in increased expression of IDH1 mRNA15953391
D013605T-2 ToxinT-2 Toxin results in decreased expression of IDH1 mRNA26141394
C020806tetrabromobisphenol Atetrabromobisphenol A affects the expression of IDH1 mRNA18976794
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of IDH1 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with EGF protein] results in decreased expression of IDH1 mRNA16054899
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IDH1 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IDH1 mRNA16054899
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of IDH1 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of IDH1 mRNA15644576
D013752TetracyclineTetracycline results in decreased expression of IDH1 mRNA24489787
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of IDH1 mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of IDH1 protein22609517
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of IDH1 mRNA28111298
D014212TretinoinIDH1 protein affects the reaction [Tretinoin results in increased expression of ITGAM protein]26951332
D014212TretinoinIDH1 protein affects the susceptibility to Tretinoin26951332
D014212Tretinoin[IDH1 protein affects the susceptibility to Tretinoin] which affects the cleavage of CASP3 protein26951332
D014212Tretinoin[IDH1 protein affects the susceptibility to Tretinoin] which affects the cleavage of PARP1 protein26951332
D014212Tretinoin[IDH1 protein affects the susceptibility to Tretinoin] which affects the expression of BCL2 protein26951332
D014212Tretinoin[IDH1 protein affects the susceptibility to Tretinoin] which affects the expression of ITGAM protein26951332
D014212TretinoinTretinoin results in increased expression of IDH1 mRNA23830798
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate affects the expression of IDH1 mRNA"26179874
C057693troglitazonetroglitazone results in increased expression of IDH1 protein21315101
C057693troglitazone[troglitazone co-treated with TNF protein] results in decreased expression of IDH1 mRNA12732648
D001335Vehicle EmissionsVehicle Emissions affects the methylation of IDH1 gene25560391
C025643vinclozolinvinclozolin results in decreased expression of IDH1 mRNA21126777
C025643vinclozolinvinclozolin results in increased expression of IDH1 mRNA22570695
D015032ZincZinc results in increased expression of IDH1 mRNA17074742
D019287Zinc SulfateZinc Sulfate results in increased expression of IDH1 mRNA17074742

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000287magnesium ion binding-IDA19935646  
GO:0004450isocitrate dehydrogenase (NADP+) activity-EXP15173171  19935646  
GO:0004450isocitrate dehydrogenase (NADP+) activity-IDA10521434  19935646  20171178  
GO:0005102signaling receptor binding-IPI20178365  
GO:0042802identical protein binding-IPI19935646  21516116  26436839  
GO:0042803protein homodimerization activity-IPI19935646  
GO:0045296cadherin binding-HDA25468996  
GO:0050661NADP binding-IEA-  
GO:0051287NAD binding-IEA-  
GO:0051990(R)-2-hydroxyglutarate dehydrogenase activity-EXP19935646  
GO ID GO Term Qualifier Evidence PubMed
GO:0006097glyoxylate cycle-IEA-  
GO:0006099tricarboxylic acid cycle-IEA-  
GO:0006102isocitrate metabolic process-IDA10521434  19935646  20171178  
GO:00061032-oxoglutarate metabolic process-IDA19935646  
GO:00061032-oxoglutarate metabolic process-TAS-  
GO:0006625protein targeting to peroxisome-TAS-  
GO:0006740NADPH regeneration-TAS-  
GO:0006749glutathione metabolic process-IEA-  
GO:0006979response to oxidative stress-IEA-  
GO:0008585female gonad development-IEA-  
GO:0043312neutrophil degranulation-TAS-  
GO:0048545response to steroid hormone-IEA-  
GO:0060696regulation of phospholipid catabolic process-IEA-  
GO:0071071regulation of phospholipid biosynthetic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005737cytoplasm-IDA-  
GO:0005739mitochondrion-IEA-  
GO:0005777peroxisome-IDA10521434  
GO:0005782peroxisomal matrix-TAS-  
GO:0005829cytosol-IDA10521434  
GO:0005829cytosol-TAS-  
GO:0034774secretory granule lumen-TAS-  
GO:0070062extracellular exosome-HDA19056867  23533145  
GO:1904724tertiary granule lumen-TAS-  
GO:1904813ficolin-1-rich granule lumen-TAS-  
KEGG ID KEGG Term
hsa00020Citrate cycle (TCA cycle)
hsa00480Glutathione metabolism
hsa01100Metabolic pathways
hsa04146Peroxisome
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-1643685DiseaseTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-196854Metabolism of vitamins and cofactorsTAS
R-HSA-2978092Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarateTAS
R-HSA-389542NADPH regenerationTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-392499Metabolism of proteinsIEA
R-HSA-5668914Diseases of metabolismTAS
R-HSA-6798695Neutrophil degranulationTAS
R-HSA-8978934Metabolism of cofactorsTAS
R-HSA-9033241Peroxisomal protein importTAS
R-HSA-9033241Peroxisomal protein importIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29723602Non-small cell lung cancers with Isocitrate dehydrogenase 1 or 2 (IDH1/2) mutations. (2018 Apr 30)Toth LNHum Pathol
26464434Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites. (2016 Feb 18)Lee STNucleic Acids Res
29246019Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study. (2017 Nov 21)Liu ROncotarget
20301715Hereditary Paraganglioma-Pheochromocytoma Syndromes (1993)Kirmani S-