Gene: NANOS3

342977
NANOS1L|NOS3|ZC2HC12C
nanos C2HC-type zinc finger 3
protein-coding
19p13.12
Ensembl:ENSG00000187556 MIM:608229 Vega:OTTHUMG00000181850 UniprotKB:P60323
NC_000019.10
PubMed
0   ANCO-SNPs
ND|AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.023e-1 (AD)  1.922e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FXYD70.767
ARHGDIG0.763
TTC9B0.745
FAM173A0.741
CISD30.736
TFPT0.727
C9orf160.726
CHCHD100.726
USE10.724
LAGE30.719

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.487
OR4F29-0.475
UPK1B-0.467
KLHL31-0.435
ATP11C-0.423
LEPR-0.42
TNFRSF8-0.42
SMC4-0.416
LY75-0.413
AASS-0.411

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of NANOS3 mRNA"18648102
D000082AcetaminophenAcetaminophen results in decreased expression of NANOS3 mRNA22230336
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of NANOS3 mRNA24449571
C006780bisphenol Abisphenol A affects the expression of NANOS3 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of NANOS3 mRNA25181051
D002066BusulfanBusulfan results in decreased expression of NANOS3 mRNA26524245
C017160cypermethrincypermethrin results in decreased expression of NANOS3 mRNA24810582
D004026DieldrinDieldrin results in increased expression of NANOS3 mRNA20438755
D004041Dietary FatsDietary Fats results in increased expression of NANOS3 mRNA25016146
D011374ProgesteroneProgesterone results in decreased expression of NANOS3 mRNA19690047
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of NANOS3 mRNA28065790
D014212TretinoinTretinoin results in decreased expression of NANOS3 mRNA23724009

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-ISS-  
GO:0005515protein binding-IPI24736845  
GO:0008270zinc ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006417regulation of translation-ISS-  
GO:0007275multicellular organism development-IEA-  
GO:0007281germ cell development-IMP21421998  
GO:0007283spermatogenesis-ISS-  
GO:0017148negative regulation of translation-IDA24736845  
GO:0048477oogenesis-IEA-  
GO:0051726regulation of cell cycle-ISS-  
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-IDA24736845  
GO:2001234negative regulation of apoptotic signaling pathway-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000932P-body-ISS-  
GO:0005634nucleus-IDA21421998  
GO:0005737cytoplasm-IDA21421998  
GO:0010494cytoplasmic stress granule-ISS-  
GO:0048471perinuclear region of cytoplasm-IDA22899867  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal