Gene: IFIT3

3437
CIG-49|GARG-49|IFI60|IFIT4|IRG2|ISG60|P60|RIG-G|cig41
interferon induced protein with tetratricopeptide repeats 3
protein-coding
10q23.31
Ensembl:ENSG00000119917 MIM:604650 Vega:OTTHUMG00000018708 UniprotKB:O14879
NC_000010.11
PubMed
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.639e-1 (AD)  5.636e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg06188083chr10:91093005IFIT39.990e-10Alcohol consumption per day27843151

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DDX580.888
USP180.882
IFIH10.854
OAS30.85
OASL0.841
RTP40.839
OAS10.83
DDX600.829
IFIT20.826
MX10.822

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.328
OR4F5-0.328
SYNGR4-0.189
RHO-0.188
EPPIN-0.17
MAGEB17-0.154
LOXHD1-0.152
ASB18-0.149
KCNG2-0.146
DCSTAMP-0.144

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0700461,2-dioleoyloxy-3-(trimethylammonium)propane"[Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of IFIT3 mRNA"22129739
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of IFIT3 mRNA"23146750
C0261142-xylene2-xylene results in increased expression of IFIT3 mRNA20359517
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFIT3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFIT3 mRNA"27188386
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of IFIT3 mRNA19191707
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFIT3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFIT3 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of IFIT3 mRNA21420995
D000082AcetaminophenAcetaminophen results in increased expression of IFIT3 mRNA26690555
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of IFIT3 mRNA17585979
D000082AcetaminophenMAP3K5 protein affects the reaction [Acetaminophen results in increased expression of IFIT3 mRNA]18700144
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IFIT3 mRNA]17585979
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of IFIT3 mRNA27153756
D001104ArbutinArbutin results in decreased expression of IFIT3 mRNA17103032
C006632arsenic trioxide[Tretinoin co-treated with arsenic trioxide] results in increased expression of IFIT3 mRNA15894607
D016589AstemizoleAstemizole results in decreased expression of IFIT3 mRNA20221588
D001379AzathioprineAzathioprine results in decreased expression of IFIT3 mRNA19192274
C487081belinostatbelinostat results in decreased expression of IFIT3 mRNA27188386
C030935benz(a)anthracenebenz(a)anthracene results in decreased expression of IFIT3 mRNA26377693
D001554BenzeneBenzene results in increased expression of IFIT3 mRNA20359517
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of IFIT3 mRNA19152381
D001564Benzo(a)pyrenechlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of IFIT3 mRNA]19152381
D001564Benzo(a)pyreneAHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of IFIT3 mRNA]15034205
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of IFIT3 mRNA20713471
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of IFIT3 mRNA15034205|2373587
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of IFIT3 mRNA"20018196
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of IFIT3 mRNA19619570
D004958EstradiolEstradiol results in increased expression of IFIT3 mRNA19619570|2118537
D004958EstradiolEstradiol results in increased expression of IFIT3 mRNA15289156
C006780bisphenol Abisphenol A results in increased expression of IFIT3 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of IFIT3 gene28505145
C518299BIX 01294BIX 01294 promotes the reaction [IFNA2 protein alternative form results in increased expression of IFIT3 mRNA]25079219
C518299BIX 01294BIX 01294 promotes the reaction [IFNA2 protein results in increased expression of IFIT3 mRNA]25079219
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of IFIT3 mRNA14729362|1500399
C018475butyraldehydebutyraldehyde results in decreased expression of IFIT3 mRNA26079696
D002087Butyrates[Tretinoin co-treated with Butyrates] results in increased expression of IFIT3 mRNA12130515
C584509C646 compoundC646 compound results in increased expression of IFIT3 mRNA26191083
D019256Cadmium ChlorideCadmium Chloride results in increased expression of IFIT3 mRNA24982889
D019256Cadmium ChlorideCadmium Chloride results in increased expression of IFIT3 mRNA25993096
C007020chlorophyllinchlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of IFIT3 mRNA]19152381
D002784Cholesterol"[Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of IFIT3 mRNA"22129739
D007464Clioquinol[Clioquinol binds to Copper] which results in decreased expression of IFIT3 protein18346929
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of IFIT3 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IFIT3 mRNA]17585979
D003300Copper[Clioquinol binds to Copper] which results in decreased expression of IFIT3 protein18346929
D003300Copper[Disulfiram binds to Copper] which results in increased expression of IFIT3 mRNA24690739
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of IFIT3 mRNA20971185
D016572CyclosporineCyclosporine results in decreased expression of IFIT3 mRNA25562108
D016572CyclosporineCyclosporine results in increased expression of IFIT3 mRNA22147139
D000069439DasatinibDasatinib results in increased expression of IFIT3 mRNA23825585
D003703DemecolcineDemecolcine results in increased expression of IFIT3 mRNA23649840
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of IFIT3 mRNA28962523
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of IFIT3 mRNA27392435
D002945CisplatinCisplatin results in increased expression of IFIT3 mRNA27392435
D004008DiclofenacDiclofenac results in decreased expression of IFIT3 mRNA19192274
D004041Dietary FatsDietary Fats affects the expression of IFIT3 mRNA17086191
D004041Dietary Fatsresveratrol inhibits the reaction [Dietary Fats affects the expression of IFIT3 mRNA]17086191
D004041Dietary FatsDietary Fats results in decreased expression of IFIT3 mRNA21852083
C014476diethyl maleatediethyl maleate results in decreased expression of IFIT3 mRNA21161181
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of IFIT3 mRNA15289156
D002117CalcitriolCalcitriol results in decreased expression of IFIT3 mRNA16002434
C472511dimethylarsinous aciddimethylarsinous acid results in increased expression of IFIT3 mRNA20886546
D0198131,2-Dimethylhydrazine"1,2-Dimethylhydrazine results in increased expression of IFIT3 mRNA"27840820
D0198131,2-Dimethylhydrazine"APC protein affects the reaction [1,2-Dimethylhydrazine results in increased expression of IFIT3 mRNA]"27840820
D004221Disulfiram[Disulfiram binds to Copper] which results in increased expression of IFIT3 mRNA24690739
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IFIT3 mRNA22079256
C004912ethylbenzeneethylbenzene results in increased expression of IFIT3 mRNA20359517
C024565ethylene dichlorideethylene dichloride results in decreased expression of IFIT3 mRNA28189721
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of IFIT3 mRNA23649840
D005485FlutamideFlutamide results in increased expression of IFIT3 mRNA24793618
D005557FormaldehydeFormaldehyde results in decreased expression of IFIT3 mRNA28937961
D005557FormaldehydeFormaldehyde results in increased expression of IFIT3 mRNA23649840
C064925gadodiamidegadodiamide results in increased expression of IFIT3 mRNA20959327
C007834genipingenipin inhibits the reaction [Lipopolysaccharides results in increased expression of IFIT3 mRNA]22687549
D019833GenisteinGenistein results in increased expression of IFIT3 mRNA15289156
D005944GlucosamineGlucosamine results in increased expression of IFIT3 mRNA17178593
D006052Gold Sodium ThiomalateGold Sodium Thiomalate results in decreased expression of IFIT3 mRNA19192274
C014026hexamethylene bisacetamide[Tretinoin co-treated with hexamethylene bisacetamide] results in increased expression of IFIT3 mRNA12130515
D017313FenretinideFenretinide results in decreased expression of IFIT3 mRNA28973697
C492448ICG 001ICG 001 results in increased expression of IFIT3 mRNA26191083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of IFIT3 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of IFIT3 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of IFIT3 mRNA24796395|2675264
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of IFIT3 mRNA"15522845
D008070LipopolysaccharidesLipopolysaccharides affects the expression of IFIT3 mRNA28070326
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IFIT3 mRNA15860229
D008070LipopolysaccharidesPlant Extracts affects the reaction [Lipopolysaccharides affects the expression of IFIT3 mRNA]28070326
D008070Lipopolysaccharidesgenipin inhibits the reaction [Lipopolysaccharides results in increased expression of IFIT3 mRNA]22687549
D008070LipopolysaccharidesLipopolysaccharides affects the expression of IFIT3 mRNA24056979
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IFIT3 mRNA22687549|2658214
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT3 mRNA]24056979
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in increased expression of IFIT3 mRNA21641980
D008727MethotrexateMethotrexate results in decreased expression of IFIT3 mRNA19192274
D008748MethylcholanthreneMethylcholanthrene results in decreased expression of IFIT3 mRNA20713471
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT3 mRNA]24056979
D008752Methylene ChlorideMethylene Chloride results in increased expression of IFIT3 mRNA20359517
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of IFIT3 mRNA28001369
D008775MethylprednisoloneMethylprednisolone results in decreased expression of IFIT3 mRNA19192274
D009151Mustard GasMustard Gas results in increased expression of IFIT3 mRNA25102026
C510788N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine"N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine results in decreased expression of IFIT3 mRNA"25487280
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of IFIT3 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of IFIT3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of IFIT3 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of IFIT3 mRNA"25554681
D009532NickelNickel results in increased expression of IFIT3 mRNA24768652|2558310
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of IFIT3 mRNA20971185
C558013NSC 689534NSC 689534 results in increased expression of IFIT3 mRNA20971185
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of IFIT3 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of IFIT3 mRNA25729387
D010081OxazoloneOxazolone results in increased expression of IFIT3 mRNA21893156
D010126OzoneOzone results in decreased expression of IFIT3 mRNA16183385
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of IFIT3 mRNA26705709
D010416PentachlorophenolPentachlorophenol results in increased expression of IFIT3 mRNA23892564
D010634PhenobarbitalPhenobarbital affects the expression of IFIT3 mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFIT3 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of IFIT3 mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of IFIT3 mRNA23811191
C006253pirinixic acidpirinixic acid results in increased expression of IFIT3 mRNA17426115
D010936Plant ExtractsPlant Extracts affects the reaction [Lipopolysaccharides affects the expression of IFIT3 mRNA]28070326
D010936Plant ExtractsPlant Extracts results in increased expression of IFIT3 mRNA21297082
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls affects the expression of IFIT3 mRNA21334430
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IFIT3 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of IFIT3 mRNA22079256
D011205Povidone[Silver analog co-treated with Povidone] results in decreased expression of IFIT3 mRNA25194297
D011239PrednisolonePrednisolone results in decreased expression of IFIT3 mRNA19192274
D011374Progesterone[Progesterone co-treated with TGFB1 protein] results in increased expression of IFIT3 mRNA21768398
D011374ProgesteroneProgesterone results in increased expression of IFIT3 mRNA21768398
D011374ProgesteroneProgesterone results in increased expression of IFIT3 mRNA19690047
C045950propiconazolepropiconazole results in increased expression of IFIT3 mRNA21278054
C059514resveratrolresveratrol inhibits the reaction [Dietary Fats affects the expression of IFIT3 mRNA]17086191
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of IFIT3 mRNA"24160326
D012822Silicon DioxideSilicon Dioxide results in increased expression of IFIT3 mRNA25351596
D012822Silicon DioxideSilicon Dioxide results in increased expression of IFIT3 mRNA26345256
D012834Silver[Silver analog co-treated with Povidone] results in decreased expression of IFIT3 mRNA25194297
D012999SomanSoman results in increased expression of IFIT3 mRNA19281266
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in increased expression of IFIT3 mRNA21641980
C061133tamibarotenetamibarotene results in increased expression of IFIT3 mRNA15498508
D013629TamoxifenTamoxifen results in increased expression of IFIT3 mRNA19155303
D013629TamoxifenTamoxifen affects the expression of IFIT3 mRNA20937368
C004648testosterone enanthatetestosterone enanthate affects the expression of IFIT3 mRNA17440010
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of IFIT3 mRNA27914987
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of IFIT3 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IFIT3 mRNA19619570
D013749TetrachlorodibenzodioxinAHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IFIT3 mRNA]15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of IFIT3 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IFIT3 mRNA15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of IFIT3 mRNA17337447
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of IFIT3 mRNA22298810
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of IFIT3 mRNA25613284
D013876ThiophenesThiophenes analog promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA]16140954
C009495titanium dioxidetitanium dioxide results in increased expression of IFIT3 mRNA23557971|2776080
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of IFIT3 mRNA28065790
C479163tofacitinibtofacitinib results in decreased expression of IFIT3 mRNA25487280
D014050TolueneToluene results in increased expression of IFIT3 mRNA20359517
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of IFIT3 mRNA25729387
D019772TopotecanTopotecan results in increased expression of IFIT3 mRNA25729387
D014212TretinoinThiophenes analog promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA]16140954
D014212TretinoinTretinoin affects the expression of IFIT3 mRNA15498508
D014212Tretinoin[Tretinoin co-treated with arsenic trioxide] results in increased expression of IFIT3 mRNA15894607
D014212Tretinoin[Tretinoin co-treated with Butyrates] results in increased expression of IFIT3 mRNA12130515
D014212Tretinoin[Tretinoin co-treated with hexamethylene bisacetamide] results in increased expression of IFIT3 mRNA12130515
D014212TretinoinTretinoin results in increased expression of IFIT3 mRNA12130515|1589460
D014212TretinoinTretinoin results in increased expression of IFIT3 protein15059897
D014241TrichloroethyleneTrichloroethylene results in increased expression of IFIT3 mRNA20359517
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFIT3 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of IFIT3 mRNA24935251|2627250
C561310UNC 0638UNC 0638 promotes the reaction [IFNA2 protein alternative form results in increased expression of IFIT3 mRNA]25079219
D014635Valproic AcidValproic Acid affects the expression of IFIT3 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of IFIT3 mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of IFIT3 mRNA19949822|2800136
D014640VancomycinVancomycin results in decreased expression of IFIT3 mRNA18930951
D001335Vehicle EmissionsVehicle Emissions affects the expression of IFIT3 mRNA23940539
D024483Vitamin K 3Vitamin K 3 affects the expression of IFIT3 mRNA20829426
D015032ZincZinc deficiency results in increased expression of IFIT3 mRNA19111725
D015032ZincZinc inhibits the reaction [Zinc deficiency results in increased expression of IFIT3 mRNA]19111725

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003674molecular_function-ND-  
GO:0003723RNA binding-IBA21873635  
GO:0005515protein binding-IPI16189514  17050680  21163940  21190939  21516116  21642987  
21813773  25416956  25910212  27107012  27107014  
GO:0042802identical protein binding-IPI16189514  21163940  21642987  
GO ID GO Term Qualifier Evidence PubMed
GO:0008285negative regulation of cell proliferation-IDA17050680  
GO:0009615response to virus-IMP21642987  
GO:0035457cellular response to interferon-alpha-IEA-  
GO:0043066negative regulation of apoptotic process-IDA21190939  
GO:0051607defense response to virus-IBA21873635  
GO:0060337type I interferon signaling pathway-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IDA17050680  18706081  
GO:0005739mitochondrion-IDA21813773  
GO:0005829cytosol-IBA21873635  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-168256Immune SystemTAS
R-HSA-909733Interferon alpha/beta signalingTAS
R-HSA-913531Interferon SignalingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26927796POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes. (2016 Apr 1)Zhou HJ Immunol
26917578Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12. (2016 Jun)Jackson VEThorax