Gene: SOWAHB

345079
ANKRD56
sosondowah ankyrin repeat domain family member B
protein-coding
4q21.1
Ensembl:ENSG00000186212 Vega:OTTHUMG00000160876 UniprotKB:A6NEL2
NC_000004.12
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.008e-1 (AD)  4.741e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2703126chr4:76898689 (GRCh38.p7)T>Cnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PTPN30.947
HECW10.945
STXBP5L0.944
FRMPD40.943
OPN30.942
CDH180.941
SCN8A0.939
C3orf800.938
C1QL30.936
NELL10.935

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RAB13-0.648
HEY2-0.627
ROM1-0.616
HVCN1-0.608
AKR1C3-0.601
YES1-0.596
CHST14-0.592
RNF135-0.588
HEBP2-0.588
MYL3-0.577

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen affects the expression of SOWAHB mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of SOWAHB gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SOWAHB mRNA19770486
D001151ArsenicArsenic affects the methylation of SOWAHB gene25304211
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased mutagenesis of SOWAHB gene25435355
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SOWAHB mRNA19770486
C006780bisphenol Abisphenol A results in decreased expression of SOWAHB mRNA25181051
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of SOWAHB mRNA21457566
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of SOWAHB mRNA27339419
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SOWAHB mRNA20938992
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of SOWAHB mRNA21266533
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of SOWAHB mRNA27776689
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SOWAHB mRNA20938992
C039281furanfuran results in increased expression of SOWAHB mRNA24183702
D017313FenretinideFenretinide results in increased expression of SOWAHB mRNA28973697
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SOWAHB mRNA20938992
C523799MRK 003SOWAHB results in decreased susceptibility to MRK 00319903844
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of SOWAHB mRNA"29244179
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of SOWAHB mRNA"25620056
C028007nickel monoxidenickel monoxide results in decreased expression of SOWAHB mRNA19167457
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of SOWAHB mRNA]19482888
D010634PhenobarbitalPhenobarbital results in decreased expression of SOWAHB mRNA19270015
D010634PhenobarbitalPhenobarbital results in increased expression of SOWAHB mRNA19270015|1948288
D011441PropylthiouracilPropylthiouracil results in decreased expression of SOWAHB mRNA24780913
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SOWAHB mRNA26377647
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SOWAHB promoter]19654925
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of SOWAHB mRNA20133372
D014520UrethaneUrethane results in decreased expression of SOWAHB mRNA28818685
D014635Valproic AcidValproic Acid results in decreased methylation of SOWAHB gene29154799
D014635Valproic AcidValproic Acid affects the expression of SOWAHB mRNA17963808

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal