Gene: GATD1

347862
PDDC1
glutamine amidotransferase like class 1 domain containing 1
protein-coding
11p15.5
Ensembl:ENSG00000177225 Vega:OTTHUMG00000133315 UniprotKB:Q8NB37
NC_000011.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.559e-1 (AD)  1.647e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7930569chr11:771034 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of GATD1 mRNA"21346803
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of GATD1 mRNA27153756
D001280AtrazineAtrazine results in decreased expression of GATD1 mRNA22378314
C044887beta-methylcholinebeta-methylcholine affects the expression of GATD1 mRNA21179406
C006780bisphenol Abisphenol A results in increased expression of GATD1 mRNA25181051
C018021cobaltous chloridecobaltous chloride results in decreased expression of GATD1 mRNA19320972
D003976DiazinonDiazinon results in increased methylation of GATD1 gene22964155
C412815GW 4064GW 4064 promotes the reaction [NR1H4 protein binds to GATD1 gene]20091679
C544151jinfukangjinfukang results in increased expression of GATD1 mRNA27392435
D007854LeadLead results in decreased expression of GATD1 mRNA19921347
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GATD1 mRNA17961207
C568376MT19c compoundMT19c compound results in decreased expression of GATD1 mRNA21781307
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GATD1 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GATD1 mRNA21570461
D014212TretinoinTretinoin results in decreased expression of GATD1 mRNA23724009

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003674molecular_function-ND-  
GO ID GO Term Qualifier Evidence PubMed
GO:0008150biological_process-ND-  
GO ID GO Term Qualifier Evidence PubMed
GO:0070062extracellular exosome-HDA19056867  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal