Gene: RAET1G

353091
ULBP5
retinoic acid early transcript 1G
protein-coding
6q25.1
Ensembl:ENSG00000203722 MIM:609244 Vega:OTTHUMG00000015802 UniprotKB:Q6H3X3
NC_000006.12
SNP Mapped
1   ANCO-SNPs
AD
0   
8.604e-1 (AD)  5.889e-1 (ND)   (Frontal_Cortex)
4.455e-1 (AD)  8.683e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs17079029chr6:149918194 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
VSIG100.484
RNPEP0.471
ZNF7000.463
ZNF6620.458
DNMBP0.451
P2RX40.447
C2CD20.447
PILRA0.446
HSPBAP10.441
RIPK10.44

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TMEM114-0.235
SLC27A6-0.227
OR4F5-0.205
OR4F29-0.199
UCN3-0.182
TH-0.179
RNASE8-0.176
C5orf64-0.174
PRSS33-0.173
PNMA6A-0.172

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of RAET1G mRNA14729362
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of RAET1G mRNA22079256
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of RAET1G mRNA14729362
D009151Mustard GasMustard Gas results in increased expression of RAET1G mRNA25102026
D010936Plant ExtractsPlant Extracts results in decreased expression of RAET1G mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of RAET1G mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of RAET1G mRNA22079256

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI15240696  18544572  19424970  19658097  
GO:0046703natural killer cell lectin-like receptor binding-IBA21873635  
GO:0046703natural killer cell lectin-like receptor binding-IPI15240696  
GO ID GO Term Qualifier Evidence PubMed
GO:0001913T cell mediated cytotoxicity-IBA21873635  
GO:0002729positive regulation of natural killer cell cytokine production-IDA18544572  
GO:0006955immune response-IBA21873635  
GO:0016032viral process-IEA-  
GO:0030101natural killer cell activation-IBA21873635  
GO:0042267natural killer cell mediated cytotoxicity-IBA21873635  
GO:0042267natural killer cell mediated cytotoxicity-IDA15240696  
GO:0042271susceptibility to natural killer cell mediated cytotoxicity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005783endoplasmic reticulum-IEA-  
GO:0005886plasma membrane-IBA21873635  
GO:0005886plasma membrane-NAS15240696  
GO:0005886plasma membrane-TAS-  
GO:0016021integral component of membrane-IEA-  
GO:0031225anchored component of membrane-IEA-  
KEGG ID KEGG Term
hsa04650Natural killer cell mediated cytotoxicity
Reactome ID Reactome Term Evidence
R-HSA-163125Post-translational modification: synthesis of GPI-anchored proteinsTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-597592Post-translational protein modificationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal