Gene: IL1A

3552
IL-1A|IL1|IL1-ALPHA|IL1F1
interleukin 1 alpha
protein-coding
2q14.1
Ensembl:ENSG00000115008 MIM:147760 Vega:OTTHUMG00000131315 UniprotKB:P01583
NG_008850.1
PubMed
ND|AD
14   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.859e-1 (AD)  3.827e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
IL1B0.764
OLR10.76
CCL40.683
CCL30.675
OSM0.639
C5AR10.637
PLEK0.635
CH25H0.633
GPR1830.63
TNFAIP30.616

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TEX38-0.272
THNSL2-0.269
RS1-0.249
KCNJ6-0.242
KNCN-0.229
C9orf163-0.229
C19orf73-0.225
OR2L13-0.219
AMER3-0.219
KCNA2-0.219

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB06372RilonaceptBiotechDrug501081-76-1Approved|InvestigationalTarget
ID Drug Name Action PubMed
C5348801,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane"1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]"25406165
C5452551,1-bis(3'-indolyl)-1-(p-anisyl)methane"1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]"25406165
C0256031,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [tributyltin results in increased expression of IL1A protein]"9221826
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]"15613243
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of IL1A mRNA"19162173
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]"14998300
C47781915-deoxyprostaglandin J215-deoxyprostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]10866999
C0326681-nitropyrene1-nitropyrene results in increased expression of IL1A mRNA19428942|2154030
C4001841-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of IL1A mRNA16386258
C0058492,2,2-trichloroethanol"2,2,2-trichloroethanol results in increased expression of IL1A protein"23041168
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1A mRNA]20464547
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]15728660
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]20464547
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Soot results in increased secretion of IL1A protein]19782127
C00358522-hydroxycholesterol22-hydroxycholesterol results in increased expression of IL1A mRNA19426978
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of IL1A mRNA"19114083
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of IL1A mRNA"25710175
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of IL1A mRNA"21346803
C4696832-(6-((3-(4-(diphenylmethoxy)piperidino)propyl)amino)imidazo(1,2-b)pyridazin-2-yl)-2-methylpropionic acid"2-(6-((3-(4-(diphenylmethoxy)piperidino)propyl)amino)imidazo(1,2-b)pyridazin-2-yl)-2-methylpropionic acid inhibits the reaction [Dexamethasone results in increased expression of IL1A mRNA]"12438553
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in decreased expression of IL1A protein11031321
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased expression of IL1A protein11428619
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl results in increased expression of IL1A mRNA"26519613
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1A mRNA"26519613|2835176
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]24570342
C0179063-dinitrobenzene3-dinitrobenzene results in increased expression of IL1A mRNA22841810
C0312853-xylene3-xylene results in increased expression of IL1A protein12717741|1590242
C4861844,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]"21127968
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1A mRNA]20464547
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]20464547
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]16880258
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Soot results in increased secretion of IL1A protein]19782127
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of IL1A mRNA19191707
C0729564-nitrososulfamethoxazole4-nitrososulfamethoxazole results in increased secretion of IL1A protein28444390
C0297284-phenylenediamine4-phenylenediamine results in increased expression of IL1A protein23178550
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]"15613243
C099958acanthoic acidacanthoic acid inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of IL1A mRNA]28964808
D000082AcetaminophenAcetaminophen results in increased expression of IL1A mRNA11826401|1215399
D000082AcetaminophenIFNG protein promotes the reaction [Acetaminophen results in increased expression of IL1A mRNA]12153990
D000082AcetaminophenIL10 protein affects the reaction [Acetaminophen results in increased expression of IL1A mRNA]11826401
D000082AcetaminophenIL1A protein inhibits the reaction [Acetaminophen results in increased expression of CYP1A2 protein]19002106
D000082AcetaminophenIL1A protein inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]19002106
D000082AcetaminophenIL1A protein inhibits the reaction [Acetaminophen results in increased expression of CYP3A11 protein]19002106
D000082AcetaminophenTNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL1A mRNA]14557383
D000082AcetaminophenAcetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of IL1A mRNA]19265712
D000082AcetaminophenAcetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of IL1A protein]19265712
D000111Acetylcysteine[Acetylcysteine co-treated with IL1A protein] results in increased expression of SOD2 protein7476933
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1A protein]26138014
D000111AcetylcysteineAcetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]24570342
D000111AcetylcysteineAcetylcysteine promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
D000119Acetylmuramyl-Alanyl-IsoglutamineIL1A protein results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine19897531
D020106AcrylamideAcrylamide results in decreased expression of IL1A mRNA28959563
D000255Adenosine TriphosphateAdenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]26068648
D000255Adenosine Triphosphate[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein26068648
D000255Adenosine Triphosphate"(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]]"26068648
D000255Adenosine Triphosphate"(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein]"26068648
C016601afimoxifeneafimoxifene results in decreased expression of IL1A mRNA23373633
D000393Air PollutantsAir Pollutants results in increased expression of IL1A mRNA18079490
D000393Air PollutantsAir Pollutants results in increased expression of IL1A protein27865893
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in increased expression of IL1A mRNA"23195993
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in increased secretion of IL1A protein"20005085
D015766Albendazole[Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein16861626
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Lindane results in increased expression of IL1A mRNA]15025948
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Lindane results in increased expression of IL1A protein]15025948
C104223aluminum lactatealuminum lactate results in increased expression of IL1A protein14743440
D000537Aluminum OxideAluminum Oxide results in increased expression of IL1A mRNA15183442
D019804Mesalamine[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased activity of NFE2L2 protein27818126
D019804Mesalamine[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of GCLC mRNA27818126
D019804Mesalamine[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of PPARG protein27818126
D019804MesalamineMesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein]27818126
D019804MesalamineMesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with resveratrol] results in increased expression of HMOX1 mRNA]27818126
D019804MesalamineMesalamine promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]27818126
D000638AmiodaroneAmiodarone results in increased expression of IL1A mRNA19774075
D000638Amiodarone"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone"19362101
D000643Ammonium ChlorideAmmonium Chloride affects the expression of IL1A mRNA16483693
C054105ammonium trichloro(dioxoethylene-O,O'-)tellurate"ammonium trichloro(dioxoethylene-O,O'-)tellurate results in increased secretion of IL1A protein"7498364
C054105ammonium trichloro(dioxoethylene-O,O'-)tellurate"ammonium trichloro(dioxoethylene-O,O'-)tellurate results in increased secretion of IL1A protein"7498364
C023650anilineaniline results in increased expression of IL1A mRNA15694462|1842024
C023650anilineaniline results in increased expression of IL1A protein15694462|1842024
D016718Arachidonic Acid[IL1A protein co-treated with Arachidonic Acid] results in increased abundance of Dinoprostone11351503
D001151ArsenicArsenic results in decreased expression of IL1A mRNA16835338
D001151ArsenicArsenic results in increased expression of IL1A mRNA19945496
C006632arsenic trioxidearsenic trioxide results in decreased expression of IL1A mRNA17530438
C006632arsenic trioxidearsenic trioxide results in increased expression of IL1A mRNA22521957
C015001arsenitearsenite results in decreased expression of IL1A mRNA16085347
C015001arsenitecaffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL1A mRNA]16085347
D001194AsbestosAsbestos results in decreased expression of IL1A mRNA22398240
D001194AsbestosAsbestos results in increased expression of IL1A mRNA22398240
D017636Asbestos, Amphibole"Asbestos, Amphibole results in increased expression of IL1A protein"20855422
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of IL1A mRNA"24160326|2575705
D017638Asbestos, Crocidolite"[Asbestos, Crocidolite co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA"9400719
D001241Aspirin[Aspirin co-treated with IL1A] results in increased expression of TNF mRNA14742690
D001241AspirinAspirin promotes the reaction [IL1A results in increased expression of CXCL1 mRNA]14742690
D001241AspirinAspirin promotes the reaction [IL1A results in increased expression of IL1B mRNA]14742690
D001241AspirinAspirin promotes the reaction [IL1A results in increased expression of IL6 mRNA]14742690
D001241AspirinAspirin promotes the reaction [IL1A results in increased expression of PTGS2 mRNA]14742690
D001241AspirinAspirin promotes the reaction [IL1A results in increased expression of PTGS2 protein]14742690
D001241AspirinAspirin promotes the reaction [IL1A results in increased phosphorylation of MAPK14 protein]14742690
D001241AspirinIL1A promotes the reaction [Aspirin results in increased expression of PTGS2 mRNA]14742690
D001241AspirinIL1A promotes the reaction [Aspirin results in increased expression of PTGS2 protein]14742690
D001241AspirinIL1A promotes the reaction [Aspirin results in increased phosphorylation of MAPK14 protein]14742690
D001379Azathioprine"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Azathioprine"19362101
D001397AzoxymethaneAzoxymethane results in increased expression of IL1A protein20431929
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of IL1A mRNA8156173
D001548Benzalkonium CompoundsBenzalkonium Compounds results in increased expression of IL1A mRNA12781210
D001548Benzalkonium CompoundsBenzalkonium Compounds results in increased expression of IL1A protein25290854|8006454
D001548Benzalkonium CompoundsBenzalkonium Compounds results in increased secretion of IL1A protein12781210
D001548Benzalkonium CompoundsBenzalkonium Compounds results in increased secretion of IL1A protein20937349
D001553Benzbromarone"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone"19362101
D001554BenzeneBenzene affects the expression of IL1A mRNA21147609
D001554BenzeneIL1A gene SNP affects the susceptibility to Benzene16230423
D001554BenzeneBenzene inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]1868253
D001554BenzeneBenzene results in decreased cleavage of IL1A protein9118901
D001554BenzeneIL1A protein results in decreased susceptibility to Benzene1868253
D001554BenzeneIndomethacin inhibits the reaction [Benzene inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]]1868253
D001554BenzeneBenzene results in increased expression of IL1A protein15902427
D001565BenzoatesBenzoates results in increased expression of IL1A protein23178550
D001566BenzocaineBenzocaine results in increased activity of IL1A protein15840424
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of IL1A mRNA8156173
D019324beta-Naphthoflavone[isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA21295105
D019817Benzoic AcidBenzoic Acid results in increased expression of IL1A mRNA12781210
D019817Benzoic AcidBenzoic Acid results in increased secretion of IL1A protein12781210
D001564Benzo(a)pyrene2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1A mRNA]20464547
D001564Benzo(a)pyrene4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1A mRNA]20464547
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of IL1A mRNA16002475|1787925
D001564Benzo(a)pyrenechlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1A mRNA]19152381
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of IL1A mRNA"20018196
D001585Benzoyl PeroxideBenzoyl Peroxide results in increased expression of IL1A mRNA11522381
D001585Benzoyl PeroxideBenzoyl Peroxide results in increased expression of IL1A mRNA7665919|8435107
D001585Benzoyl PeroxideBenzoyl Peroxide results in increased expression of IL1A protein10753220|7665919
D001585Benzoyl PeroxidePlant Extracts inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A mRNA]7665919
D001585Benzoyl PeroxidePlant Extracts inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A protein]7665919
D001585Benzoyl PeroxideSilymarin inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A protein]10753220
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]15728660
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]11230753
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of IL1A mRNA20061341
D004958EstradiolEstradiol inhibits the reaction [IL1A protein promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to CCL2 promoter]]10614622
D004958EstradiolEstradiol inhibits the reaction [IL1A protein results in increased expression of CCL2 mRNA]10614622
D004958EstradiolEstradiol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]10614622
D004958EstradiolEstradiol results in decreased expression of IL1A mRNA10731640
D004958Estradiolfulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]10614622
D004958Estradioldaidzein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA]11473722
D004958EstradiolEstradiol results in increased expression of IL1A mRNA11473722
D004958EstradiolGenistein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA]11473722
D004958EstradiolToremifene inhibits the reaction [Estradiol results in increased expression of IL1A mRNA]12079510
D004958EstradiolToremifene inhibits the reaction [Estradiol results in increased expression of IL1A protein]12079510
D004958EstradiolEstradiol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]21127968
D0150822,2'-Dipyridyl"2,2'-Dipyridyl inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]"24570342
C074212bis(maltolato)oxovanadium(IV)bis(maltolato)oxovanadium(IV) results in decreased expression of IL1A mRNA17696279
C006780bisphenol Abisphenol A affects the expression of IL1A mRNA20170705
C006780bisphenol Abisphenol A inhibits the reaction [IL1A protein promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to CCL2 promoter]]10614622
C006780bisphenol Abisphenol A inhibits the reaction [IL1A protein results in increased expression of CCL2 mRNA]10614622
C006780bisphenol Abisphenol A inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]10614622
C006780bisphenol Afulvestrant inhibits the reaction [bisphenol A inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]10614622
C006780bisphenol Abisphenol A results in increased expression of IL1A mRNA28500084
C006780bisphenol Abisphenol A results in increased expression of IL1A protein28500084
C006780bisphenol A[Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA24781736
C006780bisphenol Abisphenol A affects the expression of IL1A mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of IL1A gene28505145
D001761BleomycinIL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]8317554
D001761BleomycinIL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]8317554
D001761BleomycinIL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]8317554
D001761BleomycinBleomycin results in increased expression of IL1A protein29175452
C072125BRL 44408BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]]16192389
C016274bromoacetatebromoacetate results in decreased expression of IL1A mRNA19753638
C016274bromoacetatebromoacetate results in increased expression of IL1A mRNA19753638
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]11230753
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL1A mRNA22079614
D019328Buthionine SulfoximineLY6G protein affects the reaction [[zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA]29154782
D019328Buthionine Sulfoximine[zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA29154782
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]18691550
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]18691550
D002084Butylated HydroxytolueneButylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]8435107
C018475butyraldehydebutyraldehyde results in increased expression of IL1A mRNA26079696
D002104CadmiumCadmium results in increased expression of and results in increased secretion of IL1A protein18082304
D002104CadmiumCadmium results in increased expression of IL1A mRNA24828341
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1A protein]26138014
D019256Cadmium ChlorideCadmium Chloride results in increased expression of IL1A protein26138014
D019256Cadmium ChlorideCadmium Chloride results in increased expression of IL1A mRNA25528414|7536360
D019256Cadmium ChlorideCadmium Chloride results in increased secretion of IL1A protein7536360
D019256Cadmium Chloride"lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [Cadmium Chloride results in increased expression of IL1A mRNA]"7536360
D019256Cadmium Chloride"lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [Cadmium Chloride results in increased secretion of IL1A protein]"7536360
D019256Cadmium ChlorideCadmium Chloride results in increased expression of IL1A mRNA25446329
D019256Cadmium ChlorideCadmium Chloride results in increased secretion of IL1A protein7536360
D019256Cadmium Chloride"lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [Cadmium Chloride results in increased secretion of IL1A protein]"7536360
C058667cadmium selenide[cadmium selenide co-treated with zinc sulfide] results in increased expression of IL1A mRNA22342292
C037123cadmium sulfatecadmium sulfate results in increased expression of IL1A mRNA12064557|1467641
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL1A mRNA]16085347
D000001CalcimycinCalcimycin results in increased expression of IL1A mRNA8435107
C058076calpain inhibitor IIIcalpain inhibitor III affects the localization of IL1A protein24024155
C058819calphostin Ccalphostin C inhibits the reaction [IL1A protein results in increased secretion of IL6 protein]16532021
C459604candoxincandoxin results in decreased expression of IL1A mRNA16309724
D002211CapsaicinCapsaicin results in decreased expression of IL1A protein22150557
D002211Capsaicin[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]22150557
D002211CapsaicinNaproxen inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]22150557
D002211CapsaicinSumatriptan inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]22150557
C005563captaxcaptax results in increased expression of IL1A protein23178550
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of IL1A mRNA18395288
D002251Carbon TetrachlorideCD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IL1A mRNA]18395288
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased activity of IL1A protein25858767
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of IL1A protein17904177
D002259Carbonyl Cyanide p-TrifluoromethoxyphenylhydrazoneCarbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL1A mRNA16039398
D002351CarrageenanCarrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]12182845
D002351CarrageenanCarrageenan results in decreased expression of IL1A protein12182845
D002351CarrageenanDexamethasone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]12182845
D002351CarrageenanDexamethasone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]12182845
D002351CarrageenanMorphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]12182845
D002351CarrageenanNaloxone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]12182845
D002351CarrageenanNaloxone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]12182845
D002594CetylpyridiniumCetylpyridinium results in increased expression of IL1A protein25290854
D002713ChlorineChlorine results in decreased expression of IL1A mRNA22533443
C031294chlorobenzenechlorobenzene results in increased expression of IL1A protein23178550
D002726Chlorogenic AcidChlorogenic Acid results in decreased expression of IL1A mRNA20706672
C007020chlorophyllinchlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1A mRNA]19152381
C100187chloropicrinchloropicrin affects the expression of IL1A mRNA26352163
D002738ChloroquineChloroquine results in increased expression of IL1A15139008
D002746Chlorpromazine"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine"19362101
D002858Chromium AlloysChromium Alloys results in increased expression of IL1A protein21996445
D002858Chromium AlloysChromium Alloys results in increased secretion of IL1A protein21514653
D002858Chromium Alloys[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein12168658
D002858Chromium Alloys"lipopolysaccharide, E coli O55-B5 promotes the reaction [[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein]"12168658
C012843cinnamic aldehydecinnamic aldehyde results in increased expression of IL1A mRNA25290854
C012843cinnamic aldehydecinnamic aldehyde results in increased expression of IL1A mRNA28219650
D002939CiprofloxacinCiprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]16968468
D002939Ciprofloxacinwortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]16968468
C007076citralcitral results in increased expression of IL1A protein23178550
D017291Clarithromycin"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin"19362101
D017291Clarithromycin"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin"19362101
D017291Clarithromycin"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin"19362101
D002990ClobetasolClobetasol results in decreased secretion of IL1A protein15086553
D002994ClofibrateClofibrate inhibits the reaction [Oxazolone results in increased expression of IL1A protein]11851881
D002994ClofibrateClofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A protein]11851881
D002997Clomipramine"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clomipramine"19362101
D003000ClonidineBRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]]16192389
D003000ClonidineClonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]16192389
C000593591coagulin-Lcoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]27568862
C018021cobaltous chloridecobaltous chloride results in increased expression of IL1A protein23178550
D003042CocaineCocaine affects the expression of IL1A mRNA20187946
D003078ColchicineColchicine inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein]11154858
D003300Copper[Disulfiram binds to Copper] which results in increased expression of IL1A mRNA24690739
D003300CopperCopper results in increased secretion of IL1A protein19635393
D003300CopperCopper results in increased secretion of IL1A protein19635393
D003300Copper[Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of IL1A mRNA20302851
D003436Croton OilCroton Oil results in increased expression of IL1A mRNA8006454
D003436Croton OilCroton Oil results in increased expression of IL1A protein8006454
D003436Croton OilIL1A protein affects the reaction [Croton Oil results in increased expression of CXCL8 protein]8006454
D003436Croton Oil"lipopolysaccharide, E coli O55-B5 inhibits the reaction [Croton Oil results in increased expression of IL1A protein]"8006454
D003436Croton OilCroton Oil results in increased expression of IL1A mRNA19647056
C029892cupric chloridecupric chloride results in increased secretion of IL1A protein22954531
C029892cupric chlorideIL1A protein binds to cupric chloride22699969
C029892cupric chloridecupric chloride results in increased expression of IL1A mRNA19616320
C029892cupric chloridecupric chloride results in increased expression of IL1A protein19616320
C030973cupric oxidecupric oxide results in increased expression of and results in increased secretion of IL1A protein22954531
D003474CurcuminCurcumin inhibits the reaction [IL1A protein results in increased expression of TNFSF11 protein]18719352
D003474CurcuminCurcumin inhibits the reaction [Soot results in increased secretion of IL1A protein]19782127
C038459curdlancurdlan affects the expression of IL1A mRNA19904525
C038459curdlancurdlan results in increased expression of IL1A mRNA23543010
C038459curdlancurdlan results in increased expression of IL1A protein19904525
C114438cyanidin 3-O-glucosidecyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]27818126
C114438cyanidin 3-O-glucoside[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein27818126
C114438cyanidin 3-O-glucoside[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA27818126
C114438cyanidin 3-O-glucoside[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA27818126
C114438cyanidin 3-O-glucoside[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein27818126
C114438cyanidin 3-O-glucosideMesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein]27818126
D003513CycloheximideCycloheximide results in increased expression of IL1A mRNA19684285
D003513Cycloheximide[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1A mRNA19684285
D003520CyclophosphamideIL1A promoter polymorphism affects the susceptibility to Cyclophosphamide16636934
D003520CyclophosphamideCyclophosphamide results in increased expression of IL1A mRNA15331540
D003520CyclophosphamideCyclophosphamide results in increased expression of IL1A protein18848347
D016572CyclosporineCyclosporine results in decreased expression of IL1A protein25051504
D003609DactinomycinDactinomycin inhibits the reaction [IL1A protein results in increased expression of FOS mRNA]7564102
C004742daidzeindaidzein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA]11473722
D003671DEET[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein28659758
D003671DEET[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNA28659758
D003676DeferoxamineDeferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]21703343
D013759DronabinolDronabinol results in increased expression of IL1A mRNA16039398
D003707Demeclocycline"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Demeclocycline"19362101
C007262deoxynivalenoldeoxynivalenol results in increased expression of IL1A mRNA15371230|1568116
C007262deoxynivalenol"Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL1A mRNA]"15681167
C007262deoxynivalenolLipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]16009389
C007262deoxynivalenol[deoxynivalenol co-treated with fumonisin B1] results in decreased expression of IL1A mRNA23688591
C007262deoxynivalenol[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C007262deoxynivalenol[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C007262deoxynivalenol[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA23688591
C007262deoxynivalenol[deoxynivalenol co-treated with nivalenol] results in increased expression of IL1A mRNA23688591
C007262deoxynivalenol[deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C007262deoxynivalenol[deoxynivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA23688591
C007262deoxynivalenol[deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA23688591
C007262deoxynivalenoldeoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1A mRNA]27915442
C007262deoxynivalenoldeoxynivalenol results in decreased expression of IL1A mRNA23688591
C007262deoxynivalenoldeoxynivalenol results in increased expression of IL1A mRNA23326479|2368859
C007262deoxynivalenoldeoxynivalenol results in increased expression of IL1A protein23326479
C007262deoxynivalenolnivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]27915442
D003907Dexamethasone"2-(6-((3-(4-(diphenylmethoxy)piperidino)propyl)amino)imidazo(1,2-b)pyridazin-2-yl)-2-methylpropionic acid inhibits the reaction [Dexamethasone results in increased expression of IL1A mRNA]"12438553
D003907DexamethasoneDexamethasone inhibits the reaction [IL1A protein results in increased expression of PTGS1 mRNA]15167967
D003907DexamethasoneDexamethasone inhibits the reaction [IL1A protein results in increased expression of PTGS1 protein]15167967
D003907DexamethasoneDexamethasone inhibits the reaction [IL1A protein results in increased expression of PTGS2 mRNA]15167967
D003907DexamethasoneDexamethasone inhibits the reaction [IL1A protein results in increased expression of PTGS2 protein]15167967
D003907DexamethasoneDexamethasone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]12182845
D003907DexamethasoneDexamethasone inhibits the reaction [IL1A protein promotes the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]]7540993
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]16880258|2218540
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]27568862
D003907DexamethasoneDexamethasone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]12182845
D003907DexamethasoneDexamethasone results in decreased expression of IL1A mRNA22185406
D003907DexamethasoneDUSP1 gene mutant form inhibits the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]]16880258
D016264Dextran SulfateDextran Sulfate results in increased expression of IL1A mRNA23894361|2547295
D016264Dextran Sulfatenotoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1A mRNA]25472953
D003958DiamideDiamide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
D003958DiamideDiamide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]7476933
C492519diarylpropionitrilediarylpropionitrile inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]21127968
D002945CisplatinCisplatin results in increased expression of IL1A mRNA26546572
D002945CisplatinCisplatin results in increased expression of IL1A protein20844023
D004008Diclofenac"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Diclofenac"19362101
C121718dicyclanildicyclanil results in increased expression of IL1A mRNA15664270
D004041Dietary FatsDietary Fats results in decreased expression of IL1A mRNA25016146
D004041Dietary Fats[fexofenadine co-treated with Dietary Fats co-treated with APOE gene mutant form] results in decreased expression of IL1A protein25020133
C034281diethylaminediethylamine results in increased activity of IL1A protein15840424
C014476diethyl maleatediethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
C014476diethyl maleatediethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]7476933
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]18691550
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]18691550
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of IL1A protein18691550
D004052DiethylnitrosamineIKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]18691550
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of IL1A mRNA18544905
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of IL1A protein25051504
D004052Diethylnitrosamine[Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of IL1A mRNA20302851
D004052Diethylnitrosamine[Iron co-treated with Diethylnitrosamine] results in increased expression of IL1A mRNA20302851
D004052Diethylnitrosamine[isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA21295105
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of IL1A mRNA15171707
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of IL1A protein15794588
D000875AnthralinAnthralin results in increased expression of IL1A mRNA7665919|8435107
D000875AnthralinAnthralin results in increased expression of IL1A protein7665919
D000875AnthralinPlant Extracts inhibits the reaction [Anthralin results in increased expression of IL1A mRNA]7665919
D000875AnthralinPlant Extracts inhibits the reaction [Anthralin results in increased expression of IL1A protein]7665919
D002117CalcitriolCalcitriol results in decreased expression of IL1A protein2525134
C472511dimethylarsinous aciddimethylarsinous acid results in decreased expression of IL1A mRNA19945496
D004128DimethylnitrosamineCSF3 protein affects the reaction [Dimethylnitrosamine affects the expression of IL1A mRNA]17869372
D004128DimethylnitrosamineDimethylnitrosamine affects the expression of IL1A mRNA17869372
D004121Dimethyl SulfoxideDimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]21878375
C547156dimethylthioarsinic aciddimethylthioarsinic acid results in decreased expression of IL1A mRNA19945496
D004137DinitrochlorobenzeneDinitrochlorobenzene affects the secretion of IL1A protein12781210
D004137DinitrochlorobenzeneDinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
D004137DinitrochlorobenzeneDinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]7476933
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of IL1A mRNA12781210
D004137DinitrochlorobenzeneDinitrochlorobenzene affects the expression of IL1A mRNA28219650
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased activity of IL1A protein15840424
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of IL1A mRNA18652873
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of IL1A protein18652873|2317855
D004139DinitrofluorobenzeneDinitrofluorobenzene affects the secretion of IL1A protein12781210
D004139DinitrofluorobenzeneDinitrofluorobenzene results in increased expression of IL1A mRNA12781210
D004139DinitrofluorobenzeneDinitrofluorobenzene results in increased expression of IL1A protein8006454
D004221Disulfiram[Disulfiram binds to Copper] which results in increased expression of IL1A mRNA24690739
D004229Dithiothreitol[Dithiothreitol co-treated with IL1A protein] results in increased expression of SOD2 protein7476933
D004229DithiothreitolDithiothreitol promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
D004317DoxorubicinIL1A protein promotes the reaction [Doxorubicin results in increased expression of CAT protein]8317554
D004317DoxorubicinIL1A protein promotes the reaction [Doxorubicin results in increased expression of SOD1 protein]8317554
D004317DoxorubicinIL1A protein promotes the reaction [Doxorubicin results in increased expression of SOD2 protein]8317554
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Estrogens results in increased expression of IL1A]"14758024
D004391DustDust affects the expression of IL1A protein17805423
C509867E804 bisindoleE804 bisindole inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]23107598
C509867E804 bisindoleE804 bisindole results in increased expression of IL1A mRNA23107598
C509867E804 bisindoleLipopolysaccharides inhibits the reaction [E804 bisindole results in increased expression of IL1A mRNA]23107598
D0151175,8,11,14-Eicosatetraynoic Acid"5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]"8435107
C007590emulphogene BC 720emulphogene BC 720 results in increased expression of IL1A mRNA25398874
D004656EnalaprilEnalapril inhibits the reaction [IL1A protein results in increased expression of VEGFA mRNA]17299153
D004656EnalaprilEnalapril inhibits the reaction [IL1A protein results in increased expression of VEGFA protein]17299153
D004731EndotoxinsEndotoxins results in increased expression of IL1A mRNA12217210
C031818enterotoxin B, staphylococcal"enterotoxin B, staphylococcal results in increased expression of and results in increased secretion of IL1A protein"25556216
C118739entinostatentinostat results in increased expression of IL1A mRNA27188386
C062669epicatechin gallateepicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]7665919
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of IL1A mRNA20706672
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IL1A mRNA22079256
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]7665919
D000069347Erlotinib Hydrochloride[Erlotinib Hydrochloride results in decreased susceptibility to Erlotinib Hydrochloride] which results in increased expression of IL1A mRNA27738319
D004917ErythromycinErythromycin results in increased expression of IL1A mRNA27503388
D004917Erythromycin[Penicillin G co-treated with Erythromycin] results in increased expression of IL1A mRNA27503388
D004964EstriolEstriol results in decreased expression of IL1A mRNA10731640
D004967Estrogens"Drugs, Chinese Herbal inhibits the reaction [Estrogens results in increased expression of IL1A]"14758024
C017296estrone sulfateestrone sulfate results in decreased expression of IL1A mRNA10731640
D000431Ethanolacanthoic acid inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of IL1A mRNA]28964808
D000431Ethanol[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of IL1A mRNA28964808
D000431EthanolEthanol results in decreased expression of IL1A mRNA28964808
D000431EthanolEthanol results in increased expression of IL1A protein28843478
D004996EthidiumEthidium inhibits the reaction [sodium arsenate results in increased expression of IL1A protein]10571731
D004996EthidiumEthidium inhibits the reaction [tributyltin results in increased expression of IL1A protein]8875956
D004997Ethinyl Estradiol[Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of IL1A mRNA24781736
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of IL1A protein25051504
D005000EthionamideEthionamide results in increased expression of IL1A protein25051504
C004919ethylene dimethacrylateethylene dimethacrylate results in increased expression of IL1A protein23178550
D005033EthylmaleimideEthylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
D005033EthylmaleimideEthylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]7476933
D015025Zearalenone[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
D015025Zearalenone[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA23688591
D015025Zearalenone[deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
D015025Zearalenone[deoxynivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA23688591
D015025Zearalenone[deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA23688591
D015025Zearalenone[nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
D015025Zearalenone[nivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA23688591
D015025Zearalenone[nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA23688591
D015025Zearalenone[Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
D015025ZearalenoneZearalenone results in increased expression of IL1A mRNA23688591
C093230fexofenadine[fexofenadine co-treated with Dietary Fats co-treated with APOE gene mutant form] results in decreased expression of IL1A protein25020133
D005436FloxacillinFloxacillin results in increased secretion of IL1A protein28444390
D005439Flufenamic AcidFlufenamic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]10866999
D005446Fluocinolone AcetonideFluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]8435107
D005492Folic Acid[Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of IL1A mRNA22975265
D005492Folic Acid[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of IL1A mRNA24657277
D005557FormaldehydeFormaldehyde results in increased expression of and results in increased secretion of IL1A protein18082304
D037741FullerenesFullerenes analog results in increased expression of IL1A mRNA22342292
C070081fulvestrantfulvestrant inhibits the reaction [bisphenol A inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]10614622
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]10614622
C070081fulvestrantfulvestrant inhibits the reaction [nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]10614622
C056933fumonisin B1[deoxynivalenol co-treated with fumonisin B1] results in decreased expression of IL1A mRNA23688591
C056933fumonisin B1[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C056933fumonisin B1[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C056933fumonisin B1[deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C056933fumonisin B1fumonisin B1 results in decreased expression of IL1A mRNA23688591
C056933fumonisin B1fumonisin B1 results in increased expression of IL1A mRNA23688591
C056933fumonisin B1[nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C056933fumonisin B1[nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C056933fumonisin B1[Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C039281furanfuran results in decreased expression of IL1A mRNA20194422
C064925gadodiamidegadodiamide results in increased expression of IL1A protein20938346
C038958gadolinium chloridegadolinium chloride inhibits the reaction [Lindane results in increased expression of IL1A mRNA]15025948
C038958gadolinium chloridegadolinium chloride inhibits the reaction [Lindane results in increased expression of IL1A protein]15025948
C056507gemcitabinegemcitabine results in decreased expression of IL1A protein20531411
D019833GenisteinGenistein results in decreased expression of IL1A mRNA20706672
D019833GenisteinGenistein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA]11473722
D005839GentamicinsGentamicins results in decreased expression of IL1A protein25051504
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]15728660
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]15728660
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]15705589
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]17109745
D005944GlucosamineGlucosamine results in increased expression of IL1A mRNA17109745
D005944GlucosamineIL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA]17109745
D006017Glycolipids[Glycolipids analog co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA16374148
C081021Go 6976Go 6976 inhibits the reaction [IL1A protein results in increased secretion of IL6 protein]16532021
D006046Gold[Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein22155353
D006046GoldGold results in increased secretion of IL1A protein22155353
D006118GriseofulvinGriseofulvin inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein]11367519
C018562guggulu extract"guggulu extract inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of IL1A mRNA]"22940226
D006418HemeHeme metabolite results in increased expression of IL1A mRNA19191707
D006538Heptanoic AcidsHeptanoic Acids results in increased secretion of IL1A protein23999410
C013015hesperetinhesperetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]24707119
C080043hexyl cinnamic aldehydehexyl cinnamic aldehyde results in increased expression of IL1A protein23178550
D017313FenretinideFenretinide results in decreased expression of IL1A mRNA16467112
D006854HydrocortisoneHydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein]18722610
D006854HydrocortisoneHydrocortisone inhibits the reaction [IL1A protein results in increased expression of MMP9 mRNA]18722610
D006854HydrocortisoneHydrocortisone results in decreased expression of IL1A mRNA21980503
D006854HydrocortisoneMifepristone inhibits the reaction [Hydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein]]18722610
D006854HydrocortisoneNR3C1 protein promotes the reaction [Hydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein]]18722610
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of IL1A mRNA26339600
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of IL1A mRNA11378323
C031927hydroquinonehydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]1868253
C031927hydroquinonehydroquinone results in decreased cleavage of IL1A protein8548860|9118901
D007052IbuprofenIbuprofen inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]11230753
D007052IbuprofenIbuprofen results in increased expression of IL1A mRNA17070997
C081281ibuprofen acyl glucuronideibuprofen acyl glucuronide results in increased expression of IL1A mRNA26528891
C490483icilinicilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein]23596210
C006048imidazolidinyl ureaimidazolidinyl urea results in increased expression of IL1A protein23178550
D007213IndomethacinIndomethacin inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]11230753
D007213IndomethacinIndomethacin inhibits the reaction [Benzene inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]]1868253
D007213IndomethacinIndomethacin results in increased expression of IL1A protein25051504
D053590Interleukin 1 Receptor Antagonist ProteinInterleukin 1 Receptor Antagonist Protein results in decreased secretion of IL1A protein27738319
D007501Iron[Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of IL1A mRNA20302851
D007501Iron[Iron co-treated with Diethylnitrosamine] results in increased expression of IL1A mRNA20302851
C036643isoeugenolisoeugenol results in increased expression of IL1A protein23178550
D007538IsoniazidIsoniazid results in increased secretion of IL1A protein28444390
D007545IsoproterenolIsoproterenol results in decreased expression of IL1A mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of IL1A mRNA24286936
D007545IsoproterenolIsoproterenol results in decreased expression of IL1A mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of IL1A mRNA24286936
C016527isoquercitrin[isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA21295105
D007559Ivermectin[Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein16861626
C098607JP8 aviation fuelJP8 aviation fuel affects the expression of IL1A mRNA17085751
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of IL1A protein11509030|1739501
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of IL1A mRNA24796395|2596192
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of IL1A mRNA24231268
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [[KRAS mutant form co-treated with TRP53 mutant form] results in increased expression of IL1A protein]26390243
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]25890327|2658214
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]26582142
C037057Kathon 886Kathon 886 results in increased expression of IL1A protein23178550
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of IL1A mRNA18544905
D019344Lactic AcidLactic Acid results in increased secretion of IL1A protein23999410
D019344Lactic AcidLactic Acid results in increased expression of IL1A protein23178550
C017461lead nitrate[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA]22293356
C017461lead nitrate[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]22293356
C017461lead nitrate[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of HMGCR mRNA]22293356
C017461lead nitrate[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of TNF mRNA]22293356
C017461lead nitrate[IL1A gene mutant form co-treated with IL1B gene mutant form] results in decreased susceptibility to lead nitrate22293356
C017461lead nitratelead nitrate results in increased expression of IL1A mRNA22293356
C467567lenalidomidelenalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of IL1A mRNA]16510725
C032854leupeptinleupeptin inhibits the reaction [Particulate Matter results in increased secretion of IL1A protein]21818627
D001556Lindanealpha-Tocopherol inhibits the reaction [Lindane results in increased expression of IL1A mRNA]15025948
D001556Lindanealpha-Tocopherol inhibits the reaction [Lindane results in increased expression of IL1A protein]15025948
D001556Lindanegadolinium chloride inhibits the reaction [Lindane results in increased expression of IL1A mRNA]15025948
D001556Lindanegadolinium chloride inhibits the reaction [Lindane results in increased expression of IL1A protein]15025948
D001556LindaneLindane results in increased expression of IL1A mRNA15025948
D001556LindaneLindane results in increased expression of IL1A protein15025948
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1A mRNA"23090859
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 inhibits the reaction [Croton Oil results in increased expression of IL1A protein]"8006454
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of IL1A mRNA"21865417
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of IL1A protein"21865417
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 promotes the reaction [[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein]"12168658
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of IL1A protein"23604539
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1A protein"21724870
C482199lipopolysaccharide, E coli O55-B5"neocuproine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1A protein]"23604539
C482199lipopolysaccharide, E coli O55-B5"tetrathiomolybdate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1A protein]"21724870
C482199lipopolysaccharide, E coli O55-B5"[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of IL1A mRNA"20371263
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nimesulide"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Azathioprine"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clomipramine"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Demeclocycline"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Diclofenac"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Mexiletine"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Nortriptyline"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Quinine"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Riluzole"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Tretinoin"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[lipopolysaccharide, Escherichia coli O111 B4 co-treated with roridin A] affects the expression of IL1A mRNA"17483119
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [Cadmium Chloride results in increased expression of IL1A mRNA]"7536360
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [Cadmium Chloride results in increased secretion of IL1A protein]"7536360
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1A mRNA"17483119|7536360
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1A protein"7536360
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Ranitidine"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to telithromycin"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin"19362101
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [Cadmium Chloride results in increased secretion of IL1A protein]"7536360
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1A protein"7536360
D008070Lipopolysaccharides15-deoxyprostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]10866999
D008070Lipopolysaccharidesacanthoic acid inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of IL1A mRNA]28964808
D008070Lipopolysaccharides[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of IL1A mRNA28964808
D008070LipopolysaccharidesFlufenamic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]10866999
D008070Lipopolysaccharideshesperetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]24707119
D008070LipopolysaccharidesHNRNPD protein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]21135123
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1A mRNA15779068
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1A protein15779068
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of IL1A mRNA21878375
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A mRNA9122163
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of IL1A mRNA28964808
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL1A mRNA15860229|1792931
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL1A protein10866999|2470711
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of IL1A protein20005085
D008070Lipopolysaccharides[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL1A protein18437699
D008070LipopolysaccharidesPhloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]24707119
D008070LipopolysaccharidesQuercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]17929310
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]17929310
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]24707119
D008070LipopolysaccharidesSilver promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]26968431
D008070LipopolysaccharidesSilymarin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]24707119
D008070Lipopolysaccharides[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of IL1A mRNA22777745
D008070Lipopolysaccharides4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]16880258
D008070LipopolysaccharidesAdenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]26068648
D008070LipopolysaccharidesBenzene inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]1868253
D008070Lipopolysaccharidescoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]27568862
D008070LipopolysaccharidesDexamethasone inhibits the reaction [IL1A protein promotes the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]]7540993
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]16880258|2218540
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]27568862
D008070LipopolysaccharidesDUSP1 gene mutant form inhibits the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]]16880258
D008070LipopolysaccharidesE804 bisindole inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]23107598
D008070Lipopolysaccharideshydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]1868253
D008070LipopolysaccharidesIL1A protein promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]7540993
D008070LipopolysaccharidesIL6 protein affects the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]15804595
D008070LipopolysaccharidesIndomethacin inhibits the reaction [Benzene inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]]1868253
D008070Lipopolysaccharides(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]25890327|2658214
D008070Lipopolysaccharides(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]26582142
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein26068648
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [E804 bisindole results in increased expression of IL1A mRNA]23107598
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]16009389
D008070LipopolysaccharidesLipopolysaccharides results in increased cleavage of IL1A protein1868253
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL1A mRNA15371095|1600256
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL1A protein1868253|19133137
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of IL1A protein26582142
D008070LipopolysaccharidesMelatonin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]21461237
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]15933225
D008070Lipopolysaccharides"(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]]"26068648
D008070Lipopolysaccharides"(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein]"26068648
D008070Lipopolysaccharidesphenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]20423518
D008070LipopolysaccharidesQuercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]22185406
D008070Lipopolysaccharides[RORA protein affects the susceptibility to Lipopolysaccharides] which affects the expression of IL1A28698385
D008070Lipopolysaccharidesterameprocol affects the reaction [Lipopolysaccharides results in increased expression of IL1A protein]19133137
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL1A mRNA25613284
D008070Lipopolysaccharides"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]"21127968
D008070Lipopolysaccharides"[Asbestos, Crocidolite co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA"9400719
D008070Lipopolysaccharides"[Asbestos, Serpentine co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA"9400719
D008070Lipopolysaccharidesdiarylpropionitrile inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]21127968
D008070LipopolysaccharidesEstradiol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein]21127968
D008070Lipopolysaccharides[Glycolipids analog co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA16374148
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [Zymosan results in increased expression of IL1A protein]16192389
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL1A protein21362633
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of IL1A protein21127968|2150475
D008070Lipopolysaccharides[potassium octatitanate co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA9400719
D008070Lipopolysaccharides[RCF-1 fiber co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA9400719
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL1A mRNA28528741
D008070Lipopolysaccharidesochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]28528741
D008070LipopolysaccharidesTLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]]28528741
D008070Lipopolysaccharides[TNF protein co-treated with IL1B protein co-treated with IFNG protein co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA20816778
D019808LosartanLosartan inhibits the reaction [IL1A protein results in increased expression of VEGFA mRNA]17299153
D019808LosartanLosartan inhibits the reaction [IL1A protein results in increased expression of VEGFA protein]17299153
D019808LosartanLosartan results in decreased expression of IL1A protein23875703
C013592mangiferinmangiferin results in decreased expression of IL1A mRNA15135318
D008550MelatoninMelatonin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]21461237
D008550MelatoninMelatonin results in decreased expression of IL1A mRNA21461237
D008623Mercaptoethanol[Mercaptoethanol co-treated with IL1A protein] results in increased expression of SOD2 protein7476933
D008623MercaptoethanolMercaptoethanol promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
D008627Mercuric ChlorideMercuric Chloride results in increased expression of IL1A protein21984480
D008691MethadoneMethadone results in increased expression of IL1A protein20178837
D008694Methamphetamine[Methamphetamine co-treated with SCH 23390] results in increased expression of IL1A mRNA19564919
D008694MethamphetamineMethamphetamine results in increased expression of IL1A mRNA19564919
D008701MethapyrileneMethapyrilene results in increased expression of IL1A protein25051504
D008727Methotrexate[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of IL1A mRNA24657277
D008727MethotrexateMethotrexate results in decreased expression of IL1A mRNA17400583
D008727MethotrexateMethotrexate results in increased expression of IL1A mRNA17379860|1910030
C013598methoxyacetic acidmethoxyacetic acid results in increased expression of IL1A mRNA28238932
D008748MethylcholanthreneMethylcholanthrene results in increased expression of IL1A mRNA14993811
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]15933225
D020366MethylmethacrylateMethylmethacrylate results in increased expression of IL1A protein23178550
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]"25406165
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]"25406165
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA"25406165
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of IL1A mRNA"22940226
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"guggulu extract inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of IL1A mRNA]"22940226
C033069methyl salicylatemethyl salicylate results in increased expression of IL1A protein23178550
D008790MetoprololMetoprolol results in increased expression of IL1A mRNA17467819
D008790MetoprololMetoprolol results in increased secretion of IL1A protein17467819
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]15728660
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]15705589
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased localization of RELA protein]]15705589
D008801Mexiletine"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Mexiletine"19362101
C011309mezereinmezerein results in increased expression of IL1A mRNA7665919|8435107
C011309mezereinmezerein results in increased expression of IL1A protein7665919
C011309mezereinPlant Extracts inhibits the reaction [mezerein results in increased expression of IL1A mRNA]7665919
C011309mezereinPlant Extracts inhibits the reaction [mezerein results in increased expression of IL1A protein]7665919
D015735MifepristoneMifepristone inhibits the reaction [Hydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein]]18722610
D019016Mineral FibersMineral Fibers results in increased expression of IL1A protein16364376
C054999mofezolacmofezolac inhibits the reaction [IL1A protein results in increased abundance of Dinoprostone]15167967
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of IL1A mRNA16809437
D016686MonocrotalineMonocrotaline results in decreased expression of IL1A protein25051504
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of IL1A mRNA22108045
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of IL1A mRNA20886546
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of IL1A protein20045430
D009020MorphineCarrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]12182845
D009020MorphineDexamethasone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]12182845
D009020MorphineDexamethasone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]12182845
D009020MorphineMorphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]12182845
D009020MorphineMorphine results in decreased expression of IL1A protein12182845
D009020MorphineNaloxone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]12182845
D009020MorphineNaloxone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]12182845
D009151Mustard GasMustard Gas results in increased expression of IL1A protein8603935
D009151Mustard GasMustard Gas results in increased expression of IL1A protein11428647
D009151Mustard GasMustard Gas affects the expression of IL1A mRNA15651846
D009151Mustard GasMustard Gas results in increased expression of IL1A protein18852015
D009173Mycophenolic AcidMycophenolic Acid results in increased expression of IL1A mRNA26394380
C515928(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide)"(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]]"26068648
C515928(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide)"(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein]"26068648
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]11230753
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased abundance of Dinoprostone]15167967
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]11230753
C058346N-(4-methoxyphenyl)retinamideN-(4-methoxyphenyl)retinamide results in decreased expression of IL1A mRNA16467112
C086501N-acetylcysteine lysinateN-acetylcysteine lysinate inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]15613243
D009270NaloxoneNaloxone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]12182845
D009270NaloxoneNaloxone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]12182845
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of IL1A mRNA"20800606
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of IL1A mRNA"25102311
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of IL1A mRNA"24389112
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of IL1A mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of IL1A"25510677
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of IL1A mRNA"25554681
D009288Naproxen[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]22150557
D009288NaproxenNaproxen inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]22150557
C007548n-dodecanen-dodecane results in increased expression of and results in increased secretion of IL1A protein19720135
D000068577NebivololNebivolol results in decreased expression of IL1A mRNA17467819
C051752nefazodone"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone"19362101
C051752nefazodone"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone"19362101
C002701neocuproine"neocuproine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1A protein]"23604539
C015380neoechinulinneoechinulin results in decreased expression of IL1A mRNA19818335
C490266neoechinulin Aneoechinulin A results in decreased expression of IL1A mRNA19818335
C007932n-hexadecanen-hexadecane results in increased expression of and results in increased secretion of IL1A protein19720135
D009532NickelNickel results in increased expression of IL1A mRNA23195993
C022838nickel chloride[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL1A protein18437699
C022838nickel chloridenickel chloride results in increased expression of IL1A mRNA11378323|1731216
C022838nickel chloridenickel chloride results in decreased expression of IL1A protein23178550
C029938nickel sulfateIL1A protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein]15679580
C029938nickel sulfateIL1A protein affects the reaction [nickel sulfate results in increased secretion of CXCL8 protein]15679580
C029938nickel sulfatenickel sulfate results in increased secretion of IL1A protein15679580
D009538NicotineNicotine results in increased expression of and results in increased secretion of IL1A protein18082304
C012655nimesulide"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nimesulide"19362101
D009569Nitric OxideCiprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]16968468
D009569Nitric Oxide[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide16968468
D009569Nitric Oxidewortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]16968468
D009569Nitric Oxidegeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
D009569Nitric OxideIL1A results in increased abundance of Nitric Oxide15705589
D009569Nitric OxideMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
D009569Nitric OxideSimvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]15705589
D009569Nitric OxideY 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
D009569Nitric Oxide[IL1A protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide10205228
D009569Nitric OxideIL1A protein results in increased chemical synthesis of Nitric Oxide10205228
D009569Nitric Oxidetroglitazone promotes the reaction [[IL1A protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]10205228
D009569Nitric Oxidetroglitazone promotes the reaction [IL1A protein results in increased chemical synthesis of Nitric Oxide]10205228
C038405nivalenol[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C038405nivalenol[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C038405nivalenol[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA23688591
C038405nivalenol[deoxynivalenol co-treated with nivalenol] results in increased expression of IL1A mRNA23688591
C038405nivalenoldeoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1A mRNA]27915442
C038405nivalenol[nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C038405nivalenol[nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA23688591
C038405nivalenol[nivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA23688591
C038405nivalenol[nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA23688591
C038405nivalenolnivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]27915442
C038405nivalenolnivalenol results in decreased expression of IL1A mRNA23688591
C038405nivalenolnivalenol results in increased expression of IL1A mRNA23688591|2791544
C017573nonanenonane results in increased expression of IL1A protein15451557
C010615Nonidet P-40Nonidet P-40 results in decreased expression of IL1A mRNA26552463
D017137NonoxynolNonoxynol results in increased secretion of IL1A protein20937349
C025256nonylphenolfulvestrant inhibits the reaction [nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]10614622
C025256nonylphenolnonylphenol inhibits the reaction [IL1A protein promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to CCL2 promoter]]10614622
C025256nonylphenolnonylphenol inhibits the reaction [IL1A protein results in increased expression of CCL2 mRNA]10614622
C025256nonylphenolnonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]10614622
D009661Nortriptyline"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Nortriptyline"19362101
C072936notoginsenoside R1notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1A mRNA]25472953
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1A protein]"18509044
C024713n-tetradecanen-tetradecane results in increased expression of and results in increased secretion of IL1A protein19720135
C025589ochratoxin Aochratoxin A results in increased expression of IL1A mRNA26394380
C025589ochratoxin Aochratoxin A results in increased expression of IL1A mRNA28286205
C025589ochratoxin Aochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]28528741
C025589ochratoxin ATLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]]28528741
D017830OctoxynolOctoxynol results in increased secretion of IL1A protein23999410
C474055octylphenoloctylphenol results in increased expression of IL1A mRNA24781736
C474055octylphenol[Streptozocin co-treated with octylphenol] results in increased expression of IL1A mRNA24781736
D015525Fatty Acids, Omega-3"Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL1A mRNA]"15681167
C485800osajinosajin results in decreased expression of IL1A mRNA20706672
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of IL1A mRNA25729387
D010081OxazoloneOxazolone affects the secretion of IL1A protein12781210
D010081OxazoloneOxazolone results in increased expression of IL1A mRNA12781210
D010081OxazoloneClofibrate inhibits the reaction [Oxazolone results in increased expression of IL1A protein]11851881
D010081OxazoloneOxazolone results in increased expression of IL1A protein11851881|1865287
D010100OxygenOxygen deficiency inhibits the reaction [TNF protein results in increased expression of IL1A protein]8702551
D010100OxygenOxygen deficiency results in decreased expression of IL1A protein8702551
D010100OxygenOxygen deficiency results in decreased stability of and results in decreased expression of IL1A mRNA8702551
D010100OxygenOxygen promotes the reaction [TNF protein results in increased expression of IL1A protein]24024155
D010100OxygenOxygen results in increased expression of IL1A mRNA24024155
D010100OxygenOxygen results in increased expression of IL1A protein24024155
D010100OxygenSOD2 protein promotes the reaction [Oxygen deficiency inhibits the reaction [TNF protein results in increased expression of IL1A protein]]8702551
D010100OxygenSOD2 protein promotes the reaction [Oxygen deficiency results in decreased expression of IL1A protein]8702551
D010126Ozone[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of IL1A protein27472835
D010126OzoneOzone results in increased expression of IL1A mRNA17575079
D010126OzoneOzone results in increased expression of IL1A mRNA12377989|2862317
D010126OzoneTNF protein promotes the reaction [Ozone results in increased expression of IL1A mRNA]12377989
D010126OzoneOzone results in increased expression of IL1A protein10593593
D010269ParaquatIL1A protein promotes the reaction [Paraquat results in increased expression of CAT protein]8317554
D010269ParaquatIL1A protein promotes the reaction [Paraquat results in increased expression of SOD1 protein]8317554
D010269ParaquatIL1A protein promotes the reaction [Paraquat results in increased expression of SOD2 protein]8317554
D010269ParaquatParaquat results in increased expression of IL1A mRNA20883675
D010269ParaquatParaquat results in increased expression of IL1A mRNA22938100
C084656paricalcitol[Phosphorus co-treated with paricalcitol] results in increased expression of IL1A mRNA17715259
C002669parthenolideparthenolide results in decreased expression of IL1A mRNA16921510
D052638Particulate Matter"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]"15613243
D052638Particulate Matter2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]20464547
D052638Particulate Matter4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]20464547
D052638Particulate Matter"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]"15613243
D052638Particulate MatterCAT protein inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]21703343
D052638Particulate MatterDeferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]21703343
D052638Particulate Matterleupeptin inhibits the reaction [Particulate Matter results in increased secretion of IL1A protein]21818627
D052638Particulate MatterN-acetylcysteine lysinate inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]15613243
D052638Particulate MatterParticulate Matter results in decreased expression of IL1A mRNA24927667
D052638Particulate MatterParticulate Matter results in increased expression of and results in increased secretion of IL1A protein26507108
D052638Particulate MatterParticulate Matter results in increased expression of IL1A mRNA15613243|2046454
D052638Particulate MatterParticulate Matter results in increased secretion of IL1A protein21818627|2834120
D052638Particulate MatterPolymyxin B inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]21703343
D052638Particulate MatterVerapamil inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]15613243
D052638Particulate MatterW 7 inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]15613243
D052638Particulate MatterParticulate Matter results in increased expression of IL1A21724521
D052638Particulate MatterParticulate Matter results in increased expression of IL1A mRNA21708214|2718798
D052638Particulate MatterParticulate Matter results in increased expression of IL1A protein27865893
D052638Particulate MatterParticulate Matter results in increased secretion of IL1A protein23962744
D052638Particulate Matter[IL1A protein co-treated with IL1B protein] promotes the reaction [Particulate Matter results in increased secretion of IL6 protein]18700232
D052638Particulate MatterParticulate Matter results in increased expression of IL1A21724521
C410127PCB 180PCB 180 affects the expression of IL1A mRNA21703328
C008776pelargonic acidpelargonic acid results in increased expression of IL1A mRNA18652873
D000068437Pemetrexed[Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of IL1A mRNA22975265
D010400Penicillin G[Penicillin G co-treated with Erythromycin] results in increased expression of IL1A mRNA27503388
D010400Penicillin GPenicillin G results in increased expression of IL1A mRNA27503388
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of IL1A mRNA27294297
D010457PeptidoglycanPeptidoglycan results in increased expression of IL1A mRNA15860229
C522391perfluorododecanoic acidperfluorododecanoic acid results in decreased expression of IL1A mRNA19397962
D026023Permethrin[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein28659758
D026023Permethrin[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNA28659758
D015232DinoprostoneIL1A protein results in increased abundance of Dinoprostone15167967|2151376
D015232Dinoprostonemofezolac inhibits the reaction [IL1A protein results in increased abundance of Dinoprostone]15167967
D015232DinoprostoneN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased abundance of Dinoprostone]15167967
D015232Dinoprostone[IL1A protein co-treated with Arachidonic Acid] results in increased abundance of Dinoprostone11351503
D015232DinoprostoneIL1A protein results in increased abundance of Dinoprostone8218930
D015232DinoprostoneIL1A protein results in increased secretion of Dinoprostone16169897
C058305phenethyl isothiocyanatephenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]20423518
D010634PhenobarbitalPhenobarbital results in decreased expression of IL1A mRNA19162173
D010634PhenobarbitalPhenobarbital results in increased expression of IL1A protein25051504
D019800PhenolIL1A protein affects the reaction [Phenol results in increased expression of CXCL8 protein]8006454
D019800PhenolPhenol results in increased expression of IL1A mRNA8006454
D019800PhenolPhenol results in increased expression of IL1A protein8006454
D019800PhenolPhenol results in increased secretion of IL1A protein16522979
D010693PhloretinPhloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]24707119
D010713PhosphatidylcholinesIL1A results in increased hydrolysis of Phosphatidylcholines15756928
D010758Phosphorus[Phosphorus co-treated with paricalcitol] results in increased expression of IL1A mRNA17715259
C043103phthalic anhydridephthalic anhydride results in increased activity of IL1A protein15840424
C117268pimecrolimuspimecrolimus results in increased secretion of IL1A protein15086553
C006253pirinixic acidpirinixic acid results in decreased expression of IL1A protein20131406
D010936Plant ExtractsIL1A gene SNP affects the reaction [Plant Extracts results in decreased expression of CRP protein]17884346
D010936Plant ExtractsIL1A gene SNP affects the reaction [Plant Extracts results in decreased expression of IL1B protein]17884346
D010936Plant ExtractsPlant Extracts results in decreased expression of IL1A mRNA24927667
D010936Plant ExtractsPlant Extracts inhibits the reaction [Anthralin results in increased expression of IL1A mRNA]7665919
D010936Plant ExtractsPlant Extracts inhibits the reaction [Anthralin results in increased expression of IL1A protein]7665919
D010936Plant ExtractsPlant Extracts inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A mRNA]7665919
D010936Plant ExtractsPlant Extracts inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A protein]7665919
D010936Plant ExtractsPlant Extracts inhibits the reaction [mezerein results in increased expression of IL1A mRNA]7665919
D010936Plant ExtractsPlant Extracts inhibits the reaction [mezerein results in increased expression of IL1A protein]7665919
D010936Plant ExtractsPlant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]7665919
D010972Platelet Activating FactorPlatelet Activating Factor results in increased expression of IL1A mRNA16386258
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls affects the expression of IL1A mRNA21334430
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased expression of IL1A mRNA16002475
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased expression of IL1A mRNA16002475
C107145poly(hexamethylenebiguanidinium)poly(hexamethylenebiguanidinium) results in increased expression of IL1A protein25111876
C107145poly(hexamethylenebiguanidinium)poly(hexamethylenebiguanidinium) results in increased expression of IL1A protein25111876
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of IL1A protein29175452
D011112Polymyxin BPolymyxin B inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]21703343
D011137PolystyrenesPolystyrenes analog results in increased expression of IL1A mRNA25102311
D011137PolystyrenesPolystyrenes results in increased expression of IL1A mRNA25102311
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IL1A mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of IL1A mRNA22079256
D011192Potassium DichromatePotassium Dichromate results in increased expression of IL1A mRNA20619327
D011192Potassium DichromatePotassium Dichromate results in increased secretion of IL1A protein20619327
C021028potassium octatitanate[potassium octatitanate co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA9400719
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of IL1A mRNA19162173
D011339Probenecid"1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]"25406165
D011339Probenecid"1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]"25406165
D011339Probenecid"[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA"25406165
D011374ProgesteroneProgesterone results in increased expression of IL1A mRNA20631399
D0198402-Propanol2-Propanol results in decreased expression of IL1A protein23178550
D011429PropolisPropolis results in decreased expression of IL1A mRNA20706672
D015237DinoprostIL1A protein results in increased abundance of Dinoprost21513769
D011464EpoprostenolIL1A protein results in increased abundance of Epoprostenol21513769
D011509ProteoglycansIL1A protein inhibits the reaction [IGF1 protein results in increased metabolism of Proteoglycans]16646036
C033607puerarinpuerarin results in decreased expression of IL1A mRNA20706672
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of CXCL10 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of CXCL8 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of FGF2 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of GCH1 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of ICAM1 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of IL1A mRNA]12832416|1283241
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of IL1B mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of IL6 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of MMP1 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of MMP3 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of PTGS2 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of PTX3 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of SERPINB2 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased phosphorylation of JUN protein]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased secretion of CXCL8 protein]12832416
C432165pyrazolanthronepyrazolanthrone promotes the reaction [IL1A protein results in increased expression of BIRC2 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone promotes the reaction [IL1A protein results in increased expression of CCL8 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone promotes the reaction [IL1A protein results in increased expression of CXCL3 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone promotes the reaction [IL1A protein results in increased expression of JUN mRNA]12832416
C432165pyrazolanthronepyrazolanthrone promotes the reaction [IL1A protein results in increased expression of SAA1 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Soot results in increased secretion of IL1A protein]19782127
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein28659758
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNA28659758
D011794QuercetinQuercetin inhibits the reaction [IL1A protein results in increased expression of PRKCQ protein modified form]16532021
D011794QuercetinQuercetin inhibits the reaction [IL1A protein results in increased secretion of IL6 protein]16532021
D011794QuercetinQuercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]17929310
D011794QuercetinQuercetin results in decreased expression of IL1A mRNA23727915
D011794QuercetinQuercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]22185406
D011794QuercetinQuercetin results in decreased expression of IL1A mRNA22185406
D011796QuinacrineQuinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]8435107
D011803Quinine"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Quinine"19362101
D011899Ranitidine"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Ranitidine"19362101
C103119RCF-1 fiber[RCF-1 fiber co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA9400719
C059514resveratrol[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with resveratrol] results in increased activity of NFE2L2 protein27818126
C059514resveratrol[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with resveratrol] results in increased expression of GCLC mRNA27818126
C059514resveratrol[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with resveratrol] results in increased expression of HMOX1 mRNA27818126
C059514resveratrolMesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with resveratrol] results in increased expression of HMOX1 mRNA]27818126
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]17929310
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]24707119
C059514resveratrolresveratrol promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]27818126
C059514resveratrolresveratrol results in decreased expression of IL1A mRNA20706672|2293340
C059514resveratrolresveratrol analog results in decreased expression of IL1A mRNA15652768
D015474IsotretinoinIsotretinoin results in decreased secretion of IL1A protein15972972
D019782Riluzole"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Riluzole"19362101
C116926rofecoxibrofecoxib affects the expression of IL1A mRNA17070997
C038849roridin A"[lipopolysaccharide, Escherichia coli O111 B4 co-treated with roridin A] affects the expression of IL1A mRNA"17483119
C038849roridin Aroridin A results in increased expression of IL1A mRNA17483119
D012402RotenoneRotenone inhibits the reaction [sodium arsenate results in increased expression of IL1A protein]10571731
D012402RotenoneRotenone inhibits the reaction [tributyltin results in increased expression of IL1A protein]8875956
D020156Salicylic AcidSalicylic Acid results in increased expression of IL1A protein23178550
C093642SB 203580SB 203580 inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]15728660
C093642SB 203580SB 203580 inhibits the reaction [IL1A protein results in increased secretion of IL6 protein]16532021
C093642SB 203580SB 203580 inhibits the reaction [IL1A results in increased expression of PTGS2 mRNA]14742690
C093642SB 203580SB 203580 inhibits the reaction [IL1A results in increased expression of PTGS2 protein]14742690
C534628SCH 23390[Methamphetamine co-treated with SCH 23390] results in increased expression of IL1A mRNA19564919
C534628SCH 23390SCH 23390 results in increased expression of IL1A mRNA19564919
D012601Scopolamine HydrobromideIL1A protein results in decreased susceptibility to Scopolamine Hydrobromide8003924
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of IL1A mRNA"24160326
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of IL1A protein"17200189
D017632Asbestos, Serpentine"[Asbestos, Serpentine co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA"9400719
D012715Sesame OilSesame Oil results in increased secretion of IL1A protein23999410
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of IL1A mRNA23806026
D012822Silicon DioxideSilicon Dioxide results in increased expression of IL1A mRNA19428942|2230053
D012822Silicon Dioxide[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein12168658
D012822Silicon Dioxide[Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein22155353
D012822Silicon Dioxide"lipopolysaccharide, E coli O55-B5 promotes the reaction [[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein]"12168658
D012834SilverSilver affects the expression of IL1A mRNA22342292
D012834SilverSilver promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]26968431
D012834SilverSilver results in increased expression of IL1A mRNA26968431
D012838SilymarinSilymarin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]24707119
D012838SilymarinSilymarin inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A protein]10753220
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]15728660
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]15728660
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]15728660
D019821SimvastatinSimvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]15728660
D019821SimvastatinSimvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]15728660
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]15705589
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]15705589
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased localization of RELA protein]]15705589
D019821SimvastatinSimvastatin inhibits the reaction [IL1A results in decreased expression of NFKBIA protein modified form]15705589
D019821SimvastatinSimvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]15705589
D019821SimvastatinSimvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]15705589
D019821SimvastatinSimvastatin inhibits the reaction [IL1A results in increased expression of NOS2 mRNA]15705589
D019821SimvastatinSimvastatin inhibits the reaction [IL1A results in increased localization of RELA protein]15705589
D019821SimvastatinY 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]15705589
D019821SimvastatinY 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
C009277sodium arsenateEthidium inhibits the reaction [sodium arsenate results in increased expression of IL1A protein]10571731
C009277sodium arsenateRotenone inhibits the reaction [sodium arsenate results in increased expression of IL1A protein]10571731
C009277sodium arsenatesodium arsenate results in increased expression of IL1A protein10571731
C017947sodium arsenite"2,2'-Dipyridyl inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]"24570342
C017947sodium arsenite3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]24570342
C017947sodium arseniteAcetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]24570342
C017947sodium arseniteLCN2 mutant form inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]24570342
C017947sodium arsenitesodium arsenite results in decreased expression of IL1A mRNA12679051
C017947sodium arsenitesodium arsenite results in increased expression of IL1A mRNA20886546|2457034
C017947sodium arsenitesodium arsenite results in decreased expression of IL1A mRNA21911445
C016104sodium bichromatesodium bichromate results in increased expression of IL1A protein22011396
D012965Sodium ChlorideSodium Chloride results in increased expression of IL1A mRNA11378323
D012967Sodium Dodecyl SulfateIL1A protein affects the reaction [Sodium Dodecyl Sulfate results in increased secretion of CCL20 protein]15679580
D012967Sodium Dodecyl SulfateIL1A protein affects the reaction [Sodium Dodecyl Sulfate results in increased secretion of CXCL8 protein]15679580
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in increased expression of IL1A mRNA11378323|1278121
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in increased expression of IL1A protein25290854
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in increased secretion of IL1A protein12781210|1567958
D053260SootSoot results in increased expression of IL1A mRNA24982919
D053260Soot2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Soot results in increased secretion of IL1A protein]19782127
D053260Soot4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Soot results in increased secretion of IL1A protein]19782127
D053260SootCurcumin inhibits the reaction [Soot results in increased secretion of IL1A protein]19782127
D053260Sootpyrazolanthrone inhibits the reaction [Soot results in increased secretion of IL1A protein]19782127
D053260SootSoot results in increased secretion of IL1A protein19782127
D013205Staphylococcal Protein AStaphylococcal Protein A results in increased expression of IL1A protein15384034
D013311Streptozocin[Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA24781736
D013311Streptozocin[Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of IL1A mRNA24781736
D013311Streptozocin[Streptozocin co-treated with octylphenol] results in increased expression of IL1A mRNA24781736
D012460SulfasalazineSulfasalazine inhibits the reaction [[IL1A protein co-treated with OSM protein] results in increased expression of ADAMTS4 mRNA]19690126
D012460SulfasalazineSulfasalazine inhibits the reaction [[IL1A protein co-treated with OSM protein] results in increased expression of MMP13 mRNA]19690126
D012460SulfasalazineSulfasalazine inhibits the reaction [[IL1A protein co-treated with OSM protein] results in increased expression of MMP13 protein]19690126
D012460SulfasalazineSulfasalazine inhibits the reaction [[IL1A protein co-treated with OSM protein] results in increased expression of MMP1 mRNA]19690126
D012460SulfasalazineSulfasalazine inhibits the reaction [[IL1A protein co-treated with OSM protein] results in increased expression of MMP1 protein]19690126
D013467Sulindac"[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of IL1A mRNA"20371263
D018170Sumatriptan[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]22150557
D018170SumatriptanSumatriptan inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]22150557
D013605T-2 ToxinT-2 Toxin results in increased expression of IL1A mRNA21112371
C106791telithromycin"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to telithromycin"19362101
C076852terameprocolterameprocol affects the reaction [Lipopolysaccharides results in increased expression of IL1A protein]19133137
D013739TestosteroneTestosterone affects the expression of IL1A protein20403060
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1A mRNA19684285
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IL1A mRNA16039398
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of IL1A mRNA19684285|2315218
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of IL1A mRNA24713691|2756255
D013755Tetradecanoylphorbol Acetate[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A mRNA9122163
D013755Tetradecanoylphorbol AcetateSOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]21045076
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA]8702551
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of IL1A mRNA21045076|8702551
D013755Tetradecanoylphorbol Acetate"5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]"8435107
D013755Tetradecanoylphorbol AcetateButylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]8435107
D013755Tetradecanoylphorbol AcetateClofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A protein]11851881
D013755Tetradecanoylphorbol Acetateepicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]7665919
D013755Tetradecanoylphorbol Acetateepigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]7665919
D013755Tetradecanoylphorbol AcetateFluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]8435107
D013755Tetradecanoylphorbol AcetatePlant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]7665919
D013755Tetradecanoylphorbol AcetateQuinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]8435107
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of IL1A mRNA7665919|8435107
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of IL1A protein11851881
D013755Tetradecanoylphorbol AcetateTretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]8435107
C020809tetrathiomolybdate"tetrathiomolybdate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1A protein]"21724870
D013853ThioacetamideThioacetamide results in increased expression of IL1A protein25051504
D013883ThiostreptonThiostrepton results in decreased expression of IL1A mRNA22321511
C031462titanium alloy (TiAl6V4)[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein12168658
C031462titanium alloy (TiAl6V4)"lipopolysaccharide, E coli O55-B5 promotes the reaction [[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein]"12168658
C009495titanium dioxidetitanium dioxide affects the expression of IL1A mRNA19695317|2234229
C041500titanium nitride[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein12168658
C041500titanium nitride"lipopolysaccharide, E coli O55-B5 promotes the reaction [[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein]"12168658
C402696TMC 120ATMC 120A results in decreased expression of IL1A mRNA19818335
D014028Tobacco Smoke PollutionTobacco Smoke Pollution analog results in decreased expression of IL1A mRNA24927667
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of IL1A mRNA27404394|2786577
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of IL1A protein27480279
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of IL1A mRNA24096154
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of IL1A protein24096154
D014028Tobacco Smoke PollutionIL1A protein results in increased susceptibility to Tobacco Smoke Pollution22163019
D014028Tobacco Smoke PollutionTobacco Smoke Pollution deficiency inhibits the reaction [[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of IL1A protein]24096154
C082097tocotrienol, delta"tocotrienol, delta results in increased expression of IL1A mRNA"22185406
C056583tolmetin glucuronidetolmetin glucuronide results in increased expression of IL1A mRNA26528891
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased secretion of IL1A protein"1699434
D014051Toluene 2,4-Diisocyanate"IL1A protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of ICAM1 mRNA]"16210060
D014051Toluene 2,4-Diisocyanate"IL1A protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL4 mRNA]"16210060
D014051Toluene 2,4-Diisocyanate"IL1A protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of VCAM1 mRNA]"16210060
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of IL1A mRNA25729387
D019772TopotecanTopotecan results in increased expression of IL1A mRNA25729387
D017312ToremifeneToremifene inhibits the reaction [Estradiol results in increased expression of IL1A mRNA]12079510
D017312ToremifeneToremifene inhibits the reaction [Estradiol results in increased expression of IL1A protein]12079510
D014107Tosyllysine Chloromethyl KetoneTosyllysine Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
D014107Tosyllysine Chloromethyl KetoneTosyllysine Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]7476933
D014108Tosylphenylalanyl Chloromethyl KetoneTosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]7476933
D014108Tosylphenylalanyl Chloromethyl KetoneTosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]7476933
D014212Tretinoin"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Tretinoin"19362101
D014212TretinoinTretinoin inhibits the reaction [IL1A protein results in increased expression of IVL mRNA]17214633
D014212TretinoinTretinoin inhibits the reaction [IL1A protein results in increased expression of S100A8 mRNA]17214633
D014212TretinoinTretinoin inhibits the reaction [IL1A protein results in increased expression of S100A9 mRNA]17214633
D014212TretinoinTretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]8435107
D014212TretinoinTretinoin affects the activity of IL1A protein16847438
C011559tributyltin"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [tributyltin results in increased expression of IL1A protein]"9221826
C011559tributyltinEthidium inhibits the reaction [tributyltin results in increased expression of IL1A protein]8875956
C011559tributyltinRotenone inhibits the reaction [tributyltin results in increased expression of IL1A protein]8875956
C011559tributyltintributyltin results in increased expression of IL1A protein8875956|9221826
D014241TrichloroethyleneTrichloroethylene results in increased methylation of IL1A gene27618143
C012589trichostatin Atrichostatin A results in decreased expression of IL1A mRNA24935251
C012589trichostatin Atrichostatin A results in increased expression of IL1A mRNA24935251
D014260TriclosanTriclosan results in decreased expression of IL1A protein26048654
C094074tridecanetridecane results in increased expression of and results in increased secretion of IL1A protein19720135
C046488trimethyltintrimethyltin results in increased expression of IL1A mRNA20833246|2143539
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of IL1A mRNA12781210
D014302Trinitrobenzenesulfonic Acidicilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein]23596210
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of IL1A protein23596210
C025541tri-o-cresyl phosphateLY6G protein affects the reaction [[zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA]29154782
C025541tri-o-cresyl phosphate[zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA29154782
C057693troglitazonetroglitazone results in decreased expression of IL1A mRNA19631733
C057693troglitazonetroglitazone promotes the reaction [[IL1A protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]10205228
C057693troglitazonetroglitazone promotes the reaction [IL1A protein results in increased chemical synthesis of Nitric Oxide]10205228
C057693troglitazonetroglitazone promotes the reaction [IL1A protein results in increased expression of NOS2 mRNA]10205228
C080163trovafloxacin"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin"19362101
C080163trovafloxacin"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin"19362101
C080163trovafloxacin"[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin"19362101
D017973Tungsten CompoundsTungsten Compounds results in increased expression of IL1A mRNA28666766
D014520UrethaneUrethane results in increased expression of and results in increased secretion of IL1A protein18082304
C073339usnic acid[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of IL1A mRNA22777745
C066668vadimezanvadimezan results in increased expression of IL1A protein16944150
D014635Valproic AcidValproic Acid affects the expression of IL1A mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of IL1A mRNA28001369
D014635Valproic AcidValproic Acid affects the expression of IL1A mRNA17292431
D014639VanadiumVanadium results in increased expression of IL1A mRNA15159208
C034028vanadyl sulfatevanadyl sulfate results in increased expression of IL1A mRNA16330358
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL1A mRNA24982919
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of IL1A mRNA22906174
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL1A protein27865893
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL1A20478040
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL1A19914270
D014700VerapamilVerapamil inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]15613243
C025643vinclozolinvinclozolin results in increased expression of IL1A mRNA18629315
D024483Vitamin K 3"[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3"19362101
D024483Vitamin K 3Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of IL1A mRNA]19265712
D024483Vitamin K 3Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of IL1A protein]19265712
D024483Vitamin K 3Vitamin K 3 results in increased expression of IL1A mRNA19265712
D024483Vitamin K 3Vitamin K 3 results in increased secretion of IL1A protein19265712
C111237vorinostatvorinostat results in increased expression of IL1A mRNA18769122
C017967W 7W 7 inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA]15613243
C009687wortmanninwortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]16968468
D014992XylenesXylenes results in increased expression of IL1A protein23178550
C108830Y 27632Y 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]15705589
C108830Y 27632Y 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]15705589
D015215ZidovudineZidovudine results in increased expression of IL1A protein7979221
D015032ZincIL1A protein affects the metabolism of Zinc2458983
D015032ZincIL1A protein results in increased abundance of Zinc9278552
D015032ZincIL1A protein results in increased uptake of Zinc1502195
D015032ZincZinc promotes the reaction [IL1A protein results in increased expression of MT2A mRNA]1502195
D015032Zinc[IL1A protein co-treated with Zinc deficiency] results in increased expression of NOS2 protein9278552
D015032ZincIL1A protein inhibits the reaction [Zinc deficiency results in decreased expression of MT1A mRNA]9278552|9649590
D015032ZincIL1A protein promotes the reaction [Zinc deficiency results in increased expression of GUCA2B protein]12514266
D015032ZincIL1A protein promotes the reaction [Zinc deficiency results in increased expression of NOS2 mRNA]9278552
D015032Zinc[Zinc deficiency co-treated with IL1A protein] results in increased expression of GUCA2B mRNA12514266
D015032Zinc[Zinc deficiency co-treated with IL1A protein] results in increased expression of NOS2 mRNA12514266
D015032ZincZinc deficiency inhibits the reaction [IL1A protein results in increased expression of MT1A mRNA]12514266
D015032ZincZinc results in increased expression of IL1A mRNA15159208
C016837zinc chlorideNCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]18509044
C016837zinc chloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1A protein]"18509044
C016837zinc chloridePARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]18509044
C016837zinc chloridezinc chloride results in increased expression of IL1A protein18509044
D019287Zinc SulfateIL1A protein promotes the reaction [Zinc Sulfate results in increased expression of MT1G mRNA]22722935
D019287Zinc SulfateZinc Sulfate inhibits the reaction [TNF protein results in increased expression of IL1A mRNA]22722935
D019287Zinc SulfateZinc Sulfate promotes the reaction [IL1A protein results in increased expression of CXCL8 mRNA]22722935
D019287Zinc SulfateZinc Sulfate results in decreased expression of IL1A mRNA22722935
C031238zinc sulfide[cadmium selenide co-treated with zinc sulfide] results in increased expression of IL1A mRNA22342292
C020549zomepiraczomepirac metabolite results in increased expression of IL1A29154782
C020549zomepiracLY6G protein affects the reaction [[zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA]29154782
C020549zomepirac[zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA29154782
C027368zomepirac glucuronidezomepirac glucuronide results in increased expression of IL1A mRNA26528891
D015054ZymosanZymosan results in increased expression of IL1A mRNA14507659
D015054ZymosanBRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]]16192389
D015054ZymosanClonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]16192389
D015054ZymosanLipopolysaccharides promotes the reaction [Zymosan results in increased expression of IL1A protein]16192389
D015054ZymosanZymosan results in increased expression of IL1A protein16192389

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005125cytokine activity-IMP2989698  
GO:0005507copper ion binding-IDA12746488  
GO:0005515protein binding-IPI12746488  16971486  18329368  25241761  25416956  25910212  
GO ID GO Term Qualifier Evidence PubMed
GO:0001660fever generation-IEA-  
GO:0002248connective tissue replacement involved in inflammatory response wound healing-IEA-  
GO:0006915apoptotic process-TAS1924307  
GO:0006954inflammatory response-TAS6209582  
GO:0006955immune response-IEA-  
GO:0008283cell proliferation-TAS6209582  
GO:0008285negative regulation of cell proliferation-IDA3493774  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0010575positive regulation of vascular endothelial growth factor production-ISS-  
GO:0010628positive regulation of gene expression-IDA23817958  
GO:0019221cytokine-mediated signaling pathway-IMP2989698  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0032755positive regulation of interleukin-6 production-IEA-  
GO:0034605cellular response to heat-IDA12746488  
GO:0035234ectopic germ cell programmed cell death-IEA-  
GO:0045086positive regulation of interleukin-2 biosynthetic process-IMP2989698  
GO:0045766positive regulation of angiogenesis-ISS-  
GO:0045840positive regulation of mitotic nuclear division-IMP2989698  
GO:0045944positive regulation of transcription by RNA polymerase II-IEA-  
GO:0046688response to copper ion-IDA12746488  
GO:0050714positive regulation of protein secretion-IMP9564845  
GO:0050715positive regulation of cytokine secretion-IDA1739124  
GO:0051781positive regulation of cell division-IEA-  
GO:0070498interleukin-1-mediated signaling pathway-TAS-  
GO:0071639positive regulation of monocyte chemotactic protein-1 production-IEA-  
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand-IEA-  
GO:2000391positive regulation of neutrophil extravasation-IEA-  
GO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-TAS10748004  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IDA12746488  
GO:0005615extracellular space-IMP3493774  
GO:0005829cytosol-IDA12746488  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa04210Apoptosis
hsa04380Osteoclast differentiation
hsa04640Hematopoietic cell lineage
hsa04940Type I diabetes mellitus
hsa05020Prion diseases
hsa05140Leishmaniasis
hsa05323Rheumatoid arthritis
hsa05332Graft-versus-host disease
Reactome ID Reactome Term Evidence
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-168256Immune SystemTAS
R-HSA-2262752Cellular responses to stressTAS
R-HSA-2559582Senescence-Associated Secretory Phenotype (SASP)TAS
R-HSA-2559583Cellular SenescenceTAS
R-HSA-446652Interleukin-1 family signalingTAS
R-HSA-448706Interleukin-1 processingTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-6783783Interleukin-10 signalingTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-9020702Interleukin-1 signalingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23726808Interleukin 1B rs16944 G>A polymorphism was associated with a decreased risk of esophageal cancer in a Chinese population. (2013 Oct)Zheng LClin Biochem
24460370Relationship between IL1 gene polymorphisms and periodontal disease in Japanese women. (2014 Apr)Tanaka KDNA Cell Biol
21376376Genetic variations of interleukin-1 and -6 genes and risk of cervical intraepithelial neoplasia. (2011 Jun 1)Grimm CGynecol Oncol
23814583IL6 and IL10 are genetic susceptibility factors of periodontal disease. (2012 Dec)Scapoli LDent Res J (Isfahan)
19742166Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 variations does not impact alcohol dependence disorder features. (2009 Jul)Drago AInt J Environ Res Public Health
19505916Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women. (2009 Jun)Van Dyke ALCancer Epidemiol Biomarkers Prev
29744169Inflammatory mediator polymorphisms associate with initial periodontitis in adolescents. (2016 Dec)Heikkinen AMClin Exp Dent Res
15372320Interleukin 3 (IL3) polymorphisms associated with decreased risk of asthma and atopy. (2004)Park BLJ Hum Genet
15797878Interleukin-1 gene cluster polymorphisms and alcoholism in Spanish men. (2005 May-Jun)Pastor IJAlcohol Alcohol
24275344Role of familiarity versus interleukin-1 genes cluster polymorphisms in chronic periodontitis. (2014 Feb 10)Zuccarello DGene
11350506Failure to detect an association with IL1 genotypes in European Caucasians with generalised early onset periodontitis. (2001 May)Hodge PJJ Clin Periodontol
26722511Associations of interleukin-1 gene cluster polymorphisms with C-reactive protein concentration and lung function decline in smoking-induced chronic obstructive pulmonary disease. (2015)Wang YInt J Clin Exp Pathol
28915570IL1 genes polymorphism and the risk of renal cell carcinoma in Chinese Han population. (2017 Aug 22)Wang FOncotarget
15270852Environmental factors and not genotype influence the plasma level of interleukin-1 receptor antagonist in normal individuals. (2004 Aug)Cullup HClin Exp Immunol