Gene: FASLG

356
ALPS1B|APT1LG1|APTL|CD178|CD95-L|CD95L|FASL|TNFSF6|TNLG1A
Fas ligand
protein-coding
1q24.3
Ensembl:ENSG00000117560 MIM:134638 Vega:OTTHUMG00000034841 UniprotKB:P48023
NG_007269.1
PubMed
0   ANCO-SNPs
ND
4   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.401e-2 (AD)  9.365e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PARP150.793
SLAMF70.781
SLAMF60.768
TBX210.765
CD3G0.76
PYHIN10.756
GZMA0.755
LY90.753
FCRL30.74
FCRL50.738

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ADCY2-0.438
FUT9-0.424
CYP46A1-0.421
ZNF835-0.419
MYADML2-0.417
BDH1-0.416
TMEM221-0.413
DBP-0.408
HRH3-0.408
GREB1-0.406

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C55429110-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one"10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one inhibits the reaction [FAS protein binds to FASLG protein]"20833157
C50489712-(3-adamantan-1-ylureido)dodecanoic acid12-(3-adamantan-1-ylureido)dodecanoic acid affects the expression of FASLG mRNA19435785
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]"19720122
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]"15799720
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]"15799720
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Hydrogen Peroxide results in increased expression of FASLG protein]"15799720
C0389831,3-dimethylthiourea"1,3-dimethylthiourea inhibits the reaction [Cisplatin results in increased expression of FASLG mRNA]"12684229
C47781915-deoxyprostaglandin J215-deoxyprostaglandin J2 affects the expression of FASLG mRNA16912651
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of FASLG mRNA"25614096
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [evodiamine results in increased expression of FASLG protein]20005289
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of FASLG protein]21165570
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of FASLG protein"26451628
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Emodin results in increased expression of FASLG protein]27032576
C0081103,3'-iminodipropionitrile"3,3'-iminodipropionitrile results in increased expression of FASLG mRNA"22074697
C4824923,4,5,4'-tetramethoxystilbene"3,4,5,4'-tetramethoxystilbene results in increased expression of FASLG mRNA"22687606
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]"23452621
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]19720122
C0415944-nonylphenol4-nonylphenol results in increased expression of FASLG mRNA27087316|2710977
C0415944-nonylphenol4-nonylphenol results in increased expression of FASLG protein27087316|2710977
C0257249-methoxycamptothecin9-methoxycamptothecin results in increased expression of FASLG mRNA23369935
C496492abrineabrine results in increased expression of FASLG mRNA23788630
C496492abrineabrine results in increased expression of FASLG protein23788630
C496492abrineabrine promotes the reaction [FASLG protein binds to FAS protein]23788630
C496492abrineabrine results in increased expression of FASLG mRNA23788630
C496492abrineabrine results in increased expression of FASLG protein23788630
D000082AcetaminophenAcetaminophen results in increased expression of FASLG mRNA27761495
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]19720122
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Biological Products results in increased expression of FASLG protein]28219700
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]17574045
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]17574045
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]17574045
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]17574045
D000111Acetylcysteine[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of FASLG mRNA22429591
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Azoxymethane results in increased expression of FASLG protein]20431929
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Zinc results in increased expression of FASLG protein]11864783
D000111AcetylcysteineAcetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of FASLG protein]19760616
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA]19644561
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein]19644561
D000111AcetylcysteineAcetylcysteine results in increased expression of FASLG mRNA26332274
D000111Acetylcysteine[Atorvastatin Calcium co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]20946910
D017255AcitretinAcitretin results in increased expression of FASLG18624760
D000171AcroleinAcrolein results in increased expression of FASLG protein17320762
D000171AcroleinFASLG protein affects the reaction [Acrolein results in increased activity of CASP9 protein]17320762
D000171Acrolein[Acrolein co-treated with Zidovudine] results in increased expression of FASLG protein27238871
D000171AcroleinAcrolein promotes the reaction [RELA protein binds to FASLG promoter]27238871
D000171AcroleinAcrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]27238871
D000171AcroleinAcrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]27238871
D000171AcroleinAcrolein results in increased expression of FASLG mRNA27238871
D000171AcroleinHydralazine inhibits the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]27238871
D000171AcroleinHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]]27238871
D000171AcroleinHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]27238871
D000171AcroleinHydralazine inhibits the reaction [Acrolein results in increased expression of FASLG mRNA]27238871
D000171AcroleinHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]]27238871
D000171AcroleinHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]27238871
D000171AcroleinZidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]27238871
D000171AcroleinZidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]27238871
D000171AcroleinAcrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]27238871
D000171AcroleinAcrolein results in increased expression of FASLG mRNA27238871
D000171AcroleinHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]27238871
D000171AcroleinHydralazine inhibits the reaction [Acrolein results in increased expression of FASLG mRNA]27238871
D000171AcroleinHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]27238871
D000171AcroleinZidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]27238871
D020106AcrylamideAcrylamide results in increased expression of FASLG mRNA28959563
D000241AdenosineAdenosine results in increased expression of FASLG protein16419169
D000450AldosteroneAldosterone results in increased expression of FASLG protein19001025
C518327aloe emodinaloe emodin results in increased expression of FASLG protein19928967
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of FASLG mRNA28070108
D024502alpha-Tocopherolalpha-Tocopherol results in increased expression of FASLG mRNA26332274
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of FASLG mRNA21298039
C010845aluminum chloridealuminum chloride results in increased expression of FASLG mRNA23065425
D0150812-Naphthylamine2-Naphthylamine results in decreased expression of FASLG mRNA18247414
D000643Ammonium ChlorideAmmonium Chloride affects the expression of FASLG mRNA16483693
C030419andrographolide[andrographolide co-treated with Cisplatin] promotes the reaction [FAS protein binds to FASLG protein]24563380
C030419andrographolide[andrographolide co-treated with Cisplatin] results in increased expression of FASLG mRNA24563380
C030419andrographolide[andrographolide co-treated with Cisplatin] results in increased expression of FASLG protein24563380
C030419andrographolideandrographolide promotes the reaction [FAS protein binds to FASLG protein]24563380
C030419andrographolideandrographolide results in increased expression of FASLG mRNA24563380
C030419andrographolideandrographolide results in increased expression of FASLG protein24563380
D000735AndrostenedioneAndrostenedione results in decreased expression of FASLG mRNA21439382
D000806Angiotensin-Converting Enzyme InhibitorsAngiotensin-Converting Enzyme Inhibitors results in decreased expression of FASLG protein10971519
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of FASLG mRNA24449571
D016718Arachidonic Acid"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]"19720122
D016718Arachidonic Acid4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]19720122
D016718Arachidonic AcidAcetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]19720122
D016718Arachidonic AcidArachidonic Acid results in increased expression of FASLG mRNA19720122
D016718Arachidonic AcidArachidonic Acid results in increased expression of FASLG protein19720122
D016718Arachidonic AcidFOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]]19720122
D016718Arachidonic AcidJUN protein affects the reaction [Arachidonic Acid results in increased expression of FASLG protein]19720122
D016718Arachidonic AcidMAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]19720122
D001104ArbutinArbutin results in decreased expression of FASLG mRNA17103032
D001151Arsenic[Arsenic co-treated with Fluorides] results in decreased expression of FASLG mRNA19962721
D001151ArsenicArsenic results in decreased expression of FASLG mRNA11134558|1996272
D001151ArsenicArsenic results in increased expression of FASLG mRNA27838757
C006632arsenic trioxide[arsenic trioxide co-treated with Curcumin] results in increased expression of FASLG protein27430728
C006632arsenic trioxidearsenic trioxide promotes the reaction [puerarin results in increased expression of FASLG protein]20416161
C006632arsenic trioxidearsenic trioxide results in decreased expression of FASLG mRNA23911876
C006632arsenic trioxidearsenic trioxide results in increased expression of FASLG12975549
C006632arsenic trioxidearsenic trioxide results in increased expression of FASLG mRNA17530438
C006632arsenic trioxidearsenic trioxide results in increased expression of FASLG protein12684647|2743072
C006632arsenic trioxideBortezomib promotes the reaction [arsenic trioxide results in increased activity of FASLG]20471514
C006632arsenic trioxide[sanguinarine co-treated with arsenic trioxide] results in increased expression of FASLG mRNA24345465
D001194AsbestosAsbestos results in decreased expression of FASLG27042963
D017636Asbestos, Amphibole"Asbestos, Amphibole results in decreased expression of FASLG protein"20855422
D001241AspirinAspirin inhibits the reaction [Azoxymethane results in increased expression of FASLG mRNA]20043115
D001262AtenololAtenolol inhibits the reaction [Epinephrine results in increased expression of FASLG protein]10728402
D000069059Atorvastatin CalciumAtorvastatin Calcium inhibits the reaction [TNF protein results in decreased expression of and results in decreased secretion of FASLG protein modified form]15063428
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of FASLG protein modified form15063428
D000069059Atorvastatin Calcium[Atorvastatin Calcium co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]20946910
D001374AzacitidineAzacitidine results in increased susceptibility to FASLG protein18829727
D001374AzacitidineAzacitidine results in increased susceptibility to FASLG protein18829727
D001397AzoxymethaneAcetylcysteine inhibits the reaction [Azoxymethane results in increased expression of FASLG protein]20431929
D001397AzoxymethaneAzoxymethane results in increased expression of FASLG protein20431929
D001397AzoxymethaneAspirin inhibits the reaction [Azoxymethane results in increased expression of FASLG mRNA]20043115
D001397AzoxymethaneAzoxymethane results in increased expression of FASLG mRNA20043115
C040929bafilomycin A1bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]28378122
C580697BDMC-ABDMC-A results in increased expression of FASLG protein24365254
C044946benazeprilbenazepril inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]15315341
C044946benazeprilbenazepril promotes the reaction [Valsartan inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]]15315341
C044946benazeprilValsartan promotes the reaction [benazepril inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]]15315341
D019324beta-NaphthoflavoneAHR mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [FASLG protein binds to FASLG protein]]22951985
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased activity of [FASLG protein binds to FASLG protein]22951985
D001564Benzo(a)pyreneAHR mutant form inhibits the reaction [Benzo(a)pyrene promotes the reaction [FASLG protein results in increased cleavage of CASP8 protein]]22951985
D001564Benzo(a)pyreneAHR mutant form inhibits the reaction [Benzo(a)pyrene results in increased activity of [FASLG protein binds to FASLG protein]]22951985
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [FASLG protein results in increased cleavage of CASP8 protein]22951985
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of [FASLG protein binds to FASLG protein]22951985
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of FASLG mRNA18247414
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of FASLG protein16041517
D001564Benzo(a)pyreneNitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of FASLG protein]16041517
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]17574045
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]17574045
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]17574045
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [evodiamine results in increased expression of FASLG protein]20005289
D001599BerberineBerberine results in increased expression of FASLG mRNA20656010
D001599BerberineBerberine results in increased expression of FASLG protein20656010
D004958EstradiolEstradiol results in decreased expression of FASLG mRNA24349563
D004958EstradiolTamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA]20529085
D004958Estradiol[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA20529085
D004958Estradiol[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG protein20529085
D004958EstradiolEstradiol results in increased expression of and results in increased secretion of FASLG protein15545282
D004958EstradiolEstradiol results in increased expression of FASLG mRNA15545282
D004958EstradiolTamoxifen inhibits the reaction [Estradiol results in increased expression of FASLG protein]15545282
C023888beta-hexachlorocyclohexaneAcetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of FASLG protein]19760616
C023888beta-hexachlorocyclohexanebeta-hexachlorocyclohexane results in increased expression of FASLG protein19760616
D001629BezafibrateBezafibrate affects the expression of FASLG protein modified form15063428
D001688Biological ProductsAcetylcysteine inhibits the reaction [Biological Products results in increased expression of FASLG protein]28219700
D001688Biological ProductsBiological Products results in increased expression of FASLG protein28219700
C006780bisphenol Abisphenol A results in decreased expression of FASLG mRNA19267065|2518105
C006780bisphenol Abisphenol A results in increased expression of FASLG mRNA19267065|2355480
C006780bisphenol Abisphenol A results in increased expression of FASLG protein25461909
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of FASLG mRNA21601586
D001761BleomycinBleomycin results in increased expression of FASLG mRNA11350791
D000069286Bortezomib[Bortezomib co-treated with vorinostat] results in increased expression of FASLG mRNA17351739
D000069286Bortezomib[Bortezomib co-treated with vorinostat] results in increased expression of FASLG protein17351739
D000069286BortezomibBortezomib promotes the reaction [arsenic trioxide results in increased activity of FASLG]20471514
D000069286BortezomibBortezomib results in increased expression of FASLG protein17351739
D000069286BortezomibCurcumin inhibits the reaction [[vorinostat co-treated with Bortezomib] results in increased expression of FASLG protein]17351739
D0151248-Bromo Cyclic Adenosine Monophosphate[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FASLG protein16709600
C022777bufalinbufalin results in increased expression of FASLG protein27444971
C400541CA 074 methyl esterCA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of FASLG protein]28378122
D002101Cacodylic AcidCacodylic Acid results in increased expression of FASLG mRNA17481689
D019256Cadmium ChlorideCadmium Chloride results in increased expression of FASLG protein21819444
D019256Cadmium Chloridetelmisartan inhibits the reaction [Cadmium Chloride results in increased expression of FASLG protein]21819444
D000001CalcimycinCalcimycin affects the expression of FASLG protein25410152
C081643candesartancandesartan inhibits the reaction [Daunorubicin results in increased expression of FASLG protein]16324756
D002211CapsaicinCapsaicin results in increased expression of FASLG protein22150557
D002211Capsaicin[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FASLG protein]22150557
D002211CapsaicinNaproxen inhibits the reaction [Capsaicin results in increased expression of FASLG protein]22150557
D002211CapsaicinSumatriptan inhibits the reaction [Capsaicin results in increased expression of FASLG protein]22150557
D002217Carbachol[Carbachol results in increased activity of CHRM1 protein] which results in increased expression of FASLG mRNA8683117
D002217Carbachol[Carbachol results in increased activity of CHRM1 protein] which results in increased expression of FASLG protein8683117
D002246Carbon DisulfideCarbon Disulfide results in increased expression of FASLG mRNA17241545
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of FASLG mRNA16609999|1664405
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of FASLG protein17105443
D002251Carbon TetrachlorideIL10 protein promotes the reaction [Carbon Tetrachloride results in increased expression of FASLG mRNA]16609999|1710544
D002251Carbon TetrachlorideIL10 protein promotes the reaction [Carbon Tetrachloride results in increased expression of FASLG protein]17105443
D002258Carbonyl Cyanide m-Chlorophenyl HydrazoneCarbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of FASLG mRNA]24658017
C043211carvedilolcarvedilol results in decreased expression of FASLG12875697
C043211carvedilolcarvedilol inhibits the reaction [Epinephrine results in increased expression of FASLG protein]10728402
C054133casticincasticin results in increased expression of FASLG protein27862857
C034221catecholcatechol results in increased expression of FASLG protein23776099
C066624CDRI 85-287CDRI 85-287 results in increased expression of FASLG mRNA25655200
C066624CDRI 85-287ESR2 protein affects the reaction [CDRI 85-287 results in increased expression of FASLG mRNA]25655200
D000068579CelecoxibCelecoxib inhibits the reaction [Freund's Adjuvant results in increased expression of FASLG mRNA]24932515
D002518CeramidesSMPD1 protein affects the reaction [FASLG protein results in increased abundance of Ceramides]20061541
D002701ChloramphenicolChloramphenicol results in decreased expression of FASLG18559535
D002784CholesterolCholesterol analog results in increased expression of FASLG protein19477266
C043561chrysinchrysin inhibits the reaction [Freund's Adjuvant results in increased expression of FASLG mRNA]24932515
D015377CilastatinCilastatin inhibits the reaction [Cisplatin affects the localization of FASLG protein]20435919
C034211cinnabarcinnabar results in increased expression of FASLG protein25629042
D003024Clozapine[Clozapine analog co-treated with Hydrogen Peroxide] results in increased expression of FASLG mRNA16510162
D003024Clozapine[Clozapine co-treated with Hydrogen Peroxide co-treated with Tretinoin] results in increased expression of FASLG mRNA16510162
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP3 protein]16051694
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP8 protein]16051694
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [FASLG protein results in increased cleavage of CASP3 protein]16051694
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [FASLG protein results in increased cleavage of PARP1 protein]16051694
C018021cobaltous chloridecobaltous chloride results in decreased expression of FASLG mRNA17553155
C024989coenzyme Q10coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]27087047
D019327Copper SulfateCopper Sulfate results in increased expression of FASLG mRNA21765606
D019327Copper SulfateGW0742 inhibits the reaction [Copper Sulfate results in increased expression of FASLG mRNA]21765606
C029892cupric chloridecupric chloride results in decreased expression of FASLG mRNA24650576
D003474Curcumin[arsenic trioxide co-treated with Curcumin] results in increased expression of FASLG protein27430728
D003474CurcuminCurcumin inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]23452621
D003474CurcuminCurcumin inhibits the reaction [[vorinostat co-treated with Bortezomib] results in increased expression of FASLG protein]17351739
D003474CurcuminCurcumin results in decreased expression of FASLG mRNA16101141
D003474CurcuminCurcumin results in decreased expression of FASLG mRNA10925121
D003474CurcuminCurcumin results in decreased expression of FASLG18462866
D003513CycloheximideCycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FASLG mRNA]11007951
D003513Cycloheximide[Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A mRNA19833194
D003513Cycloheximide[Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A protein19833194
D003520Cyclophosphamide[Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FASLG16166447
D016572CyclosporineCyclosporine results in decreased expression of FASLG protein9247148
D016572CyclosporineCyclosporine results in decreased secretion of FASLG protein11692113
D016572CyclosporineCyclosporine inhibits the reaction [FASLG protein results in increased activity of CAPN1 protein]23283937
D016572CyclosporineCyclosporine inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]15799720
D016572CyclosporineCyclosporine inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]15799720
D016572CyclosporineCyclosporine results in increased expression of FASLG mRNA10617104
C004315danthrondanthron results in increased expression of FASLG protein21126053
D003630Daunorubicincandesartan inhibits the reaction [Daunorubicin results in increased expression of FASLG protein]16324756
D003630DaunorubicinDaunorubicin results in increased expression of FASLG protein16324756
D003907DexamethasoneDexamethasone results in decreased expression of FASLG protein9528991
D003907DexamethasoneDexamethasone results in decreased secretion of FASLG protein11692113
D003907DexamethasoneDexamethasone results in decreased expression of FASLG mRNA11778176
D003907DexamethasoneDexamethasone results in decreased expression of FASLG protein11778176
D003976DiazinonDiazinon results in decreased expression of FASLG mRNA27920530
D003976Diazinon[Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FASLG mRNA]27920530
D002945CisplatinAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]17574045
D002945CisplatinAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]17574045
D002945CisplatinAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]17574045
D002945CisplatinAcetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]17574045
D002945Cisplatin[andrographolide co-treated with Cisplatin] promotes the reaction [FAS protein binds to FASLG protein]24563380
D002945Cisplatin[andrographolide co-treated with Cisplatin] results in increased expression of FASLG mRNA24563380
D002945Cisplatin[andrographolide co-treated with Cisplatin] results in increased expression of FASLG protein24563380
D002945CisplatinBCL2 protein inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]17574045
D002945CisplatinBCL2 protein inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]17574045
D002945CisplatinBCL2 protein inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]17574045
D002945Cisplatinbenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]17574045
D002945Cisplatinbenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]17574045
D002945Cisplatinbenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]17574045
D002945Cisplatin[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein17574045
D002945Cisplatin[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein17574045
D002945Cisplatin[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein17574045
D002945Cisplatin[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein17574045
D002945Cisplatin[Cisplatin co-treated with fisetin] results in increased expression of FASLG protein21216935
D002945CisplatinCisplatin results in increased expression of FASLG mRNA16957513|2087807
D002945CisplatinCisplatin results in increased expression of FASLG protein16957513|2121693
D002945Cisplatin[nutlin 3 promotes the reaction [FAS protein binds to FASLG protein]] which results in increased susceptibility to Cisplatin21509038
D002945CisplatinY 27632 inhibits the reaction [Cisplatin results in increased expression of FASLG mRNA]20878077
D002945Cisplatin"1,3-dimethylthiourea inhibits the reaction [Cisplatin results in increased expression of FASLG mRNA]"12684229
D002945CisplatinCisplatin results in increased expression of FASLG mRNA12684229
D002945CisplatinCilastatin inhibits the reaction [Cisplatin affects the localization of FASLG protein]20435919
D002945CisplatinCisplatin affects the localization of FASLG protein20435919
D003633Dichlorodiphenyl DichloroethyleneAcetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA]19644561
D003633Dichlorodiphenyl DichloroethyleneAcetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein]19644561
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA16921742|1964456
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein19644561
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of FASLG protein12477725
D004054DiethylstilbestrolTestosterone inhibits the reaction [Diethylstilbestrol results in increased expression of FASLG protein]12477725
D002117CalcitriolCalcitriol results in decreased expression of FASLG protein17570329
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FASLG mRNA"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FASLG mRNA]"21294050
D004121Dimethyl SulfoxideDimethyl Sulfoxide results in decreased expression of FASLG mRNA10925121
C031291diphenyliodoniumdiphenyliodonium inhibits the reaction [CD40LG protein results in increased expression of FASLG protein]22295117
C521792DMU-212DMU-212 results in increased expression of FASLG mRNA22687606
D004281Docosahexaenoic Acids[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which affects the localization of FASLG protein16963249
D017292DoxazosinDoxazosin results in increased expression of FASLG mRNA12771931
D004317DoxorubicinANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]15763944
D004317DoxorubicinDoxorubicin results in increased expression of FASLG mRNA15763944|1708886
D004317Doxorubicin[FAS protein co-treated with FASLG protein] results in increased susceptibility to Doxorubicin15981920
D004317DoxorubicinLovastatin inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]17088865
D004317Doxorubicin[THBS1 protein alternative form co-treated with Doxorubicin] results in increased expression of FASLG protein15818399
D004317Doxorubicin"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]"15799720
D004317Doxorubicin"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]"15799720
D004317Doxorubicinbenazepril inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]15315341
D004317Doxorubicinbenazepril promotes the reaction [Valsartan inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]]15315341
D004317Doxorubicincoenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]27087047
D004317DoxorubicinCyclosporine inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]15799720
D004317DoxorubicinCyclosporine inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]15799720
D004317DoxorubicinDoxorubicin results in increased expression of and results in increased activity of FASLG protein24593989
D004317DoxorubicinDoxorubicin results in increased expression of FASLG mRNA15799720|2718193
D004317DoxorubicinDoxorubicin results in increased expression of FASLG protein15315341|1579972
D004317DoxorubicinDoxorubicin results in increased secretion of FASLG protein15703961
D004317DoxorubicinFungal Polysaccharides inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]27181935
D004317DoxorubicinPropolis inhibits the reaction [Doxorubicin results in increased expression of and results in increased activity of FASLG protein]24593989
D004317DoxorubicinValsartan inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]15315341
D004317DoxorubicinValsartan promotes the reaction [benazepril inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]]15315341
D004642Emodin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Emodin results in increased expression of FASLG protein]27032576
D004642EmodinEmodin results in increased expression of FASLG protein27032576
D004642EmodinSB 203580 promotes the reaction [Emodin results in increased expression of FASLG protein]27032576
D004642EmodinU 0126 promotes the reaction [Emodin results in increased expression of FASLG protein]27032576
D004656EnalaprilEnalapril results in decreased expression of FASLG mRNA10925121
D015251EpirubicinEpirubicin results in increased expression of FASLG protein19429229
D015251EpirubicinEpirubicin results in increased expression of FASLG protein modified form19429229
D004837EpinephrineAtenolol inhibits the reaction [Epinephrine results in increased expression of FASLG protein]10728402
D004837Epinephrinecarvedilol inhibits the reaction [Epinephrine results in increased expression of FASLG protein]10728402
D004837EpinephrineEpinephrine results in increased expression of FASLG protein10728402
C007628esculetin[esculetin co-treated with Paclitaxel] results in increased expression of FASLG protein16051289
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased expression of FASLG mRNA24316378
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased expression of FASLG protein24316378
C074283estradiol 3-benzoateQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of FASLG mRNA]24316378
C074283estradiol 3-benzoateQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of FASLG protein]24316378
D000431EthanolEthanol promotes the reaction [RELA protein binds to FASLG promoter]24899502
D000431EthanolEthanol promotes the reaction [SP1 protein binds to FASLG promoter]24899502
D005047EtoposideEtoposide results in increased activity of FASLG promoter10811113
D005047Etoposide[linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D005047EtoposideNitric Oxide inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D005047Etoposide[S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D005047Etoposide[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D005047Etoposide[spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
C049639evodiamine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [evodiamine results in increased expression of FASLG protein]20005289
C049639evodiaminebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [evodiamine results in increased expression of FASLG protein]20005289
C049639evodiamineevodiamine results in increased expression of FASLG protein20005289
C049639evodiaminewortmannin inhibits the reaction [evodiamine results in increased expression of FASLG protein]20005289
C017875fisetin[Cisplatin co-treated with fisetin] results in increased expression of FASLG protein21216935
C017875fisetinfisetin results in increased expression of FASLG protein21216935
C028610flavanoneflavanone results in increased expression of FASLG mRNA22056764
D005419FlavonoidsFlavonoids results in increased expression of FASLG mRNA18035473
D005459Fluorides[Arsenic co-treated with Fluorides] results in decreased expression of FASLG mRNA19962721
D005459FluoridesFluorides results in decreased expression of FASLG mRNA19962721
D005485FlutamideFlutamide inhibits the reaction [Testosterone results in increased expression of FASLG mRNA]24658017
D005485FlutamideFlutamide results in decreased expression of FASLG protein20850791
D005557FormaldehydeFormaldehyde results in increased expression of FASLG mRNA12679049
D005620Freund's AdjuvantCelecoxib inhibits the reaction [Freund's Adjuvant results in increased expression of FASLG mRNA]24932515
D005620Freund's Adjuvantchrysin inhibits the reaction [Freund's Adjuvant results in increased expression of FASLG mRNA]24932515
D005620Freund's AdjuvantFreund's Adjuvant results in increased expression of FASLG mRNA24932515
C070081fulvestrantfulvestrant results in decreased expression of FASLG mRNA20145137
C070081fulvestrant[fulvestrant results in increased expression of TGFB1 protein] which results in increased expression of FASLG mRNA20145137
D062610Fungal PolysaccharidesFungal Polysaccharides inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]27181935
C039281furanfuran results in increased expression of FASLG mRNA22079235
D005665FurosemideFurosemide affects the expression of FASLG mRNA17497460
D005707Gallic AcidGallic Acid results in increased expression of FASLG protein22245431
D019833GenisteinGenistein inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]23452621
D019833GenisteinGenistein results in increased expression of FASLG protein24299158
C004312glycidolglycidol results in increased expression of FASLG mRNA24915197
C479979GW0742GW0742 inhibits the reaction [Copper Sulfate results in increased expression of FASLG mRNA]21765606
D006581HexachlorobenzeneHexachlorobenzene results in increased expression of FASLG protein21787832
D006830HydralazineHydralazine inhibits the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]27238871
D006830HydralazineHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]]27238871
D006830HydralazineHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]27238871
D006830HydralazineHydralazine inhibits the reaction [Acrolein results in increased expression of FASLG mRNA]27238871
D006830HydralazineHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]]27238871
D006830HydralazineHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]27238871
D006830HydralazineHydralazine inhibits the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]27238871
D006830HydralazineHydralazine inhibits the reaction [Zidovudine results in increased expression of FASLG mRNA]27238871
D006830HydralazineHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]27238871
D006830HydralazineHydralazine inhibits the reaction [Acrolein results in increased expression of FASLG mRNA]27238871
D006830HydralazineHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]27238871
D006830HydralazineHydralazine inhibits the reaction [Zidovudine results in increased expression of FASLG mRNA]27238871
D006835HydrazonesHydrazones results in increased expression of FASLG mRNA22056764
D006861Hydrogen Peroxide[Clozapine analog co-treated with Hydrogen Peroxide] results in increased expression of FASLG mRNA16510162
D006861Hydrogen Peroxide[Clozapine co-treated with Hydrogen Peroxide co-treated with Tretinoin] results in increased expression of FASLG mRNA16510162
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of FASLG mRNA21347231
D006861Hydrogen Peroxide"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Hydrogen Peroxide results in increased expression of FASLG protein]"15799720
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of FASLG protein15799720
C031927hydroquinonehydroquinone results in increased expression of FASLG protein23776099
C013038hydroxyhydroquinonehydroxyhydroquinone results in increased expression of FASLG protein23776099
C428264indioside Dindioside D results in increased expression of FASLG protein18376857
D007213IndomethacinIndomethacin results in increased expression of FASLG mRNA18375387
D007213IndomethacinLansoprazole inhibits the reaction [Indomethacin results in increased expression of FASLG mRNA]18375387
D007288InosineInosine results in increased expression of FASLG protein16419169
D015759IonomycinTamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA]20529085
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA20529085
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG protein20529085
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG mRNA20529085
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG protein20529085
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FASLG mRNA25613284
C506002ircinin-1ircinin-1 results in increased expression of FASLG mRNA16163705
C506002ircinin-1ircinin-1 results in increased expression of FASLG protein16163705
C051890irinotecan[selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG15897249
D007530IsofluraneIsoflurane results in decreased expression of FASLG mRNA16978161
D007545IsoproterenolIsoproterenol results in increased expression of FASLG protein19001025
C561695(+)-JQ1 compound[(+)-JQ1 compound co-treated with vemurafenib] results in increased expression of FASLG protein27169980
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of FASLG mRNA26752646
D064747LansoprazoleLansoprazole inhibits the reaction [Indomethacin results in increased expression of FASLG mRNA]18375387
D001556LindaneLindane results in increased expression of FASLG protein19038305
C002385linsidomine[linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
C002385linsidomine[linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of FASLG mRNA"11578593
D008070Lipopolysaccharides[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of FASLG mRNA22777745
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of FASLG mRNA12057914
D019808LosartanLosartan results in decreased expression of FASLG mRNA10925121
D008148LovastatinLovastatin inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]17088865
C015329lycopenelycopene results in decreased expression of FASLG mRNA16886892
D008277Magnesium Oxide[Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FASLG mRNA]27920530
C013099mancozebmancozeb results in increased expression of FASLG protein22289270
C025340manganese chloridebafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]28378122
C025340manganese chlorideCA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of FASLG protein]28378122
C025340manganese chloridemanganese chloride results in increased expression of FASLG protein21704098|2837812
C025340manganese chloridepepstatin inhibits the reaction [manganese chloride results in increased expression of FASLG protein]28378122
D009637MasoprocolMasoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of FASLG protein]17651887
D017258Medroxyprogesterone Acetate[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of FASLG protein16709600
D008550MelatoninMelatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FASLG protein]14993511
D008694MethamphetamineMethamphetamine results in increased expression of FASLG mRNA15644446
D008694MethamphetamineMethamphetamine results in increased expression of FASLG protein15644446
D008731MethoxychlorMethoxychlor results in increased expression of FASLG protein20227399
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in decreased expression of FASLG protein24821435
D015735MifepristoneMifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]12645856
D015735MifepristoneMifepristone results in increased expression of FASLG mRNA16009178
D008934MitogensMitogens results in increased expression of FASLG protein15895164
D016685MitomycinMitomycin results in increased expression of FASLG16019139
D016685MitomycinMitomycin results in increased expression of FASLG mRNA16957513
D016685MitomycinMitomycin results in increased expression of FASLG protein16186332|1695751
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of FASLG mRNA17481689
C008548morinmorin results in increased expression of FASLG mRNA28689916
D009151Mustard GasIL10 protein affects the reaction [Mustard Gas affects the expression of FASLG mRNA]16173061
D009151Mustard GasMustard Gas results in increased expression of FASLG mRNA16173061
D009151Mustard GasMustard Gas results in increased expression of FASLG protein12482751
D009151Mustard GasTNF protein affects the reaction [Mustard Gas affects the expression of FASLG mRNA]16173061
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide[sodium arsenite co-treated with N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide] results in increased localization of and results in increased stability of FASLG protein16487513
C078131N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamideN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide results in increased expression of FASLG protein12721755
C500617NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt[Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FASLG16166447
D009288Naproxen[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FASLG protein]22150557
D009288NaproxenNaproxen inhibits the reaction [Capsaicin results in increased expression of FASLG protein]22150557
C101954N-caproylsphingosine[linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
C101954N-caproylsphingosineN-caproylsphingosine results in increased activity of FASLG promoter10811113
C101954N-caproylsphingosine[S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
C101954N-caproylsphingosine[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
C101954N-caproylsphingosine[spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
D009532NickelNickel results in increased expression of FASLG mRNA24768652
D009538NicotineNicotine results in increased expression of FASLG mRNA18247414|1989649
D009538NicotineNicotine results in increased expression of FASLG protein20383341
D009538NicotineNicotine affects the expression of FASLG mRNA20426880
D009538NicotineNicotine results in increased expression of FASLG protein alternative form18203686
D015376NimustineNimustine results in increased expression of FASLG mRNA26418950
D015376Nimustinepyrazolanthrone inhibits the reaction [Nimustine results in increased expression of FASLG mRNA]26418950
D009569Nitric Oxide[linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D009569Nitric Oxide[linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
D009569Nitric OxideNitric Oxide inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D009569Nitric Oxide[S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D009569Nitric Oxide[S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
D009569Nitric Oxide[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D009569Nitric Oxide[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
D009569Nitric Oxide[spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D009569Nitric Oxide[spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
D009589Nitrogen OxidesNitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of FASLG protein]16041517
D026423S-Nitroso-N-Acetylpenicillamine[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D026423S-Nitroso-N-Acetylpenicillamine[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
D026422S-Nitrosoglutathione[S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
D026422S-Nitrosoglutathione[S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
D015739Nocodazole[TYMP co-treated with Nocodazole] results in decreased expression of FASLG mRNA15907805
D015739Nocodazole[TYMP co-treated with Nocodazole] results in decreased expression of FASLG protein15907805
C063998nodularinnodularin results in increased expression of FASLG mRNA21262250
C063998nodularinnodularin results in increased expression of FASLG protein21262250
C063998nodularinRELA mutant form inhibits the reaction [nodularin results in increased expression of FASLG mRNA]21262250
C063998nodularinRELA mutant form inhibits the reaction [nodularin results in increased expression of FASLG protein]21262250
C097760N-palmitoylsphingosineFASLG protein results in increased abundance of N-palmitoylsphingosine20061541
C482205nutlin 3nutlin 3 promotes the reaction [FAS protein binds to FASLG protein]21509038
C482205nutlin 3[nutlin 3 promotes the reaction [FAS protein binds to FASLG protein]] which results in increased susceptibility to Cisplatin21509038
C025589ochratoxin Aochratoxin A results in increased expression of FASLG mRNA19562491
D015282OctreotideOctreotide results in increased expression of FASLG protein18642777
C016340o,p'-DDT"o,p'-DDT results in increased expression of FASLG mRNA"22609851
C016340o,p'-DDT"o,p'-DDT analog results in decreased expression of FASLG mRNA"22937105
C016340o,p'-DDT"o,p'-DDT results in increased expression of FASLG mRNA"22937105
D008939MitotaneMitotane results in increased expression of FASLG mRNA23485034
D010100Oxygen"3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]"23452621
D010100OxygenCurcumin inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]23452621
D010100OxygenGenistein inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]23452621
D010100OxygenOxygen deficiency results in increased expression of FASLG mRNA23452621
D010100OxygenPlant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]23452621
D010100Oxygenresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]23452621
D017239Paclitaxel[esculetin co-treated with Paclitaxel] results in increased expression of FASLG protein16051289
D017239PaclitaxelFASLG protein results in increased susceptibility to Paclitaxel18074150
D017239PaclitaxelPaclitaxel results in increased expression of FASLG mRNA15907805
D017239PaclitaxelPaclitaxel results in increased expression of FASLG protein10502406|1171636
D017239PaclitaxelTYMP inhibits the reaction [Paclitaxel results in increased expression of FASLG mRNA]15907805
D017239PaclitaxelTYMP inhibits the reaction [Paclitaxel results in increased expression of FASLG protein]15907805
D017239PaclitaxelBCL2L1 protein inhibits the reaction [Paclitaxel results in increased expression of FASLG protein]11716366
D010269ParaquatParaquat results in increased expression of FASLG mRNA27288846
D010269ParaquatParaquat results in increased expression of FASLG mRNA18836921
C002669parthenolideparthenolide results in decreased expression of FASLG mRNA16024633
C100442PD 150606PD 150606 inhibits the reaction [FASLG protein results in increased activity of CAPN1 protein]23283937
C074968pentaacetyl geniposideMasoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of FASLG protein]17651887
C074968pentaacetyl geniposidepentaacetyl geniposide results in increased expression of FASLG protein17651887
D010424PentobarbitalPentobarbital results in decreased expression of FASLG mRNA16978161
C031375pepstatinpepstatin inhibits the reaction [manganese chloride results in increased expression of FASLG protein]28378122
C011272perfosfamideperfosfamide results in increased expression of FASLG mRNA14760101
C011272perfosfamideperfosfamide results in increased expression of FASLG protein14760101
D010578PetroleumPetroleum results in increased expression of FASLG protein24106129
D015232DinoprostoneDinoprostone results in increased expression of FASLG15491851
D015232DinoprostoneFASLG results in increased susceptibility to Dinoprostone15491851
D015232DinoprostoneDinoprostone results in decreased expression of FASLG mRNA10427999
D010634PhenobarbitalPhenobarbital affects the expression of FASLG mRNA19084549
D019800PhenolPhenol results in increased expression of FASLG protein23776099
C006253pirinixic acidpirinixic acid affects the expression of FASLG mRNA16912651
D010936Plant ExtractsPlant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]23452621
D010936Plant ExtractsPlant Extracts results in decreased expression of FASLG protein24677778
D010936Plant ExtractsPlant Extracts results in increased expression of FASLG protein26122529
D010936Plant ExtractsPlant Extracts results in increased expression of FASLG mRNA26332274
D028321Plant PreparationsPlant Preparations results in increased expression of FASLG mRNA24973489
C005556propionaldehydepropionaldehyde results in decreased expression of FASLG mRNA26079696
D011429PropolisPropolis inhibits the reaction [Doxorubicin results in increased expression of and results in increased activity of FASLG protein]24593989
C033607puerarinarsenic trioxide promotes the reaction [puerarin results in increased expression of FASLG protein]20416161
C033607puerarinpuerarin results in increased expression of FASLG protein20416161
D011692Puromycin AminonucleosideMelatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FASLG protein]14993511
C432165pyrazolanthronepyrazolanthrone affects the reaction [temozolomide results in increased expression of FASLG mRNA]26418950
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Nimustine results in increased expression of FASLG mRNA]26418950
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Quercetin results in increased expression of FASLG protein]21165570
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [[sorafenib co-treated with Vitamin K 1] results in increased expression of FASLG protein]20301194
D011794Quercetin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of FASLG protein]21165570
D011794Quercetinpyrazolanthrone inhibits the reaction [Quercetin results in increased expression of FASLG protein]21165570
D011794QuercetinQuercetin results in increased expression of FASLG mRNA21165570
D011794QuercetinQuercetin results in increased expression of FASLG protein21165570|2429915
D011794Quercetin"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of FASLG mRNA]"21294050
D011794QuercetinQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of FASLG mRNA]24316378
D011794QuercetinQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of FASLG protein]24316378
D011794QuercetinQuercetin results in decreased expression of FASLG mRNA10925121
D017382Reactive Oxygen Species[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of FASLG mRNA22429591
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in increased expression of FASLG mRNA22429591
D017382Reactive Oxygen SpeciesSOD2 protein inhibits the reaction [Reactive Oxygen Species results in increased expression of FASLG]22429591
D017382Reactive Oxygen Species[SOD2 protein results in decreased abundance of Reactive Oxygen Species] which results in decreased activity of FASLG protein22429591
C059514resveratrolresveratrol analog results in increased expression of FASLG mRNA24044363
C059514resveratrolresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]23452621
C059514resveratrolresveratrol promotes the reaction [FOXO3 protein binds to FASLG promoter]17513867
C059514resveratrolresveratrol results in increased cleavage of FASLG protein22644961
C059514resveratrolresveratrol results in increased expression of FASLG mRNA20717957|9680369
C059514resveratrolresveratrol results in increased expression of FASLG protein15217905|2071795
C059514resveratrolSB 203580 promotes the reaction [resveratrol results in increased cleavage of FASLG protein]22644961
C059514resveratrolCDC42 protein mutant form inhibits the reaction [resveratrol results in increased expression of FASLG]15217905
C059514resveratrolMAP3K5 protein promotes the reaction [resveratrol results in increased expression of FASLG]15217905
C059514resveratrolMAPK8 protein affects the reaction [resveratrol results in increased expression of FASLG protein]15217905
D012293RifampinMifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]12645856
D012293RifampinRifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]12645856
D012293RifampinRifampin results in decreased expression of FASLG mRNA11958592|2455268
D012293RifampinRifampin results in decreased expression of FASLG protein11958592
D019438RitonavirRitonavir results in decreased expression of FASLG protein10551732
C089730rosiglitazonerosiglitazone inhibits the reaction [Streptozocin results in increased expression of FASLG mRNA]21791967
D015575RoxithromycinRoxithromycin results in increased expression of FASLG protein12921874
C005705sanguinarine[sanguinarine co-treated with arsenic trioxide] results in increased expression of FASLG mRNA24345465
C093642SB 203580SB 203580 affects the reaction [temozolomide results in increased expression of FASLG mRNA]26418950
C093642SB 203580SB 203580 promotes the reaction [Emodin results in increased expression of FASLG protein]27032576
C093642SB 203580SB 203580 promotes the reaction [resveratrol results in increased cleavage of FASLG protein]22644961
D012643Selenium[Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FASLG mRNA]27920530
C002979selenomethylselenocysteine[selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG15897249
C040115shogaolshogaol results in increased expression of FASLG protein18384088
D019821SimvastatinSimvastatin results in decreased expression of FASLG mRNA17313769
D020123SirolimusSirolimus results in decreased secretion of FASLG protein11692113
C110881S-nitro-N-acetylpenicillamineFASLG results in increased susceptibility to S-nitro-N-acetylpenicillamine15491851
C017947sodium arsenitesodium arsenite results in decreased expression of FASLG mRNA20308225
C017947sodium arsenitesodium arsenite affects the activity of FASLG protein18977016
C017947sodium arsenite[sodium arsenite co-treated with FASLG protein] results in increased cleavage of CASP3 protein18977016
C017947sodium arsenite[sodium arsenite co-treated with FASLG protein] results in increased cleavage of PARP1 protein18977016
C017947sodium arsenite[sodium arsenite co-treated with N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide] results in increased localization of and results in increased stability of FASLG protein16487513
C017947sodium arsenite[Atorvastatin Calcium co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]20946910
C017947sodium arsenitesodium arsenite results in increased expression of FASLG protein20946910
D0150862,6-Dichloroindophenol"[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of FASLG mRNA"21034357
D012969Sodium FluorideSodium Fluoride results in increased expression of FASLG mRNA19852076
D012989Soil PollutantsSoil Pollutants results in decreased expression of FASLG protein23953925
D012989Soil PollutantsSoil Pollutants results in increased expression of FASLG mRNA23953925
C471405sorafenibpyrazolanthrone inhibits the reaction [[sorafenib co-treated with Vitamin K 1] results in increased expression of FASLG protein]20301194
C471405sorafenib[sorafenib co-treated with Vitamin K 1] results in increased expression of FASLG protein20301194
C091861spermine nitric oxide complex[spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]10811113
C091861spermine nitric oxide complex[spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]10811113
D013311Streptozocinrosiglitazone inhibits the reaction [Streptozocin results in increased expression of FASLG mRNA]21791967
D013311StreptozocinStreptozocin results in increased expression of FASLG mRNA21791967
C016766sulforafansulforafan results in increased expression of FASLG protein26833863
D018170Sumatriptan[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FASLG protein]22150557
D018170SumatriptanSumatriptan inhibits the reaction [Capsaicin results in increased expression of FASLG protein]22150557
C446685systhanesysthane results in decreased expression of FASLG mRNA25461557
D016559TacrolimusTacrolimus results in decreased secretion of FASLG protein11692113
D013629TamoxifenTamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA]20529085
D013629TamoxifenTamoxifen results in decreased expression of FASLG mRNA20145137
D013629TamoxifenTamoxifen results in increased expression of FASLG protein12721755
D013629Tamoxifen[Tamoxifen results in increased expression of TGFB1 protein] which results in increased expression of FASLG mRNA20145137
D013629TamoxifenTamoxifen inhibits the reaction [Estradiol results in increased expression of FASLG protein]15545282
C084178telmisartantelmisartan inhibits the reaction [Cadmium Chloride results in increased expression of FASLG protein]21819444
C047246temozolomidepyrazolanthrone affects the reaction [temozolomide results in increased expression of FASLG mRNA]26418950
C047246temozolomideSB 203580 affects the reaction [temozolomide results in increased expression of FASLG mRNA]26418950
C047246temozolomidetemozolomide results in increased expression of FASLG mRNA26418950
D013739Testosterone[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG mRNA20529085
D013739Testosterone[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG protein20529085
D013739TestosteroneCarbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of FASLG mRNA]24658017
D013739TestosteroneFlutamide inhibits the reaction [Testosterone results in increased expression of FASLG mRNA]24658017
D013739TestosteroneTestosterone deficiency results in decreased expression of FASLG protein20850791
D013739TestosteroneTestosterone inhibits the reaction [Diethylstilbestrol results in increased expression of FASLG protein]12477725
D013739TestosteroneTestosterone results in increased expression of FASLG mRNA24658017
D013739Testosteronetetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Testosterone results in increased expression of FASLG mRNA]24658017
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of FASLG mRNA24349563
D013749TetrachlorodibenzodioxinCycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FASLG mRNA]11007951
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of FASLG mRNA11007951
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of FASLG mRNA19520675
D013755Tetradecanoylphorbol AcetateTamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA]20529085
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA20529085
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG protein20529085
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG mRNA20529085
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG protein20529085
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FASLG mRNA25613284
C050950tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complextetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Testosterone results in increased expression of FASLG mRNA]24658017
D013792ThalidomideThalidomide results in decreased expression of FASLG protein16531263
D013936ThymidineThymidine results in increased expression of FASLG protein16419169
C512542thymoglobulinthymoglobulin results in increased expression of FASLG protein15919515
C032628tin protoporphyrin IXtin protoporphyrin IX inhibits the reaction [FASLG protein results in increased activity of CASP3 protein]16051694
C032628tin protoporphyrin IXtin protoporphyrin IX inhibits the reaction [FASLG protein results in increased activity of CASP8 protein]16051694
C032628tin protoporphyrin IXtin protoporphyrin IX inhibits the reaction [FASLG protein results in increased cleavage of CASP3 protein]16051694
C518838Titanocene YTitanocene Y results in increased expression of FASLG mRNA21986259
C513941tongxinluotongxinluo results in decreased expression of FASLG mRNA17313769
D014212Tretinoin[Clozapine co-treated with Hydrogen Peroxide co-treated with Tretinoin] results in increased expression of FASLG mRNA16510162
D014212TretinoinTretinoin results in decreased expression of FASLG mRNA16957513
D014212TretinoinTretinoin results in decreased expression of FASLG protein16957513
D014241TrichloroethyleneTrichloroethylene results in increased methylation of FASLG gene27618143
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of FASLG mRNA17481689
C050414tripterinetripterine results in increased expression of FASLG protein21466843
C057693troglitazonetroglitazone results in increased expression of FASLG mRNA19631733
C113580U 0126U 0126 promotes the reaction [Emodin results in increased expression of FASLG protein]27032576
D014501UraniumUranium results in increased expression of FASLG mRNA16854789
D014529UridineUridine results in increased expression of FASLG protein16419169
C073339usnic acid[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of FASLG mRNA22777745
C503870vacuolin-1vacuolin-1 results in decreased activity of FASLG protein20061541
D000068756Valsartanbenazepril promotes the reaction [Valsartan inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]]15315341
D000068756ValsartanValsartan inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]15315341
D000068756ValsartanValsartan promotes the reaction [benazepril inhibits the reaction [Doxorubicin results in increased expression of FASLG protein]]15315341
C551177vemurafenib[(+)-JQ1 compound co-treated with vemurafenib] results in increased expression of FASLG protein27169980
D014747VinblastineVinblastine results in increased expression of FASLG protein11716366
D014750VincristineVincristine results in increased expression of FASLG protein11716366
D010837Vitamin K 1pyrazolanthrone inhibits the reaction [[sorafenib co-treated with Vitamin K 1] results in increased expression of FASLG protein]20301194
D010837Vitamin K 1[sorafenib co-treated with Vitamin K 1] results in increased expression of FASLG protein20301194
C111237vorinostat[Bortezomib co-treated with vorinostat] results in increased expression of FASLG mRNA17351739
C111237vorinostat[Bortezomib co-treated with vorinostat] results in increased expression of FASLG protein17351739
C111237vorinostatCurcumin inhibits the reaction [[vorinostat co-treated with Bortezomib] results in increased expression of FASLG protein]17351739
C111237vorinostatvorinostat results in increased expression of FASLG mRNA17351739
C111237vorinostatvorinostat results in increased expression of FASLG protein17351739|1802528
C009687wortmanninwortmannin inhibits the reaction [evodiamine results in increased expression of FASLG protein]20005289
C108830Y 27632Y 27632 inhibits the reaction [Cisplatin results in increased expression of FASLG mRNA]20878077
C108830Y 27632Y 27632 results in decreased expression of FASLG mRNA20878077
D015215Zidovudine[Acrolein co-treated with Zidovudine] results in increased expression of FASLG protein27238871
D015215ZidovudineAcrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]27238871
D015215ZidovudineAcrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]27238871
D015215ZidovudineHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]]27238871
D015215ZidovudineHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]27238871
D015215ZidovudineHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]]27238871
D015215ZidovudineHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]27238871
D015215ZidovudineHydralazine inhibits the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]27238871
D015215ZidovudineHydralazine inhibits the reaction [Zidovudine results in increased expression of FASLG mRNA]27238871
D015215ZidovudineZidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]27238871
D015215ZidovudineZidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]27238871
D015215ZidovudineZidovudine promotes the reaction [RELA protein binds to FASLG promoter]27238871
D015215ZidovudineZidovudine results in increased expression of FASLG mRNA27238871
D015215ZidovudineZidovudine results in increased expression of FASLG protein17943461
D015215ZidovudineAcrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]27238871
D015215ZidovudineHydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]27238871
D015215ZidovudineHydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]27238871
D015215ZidovudineHydralazine inhibits the reaction [Zidovudine results in increased expression of FASLG mRNA]27238871
D015215ZidovudineZidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]27238871
D015215ZidovudineZidovudine results in increased expression of FASLG mRNA27238871
D015032ZincZinc deficiency results in decreased expression of FASLG mRNA22171008
D015032ZincZinc results in increased expression of FASLG protein16472982
D015032ZincAcetylcysteine inhibits the reaction [Zinc results in increased expression of FASLG protein]11864783
D015032ZincZinc results in increased expression of FASLG mRNA11864783
D015032ZincZinc results in increased expression of FASLG protein11864783
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP3 protein]16051694
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP8 protein]16051694
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [FASLG protein results in increased cleavage of CASP3 protein]16051694
C000588918ziyuglycoside IIMAPK8 mutant form inhibits the reaction [ziyuglycoside II results in increased expression of FASLG protein]24680927
C000588918ziyuglycoside IIziyuglycoside II results in increased expression of FASLG protein24680927
C088658zoledronic acidzoledronic acid affects the expression of FASLG mRNA19036117

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005102signaling receptor binding-TAS7826947  
GO:0005123death receptor binding-IEA-  
GO:0005125cytokine activity-IEA-  
GO:0005164tumor necrosis factor receptor binding-IEA-  
GO:0005515protein binding-IPI12198154  12887920  16318909  16498403  16595635  17761170  
19807924  21803845  24025841  25241761  25416956  26871637  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IDA17557115  
GO:0006351transcription, DNA-templated-IEA-  
GO:0006915apoptotic process-TAS8787672  
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process-IGI19364818  
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process-IMP18293083  
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process-TAS-  
GO:0006925inflammatory cell apoptotic process-IEA-  
GO:0006955immune response-IEA-  
GO:0007165signal transduction-TAS7826947  
GO:0007267cell-cell signaling-TAS7826947  
GO:0008284positive regulation of cell proliferation-IEA-  
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors-IDA18835034  26582200  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0016525negative regulation of angiogenesis-IDA18835034  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0030644cellular chloride ion homeostasis-IEA-  
GO:0032496response to lipopolysaccharide-IEA-  
GO:0043065positive regulation of apoptotic process-IDA14749367  21625644  
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling-IEP12761501  
GO:0043525positive regulation of neuron apoptotic process-IEA-  
GO:0045742positive regulation of epidermal growth factor receptor signaling pathway-IEA-  
GO:0046666retinal cell programmed cell death-IEA-  
GO:0048388endosomal lumen acidification-IEA-  
GO:0070231T cell apoptotic process-IDA17076679  
GO:0070266necroptotic process-IDA11101870  
GO:0070848response to growth factor-IEA-  
GO:0097190apoptotic signaling pathway-IDA11101870  
GO:0097190apoptotic signaling pathway-TAS-  
GO:0097191extrinsic apoptotic signaling pathway-IDA22891283  
GO:0097527necroptotic signaling pathway-IDA11101870  
GO:1902041regulation of extrinsic apoptotic signaling pathway via death domain receptors-TAS-  
GO:1902042negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-TAS-  
GO:1903514release of sequestered calcium ion into cytosol by endoplasmic reticulum-IDA26582200  
GO:2000353positive regulation of endothelial cell apoptotic process-IDA18835034  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IDA18835034  
GO:0005634nucleus-IDA17557115  
GO:0005886plasma membrane-IDA12201652  
GO:0005887integral component of plasma membrane-TAS7826947  
GO:0005901caveola-IEA-  
GO:0009897external side of plasma membrane-IEA-  
GO:0043202lysosomal lumen-IEA-  
GO:0048471perinuclear region of cytoplasm-IEA-  
GO:0060205cytoplasmic vesicle lumen-IEA-  
GO:0070062extracellular exosome-IDA17076679  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa04210Apoptosis
hsa04650Natural killer cell mediated cytotoxicity
hsa04722Neurotrophin signaling pathway
hsa04940Type I diabetes mellitus
hsa05142Chagas disease (American trypanosomiasis)
hsa05143African trypanosomiasis
hsa05200Pathways in cancer
hsa05320Autoimmune thyroid disease
hsa05330Allograft rejection
hsa05332Graft-versus-host disease
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisTAS
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-140534Ligand-dependent caspase activationTAS
R-HSA-162582Signal TransductionTAS
R-HSA-1643685DiseaseTAS
R-HSA-168256Immune SystemTAS
R-HSA-3371378Regulation by c-FLIPTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-5213460RIPK1-mediated regulated necrosisTAS
R-HSA-5218859Regulated NecrosisTAS
R-HSA-5218900CASP8 activity is inhibitedTAS
R-HSA-5357769Caspase activation via extrinsic apoptotic signalling pathwayTAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5668541TNFR2 non-canonical NF-kB pathwayTAS
R-HSA-5669034TNFs bind their physiological receptorsTAS
R-HSA-5675482Regulation of necroptotic cell deathTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-69416Dimerization of procaspase-8TAS
R-HSA-73887Death Receptor SignallingTAS
R-HSA-75157FasL/ CD95L signalingTAS
R-HSA-8862803Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease modelsTAS
R-HSA-8863678Neurodegenerative DiseasesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28348007Genome-Wide Analysis of DNA Methylation and Acute Coronary Syndrome. (2017 May 26)Li JCirc Res
28631723Pharmacogenetic biomarkers of response in Crohn's disease. (2018 Jan)Linares-Pineda TMPharmacogenomics J
23991993B-cell Lymphoma 2 rs17757541 C>G polymorphism was associated with an increased risk of gastric cardiac adenocarcinoma in a Chinese population. (2013)Li QAsian Pac J Cancer Prev
18757527Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer. (2008 Nov)Ter-Minassian MCarcinogenesis