Gene: IL5

3567
EDF|IL-5|TRF
interleukin 5
protein-coding
5q31.1
Ensembl:ENSG00000113525 MIM:147850 Vega:OTTHUMG00000059496 UniprotKB:P05113
NG_033019.1
PubMed
ND
5   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.997e-1 (AD)  1.570e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KRT33A0.712
SRMS0.685
TMEM950.672
DEC10.663
FOXA30.662
TMPRSS90.636
CRYBA40.629
CRX0.619
TPRX10.601
SLC25A470.596

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLITRK4-0.254
LRRC10B-0.251
KCNMB2-0.25
RASSF7-0.238
ASIC2-0.235
CHST8-0.232
SHD-0.232
CHAD-0.228
HYAL3-0.227
PLD5-0.225

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01411PranlukastSmall Molecule103177-37-3Approved|InvestigationalTarget
DB06602ReslizumabBiotechDrugApproved|InvestigationalTarget
DB06612MepolizumabBiotechDrug196078-29-2Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0514521,2,3,7,8-pentachlorodibenzo-p-dioxin"1,2,3,7,8-pentachlorodibenzo-p-dioxin analog results in decreased expression of IL5 protein"19041680
C0514521,2,3,7,8-pentachlorodibenzo-p-dioxin"1,2,3,7,8-pentachlorodibenzo-p-dioxin analog results in increased expression of IL5 mRNA"19041680
C0514521,2,3,7,8-pentachlorodibenzo-p-dioxin"1,2,3,7,8-pentachlorodibenzo-p-dioxin results in decreased expression of IL5 protein"19041680
C5031181,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate"1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate results in decreased expression of IL5 protein"15821026
C5031181,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate"1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate results in decreased expression of IL5 protein"15821026
C04676015-acetyldeoxynivalenol15-acetyldeoxynivalenol affects the secretion of IL5 protein8560498
C0152621,6-hexamethylene diisocyanate"1,6-hexamethylene diisocyanate results in increased secretion of IL5 protein"17693426
C0044821-aminopyrene1-aminopyrene results in increased secretion of IL5 protein19879285
C5815721-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea results in decreased expression of IL5 mRNA25827057
C5528882-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide"2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide results in decreased expression of IL5 protein"19458046
C0668412,3,7,8-tetrabromodibenzo-4-dioxin"2,3,7,8-tetrabromodibenzo-4-dioxin results in decreased expression of IL5 protein"19041680
C4754702,3-dimethoxy-6,6-dimethyl-5,6-dihydrobenzo(7,8)indolizino (2,3-b)quinoxaline"2,3-dimethoxy-6,6-dimethyl-5,6-dihydrobenzo(7,8)indolizino (2,3-b)quinoxaline inhibits the reaction [IL5 protein binds to IL5RA protein]"15790522
C4754702,3-dimethoxy-6,6-dimethyl-5,6-dihydrobenzo(7,8)indolizino (2,3-b)quinoxaline"2,3-dimethoxy-6,6-dimethyl-5,6-dihydrobenzo(7,8)indolizino (2,3-b)quinoxaline inhibits the reaction [IL5 protein binds to IL5RA protein]"15182727
C4469992,6-diaminohexanoic acid (4-(5-fluorobenzothiazol-2-yl)-2-methylphenyl)amide"2,6-diaminohexanoic acid (4-(5-fluorobenzothiazol-2-yl)-2-methylphenyl)amide results in increased expression of IL5 protein"23143926
C0038982-anisidine2-anisidine results in increased expression of IL5 mRNA28089782
C5224582-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid"2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]"17475810
C0188552-tert-butylhydroquinone[2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased expression of and results in increased secretion of IL5 protein22250088
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL5 mRNA"28351761
C0059753,4-dihydroxyphenylethanol"[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of IL5 mRNA"16797527
C0432473-acetyldeoxynivalenol3-acetyldeoxynivalenol affects the secretion of IL5 protein8560498
C4755683-aminobenzanthrone3-aminobenzanthrone results in increased expression of IL5 mRNA19879285
C0466933-aminofluoranthene3-aminofluoranthene results in increased secretion of IL5 protein19879285
C0068214-bromophenacyl bromide4-bromophenacyl bromide results in decreased expression of IL5 protein15454121
C0729564-nitrososulfamethoxazole4-nitrososulfamethoxazole results in increased secretion of IL5 protein22331489
C5527705-(cyclohexylmethoxy)-3-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one"5-(cyclohexylmethoxy)-3-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one results in decreased activity of IL5 protein"20472438
C0417156-anilino-5,8-quinolinedione"6-anilino-5,8-quinolinedione results in decreased secretion of IL5 protein"16533816
D019342Acetic AcidAcetic Acid results in decreased expression of IL5 protein16806339
D000096Acetone[Acetone co-treated with Olive Oil] results in increased expression of IL5 mRNA21252390
D000109AcetylcholineIL5 protein results in increased susceptibility to Acetylcholine11897983
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL5 protein]26138014
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL5 protein]20431929
D037361Adenylate Cyclase ToxinAdenylate Cyclase Toxin results in increased expression of IL5 protein14977963
D000276Adjuvants, Immunologic"Adjuvants, Immunologic results in increased secretion of IL5 protein"22967010
D000305Adrenal Cortex HormonesAdrenal Cortex Hormones inhibits the reaction [IL5 protein results in increased expression of IL5RA protein]10224351
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of IL5 gene27153756
C430898AGN 194204AGN 194204 results in increased secretion of IL5 protein11970994
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in increased expression of IL5 protein"25172162
D000395Air Pollutants, Occupational"TLR4 protein affects the reaction [Air Pollutants, Occupational results in increased expression of IL5 protein]"25172162
D000420Albuterol1-Methyl-3-isobutylxanthine promotes the reaction [Albuterol inhibits the reaction [IL5 protein results in increased abundance of Superoxides]]16238794
D000420AlbuterolAlbuterol inhibits the reaction [IL5 protein results in increased abundance of Superoxides]16238794
D000420AlbuterolICI 118551 inhibits the reaction [Albuterol inhibits the reaction [IL5 protein results in increased abundance of Superoxides]]16238794
C021137alclometasone dipropionatealclometasone dipropionate results in decreased expression of IL5 protein11407316
C103303alitretinoinalitretinoin results in increased expression of IL5 mRNA17118196
C103303alitretinoinalitretinoin results in increased expression of IL5 protein17118196
D000485AllergensAllergens results in decreased expression of IL5 protein17669578
D000485Allergensbis(tri-n-butyltin)oxide inhibits the reaction [Allergens results in increased expression of IL5 protein]17669578
D000535AluminumAluminum results in increased secretion of IL5 protein22967010
D000536Aluminum HydroxideAluminum Hydroxide results in increased expression of IL5 mRNA9328138
C026967Amb a I protein, Ambrosia artemisiifolia"Amb a I protein, Ambrosia artemisiifolia results in increased expression of IL5 mRNA"10075860
C026967Amb a I protein, Ambrosia artemisiifolia"Fluticasone inhibits the reaction [Amb a I protein, Ambrosia artemisiifolia results in increased expression of IL5 mRNA]"10075860
C026967Amb a I protein, Ambrosia artemisiifolia"[Particulate Matter co-treated with Amb a I protein, Ambrosia artemisiifolia] results in increased expression of IL5 mRNA"9036991
C026967Amb a I protein, Ambrosia artemisiifolia"[Vehicle Emissions co-treated with Amb a I protein, Ambrosia artemisiifolia] results in increased expression of IL5 mRNA"9036991
D000643Ammonium ChlorideAmmonium Chloride affects the expression of IL5 mRNA16483693
D039741Antigens, Dermatophagoides"Antigens, Dermatophagoides results in increased expression of IL5 mRNA"11167953
D039741Antigens, Dermatophagoides"Antigens, Dermatophagoides results in increased secretion of IL5 protein"11167953|2326671
D039741Antigens, Dermatophagoides"Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL5 mRNA]"11167953
D039741Antigens, Dermatophagoides"Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL5 protein]"11167953
D039741Antigens, Dermatophagoides"Nanotubes, Carbon inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL5 protein]"23266719
D039741Antigens, Dermatophagoides"[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA"23499868
D039741Antigens, Dermatophagoides"[Antigens, Dermatophagoides co-treated with Nanotubes, Carbon] results in increased expression of IL5 mRNA"26091108
D039741Antigens, Dermatophagoides"Antigens, Dermatophagoides results in increased expression of IL5 mRNA"26091108
D039741Antigens, Dermatophagoides"Antigens, Dermatophagoides results in increased expression of IL5 protein"12435080|2006477
D039741Antigens, Dermatophagoides"Formaldehyde promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL5 protein]"12435080
D039741Antigens, Dermatophagoides"[Methoxychlor co-treated with Antigens, Dermatophagoides] affects the expression of IL5 protein"21864637
D039741Antigens, Dermatophagoides"oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA]"23499868
D039741Antigens, Dermatophagoides"[Parathion co-treated with Antigens, Dermatophagoides] affects the expression of IL5 protein"21864637
D039741Antigens, Dermatophagoides"[Particulate Matter co-treated with Antigens, Dermatophagoides] results in increased expression of and results in increased secretion of IL5 protein"27315767
D039741Antigens, Dermatophagoides"RAG2 protein affects the reaction [[Particulate Matter co-treated with Antigens, Dermatophagoides] results in increased expression of IL5 protein]"27315767
D039741Antigens, Dermatophagoides"RAG2 protein affects the reaction [[Vehicle Emissions co-treated with Antigens, Dermatophagoides] results in increased expression of IL5 protein]"27315767
D039741Antigens, Dermatophagoides"[Vehicle Emissions co-treated with Antigens, Dermatophagoides] results in increased expression of and results in increased secretion of IL5 protein"27315767
D039741Antigens, Dermatophagoides"Antigens, Dermatophagoides results in increased expression of IL5 mRNA"11399795
D039741Antigens, Dermatophagoides"Tetrachlorodibenzodioxin inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL5 mRNA]"11399795
D052179Antigens, Plant"Antigens, Plant results in increased expression of IL5 mRNA"21334316
D052179Antigens, Plant"zopolrestat inhibits the reaction [Antigens, Plant results in increased expression of IL5 mRNA]"21334316
D001194AsbestosAsbestos results in increased expression of IL5 mRNA22398240
D001194AsbestosAsbestos results in increased expression of IL5 protein18795166
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of IL5 protein"26119930
D001280AtrazineAtrazine results in decreased expression of IL5 protein10883730|1531917
D001280AtrazineAtrazine results in decreased expression of IL5 protein12504806
D001397AzoxymethaneAcetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL5 protein]20431929
D001397AzoxymethaneAzoxymethane results in increased expression of IL5 protein20431929
C416282BAY 11-7085"BAY 11-7085 inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"17015710
D001507Beclomethasone"Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL5 mRNA]"11167953
D001507Beclomethasone"Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL5 protein]"11167953
D001507BeclomethasoneBeclomethasone results in decreased expression of IL5 protein10813552
D001507BeclomethasoneBeclomethasone results in decreased expression of IL5 protein7988651
C065857beclomethasone 17-monopropionatebeclomethasone 17-monopropionate results in decreased expression of IL5 protein10813552
D019324beta-Naphthoflavonebeta-Naphthoflavone promotes the reaction [Plant Extracts results in increased expression of IL5 protein]22491429
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of IL5 mRNA28351761
C020711beryllium sulfateberyllium sulfate results in increased expression of IL5 mRNA9328138
D001624Betamethasone ValerateBetamethasone Valerate results in decreased expression of IL5 protein11407316
D001688Biological ProductsBiological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]23200891
C070515bisindolylmaleimide Ibisindolylmaleimide I results in decreased activity of IL5 protein12562334
C006780bisphenol A[bisphenol A co-treated with OVAL protein] results in increased expression of IL5 mRNA27087817
C006780bisphenol Abisphenol A results in decreased expression of IL5 mRNA25181051
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide inhibits the reaction [Allergens results in increased expression of IL5 protein]17669578
D019819BudesonideBudesonide results in decreased expression of IL5 protein12406821|1508696
D0123684-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone results in decreased expression of IL5 protein15169552
D0123684-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinonecilostazol inhibits the reaction [4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone results in decreased expression of IL5 protein]15169552
D0123684-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinoneSildenafil Citrate inhibits the reaction [4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone results in decreased expression of IL5 protein]15169552
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL5 protein]26138014
D019256Cadmium ChlorideCadmium Chloride results in increased expression of and results in increased secretion of IL5 protein26138014
D002110CaffeineCaffeine results in increased expression of IL5 mRNA28089782
D000001Calcimycin[Calcimycin co-treated with phorbol-12-myristate] results in increased expression of IL5 protein12789233
D000001CalcimycinCalcimycin results in increased expression of IL5 mRNA12789233
D000001CalcimycinCyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]1371491
D000001Calcimycinfisetin inhibits the reaction [[Calcimycin co-treated with phorbol-12-myristate] results in increased expression of IL5 protein]12789233
D000001Calcimycinfisetin inhibits the reaction [Calcimycin results in increased expression of IL5 mRNA]12789233
D000001CalcimycinIL5 protein promotes the reaction [CCL11 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]]12797483
D000001CalcimycinIL5 protein promotes the reaction [CCL5 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]]12797483
D000001Calcimycinkaempferol inhibits the reaction [Calcimycin results in increased expression of IL5 mRNA]12789233
D000001Calcimycin"plant extract, Houttuynia cordata inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]"18325701
D000001CalcimycinQuercetin inhibits the reaction [Calcimycin results in increased expression of IL5 mRNA]12789233
D000001CalcimycinTacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]1371491
D000001Calcimycin[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein1371491
D002211CapsaicinCapsaicin results in decreased expression of IL517306834
D002211CapsaicinCapsaicin results in increased expression of IL5 protein22150557
D002211Capsaicin[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL5 protein]22150557
D002211CapsaicinNaproxen inhibits the reaction [Capsaicin results in increased expression of IL5 protein]22150557
D002211CapsaicinSumatriptan inhibits the reaction [Capsaicin results in increased expression of IL5 protein]22150557
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of IL5 mRNA25827057
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of IL5 protein17412915
D002251Carbon TetrachlorideIL1RL1 protein affects the reaction [Carbon Tetrachloride results in increased expression of IL5 protein]17412915
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of IL5 mRNA12734012
D017332Cetirizine[montelukast co-treated with Cetirizine] results in decreased expression of IL5 protein15061398
D002725ChloroformChloroform results in increased expression of IL5 protein16879906
C433247CilomilastCilomilast results in decreased secretion of IL5 protein11907180
C045645cilostazolcilostazol inhibits the reaction [4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone results in decreased expression of IL5 protein]15169552
C086108clobenpropitclobenpropit affects the expression of IL5 protein17346280
D003024ClozapineClozapine affects the expression of IL5 protein17346280
C000593591coagulin-Lcoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL5 protein]27568862
C018021cobaltous chloridecobaltous chloride results in increased expression of IL5 protein20511350
C018021cobaltous chlorideHIF1A inhibits the reaction [cobaltous chloride results in increased expression of IL5 protein]20511350
D005576ColforsinColforsin inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]11886533
D005576ColforsinColforsin inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]11886533
D005576ColforsinColforsin inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]11886533
D005576ColforsinColforsin inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]11886533
D005576ColforsinColforsin inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]11886533
D005576ColforsinColforsin inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]11886533
D005576ColforsinColforsin inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]11886533
D005576ColforsinColforsin inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]11886533
D005576ColforsinColforsin inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]11886533
D005576ColforsinColforsin inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]11886533
D003300Copper[Thiosemicarbazones binds to Copper] which results in increased expression of IL5 protein20931265
D016578Crack CocaineCrack Cocaine results in increased expression of IL5 protein12947150
D003474CurcuminCurcumin results in decreased expression of IL518462866
D003513CycloheximideCycloheximide results in decreased expression of IL5 protein23150660
D003513CycloheximideTO-901317 inhibits the reaction [Cycloheximide results in decreased expression of IL5 protein]23150660
D003520CyclophosphamideCyclophosphamide results in increased expression of IL5 mRNA11006010
D003520CyclophosphamideCyclophosphamide results in increased expression of IL5 protein11006010
D003520CyclophosphamideCyclophosphamide results in increased expression of IL5 protein18848347
D016572CyclosporineCyclosporine inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]15663561
D016572CyclosporineCyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]1371491
D016572CyclosporineCyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]17475810
D016572CyclosporineCyclosporine results in decreased expression of IL5 protein7540862
D016572CyclosporineCyclosporine results in decreased expression of IL5 protein7988651
D003571Cytochalasin B[Cytochalasin B co-treated with IL5 protein] results in increased secretion of EPO protein18776917
D003571Cytochalasin Bresveratrol analog inhibits the reaction [[Cytochalasin B co-treated with IL5 protein] results in increased secretion of EPO protein]18776917
D0150842,4-Dichlorophenoxyacetic Acid"2,4-Dichlorophenoxyacetic Acid results in increased expression of IL5 protein"19467290
D000069439DasatinibDasatinib results in decreased expression of IL5 protein17962511
D003671DEET[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL5 protein28659758
D013759DronabinolDronabinol results in increased expression of IL5 mRNA12446015
D013759DronabinolSR 144528 inhibits the reaction [Dronabinol results in increased expression of IL5 mRNA]12446015
C007262deoxynivalenoldeoxynivalenol affects the secretion of IL5 protein8560498
C007262deoxynivalenoldeoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]8658534
C007262deoxynivalenoldeoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]8658534
C007262deoxynivalenoldeoxynivalenol results in increased expression of IL5 mRNA8560498
C121345desloratadine[montelukast co-treated with desloratadine] results in decreased expression of IL5 protein15061398
D003907DexamethasoneDexamethasone inhibits the reaction [IL5 protein results in decreased expression of IL5RA protein]14739603
D003907DexamethasoneDexamethasone results in decreased expression of IL5 mRNA10596698|1172476
D003907DexamethasoneDexamethasone results in decreased expression of IL5 protein10883730|1172476
D003907DexamethasoneDexamethasone results in decreased secretion of IL5 protein12871219
D003907DexamethasoneDexamethasone results in decreased stability of and results in decreased expression of IL5 mRNA12871219
D003907Dexamethasone[pranlukast co-treated with Dexamethasone] results in decreased secretion of IL5 protein15650315
D003907DexamethasoneTSC22D3 protein affects the reaction [Dexamethasone results in decreased expression of IL5 mRNA]16243713
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL5 protein]27568862
D003907DexamethasoneDexamethasone results in decreased expression of IL5 protein12504806|1276096
D003907DexamethasoneDexamethasone results in increased expression of IL5 mRNA22842586
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone results in decreased expression of IL5 protein]12504806
D003994BucladesineBucladesine inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]11886533
D003994BucladesineBucladesine inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]11886533
D003994BucladesineBucladesine inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]11886533
D003994BucladesineBucladesine inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]11886533
D003994BucladesineBucladesine inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]11886533
D003994BucladesineBucladesine inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]11886533
D003994BucladesineBucladesine inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]11886533
D003994BucladesineBucladesine inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]11886533
D003994BucladesineBucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]11886533
D003994BucladesineBucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]11886533
D004008DiclofenacDiclofenac inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]15663561
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of IL5 protein25051504
D017259DimapritDimaprit affects the expression of IL5 protein17346280
D004121Dimethyl Sulfoxide"[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA"23751068
D004121Dimethyl Sulfoxide"resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]"23751068
D004121Dimethyl Sulfoxide"Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]"23751068
D004137Dinitrochlorobenzene"[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA"23499868
D004137DinitrochlorobenzeneBiological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]23200891
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of IL5 mRNA23133493|2320089
D004137Dinitrochlorobenzene"oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA]"23499868
D004137DinitrochlorobenzenePlant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]23133493|2345414
D004137DinitrochlorobenzenePrednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]23133493
D004139DinitrofluorobenzeneDinitrofluorobenzene results in increased expression of IL5 protein11418644
D022681Diphtheria-Tetanus-acellular Pertussis VaccinesDiphtheria-Tetanus-acellular Pertussis Vaccines results in increased expression of IL5 protein16299307
D004229DithiothreitolDithiothreitol inhibits the reaction [Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein]]7957178
D004237DiuronDiuron results in decreased expression of IL5 protein10883730
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of IL5 protein"14503063
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of IL5 protein"15644155
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of IL5 protein"16190393
D004391DustMYD88 gene mutant form inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D004391Dust[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein26882889
D004391DustPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D004391DustTLR2 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D004391DustTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D004642EmodinEmodin inhibits the reaction [Ovalbumin results in increased secretion of IL5 protein]22484343
C031818enterotoxin B, staphylococcal"[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA"23751068
C031818enterotoxin B, staphylococcal"resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]"23751068
C031818enterotoxin B, staphylococcal"Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]"23751068
C045651epigallocatechin gallate"epigallocatechin gallate inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"16516891
C053090epinastineepinastine results in decreased expression of IL5 mRNA16534218
C053090epinastineepinastine results in decreased expression of IL5 protein16534218
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of IL5 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of IL5 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IL5 mRNA17942748
C036216ethyleneethylene results in increased expression of IL526367701
C000499ferric oxide[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL5 protein20540983
C017875fisetinfisetin inhibits the reaction [[Calcimycin co-treated with phorbol-12-myristate] results in increased expression of IL5 protein]12789233
C017875fisetinfisetin inhibits the reaction [Calcimycin results in increased expression of IL5 mRNA]12789233
D005419FlavonoidsFlavonoids results in increased expression of IL5 mRNA18035473
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of IL5 protein25051504
D000068298Fluticasone"Fluticasone inhibits the reaction [Amb a I protein, Ambrosia artemisiifolia results in increased expression of IL5 mRNA]"10075860
D000068298FluticasoneFluticasone results in decreased expression of IL5 protein15634547
D005557Formaldehyde"Formaldehyde promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL5 protein]"12435080
D005620Freund's AdjuvantFreund's Adjuvant results in increased expression of IL5 mRNA9328138
C012986furfuryl alcoholfurfuryl alcohol results in increased expression of IL5 protein22003193
D005839GentamicinsGentamicins results in decreased expression of IL5 protein25051504
D005938GlucocorticoidsGlucocorticoids results in decreased expression of IL5 mRNA15835818
D005944GlucosamineGlucosamine results in decreased expression of IL521284687
D005944GlucosamineGlucosamine results in decreased secretion of IL5 protein14507305
C010974glyphosateglyphosate results in increased expression of IL5 protein25172162
C010974glyphosateIL13 protein affects the reaction [glyphosate results in increased expression of IL5 protein]25172162
D006388HemagglutininsHemagglutinins results in increased secretion of IL5 protein22839698
D006581HexachlorobenzeneHexachlorobenzene results in decreased expression of IL5 protein15319175
D006632HistamineTerfenadine inhibits the reaction [Histamine results in increased expression of IL5 protein]12925206
D006851Hydrochloric AcidHydrochloric Acid results in increased expression of IL5 protein19951613
D006854HydrocortisoneHydrocortisone inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]15663561
D006854HydrocortisoneHydrocortisone results in decreased expression of IL5 protein7988651
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of IL5 mRNA12884291
C026777ICI 118551ICI 118551 inhibits the reaction [Albuterol inhibits the reaction [IL5 protein results in increased abundance of Superoxides]]16238794
C114843incomplete Freund's adjuvantincomplete Freund's adjuvant results in increased expression of IL5 mRNA9328138
D015759Ionomycin"2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]"17475810
D015759IonomycinCyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]17475810
D015759Ionomycin[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein17685462
D015759Ionomycinsodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein]17685462
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA17475810
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein17572062
D015759Ionomycindeoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]8658534
D015759Ionomycindeoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]8658534
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA12884291
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]11886533
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine promotes the reaction [Albuterol inhibits the reaction [IL5 protein results in increased abundance of Superoxides]]16238794
C065753isoflavanoneisoflavanone analog results in decreased activity of IL5 protein12767605
D007529IsoflavonesIsoflavones analog results in decreased activity of IL5 protein12767605
D017964Itraconazole1-Methyl-3-isobutylxanthine inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]11886533
D017964Itraconazole1-Methyl-3-isobutylxanthine inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]11886533
D017964ItraconazoleBucladesine inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]11886533
D017964ItraconazoleBucladesine inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]11886533
D017964ItraconazoleColforsin inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]11886533
D017964ItraconazoleColforsin inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]11886533
D017964ItraconazoleItraconazole results in decreased expression of IL5 mRNA11886533|1528482
D017964ItraconazoleItraconazole results in decreased secretion of IL5 protein11886533|1528482
C006552kaempferolkaempferol inhibits the reaction [Calcimycin results in increased expression of IL5 mRNA]12789233
C006552kaempferol"[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of IL5 mRNA"16797527
D007654Ketoconazole1-Methyl-3-isobutylxanthine inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]11886533
D007654Ketoconazole1-Methyl-3-isobutylxanthine inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]11886533
D007654KetoconazoleBucladesine inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]11886533
D007654KetoconazoleBucladesine inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]11886533
D007654KetoconazoleColforsin inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]11886533
D007654KetoconazoleColforsin inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]11886533
D007654KetoconazoleKetoconazole results in decreased expression of IL5 mRNA11886533|1528482
D007654KetoconazoleKetoconazole results in decreased secretion of IL5 protein11886533|1528482
D007840LatexLatex analog results in increased expression of IL5 mRNA24768652
D007854LeadLead results in increased expression of and results in increased secretion of IL5 protein28973681
C008261lead acetatelead acetate results in increased expression of IL5 mRNA20542052
C052901lemongrass oillemongrass oil results in decreased expression of IL5 mRNA25660481
D001556LindaneLindane results in decreased expression of IL5 protein15319175
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of IL5 mRNA19428942
D008070Lipopolysaccharides[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL5 protein18437699
D008070Lipopolysaccharides[Thimerosal co-treated with Lipopolysaccharides] results in increased secretion of IL5 protein17079650
D008070Lipopolysaccharidescoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL5 protein]27568862
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL5 protein]27568862
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL5 protein20851137|2756886
D017997Leukotriene C4IL5 protein results in increased secretion of Leukotriene C49378992
D017998Leukotriene D4Leukotriene D4 promotes the reaction [IL5 protein results in increased expression of TGFB1 protein]15947480
D047311LuteolinLuteolin results in decreased expression of IL5 protein12755373
D058185Magnetite Nanoparticles[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL5 protein20540983
D008627Mercuric ChlorideMercuric Chloride results in increased expression of IL5 protein21984480
D008713MethimazoleMethimazole results in increased expression of IL5 mRNA22407903
D008731Methoxychlor"[Methoxychlor co-treated with Antigens, Dermatophagoides] affects the expression of IL5 protein"21864637
C059330methylene diisocyanatemethylene diisocyanate results in increased secretion of IL5 protein17693426
D008775MethylprednisoloneMethylprednisolone results in decreased expression of IL5 protein7988651
D008825Miconazole1-Methyl-3-isobutylxanthine inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]11886533
D008825Miconazole1-Methyl-3-isobutylxanthine inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]11886533
D008825MiconazoleBucladesine inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]11886533
D008825MiconazoleBucladesine inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]11886533
D008825MiconazoleColforsin inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]11886533
D008825MiconazoleColforsin inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]11886533
D008825MiconazoleMiconazole results in decreased expression of IL5 mRNA11886533|1528482
D008825MiconazoleMiconazole results in decreased secretion of IL5 protein11886533|1528482
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone results in decreased expression of IL5 protein]12504806
C430647monocyte locomotion inhibitory factormonocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL5 protein]16374615
C430647monocyte locomotion inhibitory factormonocyte locomotion inhibitory factor results in increased secretion of IL5 protein16374615
C093875montelukast[montelukast co-treated with Cetirizine] results in decreased expression of IL5 protein15061398
C093875montelukast[montelukast co-treated with desloratadine] results in decreased expression of IL5 protein15061398
C093875montelukastmontelukast results in decreased expression of IL5 mRNA14619337
C005348muconomycin Amuconomycin A affects the secretion of IL5 protein8560498
D009151Mustard GasMustard Gas results in increased expression of IL5 protein17620002
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of IL5 mRNA11886533
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased secretion of IL5 protein11886533
C487056N-AcetylcysteinamideN-Acetylcysteinamide inhibits the reaction [Ovalbumin results in increased expression of IL5 protein]18160846
D037742Nanotubes, Carbon"Nanotubes, Carbon inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL5 protein]"23266719
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of IL5 mRNA"25511174
D037742Nanotubes, Carbon"[Antigens, Dermatophagoides co-treated with Nanotubes, Carbon] results in increased expression of IL5 mRNA"26091108
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of IL5 mRNA"23845593
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased secretion of IL5 protein"19371758
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of IL5 mRNA"22293422|2555468
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of IL5 protein"19428951
D037742Nanotubes, Carbon"[PTGS2 gene mutant form results in increased susceptibility to [Nanotubes, Carbon co-treated with OVAL protein]] which results in increased expression of IL5 mRNA"23642096
D009288Naproxen[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL5 protein]22150557
D009288NaproxenNaproxen inhibits the reaction [Capsaicin results in increased expression of IL5 protein]22150557
D009529NicardipineNicardipine results in decreased secretion of IL5 protein16533816
D009532NickelNickel results in increased expression of IL5 mRNA24768652|2558310
D009532NickelNickel results in increased secretion of IL5 protein15059101
C022838nickel chloride[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL5 protein18437699
C022838nickel chloridenickel chloride results in increased secretion of IL5 protein18437699
C029938nickel sulfateCyclosporine inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]15663561
C029938nickel sulfateDiclofenac inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]15663561
C029938nickel sulfateHydrocortisone inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]15663561
C029938nickel sulfatenickel sulfate results in increased secretion of IL5 protein10929769|1527087
D009569Nitric Oxide[IL5 protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide18206661
D009569Nitric OxideNitric Oxide results in decreased secretion of IL5 protein13678430
D020030Nitric Oxide DonorsNitric Oxide Donors results in decreased secretion of IL5 protein13678430
D026422S-NitrosoglutathioneS-Nitrosoglutathione results in decreased secretion of IL5 protein13678430
C038405nivalenolnivalenol affects the secretion of IL5 protein8560498
C451724NVP ABE171NVP ABE171 results in decreased secretion of IL5 protein11907180
D019787Linoleic AcidLinoleic Acid results in decreased expression of IL5 protein16305726
C052658oleanolic acid 3-acetate"oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA]"23499868
D009844OligosaccharidesOligosaccharides analog results in decreased secretion of IL5 protein15526371
D000069463Olive Oil[Acetone co-treated with Olive Oil] results in increased expression of IL5 mRNA21252390
D010047OvalbuminEmodin inhibits the reaction [Ovalbumin results in increased secretion of IL5 protein]22484343
D010047OvalbuminLTC4S promotes the reaction [Ovalbumin results in increased expression of IL5 protein]21429049
D010047OvalbuminMYD88 gene mutant form inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D010047OvalbuminN-Acetylcysteinamide inhibits the reaction [Ovalbumin results in increased expression of IL5 protein]18160846
D010047Ovalbumin[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein26882889
D010047OvalbuminOvalbumin results in increased expression of IL5 protein18160846|1826115
D010047OvalbuminOvalbumin results in increased secretion of IL5 protein22484343
D010047OvalbuminPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D010047Ovalbumin"thieno(2,3-c)isoquinolin-5-one inhibits the reaction [Ovalbumin results in increased expression of IL5 protein]"18261157
D010047OvalbuminTLR2 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D010047OvalbuminTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D010126OzoneOzone results in decreased expression of IL5 mRNA10226068
D010126Ozone[Vehicle Emissions co-treated with Ozone] results in decreased expression of IL5 protein27058360
D010126Ozone[CPE affects the susceptibility to Ozone] which affects the expression of IL5 mRNA23434795
D010126OzoneIL1RL1 protein affects the reaction [[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of IL5 protein]27472835
D010126Ozone[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of IL5 protein27472835
D010126OzoneOzone results in increased expression of IL5 protein18315731
D010126OzoneTNFRSF1B affects the reaction [[CPE affects the susceptibility to Ozone] which affects the expression of IL5 mRNA]23434795
D010126OzoneOzone results in increased expression of IL5 protein28623178
D010278Parathion"[Parathion co-treated with Antigens, Dermatophagoides] affects the expression of IL5 protein"21864637
D052638Particulate Matter"[Particulate Matter co-treated with Amb a I protein, Ambrosia artemisiifolia] results in increased expression of IL5 mRNA"9036991
D052638Particulate MatterParticulate Matter results in increased expression of IL5 mRNA10075860|8765825
D052638Particulate MatterOVAL protein promotes the reaction [Particulate Matter results in increased expression of IL5 protein]23896513
D052638Particulate Matter"[Particulate Matter co-treated with Antigens, Dermatophagoides] results in increased expression of and results in increased secretion of IL5 protein"27315767
D052638Particulate MatterParticulate Matter promotes the reaction [OVAL protein results in increased expression of IL5 mRNA]20562226
D052638Particulate MatterParticulate Matter results in decreased expression of IL5 mRNA23638009
D052638Particulate MatterParticulate Matter results in decreased expression of IL5 protein18307122
D052638Particulate MatterParticulate Matter results in increased expression of IL520061214
D052638Particulate MatterParticulate Matter results in increased expression of IL5 mRNA16979384|2170821
D052638Particulate MatterParticulate Matter results in increased expression of IL5 protein19074765|2170821
D052638Particulate Matter[Particulate Matter results in increased susceptibility to OVAL protein] which results in increased expression of IL5 mRNA24365139
D052638Particulate Matter[Particulate Matter results in increased susceptibility to OVAL protein] which results in increased expression of IL5 protein24365139|2849585
D052638Particulate Matter[Polycyclic Aromatic Hydrocarbons co-treated with Particulate Matter] results in increased expression of IL5 protein19654922
D052638Particulate Matter"RAG2 protein affects the reaction [[Particulate Matter co-treated with Antigens, Dermatophagoides] results in increased expression of IL5 protein]"27315767
D010416PentachlorophenolPentachlorophenol inhibits the reaction [OVAL protein results in increased expression of IL5 protein]24051191
D010476PerfumePerfume results in increased expression of IL5 mRNA24768652
D026023Permethrin[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL5 protein28659758
D015232DinoprostoneDinoprostone results in increased secretion of IL5 protein15788148
C119222phorbol-12-myristate[Calcimycin co-treated with phorbol-12-myristate] results in increased expression of IL5 protein12789233
C119222phorbol-12-myristatefisetin inhibits the reaction [[Calcimycin co-treated with phorbol-12-myristate] results in increased expression of IL5 protein]12789233
D009764o-Phthalaldehydeo-Phthalaldehyde results in increased expression of IL5 mRNA19110043|2178561
C043103phthalic anhydridephthalic anhydride results in increased expression of IL5 mRNA21252390
C043103phthalic anhydridephthalic anhydride results in increased expression of IL5 protein20219652
C060836pioglitazone"pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"17015710
C006253pirinixic acidpirinixic acid results in decreased expression of IL5 mRNA18249437
C442781plant extract, Houttuynia cordata"plant extract, Houttuynia cordata inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]"18325701
D010936Plant Extractsbeta-Naphthoflavone promotes the reaction [Plant Extracts results in increased expression of IL5 protein]22491429
D010936Plant ExtractsPlant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]23133493|2345414
D010936Plant ExtractsPlant Extracts results in increased expression of IL5 protein22491429
D010936Plant ExtractsPlant Extracts results in increased secretion of IL5 protein21804081
D010936Plant ExtractsTetrachlorodibenzodioxin inhibits the reaction [Plant Extracts results in increased expression of IL5 protein]22491429
D010936Plant ExtractsTetrachlorodibenzodioxin inhibits the reaction [Plant Extracts results in increased secretion of IL5 protein]21804081
D011063Poly A-UPoly A-U results in increased expression of IL5 mRNA9328138
D011084Polycyclic Aromatic Hydrocarbons[Polycyclic Aromatic Hydrocarbons co-treated with Particulate Matter] results in increased expression of IL5 protein19654922
D011112Polymyxin BPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
C467566pomalidomidepomalidomide results in decreased secretion of IL5 protein15292067
C068291poractant alfaporactant alfa results in increased expression of IL5 protein14644929
C047681pranlukast[pranlukast co-treated with Dexamethasone] results in decreased secretion of IL5 protein15650315
C047681pranlukastpranlukast results in decreased expression of IL5 mRNA15650315
C047681pranlukastpranlukast results in decreased secretion of IL5 protein15650315
D011223PraziquantelPraziquantel results in increased expression of IL5 protein15213147
D011239PrednisolonePrednisolone results in decreased expression of IL5 protein15821026
D011239PrednisolonePrednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]23133493
D011241PrednisonePrednisone results in decreased expression of IL5 protein12722970|1552343
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL5 protein28659758
D011794QuercetinQuercetin inhibits the reaction [Calcimycin results in increased expression of IL5 mRNA]12789233
D011794Quercetin"[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of IL5 mRNA"16797527
C046386Quil AQuil A results in increased expression of IL5 mRNA9328138
D017382Reactive Oxygen SpeciesIL5 protein promotes the reaction [CCL11 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]]12797483
D017382Reactive Oxygen SpeciesIL5 protein promotes the reaction [CCL5 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]]12797483
C059514resveratrolresveratrol analog inhibits the reaction [[Cytochalasin B co-treated with IL5 protein] results in increased secretion of EPO protein]18776917
C059514resveratrol"resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]"23751068
C059514resveratrolresveratrol results in decreased expression of IL5 protein22986054|2407324
C009166retinol acetateIL5 protein affects the susceptibility to retinol acetate11444878
C009166retinol acetateretinol acetate results in increased expression of IL5 protein11444878
D012254RibavirinRibavirin results in decreased expression of IL5 protein10770762
C089730rosiglitazone"rosiglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"17015710
C099445S 28463S 28463 results in decreased expression of IL5 protein16361354
C081159secretoneurinsecretoneurin results in increased secretion of IL5 protein15664667
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of IL5 protein"16251409|1720018
D017632Asbestos, Serpentine"PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL5 protein]"17200189
C090832sho-seiryu-to"sho-seiryu-to inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 mRNA]"19050374
D000068677Sildenafil CitrateSildenafil Citrate inhibits the reaction [4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone results in decreased expression of IL5 protein]15169552
D012822Silicon DioxideIL6RA mRNA affects the reaction [Silicon Dioxide results in increased expression of IL5 mRNA]20490462
D012822Silicon DioxideSilicon Dioxide results in increased expression of IL5 mRNA20490462
D012822Silicon DioxideSilicon Dioxide results in increased secretion of IL5 protein20490462
D012834SilverSilver results in decreased secretion of IL5 protein17996693
D020123SirolimusSirolimus analog results in decreased expression of IL5 protein12406821
C016104sodium bichromatesodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein]17685462
D053260SootSoot results in increased expression of IL5 mRNA26551751
C120642sophoricosidesophoricoside results in decreased activity of IL5 protein12767605
C110630SR 144528SR 144528 inhibits the reaction [Dronabinol results in increased expression of IL5 mRNA]12446015
C525422SRT1720SRT1720 inhibits the reaction [OVAL protein results in increased expression of IL5 protein]23062010
D019311StaurosporineStaurosporine results in decreased activity of IL5 protein12562334
D013420SulfamethoxazoleSulfamethoxazole analog results in increased secretion of IL5 protein15588915
D013458Sulfur DioxideSulfur Dioxide promotes the reaction [OVAL protein results in increased expression of IL5 mRNA]29288730
D018170Sumatriptan[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL5 protein]22150557
D018170SumatriptanSumatriptan inhibits the reaction [Capsaicin results in increased expression of IL5 protein]22150557
D013481Superoxides1-Methyl-3-isobutylxanthine promotes the reaction [Albuterol inhibits the reaction [IL5 protein results in increased abundance of Superoxides]]16238794
D013481SuperoxidesAlbuterol inhibits the reaction [IL5 protein results in increased abundance of Superoxides]16238794
D013481SuperoxidesICI 118551 inhibits the reaction [Albuterol inhibits the reaction [IL5 protein results in increased abundance of Superoxides]]16238794
D013605T-2 ToxinT-2 Toxin affects the secretion of IL5 protein8560498
D016559TacrolimusTacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]1371491
D016559TacrolimusTacrolimus results in decreased expression of IL5 mRNA15948978|7540862
D016559TacrolimusTacrolimus results in decreased expression of IL5 protein11407316|1594897
D013629TamoxifenTamoxifen affects the expression of IL5 mRNA17555576
C041359terbinafine1-Methyl-3-isobutylxanthine inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]11886533
C041359terbinafine1-Methyl-3-isobutylxanthine inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]11886533
C041359terbinafineBucladesine inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]11886533
C041359terbinafineBucladesine inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]11886533
C041359terbinafineColforsin inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]11886533
C041359terbinafineColforsin inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]11886533
C041359terbinafineterbinafine results in decreased expression of IL5 mRNA11886533|1528482
C041359terbinafineterbinafine results in decreased secretion of IL5 protein11886533|1528482
D016593TerfenadineTerfenadine inhibits the reaction [Histamine results in increased expression of IL5 protein]12925206
D016593TerfenadineTerfenadine inhibits the reaction [IL4 protein results in increased expression of IL5 mRNA]12925206
D016593TerfenadineTerfenadine inhibits the reaction [IL4 protein results in increased expression of IL5 protein]12925206
D016593TerfenadineTerfenadine results in decreased expression of IL5 protein10469039
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of IL5 mRNA28351761
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IL5 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [OVAL protein results in increased expression of IL5 protein]24051191
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Plant Extracts results in increased expression of IL5 protein]22491429
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Plant Extracts results in increased secretion of IL5 protein]21804081
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IL5 mRNA18684927
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IL5 protein19041680
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of IL5 mRNA12167310|1794274
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL5 mRNA]"11399795
D013755Tetradecanoylphorbol Acetate"2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]"17475810
D013755Tetradecanoylphorbol AcetateCyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]1371491
D013755Tetradecanoylphorbol AcetateCyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]17475810
D013755Tetradecanoylphorbol Acetate[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein17685462
D013755Tetradecanoylphorbol Acetatemonocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL5 protein]16374615
D013755Tetradecanoylphorbol Acetate"plant extract, Houttuynia cordata inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]"18325701
D013755Tetradecanoylphorbol Acetatesodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein]17685462
D013755Tetradecanoylphorbol AcetateTacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]1371491
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein1371491
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA17475810
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein17572062
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of IL5 mRNA16116958
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased secretion of IL5 protein16374615
D013755Tetradecanoylphorbol Acetatedeoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]8658534
D013755Tetradecanoylphorbol Acetatedeoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]8658534
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA12884291
D013792ThalidomideThalidomide results in decreased expression of IL517013434
D013844ThiazolesDithiothreitol inhibits the reaction [Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein]]7957178
D013844ThiazolesThiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein]7957178
C475227thieno(2,3-c)isoquinolin-5-one"thieno(2,3-c)isoquinolin-5-one inhibits the reaction [Ovalbumin results in increased expression of IL5 protein]"18261157
D013849Thimerosal[Thimerosal co-treated with Lipopolysaccharides] results in increased secretion of IL5 protein17079650
D013882Thiosemicarbazones[Thiosemicarbazones binds to Copper] which results in increased expression of IL5 protein20931265
C009495titanium dioxidetitanium dioxide results in increased expression of IL5 mRNA19695317
C009495titanium dioxidetitanium dioxide results in increased expression of IL5 protein23557971
C423915TO-901317TO-901317 inhibits the reaction [Cycloheximide results in decreased expression of IL5 protein]23150660
C423915TO-901317TO-901317 results in decreased ubiquitination of and results in increased stability of IL5 protein23150660
C423915TO-901317TO-901317 results in increased expression of and results in increased secretion of IL5 protein23150660
C423915TO-901317TO-901317 results in increased expression of IL5 mRNA23150660
D014047Tolnaftate1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]11886533
D014047Tolnaftate1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]11886533
D014047TolnaftateBucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]11886533
D014047TolnaftateBucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]11886533
D014047TolnaftateColforsin inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]11886533
D014047TolnaftateColforsin inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]11886533
D014047TolnaftateTolnaftate results in decreased expression of IL5 mRNA11886533|1528482
D014047TolnaftateTolnaftate results in decreased secretion of IL5 protein11886533|1528482
D014050TolueneToluene results in increased expression of IL5 mRNA17481687
D014051Toluene 2,4-Diisocyanate"BAY 11-7085 inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"17015710
D014051Toluene 2,4-Diisocyanate"CD4 protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 mRNA]"15590890
D014051Toluene 2,4-Diisocyanate"epigallocatechin gallate inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"16516891
D014051Toluene 2,4-Diisocyanate"ICAM1 protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"17014439
D014051Toluene 2,4-Diisocyanate"pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"17015710
D014051Toluene 2,4-Diisocyanate"PPARG protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"17015710
D014051Toluene 2,4-Diisocyanate"rosiglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]"17015710
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of IL5 mRNA"15590890|1764105
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of IL5 protein"16271432|1651689
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased secretion of IL5 protein"17693426|2832985
D014051Toluene 2,4-Diisocyanate"TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased secretion of IL5 protein]"28329851
D014051Toluene 2,4-Diisocyanate"sho-seiryu-to inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 mRNA]"19050374
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of IL5 mRNA"19050374
D014118Toxins, Biological"Toxins, Biological affects the expression of IL5 mRNA"19682533
D014212TretinoinIL5 protein results in decreased activity of Tretinoin11171635
D014212TretinoinTretinoin inhibits the reaction [IL5 protein results in increased expression of IL5RA protein]10224351
D014212TretinoinTretinoin results in increased expression of IL5 mRNA17118196
D014212TretinoinTretinoin results in increased expression of IL5 protein17118196
D014222Triamcinolone Acetonide"Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]"23751068
D014241TrichloroethyleneTrichloroethylene results in decreased expression of IL5 protein16806339
D014241TrichloroethyleneTrichloroethylene results in increased methylation of IL5 gene27618143
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of IL5 protein20219652
C015559trimellitic anhydridetrimellitic anhydride results in increased secretion of IL5 protein15588915
C057693troglitazonetroglitazone results in decreased activity of IL5 protein12644321
D014635Valproic AcidValproic Acid results in increased expression of IL5 protein15794184
D001335Vehicle Emissions"[Vehicle Emissions co-treated with Amb a I protein, Ambrosia artemisiifolia] results in increased expression of IL5 mRNA"9036991
D001335Vehicle Emissions[Vehicle Emissions co-treated with Ozone] results in decreased expression of IL5 protein27058360
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL5 mRNA10075860|8765825
D001335Vehicle Emissions"RAG2 protein affects the reaction [[Vehicle Emissions co-treated with Antigens, Dermatophagoides] results in increased expression of IL5 protein]"27315767
D001335Vehicle Emissions"[Vehicle Emissions co-treated with Antigens, Dermatophagoides] results in increased expression of and results in increased secretion of IL5 protein"27315767
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of IL5 protein18307122
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL5 mRNA16007645|1697938
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL5 protein19074765
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of IL5 gene25560391
D001335Vehicle Emissions[Vehicle Emissions results in increased susceptibility to OVAL protein] which results in increased expression of IL5 mRNA24365139
D001335Vehicle Emissions[Vehicle Emissions results in increased susceptibility to OVAL protein] which results in increased expression of IL5 protein24365139|2849585
C029297vinylidene chloridevinylidene chloride results in decreased expression of IL5 protein16879906
C029297vinylidene chloridevinylidene chloride results in increased expression of IL5 protein16879906
D014810Vitamin E"[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of IL5 mRNA"16797527
C067172zopolrestat"zopolrestat inhibits the reaction [Antigens, Plant results in increased expression of IL5 mRNA]"21334316

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004713protein tyrosine kinase activity-TAS-  
GO:0005088Ras guanyl-nucleotide exchange factor activity-TAS-  
GO:0005125cytokine activity-IEA-  
GO:0005137interleukin-5 receptor binding-IEA-  
GO:0005515protein binding-IPI1495999  22153509  
GO:0008083growth factor activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000165MAPK cascade-TAS-  
GO:0006954inflammatory response-IEA-  
GO:0006955immune response-IEA-  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0018108peptidyl-tyrosine phosphorylation-IEA-  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0030890positive regulation of B cell proliferation-IEA-  
GO:0045645positive regulation of eosinophil differentiation-IEA-  
GO:0045893positive regulation of transcription, DNA-templated-IEA-  
GO:0046427positive regulation of JAK-STAT cascade-IEA-  
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation-ISS-  
GO:0051024positive regulation of immunoglobulin secretion-IEA-  
GO:0051091positive regulation of DNA-binding transcription factor activity-IEA-  
GO:0071803positive regulation of podosome assembly-IDA15220135  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IDA20041150  
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-TAS3024129  
GO:0005622intracellular-IEA-  
KEGG ID KEGG Term
hsa04060Cytokine-cytokine receptor interaction
hsa04630Jak-STAT signaling pathway
hsa04640Hematopoietic cell lineage
hsa04660T cell receptor signaling pathway
hsa04664Fc epsilon RI signaling pathway
hsa04672Intestinal immune network for IgA production
hsa05310Asthma
hsa05320Autoimmune thyroid disease
hsa05330Allograft rejection
Reactome ID Reactome Term Evidence
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-162582Signal TransductionTAS
R-HSA-168256Immune SystemTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-392451G beta:gamma signalling through PI3KgammaTAS
R-HSA-397795G-protein beta:gamma signallingTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-451927Interleukin-2 family signalingTAS
R-HSA-512988Interleukin-3, 5 and GM-CSF signalingTAS
R-HSA-5673001RAF/MAP kinase cascadeTAS
R-HSA-5683057MAPK family signaling cascadesTAS
R-HSA-5684996MAPK1/MAPK3 signalingTAS
R-HSA-912526Interleukin receptor SHC signalingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28912468Cytokine-based Predictive Models to Estimate the Probability of Chronic Periodontitis: Development of Diagnostic Nomograms. (2017 Sep 14)Tomas ISci Rep
29674199The impact of female fetal sex on preeclampsia and the maternal immune milieu. (2018 Apr)Taylor BDPregnancy Hypertens
12353662Gender differences in the allergic response of mice neonatally exposed to environmental tobacco smoke. (2002 Mar)Seymour BWDev Immunol
26986948An Interleukin 13 Polymorphism Is Associated with Symptom Severity in Adult Subjects with Ever Asthma. (2016)Accordini SPLoS One
27939488First and second trimester immune biomarkers in preeclamptic and normotensive women. (2016 Oct)Taylor BDPregnancy Hypertens