Gene: IL12B

3593
CLMF|CLMF2|IL-12B|IMD28|IMD29|NKSF|NKSF2
interleukin 12B
protein-coding
5q33.3
Ensembl:ENSG00000113302 MIM:161561 Vega:OTTHUMG00000130307 UniprotKB:P29460
NG_009618.1
PubMed|SNP Mapped
ND|AD
8   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.125e-2 (AD)  1.223e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1433048chr5:159328837 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OTOR0.454
IL20.452
RGS130.433
DEFB1150.408
OPN1MW20.403
HTR3D0.398
OR7C20.388
TAAR10.385
FAM72B0.385
FAM209B0.384

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CTSE-0.249
C10orf62-0.241
GSTM5-0.239
MYOM1-0.237
ANXA9-0.235
NFIA-0.224
RFTN2-0.224
PPARA-0.221
MFAP5-0.22
MRO-0.219

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB027635-Mercapto-2-Nitro-Benzoic AcidSmall Molecule15139-21-6ExperimentalTarget
DB05459BriakinumabBiotechDrug339308-60-0InvestigationalTarget
DB05679UstekinumabBiotechDrug815610-63-0Approved|InvestigationalTarget
DB05848humanized SMART Anti-IL-12 AntibodyBiotechDrug-InvestigationalTarget
DB06083TapinarofSmall Molecule79338-84-4InvestigationalTarget
DB05679UstekinumabBiotechDrug815610-63-0Approved|InvestigationalTarget
DB14004TildrakizumabBiotechDrug1326244-10-3ApprovedTarget
ID Drug Name Action PubMed
C4327471,1-dimethylbutyl-1-deoxy-Delta(9)-THC"1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]"15821753
C4327471,1-dimethylbutyl-1-deoxy-Delta(9)-THC"1,1-dimethylbutyl-1-deoxy-Delta(9)-THC results in decreased secretion of IL12B protein"15821753
C4327471,1-dimethylbutyl-1-deoxy-Delta(9)-THC"SR 144528 inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]"15821753
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]"19211157
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]]"15894585
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Polysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]15894585
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [nickel sulfate results in increased secretion of IL12B protein]19101624
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15821753
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of IL12B mRNA"19114083
C5704062-chloro-4'-methoxychalcone2-chloro-4'-methoxychalcone inhibits the reaction [Glucose results in increased expression of IL12B mRNA]21988173
C5704062-chloro-4'-methoxychalcone2-chloro-4'-methoxychalcone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]21988173
C4574992-chloro-5-nitrobenzanilide2-chloro-5-nitrobenzanilide inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]17475839
C0188552-tert-butylhydroquinone"2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]"25680285
C0188552-tert-butylhydroquinone"2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]"25680285
C0188552-tert-butylhydroquinone"2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]"25680285
C0188552-tert-butylhydroquinone"2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]]"25680285
C0188552-tert-butylhydroquinone"NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]"25680285
C0188552-tert-butylhydroquinone"NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]]"25680285
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in increased expression of IL12B protein26194647
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of [IL12A protein binds to IL12B protein]"29216392
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA]16365417
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]"23452621
C5239344(4-(5-nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl)-benzoic acid ethyl ester"4(4-(5-nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl)-benzoic acid ethyl ester inhibits the reaction [AGT protein modified form results in increased secretion of [IL12A protein binds to IL12B protein]]"24456201
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of IL12B mRNA"18648102
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole promotes the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]16880258
C4086904-cresol sulfate4-cresol sulfate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]26784855
C4086904-cresol sulfate4-cresol sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]26784855
C0255664-methylhistamine4-methylhistamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]11752121|1236486
C0394655-dimethylamiloride"5-dimethylamiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
C0563695-(N-methyl-N-isobutyl)amiloride"5-(N-methyl-N-isobutyl)amiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
C0476288-hydroxyeicosatetraenoic acid8-hydroxyeicosatetraenoic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16313356
D000082AcetaminophenAcetaminophen results in increased expression of IL12B mRNA22575169
D000082AcetaminophenMST1R protein affects the reaction [Acetaminophen results in increased expression of IL12B mRNA]22575169
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]21237301
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]]21237301
D000119Acetylmuramyl-Alanyl-IsoglutamineAcetylmuramyl-Alanyl-Isoglutamine analog results in increased secretion of IL12B protein15905553
D000119Acetylmuramyl-Alanyl-Isoglutamine[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]16299289
D000119Acetylmuramyl-Alanyl-Isoglutamine[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IL12B mRNA16299289
D000119Acetylmuramyl-Alanyl-Isoglutamine[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]16299289
D000119Acetylmuramyl-Alanyl-Isoglutamine[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]18490488
D000119Acetylmuramyl-Alanyl-Isoglutamine[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of IL12B protein18490488
D000119Acetylmuramyl-Alanyl-Isoglutamine[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of [IL12B protein binds to IL23A protein]18490488
D000119Acetylmuramyl-Alanyl-Isoglutamine[Acetylmuramyl-Alanyl-Isoglutamine co-treated with resiquimod co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]18490488
D000119Acetylmuramyl-Alanyl-Isoglutamine[Acetylmuramyl-Alanyl-Isoglutamine co-treated with resiquimod co-treated with IFNG protein] results in increased expression of IL12B mRNA18490488
D000119Acetylmuramyl-Alanyl-Isoglutamineresiquimod promotes the reaction [[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]18490488
D000119Acetylmuramyl-Alanyl-Isoglutamineresiquimod promotes the reaction [[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of IL12B protein]18490488
D000119Acetylmuramyl-Alanyl-IsoglutamineAcetylmuramyl-Alanyl-Isoglutamine analog results in increased secretion of IL12B protein15905553
D000119Acetylmuramyl-Alanyl-IsoglutamineAcetylmuramyl-Alanyl-Isoglutamine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]19897531
D000171AcroleinAcrolein results in increased expression of IL12B mRNA17950725
D000171AcroleinCD8A gene mutant form inhibits the reaction [Acrolein results in increased expression of IL12B mRNA]17950725
D000241AdenosineAdenosine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]11023991
D000241AdenosineAdenosine results in decreased expression of IL12B protein11023991
C022571adenosine 5'-O-(3-thiotriphosphate)adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL12B protein15944274
D000242Cyclic AMPCyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein]15843518
D000255Adenosine TriphosphateAdenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]17707769
D037361Adenylate Cyclase ToxinAdenylate Cyclase Toxin inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]14977963
D000305Adrenal Cortex HormonesAdrenal Cortex Hormones results in decreased expression of IL12B mRNA11080718
D016604Aflatoxin B1[aflatoxin B2 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
D016604Aflatoxin B1[aflatoxin G1 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
C029753aflatoxin B2[aflatoxin B2 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
C029753aflatoxin B2aflatoxin B2 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
C029753aflatoxin B2[aflatoxin G1 co-treated with aflatoxin B2] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
C027955aflatoxin G1[aflatoxin G1 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
C027955aflatoxin G1[aflatoxin G1 co-treated with aflatoxin B2] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
C103303alitretinoinalitretinoin inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]17475839
C103303alitretinoinalitretinoin results in decreased expression of [IL12A protein binds to IL12B protein]17118196
C103303alitretinoinalitretinoin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16303184
D000496AlloxanAlloxan results in decreased expression of IL12B protein16249388
C523074allylpyrocatecholallylpyrocatechol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]18602073
C545596alternaramidealternaramide inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]26620692
D000535Aluminum"[Aluminum co-treated with Copper] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA]"23690655
D000584Amiloride"Amiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
D000636Aminosalicylic AcidsAminosalicylic Acids inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11529938
D000643Ammonium ChlorideAmmonium Chloride affects the expression of IL12B mRNA16483693
C076207amthamineamthamine results in decreased expression of IL12B protein9819373
C078814anandamideanandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15748152
C078814anandamide[OMDM-1 cpd co-treated with anandamide] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15748152
C031385anthranilic acidanthranilic acid analog inhibits the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein]15799959
D039741Antigens, Dermatophagoides"Antigens, Dermatophagoides results in increased expression of IL12B mRNA"9856837
D039741Antigens, Dermatophagoides"[Parathion co-treated with Antigens, Dermatophagoides] affects the expression of IL12B protein"21864637
D000965AntimonyIL12B protein affects the susceptibility to Antimony11023473
D000967Antimony Sodium Gluconate[IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of IL12B mRNA9234779
D016718Arachidonic AcidArachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15684433
C015001arsenite"arsenite inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL12B mRNA]"25680285
C015001arsenite"arsenite inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL12B protein]"25680285
C015001arsenite"arsenite inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of [IL12B protein binds to IL12A protein]]"25680285
C015001arsenite"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]"25680285
C015001arsenite"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]"25680285
C015001arsenite"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]"25680285
C015001arsenite"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]]"25680285
C015001arsenite"NFE2L2 mutant form inhibits the reaction [arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]"25680285
C015001arsenite"NFE2L2 mutant form inhibits the reaction [arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]]"25680285
C015001arsenite"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]"25680285
C015001arsenite"NFE2L2 gene mutant form inhibits the reaction [arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]"25680285
D001241AspirinAspirin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of [IL12A protein binds to IL12B protein]]15379866
D001280AtrazineAtrazine results in decreased expression of IL12B mRNA25929836
D001374AzacitidineAzacitidine results in increased expression of IL12B mRNA20823114
D001379AzathioprineAzathioprine results in increased expression of [IL12A protein binds to IL12B protein]19584951
C416282BAY 11-7085BAY 11-7085 inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]17636246|2052589
C071435BAY u9773BAY u9773 inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]]19118273
C013407benzamil"benzamil inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
D001554BenzeneBenzene metabolite inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15894107
D001554BenzeneBenzene metabolite results in increased expression of IL12B mRNA15894107
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA17275222
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of IL12B mRNA21569818
C090535benzyloxycarbonyl-isoleucyl-glutamyl(O-tert-butyl)-alanyl-leucinalbenzyloxycarbonyl-isoleucyl-glutamyl(O-tert-butyl)-alanyl-leucinal inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]11006016
D004958Estradiol[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA20823114
D004958Estradiol"Estradiol inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]"20130130
D004958EstradiolEstradiol results in increased expression of [IL12A protein binds to IL12B protein]20130130
D004958Estradiol"[Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]"20130130
D047071beta-Glucans[beta-Glucans co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]18490488
D047071beta-Glucansbeta-Glucans results in increased expression of IL12B protein18490488
D047071beta-Glucansbeta-Glucans results in increased expression of [IL12B protein binds to IL23A protein]18490488
D047071beta-GlucansIFNG protein inhibits the reaction [beta-Glucans results in increased expression of [IL12B protein binds to IL23A protein]]18490488
D047071beta-GlucansIFNG protein promotes the reaction [beta-Glucans results in increased expression of [IL12A protein binds to IL12B protein]]18490488
D047071beta-Glucansresiquimod promotes the reaction [beta-Glucans results in increased expression of IL12B protein]18490488
D047071beta-Glucansresiquimod promotes the reaction [beta-Glucans results in increased expression of [IL12B protein binds to IL23A protein]]18490488
C002503betulinbetulin results in increased secretion of [IL12A protein binds to IL12B protein]25756279
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16330529
C006780bisphenol Abisphenol A affects the expression of IL12B mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of IL12B mRNA18569609
D001761BleomycinBleomycin results in increased expression of IL12B mRNA11350791
D001761BleomycinBleomycin results in increased expression of IL12B protein11350791
C546611brevetoxin 2brevetoxin 2 results in increased expression of IL12B mRNA20498034
C046785bryostatin 1bryostatin 1 analog results in decreased expression of IL12B mRNA15614042
C046785bryostatin 1bryostatin 1 results in increased expression of IL12B mRNA15614042
D019328Buthionine SulfoximineButhionine Sulfoximine inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]12688424
D019328Buthionine SulfoximineButhionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]19339665
D002087ButyratesButyrates results in decreased expression of [IL12A protein binds to IL12B protein]11024006
D002087ButyratesButyrates results in decreased expression of IL12B mRNA11024006
C584509C646 compound"C646 compound inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased expression of IL12B mRNA]"26718586
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of IL12B protein24583143
D019256Cadmium ChlorideCadmium Chloride results in increased methylation of IL12B promoter22457795
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA]16365417
D002110Caffeine"Caffeine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA]"26852703
D002211CapsaicinCapsaicin results in decreased expression of IL12B mRNA18533110
D002219CarbamatesCarbamates analog results in increased expression of IL12B protein19111005|1937625
D002248Carbon MonoxideCarbon Monoxide inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]16365149
D002330CarmustineCarmustine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]12688424
C043211carvedilolcarvedilol promotes the reaction [Hemagglutinins results in increased expression of [IL12A protein binds to IL12B protein]]15229385
C043211carvedilolcarvedilol promotes the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]15229385
D002713ChlorineChlorine results in increased expression of IL12B protein23146759
C007020chlorophyllinchlorophyllin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]16275627
D002772Cholera ToxinCholera Toxin results in decreased expression of [IL12A protein binds to IL12B protein]9927516
D002772Cholera ToxinCholera Toxin results in decreased expression of IL12B mRNA9927516
D002772Cholera ToxinCholera Toxin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]9927516
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IL12B mRNA20938992
C012843cinnamic aldehydecinnamic aldehyde results in decreased expression of IL12B mRNA28219650
C019304ciprofibrateciprofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15968640
C000593591coagulin-Lcoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]27568862
C000593591coagulin-Lcoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]27568862
D005576ColforsinColforsin inhibits the reaction [oxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]20512473
D005576ColforsinColforsin results in increased expression of IL12B protein10996031|1518096
D005576ColforsinColforsin results in increased expression of [IL12B protein binds to IL23A protein]15180965
D003300Copper"[Aluminum co-treated with Copper] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA]"23690655
D003300Copper[ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of IL12B mRNA15467011
D003300CopperCopper results in increased secretion of IL12B protein19635393
C423449CpG ODN 1826CpG ODN 1826 results in increased expression of IL12B protein16890772
C423449CpG ODN 1826[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] results in increased secretion of [IL12A protein binds to IL12B protein]21097750
C423449CpG ODN 1826Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]21097750
D003435Crotalid VenomsCrotalid Venoms results in increased expression of IL12B mRNA29248447
D003436Croton OilCroton Oil results in increased expression of IL12B mRNA18652873
D003436Croton OilCroton Oil results in increased expression of IL12B protein18652873
D003474CurcuminCurcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]23452621
D003474CurcuminCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]16867261
D003520CyclophosphamideCyclophosphamide affects the expression of IL12B mRNA18957084
D003520CyclophosphamideCyclophosphamide results in increased expression of IL12B mRNA15331540|2284258
D003520Cyclophosphamide[Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein]29228376
D016572CyclosporineCyclosporine inhibits the reaction [Zymosan results in increased expression of [IL12A protein binds to IL12B protein]]17312158
D003603CytotoxinsCytotoxins results in increased expression of [IL12A protein binds to IL12B protein]16291660
D003603CytotoxinsCytotoxins results in increased expression of IL12B protein16291660
C004742daidzeindaidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]21945492
C004742daidzeindaidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]21945492
C568335DCB-SLE1DCB-SLE1 inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]21677146
D013759DronabinolDronabinol inhibits the reaction [Streptozocin results in increased expression of IL12B mRNA]11357882
C007262deoxynivalenoldeoxynivalenol affects the expression of IL12B mRNA25542652
C007262deoxynivalenoldeoxynivalenol affects the expression of IL12B protein25542652
C007262deoxynivalenoldeoxynivalenol results in increased expression of IL12B mRNA9194413|9707511
C007262deoxynivalenol[Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL12B protein28935500
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]27568862
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]16880258
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]27568862
D003907DexamethasoneDexamethasone results in decreased secretion of IL12B protein28003376
D003907DexamethasoneDexamethasone results in increased expression of IL12B mRNA22842586
D003907DexamethasoneDexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]16867261
D003976DiazinonDiazinon affects the expression of IL12B protein17499902
D003976DiazinonDiazinon results in decreased expression of IL12B mRNA17499902
D003994Bucladesine[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA20823114
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of IL12B protein25051504
D002117CalcitriolCalcitriol results in decreased expression of IL12B protein15939587
D0178784,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]"11907163
D004110DiltiazemDiltiazem inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]15652234
D004110DiltiazemDiltiazem inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15652234
D004110DiltiazemDiltiazem inhibits the reaction [[NFKB1 protein binds to RELA protein] which binds to IL12B promoter]15652234
D004110DiltiazemDiltiazem results in decreased expression of IL12B mRNA15652234
D017259DimapritDimaprit inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]11752121|1236486
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of IL12B protein29024620
D004128DimethylnitrosamineZinc Oxide inhibits the reaction [Dimethylnitrosamine results in increased expression of IL12B protein]29024620
D004137DinitrochlorobenzeneDinitrochlorobenzene affects the expression of IL12B mRNA22302311
D004137DinitrochlorobenzeneDinitrochlorobenzene results in decreased methylation of IL12B gene26732893
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of IL12B mRNA10199581|1170889
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of IL12B protein18652873
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased methylation of IL12B gene26732893
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased secretion of IL12B protein10199581
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of IL12B mRNA25449201
D004139DinitrofluorobenzeneDinitrofluorobenzene results in increased expression of IL12B mRNA11708898
D004317Doxorubicin[Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein]29228376
D004365Drugs, Chinese Herbal"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]]"15894585
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of IL12B mRNA"15894585
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of IL12B protein"15894585
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]"15894585
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased secretion of IL12B protein"15894585
D004365Drugs, Chinese Herbal"helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]]"15894585
D004365Drugs, Chinese Herbal"helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of IL12B protein]"15894585
D004365Drugs, Chinese Herbal"SB 203580 inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]]"15894585
D004365Drugs, Chinese Herbal"SB 203580 inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of IL12B protein]"15894585
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of IL12B mRNA"16316537
D004391DustDust results in decreased expression of IL12B protein17805423
D004391DustDust results in increased expression of [IL12A protein binds to IL12B protein]26882889
D004391DustMYD88 gene mutant form inhibits the reaction [Dust results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D004391DustMYD88 gene mutant form inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D004391Dust[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]26882889
D004391DustPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D004391DustTLR2 gene mutant form inhibits the reaction [Dust results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D004391DustTLR4 gene mutant form inhibits the reaction [Dust results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D015118Eicosapentaenoic AcidEicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15684433
D015118Eicosapentaenoic AcidEicosapentaenoic Acid analog inhibits the reaction [sym-trinitrobenzene results in increased expression of IL12B mRNA]15890784
D015118Eicosapentaenoic Acid[Eicosapentaenoic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA22169119
D015118Eicosapentaenoic AcidEicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]22169119
D0151175,8,11,14-Eicosatetraynoic Acid"5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]"16313356
C044101endotoxin, Escherichia coli"endotoxin, Escherichia coli results in increased secretion of [IL12A protein binds to IL12B protein]"24456201
C031818enterotoxin B, staphylococcal"enterotoxin B, staphylococcal results in increased expression of and results in increased secretion of [IL12A protein binds to IL12B protein]"25556216
D004768EnterotoxinsEnterotoxins results in increased expression of IL12B mRNA16115702
D004964EstriolEstriol results in decreased expression of IL12B mRNA21317386
D000431EthanolEthanol affects the secretion of IL12B protein20624996
D000431EthanolEthanol inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]10798593
D000431EthanolEthanol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]10798593
D000431EthanolEthanol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]10798593
D000431EthanolEthanol inhibits the reaction [Poly I-C results in increased expression of IL12B protein]19500611
D005000EthionamideEthionamide results in increased expression of IL12B protein25051504
C039614ethylisopropylamiloride"ethylisopropylamiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
D005054EugenolEugenol inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]21237301
D005054EugenolEugenol inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]]21237301
D015738FamotidineFamotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]11752121|1236486
C004808farnesyl pyrophosphate"farnesyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]"15187114
D005231Fatty Acids, Unsaturated"Fatty Acids, Unsaturated inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]"15684433
D011345FenofibrateFenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15968640
C097921ferumoxtran-10ferumoxtran-10 results in decreased secretion of IL12B protein16380168
C039537FK 565[FK 565 co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]16299289
C039537FK 565[FK 565 co-treated with Lipid A] results in increased expression of IL12B mRNA16299289
C039537FK 565[FK 565 co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]16299289
D005419FlavonoidsFlavonoids results in increased expression of IL12B mRNA18035473
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of IL12B protein25051504
D005472FluorouracilFluorouracil results in decreased expression of IL12B protein15754409
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IL12B mRNA20938992
D005557FormaldehydeFormaldehyde results in increased expression of IL12B mRNA12161283
D005620Freund's AdjuvantFreund's Adjuvant promotes the reaction [Urethane results in decreased expression of IL12B mRNA]12810352
C460864FSL-1 lipoprotein, synthetic"FSL-1 lipoprotein, synthetic results in increased expression of IL12B protein"16890772
C460864FSL-1 lipoprotein, synthetic"Particulate Matter analog inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of IL12B protein]"16890772
C460864FSL-1 lipoprotein, synthetic"Vehicle Emissions analog inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of IL12B protein]"16890772
D062610Fungal PolysaccharidesFungal Polysaccharides results in increased secretion of [IL12A protein co-treated with IL12B protein]28235615
D005688Galactosamine[LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA19913045
D005688Galactosamine[LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA19913045
D005688GalactosamineGalactosamine results in increased expression of IL12B mRNA22310181
D005688Galactosaminemangiferin inhibits the reaction [Galactosamine results in increased expression of IL12B mRNA]22310181
C043055gallium arsenidegallium arsenide results in increased expression of IL12B mRNA14560044
C546771gardiquimodgardiquimod results in increased expression of IL12B mRNA28003376
C546771gardiquimodProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of IL12B mRNA]28003376
D015248GemfibrozilGemfibrozil inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15968640
D019833GenisteinGenistein inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]23452621
D005839GentamicinsGentamicins results in decreased expression of IL12B protein25051504
C002963geranylgeranyl pyrophosphate"geranylgeranyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]"15187114
C480175glucan phosphateglucan phosphate inhibits the reaction [Zymosan results in increased expression of IL12B protein]15845454
D005947Glucose2-chloro-4'-methoxychalcone inhibits the reaction [Glucose results in increased expression of IL12B mRNA]21988173
D005947GlucoseGlucose results in increased expression of IL12B mRNA21988173
C027478glucuronoxylomannanglucuronoxylomannan results in decreased secretion of [IL12A protein binds to IL12B protein]12864811
C562006glutathione-C4glutathione-C4 promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of and results in increased secretion of IL12B protein]23536773
C562006glutathione-C4glutathione-C4 promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B mRNA]23536773
D005905GlyburideGlyburide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11907163
D005905GlyburideGlyburide inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]11907163
D019695Glycyrrhizic Acid[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]11412311
D019695Glycyrrhizic Acid[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA11412311
D019695Glycyrrhizic Acid[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B protein11412311
C054591hachimijioganhachimijiogan results in decreased expression of IL12B mRNA12022442
C001329helenalin"helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]]"15894585
C001329helenalin"helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of IL12B protein]"15894585
C001329helenalinhelenalin inhibits the reaction [Polysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]15894585
C001329helenalinhelenalin inhibits the reaction [Polysaccharides results in increased secretion of IL12B protein]15894585
D006388Hemagglutininscarvedilol promotes the reaction [Hemagglutinins results in increased expression of [IL12A protein binds to IL12B protein]]15229385
D006388HemagglutininsHemagglutinins results in increased expression of [IL12A protein binds to IL12B protein]15229385
D007975Leukotriene B4Leukotriene B4 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16313356
C080043hexyl cinnamic aldehydehexyl cinnamic aldehyde affects the expression of IL12B mRNA22302311
D006632HistamineCyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein]15843518
D006632HistamineFamotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]11752121|1236486
D006632HistamineHistamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]11752121|1236486
D006632HistamineHistamine results in decreased expression of IL12B mRNA9819373
D006632HistamineHistamine results in decreased expression of IL12B protein9819373
D006632Histamine[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein15843518
D006632Histamine[Histamine results in increased activity of HRH4 protein] which results in decreased expression of IL12B protein15843518
D006632HistamineHistamine results in increased expression of IL12B protein15843518
D006632HistamineHRH2 protein affects the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]11752121
D006632HistamineHRH2 protein promotes the reaction [Histamine results in decreased expression of IL12B protein]9819373
D006632Histamine[IL12A protein binds to IL12B protein] inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]]11752121
D006632Histamine[IL12A protein binds to IL12B protein] inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]11752121
D006632HistamineRanitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]11752121
D006632HistamineRanitidine inhibits the reaction [Histamine results in decreased expression of IL12B protein]9819373
D006632HistamineU 0126 inhibits the reaction [[Histamine results in increased activity of HRH4 protein] which results in decreased expression of IL12B protein]15843518
D012701SerotoninSerotonin affects the secretion of IL12B protein15802305
D006820Hyaluronic AcidHyaluronic Acid analog results in increased secretion of IL12B protein9278343
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [N-bromotaurine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]15723204
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of [IL12A protein binds to IL12B protein]16249388
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of IL12B protein16249388
D006861Hydrogen PeroxideTrifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IL12B protein]16249388
C031927hydroquinonehydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15894107|1746419
C031927hydroquinonehydroquinone results in increased expression of IL12B mRNA15894107
C436346I-152 compoundI-152 compound inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of and results in increased secretion of IL12B protein]23536773
C436346I-152 compoundI-152 compound inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B mRNA]23536773
C038366ibudilastibudilast results in decreased expression of [IL12A protein binds to IL12B protein]14664469
C038366ibudilastibudilast results in decreased expression of IL12B mRNA14664469
C490483icilinicilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein]23596210
C056493imiquimod[imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]21097750
C056493imiquimodTetrachlorodibenzodioxin inhibits the reaction [[imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]21097750
D007213IndomethacinIndomethacin results in increased expression of [IL12A protein binds to IL12B protein]11703811
D007213IndomethacinIndomethacin results in increased expression of IL12B protein25051504
D007501IronIron affects the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein]15799959
D007502Iron Chelating AgentsIron Chelating Agents analog inhibits the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein]15799959
D017953IsocyanatesIsocyanates analog results in increased expression of IL12B protein19111005
D007538IsoniazidIsoniazid results in increased secretion of IL12B protein28444390
D007545IsoproterenolIsoproterenol results in increased expression of IL12B protein24286936
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]25725100
C063587juzentaihotojuzentaihoto promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
C103873KRN 7000KRN 7000 results in increased expression of IL12B protein15867097
D007840LatexLatex analog results in increased expression of IL12B mRNA24768652
D007854LeadLead results in increased expression of and results in increased secretion of [IL12A protein binds to IL12B protein]28973681
C467567lenalidomidelenalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of IL12B mRNA]16510725
D008050Lipid A[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]16299289
D008050Lipid A[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of IL12B mRNA16299289
D008050Lipid A[FK 565 co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein]16299289
D008050Lipid A[FK 565 co-treated with Lipid A] results in increased expression of IL12B mRNA16299289
D008050Lipid ALipid A results in increased expression of [IL12A protein binds to IL12B protein]16299289
D008050Lipid ALipid A results in increased expression of IL12B mRNA16299289
C050016lipoarabinomannanlipoarabinomannan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]16263713
C014643lipopeptidophosphoglycan[lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of IL12B protein15910421
C014643lipopeptidophosphoglycan[lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein15910421
C482199lipopolysaccharide, E coli O55-B5"2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]"25680285
C482199lipopolysaccharide, E coli O55-B5"2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]"25680285
C482199lipopolysaccharide, E coli O55-B5"2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]"25680285
C482199lipopolysaccharide, E coli O55-B5"2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]]"25680285
C482199lipopolysaccharide, E coli O55-B5"arsenite inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL12B mRNA]"25680285
C482199lipopolysaccharide, E coli O55-B5"arsenite inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL12B protein]"25680285
C482199lipopolysaccharide, E coli O55-B5"arsenite inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of [IL12B protein binds to IL12A protein]]"25680285
C482199lipopolysaccharide, E coli O55-B5"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]"25680285
C482199lipopolysaccharide, E coli O55-B5"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]"25680285
C482199lipopolysaccharide, E coli O55-B5"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]"25680285
C482199lipopolysaccharide, E coli O55-B5"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]]"25680285
C482199lipopolysaccharide, E coli O55-B5"[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL12B mRNA"25680285
C482199lipopolysaccharide, E coli O55-B5"[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL12B protein"25680285
C482199lipopolysaccharide, E coli O55-B5"[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of [IL12B protein binds to IL12A protein]"25680285
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein"23266719
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA"25673294|2568028
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein"25673294
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein"25680285
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]"25680285
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL23A protein binds to IL12B protein]"25680285
C482199lipopolysaccharide, E coli O55-B5"Nanotubes, Carbon promotes the reaction [[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein]"23266719
C482199lipopolysaccharide, E coli O55-B5"NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]"25680285
C482199lipopolysaccharide, E coli O55-B5"NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]]"25680285
C482199lipopolysaccharide, E coli O55-B5"NFE2L2 mutant form inhibits the reaction [arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]"25680285
C482199lipopolysaccharide, E coli O55-B5"NFE2L2 mutant form inhibits the reaction [arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of [IL12B protein binds to IL12A protein]]]"25680285
C482199lipopolysaccharide, E coli O55-B5"5-dimethylamiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
C482199lipopolysaccharide, E coli O55-B5"5-(N-methyl-N-isobutyl)amiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
C482199lipopolysaccharide, E coli O55-B5"Amiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
C482199lipopolysaccharide, E coli O55-B5"arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]"25680285
C482199lipopolysaccharide, E coli O55-B5"benzamil inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
C482199lipopolysaccharide, E coli O55-B5"ethylisopropylamiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein]"11420121
C482199lipopolysaccharide, E coli O55-B5"farnesyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]"15187114
C482199lipopolysaccharide, E coli O55-B5"geranylgeranyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]"15187114
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased expression of IL12B mRNA"11420121
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein"11420121
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA"15187114|2568028
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein"15187114|1987866
C482199lipopolysaccharide, E coli O55-B5"Mevalonic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]"15187114
C482199lipopolysaccharide, E coli O55-B5"NFE2L2 gene mutant form inhibits the reaction [arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]]"25680285
C482199lipopolysaccharide, E coli O55-B5"Simvastatin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]"15187114
C482199lipopolysaccharide, E coli O55-B5"Simvastatin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]"15187114
C440499lipopolysaccharide, Escherichia coli O111 B4"[Aluminum co-treated with Copper] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA]"23690655
C440499lipopolysaccharide, Escherichia coli O111 B4"C646 compound inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased expression of IL12B mRNA]"26718586
C440499lipopolysaccharide, Escherichia coli O111 B4"Caffeine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA]"26852703
C440499lipopolysaccharide, Escherichia coli O111 B4"EIF2AK2 gene mutant form inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA]"10944112
C440499lipopolysaccharide, Escherichia coli O111 B4"EIF2AK2 gene mutant form inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B protein]"10944112
C440499lipopolysaccharide, Escherichia coli O111 B4"[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased expression of IL12B mRNA"26718586
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA"23690655|2685270
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B protein"10944112
D008070Lipopolysaccharides"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]"19211157
D008070Lipopolysaccharides2-chloro-5-nitrobenzanilide inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]17475839
D008070Lipopolysaccharides8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15802305
D008070Lipopolysaccharides[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]16299289
D008070LipopolysaccharidesAdenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]17707769
D008070Lipopolysaccharidesalitretinoin inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]17475839
D008070LipopolysaccharidesArachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15684433
D008070LipopolysaccharidesAspirin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of [IL12A protein binds to IL12B protein]]15379866
D008070Lipopolysaccharidescarvedilol promotes the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]15229385
D008070Lipopolysaccharidescoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]27568862
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]27568862
D008070LipopolysaccharidesDiltiazem inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]15652234
D008070LipopolysaccharidesDiltiazem inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15652234
D008070LipopolysaccharidesDinoprostone inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]11369638
D008070LipopolysaccharidesDinoprostone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]11369638
D008070LipopolysaccharidesEicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15684433
D008070Lipopolysaccharides"Fatty Acids, Unsaturated inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]"15684433
D008070Lipopolysaccharides[FK 565 co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]16299289
D008070LipopolysaccharidesHTR4 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15802305
D008070LipopolysaccharidesHTR7 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15802305
D008070LipopolysaccharidesIL10 protein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]9637507
D008070Lipopolysaccharides(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]25725100
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of [IL12A protein binds to IL12B protein]15379866
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL12B protein]18490488
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]18490488
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]10651989|1522938
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL12B mRNA11717198|1247061
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL12B protein15914193|1689077
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]11369638|1747583
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of IL12B protein11369638|1513531
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of [IL12B protein binds to IL12A protein]15135313
D008070LipopolysaccharidesNFE2L2 protein affects the reaction [Particulate Matter analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]16890772
D008070LipopolysaccharidesNFE2L2 protein affects the reaction [sulforafan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]16890772
D008070LipopolysaccharidesNFE2L2 protein affects the reaction [Vehicle Emissions analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]16890772
D008070LipopolysaccharidesParticulate Matter analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]16890772
D008070Lipopolysaccharidesphenanthridone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]17579050
D008070Lipopolysaccharidesresveratrol promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15135313
D008070Lipopolysaccharidesresveratrol promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12B protein co-treated with IL12A protein]]15135313
D008070Lipopolysaccharides[Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]9722937
D008070LipopolysaccharidesRibavirin promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]9722937
D008070Lipopolysaccharidesrosiglitazone inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]17475839
D008070Lipopolysaccharidessulforafan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]16890772
D008070Lipopolysaccharides"thieno(2,3-c)isoquinolin-5-one inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]"17579050
D008070LipopolysaccharidesTretinoin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]17253143
D008070Lipopolysaccharidestrichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]12470611
D008070LipopolysaccharidesVehicle Emissions analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]16890772
D008070Lipopolysaccharides"1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]"15821753
D008070Lipopolysaccharides2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15821753
D008070Lipopolysaccharides2-chloro-4'-methoxychalcone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]21988173
D008070Lipopolysaccharides3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
D008070Lipopolysaccharides"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]"11907163
D008070Lipopolysaccharides4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole promotes the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]16880258
D008070Lipopolysaccharides4-cresol sulfate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]26784855
D008070Lipopolysaccharides4-cresol sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]26784855
D008070Lipopolysaccharides"5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]"16313356
D008070Lipopolysaccharides8-hydroxyeicosatetraenoic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16313356
D008070LipopolysaccharidesAcetylmuramyl-Alanyl-Isoglutamine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]19897531
D008070LipopolysaccharidesAdenosine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]11023991
D008070LipopolysaccharidesAdenylate Cyclase Toxin inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]14977963
D008070Lipopolysaccharides[aflatoxin B2 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
D008070Lipopolysaccharidesaflatoxin B2 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
D008070Lipopolysaccharides[aflatoxin G1 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
D008070Lipopolysaccharides[aflatoxin G1 co-treated with aflatoxin B2] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]22445859
D008070Lipopolysaccharidesalitretinoin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16303184
D008070Lipopolysaccharidesallylpyrocatechol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]18602073
D008070Lipopolysaccharidesalternaramide inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]26620692
D008070LipopolysaccharidesAminosalicylic Acids inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11529938
D008070Lipopolysaccharidesanandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15748152
D008070LipopolysaccharidesBenzene metabolite inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15894107
D008070Lipopolysaccharides[Benzo(a)pyrene co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA17275222
D008070Lipopolysaccharidesbenzyloxycarbonyl-isoleucyl-glutamyl(O-tert-butyl)-alanyl-leucinal inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]11006016
D008070Lipopolysaccharidesbisindolylmaleimide I inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16330529
D008070LipopolysaccharidesButhionine Sulfoximine inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]12688424
D008070LipopolysaccharidesButhionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]19339665
D008070LipopolysaccharidesCarbon Monoxide inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]16365149
D008070LipopolysaccharidesCarmustine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]12688424
D008070LipopolysaccharidesCD14 protein affects the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]11123339
D008070Lipopolysaccharideschlorophyllin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]16275627
D008070LipopolysaccharidesCholera Toxin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]9927516
D008070Lipopolysaccharidesciprofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15968640
D008070Lipopolysaccharidescoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]27568862
D008070LipopolysaccharidesColforsin inhibits the reaction [oxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]20512473
D008070Lipopolysaccharidesdaidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]21945492
D008070Lipopolysaccharidesdaidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]21945492
D008070LipopolysaccharidesDCB-SLE1 inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]21677146
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]16880258
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]27568862
D008070Lipopolysaccharides[Eicosapentaenoic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA22169119
D008070LipopolysaccharidesEicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]22169119
D008070LipopolysaccharidesEthanol inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]10798593
D008070LipopolysaccharidesEthanol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]10798593
D008070LipopolysaccharidesEthanol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]10798593
D008070LipopolysaccharidesFenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15968640
D008070LipopolysaccharidesGemfibrozil inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15968640
D008070Lipopolysaccharidesglutathione-C4 promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of and results in increased secretion of IL12B protein]23536773
D008070Lipopolysaccharidesglutathione-C4 promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B mRNA]23536773
D008070LipopolysaccharidesGlyburide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11907163
D008070LipopolysaccharidesGlyburide inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]11907163
D008070Lipopolysaccharides[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]11412311
D008070Lipopolysaccharides[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA11412311
D008070Lipopolysaccharides[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B protein11412311
D008070LipopolysaccharidesHydrogen Peroxide inhibits the reaction [N-bromotaurine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]15723204
D008070Lipopolysaccharideshydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15894107|1746419
D008070LipopolysaccharidesI-152 compound inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of and results in increased secretion of IL12B protein]23536773
D008070LipopolysaccharidesI-152 compound inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B mRNA]23536773
D008070LipopolysaccharidesIFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]10415056
D008070LipopolysaccharidesIL10 protein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15821753
D008070LipopolysaccharidesIL12B protein affects the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]10415056
D008070LipopolysaccharidesIL6 protein affects the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15804595
D008070LipopolysaccharidesIRF1 protein affects the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]]10415056
D008070LipopolysaccharidesIRF1 protein affects the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]10415056
D008070LipopolysaccharidesIRF1 protein affects the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]10415056
D008070LipopolysaccharidesIRF1 protein affects the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]10415056
D008070LipopolysaccharidesIRF2 protein affects the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]]10415056
D008070LipopolysaccharidesIRF2 protein affects the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]10415056
D008070LipopolysaccharidesIRF2 protein affects the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]10415056
D008070LipopolysaccharidesIRF2 protein affects the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]10415056
D008070LipopolysaccharidesITGAM protein affects the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]11123339
D008070Lipopolysaccharidesjuzentaihoto promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
D008070LipopolysaccharidesLeukotriene B4 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16313356
D008070Lipopolysaccharideslipoarabinomannan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]16263713
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] results in increased secretion of [IL12A protein binds to IL12B protein]21097750
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL12B protein28935500
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of and results in increased secretion of IL12B protein23536773
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B mRNA23536773
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein11529938|1190716
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12B protein binds to IL12A protein]11529938
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of IL12B mRNA21977998
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with ochratoxin A] results in increased expression of IL12B protein28935500
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Zymosan] results in increased expression of IL12B mRNA15213630
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]10798593|1902077
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL12B mRNA10415056|1079859
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of IL12B protein10798593|1190716
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]10415056|1112333
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of IL12B protein10415056|1102399
D008070LipopolysaccharidesLithium inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]19159680
D008070LipopolysaccharidesLuteolin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]19426678
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15933225|2405697
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]15933225
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16321413|1933966
D008070Lipopolysaccharidesmethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15933225
D008070Lipopolysaccharides[Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]16321413
D008070LipopolysaccharidesN-bromotaurine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15723204
D008070LipopolysaccharidesN-chlorotaurine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15723204
D008070Lipopolysaccharides[OMDM-1 cpd co-treated with anandamide] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15748152
D008070LipopolysaccharidesOMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15748152
D008070Lipopolysaccharidesoxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]20512473
D008070Lipopolysaccharidesoxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]20512473
D008070Lipopolysaccharides[Ozone co-treated with Lipopolysaccharides] results in increased expression of IL12B protein18929643
D008070LipopolysaccharidesParticulate Matter inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]19805405
D008070Lipopolysaccharidespirinixic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15968640
D008070LipopolysaccharidesPlant Extracts inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]21989142
D008070LipopolysaccharidesPolymyxin B inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]9278343
D008070LipopolysaccharidesPRKCD protein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16330529
D008070LipopolysaccharidesPRKCE protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16330529
D008070Lipopolysaccharidesprocyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]22169119
D008070LipopolysaccharidesProgesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of IL12B mRNA]21977998
D008070LipopolysaccharidesProgesterone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]21977998
D008070Lipopolysaccharidespyrazolanthrone promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
D008070Lipopolysaccharidespyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
D008070LipopolysaccharidesQuercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]22185406
D008070Lipopolysaccharides[resiquimod co-treated with Lipopolysaccharides] results in increased secretion of [IL12A protein binds to IL12B protein]15851485
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]14996416
D008070Lipopolysaccharidesrottlerin promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16330529
D008070LipopolysaccharidesSB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]11006016
D008070LipopolysaccharidesSB 203580 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
D008070Lipopolysaccharides"SR 144528 inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]"15821753
D008070LipopolysaccharidesSulfapyridine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11529938
D008070LipopolysaccharidesSulfasalazine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11529938
D008070LipopolysaccharidesSulfasalazine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12B protein binds to IL12A protein]]11529938
D008070LipopolysaccharidesSulfobromophthalein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11907163
D008070Lipopolysaccharidesterameprocol affects the reaction [Lipopolysaccharides results in increased expression of IL12B protein]19133137
D008070LipopolysaccharidesTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]21097750
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]11123339
D008070Lipopolysaccharidestobacco tar inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15894107
D008070Lipopolysaccharides"tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]"22185406
D008070LipopolysaccharidesU 0126 promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
D008070LipopolysaccharidesVehicle Emissions inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]19805405
D008070LipopolysaccharidesIFNG protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15135313
D008070LipopolysaccharidesIFNG protein promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12B protein co-treated with IL12A protein]]15135313
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]16321413
D008070Lipopolysaccharidesresveratrol inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]15135313
D008070Lipopolysaccharidesresveratrol inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12B protein co-treated with IL12A protein]]]15135313
D008094LithiumLithium inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]19159680
C068562loxoribineloxoribine results in increased expression of [IL12A protein binds to IL12B protein]15777634
C068562loxoribineU 0126 promotes the reaction [loxoribine results in increased expression of [IL12A protein binds to IL12B protein]]15777634
D017998Leukotriene D4BAY u9773 inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]]19118273
D017998Leukotriene D4Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]19118273
D017998Leukotriene D4montelukast inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]]19118273
D017998Leukotriene D4zileuton inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]]19118273
C480546lupanelupane results in increased secretion of [IL12A protein binds to IL12B protein]16388738
D047311LuteolinLuteolin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]19426678
D047311LuteolinLuteolin inhibits the reaction [Poly I-C results in increased expression of IL12B mRNA]19426678
C025340manganese chloridemanganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]28539244
C025340manganese chloridemanganese chloride results in increased expression of [IL12A protein binds to IL12B protein]28539244
C025340manganese chloridemanganese chloride results in increased expression of IL12B mRNA28539244
C013592mangiferinmangiferin inhibits the reaction [Galactosamine results in increased expression of IL12B mRNA]22310181
D008466MechlorethamineMechlorethamine results in increased expression of IL12B mRNA28184907
D008466MechlorethamineValproic Acid inhibits the reaction [Mechlorethamine results in increased expression of IL12B mRNA]28184907
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA20823114
C033266Menhaden oilMenhaden oil results in decreased expression of [IL12A protein binds to IL12B protein]10065739
C033266Menhaden oilMenhaden oil results in decreased expression of IL12B mRNA10065739
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of IL12B protein21984480
D008627Mercuric ChlorideMercuric Chloride results in increased expression of [IL12A protein binds to IL12B protein]21984480
D008701MethapyrileneMethapyrilene results in increased expression of IL12B protein25051504
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IL12B mRNA20938992
D008731MethoxychlorMethoxychlor results in increased expression of IL12B mRNA22842586
C008435methyldithiocarbamateButhionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]19339665
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15933225|2405697
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]15933225
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16321413|1933966
C008435methyldithiocarbamate[Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]16321413
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]16321413
C005227methyl isothiocyanatemethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15933225
D008798Mevalonic Acid"Mevalonic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]"15187114
D015735Mifepristone[Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]16321413
C093875montelukastmontelukast inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]]19118273
D009020MorphineMorphine affects the expression of [IL12A protein binds to IL12B protein]16299287
D009020MorphineMorphine affects the expression of IL12B protein16299287
D009151Mustard GasMustard Gas results in increased expression of IL12B mRNA15674843
C084956N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosineN(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]16116186
C084956N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosinePertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]16116186
C084956N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosinewortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]16116186
D009248Nadolol[Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]16321413
D037742Nanotubes, Carbon"Nanotubes, Carbon inhibits the reaction [TLR5 protein results in increased secretion of IL12B protein]"23266719
D037742Nanotubes, Carbon"Nanotubes, Carbon promotes the reaction [[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein]"23266719
D037742Nanotubes, Carbon"[[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein"23266719
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of IL12B mRNA"23845593
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of IL12B mRNA"25554681
C052954N-bromotaurineHydrogen Peroxide inhibits the reaction [N-bromotaurine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]15723204
C052954N-bromotaurineN-bromotaurine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15723204
C043410N-chlorotaurineN-chlorotaurine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15723204
D009532NickelNickel results in increased expression of IL12B mRNA24768652
C029938nickel sulfate2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [nickel sulfate results in increased secretion of IL12B protein]19101624
C029938nickel sulfateBAY 11-7085 inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]17636246|2052589
C029938nickel sulfatenickel sulfate affects the expression of IL12B mRNA18202158
C029938nickel sulfatenickel sulfate results in increased expression of IL12B mRNA25673294
C029938nickel sulfatenickel sulfate results in increased expression of IL12B protein25673294
C029938nickel sulfatenickel sulfate results in increased secretion of IL12B protein17636246|1910162
C029938nickel sulfatepyrazolanthrone inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]19101624
C029938nickel sulfateSB 203580 inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]19101624|2052589
C029938nickel sulfate[IFNG protein co-treated with nickel sulfate] results in increased secretion of IL12B protein20525893
C029938nickel sulfateIFNG protein promotes the reaction [nickel sulfate results in increased secretion of IL12B protein]20525893
C029938nickel sulfateIRF1 mRNA affects the reaction [[IFNG protein co-treated with nickel sulfate] results in increased secretion of IL12B protein]20525893
D009538NicotineAcetylcysteine inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]21237301
D009538NicotineAcetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]]21237301
D009538NicotineEugenol inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]21237301
D009538NicotineEugenol inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]]21237301
D009538NicotineNicotine results in increased expression of IL12B mRNA21237301
D009538NicotineNicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]21237301
D009569Nitric OxideNitric Oxide results in decreased expression of IL12B protein13678430
D020030Nitric Oxide DonorsNitric Oxide Donors results in decreased expression of IL12B protein13678430
D0151124-Nitroquinoline-1-oxide4-Nitroquinoline-1-oxide results in decreased expression of IL12B mRNA22561872
D0151124-Nitroquinoline-1-oxide4-Nitroquinoline-1-oxide results in increased expression of IL12B mRNA22561872
D026422S-NitrosoglutathioneS-Nitrosoglutathione results in decreased expression of IL12B protein13678430
C025589ochratoxin A[Lipopolysaccharides co-treated with ochratoxin A] results in increased expression of IL12B protein28935500
D0173718-Hydroxy-2-(di-n-propylamino)tetralin8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15802305
C474344OMDM-1 cpd[OMDM-1 cpd co-treated with anandamide] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15748152
C474344OMDM-1 cpdOMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15748152
D015525Fatty Acids, Omega-3"Fatty Acids, Omega-3 results in decreased expression of [IL12A protein binds to IL12B protein]"10065739
D015525Fatty Acids, Omega-3"Fatty Acids, Omega-3 results in decreased expression of IL12B mRNA"10065739
D010047OvalbuminMYD88 gene mutant form inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D010047Ovalbumin[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]26882889
D010047OvalbuminPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D010081OxazoloneOxazolone results in increased expression of IL12B mRNA11379042|1170889
D010081OxazoloneOxazolone results in increased expression of IL12B protein18652873
C029341oxophenylarsineColforsin inhibits the reaction [oxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]20512473
C029341oxophenylarsineoxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]20512473
C029341oxophenylarsineoxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]20512473
D010100Oxygen"3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]"23452621
D010100OxygenCurcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]23452621
D010100OxygenGenistein inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]23452621
D010100OxygenOxygen deficiency results in increased expression of IL12B mRNA23452621
D010100OxygenPlant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]23452621
D010100Oxygenresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]23452621
D010100OxygenOxygen deficiency results in decreased expression of IL12B mRNA24205000
D010126Ozone[Vehicle Emissions co-treated with Ozone] results in decreased expression of [IL12A protein binds to IL12B protein]27058360
D010126Ozone[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of IL12B protein27472835
D010126Ozone[Ozone co-treated with Lipopolysaccharides] results in increased expression of IL12B protein18929643
D017239PaclitaxelCD14 protein affects the reaction [Paclitaxel results in increased expression of IL12B mRNA]11123339
D017239PaclitaxelITGAM protein affects the reaction [Paclitaxel results in increased secretion of [IL12A protein binds to IL12B protein]]11123339
D017239PaclitaxelPaclitaxel results in increased expression of IL12B mRNA11123339
D017239PaclitaxelPaclitaxel results in increased secretion of [IL12A protein binds to IL12B protein]11123339
D017239PaclitaxelTLR4 protein affects the reaction [Paclitaxel results in increased expression of IL12B mRNA]11123339
C508075Pam(3)CSK(4) peptide[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]18490488
C508075Pam(3)CSK(4) peptide[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of IL12B protein18490488
C508075Pam(3)CSK(4) peptide[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of [IL12B protein binds to IL23A protein]18490488
C508075Pam(3)CSK(4) peptideresiquimod promotes the reaction [[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]18490488
C508075Pam(3)CSK(4) peptideresiquimod promotes the reaction [[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of IL12B protein]18490488
C508075Pam(3)CSK(4) peptidePam(3)CSK(4) peptide results in increased expression of IL12B protein15187114
C508075Pam(3)CSK(4) peptideSimvastatin promotes the reaction [Pam(3)CSK(4) peptide results in increased expression of IL12B protein]15187114
D010278Parathion"[Parathion co-treated with Antigens, Dermatophagoides] affects the expression of IL12B protein"21864637
D010278ParathionParathion results in increased expression of IL12B mRNA22842586
C002669parthenolideparthenolide results in decreased expression of IL12B mRNA16921510
D052638Particulate MatterNFE2L2 protein affects the reaction [Particulate Matter analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]16890772
D052638Particulate Matter"Particulate Matter analog inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of IL12B protein]"16890772
D052638Particulate MatterParticulate Matter analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]16890772
D052638Particulate MatterParticulate Matter analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]16890772
D052638Particulate MatterParticulate Matter inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]19805405
D052638Particulate MatterParticulate Matter results in decreased expression of IL12B mRNA11936774|1221721
D052638Particulate MatterParticulate Matter results in decreased expression of IL12B protein11936774
D052638Particulate MatterParticulate Matter results in increased expression of IL12B mRNA14594659|2363800
D052638Particulate MatterParticulate Matter results in increased expression of IL12B mRNA24216475
C008776pelargonic acidpelargonic acid affects the expression of IL12B mRNA22302311
C008776pelargonic acidpelargonic acid results in increased expression of IL12B mRNA11379042|1865287
C008776pelargonic acidpelargonic acid results in increased expression of IL12B protein18652873
D010457PeptidoglycanPeptidoglycan results in increased expression of IL12B mRNA15860229
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of IL12B mRNA19162173
D010476PerfumePerfume results in increased expression of IL12B mRNA24768652
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [C5 protein results in decreased expression of [IL12A protein binds to IL12B protein]]16116186
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]16116186
D015232DinoprostoneDinoprostone inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]11369638
D015232DinoprostoneDinoprostone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]11369638
D015232DinoprostoneDinoprostone results in increased expression of IL12B mRNA11369638
D015232DinoprostoneDinoprostone results in increased expression of IL12B protein16303787
D015232DinoprostoneDinoprostone results in increased secretion of IL12B protein11369638
D015232Dinoprostone[TNF protein co-treated with IL1B protein co-treated with Dinoprostone] results in increased expression of IL12B protein10614771
D015232DinoprostoneCSF2 protein promotes the reaction [Dinoprostone results in increased expression of [IL12B protein binds to IL23A protein]]15180965
D015232DinoprostoneDinoprostone results in increased expression of IL12B protein15180965
D015232DinoprostoneDinoprostone results in increased expression of [IL12B protein binds to IL23A protein]15180965
C040601phenanthridonephenanthridone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]17579050
D015240Phorbol 12,13-Dibutyrate"Phorbol 12,13-Dibutyrate results in increased expression of IL12B mRNA"15516327
D010726Phosphodiesterase InhibitorsPhosphodiesterase Inhibitors results in decreased expression of [IL12A protein binds to IL12B protein]14664469
D010726Phosphodiesterase InhibitorsPhosphodiesterase Inhibitors results in decreased expression of IL12B mRNA14664469
D009764o-Phthalaldehydeo-Phthalaldehyde affects the expression of IL12B mRNA22302311
D010862PilocarpinePilocarpine results in increased expression of IL12B mRNA15193289
C006253pirinixic acid[Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein17371993
C006253pirinixic acidpirinixic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15968640
C006253pirinixic acidpirinixic acid results in decreased expression of IL12B protein20131406
C006253pirinixic acidPPARA protein affects the reaction [[Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein]17371993
C006253pirinixic acidpirinixic acid results in increased expression of IL12B mRNA19162173
D010936Plant ExtractsPlant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]23452621
D010936Plant ExtractsPlant Extracts inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]21989142
D010936Plant ExtractsPlant Extracts results in increased expression of IL12B mRNA23108216|2324645
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of IL12B protein29175452
D011070Poly I-CParticulate Matter analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]16890772
D011070Poly I-C"[[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein"23266719
D011070Poly I-CPoly I-C results in increased expression of IL12B protein16890772
D011070Poly I-CVehicle Emissions analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]16890772
D011070Poly I-CEthanol inhibits the reaction [Poly I-C results in increased expression of IL12B protein]19500611
D011070Poly I-CLuteolin inhibits the reaction [Poly I-C results in increased expression of IL12B mRNA]19426678
D011070Poly I-CPoly I-C results in increased expression of IL12B mRNA19426678
D011070Poly I-CPoly I-C results in increased expression of IL12B protein19500611
D011112Polymyxin BPolymyxin B inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]9278343
D011112Polymyxin BPolymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D059808PolyphenolsPolyphenols results in decreased expression of IL12B mRNA16293270
D011134Polysaccharides2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Polysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]15894585
D011134Polysaccharideshelenalin inhibits the reaction [Polysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]15894585
D011134Polysaccharideshelenalin inhibits the reaction [Polysaccharides results in increased secretion of IL12B protein]15894585
D011134PolysaccharidesPolysaccharides results in increased expression of IL12B mRNA15894585
D011134PolysaccharidesPolysaccharides results in increased expression of IL12B protein15894585
D011134PolysaccharidesPolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]15894585
D011134PolysaccharidesPolysaccharides results in increased secretion of IL12B protein15894585
D011134PolysaccharidesSB 203580 inhibits the reaction [Polysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]15894585
D011134PolysaccharidesSB 203580 inhibits the reaction [Polysaccharides results in increased secretion of IL12B protein]15894585
D011134PolysaccharidesPolysaccharides results in increased expression of IL12B mRNA23108216|2324645
D011239PrednisolonePrednisolone results in decreased secretion of IL12B protein28003376
D011241PrednisonePrednisone results in increased expression of [IL12A protein binds to IL12B protein]19584951
C479581procyanidin B3procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]22169119
D011374ProgesteroneProgesterone results in increased expression of IL12B mRNA23034158
D011374Progesterone"[Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]"20130130
D011374Progesterone"Progesterone inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]"20130130
D011374ProgesteroneProgesterone results in increased expression of [IL12A protein binds to IL12B protein]20130130
D011374ProgesteroneProgesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of IL12B mRNA]21977998
D011374ProgesteroneProgesterone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]21977998
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of IL12B mRNA]28003376
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors results in decreased secretion of IL12B protein28003376
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]19101624
C432165pyrazolanthronepyrazolanthrone promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
D011794QuercetinQuercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]22185406
D011794QuercetinQuercetin results in decreased expression of IL12B mRNA22185406
D011899RanitidineRanitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]11752121
D011899RanitidineRanitidine inhibits the reaction [Histamine results in decreased expression of IL12B protein]9819373
C402365resiquimod[Acetylmuramyl-Alanyl-Isoglutamine co-treated with resiquimod co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]18490488
C402365resiquimod[Acetylmuramyl-Alanyl-Isoglutamine co-treated with resiquimod co-treated with IFNG protein] results in increased expression of IL12B mRNA18490488
C402365resiquimod[beta-Glucans co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]18490488
C402365resiquimodIFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]]18490488
C402365resiquimodIFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of IL12B protein]18490488
C402365resiquimodIFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]]18490488
C402365resiquimod[Lipopolysaccharides co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL12B protein]18490488
C402365resiquimod[Lipopolysaccharides co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]18490488
C402365resiquimodresiquimod promotes the reaction [[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]18490488
C402365resiquimodresiquimod promotes the reaction [[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of IL12B protein]18490488
C402365resiquimodresiquimod promotes the reaction [beta-Glucans results in increased expression of IL12B protein]18490488
C402365resiquimodresiquimod promotes the reaction [beta-Glucans results in increased expression of [IL12B protein binds to IL23A protein]]18490488
C402365resiquimodresiquimod results in increased expression of IL12B protein18490488
C402365resiquimod[Zymosan co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]18490488
C402365resiquimod[Zymosan co-treated with resiquimod] results in increased expression of IL12B protein18490488
C402365resiquimod[Zymosan co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]18490488
C402365resiquimod[resiquimod co-treated with Lipopolysaccharides] results in increased secretion of [IL12A protein binds to IL12B protein]15851485
C402365resiquimodresiquimod results in increased expression of IL12B protein15187114
C402365resiquimodSimvastatin promotes the reaction [resiquimod results in increased expression of IL12B protein]15187114
C059514resveratrolresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]23452621
C059514resveratrolresveratrol promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15135313
C059514resveratrolresveratrol promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12B protein co-treated with IL12A protein]]15135313
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]14996416
C059514resveratrolresveratrol inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]15135313
C059514resveratrolresveratrol inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12B protein co-treated with IL12A protein]]]15135313
D012254Ribavirin[Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]9722937
D012254RibavirinRibavirin promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]9722937
C084904Ro 41-5253Ro 41-5253 inhibits the reaction [Tretinoin results in decreased secretion of [IL12A protein binds to IL12B protein]]16872382
C089730rosiglitazonerosiglitazone inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]17475839
C085746rottlerinrottlerin promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]16330529
C099445S 28463S 28463 results in decreased expression of [IL12A protein binds to IL12B protein]16361354
C121329sanglifehrin Asanglifehrin A results in decreased expression of [IL12A protein binds to IL12B protein]12847216
C121329sanglifehrin Asanglifehrin A results in decreased expression of IL12B mRNA12847216
C093642SB 203580"SB 203580 inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]]"15894585
C093642SB 203580"SB 203580 inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of IL12B protein]"15894585
C093642SB 203580SB 203580 inhibits the reaction [[IL12A protein binds to IL12B protein] which results in increased expression of IFNG protein]10952721
C093642SB 203580SB 203580 inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]19101624|2052589
C093642SB 203580SB 203580 inhibits the reaction [Polysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]15894585
C093642SB 203580SB 203580 inhibits the reaction [Polysaccharides results in increased secretion of IL12B protein]15894585
C093642SB 203580SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]11006016
C093642SB 203580SB 203580 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of IL12B protein"17200189|1840367
D017632Asbestos, Serpentine"PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL12B protein]"17200189
D017632Asbestos, Serpentine"SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL12B protein]"21514415
D012822Silicon DioxideIL12A gene mutant form promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of IL12B protein]12193738
D012822Silicon DioxideIL12B gene mutant form results in decreased susceptibility to Silicon Dioxide12193738
D012822Silicon DioxideIL12B protein affects the susceptibility to Silicon Dioxide12193738
D012822Silicon DioxideSilicon Dioxide results in increased expression of and results in increased secretion of IL12B protein12193738
D019821SimvastatinFOS inhibits the reaction [Simvastatin results in increased expression of IL12B mRNA]15187114
D019821SimvastatinJUN promotes the reaction [Simvastatin results in increased expression of IL12B mRNA]15187114
D019821Simvastatin"Simvastatin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]"15187114
D019821Simvastatin"Simvastatin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]"15187114
D019821SimvastatinSimvastatin promotes the reaction [Pam(3)CSK(4) peptide results in increased expression of IL12B protein]15187114
D019821SimvastatinSimvastatin promotes the reaction [resiquimod results in increased expression of IL12B protein]15187114
D019821SimvastatinSimvastatin results in increased expression of IL12B mRNA15187114
D020123SirolimusSirolimus inhibits the reaction [IL4 protein results in increased expression of [IL12A protein binds to IL12B protein]]12531798
C017947sodium arsenitesodium arsenite results in increased expression of IL12B mRNA12760830
D013024Soybean OilSoybean Oil results in decreased expression of IL12B mRNA10065739
C110630SR 144528"SR 144528 inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]"15821753
D013311StreptozocinDronabinol inhibits the reaction [Streptozocin results in increased expression of IL12B mRNA]11357882
D013311StreptozocinStreptozocin results in increased expression of IL12B mRNA11357882
D013427SulfapyridineSulfapyridine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11529938
D012460SulfasalazineSulfasalazine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11529938
D012460SulfasalazineSulfasalazine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12B protein binds to IL12A protein]]11529938
D013448SulfobromophthaleinSulfobromophthalein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]11907163
C016766sulforafanNFE2L2 protein affects the reaction [sulforafan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]16890772
C016766sulforafansulforafan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]16890772
D013498SuraminSuramin results in increased expression of IL12B protein15914193
C029222sym-trinitrobenzeneEicosapentaenoic Acid analog inhibits the reaction [sym-trinitrobenzene results in increased expression of IL12B mRNA]15890784
C029222sym-trinitrobenzeneIL12B protein results in decreased susceptibility to sym-trinitrobenzene11782017
C029222sym-trinitrobenzenesym-trinitrobenzene results in increased expression of IL12B mRNA15890784
C076852terameprocolterameprocol affects the reaction [Lipopolysaccharides results in increased expression of IL12B protein]19133137
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of IL12B mRNA15644576
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of IL12B mRNA15614042
D013792ThalidomideThalidomide results in decreased expression of [IL12A protein binds to IL12B protein]11788559
D013792ThalidomideThalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of IL12B mRNA]16510725
D013806TheophyllineTheophylline results in decreased expression of [IL12A protein binds to IL12B protein]15569413
D013806TheophyllineTheophylline results in decreased expression of IL12B protein15569413
C475227thieno(2,3-c)isoquinolin-5-one"thieno(2,3-c)isoquinolin-5-one inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]"17579050
C009495titanium dioxidetitanium dioxide results in increased expression of IL12B protein23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of IL12B mRNA20133372
C024746tobacco tartobacco tar inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]15894107
C024746tobacco tartobacco tar results in increased expression of IL12B mRNA15894107
C082097tocotrienol, delta"tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]"22185406
C082097tocotrienol, delta"tocotrienol, delta results in decreased expression of IL12B mRNA"22185406
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of IL12B mRNA"11379042
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of IL12B protein"18652873
D001371trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride"trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride results in increased expression of [IL12A protein binds to IL12B protein]"9756745
D001371trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride"trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride results in increased expression of IL12B mRNA"9756745
D014212TretinoinRARA protein affects the reaction [Tretinoin results in decreased secretion of [IL12A protein binds to IL12B protein]]16872382
D014212TretinoinRo 41-5253 inhibits the reaction [Tretinoin results in decreased secretion of [IL12A protein binds to IL12B protein]]16872382
D014212TretinoinTretinoin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]17253143
D014212TretinoinTretinoin results in decreased expression of [IL12A protein binds to IL12B protein]17118196
D014212TretinoinTretinoin results in decreased expression of IL12B mRNA15189689|1687238
C012589trichostatin Atrichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]12470611
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IL12B protein]16249388
C014871trimellitic acidtrimellitic acid results in decreased methylation of IL12B gene26732893
C014871trimellitic acidtrimellitic acid results in increased methylation of IL12B gene26732893
C015559trimellitic anhydridetrimellitic anhydride affects the expression of IL12B mRNA22302311
D014302Trinitrobenzenesulfonic Acidicilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein]23596210
D014302Trinitrobenzenesulfonic AcidIL12B protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid11782017
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA17375199
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of IL12B protein23596210
D014302Trinitrobenzenesulfonic AcidCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]16867261
D014302Trinitrobenzenesulfonic AcidDexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]16867261
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA16867261
D010853Picryl Chloride[Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein17371993
D010853Picryl ChloridePicryl Chloride results in increased expression of IL12B mRNA11708898
D010853Picryl ChloridePPARA protein affects the reaction [[Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein]17371993
C001899triptolidetriptolide results in decreased expression of [IL12A protein binds to IL12B protein]15663903
C001899triptolidetriptolide results in decreased expression of IL12B protein15663903
D014415TunicamycinTunicamycin inhibits the reaction [IL12A protein binds to IL12B protein]10779781
D014415TunicamycinTunicamycin results in decreased secretion of [IL12A protein binds to IL12B protein]10779781
C113580U 0126U 0126 inhibits the reaction [[Histamine results in increased activity of HRH4 protein] which results in decreased expression of IL12B protein]15843518
C113580U 0126U 0126 inhibits the reaction [[IL12A protein binds to IL12B protein] which results in increased expression of IFNG protein]10952721
C113580U 0126U 0126 promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]15778123
C113580U 0126U 0126 promotes the reaction [loxoribine results in increased expression of [IL12A protein binds to IL12B protein]]15777634
C062137U 75302U 75302 promotes the reaction [Zymosan results in increased secretion of IL12B protein]16313356
D014520UrethaneFreund's Adjuvant promotes the reaction [Urethane results in decreased expression of IL12B mRNA]12810352
D058425Vaccines, Virus-Like Particle"Estradiol inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]"20130130
D058425Vaccines, Virus-Like Particle"[Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]"20130130
D058425Vaccines, Virus-Like Particle"Progesterone inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]"20130130
D058425Vaccines, Virus-Like Particle"Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]"20130130
D014635Valproic AcidValproic Acid inhibits the reaction [Mechlorethamine results in increased expression of IL12B mRNA]28184907
D001335Vehicle EmissionsNFE2L2 protein affects the reaction [Vehicle Emissions analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]16890772
D001335Vehicle Emissions"Vehicle Emissions analog inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of IL12B protein]"16890772
D001335Vehicle EmissionsVehicle Emissions analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]16890772
D001335Vehicle EmissionsVehicle Emissions analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]16890772
D001335Vehicle Emissions[Vehicle Emissions co-treated with Ozone] results in decreased expression of [IL12A protein binds to IL12B protein]27058360
D001335Vehicle EmissionsVehicle Emissions inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]]19805405
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of IL12B mRNA11936774|1221721
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of IL12B protein11936774
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL12B mRNA14594659|1600764
D001335Vehicle EmissionsVehicle Emissions results in increased expression of IL12B mRNA24216475
C121611VIVIT peptideVIVIT peptide inhibits the reaction [Zymosan results in increased expression of [IL12A protein binds to IL12B protein]]17312158
D014859WarfarinWarfarin results in increased expression of IL12B mRNA22342526
C009687wortmanninwortmannin inhibits the reaction [C5 protein results in decreased expression of [IL12A protein binds to IL12B protein]]16116186
C009687wortmanninwortmannin inhibits the reaction [C5 protein results in decreased expression of IL12B mRNA]16116186
C009687wortmanninwortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]16116186
C063449zileutonzileuton inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]]19118273
C016837zinc chloridezinc chloride results in decreased expression of IL12B mRNA24284788
D015034Zinc OxideZinc Oxide inhibits the reaction [Dimethylnitrosamine results in increased expression of IL12B protein]29024620
D015054ZymosanCLEC7A protein promotes the reaction [Zymosan results in increased secretion of IL12B protein]18279049
D015054ZymosanIFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]]18490488
D015054ZymosanIFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of IL12B protein]18490488
D015054ZymosanIFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]]18490488
D015054ZymosanIFNG protein promotes the reaction [Zymosan results in increased expression of [IL12A protein binds to IL12B protein]]18490488
D015054ZymosanIFNG protein promotes the reaction [Zymosan results in increased expression of IL12B protein]18490488
D015054ZymosanIFNG protein promotes the reaction [Zymosan results in increased expression of [IL12B protein binds to IL23A protein]]18490488
D015054Zymosan[Zymosan co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]18490488
D015054Zymosan[Zymosan co-treated with resiquimod] results in increased expression of IL12B protein18490488
D015054Zymosan[Zymosan co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]18490488
D015054ZymosanZymosan results in increased expression of [IL12B protein binds to IL23A protein]18490488
D015054ZymosanZymosan results in increased secretion of IL12B protein18279049
D015054ZymosanCyclosporine inhibits the reaction [Zymosan results in increased expression of [IL12A protein binds to IL12B protein]]17312158
D015054Zymosanglucan phosphate inhibits the reaction [Zymosan results in increased expression of IL12B protein]15845454
D015054ZymosanIRF1 protein affects the reaction [Zymosan affects the expression of [IL12A protein binds to IL12B protein]]10415056
D015054ZymosanIRF1 protein affects the reaction [Zymosan affects the expression of IL12B protein]10415056
D015054ZymosanIRF2 protein affects the reaction [Zymosan affects the expression of [IL12A protein binds to IL12B protein]]10415056
D015054Zymosan[Lipopolysaccharides co-treated with Zymosan] results in increased expression of IL12B mRNA15213630
D015054ZymosanMYD88 gene mutant form inhibits the reaction [Zymosan results in increased expression of IL12B protein]15845454
D015054ZymosanTLR2 protein promotes the reaction [Zymosan results in increased expression of [IL12A protein binds to IL12B protein]]17312158
D015054ZymosanU 75302 promotes the reaction [Zymosan results in increased secretion of IL12B protein]16313356
D015054ZymosanVIVIT peptide inhibits the reaction [Zymosan results in increased expression of [IL12A protein binds to IL12B protein]]17312158
D015054ZymosanZymosan results in increased expression of [IL12A protein binds to IL12B protein]17312158
D015054ZymosanZymosan results in increased expression of IL12B protein15845454
D015054ZymosanZymosan results in increased secretion of IL12B protein15618177

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004896cytokine receptor activity-IBA21873635  
GO:0004896cytokine receptor activity-IEA-  
GO:0005125cytokine activitycontributes_toIDA1674604  
GO:0005143interleukin-12 receptor binding-IBA21873635  
GO:0005143interleukin-12 receptor binding-TAS1674604  
GO:0005143interleukin-12 receptor bindingcontributes_toTAS9603733  
GO:0005515protein binding-IPI7527811  10899108  11023671  11114383  12023369  18680750  
GO:0008083growth factor activity-IBA21873635  
GO:0008083growth factor activitycontributes_toIDA1674604  
GO:0019955cytokine binding-IBA21873635  
GO:0042164interleukin-12 alpha subunit binding-IBA21873635  
GO:0042164interleukin-12 alpha subunit binding-IPI11023671  
GO:0042802identical protein binding-IPI7527811  
GO:0042803protein homodimerization activity-IEA-  
GO:0045519interleukin-23 receptor binding-IBA21873635  
GO:0045519interleukin-23 receptor bindingcontributes_toIDA11114383  
GO:0046982protein heterodimerization activity-IPI1674604  11023671  
GO ID GO Term Qualifier Evidence PubMed
GO:0001916positive regulation of T cell mediated cytotoxicity-ISS-  
GO:0002230positive regulation of defense response to virus by host-IDA12421946  
GO:0002230positive regulation of defense response to virus by host-ISS-  
GO:0002323natural killer cell activation involved in immune response-IEA-  
GO:0002827positive regulation of T-helper 1 type immune response-IBA21873635  
GO:0002827positive regulation of T-helper 1 type immune response-IDA15114670  
GO:0002827positive regulation of T-helper 1 type immune response-ISS-  
GO:0002860positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target-IDA7903063  
GO:0002862negative regulation of inflammatory response to antigenic stimulus-IEA-  
GO:0007050cell cycle arrest-IDA16942485  
GO:0008283cell proliferation-IEA-  
GO:0010224response to UV-B-IDA8992506  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0010536positive regulation of activation of Janus kinase activity-IBA21873635  
GO:0010536positive regulation of activation of Janus kinase activity-IDA12023369  
GO:0016477cell migration-IDA7903063  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0019233sensory perception of pain-IEA-  
GO:0019953sexual reproduction-TAS16772281  
GO:0030101natural killer cell activation-IDA1673147  
GO:0032693negative regulation of interleukin-10 production-IMP16751425  
GO:0032700negative regulation of interleukin-17 production-IDA16482511  
GO:0032725positive regulation of granulocyte macrophage colony-stimulating factor production-IDA20027291  
GO:0032729positive regulation of interferon-gamma production-IBA21873635  
GO:0032729positive regulation of interferon-gamma production-IDA1674604  11114383  19088061  20027291  
GO:0032733positive regulation of interleukin-10 production-IDA15265908  
GO:0032733positive regulation of interleukin-10 production-TAS18675459  
GO:0032735positive regulation of interleukin-12 production-IDA20027291  
GO:0032740positive regulation of interleukin-17 production-IDA16482511  16751425  17888176  
GO:0032760positive regulation of tumor necrosis factor production-IMP16751425  
GO:0032816positive regulation of natural killer cell activation-IBA21873635  
GO:0032816positive regulation of natural killer cell activation-IC20027291  
GO:0032816positive regulation of natural killer cell activation-IDA1674604  
GO:0032819positive regulation of natural killer cell proliferation-IDA19088061  
GO:0032946positive regulation of mononuclear cell proliferation-IMP11023671  
GO:0034105positive regulation of tissue remodeling-IC16482511  
GO:0034393positive regulation of smooth muscle cell apoptotic process-IDA16942485  
GO:0035722interleukin-12-mediated signaling pathway-TAS-  
GO:0035744T-helper 1 cell cytokine production-IEA-  
GO:0038155interleukin-23-mediated signaling pathway-TAS-  
GO:0042035regulation of cytokine biosynthetic process-TAS1673147  
GO:0042088T-helper 1 type immune response-TAS1673147  
GO:0042093T-helper cell differentiation-IDA1673147  
GO:0042095interferon-gamma biosynthetic process-TAS1673147  
GO:0042102positive regulation of T cell proliferation-IDA12023369  
GO:0042104positive regulation of activated T cell proliferation-IBA21873635  
GO:0042104positive regulation of activated T cell proliferation-IDA1674604  11114383  
GO:0042509regulation of tyrosine phosphorylation of STAT protein-IDA12023369  
GO:0042531positive regulation of tyrosine phosphorylation of STAT protein-IBA21873635  
GO:0042531positive regulation of tyrosine phosphorylation of STAT protein-IDA12023369  
GO:0042832defense response to protozoan-IEA-  
GO:0043382positive regulation of memory T cell differentiation-ISS-  
GO:0044130negative regulation of growth of symbiont in host-IEA-  
GO:0045078positive regulation of interferon-gamma biosynthetic process-TAS1673147  
GO:0045672positive regulation of osteoclast differentiation-IDA17888176  
GO:0045785positive regulation of cell adhesion-IDA7903063  
GO:0048662negative regulation of smooth muscle cell proliferation-IDA16942485  
GO:0050671positive regulation of lymphocyte proliferation-IBA21873635  
GO:0050671positive regulation of lymphocyte proliferation-IDA1674604  
GO:0050729positive regulation of inflammatory response-IC16482511  
GO:0050829defense response to Gram-negative bacterium-IDA15114670  20027291  
GO:0051135positive regulation of NK T cell activation-IBA21873635  
GO:0051135positive regulation of NK T cell activation-IC20027291  
GO:0051135positive regulation of NK T cell activation-IDA19088061  
GO:0051142positive regulation of NK T cell proliferation-IDA19088061  
GO:0051607defense response to virus-IEA-  
GO:0071222cellular response to lipopolysaccharide-IEA-  
GO:0071346cellular response to interferon-gamma-IEA-  
GO:1901224positive regulation of NIK/NF-kappaB signaling-TAS20428758  
GO:2000318positive regulation of T-helper 17 type immune response-ISS-  
GO:2000330positive regulation of T-helper 17 cell lineage commitment-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-TAS1673147  
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0005829cytosol-TAS-  
GO:0009897external side of plasma membrane-IBA21873635  
GO:0009986cell surface-IEA-  
GO:0016020membrane-IEA-  
GO:0031906late endosome lumen-TAS-  
GO:0043235receptor complex-IBA21873635  
GO:0043514interleukin-12 complex-IBA21873635  
GO:0043514interleukin-12 complex-IDA1674604  11114383  
GO:0070743interleukin-23 complex-IBA21873635  
GO:0070743interleukin-23 complex-IDA11114383  
KEGG ID KEGG Term
hsa04060Cytokine-cytokine receptor interaction
hsa04620Toll-like receptor signaling pathway
hsa04622RIG-I-like receptor signaling pathway
hsa04630Jak-STAT signaling pathway
hsa04940Type I diabetes mellitus
hsa05140Leishmaniasis
hsa05142Chagas disease (American trypanosomiasis)
hsa05143African trypanosomiasis
hsa05145Toxoplasmosis
hsa05146Amoebiasis
hsa05330Allograft rejection
Reactome ID Reactome Term Evidence
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-1280215Cytokine Signaling in Immune systemIEA
R-HSA-168256Immune SystemTAS
R-HSA-168256Immune SystemIEA
R-HSA-447115Interleukin-12 family signalingTAS
R-HSA-447115Interleukin-12 family signalingIEA
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-449147Signaling by InterleukinsIEA
R-HSA-6783783Interleukin-10 signalingTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-9020591Interleukin-12 signalingTAS
R-HSA-9020591Interleukin-12 signalingIEA
R-HSA-9020933Interleukin-23 signalingTAS
R-HSA-9020933Interleukin-23 signalingIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20034760Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis. (2010 May)Chandran VJ Autoimmun
26986948An Interleukin 13 Polymorphism Is Associated with Symptom Severity in Adult Subjects with Ever Asthma. (2016)Accordini SPLoS One
19185507Common polymorphisms in interleukin genes (IL4, IL6, IL8 and IL12) are not associated with alcoholic liver disease or alcoholism in Spanish men. (2009 Mar)Marcos MCytokine
23468464Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-gamma-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment. (2014 Apr)Tillack CGut
22614250Contribution of IL12A and IL12B polymorphisms to the risk of cervical cancer. (2012 Oct)Roszak APathol Oncol Res
29566963Analysis of the relationship between interleukin polymorphisms within miRNA-binding regions and alcoholic liver disease. (2018 May)Novo-Veleiro IRev Clin Esp
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