Gene info: ID 3625

Gene: INHBB

GENE ID: 3625

Synonyms: -

Description: inhibin subunit beta B

Gene type: protein-coding

Location: 2q14.2

dbXrefs: Ensembl:ENSG00000163083 MIM:147390 Vega:OTTHUMG00000131437 UniprotKB:P09529

RefSeq: NC_000002.12

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 1

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 8.988e-1 (AD) 4.197e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
RHOJ	0.817
PLTP	0.807
FKBP10	0.781
RNF135	0.768
SH3BP2	0.765
CHST14	0.76
ARHGEF40	0.757
LRP10	0.755
RREB1	0.749
ABCC9	0.747

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
PTPRR	-0.591
ROBO2	-0.549
TMEFF2	-0.549
EPHA5	-0.546
PPEF1	-0.538
GPR61	-0.535
SPHKAP	-0.534
CDH8	-0.528
SVOP	-0.526
KCNB2	-0.523

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene results in decreased expression of INHBB mRNA"	26377693
C558048	1,7-diphenyl-4,6-heptadien-3-ol	"1,7-diphenyl-4,6-heptadien-3-ol results in increased expression of INHBB mRNA"	25575267
C032668	1-nitropyrene	1-nitropyrene results in increased expression of INHBB mRNA	19041380
C548651	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of INHBB mRNA	19933214
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of INHBB mRNA"	20826375
C029497	2,3-bis(3'-hydroxybenzyl)butyrolactone	"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of INHBB mRNA"	19167446
C016403	2,4-dinitrotoluene	"2,4-dinitrotoluene affects the expression of INHBB mRNA"	21346803
C007997	25-hydroxycholesterol	25-hydroxycholesterol results in increased expression of INHBB mRNA	19464342
C007997	25-hydroxycholesterol	25-hydroxycholesterol results in increased expression of INHBB protein	19464342
C583074	4,4'-hexafluorisopropylidene diphenol	"4,4'-hexafluorisopropylidene diphenol results in decreased expression of INHBB mRNA"	22504055
D000082	Acetaminophen	Acetaminophen results in decreased expression of INHBB mRNA	21420995\|2669055
D000082	Acetaminophen	Acetaminophen results in increased expression of INHBB mRNA	29067470
D000082	Acetaminophen	Acetaminophen affects the expression of INHBB mRNA	17562736
D020106	Acrylamide	Acrylamide results in decreased expression of INHBB mRNA	28959563
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of INHBB protein	20106945
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of INHBB mRNA	19770486
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of INHBB mRNA	16483693
C059765	amphotericin B, deoxycholate drug combination	"amphotericin B, deoxycholate drug combination results in increased expression of INHBB mRNA"	22863853
D001151	Arsenic	Arsenic affects the expression of INHBB protein	24675094
C015001	arsenite	[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of INHBB mRNA	15894712
C015001	arsenite	arsenite results in decreased expression of INHBB mRNA	15894712
D001280	Atrazine	Atrazine results in increased expression of INHBB mRNA	18585445
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in decreased expression of INHBB mRNA	19737606
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of INHBB mRNA	18164116
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of INHBB mRNA	20106945\|2163298
D001564	Benzo(a)pyrene	[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of INHBB mRNA	15894712
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of INHBB mRNA	19770486\|2171566
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of INHBB mRNA	15894712
D004958	Estradiol	Estradiol affects the expression of INHBB mRNA	25321415
D004958	Estradiol	ESR1 protein affects the reaction [Estradiol results in increased expression of INHBB mRNA]	23552522
D004958	Estradiol	Estradiol results in decreased expression of INHBB mRNA	17255206
D004958	Estradiol	Estradiol results in increased expression of INHBB mRNA	15289156\|2004911
C543008	bis(4-hydroxyphenyl)sulfone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of INHBB mRNA	28628672
C006780	bisphenol A	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of INHBB mRNA	28628672
C006780	bisphenol A	bisphenol A results in decreased methylation of INHBB promoter	27312807
C006780	bisphenol A	bisphenol A results in increased expression of INHBB mRNA	20826375
C006780	bisphenol A	bisphenol A affects the expression of INHBB mRNA	21786754
C006780	bisphenol A	bisphenol A affects the expression of INHBB mRNA	25181051
C006780	bisphenol A	bisphenol A results in increased expression of INHBB mRNA	28641706
C000611646	bisphenol F	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of INHBB mRNA	28628672
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased expression of INHBB mRNA	12414654
C018475	butyraldehyde	butyraldehyde results in decreased expression of INHBB mRNA	26079696
C584509	C646 compound	C646 compound results in decreased expression of INHBB mRNA	26191083
D002104	Cadmium	Cadmium results in increased expression of INHBB mRNA	22562489
D002104	Cadmium	Cadmium results in decreased expression of INHBB protein	26424772
D002104	Cadmium	flavocoxid inhibits the reaction [Cadmium results in decreased expression of INHBB protein]	26424772
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of INHBB protein	26424772
D019256	Cadmium Chloride	flavocoxid inhibits the reaction [Cadmium Chloride results in decreased expression of INHBB protein]	26424772
D002509	Cephaloridine	Cephaloridine results in decreased expression of INHBB mRNA	18500788
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of INHBB mRNA	20938992
D002922	Ciguatoxins	Ciguatoxins affects the expression of INHBB mRNA	18353800
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of INHBB mRNA	24386269
D003300	Copper	Copper results in increased expression of INHBB mRNA	22465980
D019327	Copper Sulfate	Copper Sulfate results in increased expression of INHBB mRNA	19549813
D003375	Coumestrol	"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of INHBB mRNA"	19167446
D065366	Cryptoxanthins	Cryptoxanthins inhibits the reaction [Lipopolysaccharides results in decreased expression of INHBB mRNA]	26686910
D065366	Cryptoxanthins	Cryptoxanthins results in increased expression of INHBB mRNA	26686910
D003471	Cuprizone	Cuprizone results in decreased expression of INHBB mRNA	26577399\|2752363
C009160	cyclonite	cyclonite results in decreased expression of INHBB mRNA	25559034
D016572	Cyclosporine	Cyclosporine results in increased expression of INHBB mRNA	20106945\|2163298
C017160	cypermethrin	[cypermethrin co-treated with Diethylhexyl Phthalate] results in decreased expression of INHBB mRNA	24641848
C017160	cypermethrin	cypermethrin results in decreased expression of INHBB mRNA	24641848
C017160	cypermethrin	cypermethrin results in decreased expression of INHBB protein	24641848
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in decreased expression of INHBB mRNA	24317228
D003907	Dexamethasone	Dexamethasone results in increased expression of INHBB mRNA	25047013
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of INHBB mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of INHBB mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of INHBB mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of INHBB mRNA	28628672
D036381	Diarylheptanoids	Diarylheptanoids results in increased expression of INHBB mRNA	23552522
D036381	Diarylheptanoids	ESR1 protein affects the reaction [Diarylheptanoids results in increased expression of INHBB mRNA]	23552522
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of INHBB mRNA	21266533
D002945	Cisplatin	Cisplatin results in decreased expression of INHBB mRNA	27392435
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in decreased expression of INHBB mRNA	16519141\|1987750
D004008	Diclofenac	Diclofenac results in increased expression of INHBB mRNA	26934552
D004041	Dietary Fats	Dietary Fats results in decreased expression of INHBB mRNA	25016146
D019422	Dietary Sucrose	Dietary Sucrose results in increased expression of INHBB mRNA	26033743
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of INHBB protein	26678702
D004051	Diethylhexyl Phthalate	[cypermethrin co-treated with Diethylhexyl Phthalate] results in decreased expression of INHBB mRNA	24641848
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of INHBB mRNA	24641848
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of INHBB protein	24641848
C014476	diethyl maleate	diethyl maleate results in decreased expression of INHBB mRNA	25270620
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of INHBB mRNA	24535843
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of INHBB mRNA	18164116
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of INHBB mRNA	25242112
D004054	Diethylstilbestrol	Diethylstilbestrol results in decreased expression of INHBB mRNA	17255206
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of INHBB mRNA	15289156
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [FSHB protein results in increased expression of INHBB mRNA]	15878960
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of INHBB mRNA"	22485181
D004147	Dioxins	Dioxins results in decreased expression of INHBB protein	21262597
D004964	Estriol	Estriol results in increased expression of INHBB mRNA	25575267
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of INHBB mRNA	16467188\|1755557
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of INHBB mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of INHBB mRNA	28522409
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of INHBB mRNA	17351261
C544478	flavocoxid	flavocoxid inhibits the reaction [Cadmium Chloride results in decreased expression of INHBB protein]	26424772
C544478	flavocoxid	flavocoxid inhibits the reaction [Cadmium results in decreased expression of INHBB protein]	26424772
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of INHBB mRNA	20938992
D004397	Fonofos	Fonofos results in increased methylation of INHBB promoter	22847954
D019833	Genistein	Genistein results in decreased expression of INHBB mRNA	22228119
D019833	Genistein	Genistein results in increased expression of INHBB mRNA	15289156
D006534	Heptachlor Epoxide	Heptachlor Epoxide results in increased expression of INHBB mRNA	25270620
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased expression of INHBB mRNA	12414654
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of INHBB mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of INHBB mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of INHBB mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of INHBB mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of INHBB mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of INHBB mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of INHBB mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of INHBB mRNA	28628672
D007545	Isoproterenol	Isoproterenol results in increased expression of INHBB mRNA	20003209
C008261	lead acetate	lead acetate results in decreased expression of INHBB mRNA	25270620
C008261	lead acetate	lead acetate results in decreased expression of and results in decreased secretion of INHBB protein	29273543
C008261	lead acetate	lead acetate results in decreased expression of and results in decreased secretion of [INHBB protein binds to INHA protein]	29273543
C008261	lead acetate	lead acetate results in decreased expression of INHBB mRNA	29273543
C045463	leflunomide	leflunomide results in increased expression of INHBB mRNA	28988120
D008070	Lipopolysaccharides	Cryptoxanthins inhibits the reaction [Lipopolysaccharides results in decreased expression of INHBB mRNA]	26686910
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of INHBB mRNA	26686910
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of INHBB mRNA	20938992
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in decreased expression of INHBB mRNA	26011545
C583365	N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of INHBB mRNA"	29244179
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog affects the expression of INHBB mRNA"	25620056
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of INHBB mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of INHBB mRNA"	25554681\|2562005
D009532	Nickel	Nickel affects the expression of INHBB mRNA	14575637
D009532	Nickel	Nickel results in decreased expression of INHBB mRNA	24768652\|2558310
D009532	Nickel	trichostatin A inhibits the reaction [Nickel affects the expression of INHBB mRNA]	14575637
C025256	nonylphenol	nonylphenol analog results in increased expression of INHBB protein	25242005
C464660	obeticholic acid	obeticholic acid results in increased expression of INHBB mRNA	27939613
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in increased expression of INHBB mRNA	25729387
D010278	Parathion	Parathion results in increased methylation of INHBB promoter	22847954
C101816	perfluoro-n-nonanoic acid	perfluoro-n-nonanoic acid results in decreased expression of INHBB mRNA	20580666
C101816	perfluoro-n-nonanoic acid	perfluoro-n-nonanoic acid results in decreased expression of INHBB protein	20580666
D010795	Phthalic Acids	Phthalic Acids results in increased expression of INHBB mRNA	22112501
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of INHBB mRNA	19710929
C006253	pirinixic acid	pirinixic acid results in decreased expression of INHBB mRNA	25270620
C006253	pirinixic acid	pirinixic acid results in increased expression of INHBB mRNA	18445702\|2381119
D010936	Plant Extracts	Plant Extracts results in decreased expression of INHBB mRNA	23557933
C027373	potassium chromate(VI)	potassium chromate(VI) results in increased expression of INHBB mRNA	22714537
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of INHBB mRNA	28903501
D011374	Progesterone	Progesterone results in increased expression of INHBB mRNA	21795739
D011441	Propylthiouracil	AKT1 protein mutant form promotes the reaction [Propylthiouracil results in increased expression of INHBB mRNA]	20951798
D011441	Propylthiouracil	Propylthiouracil results in increased expression of INHBB mRNA	20951798
D011441	Propylthiouracil	Propylthiouracil affects the expression of INHBB mRNA	7819453
D011441	Propylthiouracil	Propylthiouracil results in increased expression of INHBB mRNA	24780913
D011794	Quercetin	Quercetin results in increased expression of INHBB mRNA	21632981
D018967	Risperidone	Risperidone results in increased expression of [INHA protein binds to INHBB protein]	18838228
D012822	Silicon Dioxide	Silicon Dioxide analog results in decreased expression of INHBB mRNA	23806026\|2589566
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of INHBB mRNA	23221170
C017947	sodium arsenite	sodium arsenite results in decreased expression of INHBB mRNA	16014739
D014284	Triiodothyronine	FSHB protein promotes the reaction [Triiodothyronine results in increased expression of INHBB mRNA]	7531505
D014284	Triiodothyronine	Triiodothyronine promotes the reaction [FSHB protein results in increased expression of INHBB mRNA]	7531505
D014284	Triiodothyronine	Triiodothyronine results in increased expression of INHBB mRNA	7531505
D013629	Tamoxifen	Tamoxifen affects the expression of INHBB mRNA	20937368
D013629	Tamoxifen	Tamoxifen results in increased expression of INHBB mRNA	17555576
C012568	terbufos	terbufos results in increased methylation of INHBB promoter	22847954
D013739	Testosterone	Testosterone results in decreased expression of INHBB mRNA	22138414
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in decreased expression of INHBB mRNA	25172293
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of INHBB mRNA	20106945\|2163298
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of INHBB mRNA	17942748
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of INHBB mRNA	19933214
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of INHBB mRNA	21215274
C009495	titanium dioxide	titanium dioxide results in increased expression of INHBB mRNA	23557971
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of INHBB mRNA	28065790
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in increased expression of INHBB mRNA	25729387
D019772	Topotecan	Topotecan results in increased expression of INHBB mRNA	25729387
D014118	Toxins, Biological	"Toxins, Biological affects the expression of INHBB mRNA"	19682533
D014212	Tretinoin	Tretinoin results in increased expression of INHBB mRNA	20530235
D014212	Tretinoin	Tretinoin results in decreased expression of INHBB mRNA	23830798
C012589	trichostatin A	trichostatin A inhibits the reaction [Nickel affects the expression of INHBB mRNA]	14575637
C012589	trichostatin A	trichostatin A results in decreased expression of INHBB mRNA	15901671
C015559	trimellitic anhydride	trimellitic anhydride results in increased expression of INHBB mRNA	19042947
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of INHBB mRNA"	26743178
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of INHBB mRNA"	26179874
D014520	Urethane	Urethane results in decreased expression of INHBB mRNA	28818685
D014527	Uric Acid	INHBB gene SNP affects the abundance of Uric Acid	23263486
D014635	Valproic Acid	Valproic Acid results in decreased expression of INHBB mRNA	15901671
D014638	Vanadates	Vanadates results in increased expression of INHBB mRNA	22714537
C029297	vinylidene chloride	vinylidene chloride results in increased expression of INHBB mRNA	26682919
D024483	Vitamin K 3	Vitamin K 3 affects the expression of INHBB mRNA	20044591
D024483	Vitamin K 3	Vitamin K 3 results in increased expression of INHBB mRNA	12414654
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical results in increased expression of INHBB mRNA"	24525044

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005125	cytokine activity	-	IBA	21873635
GO:0005125	cytokine activity	-	TAS	3122219
GO:0005160	transforming growth factor beta receptor binding	-	IBA	21873635
GO:0005179	hormone activity	-	TAS	3122219
GO:0005515	protein binding	-	IPI	2575216 12697670
GO:0008083	growth factor activity	-	IEA	-
GO:0042803	protein homodimerization activity	-	IPI	2575216
GO:0046789	host cell surface receptor binding	-	TAS	12456957

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001541	ovarian follicle development	-	NAS	12790766
GO:0006952	defense response	-	TAS	3122219
GO:0009267	cellular response to starvation	-	ISS	-
GO:0009611	response to wounding	-	IEP	10320815
GO:0010469	regulation of signaling receptor activity	-	IEA	-
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	-	IBA	21873635
GO:0030154	cell differentiation	-	NAS	10320815
GO:0032869	cellular response to insulin stimulus	-	ISS	-
GO:0032924	activin receptor signaling pathway	-	IDA	16650820
GO:0042981	regulation of apoptotic process	-	IBA	21873635
GO:0043408	regulation of MAPK cascade	-	IBA	21873635
GO:0044320	cellular response to leptin stimulus	-	IEA	-
GO:0044650	adhesion of symbiont to host cell	-	IEA	-
GO:0045444	fat cell differentiation	-	ISS	-
GO:0046676	negative regulation of insulin secretion	-	ISS	-
GO:0046881	positive regulation of follicle-stimulating hormone secretion	-	IPI	3122219
GO:0046882	negative regulation of follicle-stimulating hormone secretion	-	IPI	3122219
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	-	IDA	12419948
GO:0048468	cell development	-	IBA	21873635
GO:0048599	oocyte development	-	IEA	-
GO:0060279	positive regulation of ovulation	-	ISS	-
GO:0060395	SMAD protein signal transduction	-	IBA	21873635
GO:2001235	positive regulation of apoptotic signaling pathway	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005576	extracellular region	-	TAS	3122219
GO:0005615	extracellular space	-	IBA	21873635
GO:0048471	perinuclear region of cytoplasm	-	IDA	16650820
GO:0071944	cell periphery	-	IEA	-

KEGG ID	KEGG Term
hsa04060	Cytokine-cytokine receptor interaction
hsa04350	TGF-beta signaling pathway

Reactome ID	Reactome Term	Evidence
R-HSA-1502540	Signaling by Activin	TAS
R-HSA-1502540	Signaling by Activin	IEA
R-HSA-162582	Signal Transduction	TAS
R-HSA-162582	Signal Transduction	IEA
R-HSA-209822	Glycoprotein hormones	TAS
R-HSA-209952	Peptide hormone biosynthesis	TAS
R-HSA-2473224	Antagonism of Activin by Follistatin	TAS
R-HSA-2980736	Peptide hormone metabolism	TAS
R-HSA-392499	Metabolism of proteins	TAS
R-HSA-9006936	Signaling by TGF-beta family members	TAS
R-HSA-9006936	Signaling by TGF-beta family members	IEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
19334046	Current smoking-specific gene expression signature in normal bronchial epithelium is enhanced in squamous cell lung cancer. (2009 Jun)	Boelens MC	J Pathol