Gene: AQP9

366
AQP-9|HsT17287|SSC1|T17287
aquaporin 9
protein-coding
15q21.3
Ensembl:ENSG00000103569 MIM:602914 Vega:OTTHUMG00000132631 UniprotKB:O43315
NG_011975.2
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.784e-2 (AD)  2.851e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs11854297chr15:58182926 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NLRC40.61
ST140.594
HK30.591
WNT5A0.581
MAN1A10.58
DOK30.578
KCNK130.577
SLC16A100.576
CD300E0.57
NABP10.566

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HHATL-0.348
HES6-0.342
PYGM-0.308
SLC25A48-0.305
CA14-0.296
PACSIN3-0.296
HPDL-0.294
COL9A2-0.293
CMTM5-0.287
ZNRF4-0.285

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of AQP9 mRNA"19114083
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in decreased expression of AQP9 mRNA"21724226
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in decreased expression of AQP9 mRNA"21724226
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dihydrotestosterone results in decreased expression of AQP9 mRNA]20378617
C4861844,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in decreased expression of AQP9 mRNA"22114114
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of AQP9 mRNA"18648102
D000082AcetaminophenAcetaminophen results in decreased expression of AQP9 mRNA21420995|2906747
D016604Aflatoxin B1Aflatoxin B1 affects the expression of AQP9 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of AQP9 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of AQP9 mRNA19770486
D013196Dihydrotestosterone2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dihydrotestosterone results in decreased expression of AQP9 mRNA]20378617
D013196DihydrotestosteroneDihydrotestosterone results in decreased expression of AQP9 mRNA20378617
D013196DihydrotestosteroneDihydrotestosterone results in decreased expression of AQP9 protein20378617
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of AQP9 mRNA17026757
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of AQP9 protein17026757
D000643Ammonium ChlorideAmmonium Chloride affects the expression of AQP9 mRNA16483693
D015113Androstane-3,17-diol"Androstane-3,17-diol results in increased expression of AQP9 mRNA"17026757
D015113Androstane-3,17-diol"Androstane-3,17-diol results in increased expression of AQP9 protein"17026757
D000965AntimonyAQP9 protein results in increased uptake of and results in increased susceptibility to Antimony15336539
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of AQP9 mRNA24449571
D001151ArsenicArsenic results in increased expression of AQP9 mRNA23866971|2861501
C006632arsenic trioxideAQP9 protein affects the uptake of and affects the susceptibility to arsenic trioxide23563754
C006632arsenic trioxideAQP9 protein results in increased import of arsenic trioxide16968895
C006632arsenic trioxideAQP9 protein results in increased susceptibility to arsenic trioxide16968895
C006632arsenic trioxideAQP9 protein results in increased uptake of and results in increased susceptibility to arsenic trioxide15336539
C006632arsenic trioxideAQP9 protein results in increased uptake of arsenic trioxide19100828
C006632arsenic trioxidearsenic trioxide affects the expression of AQP9 protein19100828
C006632arsenic trioxidearsenic trioxide results in increased expression of AQP9 protein21945491
C006632arsenic trioxide[Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of arsenic trioxide25953102
C006632arsenic trioxide[Tretinoin co-treated with arsenic trioxide] results in increased expression of AQP9 mRNA19225113
C006632arsenic trioxide[Tretinoin results in increased expression of AQP9 mRNA] which results in increased import of arsenic trioxide16968895
C006632arsenic trioxide[Tretinoin results in increased expression of AQP9 mRNA] which results in increased susceptibility to arsenic trioxide16968895
C015001arseniteAQP9 protein results in increased uptake of arsenite11972053
C015001arseniteAQP9 protein results in increased susceptibility to arsenite19341753
C015001arseniteAQP9 protein results in increased uptake of arsenite19341753
C015001arseniteSorbitol inhibits the reaction [AQP9 protein results in increased uptake of arsenite]19341753
D001374AzacitidineAzacitidine results in increased expression of AQP9 mRNA25953102
D001374Azacitidine[Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of arsenic trioxide25953102
D001374AzacitidineHNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA]25953102
C547126AZM551248AZM551248 results in increased expression of AQP9 mRNA22323515
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of AQP9 mRNA20064835
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of AQP9 mRNA19770486
D004958EstradiolEstradiol results in decreased expression of AQP9 mRNA22114114
D004958Estradiol[Estradiol results in decreased expression of AQP9 mRNA] which results in decreased uptake of Glycerol22114114
D004958EstradiolEstradiol results in increased expression of AQP9 mRNA17026757|2038159
D004958EstradiolEstradiol results in increased expression of AQP9 protein17026757
D004958EstradiolIsoflavones inhibits the reaction [Estradiol results in increased expression of AQP9 mRNA]20381596
C006780bisphenol Abisphenol A results in decreased expression of AQP9 mRNA25181051
C086539BQ 788BQ 788 inhibits the reaction [EDN1 protein results in decreased expression of AQP9 mRNA]21259319
D002185CannabidiolCannabidiol results in increased expression of AQP9 mRNA21542829
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of AQP9 mRNA16644059
D002784CholesterolCholesterol results in increased expression of AQP9 mRNA26296894
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AQP9 mRNA20938992
D003035Cobalt[tungsten carbide co-treated with Cobalt] results in decreased expression of AQP9 mRNA18078969
D016572CyclosporineCyclosporine results in decreased expression of AQP9 mRNA20106945
D016572CyclosporineCyclosporine results in increased expression of AQP9 mRNA27989131
D013759DronabinolDronabinol results in increased expression of AQP9 mRNA21542829
D003703DemecolcineDemecolcine results in increased expression of AQP9 mRNA23649840
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of AQP9 mRNA21266533
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in increased expression of AQP9 mRNA26924002
D019259Lamivudine[Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA18313992
D004026DieldrinDieldrin results in decreased expression of AQP9 mRNA23153324
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of AQP9 mRNA19638242
C024629dimethyl phthalatedimethyl phthalate results in increased expression of AQP9 mRNA26924002
D004726Endosulfan[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AQP9 mRNA26159488
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of AQP9 mRNA17108234
D011345FenofibrateFenofibrate results in decreased expression of AQP9 mRNA25572481
C082360fipronilfipronil results in decreased expression of AQP9 mRNA23962444
D005472FluorouracilAQP9 protein results in increased uptake of Fluorouracil9733774
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AQP9 mRNA20938992
D005557FormaldehydeFormaldehyde results in increased expression of AQP9 mRNA23649840
D019833GenisteinGenistein results in decreased expression of AQP9 mRNA20381596
D005990GlycerolAQP9 gene mutant form results in increased abundance of Glycerol17360690
D005990GlycerolAQP9 protein affects the uptake of and affects the metabolism of Glycerol17360690
D005990GlycerolAQP9 protein results in increased transport of Glycerol10205677
D005990GlycerolAQP9 protein results in increased uptake of Glycerol22114114|9733774
D005990Glycerol[Estradiol results in decreased expression of AQP9 mRNA] which results in decreased uptake of Glycerol22114114
D006533HeptachlorHeptachlor results in decreased expression of AQP9 mRNA23153324
D017313FenretinideFenretinide results in increased expression of AQP9 mRNA28973697
D0201553-Hydroxybutyric AcidAQP9 protein results in increased uptake of 3-Hydroxybutyric Acid9733774
C027185indirubin[indirubin co-treated with tanshinone] promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
C027185indirubinindirubin promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 mRNA]18344322
C027185indirubinindirubin promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
C027185indirubin[[tetraarsenic tetrasulfide co-treated with indirubin] results in increased expression of AQP9 protein] which results in increased uptake of tetraarsenic tetrasulfide18344322
C027185indirubin[tetraarsenic tetrasulfide co-treated with tanshinone co-treated with indirubin] results in increased expression of AQP9 protein18344322
C027185indirubin[[tetraarsenic tetrasulfide co-treated with tanshinone co-treated with indirubin] results in increased expression of AQP9 protein] which results in increased uptake of tetraarsenic tetrasulfide18344322
C474021indirubin-3'-monoximeindirubin-3'-monoxime promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 mRNA]18344322
C474021indirubin-3'-monoximeindirubin-3'-monoxime promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
D007529IsoflavonesIsoflavones inhibits the reaction [Estradiol results in increased expression of AQP9 mRNA]20381596
C098607JP8 aviation fuelJP8 aviation fuel results in decreased expression of AQP9 protein17337753
D019344Lactic AcidAQP9 protein results in increased uptake of Lactic Acid9733774
C016371lonidaminelonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]12606488
D008353MannitolAQP9 protein results in increased uptake of Mannitol9733774
D008627Mercuric ChlorideMercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]9514918
D008627Mercuric ChlorideMercuric Chloride results in decreased activity of AQP9 protein9514918
D008627Mercuric ChlorideMercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]10205677|2211411
D008627Mercuric ChlorideMercuric Chloride results in decreased activity of AQP9 protein9733774
D008628MercuryMercury inhibits the reaction [AQP9 protein results in increased transport of Water]21259319
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of AQP9 mRNA20938992
D008917MirexMirex results in decreased expression of AQP9 mRNA23153324
C517284monomethyl phthalatemonomethyl phthalate results in increased expression of AQP9 mRNA26924002
C029938nickel sulfatenickel sulfate results in decreased expression of AQP9 mRNA18651567
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of AQP9 mRNA17616710
D009966OrphenadrineOrphenadrine affects the expression of AQP9 mRNA23665939
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of AQP9 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of AQP9 mRNA25729387
D052638Particulate MatterParticulate Matter results in increased expression of AQP9 mRNA28341207
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid affects the expression of AQP9 mRNA19429403
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of AQP9 mRNA18692542
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of AQP9 mRNA17560707|1916217
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of AQP9 mRNA19429403
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of AQP9 mRNA19162173
D010693PhloretinPhloretin inhibits the reaction [AQP9 protein results in increased transport of Water]9733774
D010693PhloretinPhloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]12606488
D010693PhloretinPhloretin results in decreased activity of AQP9 protein21259319|9733774
D010693PhloretinPhloretin results in decreased activity of AQP9 protein12606488
D010882Piperonyl ButoxidePiperonyl Butoxide results in decreased expression of AQP9 mRNA22484513
C006253pirinixic acidpirinixic acid results in decreased expression of AQP9 mRNA18445702
C006253pirinixic acidpirinixic acid results in decreased expression of AQP9 mRNA19162173|2248451
D011192Potassium DichromatePotassium Dichromate results in decreased expression of AQP9 mRNA23608068
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of AQP9 mRNA19162173
D011794QuercetinQuercetin results in decreased expression of AQP9 mRNA28431985
D011794QuercetinQuercetin results in decreased expression of AQP9 protein28431985
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of AQP9 mRNA"24160326
C017947sodium arseniteAQP9 gene mutant form results in increased susceptibility to sodium arsenite19805235
C017947sodium arseniteAQP9 protein affects the transport of sodium arsenite19805235
C017947sodium arsenitesodium arsenite results in decreased expression of AQP9 mRNA29108910
C017947sodium arsenitesodium arsenite results in increased expression of AQP9 mRNA19733843
C017947sodium arsenitesodium arsenite results in increased expression of AQP9 protein19733843
D013012SorbitolSorbitol inhibits the reaction [AQP9 protein results in increased uptake of arsenite]19341753
D013012SorbitolAQP9 protein results in increased uptake of Sorbitol9733774
D013311StreptozocinStreptozocin results in increased expression of AQP9 protein22114114
D020058StyreneStyrene results in increased expression of AQP9 mRNA17654243
D013629TamoxifenTamoxifen inhibits the reaction [ESR1 protein mutant form results in decreased expression of AQP9 mRNA]23213263
D013629TamoxifenTamoxifen inhibits the reaction [ESR1 protein mutant form results in decreased expression of AQP9 protein]23213263
D013629TamoxifenTamoxifen results in decreased expression of AQP9 mRNA23213263
C021751tanshinone[indirubin co-treated with tanshinone] promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
C021751tanshinonetanshinone promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 mRNA]18344322
C021751tanshinonetanshinone promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
C021751tanshinone[tetraarsenic tetrasulfide co-treated with tanshinone co-treated with indirubin] results in increased expression of AQP9 protein18344322
C021751tanshinone[[tetraarsenic tetrasulfide co-treated with tanshinone co-treated with indirubin] results in increased expression of AQP9 protein] which results in increased uptake of tetraarsenic tetrasulfide18344322
C021751tanshinone[[tetraarsenic tetrasulfide co-treated with tanshinone] results in increased expression of AQP9 protein] which results in increased uptake of tetraarsenic tetrasulfide18344322
C501413tesaglitazartesaglitazar results in decreased expression of AQP9 mRNA21515302
D013739TestosteroneTestosterone results in decreased expression of AQP9 mRNA21669218
C534735tetraarsenic tetrasulfideindirubin-3'-monoxime promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 mRNA]18344322
C534735tetraarsenic tetrasulfideindirubin-3'-monoxime promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
C534735tetraarsenic tetrasulfide[indirubin co-treated with tanshinone] promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
C534735tetraarsenic tetrasulfideindirubin promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 mRNA]18344322
C534735tetraarsenic tetrasulfideindirubin promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
C534735tetraarsenic tetrasulfidetanshinone promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 mRNA]18344322
C534735tetraarsenic tetrasulfidetanshinone promotes the reaction [tetraarsenic tetrasulfide results in increased expression of AQP9 protein]18344322
C534735tetraarsenic tetrasulfide[[tetraarsenic tetrasulfide co-treated with indirubin] results in increased expression of AQP9 protein] which results in increased uptake of tetraarsenic tetrasulfide18344322
C534735tetraarsenic tetrasulfide[tetraarsenic tetrasulfide co-treated with tanshinone co-treated with indirubin] results in increased expression of AQP9 protein18344322
C534735tetraarsenic tetrasulfide[[tetraarsenic tetrasulfide co-treated with tanshinone co-treated with indirubin] results in increased expression of AQP9 protein] which results in increased uptake of tetraarsenic tetrasulfide18344322
C534735tetraarsenic tetrasulfide[[tetraarsenic tetrasulfide co-treated with tanshinone] results in increased expression of AQP9 protein] which results in increased uptake of tetraarsenic tetrasulfide18344322
C534735tetraarsenic tetrasulfidetetraarsenic tetrasulfide results in increased expression of AQP9 mRNA18344322
C534735tetraarsenic tetrasulfidetetraarsenic tetrasulfide results in increased expression of AQP9 protein18344322
D013749Tetrachlorodibenzodioxin[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AQP9 mRNA26159488
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of AQP9 mRNA20106945|2615948
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of AQP9 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of AQP9 mRNA18796159
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of AQP9 mRNA19490992|2121527
D013890ThioureaAQP9 protein results in increased uptake of Thiourea9733774
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of AQP9 mRNA25729387
D014212Tretinoin[Tretinoin co-treated with arsenic trioxide] results in increased expression of AQP9 mRNA19225113
D014212TretinoinTretinoin results in increased expression of AQP922940758
D014212TretinoinTretinoin results in increased expression of AQP9 mRNA16968895
D014212Tretinoin[Tretinoin results in increased expression of AQP9 mRNA] which results in increased import of arsenic trioxide16968895
D014212Tretinoin[Tretinoin results in increased expression of AQP9 mRNA] which results in increased susceptibility to arsenic trioxide16968895
D014212TretinoinTretinoin results in increased expression of AQP9 protein16968895
D014280TriglyceridesAQP9 gene mutant form results in increased abundance of Triglycerides17360690
C057693troglitazonetroglitazone results in decreased expression of AQP9 mRNA25572481
C057693troglitazonetroglitazone results in increased expression of AQP9 mRNA21515302
C002802tungsten carbide[tungsten carbide co-treated with Cobalt] results in decreased expression of AQP9 mRNA18078969
C022884undecaneundecane results in decreased expression of AQP9 protein17337753
D014508UreaAQP9 protein results in increased transport of Urea9514918
D014508UreaAQP9 protein results in increased transport of Urea10205677
D014527Uric AcidAQP9 mRNA affects the reaction [Uric Acid results in increased secretion of IL1B protein]21051542
C406224valdecoxibvaldecoxib results in decreased expression of AQP9 mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of AQP9 mRNA17963808
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of AQP9 gene25560391
C025643vinclozolinvinclozolin affects the expression of AQP9 mRNA19015723
D014750VincristineVincristine results in increased expression of AQP9 mRNA23649840
D000225AdenineAQP9 protein results in increased uptake of Adenine9733774
D014807Vitamin DVitamin D results in increased expression of AQP9 protein15336539
D014867WaterAQP9 protein results in increased transport of Water9514918
D014867WaterMercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]9514918
D014867WaterAQP9 protein affects the transport of Water12606488
D014867WaterAQP9 protein results in increased transport of Water10205677|2125931
D014867WaterCFTR protein promotes the reaction [AQP9 protein affects the transport of Water]12606488
D014867Waterlonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]12606488
D014867WaterMercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]10205677|2211411
D014867WaterMercury inhibits the reaction [AQP9 protein results in increased transport of Water]21259319
D014867WaterPhloretin inhibits the reaction [AQP9 protein results in increased transport of Water]9733774
D014867WaterPhloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]12606488
D015215Zidovudine[Zidovudine co-treated with IFNA1 protein] results in increased expression of AQP9 mRNA20370541
D015215Zidovudine[Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA18313992

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005275amine transmembrane transporter activity-TAS9733774  
GO:0005345purine nucleobase transmembrane transporter activity-IDA9733774  
GO:0005350pyrimidine nucleobase transmembrane transporter activity-IDA9733774  
GO:0005372water transmembrane transporter activity-TAS9733774  
GO:0015166polyol transmembrane transporter activity-TAS9733774  
GO:0015204urea transmembrane transporter activity-IBA21873635  
GO:0015250water channel activity-EXP1373524  1510932  7530250  9369468  9405233  9806845  
9829975  10318966  10510269  10564231  11001937  11034202  
11076974  11573934  12084581  14701836  15948717  16596446  
17178220  18202181  18501347  18511455  18762715  21251984  
GO:0015250water channel activity-IDA9733774  
GO:0015254glycerol channel activity-EXP9369468  9405233  10510269  10564231  11573934  12084581  
16596446  18762715  
GO:0015265urea channel activity-EXP10564231  11573934  12084581  18762715  
GO:0015288porin activity-NAS9733774  
GO:0046943carboxylic acid transmembrane transporter activity-TAS9733774  
GO ID GO Term Qualifier Evidence PubMed
GO:0006833water transport-IDA9733774  
GO:0006833water transport-TAS-  
GO:0006863purine nucleobase transport-IDA9733774  
GO:0006955immune response-TAS9514918  
GO:0006970response to osmotic stress-TAS9733774  
GO:0007588excretion-TAS9733774  
GO:0010033response to organic substance-IDA9733774  
GO:0015722canalicular bile acid transport-IEA-  
GO:0015791polyol transport-IDA9733774  
GO:0015793glycerol transport-TAS-  
GO:0015837amine transport-IDA9733774  
GO:0015855pyrimidine nucleobase transport-IDA9733774  
GO:0030104water homeostasis-NAS9733774  
GO:0046689response to mercury ion-IDA9733774  
GO:0046942carboxylic acid transport-TAS9733774  
GO:0071320cellular response to cAMP-IEP17636236  
GO:0071918urea transmembrane transport-IEA-  
GO:0072531pyrimidine-containing compound transmembrane transport-IEA-  
GO:1904823purine nucleobase transmembrane transport-IEA-  
GO:1905039carboxylic acid transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-TAS9514918  
GO:0016021integral component of membrane-NAS9733774  
GO:0016323basolateral plasma membrane-IEA-  
GO:0043231intracellular membrane-bounded organelle-IDA18718702  
KEGG ID KEGG Term
hsa04976Bile secretion
Reactome ID Reactome Term Evidence
R-HSA-382551Transport of small moleculesTAS
R-HSA-432030Transport of glycerol from adipocytes to the liver by AquaporinsTAS
R-HSA-432047Passive transport by AquaporinsTAS
R-HSA-445717Aquaporin-mediated transportTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal