Gene: CD82

3732
4F9|C33|GR15|IA4|KAI1|R2|SAR2|ST6|TSPAN27
CD82 molecule
protein-coding
11p11.2
Ensembl:ENSG00000085117 MIM:600623 Vega:OTTHUMG00000166472 UniprotKB:P27701
NG_023234.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.473e-1 (AD)  2.133e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg07441944chr11:44623459CD821.400e-12Smoking27651444

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
VWA10.882
PREX10.864
CYP27A10.846
RRBP10.845
PLIN30.829
DDR10.827
CDC42EP10.817
C1orf1980.81
RHOG0.807
LGALS3BP0.807

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FREM3-0.446
CNTN5-0.443
FBLN7-0.423
TPBG-0.407
HS6ST3-0.405
STYK1-0.404
CUX2-0.402
PRSS12-0.401
GPR26-0.398
SERTM1-0.393

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C04678311,12-epoxy-5,8,14-eicosatrienoic acid"11,12-epoxy-5,8,14-eicosatrienoic acid inhibits the reaction [Terfenadine analog results in increased expression of CD82 protein]"19289568
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CD82 mRNA"19114083
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of CD82 mRNA"21346803
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in increased expression of CD82 protein26194647
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CD82 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CD82 mRNA"27188386
D000447AldehydesAldehydes results in increased expression of CD82 mRNA25014914
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CD82 mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of CD82 mRNA24449571
D001205Ascorbic AcidAscorbic Acid results in increased expression of CD82 mRNA15372504
D004958EstradiolEstradiol promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD82 protein]21685244
D004958EstradiolEstradiol results in decreased expression of CD82 protein21685244
D004958Estradiol[Estradiol co-treated with Tamoxifen] results in increased expression of CD82 mRNA17823450
D004958EstradiolEstradiol results in increased expression of CD82 mRNA17823450
C006780bisphenol Abisphenol A results in decreased expression of CD82 mRNA23557687
C006780bisphenol Abisphenol A results in increased expression of CD82 mRNA25181051
D000069286BortezomibBortezomib results in decreased expression of CD82 mRNA20977926
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of CD82 mRNA15336504
C018475butyraldehydebutyraldehyde results in increased expression of CD82 mRNA26079696
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of CD82 mRNA17484886
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in decreased expression of CD82 mRNA26272509
D002994ClofibrateClofibrate results in decreased expression of CD82 mRNA23811191
D003471CuprizoneCuprizone results in decreased expression of CD82 mRNA26577399|2752363
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of CD82 mRNA17823450
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CD82 mRNA21266533
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of CD82 mRNA27392435
D002945CisplatinCisplatin results in increased expression of CD82 mRNA27392435|2759478
D004041Dietary FatsDietary Fats results in decreased expression of CD82 mRNA18042831
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CD82 mRNA17823450
D002117CalcitriolCalcitriol results in increased expression of CD82 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of CD82 mRNA21592394
D004281Docosahexaenoic AcidsDocosahexaenoic Acids results in decreased expression of CD82 mRNA16623957
D005485FlutamideFlutamide results in decreased expression of CD82 mRNA24136188
D005557FormaldehydeFormaldehyde results in increased expression of CD82 mRNA23649840
D019833GenisteinGenistein results in increased expression of CD82 mRNA18847459
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of CD82 mRNA22634610
D017313FenretinideFenretinide results in increased expression of CD82 mRNA28973697
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD82 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of CD82 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CD82 mRNA24796395
D007854LeadLead results in decreased expression of CD82 mRNA19921347
C042720mercuric bromidemercuric bromide results in decreased expression of CD82 mRNA26272509
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of CD82 mRNA23103053
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of CD82 mRNA28001369
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of CD82 mRNA"20188158
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of CD82 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CD82 mRNA"25620056
C051752nefazodonenefazodone results in decreased expression of CD82 mRNA24136188
C029938nickel sulfatenickel sulfate results in increased expression of CD82 mRNA22714537
C012655nimesulidenimesulide results in decreased expression of CD82 mRNA24136188
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of CD82 mRNA25729387
D000073878Palm OilPalm Oil results in decreased expression of CD82 mRNA18042831
D052638Particulate MatterParticulate Matter results in decreased expression of CD82 mRNA24769257
D010416PentachlorophenolPentachlorophenol results in decreased expression of CD82 mRNA23892564
C046012pentanalpentanal results in increased expression of CD82 mRNA26079696
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of CD82 mRNA19162173
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of CD82 mRNA19162173
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased expression of CD82 mRNA26678675
C006253pirinixic acidpirinixic acid results in decreased expression of CD82 mRNA17426115|2381119
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of CD82 mRNA22714537
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of CD82 mRNA19162173
C005556propionaldehydepropionaldehyde results in increased expression of CD82 mRNA26079696
C010313pseudocumenepseudocumene results in decreased expression of CD82 protein17337753
C410733scriptaidscriptaid affects the expression of CD82 mRNA18813790
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CD82 mRNA25895662
D012999SomanSoman results in increased expression of CD82 mRNA19281266
D013629Tamoxifen[Estradiol co-treated with Tamoxifen] results in increased expression of CD82 mRNA17823450
D016593Terfenadine"11,12-epoxy-5,8,14-eicosatrienoic acid inhibits the reaction [Terfenadine analog results in increased expression of CD82 protein]"19289568
D016593TerfenadineTerfenadine analog results in increased expression of CD82 protein19289568
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of CD82 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of CD82 mRNA21592394
D013749TetrachlorodibenzodioxinEstradiol promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD82 protein]21685244
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CD82 protein21685244
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CD82 mRNA21570461
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD82 mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of CD82 mRNA28065790
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of CD82 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of CD82 mRNA"19682533
D014212TretinoinTretinoin results in increased expression of CD82 mRNA20488242
C113580U 0126U 0126 inhibits the reaction [CD82 protein affects the expression of TIMP1]20075392
C022884undecaneundecane results in decreased expression of CD82 protein17337753
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CD82 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of CD82 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of CD82 mRNA26272509
D014635Valproic AcidValproic Acid results in increased expression of CD82 mRNA29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI15205336  
GO ID GO Term Qualifier Evidence PubMed
GO:0007166cell surface receptor signaling pathway-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS7754374  
GO:0005887integral component of plasma membrane-IBA21873635  
GO:0005887integral component of plasma membrane-TAS1842498  
GO:0070062extracellular exosome-HDA19199708  20458337  
KEGG ID KEGG Term
hsa04115p53 signaling pathway
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24201754Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia. (2013 Nov 26)Nankivell PBr J Cancer