Gene: ANKRD36

375248
UNQ2430
ankyrin repeat domain 36
protein-coding
2q11.2
Ensembl:ENSG00000135976 Vega:OTTHUMG00000155256 UniprotKB:A6QL64
NC_000002.12
PubMed
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.352e-1 (AD)  3.382e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ANKRD36C0.888
DOPEY10.828
TARBP10.824
MTR0.815
GK50.81
PIGL0.8
DNAH10.798
ZNF3820.798
TBC1D320.793
ZNF5870.793

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PPP1R14B-0.405
CCDC102A-0.4
S100A1-0.372
VAX2-0.359
FOXJ1-0.354
C7orf61-0.353
RAB13-0.35
ROM1-0.346
AKR1C3-0.334
HSPB1-0.332

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000643Ammonium ChlorideAmmonium Chloride affects the expression of ANKRD36 mRNA16483693
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ANKRD36 mRNA"26238291
C006780bisphenol Abisphenol A affects the expression of ANKRD36 mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of ANKRD36 mRNA25181051
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ANKRD36 mRNA22079256
D005472FluorouracilFluorouracil results in increased expression of ANKRD36 mRNA16510598
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ANKRD36 mRNA23649840
C028577monobutyl phthalatemonobutyl phthalate results in increased expression of ANKRD36 mRNA29162477
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ANKRD36 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of ANKRD36 mRNA22079256
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of ANKRD36 mRNA25895662
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of ANKRD36 mRNA27914987
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ANKRD36 mRNA21570461
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of ANKRD36 mRNA28065790
D014241TrichloroethyleneTrichloroethylene results in increased methylation of ANKRD36 gene27618143
D014635Valproic AcidValproic Acid results in decreased expression of ANKRD36 mRNA23179753|2718838

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26036284Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. (2015 Jul)Xu KAlcohol Clin Exp Res