Gene: RBM43

375287
C2orf38
RNA binding motif protein 43
protein-coding
2q23.3
Ensembl:ENSG00000184898 Vega:OTTHUMG00000131866 UniprotKB:Q6ZSC3
NC_000002.12
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.133e-1 (AD)  4.962e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DDX600.799
MR10.769
CTSO0.759
HFE0.743
CD3020.742
UEVLD0.741
TSPAN60.739
SULT1C40.737
CD1090.737
TLR30.735

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RHO-0.413
KCNG2-0.394
NPW-0.385
GALNT14-0.381
WFIKKN1-0.368
NPAS1-0.362
MIP-0.361
MAGIX-0.36
NANOS3-0.353
LAMB3-0.344

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of RBM43 mRNA"23829299
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane affects the expression of RBM43 mRNA"18648102
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of RBM43 mRNA"18648102
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of RBM43 mRNA22228805
C006780bisphenol Abisphenol A results in increased expression of RBM43 mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of RBM43 mRNA26079696
D019256Cadmium ChlorideCadmium Chloride results in increased expression of RBM43 mRNA21457566
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of RBM43 mRNA21266533
D004041Dietary FatsDietary Fats affects the expression of RBM43 mRNA19680557
D004237DiuronDiuron results in increased expression of RBM43 mRNA25152437
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of RBM43 mRNA17555576
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of RBM43 mRNA23649840
D005557FormaldehydeFormaldehyde results in increased expression of RBM43 mRNA23649840
C016517indole-3-carbinolindole-3-carbinol affects the expression of RBM43 mRNA21396975
D008694Methamphetamine[Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM43 mRNA19564919
D008694MethamphetamineMethamphetamine results in decreased expression of RBM43 mRNA19564919
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of RBM43 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of RBM43 mRNA23649840
D008770MethylnitrosoureaMethylnitrosourea results in decreased expression of RBM43 mRNA25270620
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of RBM43 mRNA"25554681
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of RBM43 mRNA25729387
C030110oxaliplatinoxaliplatin results in decreased expression of RBM43 mRNA25729387
D000073878Palm OilPalm Oil affects the expression of RBM43 mRNA19680557
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of RBM43 mRNA26272509
D010416PentachlorophenolPentachlorophenol results in increased expression of RBM43 mRNA23892564
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of RBM43 mRNA]19482888
D010634PhenobarbitalPhenobarbital results in increased expression of RBM43 mRNA19482888
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of RBM43 mRNA26272509
C534628SCH 23390[Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM43 mRNA19564919
C534628SCH 23390SCH 23390 results in decreased expression of RBM43 mRNA19564919
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of RBM43 mRNA21570461
D013853ThioacetamideThioacetamide results in increased expression of RBM43 mRNA23411599
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of RBM43 mRNA25729387
D019772TopotecanTopotecan results in decreased expression of RBM43 mRNA25729387
D014212TretinoinTretinoin results in increased expression of RBM43 mRNA21934132
D014241TrichloroethyleneTrichloroethylene results in increased methylation of RBM43 gene27618143
C012589trichostatin Atrichostatin A results in increased expression of RBM43 mRNA24935251
D014520UrethaneUrethane results in decreased expression of RBM43 mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of RBM43 mRNA23179753|2800136
D014635Valproic AcidValproic Acid results in increased expression of RBM43 mRNA26272509
D001335Vehicle EmissionsVehicle Emissions affects the methylation of RBM43 gene25560391
C025643vinclozolinvinclozolin results in decreased expression of RBM43 mRNA22570695
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RBM43 mRNA"27188386
C111237vorinostatvorinostat results in increased expression of RBM43 mRNA26272509

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29551738Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. (2018 Mar 15)Dong JClin Gastroenterol Hepatol