Gene: KCNH2

3757
ERG-1|ERG1|H-ERG|HERG|HERG1|Kv11.1|LQT2|SQT1
potassium voltage-gated channel subfamily H member 2
protein-coding
7q36.1
Ensembl:ENSG00000055118 MIM:152427 Vega:OTTHUMG00000158341 UniprotKB:Q12809
NG_008916.1
PubMed
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.517e-1 (AD)  7.867e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC4A30.941
SYT30.931
SPTBN40.93
NYAP10.926
ABLIM20.926
PTPRN0.925
CDK5R20.925
SPTBN20.924
LZTS30.923
WNK20.922

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
REST-0.56
RAI14-0.52
SEPT10-0.51
FCGR3B-0.51
CST7-0.507
YES1-0.506
WWTR1-0.505
IL18RAP-0.502
TFPI2-0.494
CLEC2B-0.493

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB12364BetrixabanSmall Molecule330942-05-7Approved|InvestigationalTransporter
DB00176FluvoxamineSmall Molecule54739-18-3Approved|InvestigationalTarget
DB00199ErythromycinSmall Molecule114-07-8Approved|InvestigationalTarget
DB00204DofetilideSmall Molecule115256-11-6Approved|InvestigationalTarget
DB00276AmsacrineSmall Molecule51264-14-3Approved|InvestigationalTarget
DB00280DisopyramideSmall Molecule3737-09-5ApprovedTarget
DB00308IbutilideSmall Molecule122647-31-8ApprovedTarget
DB00342TerfenadineSmall Molecule50679-08-8Approved|WithdrawnTarget
DB00346AlfuzosinSmall Molecule81403-80-7Approved|InvestigationalTarget
DB00455LoratadineSmall Molecule79794-75-5Approved|InvestigationalTarget
DB00457PrazosinSmall Molecule19216-56-9ApprovedTarget
DB00458ImipramineSmall Molecule50-49-7ApprovedTarget
DB00472FluoxetineSmall Molecule54910-89-3ApprovedTarget
DB00477ChlorpromazineSmall Molecule50-53-3Approved|InvestigationalTarget
DB00489SotalolSmall Molecule3930-20-9ApprovedTarget
DB00537CiprofloxacinSmall Molecule85721-33-1Approved|InvestigationalTarget
DB00590DoxazosinSmall Molecule74191-85-8ApprovedTarget
DB00604CisaprideSmall Molecule81098-60-4Approved|Investigational|WithdrawnTarget
DB00637AstemizoleSmall Molecule68844-77-9Approved|WithdrawnTarget
DB00661VerapamilSmall Molecule52-53-9ApprovedTarget
DB00675TamoxifenSmall Molecule10540-29-1ApprovedTarget
DB00679ThioridazineSmall Molecule50-52-2Approved|WithdrawnTarget
DB00908QuinidineSmall Molecule56-54-2Approved|InvestigationalTarget
DB01026KetoconazoleSmall Molecule65277-42-1Approved|InvestigationalTarget
DB01035ProcainamideSmall Molecule51-06-9ApprovedTarget
DB01074PerhexilineSmall Molecule6621-47-2Approved|InvestigationalTarget
DB01100PimozideSmall Molecule2062-78-4ApprovedTarget
DB01110MiconazoleSmall Molecule22916-47-8Approved|InvestigationalTarget
DB01118AmiodaroneSmall Molecule1951-25-3Approved|InvestigationalTarget
DB01136CarvedilolSmall Molecule72956-09-3Approved|InvestigationalTarget
DB01142DoxepinSmall Molecule1668-19-5Approved|InvestigationalTarget
DB01149NefazodoneSmall Molecule83366-66-9Approved|WithdrawnTarget
DB01162TerazosinSmall Molecule63590-64-7ApprovedTarget
DB01182PropafenoneSmall Molecule54063-53-5ApprovedTarget
DB01195FlecainideSmall Molecule54143-55-4Approved|WithdrawnTarget
DB01211ClarithromycinSmall Molecule81103-11-9ApprovedTarget
DB01218HalofantrineSmall Molecule69756-53-2ApprovedTarget
DB01244BepridilSmall Molecule64706-54-3Approved|WithdrawnTarget
DB04855DronedaroneSmall Molecule141626-36-0ApprovedTarget
DB04957AzimilideSmall Molecule149908-53-2InvestigationalTarget
DB06144SertindoleSmall Molecule106516-24-9Approved|Investigational|WithdrawnTarget
DB06217VernakalantSmall Molecule794466-70-9Approved|InvestigationalTarget
DB06457TecastemizoleSmall Molecule75970-99-9InvestigationalTarget
DB11090Potassium nitrateSmall Molecule7757-79-1ApprovedTarget
DB11386ChlorobutanolSmall Molecule57-15-8Approved|InvestigationalTarget
DB11633IsavuconazoleSmall Molecule241479-67-4Approved|InvestigationalTarget
DB11642PitolisantSmall Molecule362665-56-3Approved|InvestigationalTarget
ID Drug Name Action PubMed
C5169751-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine results in decreased activity of KCNH2 protein21634396
C0502321,3-ditolylguanidine"1,3-ditolylguanidine results in decreased activity of KCNH2 protein"17460149
C10334518-methoxycoronaridine18-methoxycoronaridine results in decreased activity of KCNH2 protein23707769
C5278322-(2-(3,4-dichlorophenyl)-2,3-dihydro-1H-isoindol-5-ylamino)nicotinic acid"2-(2-(3,4-dichlorophenyl)-2,3-dihydro-1H-isoindol-5-ylamino)nicotinic acid results in increased activity of KCNH2 protein"15976038
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of KCNH2 mRNA"19114083
C5171402-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid"2-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid analog results in increased activity of KCNH2 protein"15976038
C5171402-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid"2-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid inhibits the reaction [Terfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]]"21158687
C5171402-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid"2-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid promotes the reaction [KCNH2 protein results in increased transport of Thallium]"21158687
C5171402-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid"2-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid results in increased activity of KCNH2 protein"15976038
D0000737382-Hydroxypropyl-beta-cyclodextrin2-Hydroxypropyl-beta-cyclodextrin inhibits the reaction [Progesterone results in decreased localization of KCNH2 protein]21525004
C0720303,3'-diethylthiacarbocyanine iodide"3,3'-diethylthiacarbocyanine iodide results in decreased activity of KCNH2 protein"28551711
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl affects the activity of KCNH2 protein"22676973
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of KCNH2 mRNA"18648102
C0884644-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide"4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide results in decreased activity of KCNH2 protein"28551711
C4988264-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in decreased activity of KCNH2 protein23707608
C5860728-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-1-thia-4,8-diazaspiro(4.5)decan-3-one"8-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-1-thia-4,8-diazaspiro(4.5)decan-3-one results in decreased activity of KCNH2 protein"28551711
C5027778,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino(1,2-a)quinoxalin-5(6H)-one"8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino(1,2-a)quinoxalin-5(6H)-one inhibits the reaction [KCNH2 protein results in increased transport of Thallium]"21158687
D000143AcidsAcids inhibits the reaction [azimilide results in decreased activity of KCNH2 protein]15821840
D000143AcidsAcids inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein]15821840
D000143AcidsAcids inhibits the reaction [Quinidine results in decreased activity of KCNH2 protein]15821840
D000255Adenosine TriphosphateAdenosine Triphosphate deficiency results in decreased activity of KCNH2 protein12531891
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of KCNH2 mRNA"19936710
D000404AjmalineAjmaline results in decreased activity of KCNH2 protein15599706|2405256
D000404AjmalineAjmaline results in decreased activity of KCNH2 protein15599706
D000447AldehydesAldehydes results in increased expression of KCNH2 mRNA25014914
C022192alinidinealinidine results in decreased activity of KCNH2 protein28551711
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]12531891
C052036alpidemalpidem results in decreased activity of KCNH2 protein24052561
C010846alverinealverine results in decreased activity of KCNH2 protein28551711
D000547AmantadineAmantadine results in decreased activity of KCNH2 protein21158687
D0157614-Aminopyridine4-Aminopyridine results in decreased activity of KCNH2 protein19915712
D000638AmiodaroneAmiodarone affects the activity of KCNH2 protein22020101
D000638AmiodaroneAmiodarone binds to and results in decreased activity of KCNH2 protein15272206
D000638AmiodaroneAmiodarone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D000638AmiodaroneAmiodarone promotes the reaction [naringenin results in decreased activity of KCNH2 protein]18057881
D000638AmiodaroneAmiodarone results in decreased activity of KCNH2 protein10208308|1123827
D000638Amiodaronenaringenin promotes the reaction [Amiodarone results in decreased activity of KCNH2 protein]18057881
D000638AmiodaronePotassium inhibits the reaction [Amiodarone results in decreased activity of KCNH2 protein]15618689
D000638AmiodaroneAmiodarone results in decreased activity of KCNH2 protein18329740
D000639AmitriptylineAmitriptyline inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D000643Ammonium ChlorideAmmonium Chloride affects the expression of KCNH2 mRNA16483693
C038974amorolfineamorolfine results in decreased activity of KCNH2 protein28551711
C049058amperozideamperozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D000677AmsacrineAmsacrine binds to and results in decreased activity of KCNH2 protein15148258
C475726APETx1, Anthopleura elegantissima"APETx1, Anthopleura elegantissima affects the activity of KCNH2 protein"22972919
D001073AprindineAprindine results in decreased activity of KCNH2 protein28551711
C006615aprofenaprofen results in decreased activity of KCNH2 protein28551711
D000068180AripiprazoleAripiprazole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D000068180AripiprazoleAripiprazole results in decreased activity of KCNH2 protein28551711
D001151ArsenicArsenic affects the expression of KCNH2 mRNA18414638
C006632arsenic trioxidearsenic trioxide results in decreased expression of KCNH2 protein22853924
C006632arsenic trioxideLy-364947 inhibits the reaction [arsenic trioxide results in decreased expression of KCNH2 protein]22853924
C006632arsenic trioxide[arsenic trioxide results in increased expression of SP1 protein] which results in increased expression of KCNH2 mRNA23103450
C006632arsenic trioxide[arsenic trioxide results in increased expression of SP1 protein] which results in increased expression of KCNH2 protein23103450
C006632arsenic trioxidearsenic trioxide results in decreased activity of KCNH2 protein25107562
C006632arsenic trioxidearsenic trioxide results in decreased expression of and affects the localization of and results in decreased activity of KCNH2 protein25395240
C006632arsenic trioxidearsenic trioxide results in decreased expression of KCNH2 protein22977528
C006632arsenic trioxidearsenic trioxide results in decreased localization of KCNH2 protein15213294|2310345
C006632arsenic trioxidearsenic trioxide results in increased degradation of KCNH2 protein28521025
C006632arsenic trioxidearsenic trioxide results in increased expression of KCNH2 mRNA15070760
C006632arsenic trioxideAstemizole inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]28521025
C006632arsenic trioxidebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]28521025
C006632arsenic trioxidefexofenadine inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]28521025
C006632arsenic trioxidematrine inhibits the reaction [arsenic trioxide results in decreased localization of KCNH2 protein]23103450
C006632arsenic trioxideMIR21 mRNA promotes the reaction [arsenic trioxide results in decreased expression of KCNH2 protein]25395240
C006632arsenic trioxideMIR23A mRNA promotes the reaction [arsenic trioxide results in decreased expression of and affects the localization of and results in decreased activity of KCNH2 protein]25395240
C006632arsenic trioxideoxymatrine inhibits the reaction [arsenic trioxide results in decreased localization of KCNH2 protein]23103450
C006632arsenic trioxideRanolazine inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]28521025
C006632arsenic trioxideresveratrol inhibits the reaction [arsenic trioxide results in decreased activity of KCNH2 protein]25107562
C006632arsenic trioxidearsenic trioxide affects the activity of KCNH2 protein14691044
C006632arsenic trioxidearsenic trioxide results in decreased expression of and affects the activity of KCNH2 protein28768059
C006632arsenic trioxidearsenic trioxide results in decreased expression of KCNH2 mRNA25395240
C006632arsenic trioxidearsenic trioxide results in decreased expression of KCNH2 protein25107562
C006632arsenic trioxideCatechin inhibits the reaction [arsenic trioxide results in decreased expression of and affects the activity of KCNH2 protein]28768059
C006632arsenic trioxideresveratrol inhibits the reaction [arsenic trioxide results in decreased expression of KCNH2 protein]25107562
D016589AstemizoleAstemizole binds to and results in decreased activity of KCNH2 protein12388285
D016589AstemizoleAstemizole binds to and results in decreased activity of KCNH2 protein14678746
D016589AstemizoleAstemizole affects the localization of KCNH2 protein mutant form10531299|1174192
D016589AstemizoleAstemizole binds to and results in decreased activity of KCNH2 protein10376921|1170545
D016589AstemizoleAstemizole binds to KCNH2 gene polymorphism18701618
D016589AstemizoleAstemizole binds to KCNH2 protein15272206|1870161
D016589AstemizoleAstemizole inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]28521025
D016589AstemizoleAstemizole inhibits the reaction [Digoxin results in decreased activity of KCNH2 protein]19139152
D016589AstemizoleAstemizole inhibits the reaction [Digoxin results in decreased metabolism of KCNH2 protein modified form]19139152
D016589AstemizoleAstemizole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D016589AstemizoleAstemizole results in decreased activity of KCNH2 protein10422790|1082846
D016589Astemizoledofetilide analog inhibits the reaction [Astemizole binds to KCNH2 protein]24200993
D016589AstemizoleHydrogen Peroxide inhibits the reaction [Astemizole results in decreased activity of KCNH2 protein mutant form]10828461
D016589AstemizolePotassium promotes the reaction [Astemizole binds to KCNH2 protein]24200993
D016589AstemizoleAstemizole results in decreased activity of KCNH2 protein16723379
D016589AstemizoleAstemizole results in decreased activity of KCNH2 protein11040061
D001280AtrazineAtrazine results in increased expression of KCNH2 mRNA22378314
D001376AzaperoneAzaperone results in decreased activity of KCNH2 protein28551711
C406592azaspiracidazaspiracid binds to and results in decreased activity of KCNH2 protein22856456
C520447azaspiracid-2azaspiracid-2 results in decreased activity of KCNH2 protein23934164
C020976azelastineazelastine results in decreased activity of KCNH2 protein28551711
C086123azimilideAcids inhibits the reaction [azimilide results in decreased activity of KCNH2 protein]15821840
C086123azimilideazimilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]18057881
C086123azimilideazimilide results in decreased activity of KCNH2 protein15821840|1696044
C086123azimilidenaringenin promotes the reaction [azimilide results in decreased activity of KCNH2 protein]18057881
C086123azimilidePotassium inhibits the reaction [azimilide results in decreased activity of KCNH2 protein]16960444
C425305BeKm-1 toxinBeKm-1 toxin results in decreased activity of KCNH2 protein21158687|2120591
D001535BenactyzineBenactyzine results in decreased activity of KCNH2 protein28551711
C001584benfluorexbenfluorex results in decreased activity of KCNH2 protein28551711
C005298benoxinatebenoxinate results in decreased activity of KCNH2 protein28551711
D001544BenperidolBenperidol results in decreased activity of KCNH2 protein28551711
D001548Benzalkonium CompoundsBenzalkonium Compounds results in decreased activity of KCNH2 protein24052561
D001558BenzethoniumBenzethonium results in decreased activity of KCNH2 protein21362439|2331361
D001558Benzethonium[Benzethonium results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D001590BenztropineBenztropine results in decreased activity of KCNH2 protein28551711
D001591BenzydamineBenzydamine results in decreased activity of KCNH2 protein28551711
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]28521025
D015764BepridilBepridil results in decreased activity of KCNH2 protein14975710
D015764BepridilBepridil binds to and results in decreased activity of KCNH2 protein15272206
D015764BepridilBepridil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D015764BepridilBepridil results in decreased activity of KCNH2 protein15671647|2405256
D047392beta-Cyclodextrinsbeta-Cyclodextrins analog inhibits the reaction [Cisapride results in decreased activity of KCNH2 protein]17513944
D047392beta-Cyclodextrinsbeta-Cyclodextrins analog inhibits the reaction [E 4031 results in decreased activity of KCNH2 protein]17513944
D047392beta-Cyclodextrinsbeta-Cyclodextrins analog inhibits the reaction [Terfenadine results in decreased activity of KCNH2 protein]17513944
D047392beta-Cyclodextrinsbeta-Cyclodextrins analog results in decreased activity of KCNH2 protein17513944
D001621BetahistineBetahistine results in decreased activity of KCNH2 protein28551711
C031906bifemelanebifemelane results in decreased activity of KCNH2 protein28551711
C006780bisphenol Abisphenol A results in decreased expression of KCNH2 mRNA25181051
C036007bopindololbopindolol results in decreased activity of KCNH2 protein28551711
D001977BrompheniramineBrompheniramine results in decreased activity of KCNH2 protein17010640|1751645
D001964BromhexineBromhexine results in decreased activity of KCNH2 protein28551711
C066635bromocyclenbromocyclen results in decreased activity of KCNH2 protein28551711
C006820bromperidolbromperidol results in decreased activity of KCNH2 protein28551711
C024307bucindololbucindolol results in decreased activity of KCNH2 protein28551711
C046894buclizinebuclizine results in decreased activity of KCNH2 protein28551711
C100222bunamidinebunamidine results in decreased activity of KCNH2 protein28551711
D002069ButaclamolButaclamol results in decreased activity of KCNH2 protein28551711
C017125butoconazolebutoconazole results in decreased activity of KCNH2 protein28551711
C018475butyraldehydebutyraldehyde results in increased expression of KCNH2 mRNA26079696
D019256Cadmium ChlorideCadmium Chloride results in increased methylation of KCNH2 promoter22457795
D002118CalciumNimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium]11040061
C004644camylofinecamylofine results in decreased activity of KCNH2 protein28551711
C018861carbetapentanecarbetapentane results in decreased activity of KCNH2 protein19034038
C004649carbinoxaminecarbinoxamine results in decreased activity of KCNH2 protein28551711
D002330CarmustineCarmustine results in decreased expression of KCNH2 mRNA15980968
C043211carvedilolcarvedilol affects the activity of KCNH2 protein22020101
C043211carvedilolcarvedilol results in decreased activity of KCNH2 protein11164846|1631485
C054133casticincasticin results in decreased expression of KCNH2 mRNA28444820
D002392CatechinCatechin inhibits the reaction [arsenic trioxide results in decreased expression of and affects the activity of KCNH2 protein]28768059
D002392CatechinCatechin results in increased expression of and affects the activity of KCNH2 protein28768059
D015313CefotetanCefotetan results in decreased activity of KCNH2 protein28551711
C006947cepharanthinecepharanthine results in decreased activity of KCNH2 protein28551711
C012817cetalkonium chloridecetalkonium chloride results in decreased activity of KCNH2 protein28551711
C568619cetyldimethylethylammoniumcetyldimethylethylammonium results in decreased activity of KCNH2 protein28551711
C016300chloramine-Tchloramine-T results in increased oxidation of and results in decreased activity of KCNH2 protein17624316
D002724ChlorobutanolChlorobutanol binds to and results in decreased activity of KCNH2 protein20071423
D002724ChlorobutanolChlorobutanol promotes the reaction [Methadone results in decreased activity of KCNH2 protein]14527710
D002724ChlorobutanolChlorobutanol promotes the reaction [Terfenadine binds to and results in decreased activity of KCNH2 protein]20071423
D002724ChlorobutanolChlorobutanol results in decreased activity of KCNH2 protein14527710
D002724ChlorobutanolTerfenadine promotes the reaction [Chlorobutanol binds to and results in decreased activity of KCNH2 protein]20071423
D002725ChloroformChloroform results in decreased activity of KCNH2 protein22024336
D002725ChloroformChloroform results in decreased activity of KCNH216647228
D002744ChlorpheniramineChlorpheniramine affects the activity of KCNH2 protein16278312
D002744ChlorpheniramineChlorpheniramine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D002744ChlorpheniramineChlorpheniramine results in decreased activity of KCNH2 protein19885040
D002746ChlorpromazineChlorpromazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D002746ChlorpromazineChlorpromazine results in decreased activity of KCNH2 protein15071359|2405256
D002746ChlorpromazineChlorpromazine results in decreased activity of KCNH212788816
D002749ChlorprothixeneChlorprothixene results in decreased activity of KCNH2 protein28551711
D002784CholesterolCholesterol results in decreased localization of KCNH2 protein21525004
C011585ciclopiroxciclopirox inhibits the reaction [Terfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]]21158687
C011585ciclopiroxciclopirox promotes the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C032151cifenlinecifenline results in decreased activity of KCNH2 protein24052561
D000069449Cinacalcet HydrochlorideCinacalcet Hydrochloride results in decreased activity of KCNH2 protein28551711
C010086cinchoninecinchonine results in decreased activity of KCNH2 protein28551711
D020117CisaprideCisapride binds to and results in decreased activity of KCNH2 protein12388285
D020117CisaprideCisapride results in decreased activity of KCNH2 protein14975710
D020117CisaprideCisapride binds to and results in decreased activity of KCNH2 protein14678746
D020117Cisapridebeta-Cyclodextrins analog inhibits the reaction [Cisapride results in decreased activity of KCNH2 protein]17513944
D020117CisaprideCisapride affects the localization of KCNH2 protein mutant form10531299|1174192
D020117CisaprideCisapride binds to and results in decreased activity of KCNH2 protein11005845|1238828
D020117CisaprideCisapride binds to KCNH2 protein18701618|1926073
D020117CisaprideCisapride inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D020117CisaprideCisapride results in decreased activity of KCNH2 protein11741928|1530620
D020117CisaprideCisapride inhibits the reaction [KCNH2 protein results in increased transport of Thallium]20208034
D020117CisaprideCisapride results in decreased activity of KCNH2 protein12052668|2219805
D017291ClarithromycinClarithromycin results in decreased activity of KCNH2 protein24052561
D017291Clarithromycin[KCNE2 protein mutant form binds to KCNH2 protein] which results in increased susceptibility to Clarithromycin10219239
C014417cleboprideclebopride results in decreased activity of KCNH2 protein28551711
D002974ClemastineClemastine results in decreased activity of KCNH2 protein28551711
C017135clobutinolclobutinol results in decreased activity of KCNH2 protein19034038|2855171
D002991ClofazimineClofazimine results in decreased activity of KCNH2 protein28551711
C010432clofedanolclofedanol results in decreased activity of KCNH2 protein28551711
C004687clofexamideclofexamide results in decreased activity of KCNH2 protein28551711
D002997ClomipramineClomipramine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D003006ClopenthixolClopenthixol results in decreased activity of KCNH2 protein28551711
C040282cloperastinecloperastine results in decreased activity of KCNH2 protein28551711
C084602clothiapineclothiapine results in decreased activity of KCNH2 protein28551711
D003022ClotrimazoleClotrimazole results in decreased activity of KCNH2 protein28551711
D003024ClozapineClozapine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C018021cobaltous chloridecobaltous chloride results in decreased expression of KCNH2 mRNA22941251
D003061CodeineCodeine results in decreased activity of KCNH2 protein19034038
D005576Colforsin[[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]19419905
D003345CorticosteroneCorticosterone results in increased expression of KCNH2 mRNA18835572
C551994crizotinibcrizotinib results in decreased activity of KCNH2 protein23707608
D003474CurcuminCurcumin results in decreased activity of KCNH2 protein28551711
C028457cyamemazinecyamemazine metabolite results in decreased activity of KCNH2 protein18957172
C028457cyamemazinecyamemazine results in decreased activity of KCNH2 protein16494862
C533908cyamemazine sulfoxidecyamemazine sulfoxide results in decreased activity of KCNH2 protein18957172
D016572CyclosporineCyclosporine results in decreased methylation of KCNH2 promoter27989131
C032939cyclovirobuxine Dcyclovirobuxine D results in decreased activity of KCNH2 protein21497594
D003620DantroleneDantrolene results in decreased activity of KCNH2 protein24052561
C101207darifenacindarifenacin results in decreased activity of KCNH2 protein28551711
D003630DaunorubicinDaunorubicin results in decreased expression of KCNH2 mRNA26537877|2894005
D003634DDTDDT results in decreased activity of KCNH2 protein28551711
C042438decominoldecominol results in decreased activity of KCNH2 protein28551711
D015255IdarubicinIdarubicin results in decreased activity of KCNH2 protein24052561
C037293denopaminedenopamine results in decreased activity of KCNH2 protein28551711
D003847Deoxyglucose[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein12531891
D003847DeoxyglucoseDeoxyglucose inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]12531891
D003847DeoxyglucoseDeoxyglucose promotes the reaction [Glucose deficiency results in decreased activity of KCNH2 protein]12531891
D003847DeoxyglucoseDeoxyglucose results in decreased activity of KCNH2 protein12531891
D003847DeoxyglucosePyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein]12531891
D003891DesipramineDesipramine results in decreased activity of KCNH2 protein20211602|2405256
C121345desloratadinedesloratadine results in decreased activity of KCNH2 protein28551711
C040463desmethylastemizoledesmethylastemizole binds to and results in decreased activity of KCNH2 protein10376921
C015121dexbrompheniraminedexbrompheniramine results in decreased activity of KCNH2 protein28551711
D003909DexetimideDexetimide results in decreased activity of KCNH2 protein28551711
C042577diallyl trisulfidediallyl trisulfide results in decreased activity of KCNH2 protein23272117
C042577diallyl trisulfidediallyl trisulfide results in decreased expression of and results in decreased activity of KCNH2 protein24504171
C025079diazolinediazoline results in decreased activity of KCNH2 protein28551711
C100220dibenzheptropinedibenzheptropine results in decreased activity of KCNH2 protein28551711
D003992DibucaineDibucaine results in decreased activity of KCNH2 protein28551711
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of KCNH2 mRNA21266533
D002945CisplatinCisplatin results in decreased expression of KCNH2 mRNA27594783
D002945CisplatinCisplatin results in increased expression of KCNH222020779
D002945CisplatinKCNH2 results in increased susceptibility to Cisplatin22020779
C027118didecyldimethylammoniumdidecyldimethylammonium results in decreased activity of KCNH2 protein21362439|2855171
C027118didecyldimethylammonium[didecyldimethylammonium results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of KCNH2 mRNA25242112
D004077DigoxinAstemizole inhibits the reaction [Digoxin results in decreased activity of KCNH2 protein]19139152
D004077DigoxinAstemizole inhibits the reaction [Digoxin results in decreased metabolism of KCNH2 protein modified form]19139152
D004077DigoxinDigoxin results in decreased activity of KCNH2 protein19139152
D004077DigoxinDigoxin results in decreased expression of KCNH2 protein modified form19139152
D004077DigoxinKCNH2 gene affects the susceptibility to Digoxin19139152
D004077DigoxinSodium deficiency inhibits the reaction [Digoxin results in decreased expression of KCNH2 protein]19139152
D002117CalcitriolCalcitriol results in increased expression of KCNH2 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of KCNH2 mRNA21592394
C009146dimethisoquindimethisoquin results in decreased activity of KCNH2 protein28551711
D004155DiphenhydramineDiphenhydramine binds to and results in decreased activity of KCNH2 protein14678746
C027773diphenylguanidinediphenylguanidine results in decreased activity of KCNH2 protein21362439
C027773diphenylguanidine[diphenylguanidine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
C009871diphenylpyralinediphenylpyraline results in decreased activity of KCNH2 protein28551711
D004206DisopyramideDisopyramide binds to and results in decreased activity of KCNH2 protein15272206
D004206DisopyramideDisopyramide results in decreased activity of KCNH2 protein18724381|2855171
D004225DithiazanineDithiazanine results in decreased activity of KCNH2 protein28551711
D004280DobutamineDobutamine results in decreased activity of KCNH2 protein24052561
C063533dofetilideAcids inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein]15821840
C063533dofetilidedofetilide analog inhibits the reaction [Astemizole binds to KCNH2 protein]24200993
C063533dofetilidedofetilide analog inhibits the reaction [dofetilide binds to KCNH2 protein]24200993
C063533dofetilidedofetilide binds to and results in decreased activity of KCNH2 protein15961988|2007142
C063533dofetilidedofetilide binds to KCNH2 protein15272206|1870161
C063533dofetilidedofetilide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C063533dofetilidedofetilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]18057881
C063533dofetilidedofetilide results in decreased activity of KCNH2 protein10828461|1582184
C063533dofetilideHydrogen Peroxide inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein mutant form]10828461
C063533dofetilidenaringenin promotes the reaction [dofetilide results in decreased activity of KCNH2 protein]18057881
C063533dofetilidePotassium affects the reaction [dofetilide analog inhibits the reaction [dofetilide binds to KCNH2 protein]]24200993
C063533dofetilidePotassium inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein]16960444
C063533dofetilidePotassium promotes the reaction [dofetilide binds to KCNH2 protein]24200993
C063533dofetilide[Terfenadine co-treated with dofetilide] binds to and results in decreased activity of KCNH2 protein20071423
C063533dofetilidedofetilide results in decreased activity of KCNH2 protein17376289
C063533dofetilidedofetilide binds to KCNH2 protein21634430
C060344dolasetrondolasetron results in decreased activity of KCNH2 protein28551711
C007556domiphendomiphen results in decreased activity of KCNH2 protein21362439|2855171
C007556domiphen[domiphen results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D004294DomperidoneDomperidone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D004294DomperidoneDomperidone results in decreased activity of KCNH2 protein15640612|2855171
D004294DomperidoneKCNH2 gene SNP affects the susceptibility to Domperidone21063774
D004316DoxepinDoxepin inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D004317DoxorubicinDoxorubicin results in decreased expression of KCNH2 mRNA26537877|2894005
D004317DoxorubicinErythromycin affects the reaction [KCNH2 protein results in decreased susceptibility to Doxorubicin]16086867
D004317DoxorubicinKCNH2 protein results in decreased susceptibility to Doxorubicin16086867
D004317DoxorubicinDoxorubicin results in decreased expression of KCNH2 mRNA19915844
C118667dronedaronedronedarone results in decreased activity of KCNH2 protein15618689
C118667dronedaronePotassium inhibits the reaction [dronedarone results in decreased activity of KCNH2 protein]15618689
D004329DroperidolDroperidol binds to and results in decreased activity of KCNH2 protein14678746
D004329DroperidolDroperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D004329DroperidolDroperidol results in decreased activity of KCNH2 protein16757186|2855171
D000068736Duloxetine HydrochlorideDuloxetine Hydrochloride results in decreased activity of KCNH2 protein28551711
D000068538DutasterideDutasteride results in decreased activity of KCNH2 protein28551711
C100063dycloninedyclonine results in decreased activity of KCNH2 protein28551711
C063968E 4031E 4031 results in decreased activity of KCNH2 protein14975710
C063968E 4031E 4031 binds to and results in decreased activity of KCNH2 protein14678746
C063968E 4031beta-Cyclodextrins analog inhibits the reaction [E 4031 results in decreased activity of KCNH2 protein]17513944
C063968E 4031E 4031 affects the localization of KCNH2 protein mutant form11741928
C063968E 4031E 4031 binds to and results in decreased activity of KCNH2 protein15272206
C063968E 4031E 4031 binds to KCNH2 protein19260734
C063968E 4031E 4031 inhibits the reaction [fexofenadine results in increased activity of KCNH2 protein mutant form]12070109
C063968E 4031E 4031 inhibits the reaction [Flufenamic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]]12359267
C063968E 4031E 4031 inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
C063968E 4031E 4031 inhibits the reaction [Niflumic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]]12359267
C063968E 4031E 4031 results in decreased activity of [KCNE2 protein binds to KCNH2 protein]10219239
C063968E 4031E 4031 results in decreased activity of KCNH2 protein11741928|1235926
C063968E 4031E 4031 results in increased activity of KCNH2 protein mutant form10531299
C063968E 4031E 4031 results in increased glycosylation of and affects the localization of KCNH2 protein mutant form10531299
C063968E 4031[KCNE2 protein binds to KCNH2 protein] which results in increased susceptibility to E 403110219239
C063968E 4031E 4031 inhibits the reaction [Progesterone results in decreased localization of KCNH2 protein]21525004
C063968E 4031E 4031 results in decreased activity of KCNH2 protein22198052|2326164
C058249ebastineebastine results in decreased activity of KCNH2 protein28551711
C016422eburnamonineeburnamonine results in decreased activity of KCNH2 protein28551711
D004464EconazoleEconazole results in decreased activity of KCNH2 protein21362439
D004464Econazole[Econazole results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
C115647eletriptaneletriptan results in decreased activity of KCNH2 protein28551711
C058083eliprodileliprodil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
C043345emedastineemedastine results in decreased activity of KCNH2 protein28551711
C070189(endo-N-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2,3-dihydro-3-isopropyl-2-oxo-1H-benzimidazol-1-carboxamide"(endo-N-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2,3-dihydro-3-isopropyl-2-oxo-1H-benzimidazol-1-carboxamide results in decreased activity of KCNH2 protein"28552773
C053090epinastineepinastine results in decreased activity of KCNH2 protein28551711
C118951ergotoxin, Centruroides noxius"ergotoxin, Centruroides noxius binds to and results in decreased activity of KCNH2 protein"20071423
C118951ergotoxin, Centruroides noxius"[Terfenadine co-treated with ergotoxin, Centruroides noxius] binds to and results in decreased activity of KCNH2 protein"20071423
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride affects the activity of KCNH2 protein23707608
D004917ErythromycinErythromycin affects the reaction [KCNH2 protein results in decreased susceptibility to Doxorubicin]16086867
D004917ErythromycinErythromycin binds to and results in decreased activity of KCNH2 protein15272206
D004917ErythromycinErythromycin binds to KCNH2 protein18701618
D004917ErythromycinErythromycin results in decreased activity of KCNH2 protein24052561
D000431EthanolEthanol results in decreased activity of KCNH2 protein28284858
C007639ethaverineethaverine results in decreased activity of KCNH2 protein28551711
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of KCNH2 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of KCNH2 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KCNH2 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of KCNH2 mRNA17557909
C101866ezogabineezogabine affects the activity of KCNH2 protein28641963
C070475fananserinfananserin results in decreased activity of KCNH2 protein28551711
C017309febantelfebantel results in decreased activity of KCNH2 protein28551711
D005275FendilineFendiline results in decreased activity of KCNH2 protein28551711
C048314fenoverinefenoverine results in decreased activity of KCNH2 protein28551711
D005283FentanylFentanyl results in decreased activity of KCNH2 protein28551711
C093230fexofenadineE 4031 inhibits the reaction [fexofenadine results in increased activity of KCNH2 protein mutant form]12070109
C093230fexofenadinefexofenadine inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]28521025
C093230fexofenadinefexofenadine results in increased activity of KCNH2 protein mutant form12070109
D000068876Fingolimod HydrochlorideFingolimod Hydrochloride results in decreased activity of KCNH2 protein25223691
D005419FlavonoidsFlavonoids results in increased expression of KCNH2 mRNA18035473
C004811flazoloneflazolone results in decreased activity of KCNH2 protein28551711
D005424FlecainideFlecainide binds to and results in decreased activity of KCNH2 protein15272206
D005424FlecainideFlecainide results in decreased activity of KCNH2 protein24052561
D005439Flufenamic AcidE 4031 inhibits the reaction [Flufenamic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]]12359267
D005439Flufenamic AcidFlufenamic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]12359267
D019793FluoresceinFluorescein results in decreased activity of KCNH2 protein28551711
D005473FluoxetineFluoxetine affects the localization of KCNH2 protein16967046
D005473FluoxetineFluoxetine binds to and results in decreased activity of KCNH2 protein15272206
D005473FluoxetineFluoxetine inhibits the reaction [KCNH2 protein results in increased transport of Potassium]11805215
D005473FluoxetineFluoxetine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D005473FluoxetineFluoxetine results in decreased activity of KCNH2 protein16967046|2405256
D005473FluoxetineKCNH2 protein affects the susceptibility to Fluoxetine16967046
D005475FlupenthixolFlupenthixol results in decreased activity of KCNH2 protein28551711
D005479FlurazepamFlurazepam results in decreased activity of KCNH2 protein28551711
D016666FluvoxamineFluvoxamine binds to and results in decreased activity of KCNH2 protein20071423
D016666FluvoxamineFluvoxamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D016666FluvoxamineFluvoxamine results in decreased activity of KCNH2 protein24052561
D016666Fluvoxamine[Terfenadine co-treated with Fluvoxamine] binds to and results in decreased activity of KCNH2 protein20071423
C100275fomocainfomocain results in decreased activity of KCNH2 protein28551711
D000068759Formoterol FumarateFormoterol Fumarate results in decreased activity of KCNH2 protein28551711
C040029gabapentingabapentin results in decreased activity of KCNH2 protein15716081
C001277geldanamycingeldanamycin affects the localization of KCNH2 protein12775586
C001277geldanamycingeldanamycin inhibits the reaction [KCNH2 protein binds to HSP90AA1 protein]12775586
C001277geldanamycingeldanamycin results in decreased activity of KCNH2 protein12775586|2405256
C001277geldanamycingeldanamycin results in decreased expression of KCNH2 protein modified form12775586
C001277geldanamycingeldanamycin results in increased degradation of KCNH2 protein12775586
D005840Gentian VioletGentian Violet results in decreased activity of KCNH2 protein28551711
C442759ginsenoside Rb1ginsenoside Rb1 affects the activity of KCNH2 protein15842772
C055328ginsenoside Rfginsenoside Rf affects the activity of KCNH2 protein15842772
C035054ginsenoside Rg1ginsenoside Rg1 affects the activity of KCNH2 protein15842772
D005947Glucosealpha-Tocopherol inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]12531891
D005947Glucose[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein12531891
D005947GlucoseDeoxyglucose inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]12531891
D005947GlucoseDeoxyglucose promotes the reaction [Glucose deficiency results in decreased activity of KCNH2 protein]12531891
D005947GlucoseGlucose deficiency results in decreased activity of KCNH2 protein12531891
D005947GlucoseGlucose results in decreased activity of KCNH2 protein12531891
D005947Glucosemanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]12531891
D005947GlucosePyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein]12531891
D005947GlucoseSodium Cyanide inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]12531891
D005905GlyburideGlyburide results in decreased activity of KCNH2 protein24052561
C105771GR 103691GR 103691 results in decreased activity of KCNH2 protein28551711
D006096GramicidinGramicidin results in decreased expression of KCNH2 protein modified form19139152
D006096GramicidinPotassium inhibits the reaction [Gramicidin results in decreased expression of KCNH2 protein modified form]19139152
D006096GramicidinRubidium inhibits the reaction [Gramicidin results in decreased expression of KCNH2 protein modified form]19139152
C075375grepafloxacingrepafloxacin results in decreased activity of KCNH2 protein21158687
C023768halofantrinehalofantrine results in decreased activity of KCNH2 protein28551711
D006220HaloperidolHaloperidol binds to and results in decreased activity of KCNH2 protein14678746
D006220HaloperidolHaloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D006220HaloperidolHaloperidol results in decreased activity of KCNH2 protein15671647|1627831
D006220HaloperidolHaloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]20208034
D006590HexetidineHexetidine results in decreased activity of KCNH2 protein28551711
C060446homosalatehomosalate results in decreased activity of KCNH2 protein28551711
D017313FenretinideFenretinide results in decreased expression of KCNH2 mRNA28973697
D017313FenretinideFenretinide results in increased expression of KCNH2 mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [Astemizole results in decreased activity of KCNH2 protein mutant form]10828461
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein mutant form]10828461
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [Terfenadine results in decreased activity of KCNH2 protein mutant form]10828461
D006919HydroxyzineHydroxyzine results in decreased activity of KCNH2 protein19057127
C026777ICI 118551ICI 118551 results in decreased activity of KCNH2 protein16314852
C026777ICI 118551ICI 118551 results in decreased activity of [KCNH2 protein binds to KCNH2 protein]15679475
C010739ifenprodilifenprodil results in decreased activity of KCNH2 protein17460149|2855171
C010739ifenprodilSM 21 promotes the reaction [ifenprodil results in decreased activity of KCNH2 protein]17460149
D007099ImipramineImipramine binds to and results in decreased activity of KCNH2 protein15272206
D007099ImipramineImipramine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D007099ImipramineImipramine results in decreased activity of KCNH2 protein24052561
D007099ImipramineImipramine results in decreased localization of KCNH2 protein21525004
D020367IofetamineIofetamine results in decreased activity of KCNH2 protein28551711
C018986ipriflavoneipriflavone results in decreased activity of KCNH2 protein28551711
C061126iron(III)-ascorbic acid complex[iron(III)-ascorbic acid complex results in increased abundance of Reactive Oxygen Species] affects the reaction [KCNH2 protein affects the transport of Potassium]9326673
C061126iron(III)-ascorbic acid complex[iron(III)-ascorbic acid complex results in increased abundance of Reactive Oxygen Species] which affects the activity of KCNH2 protein9326673
C058392isamoltaneisamoltane results in decreased activity of KCNH2 protein28551711
D0150561-Methyl-3-isobutylxanthine[[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]19419905
C020382isoconazoleisoconazole results in decreased activity of KCNH2 protein28551711
C088408ivabradineivabradine results in decreased activity of KCNH2 protein28551711
D007654KetoconazoleKCNH2 protein mutant form results in decreased susceptibility to Ketoconazole16542653
D007654KetoconazoleKetoconazole affects the activity of KCNH2 protein mutant form17965736
D007654KetoconazoleKetoconazole affects the localization of KCNH217965736
D007654KetoconazoleKetoconazole affects the localization of KCNH2 protein mutant form17965736
D007654KetoconazoleKetoconazole binds to and results in decreased activity of KCNH2 protein15272206
D007654KetoconazoleKetoconazole results in decreased activity of KCNH217965736
D007654KetoconazoleKetoconazole results in decreased activity of KCNH2 protein16542653|2405256
D007654KetoconazoleTerfenadine promotes the reaction [Ketoconazole results in decreased activity of KCNH2 protein]9694927
C087257L 706000L 706000 binds to and results in decreased activity of KCNH2 protein12388285
C087257L 706000L 706000 binds to and results in decreased activity of KCNH2 protein11005845|1238828
C047781lamotriginelamotrigine results in decreased activity of KCNH2 protein15716081
C477361LAQ824LAQ824 results in decreased activity of KCNH2 protein21650221
C100204lenperonelenperone results in decreased activity of KCNH2 protein28551711
C017901levomepromazine maleatelevomepromazine maleate results in decreased activity of KCNH2 protein28551711
D008012LidocaineLidocaine results in decreased activity of KCNH2 protein24052561
D008013LidoflazineLidoflazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D008013LidoflazineLidoflazine results in decreased activity of KCNH2 protein16278312|2855171
C100041lifibratelifibrate results in decreased activity of KCNH2 protein28551711
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of KCNH2 mRNA"24972896
C470235liranaftateliranaftate results in decreased activity of KCNH2 protein28551711
D008120LobelineLobeline results in decreased activity of KCNH2 protein28551711
D008127LofepramineLofepramine results in decreased activity of KCNH2 protein28551711
C052424lomerizinelomerizine results in decreased activity of KCNH2 protein28551711
D017336LoratadineLoratadine affects the activity of KCNH2 protein16278312
D017336LoratadineLoratadine binds to and results in decreased activity of KCNH2 protein11705456|9658196
D017336LoratadineLoratadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D017336LoratadineLoratadine results in decreased activity of KCNH2 protein10604956
D008148LovastatinLovastatin affects the activity of KCNH2 protein16278312
D008152LoxapineLoxapine results in decreased activity of KCNH2 protein28551711
C520284Ly-364947Ly-364947 inhibits the reaction [arsenic trioxide results in decreased expression of KCNH2 protein]22853924
C005095malachite greenmalachite green results in decreased activity of KCNH2 protein21362439
C005095malachite green[malachite green results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]12531891
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [TNF protein results in decreased activity of KCNH2 protein]14973143
C054218manidipinemanidipine results in decreased activity of KCNH2 protein28551711
D008376MaprotilineMaprotiline inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C034244matrinematrine inhibits the reaction [arsenic trioxide results in decreased localization of KCNH2 protein]23103450
C034244matrinematrine results in increased expression of and results in increased activity of KCNH2 protein23103450
C005096mebeverinemebeverine results in decreased activity of KCNH2 protein28551711
D015767MefloquineMefloquine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D015767MefloquineMefloquine results in decreased activity of KCNH2 protein28551711
C100190mepazinemepazine results in decreased activity of KCNH2 protein28551711
D008627Mercuric ChlorideMercuric Chloride results in decreased activity of KCNH2 protein11669488
D008628MercuryMercury results in increased expression of KCNH2 mRNA16823088
D008653MesoridazineMesoridazine results in decreased activity of KCNH2 protein17042915
D008691MethadoneChlorobutanol promotes the reaction [Methadone results in decreased activity of KCNH2 protein]14527710
D008691MethadoneMethadone results in decreased activity of KCNH2 protein14527710
D008692Methadyl AcetateMethadyl Acetate inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C044642methdilazinemethdilazine results in decreased activity of KCNH2 protein28551711
D008719MethiothepinMethiothepin results in decreased activity of KCNH2 protein28551711
C005111methixenemethixene results in decreased activity of KCNH2 protein28551711
D003915DextromethorphanDextromethorphan results in decreased activity of KCNH2 protein19034038
D007050IbogaineIbogaine results in decreased activity of KCNH2 protein23707769|2430719
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of KCNH2 mRNA28001369
C008493methylselenic acidmethylselenic acid results in increased expression of KCNH2 mRNA18548127
D008787MetoclopramideMetoclopramide results in decreased activity of KCNH2 protein15640612
D008790MetoprololMetoprolol results in decreased activity of KCNH2 protein16314852
D008790MetoprololMetoprolol results in decreased activity of [KCNH2 protein binds to KCNH2 protein]15679475
D008801MexiletineMexiletine results in decreased activity of KCNH2 protein24052561
D020748MibefradilMibefradil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D020748MibefradilMibefradil results in decreased activity of KCNH2 protein28551711
D008825MiconazoleMiconazole results in decreased activity of KCNH2 protein28551711
C103741mitemcinalmitemcinal metabolite results in decreased activity of KCNH2 protein17785939
C103741mitemcinalmitemcinal results in decreased activity of KCNH2 protein17785939
D008942MitoxantroneMitoxantrone results in decreased expression of KCNH2 mRNA26537877|2894005
C001801mitragyninemitragynine binds to and results in decreased activity of KCNH2 protein27260674
C001801mitragyninemitragynine results in decreased expression of KCNH2 protein27260674
C076170mizolastinemizolastine results in decreased activity of KCNH2 protein11082114|2855171
C035359monordenmonorden results in decreased activity of KCNH2 protein12775586
C035359monordenmonorden results in decreased expression of KCNH2 protein modified form12775586
C104727moxifloxacinmoxifloxacin results in decreased activity of KCNH2 protein24052561|2755391
D009151Mustard GasMustard Gas affects the expression of KCNH2 mRNA15651846
C531033N-(1-(2,3-dimethoxyphenyl)-4-methyl-3-penten-1-yl)-1-(5-bromofurfuryl)-1-piperidyl-4-amine"KCNH2 protein results in increased susceptibility to N-(1-(2,3-dimethoxyphenyl)-4-methyl-3-penten-1-yl)-1-(5-bromofurfuryl)-1-piperidyl-4-amine"23917377
C531033N-(1-(2,3-dimethoxyphenyl)-4-methyl-3-penten-1-yl)-1-(5-bromofurfuryl)-1-piperidyl-4-amine"N-(1-(2,3-dimethoxyphenyl)-4-methyl-3-penten-1-yl)-1-(5-bromofurfuryl)-1-piperidyl-4-amine results in decreased activity of KCNH2 protein"23917377
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in decreased expression of KCNH2 protein]22853924
C029178naftifinenaftifine results in decreased activity of KCNH2 protein28551711
C005273naringeninAmiodarone promotes the reaction [naringenin results in decreased activity of KCNH2 protein]18057881
C005273naringeninazimilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]18057881
C005273naringenindofetilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]18057881
C005273naringeninnaringenin promotes the reaction [Amiodarone results in decreased activity of KCNH2 protein]18057881
C005273naringeninnaringenin promotes the reaction [azimilide results in decreased activity of KCNH2 protein]18057881
C005273naringeninnaringenin promotes the reaction [dofetilide results in decreased activity of KCNH2 protein]18057881
C005273naringeninnaringenin promotes the reaction [Quinidine results in decreased activity of KCNH2 protein]18057881
C005273naringeninnaringenin results in decreased activity of KCNH2 protein18057881
C005273naringeninQuinidine promotes the reaction [naringenin results in decreased activity of KCNH2 protein]18057881
C051752nefazodonenefazodone affects the activity of KCNH2 protein26821276
C051752nefazodonenefazodone binds to and results in decreased activity of KCNH2 protein24374264|2682127
C051752nefazodonenefazodone results in decreased activity of KCNH2 protein24052561|2855171
D009538NicotineNicotine results in increased expression of KCNH2 mRNA17997037
C076259nifekalantnifekalant affects the activity of KCNH2 protein22020101
C076259nifekalantnifekalant results in decreased activity of KCNH2 protein28551711
D009544Niflumic AcidE 4031 inhibits the reaction [Niflumic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]]12359267
D009544Niflumic AcidNiflumic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]12359267
C054074niguldipineniguldipine results in decreased activity of KCNH2 protein28551711
C012655nimesulidenimesulide results in decreased activity of KCNH2 protein24052561
D009553NimodipineNimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium]11040061
D009610NitrovinNitrovin results in decreased activity of KCNH2 protein28551711
C041094N,N-bis(3,4-dimethoxyphenethyl)-N-methylamine"N,N-bis(3,4-dimethoxyphenethyl)-N-methylamine binds to and results in decreased activity of KCNH2 protein"14678746
C504726N-(n-butyl)-(bis-fluorophenyl)methoxytropaneN-(n-butyl)-(bis-fluorophenyl)methoxytropane inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D009628NonachlazineNonachlazine results in decreased activity of KCNH2 protein28551711
C036139norfluoxetineKCNH2 protein affects the susceptibility to norfluoxetine16967046
C036139norfluoxetinenorfluoxetine affects the localization of KCNH2 protein16967046
C036139norfluoxetinenorfluoxetine results in decreased activity of KCNH2 protein16967046
D009661NortriptylineNortriptyline inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C100288octoclothepineoctoclothepine results in decreased activity of KCNH2 protein28551711
D017830OctoxynolOctoxynol results in decreased activity of KCNH2 protein24052561
C076029olanzapineolanzapine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C076029olanzapineolanzapine results in decreased activity of KCNH2 protein16494862
C048335oligomycin Boligomycin B results in decreased activity of KCNH2 protein24052561
C016340o,p'-DDT"o,p'-DDT results in decreased activity of KCNH2 protein"21362439
C016340o,p'-DDT"[o,p'-DDT results in decreased activity of KCNH2 protein] which results in decreased import of Thallium"21362439
D009966OrphenadrineOrphenadrine binds to and results in decreased activity of KCNH2 protein14678746
C005461oxeladinoxeladin results in decreased activity of KCNH2 protein28551711
C022155oxiconazoleoxiconazole results in decreased activity of KCNH2 protein28551711
C037573oxymatrineoxymatrine inhibits the reaction [arsenic trioxide results in decreased localization of KCNH2 protein]23103450
C037573oxymatrineoxymatrine results in increased expression of KCNH2 protein23103450
C100201oxyphencyclimineoxyphencyclimine results in decreased activity of KCNH2 protein28551711
D000068882Paliperidone PalmitatePaliperidone Palmitate results in decreased activity of KCNH2 protein21394035
C083418palonosetronpalonosetron results in decreased activity of KCNH2 protein28551711
C004564panaxadiolpanaxadiol affects the activity of KCNH2 protein15842772
C004563panaxatriolpanaxatriol affects the activity of KCNH2 protein15842772
D010208PapaverinePapaverine results in decreased activity of KCNH2 protein17376289
D010419PentamidinePentamidine affects the localization of and affects the activity of KCNH2 protein15340016
D010419PentamidinePentamidine affects the localization of and results in decreased activity of KCNH2 protein15711590
D010419PentamidinePentamidine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D010419PentamidinePentamidine results in decreased activity of KCNH2 protein21158687
D010419PentamidinePentamidine results in decreased activity of KCNH2 protein19652455
C046012pentanalpentanal results in increased expression of KCNH2 mRNA26079696
D010424PentobarbitalPentobarbital results in decreased activity of KCNH2 protein11862331
D010480PerhexilinePerhexiline binds to KCNH2 protein18701618
C023470perhexiline maleateperhexiline maleate results in decreased activity of KCNH2 protein28551711
C084584periciazinepericiazine results in decreased activity of KCNH2 protein28551711
C065533perospironeperospirone results in decreased activity of KCNH2 protein28551711
D010546PerphenazinePerphenazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D010546PerphenazinePerphenazine results in decreased activity of KCNH2 protein28551711
C031637phenothiazinephenothiazine results in decreased activity of KCNH2 protein28551711
D010646PhentolaminePhentolamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D010646PhentolaminePhentolamine results in decreased activity of KCNH2 protein24052561
D010656PhenylephrinePhenylephrine affects the reaction [KCNH2 protein results in increased transport of Potassium]19419905
D010672PhenytoinPhenytoin results in decreased activity of KCNH2 protein21158687
C041648pimobendanpimobendan results in decreased activity of KCNH2 protein24052561
D010868PimozidePimozide binds to and results in decreased activity of KCNH2 protein14678746
D010868PimozidePimozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D010868PimozidePimozide results in decreased activity of KCNH2 protein15671647|2405256
C067601piperacetazinepiperacetazine results in decreased activity of KCNH2 protein28551711
C010293piperidolatepiperidolate results in decreased activity of KCNH2 protein28551711
D010918PizotylinePizotyline results in decreased activity of KCNH2 protein28551711
D011188Potassium[[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]19419905
D011188PotassiumE 4031 inhibits the reaction [Flufenamic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]]12359267
D011188PotassiumE 4031 inhibits the reaction [Niflumic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]]12359267
D011188PotassiumFlufenamic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]12359267
D011188PotassiumFluoxetine inhibits the reaction [KCNH2 protein results in increased transport of Potassium]11805215
D011188Potassium[iron(III)-ascorbic acid complex results in increased abundance of Reactive Oxygen Species] affects the reaction [KCNH2 protein affects the transport of Potassium]9326673
D011188Potassium[KCNH2 protein binds to KCNE2 protein] which results in increased transport of Potassium15679475
D011188Potassium[KCNH2 protein binds to KCNH2 protein] which results in increased transport of Potassium15679475
D011188PotassiumKCNH2 protein results in increased transport of Potassium11805215|1235926
D011188PotassiumNiflumic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]12359267
D011188PotassiumPhenylephrine affects the reaction [KCNH2 protein results in increased transport of Potassium]19419905
D011188PotassiumPotassium affects the reaction [dofetilide analog inhibits the reaction [dofetilide binds to KCNH2 protein]]24200993
D011188PotassiumPotassium affects the stability of and affects the localization of KCNH2 protein modified form19139152
D011188PotassiumPotassium deficiency affects the folding of KCNH2 protein19139152
D011188PotassiumPotassium inhibits the reaction [Amiodarone results in decreased activity of KCNH2 protein]15618689
D011188PotassiumPotassium inhibits the reaction [azimilide results in decreased activity of KCNH2 protein]16960444
D011188PotassiumPotassium inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein]16960444
D011188PotassiumPotassium inhibits the reaction [dronedarone results in decreased activity of KCNH2 protein]15618689
D011188PotassiumPotassium inhibits the reaction [Gramicidin results in decreased expression of KCNH2 protein modified form]19139152
D011188PotassiumPotassium inhibits the reaction [Quinidine results in decreased activity of KCNH2 protein]16960444
D011188PotassiumPotassium inhibits the reaction [Sotalol results in decreased activity of KCNH2 protein]16960444
D011188PotassiumPotassium promotes the reaction [Astemizole binds to KCNH2 protein]24200993
D011188PotassiumPotassium promotes the reaction [dofetilide binds to KCNH2 protein]24200993
D011299PrenylaminePrenylamine results in decreased activity of KCNH2 protein16278312
C053347prenylamine lactateprenylamine lactate results in decreased activity of KCNH2 protein28551711
C009185pridinolpridinol results in decreased activity of KCNH2 protein28551711
D011335ProadifenProadifen results in decreased activity of KCNH2 protein28551711
D011341ProbucolProbucol results in decreased activity of KCNH2 protein SNP15043509
D011342ProcainamideProcainamide binds to and results in decreased activity of KCNH2 protein15272206
C084820profenamineprofenamine results in decreased activity of KCNH2 protein28551711
D011370ProflavineProflavine results in decreased activity of KCNH2 protein28551711
D011374Progesterone2-Hydroxypropyl-beta-cyclodextrin inhibits the reaction [Progesterone results in decreased localization of KCNH2 protein]21525004
D011374ProgesteroneE 4031 inhibits the reaction [Progesterone results in decreased localization of KCNH2 protein]21525004
D011374ProgesteroneProgesterone results in decreased glycosylation of and results in decreased localization of and results in decreased activity of KCNH2 protein21525004
D011395PromazinePromazine results in decreased activity of KCNH2 protein28551711
D011405PropafenonePropafenone binds to and results in decreased activity of KCNH2 protein14678746
D011405PropafenonePropafenone affects the activity of KCNH2 protein16278312
D011405PropafenonePropafenone analog binds to and results in decreased activity of KCNH2 protein21175572
D011405PropafenonePropafenone binds to and results in decreased activity of KCNH2 protein21175572
D011405PropafenonePropafenone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D011405PropafenonePropafenone results in decreased activity of KCNH2 protein18724381|2405256
C005556propionaldehydepropionaldehyde results in increased expression of KCNH2 mRNA26079696
D011433PropranololPropranolol results in decreased activity of KCNH2 protein16314852
D011433PropranololPropranolol results in decreased activity of [KCNH2 protein binds to KCNE2 protein]15679475
D011433PropranololPropranolol results in decreased activity of [KCNH2 protein binds to KCNH2 protein]15679475
C009143proroxanproroxan results in decreased activity of KCNH2 protein28551711
C013294prosultiamineprosultiamine results in decreased activity of KCNH2 protein28551711
C017691pyrathiazinepyrathiazine results in decreased activity of KCNH2 protein28551711
C023666pyridinepyridine analog binds to KCNH2 protein17768047
D011738PyrilaminePyrilamine affects the activity of KCNH2 protein16278312
D011738PyrilaminePyrilamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C010423pyrithione zincpyrithione zinc results in decreased activity of KCNH2 protein28551711
D019289Pyruvic AcidPyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein]12531891
C024631pyrviniumpyrvinium results in decreased activity of KCNH2 protein28551711
D000069348Quetiapine FumarateQuetiapine Fumarate inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D000069348Quetiapine FumarateQuetiapine Fumarate results in decreased activity of KCNH2 protein28551711
C014742quifenadinequifenadine results in decreased activity of KCNH2 protein28551711
D011796QuinacrineQuinacrine results in decreased activity of KCNH2 protein28551711
D011802QuinidineAcids inhibits the reaction [Quinidine results in decreased activity of KCNH2 protein]15821840
D011802QuinidineKCNH2 gene mutant form results in decreased susceptibility to Quinidine15673388
D011802QuinidineKCNH2 gene SNP affects the susceptibility to Quinidine12695533
D011802Quinidinenaringenin promotes the reaction [Quinidine results in decreased activity of KCNH2 protein]18057881
D011802QuinidinePotassium inhibits the reaction [Quinidine results in decreased activity of KCNH2 protein]16960444
D011802QuinidineQuinidine affects the activity of KCNH2 protein22020101
D011802QuinidineQuinidine affects the localization of KCNH2 protein mutant form11741928
D011802QuinidineQuinidine binds to KCNH2 protein18701618
D011802QuinidineQuinidine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D011802QuinidineQuinidine promotes the reaction [naringenin results in decreased activity of KCNH2 protein]18057881
D011802QuinidineQuinidine results in decreased activity of KCNH2 protein11741928|1269553
D011802Quinidine[Quinidine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D011803QuinineKCNH2 gene SNP affects the susceptibility to Quinine12695533
D011803QuinineQuinine results in decreased activity of KCNH2 protein12695533|2855171
C060897ractopamineractopamine results in decreased activity of KCNH2 protein28551711
D000069458RanolazineRanolazine inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein]28521025
D000069458RanolazineRanolazine results in decreased activity of KCNH2 protein24052561
D017382Reactive Oxygen Species[iron(III)-ascorbic acid complex results in increased abundance of Reactive Oxygen Species] affects the reaction [KCNH2 protein affects the transport of Potassium]9326673
D017382Reactive Oxygen Species[iron(III)-ascorbic acid complex results in increased abundance of Reactive Oxygen Species] which affects the activity of KCNH2 protein9326673
C084826rescinnaminerescinnamine results in decreased activity of KCNH2 protein28551711
D012110ReserpineReserpine results in decreased activity of KCNH2 protein21362439|2855171
D012110Reserpine[Reserpine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
C059514resveratrolresveratrol inhibits the reaction [arsenic trioxide results in decreased activity of KCNH2 protein]25107562
C059514resveratrolresveratrol inhibits the reaction [arsenic trioxide results in decreased expression of KCNH2 protein]25107562
C034931rimcazolerimcazole results in decreased activity of KCNH2 protein28551711
D018967RisperidoneRisperidone results in decreased activity of KCNH2 protein14975710
D018967RisperidoneRisperidone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D016713RitanserinRitanserin inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D012370RobenidineRobenidine results in decreased activity of KCNH2 protein28551711
D012395Rose BengalRose Bengal results in decreased activity of KCNH2 protein28551711
D000068718Rosuvastatin CalciumRosuvastatin Calcium results in decreased activity of KCNH2 protein28551711
D012402RotenoneRotenone results in decreased activity of KCNH2 protein24052561
C047508rotigotinerotigotine results in decreased activity of KCNH2 protein28551711
C499186RPR260243RPR260243 results in increased activity of KCNH2 protein15976038
D012413RubidiumRubidium inhibits the reaction [Gramicidin results in decreased expression of KCNH2 protein modified form]19139152
D000068299Salmeterol XinafoateSalmeterol Xinafoate results in decreased activity of KCNH2 protein28551711
D012503SaponinsSaponins affects the activity of KCNH2 protein15842772
C116890SemaxinibSemaxinib results in decreased activity of KCNH2 protein28551711
C061131sertaconazolesertaconazole results in decreased activity of KCNH2 protein28551711
C066304sertindolesertindole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
C066304sertindolesertindole results in decreased activity of KCNH2 protein16278312|2405256
D020280SertralineSertraline results in decreased activity of KCNH2 protein28551711
C076731simendansimendan results in decreased activity of KCNH2 protein24052561
D019821SimvastatinSimvastatin results in decreased localization of KCNH2 protein21525004
C107044SM 21SM 21 promotes the reaction [ifenprodil results in decreased activity of KCNH2 protein]17460149
D012964SodiumSodium deficiency inhibits the reaction [Digoxin results in decreased expression of KCNH2 protein]19139152
C017947sodium arsenitesodium arsenite affects the methylation of KCNH2 gene28589171
D012966Sodium CyanideSodium Cyanide inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]12531891
C471405sorafenibsorafenib results in decreased activity of KCNH2 protein28551711
D013015SotalolKCNH2 gene mutant form results in decreased susceptibility to Sotalol15673388
D013015SotalolPotassium inhibits the reaction [Sotalol results in decreased activity of KCNH2 protein]16960444
D013015SotalolSotalol analog binds to KCNH2 protein18701618
D013015SotalolSotalol results in decreased activity of KCNH2 protein16757186|1696044
D013015SotalolSotalol results in decreased activity of KCNH2 protein22198052
D010042OuabainOuabain inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D010042OuabainOuabain results in decreased activity of KCNH2 protein21158687
D010042OuabainOuabain results in decreased expression of KCNH2 protein modified form19139152
D013331StrychnineStrychnine results in decreased activity of KCNH2 protein28551711
C473478sunitinibsunitinib results in decreased activity of KCNH2 protein21906609|2370760
C084824syrosingopinesyrosingopine results in decreased activity of KCNH2 protein28551711
D013619TacrineTacrine results in decreased activity of KCNH2 protein24052561
D013629TamoxifenTamoxifen binds to and results in decreased activity of KCNH2 protein15272206
D013629TamoxifenTamoxifen inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013629TamoxifenTamoxifen results in decreased activity of KCNH2 protein21362439|2855171
D013629Tamoxifen[Tamoxifen results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013629TamoxifenTamoxifen affects the expression of KCNH2 mRNA17555576
C086827tazarotenetazarotene results in decreased activity of KCNH2 protein28551711
C106448tecastemizoletecastemizole binds to and results in decreased activity of KCNH2 protein10376921
C000594735tenovin-1tenovin-1 results in decreased activity of KCNH2 protein28551711
C041359terbinafineterbinafine results in decreased activity of KCNH2 protein28551711
C037815terconazoleterconazole results in decreased activity of KCNH2 protein28551711
D016593TerfenadineTerfenadine binds to and results in decreased activity of KCNH2 protein12388285
D016593TerfenadineTerfenadine results in decreased activity of KCNH2 protein14975710
D016593TerfenadineTerfenadine binds to and results in decreased activity of KCNH2 protein14678746
D016593Terfenadine"2-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid inhibits the reaction [Terfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]]"21158687
D016593Terfenadinebeta-Cyclodextrins analog inhibits the reaction [Terfenadine results in decreased activity of KCNH2 protein]17513944
D016593TerfenadineChlorobutanol promotes the reaction [Terfenadine binds to and results in decreased activity of KCNH2 protein]20071423
D016593Terfenadineciclopirox inhibits the reaction [Terfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]]21158687
D016593TerfenadineHydrogen Peroxide inhibits the reaction [Terfenadine results in decreased activity of KCNH2 protein mutant form]10828461
D016593TerfenadineTerfenadine binds to and results in decreased activity of KCNH2 protein11005845|1170545
D016593TerfenadineTerfenadine binds to KCNH2 protein18701618|1926073
D016593Terfenadine[Terfenadine co-treated with dofetilide] binds to and results in decreased activity of KCNH2 protein20071423
D016593Terfenadine"[Terfenadine co-treated with ergotoxin, Centruroides noxius] binds to and results in decreased activity of KCNH2 protein"20071423
D016593Terfenadine[Terfenadine co-treated with Fluvoxamine] binds to and results in decreased activity of KCNH2 protein20071423
D016593TerfenadineTerfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D016593TerfenadineTerfenadine promotes the reaction [Chlorobutanol binds to and results in decreased activity of KCNH2 protein]20071423
D016593TerfenadineTerfenadine promotes the reaction [Ketoconazole results in decreased activity of KCNH2 protein]9694927
D016593TerfenadineTerfenadine results in decreased activity of KCNH2 protein10422790|1060495
D016593TerfenadineTerfenadine results in decreased activity of KCNH2 protein12052668
C010637terodilineterodiline inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of KCNH2 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of KCNH2 mRNA21592394
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of KCNH2 mRNA25172293
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of KCNH2 mRNA20055451
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KCNH2 mRNA17942748
C009424tetramethrintetramethrin results in decreased activity of KCNH2 protein28551711
C520892tetraoctylammonium bromidetetraoctylammonium bromide results in decreased activity of KCNH2 protein21362439|2331361
C520892tetraoctylammonium bromide[tetraoctylammonium bromide results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793Thallium"2-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid inhibits the reaction [Terfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]]"21158687
D013793Thallium"2-(4-(2-(3,4-dichlorophenyl)ethyl)phenylamino)benzoic acid promotes the reaction [KCNH2 protein results in increased transport of Thallium]"21158687
D013793Thallium"8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino(1,2-a)quinoxalin-5(6H)-one inhibits the reaction [KCNH2 protein results in increased transport of Thallium]"21158687
D013793ThalliumAmiodarone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793ThalliumAmitriptyline inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793Thalliumamperozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793ThalliumAripiprazole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumAstemizole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793Thallium[Benzethonium results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793ThalliumBepridil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumChlorpheniramine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumChlorpromazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793Thalliumciclopirox inhibits the reaction [Terfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]]21158687
D013793Thalliumciclopirox promotes the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumCisapride inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793ThalliumClomipramine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumClozapine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793Thallium[didecyldimethylammonium results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793Thallium[diphenylguanidine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793Thalliumdofetilide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793Thallium[domiphen results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793ThalliumDomperidone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793ThalliumDoxepin inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumDroperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumE 4031 inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793Thallium[Econazole results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793Thalliumeliprodil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793ThalliumFluoxetine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumFluvoxamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumHaloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793ThalliumImipramine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793ThalliumKCNH2 protein results in increased import of Thallium21158688
D013793ThalliumKCNH2 protein results in increased transport of Thallium21158687
D013793ThalliumKCNH2 results in increased transport of Thallium19583963
D013793ThalliumLidoflazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumLoratadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793Thallium[malachite green results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793ThalliumMaprotiline inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumMefloquine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumMethadyl Acetate inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumMibefradil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumN-(n-butyl)-(bis-fluorophenyl)methoxytropane inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793ThalliumNortriptyline inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793Thalliumolanzapine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793Thallium"[o,p'-DDT results in decreased activity of KCNH2 protein] which results in decreased import of Thallium"21362439
D013793ThalliumOuabain inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumPentamidine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumPerphenazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumPhentolamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793ThalliumPimozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793ThalliumPropafenone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumPyrilamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumQuetiapine Fumarate inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumQuinidine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793Thallium[Quinidine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793Thallium[Reserpine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793ThalliumRisperidone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumRitanserin inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793Thalliumsertindole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumTamoxifen inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793Thallium[Tamoxifen results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793ThalliumTerfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793Thalliumterodiline inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793Thallium[tetraoctylammonium bromide results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793ThalliumThioridazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumTrifluoperazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013793ThalliumTrifluperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793Thallium[Tritolyl Phosphates results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793Thalliumvanoxerine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793ThalliumVerapamil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D013793Thallium[Verapamil results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
D013793Thalliumvinpocetine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D013793ThalliumCisapride inhibits the reaction [KCNH2 protein results in increased transport of Thallium]20208034
D013793ThalliumHaloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]20208034
D013793ThalliumKCNH2 protein results in increased transport of Thallium20208034
C030950thiatonthiaton results in decreased activity of KCNH2 protein28551711
D013881ThioridazineThioridazine binds to and results in decreased activity of KCNH2 protein14678746
D013881ThioridazineThioridazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D013881ThioridazineThioridazine results in decreased activity of KCNH2 protein15671647|1627831
C009488thiphenamilthiphenamil results in decreased activity of KCNH2 protein28551711
C000609116thonzonium bromidethonzonium bromide results in decreased activity of KCNH2 protein28551711
C014224tiamulintiamulin results in decreased activity of KCNH2 protein28551711
C028458tipepidinetipepidine results in decreased activity of KCNH2 protein28551711
C066340tolcaponetolcapone results in decreased activity of KCNH2 protein24052561
C052342topiramatetopiramate results in decreased activity of KCNH2 protein15716081
D017312ToremifeneToremifene results in decreased activity of KCNH2 protein28551711
D014196TrazodoneTrazodone results in decreased activity of KCNH2 protein15740727|2855171
D014212TretinoinTretinoin results in decreased expression of KCNH2 mRNA15894607|2383079
C012589trichostatin Atrichostatin A results in decreased expression of KCNH2 mRNA24935251
C039276triclabendazoletriclabendazole results in decreased activity of KCNH2 protein28551711
C118602triethyl-(beta-4-stilbenoxyethyl)ammoniumtriethyl-(beta-4-stilbenoxyethyl)ammonium results in decreased activity of KCNH2 protein28551711
D014268TrifluoperazineTrifluoperazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]21158687
D014272TrifluperidolTrifluperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D014273TriflupromazineTriflupromazine results in decreased activity of KCNH2 protein28551711
C031242trimeprazine tartratetrimeprazine tartrate results in decreased activity of KCNH2 protein28551711
D014309TripelennamineTripelennamine results in decreased activity of KCNH2 protein28551711
D014311TriprolidineTriprolidine results in decreased activity of KCNH2 protein28551711
D014317Tritolyl PhosphatesTritolyl Phosphates results in decreased activity of KCNH2 protein21362439
D014317Tritolyl Phosphates[Tritolyl Phosphates results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
C030408tri-xylenyl phosphatetri-xylenyl phosphate results in decreased activity of KCNH2 protein21362439
C117845valnemulinvalnemulin results in decreased activity of KCNH2 protein28551711
D014635Valproic AcidValproic Acid affects the expression of KCNH2 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of KCNH2 mRNA23179753|2915479
D014635Valproic AcidValproic Acid results in increased methylation of KCNH2 gene29154799
C043425vanoxerinevanoxerine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
C060013vapiprostvapiprost results in decreased activity of KCNH2 protein28551711
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of KCNH2 gene25560391
D000069470Venlafaxine HydrochlorideVenlafaxine Hydrochloride results in decreased activity of KCNH2 protein21158687
D014700VerapamilVerapamil results in decreased activity of KCNH2 protein14975710
D014700VerapamilVerapamil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963|2115868
D014700VerapamilVerapamil results in decreased activity of KCNH2 protein15671647|2136243
D014700Verapamil[Verapamil results in decreased activity of KCNH2 protein] which results in decreased import of Thallium21362439
C041667vesnarinoneKCNH2 gene SNP affects the susceptibility to vesnarinone12695533
C041667vesnarinonevesnarinone results in decreased activity of KCNH2 protein12695533
D014749VincamineVincamine results in decreased activity of KCNH2 protein28551711
C013983vinpocetinevinpocetine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]19583963
D014810Vitamin EVitamin E inhibits the reaction [TNF protein results in decreased activity of KCNH2 protein]14973143
D014810Vitamin EVitamin E results in increased expression of KCNH2 mRNA19244175
C462299xaliprodenxaliproden results in decreased activity of KCNH2 protein28551711
D019820Xanthine[Xanthine co-treated with XDH protein] results in decreased activity of KCNH2 protein12531891|1497314
C043636zatebradinezatebradine results in decreased activity of KCNH2 protein28551711
D015031ZimeldineZimeldine results in decreased activity of KCNH2 protein24052561
C092292ziprasidoneziprasidone results in decreased activity of KCNH2 protein28551711

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000155phosphorelay sensor kinase activity-IEA-  
GO:0005242inward rectifier potassium channel activity-IDA7604285  8587608  
GO:0005242inward rectifier potassium channel activity-IMP14525949  
GO:0005249voltage-gated potassium channel activity-IBA21873635  
GO:0005249voltage-gated potassium channel activity-IDA11953308  21063088  28280240  
GO:0005251delayed rectifier potassium channel activity-IDA7736582  
GO:0005251delayed rectifier potassium channel activity-IGI25281747  
GO:0005515protein binding-IPI11953308  16361248  18923542  
GO:0031625ubiquitin protein ligase binding-IPI21463633  
GO:0042802identical protein binding-IPI8995352  24931372  
GO:0042803protein homodimerization activity-IPI8995352  
GO:0055131C3HC4-type RING finger domain binding-IPI25281747  
GO:0086008voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization-IC25281747  
GO:0097110scaffold protein binding-IPI18923542  
GO:1902282voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-IMP21536673  
GO ID GO Term Qualifier Evidence PubMed
GO:0000160phosphorelay signal transduction system-IEA-  
GO:0003064regulation of heart rate by hormone-TAS11953308  
GO:0023014signal transduction by protein phosphorylation-IEA-  
GO:0035690cellular response to drug-IDA7604285  
GO:0042391regulation of membrane potential-IBA21873635  
GO:0042391regulation of membrane potential-IDA8587608  21463633  
GO:0055075potassium ion homeostasis-IDA7604285  8587608  
GO:0060048cardiac muscle contraction-IMP21536673  
GO:0060306regulation of membrane repolarization-IDA7736582  21463633  
GO:0060307regulation of ventricular cardiac muscle cell membrane repolarization-IMP21536673  
GO:0071435potassium ion export-IDA7604285  
GO:0071805potassium ion transmembrane transport-IBA21873635  
GO:0071805potassium ion transmembrane transport-IDA7604285  7736582  8587608  11953308  21063088  
GO:0086005ventricular cardiac muscle cell action potential-IMP21536673  
GO:0086009membrane repolarization-IMP14525949  
GO:0086010membrane depolarization during action potential-IDA7604285  
GO:0086011membrane repolarization during action potential-IDA7736582  11953308  21463633  
GO:0086013membrane repolarization during cardiac muscle cell action potential-IMP21536673  
GO:0086091regulation of heart rate by cardiac conduction-IMP7889573  21536673  
GO:0097623potassium ion export across plasma membrane-IGI25281747  
GO:0098915membrane repolarization during ventricular cardiac muscle cell action potential-IMP21536673  
GO:1901379regulation of potassium ion transmembrane transport-IDA11953308  
GO:1901380negative regulation of potassium ion transmembrane transport-IDA7604285  8587608  
GO:1901381positive regulation of potassium ion transmembrane transport-IDA7736582  
GO:1902303negative regulation of potassium ion export-IDA7604285  8587608  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-IDA21463633  
GO:0005886plasma membrane-IMP25281747  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-IBA21873635  
GO:0008076voltage-gated potassium channel complex-IDA7604285  7736582  8587608  
GO:0008076voltage-gated potassium channel complex-IMP25281747  
GO:0009986cell surface-IDA21536673  
GO:0048471perinuclear region of cytoplasm-IMP25281747  
GO:1902937inward rectifier potassium channel complex-IMP14525949  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-112316Neuronal SystemTAS
R-HSA-1296071Potassium ChannelsTAS
R-HSA-1296072Voltage gated Potassium channelsTAS
R-HSA-397014Muscle contractionTAS
R-HSA-5576890Phase 3 - rapid repolarisationTAS
R-HSA-5576891Cardiac conductionTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18785031Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study. (2009)Raitakari OTAnn Med
19490382Genetic polymorphism of KCNH2 confers predisposition of acquired atrial fibrillation in Chinese. (2009 Oct)Wang QSJ Cardiovasc Electrophysiol