Gene: ENHO

375704
C9orf165|UNQ470
energy homeostasis associated
protein-coding
9p13.3
Ensembl:ENSG00000168913 Vega:OTTHUMG00000159589 UniprotKB:Q6UWT2
NC_000009.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.033e-1 (AD)  7.349e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SNTA10.9
C1orf610.884
METRN0.882
VEGFB0.877
NDRG20.87
CST30.856
AIFM30.852
IL17D0.845
MT30.841
SLC25A180.833

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.602
OR4F5-0.594
PLA2G4A-0.378
EMB-0.376
TXK-0.371
IGSF10-0.371
PTGS2-0.37
EFCAB13-0.353
SLCO4C1-0.344
FGF10-0.344

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of ENHO mRNA"28903501
C02017516 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione"16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in decreased expression of ENHO mRNA"20519331
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of ENHO mRNA]"19467301
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENHO mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENHO mRNA"27188386
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of ENHO mRNA27153756
D000447AldehydesAldehydes results in increased expression of ENHO mRNA25014914
D000638AmiodaroneAmiodarone results in decreased expression of ENHO mRNA24535564
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in decreased expression of ENHO mRNA26377693
C018475butyraldehydebutyraldehyde results in increased expression of ENHO mRNA26079696
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of ENHO mRNA27339419
D002994ClofibrateClofibrate results in decreased expression of ENHO mRNA23811191
D003042CocaineCocaine results in decreased expression of ENHO mRNA16710320
C093628cyproconazolecyproconazole results in decreased expression of ENHO mRNA22334560
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of ENHO mRNA28962523
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of ENHO mRNA]"19467301
D004041Dietary FatsDietary Fats results in increased expression of ENHO mRNA19467301
C109476epoxiconazoleepoxiconazole results in decreased expression of ENHO mRNA22334560
D003932HeroinHeroin results in decreased expression of ENHO mRNA16710320
D017313FenretinideFenretinide results in decreased expression of ENHO mRNA28973697
D017313FenretinideFenretinide results in increased expression of ENHO mRNA28973697
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of ENHO mRNA26752646
D007854LeadLead affects the expression of ENHO mRNA28903495
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of ENHO mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of ENHO mRNA"25554681|2562005
C046012pentanalpentanal results in increased expression of ENHO mRNA26079696
D010634PhenobarbitalPhenobarbital results in decreased expression of ENHO mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENHO mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of ENHO mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of ENHO mRNA23811191
C006253pirinixic acidpirinixic acid results in increased expression of ENHO mRNA20813756
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of ENHO mRNA28903501
C045950propiconazolepropiconazole results in decreased expression of ENHO mRNA21278054|2233456
C005556propionaldehydepropionaldehyde results in increased expression of ENHO mRNA26079696
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ENHO mRNA26377647
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of ENHO mRNA16214954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ENHO mRNA26290441
C032910triadimefontriadimefon results in decreased expression of ENHO mRNA23970803
C057693troglitazonetroglitazone results in decreased expression of ENHO mRNA28973697
D014635Valproic AcidValproic Acid affects the expression of ENHO mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of ENHO mRNA23179753|2718838
D014635Valproic AcidValproic Acid affects the expression of ENHO mRNA17963808
D014635Valproic AcidValproic Acid results in decreased expression of ENHO mRNA24535564
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of ENHO gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0045747positive regulation of Notch signaling pathway-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IEA-  
GO:0005886plasma membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27449397Involvement of adropin and adropin-associated genes in metabolic abnormalities of hemodialysis patients. (2016 Sep 1)Grzegorzewska AELife Sci