Gene: ACAT1

38
ACAT|MAT|T2|THIL
acetyl-CoA acetyltransferase 1
protein-coding
11q22.3
Ensembl:ENSG00000075239 MIM:607809 Vega:OTTHUMG00000166381 UniprotKB:P24752
NG_009888.1
PubMed
0   ANCO-SNPs
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.145e-2 (AD)  1.917e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GABARAPL20.915
NDUFB50.912
LDHB0.904
TSPAN30.902
ATPAF10.9
GLO10.897
PPT10.896
FH0.895
CETN20.893
HIGD1A0.893

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.773
OR4F29-0.748
MTRNR2L6-0.298
C8orf74-0.268
MTRNR2L9-0.261
MTRNR2L10-0.248
KRTAP4-8-0.244
MTRNR2L3-0.238
RAX2-0.238
FOLR3-0.237

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5768821-(2-trifluoromethoxyphenyl)-2-nitroethanone1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in increased expression of ACAT1 protein22527513
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of ACAT1 mRNA"28903501
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of ACAT1 mRNA"21346803
C0179063-dinitrobenzene3-dinitrobenzene results in increased oxidation of ACAT1 protein25716674
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of ACAT1 mRNA"25380136
C0030017-ketocholesterol[7-ketocholesterol co-treated with KNG1 protein modified form] results in decreased expression of ACAT1 mRNA23454145
C0030017-ketocholesterol[7-ketocholesterol co-treated with Rotenone] results in decreased expression of ACAT1 mRNA23454145
D000082AcetaminophenAcetaminophen results in decreased expression of ACAT1 mRNA25704631|2906747
D000082AcetaminophenAcetaminophen affects the expression of ACAT1 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of ACAT1 protein11752693
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of ACAT1 mRNA19770486
C412373AG 1879AG 1879 inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
D000517alpha-Chlorohydrinalpha-Chlorohydrin analog results in increased expression of ACAT1 protein26597043
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [iron(II)-ascorbic acid complex results in decreased activity of ACAT1 protein]10656290
D000638AmiodaroneAmiodarone results in increased expression of ACAT1 mRNA24489787
D000643Ammonium ChlorideAmmonium Chloride affects the expression of ACAT1 mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of ACAT1 mRNA24449571
C006632arsenic trioxidearsenic trioxide results in increased expression of ACAT1 mRNA22521957
D001280AtrazineAtrazine results in decreased expression of ACAT1 mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ACAT1 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ACAT1 mRNA22228805
D004958Estradiol[bisphenol A co-treated with Estradiol] results in decreased expression of ACAT1 mRNA26496021
C095105bexarotenebexarotene results in increased expression of ACAT1 mRNA16648578|1763041
C095105bexarotene[Tamoxifen co-treated with bexarotene] results in increased expression of ACAT1 mRNA17630414
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ACAT1 mRNA28628672
C006780bisphenol Abisphenol A affects the expression of ACAT1 mRNA21786754
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in decreased expression of ACAT1 mRNA26496021
C006780bisphenol Abisphenol A results in decreased expression of ACAT1 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ACAT1 mRNA28628672
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ACAT1 protein24527689
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in decreased expression of ACAT1 mRNA27174168
D002791Cholesterol, Dietary"[Cholesterol, Dietary co-treated with naringenin] affects the activity of ACAT1 protein"11396955
D002791Cholesterol, Dietary"[Cholesterol, Dietary co-treated with naringin] affects the activity of ACAT1 protein"11396955
D002994ClofibrateClofibrate results in increased expression of ACAT1 mRNA16081524
D002994ClofibrateClofibrate results in increased expression of ACAT1 mRNA23811191
D002994ClofibrateClofibrate results in increased expression of ACAT1 protein16470657
D003300CopperCopper results in decreased expression of ACAT1 mRNA22465980
D019327Copper SulfateCopper Sulfate results in decreased expression of ACAT1 mRNA19549813
D016572CyclosporineCyclosporine results in decreased expression of ACAT1 mRNA20106945|2383089
D016572CyclosporineCyclosporine results in decreased expression of ACAT1 mRNA19770486|2383089
C093628cyproconazolecyproconazole results in decreased expression of ACAT1 mRNA22334560
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of ACAT1 mRNA]27941970
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ACAT1 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ACAT1 mRNA28628672
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of ACAT1 mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of ACAT1 mRNA21266533
D002945CisplatinCisplatin results in increased expression of ACAT1 mRNA27392435
C000944dicrotophosdicrotophos results in decreased expression of ACAT1 mRNA28302478
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of ACAT1 mRNA26924002
D004041Dietary FatsDietary Fats results in increased expression of ACAT1 mRNA18042831
D004052Diethylnitrosamine[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACAT1 mRNA18253720
D004128DimethylnitrosamineDimethylnitrosamine results in decreased expression of ACAT1 mRNA25380136
C024629dimethyl phthalatedimethyl phthalate affects the expression of ACAT1 mRNA26924002
D004391DustDust results in decreased expression of ACAT1 mRNA17805423
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ACAT1 protein23301498
C109476epoxiconazoleepoxiconazole results in decreased expression of ACAT1 mRNA22334560
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of ACAT1 mRNA20227414
C002994ethylene dimethanesulfonateethylene dimethanesulfonate results in decreased expression of ACAT1 mRNA22711419
D005228Fatty Acids, Essential"Fatty Acids, Essential deficiency results in increased expression of ACAT1 mRNA"23333450
D005228Fatty Acids, Essential"NR1H2 gene mutant form inhibits the reaction [Fatty Acids, Essential deficiency results in decreased expression of ACAT1 mRNA]"23333450
D005228Fatty Acids, Essential"NR1H3 gene mutant form inhibits the reaction [Fatty Acids, Essential deficiency results in decreased expression of ACAT1 mRNA]"23333450
D011345Fenofibrate[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACAT1 mRNA18253720
D018120FinasterideFinasteride results in increased expression of ACAT1 mRNA24136188
C039281furanfuran binds to ACAT1 protein22240984
D005839GentamicinsGentamicins results in increased expression of ACAT1 mRNA22061828
C023427guanosine 5'-O-(2-thiodiphosphate)guanosine 5'-O-(2-thiodiphosphate) inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
D012701Serotonin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
D012701SerotoninAG 1879 inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
D012701Serotoninguanosine 5'-O-(2-thiodiphosphate) inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
D012701Serotoninrottlerin inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
D012701Serotoninsarpogrelate inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
D012701Serotoninsarpogrelate metabolite inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
D012701SerotoninSerotonin results in increased expression of ACAT1 mRNA alternative form16157345
D012701SerotoninSerotonin results in increased expression of and results in increased activity of ACAT1 protein16157345
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ACAT1 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ACAT1 mRNA28628672
D007213IndomethacinIndomethacin results in increased expression of ACAT1 mRNA28201806
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ACAT1 mRNA25613284
C051890irinotecanACAT1 protein results in increased susceptibility to irinotecan16734730
C051140iron(II)-ascorbic acid complexalpha-Tocopherol inhibits the reaction [iron(II)-ascorbic acid complex results in decreased activity of ACAT1 protein]10656290
C051140iron(II)-ascorbic acid complexiron(II)-ascorbic acid complex results in decreased activity of ACAT1 protein10656290
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ACAT1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ACAT1 mRNA28628672
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of ACAT1 mRNA15618438
C008261lead acetatelead acetate results in decreased expression of ACAT1 mRNA21829687
C045463leflunomideleflunomide results in increased expression of ACAT1 mRNA24136188
C052901lemongrass oillemongrass oil affects the expression of ACAT1 mRNA25976427
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of ACAT1 mRNA"24972896
C005219methyl cellosolvemethyl cellosolve results in increased expression of ACAT1 mRNA21427058
D008748MethylcholanthreneMethylcholanthrene results in decreased expression of ACAT1 mRNA18804290
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of ACAT1 protein26558463
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of ACAT1 protein26558463
C517284monomethyl phthalatemonomethyl phthalate affects the expression of ACAT1 mRNA26924002
D009020MorphineMorphine deficiency affects the reaction [Morphine results in decreased expression of ACAT1 protein]23056601
D009020MorphineMorphine results in decreased expression of ACAT1 protein23056601
C500085muraglitazarmuraglitazar results in increased expression of ACAT1 mRNA21515302
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of ACAT1 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of ACAT1 mRNA"25620056
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of ACAT1 mRNA25380136
C005273naringenin"[Cholesterol, Dietary co-treated with naringenin] affects the activity of ACAT1 protein"11396955
C005274naringin"[Cholesterol, Dietary co-treated with naringin] affects the activity of ACAT1 protein"11396955
D005996NitroglycerinNitroglycerin results in increased expression of ACAT1 mRNA12102619
D009840Oligomycins[Stigmasterol co-treated with Oligomycins] results in decreased expression of ACAT1 mRNA23454145
D000073878Palm OilPalm Oil results in increased expression of ACAT1 mRNA18042831
D010406PenicillinsPenicillins results in increased expression of ACAT1 mRNA23266720
D010416PentachlorophenolPentachlorophenol results in increased expression of ACAT1 mRNA24642059
C471071perfluorohexanesulfonic acidperfluorohexanesulfonic acid results in increased expression of ACAT1 mRNA21705711
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of ACAT1 mRNA23602845
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of ACAT1 protein26178269
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of ACAT1 mRNA20936131|2170571
C076994perfluorooctane sulfonic acidPPARA protein promotes the reaction [perfluorooctane sulfonic acid results in increased expression of ACAT1 mRNA]20936131
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of ACAT1 mRNA18692542|1916217
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of ACAT1 protein26879310
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of ACAT1 mRNA18804290
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of ACAT1 mRNA16221955|1916217
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of ACAT1 mRNA17097637
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ACAT1 mRNA]19482888
D010634PhenobarbitalPhenobarbital affects the expression of ACAT1 mRNA23091169
D010634PhenobarbitalPhenobarbital results in decreased expression of ACAT1 mRNA19482888
D010634PhenobarbitalPhenobarbital results in increased expression of ACAT1 mRNA19162173
D010695PhlorhizinPhlorhizin results in decreased expression of ACAT1 mRNA22538082
D010713PhosphatidylcholinesPhosphatidylcholines results in decreased activity of ACAT1 protein12559476
C060836pioglitazonepioglitazone results in decreased expression of ACAT1 mRNA15381068
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ACAT1 mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of ACAT1 mRNA18301758|2081375
C006253pirinixic acidpirinixic acid results in increased expression of ACAT1 protein15226431
C006253pirinixic acidpirinixic acid results in increased expression of ACAT1 mRNA16940010|1716443
D011192Potassium DichromatePotassium Dichromate results in increased expression of ACAT1 mRNA18332044
D017035PravastatinPravastatin results in decreased expression of ACAT1 mRNA27225895
D017035PravastatinPravastatin results in decreased expression of ACAT1 mRNA27225895
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of ACAT1 mRNA19162173
D011341ProbucolProbucol results in decreased activity of ACAT1 protein16292755
C045950propiconazolepropiconazole results in decreased expression of ACAT1 mRNA21278054|2233456
C010313pseudocumenepseudocumene results in decreased expression of ACAT1 protein17337753
D011794QuercetinQuercetin results in decreased expression of ACAT1 mRNA21632981
C059514resveratrolresveratrol inhibits the reaction [GBA protein mutant form results in decreased expression of ACAT1 protein]26027833
C089730rosiglitazonerosiglitazone results in decreased expression of ACAT1 mRNA15381068
C089730rosiglitazonerosiglitazone affects the expression of ACAT1 mRNA22013433
C089730rosiglitazonerosiglitazone results in increased expression of ACAT1 mRNA21515302
D012402Rotenone[7-ketocholesterol co-treated with Rotenone] results in decreased expression of ACAT1 mRNA23454145
D012402Rotenone[Stigmasterol co-treated with Rotenone] results in decreased expression of ACAT1 mRNA23454145
C085746rottlerinrottlerin inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
C064294sarpogrelatesarpogrelate inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
C064294sarpogrelatesarpogrelate metabolite inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]16157345
C080703SK&F 83959SK&F 83959 results in increased expression of ACAT1 protein25852303
C009277sodium arsenatesodium arsenate results in decreased expression of ACAT1 mRNA23922661
D013024Soybean OilSoybean Oil results in decreased activity of ACAT1 protein12559476
C075117squalestatin 1squalestatin 1 results in decreased expression of ACAT1 mRNA27225895
C075117squalestatin 1squalestatin 1 results in increased expression of ACAT1 mRNA27225895
D013265Stigmasterol[Stigmasterol co-treated with KNG1 protein modified form] results in decreased expression of ACAT1 mRNA23454145
D013265Stigmasterol[Stigmasterol co-treated with Oligomycins] results in decreased expression of ACAT1 mRNA23454145
D013265Stigmasterol[Stigmasterol co-treated with Rotenone] results in decreased expression of ACAT1 mRNA23454145
D013311StreptozocinStreptozocin results in decreased expression of ACAT1 protein19634143
D013311StreptozocinTrientine inhibits the reaction [Streptozocin results in decreased expression of ACAT1 protein]19634143
D013629Tamoxifen[Tamoxifen co-treated with bexarotene] results in increased expression of ACAT1 mRNA17630414
D013629TamoxifenTamoxifen results in decreased expression of ACAT1 mRNA17630414
D013629TamoxifenTamoxifen results in increased expression of ACAT1 mRNA17630414
C501413tesaglitazartesaglitazar results in increased expression of ACAT1 mRNA21515302
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ACAT1 mRNA24680724
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ACAT1 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ACAT1 mRNA21215274
D013752TetracyclineTetracycline results in decreased expression of ACAT1 mRNA24489787
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ACAT1 mRNA25613284
C475227thieno(2,3-c)isoquinolin-5-one"thieno(2,3-c)isoquinolin-5-one results in decreased expression of ACAT1 mRNA"19124646
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of ACAT1 protein22609517
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of ACAT1 protein22595367|2448615
D014266TrientineTrientine inhibits the reaction [Streptozocin results in decreased expression of ACAT1 protein]19634143
C057693troglitazonetroglitazone results in increased expression of ACAT1 mRNA21515302
D014415TunicamycinTunicamycin results in decreased expression of ACAT1 mRNA22378314
D014520UrethaneUrethane results in decreased expression of ACAT1 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of ACAT1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of ACAT1 mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of ACAT1 mRNA23179753
D014635Valproic AcidValproic Acid results in increased expression of ACAT1 mRNA24489787
D014640VancomycinVancomycin results in increased expression of ACAT1 mRNA18930951
C029297vinylidene chloridevinylidene chloride results in decreased expression of ACAT1 mRNA26682919
D014810Vitamin EVitamin E results in decreased activity of ACAT1 protein16292755
D019820Xanthine[Xanthine co-treated with XDH protein] results in decreased expression of ACAT1 protein19464573

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003985acetyl-CoA C-acetyltransferase activity-EXP17371050  
GO:0003985acetyl-CoA C-acetyltransferase activity-IBA21873635  
GO:0003985acetyl-CoA C-acetyltransferase activity-IDA17371050  
GO:0003985acetyl-CoA C-acetyltransferase activity-IMP1979337  8103405  
GO:0003988acetyl-CoA C-acyltransferase activity-IBA21873635  
GO:0016830carbon-carbon lyase activity-IDA17371050  
GO:0016885ligase activity, forming carbon-carbon bonds-IDA17371050  
GO:0019899enzyme binding-IEA-  
GO:0042803protein homodimerization activity-IEA-  
GO:0046872metal ion binding-IEA-  
GO:0050662coenzyme binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001889liver development-IEA-  
GO:0006085acetyl-CoA biosynthetic process-IDA17371050  
GO:0006550isoleucine catabolic process-IMP1979337  8103405  
GO:0006550isoleucine catabolic process-TAS17371050  
GO:0006635fatty acid beta-oxidation-IBA21873635  
GO:0007420brain development-IEA-  
GO:0009083branched-chain amino acid catabolic process-TAS-  
GO:0009725response to hormone-IEA-  
GO:0014070response to organic cyclic compound-IEA-  
GO:0015936coenzyme A metabolic process-IDA17371050  
GO:0015937coenzyme A biosynthetic process-IDA17371050  
GO:0042594response to starvation-IEA-  
GO:0046356acetyl-CoA catabolic process-IDA17371050  
GO:0046951ketone body biosynthetic process-TAS-  
GO:0046952ketone body catabolic process-IMP1979337  
GO:0046952ketone body catabolic process-TAS-  
GO:0051260protein homooligomerization-IEA-  
GO:0060612adipose tissue development-IEA-  
GO:0072229metanephric proximal convoluted tubule development-IEA-  
GO:1902224ketone body metabolic process-IC17371050  
GO:1902860propionyl-CoA biosynthetic process-IDA17371050  
GO ID GO Term Qualifier Evidence PubMed
GO:0005739mitochondrion-IBA21873635  
GO:0005739mitochondrion-IDA-  
GO:0005759mitochondrial matrix-TAS-  
GO:0070062extracellular exosome-HDA19056867  23533145  
KEGG ID KEGG Term
hsa00071Fatty acid degradation
hsa00072Synthesis and degradation of ketone bodies
hsa00280Valine, leucine and isoleucine degradation
hsa00310Lysine degradation
hsa00380Tryptophan metabolism
hsa00620Pyruvate metabolism
hsa00630Glyoxylate and dicarboxylate metabolism
hsa00640Propanoate metabolism
hsa00650Butanoate metabolism
hsa00900Terpenoid backbone biosynthesis
hsa01100Metabolic pathways
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-556833Metabolism of lipidsTAS
R-HSA-70895Branched-chain amino acid catabolismTAS
R-HSA-71291Metabolism of amino acids and derivativesTAS
R-HSA-74182Ketone body metabolismTAS
R-HSA-77108Utilization of Ketone BodiesTAS
R-HSA-77111Synthesis of Ketone BodiesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28550509Possible involvement of ACSS2 gene in alcoholism. (2017 Sep)Ribeiro AFJ Neural Transm (Vienna)