| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| HAPLN1 | 0.885 |
| VIP | 0.877 |
| DLX1 | 0.875 |
| ZNF385D | 0.865 |
| VWC2 | 0.858 |
| IGF1 | 0.851 |
| PTHLH | 0.847 |
| GAD2 | 0.844 |
| TAC3 | 0.836 |
| BTBD11 | 0.834 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| TIMP1 | -0.577 |
| PLIN2 | -0.568 |
| AGTRAP | -0.564 |
| LOXL2 | -0.559 |
| CDA | -0.555 |
| CLEC4E | -0.55 |
| PLP2 | -0.548 |
| HEBP2 | -0.546 |
| ANG | -0.544 |
| SERPINA3 | -0.543 |
| ID | Drug Name | Drug Type | CAS Num | Status | Role |
|---|---|---|---|---|---|
| DB00398 | Sorafenib | Small Molecule | 284461-73-0 | Approved|Investigational | Target |
| DB00619 | Imatinib | Small Molecule | 152459-95-5 | Approved | Target |
| DB01254 | Dasatinib | Small Molecule | 302962-49-8 | Approved|Investigational | Target |
| DB01268 | Sunitinib | Small Molecule | 557795-19-4 | Approved|Investigational | Target |
| DB01962 | Phosphonotyrosine | Small Molecule | 21820-51-9 | Experimental | Target |
| DB04868 | Nilotinib | Small Molecule | 641571-10-0 | Approved|Investigational | Target |
| DB05146 | XL820 | Small Molecule | - | Investigational | Target |
| DB05913 | OSI-930 | Small Molecule | Investigational | Target | |
| DB06080 | ABT-869 | Small Molecule | - | Investigational | Target |
| DB06589 | Pazopanib | Small Molecule | 444731-52-6 | Approved | Target |
| DB06595 | Midostaurin | Small Molecule | 120685-11-2 | Approved|Investigational | Target |
| DB08896 | Regorafenib | Small Molecule | 755037-03-7 | Approved | Target |
| DB08901 | Ponatinib | Small Molecule | 943319-70-8 | Approved|Investigational | Target |
| DB09078 | Lenvatinib | Small Molecule | 417716-92-8 | Approved|Investigational | Target |
| DB09103 | Ancestim | BiotechDrug | 163545-26-4 | Approved|Investigational|Withdrawn | Target |
| DB12742 | Amuvatinib | Small Molecule | 850879-09-3 | Investigational | Target |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| C026486 | 1,2,5,6-dibenzanthracene | "1,2,5,6-dibenzanthracene results in decreased expression of KIT mRNA" | 26377693 |
| C105351 | 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of KIT protein" | 23284745 |
| C054919 | 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene | "[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA" | 19422813 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [KIT protein polymorphism results in increased expression of HMOX1 protein] | 17420286 |
| C011269 | 2,5-hexanedione | "2,5-hexanedione results in decreased expression of KIT protein" | 17725299 |
| C011269 | 2,5-hexanedione | "resveratrol inhibits the reaction [2,5-hexanedione results in decreased expression of KIT protein]" | 17725299 |
| C472791 | 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid | 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of KIT mRNA | 16788091 |
| C530773 | 3,5-diethoxycarbonyl-1,4-dihydrocollidine | "3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of KIT mRNA" | 27052460 |
| C530773 | 3,5-diethoxycarbonyl-1,4-dihydrocollidine | "SULT2B1 protein promotes the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of KIT mRNA]" | 27052460 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C549569 | 4-cyano-N-(2-(1-cyclohexen-1-yl)-4-(1-((dimethylamino)acetyl)-4-piperidinyl)phenyl)-1H-imidazole-2-carboxamide | 4-cyano-N-(2-(1-cyclohexen-1-yl)-4-(1-((dimethylamino)acetyl)-4-piperidinyl)phenyl)-1H-imidazole-2-carboxamide results in decreased activity of KIT protein | 22039836 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of KIT mRNA | 18467506 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of KIT protein | 18467506 |
| D019342 | Acetic Acid | Acetic Acid affects the expression of KIT protein | 21296659 |
| D000171 | Acrolein | Acrolein results in increased expression of KIT mRNA | 18515264 |
| D020106 | Acrylamide | Acrylamide results in increased expression of KIT mRNA | 22459607 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased methylation of KIT gene | 27153756 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased expression of KIT mRNA | 23630614 |
| D000452 | Aldrin | "[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA" | 19422813 |
| D000452 | Aldrin | [Lindane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA | 28263720 |
| D000487 | Allethrin | Allethrin results in decreased expression of KIT mRNA | 28181402 |
| C040534 | alpha-hexachlorocyclohexane | alpha-hexachlorocyclohexane results in increased expression of KIT mRNA | 16940010 |
| D000535 | Aluminum | [APP protein modified form binds to Aluminum] which results in increased expression of KIT mRNA | 21298039 |
| C077990 | alvocidib | alvocidib results in decreased expression of KIT mRNA | 16740725 |
| C077990 | alvocidib | alvocidib results in decreased expression of KIT promoter | 16740725 |
| C077990 | alvocidib | alvocidib results in decreased phosphorylation of KIT protein | 16740725 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of KIT mRNA | 16483693 |
| D001151 | Arsenic | Arsenic results in decreased expression of KIT mRNA | 19654921 |
| D001152 | Arsenicals | Arsenicals results in decreased expression of KIT mRNA | 28625800 |
| C006632 | arsenic trioxide | arsenic trioxide promotes the reaction [GLI3 protein binds to KIT promoter] | 27793025 |
| C006632 | arsenic trioxide | arsenic trioxide promotes the reaction [[GLI3 protein binds to KIT promoter] which results in decreased expression of KIT mRNA] | 27793025|2779302 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of KIT mRNA | 23815908|2779302 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of KIT protein modified form | 19619438 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased phosphorylation of KIT protein | 19950550 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of KIT mRNA | 26705709 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of KIT protein | 20609355 |
| C047721 | artemisic acid | artemisic acid results in decreased expression of KIT mRNA | 23063590 |
| D001285 | Atropine | Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] | 17390078 |
| C030935 | benz(a)anthracene | benz(a)anthracene results in increased expression of KIT mRNA | 26377693 |
| C006703 | benzo(b)fluoranthene | benzo(b)fluoranthene results in increased expression of KIT mRNA | 26377693 |
| D004958 | Estradiol | [Parathion co-treated with Estradiol] results in increased expression of KIT protein | 17622325 |
| D004958 | Estradiol | Estradiol affects the expression of KIT mRNA | 15598610 |
| D004958 | Estradiol | Estradiol results in increased expression of KIT mRNA | 19484750 |
| D004958 | Estradiol | KIT protein affects the reaction [KITLG protein inhibits the reaction [FSHB protein results in increased abundance of Estradiol]] | 22366471 |
| D004958 | Estradiol | KIT protein affects the reaction [FSHB protein results in increased abundance of Estradiol] | 22366471 |
| C472777 | bisperoxovanadium | bisperoxovanadium results in increased expression of KIT protein | 17601985 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of KIT mRNA | 24066056|2518105 |
| C006780 | bisphenol A | bisphenol A results in increased expression of KIT mRNA | 27208089 |
| C006780 | bisphenol A | bisphenol A results in increased methylation of KIT gene | 28505145 |
| D000069286 | Bortezomib | Bortezomib results in decreased expression of KIT mRNA | 20028860 |
| D000069286 | Bortezomib | Bortezomib results in decreased expression of KIT protein | 20028860 |
| C099813 | bromochloroacetic acid | bromochloroacetic acid results in decreased expression of KIT protein | 21296659 |
| D002066 | Busulfan | Busulfan results in decreased expression of KIT mRNA | 15388331 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of KIT mRNA | 24462979|2880113 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of KIT protein | 24462979|2880113 |
| C514968 | carboxymethyl-chitosan | [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of KIT protein] | 26612707 |
| C514968 | carboxymethyl-chitosan | [Curcumin binds to carboxymethyl-chitosan analog] which results in decreased expression of KIT protein | 26612707 |
| D002392 | Catechin | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of KIT mRNA | 24763279 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in decreased expression of KIT mRNA | 20350560 |
| C551994 | crizotinib | KIT gene mutant form results in decreased susceptibility to crizotinib | 22277784 |
| C461979 | CT52923 | CT52923 binds to and results in decreased activity of KIT protein | 15994924 |
| D003474 | Curcumin | [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of KIT protein] | 26612707 |
| D003474 | Curcumin | [Curcumin binds to carboxymethyl-chitosan analog] which results in decreased expression of KIT protein | 26612707 |
| C057862 | cyanoginosin LR | cyanoginosin LR results in increased expression of KIT | 24025782 |
| D000069439 | Dasatinib | Dasatinib binds to KIT protein | 18180381 |
| D000069439 | Dasatinib | Dasatinib results in decreased phosphorylation of KIT protein | 20145167 |
| D000069439 | Dasatinib | Dasatinib results in decreased activity of KIT protein | 21128601 |
| D003630 | Daunorubicin | Daunorubicin results in decreased expression of KIT mRNA | 27090888 |
| D003634 | DDT | [Lindane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA | 28263720 |
| D003907 | Dexamethasone | Dexamethasone results in decreased expression of KIT mRNA | 10335920 |
| D003907 | Dexamethasone | Dexamethasone results in decreased expression of KIT protein | 10335920 |
| C028009 | diallyl disulfide | diallyl disulfide results in increased expression of KIT protein | 23663050 |
| C042577 | diallyl trisulfide | diallyl trisulfide results in increased expression of KIT protein | 23663050 |
| D003976 | Diazinon | Diazinon results in increased methylation of KIT gene | 22964155 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of KIT mRNA | 21745491 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of KIT protein | 21745491|2428560 |
| D003993 | Dibutyl Phthalate | resveratrol inhibits the reaction [Dibutyl Phthalate results in decreased expression of KIT protein] | 24285609 |
| D002945 | Cisplatin | [Cisplatin co-treated with Paclitaxel] results in increased expression of KIT mRNA | 20705681 |
| D002945 | Cisplatin | [Cisplatin co-treated with Paclitaxel] results in increased expression of KIT protein | 20705681 |
| D002945 | Cisplatin | [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of KIT protein | 21342274 |
| D002945 | Cisplatin | Cisplatin results in increased expression of KIT protein | 21618587 |
| D003632 | Dichlorodiphenyldichloroethane | "[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA" | 19422813 |
| D003632 | Dichlorodiphenyldichloroethane | [Lindane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA | 28263720 |
| D003633 | Dichlorodiphenyl Dichloroethylene | "[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA" | 19422813 |
| D003633 | Dichlorodiphenyl Dichloroethylene | [Lindane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA | 28263720 |
| D004026 | Dieldrin | "[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA" | 19422813 |
| D004026 | Dieldrin | [Lindane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA | 28263720 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in increased expression of KIT mRNA | 24804967 |
| D004051 | Diethylhexyl Phthalate | [Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of KIT mRNA | 25031359 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of KIT protein | 25242112 |
| D002117 | Calcitriol | Calcitriol results in decreased expression of KIT mRNA | 8931875 |
| D002117 | Calcitriol | Calcitriol results in decreased expression of KIT protein | 8931875 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | "9,10-Dimethyl-1,2-benzanthracene results in decreased expression of KIT protein" | 24576726 |
| D004732 | Endrin | [Lindane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA | 28263720 |
| C118739 | entinostat | entinostat results in increased expression of KIT mRNA | 26272509 |
| C118739 | entinostat | "[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C045651 | epigallocatechin gallate | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIT mRNA | 22079256 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of KIT mRNA | 17942748 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in increased mutagenesis of KIT exon | 15731517 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in increased mutagenesis of KIT gene | 15820307 |
| D015025 | Zearalenone | Zearalenone results in decreased expression of KIT mRNA | 26386189 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene results in increased expression of KIT protein | 15133858 |
| D005472 | Fluorouracil | Fluorouracil results in decreased expression of KIT protein | 21296659 |
| D005472 | Fluorouracil | KIT protein mutant form affects the susceptibility to Fluorouracil | 19100679 |
| D005557 | Formaldehyde | Formaldehyde results in increased expression of KIT protein | 28373009 |
| C551027 | GANT 61 | GANT 61 results in decreased expression of KIT mRNA | 27793025 |
| D019833 | Genistein | Genistein results in decreased expression of KIT mRNA | 21048042 |
| D019833 | Genistein | [Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of KIT mRNA | 25031359 |
| D005839 | Gentamicins | Gentamicins results in decreased expression of KIT mRNA | 22061828 |
| C511402 | Grape Seed Proanthocyanidins | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of KIT mRNA | 24763279 |
| C511402 | Grape Seed Proanthocyanidins | Grape Seed Proanthocyanidins inhibits the reaction [Nickel results in increased expression of KIT protein] | 21417627 |
| D017313 | Fenretinide | Fenretinide results in increased expression of KIT mRNA | 28973697 |
| D000068877 | Imatinib Mesylate | Imatinib Mesylate inhibits the reaction [KIT protein results in increased expression of HMOX1 protein] | 17420286 |
| D000068877 | Imatinib Mesylate | Imatinib Mesylate results in increased expression of KIT mRNA | 27793025 |
| D000068877 | Imatinib Mesylate | Imatinib Mesylate results in decreased expression of KIT protein | 21295132 |
| D000068877 | Imatinib Mesylate | Imatinib Mesylate results in decreased activity of KIT protein | 16740725|1694079 |
| C519562 | imetelstat | imetelstat binds to and results in decreased activity of KIT protein | 21559248 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of KIT mRNA | 25613284 |
| D007501 | Iron | Iron deficiency results in decreased expression of KIT mRNA | 20368581 |
| C561695 | (+)-JQ1 compound | [PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of KIT mRNA | 25119042 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of KIT mRNA | 25982114 |
| D001556 | Lindane | [Lindane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA | 28263720 |
| D058185 | Magnetite Nanoparticles | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of KIT mRNA | 26378955 |
| D008344 | Maneb | Maneb results in decreased expression of KIT | 25803990 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of KIT mRNA | 28001369 |
| D018817 | N-Methyl-3,4-methylenedioxyamphetamine | "N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of KIT mRNA" | 26251327 |
| D008769 | Methylnitronitrosoguanidine | Methylnitronitrosoguanidine results in increased expression of KIT mRNA | 12634122 |
| C059539 | midostaurin | midostaurin inhibits the reaction [KIT protein polymorphism results in increased expression of HMOX1 protein] | 17420286 |
| C008548 | morin | morin inhibits the reaction [titanium dioxide results in decreased expression of KIT mRNA] | 28844848 |
| C568953 | N3-(4-(4-morpholinocyclohexyl)phenyl)-1-(pyridin-2-yl)-1H-1,2,4-triazole-3,5-diamine | "N3-(4-(4-morpholinocyclohexyl)phenyl)-1-(pyridin-2-yl)-1H-1,2,4-triazole-3,5-diamine results in decreased activity of KIT protein" | 21970471 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon analog results in decreased expression of KIT mRNA" | 25554681|2562005 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in decreased expression of KIT mRNA" | 25554681 |
| D009532 | Nickel | Grape Seed Proanthocyanidins inhibits the reaction [Nickel results in increased expression of KIT protein] | 21417627 |
| D009532 | Nickel | Nickel results in increased expression of KIT protein | 21417627 |
| C022838 | nickel chloride | nickel chloride affects the expression of KIT mRNA | 24670797 |
| C029938 | nickel sulfate | nickel sulfate results in decreased expression of KIT mRNA | 22714537 |
| C007350 | nitrofen | nitrofen results in increased expression of KIT mRNA | 26932254 |
| C007350 | nitrofen | nitrofen results in increased expression of KIT protein | 26932254 |
| C412603 | orantinib | orantinib results in decreased phosphorylation of and results in decreased activity of KIT protein | 16144927 |
| D010100 | Oxygen | Oxygen deficiency results in increased expression of KIT mRNA | 22711276 |
| D010100 | Oxygen | Valproic Acid inhibits the reaction [Oxygen deficiency results in increased expression of KIT mRNA] | 22711276 |
| D010100 | Oxygen | vorinostat inhibits the reaction [Oxygen deficiency results in increased expression of KIT mRNA] | 22711276 |
| D017239 | Paclitaxel | [Cisplatin co-treated with Paclitaxel] results in increased expression of KIT mRNA | 20705681 |
| D017239 | Paclitaxel | [Cisplatin co-treated with Paclitaxel] results in increased expression of KIT protein | 20705681 |
| C496932 | panobinostat | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C496932 | panobinostat | panobinostat results in increased expression of KIT mRNA | 26272509 |
| D010269 | Paraquat | Paraquat results in decreased expression of KIT protein | 20609355 |
| D010278 | Parathion | Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] | 17390078 |
| D010278 | Parathion | [Parathion co-treated with Estradiol] results in increased expression of KIT protein | 17622325 |
| D010278 | Parathion | Parathion results in increased expression of KIT protein | 17390078|1762232 |
| D052638 | Particulate Matter | Particulate Matter results in decreased expression of KIT mRNA | 23085030 |
| C516667 | pazopanib | pazopanib results in decreased activity of KIT protein | 19956806|2061637 |
| C506614 | PD 0325901 | [PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of KIT mRNA | 25119042 |
| C506614 | PD 0325901 | PD 0325901 results in decreased expression of KIT mRNA | 25119042 |
| D010654 | Phenylbutyrates | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of KIT protein" | 23284745 |
| D010705 | Phosgene | Phosgene affects the expression of KIT mRNA | 16300373 |
| C121565 | pifithrin | pifithrin results in decreased expression of KIT mRNA | 19098008 |
| C545373 | ponatinib | ponatinib results in decreased activity of KIT protein | 19878872 |
| C545373 | ponatinib | ponatinib results in decreased activity of KIT protein mutant form | 19878872 |
| C545373 | ponatinib | ponatinib results in decreased phosphorylation of KIT protein mutant form | 21482694 |
| C545373 | ponatinib | ponatinib affects the activity of KIT protein mutant form | 22301675 |
| C027373 | potassium chromate(VI) | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIT mRNA | 22079256 |
| C027373 | potassium chromate(VI) | potassium chromate(VI) results in decreased expression of KIT mRNA | 22079256 |
| C027373 | potassium chromate(VI) | potassium chromate(VI) results in increased expression of KIT mRNA | 22714537 |
| D011192 | Potassium Dichromate | Potassium Dichromate results in decreased expression of KIT protein | 26348139 |
| D011374 | Progesterone | Progesterone results in decreased expression of KIT mRNA | 23012394 |
| D011441 | Propylthiouracil | Propylthiouracil results in increased expression of KIT mRNA | 24780913 |
| C059514 | resveratrol | "resveratrol inhibits the reaction [2,5-hexanedione results in decreased expression of KIT protein]" | 17725299 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Dibutyl Phthalate results in decreased expression of KIT protein] | 24285609 |
| C116890 | Semaxinib | Semaxinib results in decreased activity of KIT protein | 12649163|1267371 |
| D012839 | Simazine | Simazine results in decreased expression of KIT mRNA | 25461544 |
| D019821 | Simvastatin | [Lindane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA | 28263720 |
| D020123 | Sirolimus | KIT protein mutant form promotes the reaction [Sirolimus results in decreased phosphorylation of EIF4EBP1 protein] | 16597595 |
| C009277 | sodium arsenate | sodium arsenate results in increased expression of KIT mRNA | 21795629 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of KIT mRNA | 12016162 |
| D053260 | Soot | Soot results in decreased expression of KIT mRNA | 26551751 |
| C471405 | sorafenib | sorafenib results in decreased phosphorylation of KIT protein | 19139124 |
| C471405 | sorafenib | sorafenib results in decreased activity of KIT protein | 20616376|2112860 |
| D004113 | Succimer | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of KIT mRNA | 26378955 |
| C473478 | sunitinib | sunitinib results in decreased activity of KIT protein | 20616376 |
| C112765 | tanespimycin | tanespimycin results in decreased expression of KIT protein | 16213582 |
| C112765 | tanespimycin | tanespimycin results in increased degradation of and results in decreased expression of KIT protein | 16061882 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of KIT mRNA | 26377647 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of KIT mRNA | 16102516|2104116 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of KIT mRNA | 25613284 |
| D019284 | Thapsigargin | Thapsigargin results in increased expression of KIT mRNA | 22378314 |
| C009495 | titanium dioxide | titanium dioxide affects the expression of KIT mRNA | 23557971 |
| C009495 | titanium dioxide | morin inhibits the reaction [titanium dioxide results in decreased expression of KIT mRNA] | 28844848 |
| C009495 | titanium dioxide | titanium dioxide results in decreased expression of KIT mRNA | 28844848 |
| D014118 | Toxins, Biological | "Toxins, Biological affects the expression of KIT mRNA" | 19682533 |
| D014212 | Tretinoin | "[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of KIT protein" | 23284745 |
| D014212 | Tretinoin | Tretinoin results in decreased activity of KIT protein | 21159206 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of KIT mRNA | 23724009 |
| D014212 | Tretinoin | Tretinoin results in increased expression of KIT mRNA | 21934132 |
| D014212 | Tretinoin | Tretinoin results in increased expression of KIT mRNA | 16788091 |
| D014212 | Tretinoin | Tretinoin results in increased expression of KIT mRNA | 17303670 |
| C012589 | trichostatin A | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C012589 | trichostatin A | trichostatin A results in increased expression of KIT mRNA | 24935251|2627250 |
| D014501 | Uranium | Uranium analog results in decreased expression of KIT mRNA | 27544493 |
| D014635 | Valproic Acid | Valproic Acid inhibits the reaction [Oxygen deficiency results in increased expression of KIT mRNA] | 22711276 |
| D014635 | Valproic Acid | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of KIT mRNA | 25979313 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of KIT mRNA | 19101580|2317975 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of KIT mRNA | 19136453 |
| D014638 | Vanadates | Vanadates results in increased expression of KIT mRNA | 22714537 |
| C025643 | vinclozolin | vinclozolin affects the expression of KIT mRNA | 19015723 |
| D014807 | Vitamin D | Vitamin D affects the expression of KIT mRNA | 20368581 |
| C111237 | vorinostat | vorinostat inhibits the reaction [Oxygen deficiency results in increased expression of KIT mRNA] | 22711276 |
| C111237 | vorinostat | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIT mRNA" | 27188386 |
| C111237 | vorinostat | vorinostat results in increased expression of KIT mRNA | 26272509 |
| C088658 | zoledronic acid | zoledronic acid results in increased expression of KIT mRNA | 24714768 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0002020 | protease binding | - | IEA | - |
| GO:0004709 | MAP kinase kinase kinase activity | - | IBA | 21873635 |
| GO:0004713 | protein tyrosine kinase activity | - | IBA | 21873635 |
| GO:0004713 | protein tyrosine kinase activity | - | TAS | 1717985 |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity | - | IBA | 21873635 |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity | - | IDA | 21640708 |
| GO:0004888 | transmembrane signaling receptor activity | - | IBA | 21873635 |
| GO:0005020 | stem cell factor receptor activity | - | IEA | - |
| GO:0005088 | Ras guanyl-nucleotide exchange factor activity | - | TAS | - |
| GO:0005515 | protein binding | - | IPI | 1382595 7523381 7537096 10377264 10397721 11018522 12878163 17662946 24728074 25241761 |
| GO:0005524 | ATP binding | - | IEA | - |
| GO:0019838 | growth factor binding | - | IBA | 21873635 |
| GO:0019955 | cytokine binding | - | IDA | 21640708 |
| GO:0031434 | mitogen-activated protein kinase kinase binding | - | IBA | 21873635 |
| GO:0042803 | protein homodimerization activity | - | IPI | 21640708 |
| GO:0046872 | metal ion binding | - | IEA | - |
| GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | - | TAS | - |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0000165 | MAPK cascade | - | TAS | - |
| GO:0000187 | activation of MAPK activity | - | IDA | 21640708 |
| GO:0001541 | ovarian follicle development | - | ISS | - |
| GO:0002318 | myeloid progenitor cell differentiation | - | IEA | - |
| GO:0002320 | lymphoid progenitor cell differentiation | - | IEA | - |
| GO:0002327 | immature B cell differentiation | - | ISS | - |
| GO:0002371 | dendritic cell cytokine production | - | ISS | - |
| GO:0002551 | mast cell chemotaxis | - | IDA | 20100931 |
| GO:0006357 | regulation of transcription by RNA polymerase II | - | TAS | - |
| GO:0006687 | glycosphingolipid metabolic process | - | IEA | - |
| GO:0006954 | inflammatory response | - | ISS | - |
| GO:0007165 | signal transduction | - | TAS | 9990072 |
| GO:0007275 | multicellular organism development | - | IBA | 21873635 |
| GO:0007283 | spermatogenesis | - | ISS | - |
| GO:0007283 | spermatogenesis | - | TAS | 16129412 |
| GO:0007286 | spermatid development | - | IEA | - |
| GO:0008284 | positive regulation of cell proliferation | - | IEA | - |
| GO:0008354 | germ cell migration | - | IEA | - |
| GO:0008360 | regulation of cell shape | - | ISS | - |
| GO:0008542 | visual learning | - | IEA | - |
| GO:0008584 | male gonad development | - | IEP | 17848411 |
| GO:0009968 | negative regulation of signal transduction | - | IBA | 21873635 |
| GO:0010628 | positive regulation of gene expression | - | IEA | - |
| GO:0010863 | positive regulation of phospholipase C activity | - | TAS | 16129412 |
| GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling | - | TAS | 16129412 |
| GO:0018108 | peptidyl-tyrosine phosphorylation | - | IDA | 21640708 |
| GO:0019221 | cytokine-mediated signaling pathway | - | IDA | 21640708 |
| GO:0019827 | stem cell population maintenance | - | TAS | 21057534 |
| GO:0030032 | lamellipodium assembly | - | ISS | - |
| GO:0030097 | hemopoiesis | - | TAS | 16129412 |
| GO:0030154 | cell differentiation | - | IBA | 21873635 |
| GO:0030217 | T cell differentiation | - | ISS | - |
| GO:0030218 | erythrocyte differentiation | - | ISS | - |
| GO:0030318 | melanocyte differentiation | - | ISS | - |
| GO:0030318 | melanocyte differentiation | - | TAS | 21057534 |
| GO:0030335 | positive regulation of cell migration | - | IEA | - |
| GO:0031274 | positive regulation of pseudopodium assembly | - | IEA | - |
| GO:0031532 | actin cytoskeleton reorganization | - | IDA | 1721869 |
| GO:0032762 | mast cell cytokine production | - | IDA | 20100931 |
| GO:0033674 | positive regulation of kinase activity | - | IBA | 21873635 |
| GO:0035019 | somatic stem cell population maintenance | - | IEA | - |
| GO:0035162 | embryonic hemopoiesis | - | ISS | - |
| GO:0035234 | ectopic germ cell programmed cell death | - | IEA | - |
| GO:0035701 | hematopoietic stem cell migration | - | IEA | - |
| GO:0035855 | megakaryocyte development | - | ISS | - |
| GO:0038093 | Fc receptor signaling pathway | - | IDA | 20100931 |
| GO:0038109 | Kit signaling pathway | - | IDA | 17662946 |
| GO:0038162 | erythropoietin-mediated signaling pathway | - | ISS | - |
| GO:0042127 | regulation of cell proliferation | - | TAS | 16129412 21057534 |
| GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein | - | IMP | 21135090 |
| GO:0043066 | negative regulation of apoptotic process | - | IBA | 21873635 |
| GO:0043069 | negative regulation of programmed cell death | - | IEA | - |
| GO:0043303 | mast cell degranulation | - | IMP | 20100931 |
| GO:0043410 | positive regulation of MAPK cascade | - | IBA | 21873635 |
| GO:0043410 | positive regulation of MAPK cascade | - | IMP | 21640708 |
| GO:0043473 | pigmentation | - | ISS | - |
| GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | - | TAS | 16129412 |
| GO:0043586 | tongue development | - | IEA | - |
| GO:0045747 | positive regulation of Notch signaling pathway | - | IEA | - |
| GO:0046427 | positive regulation of JAK-STAT cascade | - | IMP | 21135090 |
| GO:0046686 | response to cadmium ion | - | IEA | - |
| GO:0046777 | protein autophosphorylation | - | IDA | 21640708 |
| GO:0046854 | phosphatidylinositol phosphorylation | - | IEA | - |
| GO:0048070 | regulation of developmental pigmentation | - | IEA | - |
| GO:0048103 | somatic stem cell division | - | IEA | - |
| GO:0048170 | positive regulation of long-term neuronal synaptic plasticity | - | IEA | - |
| GO:0048565 | digestive tract development | - | ISS | - |
| GO:0048863 | stem cell differentiation | - | ISS | - |
| GO:0050673 | epithelial cell proliferation | - | IEA | - |
| GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound | - | ISS | - |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | - | IMP | 21135090 |
| GO:0051897 | positive regulation of protein kinase B signaling | - | TAS | - |
| GO:0060326 | cell chemotaxis | - | IDA | 1721869 |
| GO:0060374 | mast cell differentiation | - | ISS | - |
| GO:0060374 | mast cell differentiation | - | TAS | 16129412 |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | - | IBA | 21873635 |
| GO:0070662 | mast cell proliferation | - | TAS | 21057534 |
| GO:0097067 | cellular response to thyroid hormone stimulus | - | IEA | - |
| GO:0097324 | melanocyte migration | - | ISS | - |
| GO:0097326 | melanocyte adhesion | - | ISS | - |
| GO:0120072 | positive regulation of pyloric antrum smooth muscle contraction | - | IEA | - |
| GO:1904251 | regulation of bile acid metabolic process | - | IEA | - |
| GO:1904343 | positive regulation of colon smooth muscle contraction | - | IEA | - |
| GO:1904349 | positive regulation of small intestine smooth muscle contraction | - | IEA | - |
| GO:1905065 | positive regulation of vascular smooth muscle cell differentiation | - | IDA | 19088079 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0001669 | acrosomal vesicle | - | IEA | - |
| GO:0005615 | extracellular space | - | IDA | 14625290 |
| GO:0005737 | cytoplasm | - | IBA | 21873635 |
| GO:0005886 | plasma membrane | - | IDA | - |
| GO:0005886 | plasma membrane | - | TAS | - |
| GO:0005887 | integral component of plasma membrane | - | IBA | 21873635 |
| GO:0005911 | cell-cell junction | - | IEA | - |
| GO:0009897 | external side of plasma membrane | - | IEA | - |
| GO:0009898 | cytoplasmic side of plasma membrane | - | IEA | - |
| GO:0016021 | integral component of membrane | - | IEA | - |
| GO:0042629 | mast cell granule | - | IEA | - |
| GO:0043235 | receptor complex | - | IBA | 21873635 |
| KEGG ID | KEGG Term |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04144 | Endocytosis |
| hsa04640 | Hematopoietic cell lineage |
| hsa04916 | Melanogenesis |
| hsa05200 | Pathways in cancer |
| hsa05221 | Acute myeloid leukemia |
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-HSA-1257604 | PIP3 activates AKT signaling | TAS |
| R-HSA-1433557 | Signaling by SCF-KIT | TAS |
| R-HSA-1433557 | Signaling by SCF-KIT | IEA |
| R-HSA-1433559 | Regulation of KIT signaling | TAS |
| R-HSA-1433559 | Regulation of KIT signaling | IEA |
| R-HSA-162582 | Signal Transduction | TAS |
| R-HSA-162582 | Signal Transduction | IEA |
| R-HSA-1643685 | Disease | TAS |
| R-HSA-199418 | Negative regulation of the PI3K/AKT network | TAS |
| R-HSA-212436 | Generic Transcription Pathway | TAS |
| R-HSA-2219528 | PI3K/AKT Signaling in Cancer | TAS |
| R-HSA-2219530 | Constitutive Signaling by Aberrant PI3K in Cancer | TAS |
| R-HSA-5663202 | Diseases of signal transduction | TAS |
| R-HSA-5673001 | RAF/MAP kinase cascade | TAS |
| R-HSA-5683057 | MAPK family signaling cascades | TAS |
| R-HSA-5684996 | MAPK1/MAPK3 signaling | TAS |
| R-HSA-6811558 | PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | TAS |
| R-HSA-73857 | RNA Polymerase II Transcription | TAS |
| R-HSA-74160 | Gene expression (Transcription) | TAS |
| R-HSA-8864260 | Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | TAS |
| R-HSA-8866910 | TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | TAS |
| R-HSA-9006925 | Intracellular signaling by second messengers | TAS |
| R-HSA-9006934 | Signaling by Receptor Tyrosine Kinases | TAS |
| R-HSA-9006934 | Signaling by Receptor Tyrosine Kinases | IEA |
| PMID | Title (Year) | Author | Journal |
|---|---|---|---|
| 26268750 | [Relationship between histopathologic characteristics and epidermal growth factor receptor mutation in lung adenocarcinoma]. (2015 Mar) | Wang K | Zhonghua Bing Li Xue Za Zhi |
| 24067327 | Increase in brain-derived neurotrophic factor expression in early crack cocaine withdrawal. (2014 Jan) | von Diemen L | Int J Neuropsychopharmacol |
| 23887638 | Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors. (2013 Oct) | Chow WS | Arterioscler Thromb Vasc Biol |
| 27654735 | SNP rs3088308 is a risk factor for poor lung function in healthy smokers. (2016 Sep) | Shakoori TA | J Pak Med Assoc |
| 15898934 | Cigarette smoking and apoptosis. (2005 May) | Imirzalioglu P | J Periodontol |
| 16140223 | Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease. (2005 Oct) | Gessner C | Respir Med |
| 26667067 | Smoking and gingivitis: focus on inducible nitric oxide synthase, nitric oxide and basic fibroblast growth factor. (2016 Oct) | Ozdemir B | J Periodontal Res |
| 28712188 | A Novel Link Between Adipokines And Lipoprotein (A) To Contemplate Their Diagnostic Role In Patients With Stemi And Nstemi. (2017 Jan-Mar) | Rashid S | J Ayub Med Coll Abbottabad |
| 27646887 | [Expression of ALK protein in 7 371 pulmonary adenocarcinoma samples, with analysis of clinicopathologic features]. (2016 Sep 8) | Zhao RY | Zhonghua Bing Li Xue Za Zhi |
| 26943141 | Post-menopausal Women Exhibit Greater Interleukin-6 Responses to Mental Stress Than Older Men. (2016 Aug) | Endrighi R | Ann Behav Med |
| 15006985 | Tracheobronchial adenoid cystic carcinoma: a clinicopathologic study of 14 cases. (2004 Mar) | Albers E | Chest |
| 23319214 | Thymic carcinomas: clinicopathologic study of 37 cases from a single institution. (2013 Mar) | Thomas de Montpreville V | Virchows Arch |
| 28468035 | [Clinicopathologic characteristics of epidermal growth factor receptor mutations in non-small cell lung cancer in Xinjiang region]. (2017 May 8) | Shi Y | Zhonghua Bing Li Xue Za Zhi |
| 27784882 | Induction of Patient-Derived Xenograft Formation and Clinical Significance of Programmed Cell Death Ligand 1 (PD-L1) in Lung Cancer Patients. (2016 Oct 27) | Ma Y | Med Sci Monit |
| 23965952 | Somatic mutation of KIT is rare in small cell lung cancer patients from Northeast China. (2014 Feb) | Xuan H | Histol Histopathol |
| 20347921 | Protective effects of memantine and epicatechin on catechol-induced toxicity on Muller cells in vitro. (2010 May 27) | Mansoor S | Toxicology |
| 11289706 | Plasma endothelin-1 levels in liver cirrhosis. (2000) | Bruno CM | Int J Clin Lab Res |
| 27045722 | [Effects of artesunate on cigarette smoke-induced lung oxidative damage in mice and the expression of Nrf2 and the possible mechanism]. (2016 Mar 29) | Luo QZ | Zhonghua Yi Xue Za Zhi |
| 17142622 | Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk. (2006 Dec) | Humphries SE | J Med Genet |
| 25682300 | Serum interleukin-1beta in subjects with abdominal obesity and periodontitis. (2015 Sep-Oct) | Satpathy A | Obes Res Clin Pract |
| 29766003 | The Status of Nitric Oxide and its Backup, Heme Oxygenase 1, in Thromboangiitis Obliterans. (2018 Apr) | Aliee A | Rep Biochem Mol Biol |
| 28864204 | Soluble form of receptor for advanced glycation end products and incidence of new cardiovascular events among patients with cardiovascular disease. (2017 Nov) | Reichert S | Atherosclerosis |
| 29360590 | Genetic Variations of the COL4A1 Gene and Intracerebral Hemorrhage Risk: A Case-Control Study in a Chinese Han Population. (2018 Apr) | Lin S | World Neurosurg |
| 27784734 | Cardiovascular Risk Factors Associated With Blood Metabolite Concentrations and Their Alterations During a 4-Year Period in a Population-Based Cohort. (2016 Dec) | Lacruz ME | Circ Cardiovasc Genet |
| 17292720 | Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents. (2007 Mar) | Lee DC | Metabolism |
| 25421919 | The prevalence of EGFR mutations in non-small cell lung cancer in an unselected Caucasian population. (2015 Feb) | Skov BG | APMIS |
| 11387540 | Variations in treatment benefits influence smoking cessation: results of a randomised controlled trial. (2001 Jun) | Schauffler HH | Tob Control |
| 26948458 | Genetic systems for a new approach to risk of progression of diabetic retinopathy. (2016 May) | Pinazo-Duran MD | Arch Soc Esp Oftalmol |
| 24074435 | Polymorphisms of the cytokine genes TGFB1 and IL10 in a mixed-race population with Crohn's disease. (2013 Sep 27) | Almeida NP | BMC Res Notes |
| 23314596 | Serum surfactant protein D is associated with the prognosis in patients with chronic kidney disease. (2013 Jun) | Xie F | J Cardiovasc Med (Hagerstown) |
| 1571645 | Randomised trial of three approaches for marketing smoking cessation programmes to Australian general practitioners. (1992 Mar 14) | Cockburn J | BMJ |
| 24503791 | The evaluation of bcl-2 expression as a prognostic marker in early stage laryngeal cancer. (2013 Nov-Dec) | Gurlek U | Tumori |
| 29723116 | High inter-individual variability of serum xanthine oxidoreductase activity in IBD patients. (2018 May 3) | Meijer B | Nucleosides Nucleotides Nucleic Acids |
| 25627990 | Superoxide dismutase 2 as a marker to differentiate tuberculous pleural effusions from malignant pleural effusions. (2014) | Wang M | Clinics (Sao Paulo) |
| 29412334 | Gender differences of cannabis smoking on serum leptin levels: population-based study. (2018 Apr-June) | Moreira FP | Rev Bras Psiquiatr |
| 28145643 | Analysis of Fifty Hotspot Mutations of Lung Squamous Cell Carcinoma in Never-smokers. (2017 Mar) | Lee HY | J Korean Med Sci |
| 28056267 | [Association between eye absent homolog 4 gene polymorphisms and occupational noise-induced hearing loss]. (2017 Jan 6) | Yang QY | Zhonghua Yu Fang Yi Xue Za Zhi |
| 28056266 | [Association between variations in protocadherin 15 gene and occupational noise-induced hearing loss]. (2017 Jan 6) | Xu XR | Zhonghua Yu Fang Yi Xue Za Zhi |
| 16341695 | Immunohistochemical detection of apoptotic proteins, p53/Bax and JNK/FasL cascade, in the lung of rats exposed to cigarette smoke. (2006 Jun) | Wu CH | Arch Toxicol |
| 27479612 | Levels of Serum Brain-Derived Neurotrophic Factor in Schizophrenia. (2016 Aug) | Lee J | J Nerv Ment Dis |
| 25264883 | Associations between epidermal growth factor receptor gene mutation and serum tumor markers in advanced lung adenocarcinomas: a retrospective study. (2014 Sep) | Pan YQ | Chin Med Sci J |
| 16789978 | Plasma ghrelin concentrations are positively associated with carotid artery atherosclerosis in males. (2006 Jul) | Poykko SM | J Intern Med |
| 23075886 | Fine-needle aspiration cytology with c-kit immunocytochemical staining in the diagnosis of Warthin's tumor. (2012) | Kim JY | Acta Cytol |
| 23677728 | Factor XIII Val34Leu polymorphism in patients with cardiac syndrome X. (2014) | Guler GB | Cardiol J |
| 15970277 | Induction of apoptosis in the lung tissue from rats exposed to cigarette smoke involves p38/JNK MAPK pathway. (2005 Jun 30) | Kuo WH | Chem Biol Interact |
| 22221396 | Smoking influences salivary histamine levels in periodontal disease. (2012 May) | Bertl K | Oral Dis |
| 29744169 | Inflammatory mediator polymorphisms associate with initial periodontitis in adolescents. (2016 Dec) | Heikkinen AM | Clin Exp Dent Res |
| 26679059 | Cocaine abuse and effects in the serum levels of cytokines IL-6 and IL-10. (2016 Jan 1) | Moreira FP | Drug Alcohol Depend |
| 21483996 | Serum leptin level in the first trimester in ectopic versus normal pregnancies. (2011 Apr) | Kamyabi Z | Saudi Med J |
| 27998433 | [Effects of mTOR-Cdc42 signaling pathway on phagocytosis of alveolar macrophages in chronic obstructive pulmonary disease mice]. (2016 Dec 13) | Wang YJ | Zhonghua Yi Xue Za Zhi |
| 22513132 | Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study. (2012 Apr 18) | Chen Y | Arthritis Res Ther |
| 25425243 | Identification and characterisation of eight novel SERPINA1 Null mutations. (2014 Nov 26) | Ferrarotti I | Orphanet J Rare Dis |
| 24930071 | Unexpected inverse relationship between impaired glucose metabolism and lipoprotein-associated phospholipase A2 activity in patients with stable vascular disease. (2014 Jul) | Mayer O Jr | Eur J Intern Med |
| 10803663 | Plasma lipoprotein(a) distribution and its correlates among Samoans. (2000 Apr) | Kamboh MI | Hum Biol |
| 15946696 | Nicotine affects mineralized nodule formation by the human osteosarcoma cell line Saos-2. (2005 Sep 16) | Tanaka H | Life Sci |
| 21316260 | Targeting phosphoinositide 3-kinase signalling in lung cancer. (2011 Nov) | Wojtalla A | Crit Rev Oncol Hematol |
| 15581963 | The effect of methylenetetrahydrofolate reductase polymorphism C677T on cervical cancer in Korean women. (2004 Dec) | Sull JW | Gynecol Oncol |
| 23635368 | Plasma adiponectin concentrations are associated with dietary glycemic index in Malaysian patients with type 2 diabetes. (2013) | Loh BI | Asia Pac J Clin Nutr |
| 25037242 | Hypoadiponectinemia correlates with arterial stiffness in kidney transplantation patients. (2015 Jun) | Ho GJ | Clin Exp Nephrol |
| 12472994 | Interactions between stress, interleukin-1beta, interleukin-6 and cortisol in periodontally diseased patients. (2002 Nov) | Mengel R | J Clin Periodontol |
| 12212789 | Genetic and environmental risk factors for Alzheimer's disease in Israeli Arabs. (2002 Aug-Oct) | Bowirrat A | J Mol Neurosci |
| 26405456 | The relationship between brain-derived neurotrophic factor and cognitive functions in alcohol-dependent patients: a preliminary study. (2015) | Han C | Ann Gen Psychiatry |
| 25575296 | Differentiated embryonic chondrocytes 1 expression of periodontal ligament tissue and gingival tissue in the patients with chronic periodontitis. (2015 Apr) | Hu S | Arch Oral Biol |
| 16947780 | Association of HLA-C3 and smoking with vasculitis in patients with rheumatoid arthritis. (2006 Sep) | Turesson C | Arthritis Rheum |
| 23167377 | Serum level of MMP-3 in patients with oral squamous cell carcinoma--lack of association with clinico-pathological features. (2012) | Tadbir AA | Asian Pac J Cancer Prev |
| 29520592 | Decrease of cocaine, but not heroin, self-administration and relapse by the tyrosine kinase inhibitor masitinib in male Sprague Dawley rats. (2018 May) | Belin-Rauscent A | Psychopharmacology (Berl) |
| 10064122 | Distribution of serum creatine kinase activity in young healthy persons. (1999 Jan) | Lev EI | Clin Chim Acta |
| 15209961 | Serum leptin level in children with atopic dermatitis-treated topical steroids. (2004 Jun) | Bostanci I | Pediatr Allergy Immunol |
| 24792900 | Combined effect between CHRNB3-CHRNA6 region gene variant (rs6474412) and smoking in psoriasis vulgaris severity. (2014 Jul 10) | Zhu KJ | Gene |
| 21552119 | Detection of high-risk HPV in head and neck squamous cell carcinomas: comparison of chromogenic in situ hybridization and a reverse line blot method. (2011 Dec) | Stevens TM | Appl Immunohistochem Mol Morphol |
| 27739341 | Is the molecular clock ticking differently in bipolar disorder? Methylation analysis of the clock gene ARNTL. (2016 Oct 14) | Bengesser SA | World J Biol Psychiatry |
| 16449870 | Long-term influence of a health education programme on knowledge and health behaviour in children. (2006 Feb) | Lindberg LC | Eur J Cardiovasc Prev Rehabil |
| 19879865 | Evidence for the involvement of matrix metalloproteinases in the cardiovascular effects produced by nicotine. (2010 Feb 10) | Jacob-Ferreira AL | Eur J Pharmacol |
| 26860188 | Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis. (2016 Feb 9) | Liao K | J Neuroinflammation |
| 27644676 | Promoter Methylation and Relative mRNA Expression of the p16 Gene in Cervical Cancer in North Indians. (2016) | Gupta A | Asian Pac J Cancer Prev |
| 26958331 | Serum C-reactive protein in asthma and its ability in predicting asthma control, a case-control study. (2016 Winter) | Monadi M | Caspian J Intern Med |
| 15365303 | Multicenter validation study of the %CDT TIA kit in alcohol abuse and alcohol dependence. (2004 Sep) | Schwan R | Alcohol Clin Exp Res |
| 26223296 | Assessment of anti-Mullerian hormone levels in premenopausal patients with systemic lupus erythematosus. (2016 Mar) | Gasparin AA | Lupus |
| 12762340 | Increased inflammatory markers in the exhaled breath condensate of cigarette smokers. (2003 Apr) | Carpagnano GE | Eur Respir J |
| 17062156 | Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells. (2006 Oct 24) | Kode A | Respir Res |
| 25126948 | Association of DNA methyltransferases 3A and 3B polymorphisms, and plasma folate levels with the risk of urothelial carcinoma. (2014) | Chung CJ | PLoS One |
| 15575240 | Association between serum C-reactive protein levels and microalbuminuria: a population-based cross-sectional study in northern Iwate, Japan. (2004 Oct) | Nakamura M | Intern Med |
| 25494110 | Serum levels of interleukin-7 and interleukin-8 in head and neck squamous cell carcinoma. (2014 July-September) | Mojtahedi Z | Indian J Cancer |
| 28241675 | [Association between single nucleotide polymorphismsin human heat shock protein 70 gene and susceptibility to noise-induced hearing loss]. (2016 Dec 20) | Li YH | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi |
| 10803776 | Biological markers of alcoholism with respect to genotypes of low-Km aldehyde dehydrogenase (ALDH2) in Japanese subjects. (2000 Apr) | Nomura F | Alcohol Clin Exp Res |
| 23991993 | B-cell Lymphoma 2 rs17757541 C>G polymorphism was associated with an increased risk of gastric cardiac adenocarcinoma in a Chinese population. (2013) | Li Q | Asian Pac J Cancer Prev |
| 22186711 | Interaction of HLA-DRB1*03 and smoking for the development of anti-Jo-1 antibodies in adult idiopathic inflammatory myopathies: a European-wide case study. (2012 Jun) | Chinoy H | Ann Rheum Dis |
| 7473968 | Relevance of carbohydrate-deficient transferrin as a predictor of alcoholism in intensive care patients following trauma. (1995 Oct) | Spies CD | J Trauma |
| 12390313 | Direct modulatory effect of C-reactive protein on primary human monocyte adhesion to human endothelial cells. (2002 Nov) | Woollard KJ | Clin Exp Immunol |
| 19205928 | Circulating anti-heat-shock-protein antibodies in normal pregnancy and preeclampsia. (2009 Sep) | Molvarec A | Cell Stress Chaperones |
| 28697900 | The distribution of human papillomavirus genotypes in cervical cancer and intraepithelial neoplasia lesions among Chinese women in Yunnan Province. (2018 Jan - Feb) | Yuanyue L | J Infect Public Health |
| 18029191 | Genetic polymorphisms and plasma levels of transforming growth factor-beta(1) in Chinese patients with tuberculosis in Hong Kong. (2007 Dec) | Mak JC | Cytokine |
| 22211795 | Not all elderly people benefit from vitamin D supplementation with respect to physical function: results from the Osteoporotic Fractures in Men Study, Hong Kong. (2012 Feb) | Chan R | J Am Geriatr Soc |
| 24782217 | Role of inflammatory parameters in the susceptibility of cerebral thrombosis. (2014 Apr 16) | Qi XF | Genet Mol Res |
| 28123559 | Cervical intraepithelial neoplasia in pregnancy: Interference of pregnancy status with p16 and Ki-67 protein expression. (2017 Jan) | Ciavattini A | Oncol Lett |
| 24441222 | Association of Epstein Barr virus deoxyribonucleic acid with lung carcinoma. (2013 Oct-Dec) | Jafarian AH | Indian J Pathol Microbiol |
| 26108072 | Association of urine CC16 and lung function and asthma in Chinese children. (2015 Jul-Aug) | Ma YN | Allergy Asthma Proc |
| 23726808 | Interleukin 1B rs16944 G>A polymorphism was associated with a decreased risk of esophageal cancer in a Chinese population. (2013 Oct) | Zheng L | Clin Biochem |
| 9086297 | Serum carbohydrate-deficient transferrin in patients with nonalcoholic liver disease and with hepatocellular carcinoma. (1997 Mar 18) | Murawaki Y | Clin Chim Acta |
| 17007051 | Improved method of plasma 8-Isoprostane measurement and association analyses with habitual drinking and smoking. (2006 Sep 28) | Kitano S | World J Gastroenterol |
| 16617357 | [Change and clinical implication of urotensin II in plasma and induced sputum of chronic obstructive pulmonary disease]. (2006 Apr 18) | Lu M | Beijing Da Xue Xue Bao Yi Xue Ban |
| 28728277 | [Effects of PI3Kdelta-RhoA pathway on phagocytosis defect of alveolar macrophages in a mouse model of chronic obstructive pulmonary disease]. (2017 Jul 12) | Hu ST | Zhonghua Jie He He Hu Xi Za Zhi |
| 23476107 | Cigarette smoke suppresses the surface expression of c-kit and FcepsilonRI on mast cells. (2013) | Givi ME | Mediators Inflamm |
| 14764959 | Effect of smoking on serum concentrations of total homocysteine, folate, vitamin B12, and nitric oxide in pregnancy: a preliminary study. (2004 Mar-Apr) | Ozerol E | Fetal Diagn Ther |
| 27284701 | Relationship between ABCB1 polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT). (2016 Sep) | Zahari Z | Am J Drug Alcohol Abuse |
| 25297392 | An association study on the CHRNA5/A3/B4 gene cluster, smoking and psoriasis vulgaris. (2014 Dec) | Zhu KJ | Arch Dermatol Res |
| 29704590 | Protective influences of N-acetylcysteine against alcohol abstinence-induced depression by regulating biochemical and GRIN2A, GRIN2B gene expression of NMDA receptor signaling pathway in rats. (2018 Apr 25) | Yawalkar R | Neurochem Int |
| 21643870 | Increased heat shock protein 70 levels in induced sputum and plasma correlate with severity of asthma patients. (2011 Nov) | Hou C | Cell Stress Chaperones |
| 21930150 | Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. (2011 Dec) | Hauser SR | Pharmacol Biochem Behav |
| 25122436 | Clinical characteristics, tumor, node, metastasis status, and mutation rate in domain of epidermal growth factor receptor gene in serbian patients with lung adenocarcinoma. (2014 Sep) | Zaric B | J Thorac Oncol |
| 9524389 | Staging of adult smokers according to the transtheoretical model of behavioural change: analysis of an eastern Ontario cohort. (1998 Jan-Feb) | Pickett W | Can J Public Health |
| 12812142 | Negative association between smoking and anti-saccharomyces cerevisiae antibodies in Crohn's disease. (2003 Jan-Mar) | Van Kemseke C | Acta Gastroenterol Belg |
| 25217982 | Essential role of polymorphism of Gab1, EGFR, and EGF for the susceptibility of biliary tract cancer. (2014 Dec) | Meng LQ | Tumour Biol |
| 23895419 | Interleukin 17A rs4711998 A>G polymorphism was associated with a decreased risk of esophageal cancer in a Chinese population. (2014 Jan) | Yin J | Dis Esophagus |
| 24649266 | Exploratory study on the correlation between 14 lung cancer-related gene expression and specific clinical characteristics of NSCLC patients. (2013 Sep) | Han Y | Mol Clin Oncol |
| 12362501 | [E selectin of blood in patients with unstable angina pectoris]. (2002 Jul) | Grabarczyk E | Pol Merkur Lekarski |
| 27318899 | [Association between grainyhead-like 2 gene polymorphisms and noise-induced hearing loss]. (2016 Jun 18) | Yang QY | Beijing Da Xue Xue Bao Yi Xue Ban |
| 29515441 | Autophagy Flux Contributes to Regulation of Components of Eclipta prostrata L. on Cigarette Smoking-Induced Injury of Bronchial Epithelial Cells. (2018) | Ding S | Front Pharmacol |
| 28534101 | Evaluation of ALK gene rearrangement in central nervous system metastases of non-small-cell lung cancer using two-step RT-PCR technique. (2017 Dec) | Nicos M | Clin Transl Oncol |
| 12059985 | Complement activating antibodies against the human 60 kDa heat shock protein as a new independent family risk factor of coronary heart disease. (2002 Jun) | Veres A | Eur J Clin Invest |
| 24782418 | You have been QUALIFIED for a smokeless e-cig starter kit. (2014 Aug) | Hunt K | J Epidemiol Community Health |
| 17346294 | IL13 gene polymorphism association with cord serum immunoglobulin E. (2007 Jun) | Sadeghnejad A | Pediatr Allergy Immunol |
| 16251120 | N-acetyltransferase 2 phenotype may be associated with susceptibility to age-related cataract. (2005 Oct) | Tamer L | Curr Eye Res |
| 24140751 | Quantification of secretory leukocyte protease inhibitor (SLPI) in oral gargle specimens collected using mouthwash. (2013 Dec 31) | Pierce Campbell CM | J Immunol Methods |
| 28104537 | Correlation between Classic Driver Oncogene Mutations in EGFR, ALK, or ROS1 and 22C3-PD-L1 >/=50% Expression in Lung Adenocarcinoma. (2017 May) | Rangachari D | J Thorac Oncol |
| 25013472 | Relative influence of c-Kit expression and epidermal growth factor receptor gene amplification on survival in patients with non-small cell lung cancer. (2014 Aug) | Xiao H | Oncol Lett |
| 11257732 | Thrombomodulin--endothelial thrombin receptor in blood of patients with unstable angina pectoris. (2001 Mar-Apr) | Wisniewska E | Med Sci Monit |
| 17494790 | Relationship between serum substance P levels and daytime sleepiness in obstructive sleep apnea syndrome. (2007 May) | Ursavas A | Chest |
| 22670177 | An immunohistochemical and molecular genetic analysis of KIT and PDGFRA in small cell lung carcinoma in Japanese. (2012) | Terada T | Int J Clin Exp Pathol |
| 29133146 | Association of genetic polymorphisms with erythrocyte traits: Verification of SNPs reported in a previous GWAS in a Japanese population. (2018 Feb 5) | Seiki T | Gene |
| 21697514 | Xenobiotic effects on ovarian preantral follicles. (2011 Nov) | Mark-Kappeler CJ | Biol Reprod |
| 28977375 | Cross-Sectional and Longitudinal Relationships Between Inflammatory Biomarkers and Frailty in Community-dwelling Older Men: The Concord Health and Ageing in Men Project. (2017 Jul 28) | Hsu B | J Gerontol A Biol Sci Med Sci |
| 29246019 | Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study. (2017 Nov 21) | Liu R | Oncotarget |
| 17368733 | Targeting receptor tyrosine kinase signalling in small cell lung cancer (SCLC): what have we learned so far? (2007 Jun) | Fischer B | Cancer Treat Rev |
| 15617035 | N-acetyltransferase 2 gene polymorphism in patients with colorectal carcinoma. (2006 Mar-Apr) | Tamer L | Cell Biochem Funct |
| 26200230 | Decreased brain-derived neurotrophic factor plasma levels in psoriasis patients. (2015 Aug) | Brunoni AR | Braz J Med Biol Res |
| 24492497 | 2-ethylpyridine, a cigarette smoke component, causes mitochondrial damage in human retinal pigment epithelial cells in vitro. (2014 Jan) | Mansoor S | Indian J Ophthalmol |
| 29603693 | Assessment of Salivary Catalase, a-Amylase, and Cotinine Levels in Chronic Smokers: A Comparative Study. (2018 Mar 1) | Singh S | J Contemp Dent Pract |
| 28325255 | Mucosal melanoma of the head and neck. (2017 Apr) | Ascierto PA | Crit Rev Oncol Hematol |
| 11125855 | Factors affecting serum haloperidol level assessed by longitudinal therapeutic monitoring. (2000 Nov) | Fukuda R | Prog Neuropsychopharmacol Biol Psychiatry |
| 27016010 | Salivary secretory leukocyte protease inhibitor (SLPI) and head and neck cancer: The Cancer Prevention Study II Nutrition Cohort. (2016 Apr) | Pierce Campbell CM | Oral Oncol |
| 22475777 | Association between PPAR-gamma and RXR-alpha gene polymorphism and metabolic syndrome risk: a case-control study of a Chinese Han population. (2012 Apr) | Shi H | Arch Med Res |
| 25260414 | The p-ERK-p-c-Jun-cyclinD1 pathway is involved in proliferation of smooth muscle cells after exposure to cigarette smoke extract. (2014 Oct 24) | Li T | Biochem Biophys Res Commun |
| 23438328 | Systemic inflammation is associated with differential gene expression and airway neutrophilia in asthma. (2013 Apr) | Fu JJ | OMICS |
| 25007143 | Pulmonary adenocarcinoma with signet ring cell features: a comprehensive study from 3 distinct patient cohorts. (2014 Dec) | Boland JM | Am J Surg Pathol |
| 11479694 | Evaluation of Cyfra 21-1: a potential tumor marker for non-small cell lung carcinomas. (2001) | Karnak D | Lung |
| 24749767 | Roles of the ALDH2 and ADH1B genotypes on the association between alcohol intake and serum adiponectin levels among Japanese male workers. (2014 Jun) | Maeda S | Alcohol Clin Exp Res |
| 17095166 | Evidence of an association of leptin serum levels and craving in alcohol dependence. (2007 Jan) | Hillemacher T | Psychoneuroendocrinology |
| 29332331 | EGFR mutations and tumor metastases in patients with nonsmall cell lung cancer in the South of Russia. (2017 Nov-Dec) | Kit OI | J BUON |
| 16805752 | Bax, bcl-2 and c-kit expression in non-small-cell lung cancer and their effects on prognosis. (2006 Jun) | Yaren A | Int J Clin Pract |
| 26199924 | Inverse Correlation between Serum C-Reactive Protein and Magnesium Levels in Smokers and Nonsmokers. (2015 Jun) | Ata MA | N Am J Med Sci |
| 21623266 | EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery. (2011 May) | Helland A | J Thorac Oncol |
| 25436132 | Bilateral above knee amputations after prolonged exposure to sorafenib and trebananib. (2014 Dec) | Haque S | J Gastrointest Oncol |
| 28337899 | Substance P expression in the gingival tissue after upper third molar extraction: effect of ketoprofen, a preliminary study. (2017 Jan-Mar) | Abbate GM | J Biol Regul Homeost Agents |
| 19544167 | Smoking affects eotaxin levels in asthma patients. (2009 Jun) | Krisiukeniene A | J Asthma |
| 9916968 | Association between bacterial vaginosis and fetal fibronectin at 24-29 weeks' gestation. (1999 Jan) | Pastore LM | Obstet Gynecol |
| 25024542 | Salivary TNF-alpha: A potential marker of periodontal destruction. (2014 May) | Singh P | J Indian Soc Periodontol |
| 14692803 | Bronchial epithelial-myoepithelial carcinoma. (2004 Jan) | Ru K | Arch Pathol Lab Med |
| 23876628 | Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer. (2013 Sep) | Sinha N | Oral Oncol |
| 26793845 | EGFR MUTATIONS IN NON-SMALL CELL LUNG CANCER: LOCAL EPIDEMIOLOGY AND CLINICAL IMPORTANCE. (2015 Oct-Dec) | Rusu-Cordunean F | Rev Med Chir Soc Med Nat Iasi |
| 27821168 | Associations of proteins relevant to MAPK signaling pathway (p38MAPK-1,HIF-1 and HO-1) with coronary lesion characteristics and prognosis of peri-menopausal women. (2016 Nov 8) | Yan L | Lipids Health Dis |
| 10641749 | p21WAF1 protein expression determined by quantitative immunoassay in relation to non-small-cell lung cancer aggressiveness. (2000 Jan) | Levesque MA | J Cancer Res Clin Oncol |
| 19394604 | Cigarette smoking affects specific sperm oxidative defenses but does not cause oxidative DNA damage in infertile men. (2010 Jul) | Viloria T | Fertil Steril |
| 29027939 | Nicotine Component of Cigarette Smoke Extract (CSE) Decreases the Cytotoxicity of CSE in BEAS-2B Cells Stably Expressing Human Cytochrome P450 2A13. (2017 Oct 13) | Ji M | Int J Environ Res Public Health |
| 14982605 | Determinants of BMI in patients with COPD. (2004 Mar) | Karadag F | Respirology |
| 17332488 | Circulating apoptotic progenitor cells: a novel biomarker in patients with acute coronary syndromes. (2007 May) | Schwartzenberg S | Arterioscler Thromb Vasc Biol |
| 16266509 | [Analysis of serum glutathione S-transferase and urinary 8-hydroxy-2-deoxyguanosine in coke oven workers]. (2005 Oct) | Liu AL | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi |
| 17934972 | Associations of methylenetetrahydrofolate reductase C677T polymorphism with markers of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study. (2008) | Collings A | Scand J Clin Lab Invest |
| 22443498 | Histone deacetylase activity is decreased in peripheral blood monocytes in patients with COPD. (2012 Mar 23) | Chen Y | J Inflamm (Lond) |
| 12499705 | Chlamydia pneumoniae in elderly patients with stroke (C-PEPS): a case-control study on the seroprevalence of Chlamydia pneumoniae in elderly patients with acute cerebrovascular disease. (2003) | Ngeh J | Cerebrovasc Dis |
| 29650325 | Improving the genetic signature of prostate cancer, the somatic mutations. (2018 Jun) | Martinez-Gonzalez LJ | Urol Oncol |
| 15328987 | p53 aberrations in oral sub mucous fibrosis and oral cancer detected by immunohistochemistry. (2003 Oct-Dec) | Bathi RJ | Indian J Dent Res |
| 27021533 | The effect of type 2 diabetes mellitus and smoking on periodontal parameters and salivary matrix metalloproteinase-8 levels. (2016) | Gupta N | J Oral Sci |
| 29281903 | Assessment of FGFR1 Over-Expression and Over-Activity in Lung Cancer Cells: A Toolkit for Anti-FGFR1 Drug Screening. (2018 Feb) | Hu P | Hum Gene Ther Methods |
| 16842481 | Hormone replacement therapy is associated with increased C-reactive protein in women with Type 2 diabetes in the Diabetes Heart Study. (2006 Jul) | Bowden DW | Diabet Med |
| 24793809 | alpha5 Nicotinic acetylcholine receptor mediates nicotine-induced HIF-1alpha and VEGF expression in non-small cell lung cancer. (2014 Jul 15) | Ma X | Toxicol Appl Pharmacol |
| 27834689 | Nicotine Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice by Activating alpha7 Nicotinic Acetylcholine Receptor on Mast Cells. (2017 Jan) | Wang C | Arterioscler Thromb Vasc Biol |
| 27326007 | Smoking is associated with reduced serum paraoxonase, antioxidants and increased oxidative stress in normolipidaemic acute myocardial infarct patients. (2011) | Kumar A | Heart Asia |
| 23792053 | MiR-196a2 rs11614913 T > C polymorphism and risk of esophageal cancer in a Chinese population. (2013 Sep) | Wei J | Hum Immunol |
| 25109408 | Hotspot mutations in common oncogenes are infrequent in nasopharyngeal carcinoma. (2014 Oct) | Jiang N | Oncol Rep |
| 27900249 | The influence of smoking on the levels of matrix metalloproteinase-8 and periodontal parameters in smoker and nonsmoker patients with chronic periodontitis: A clinicobiochemical study. (2016 Nov) | Gupta N | J Oral Biol Craniofac Res |
| 18453780 | Serum asymmetric dimethylarginine levels among Turks: association with metabolic syndrome in women and tendency to decrease in smokers. (2008 Jan) | Onat A | Turk Kardiyol Dern Ars |
| 23672176 | [Strategies for Mycobacterium avium complex infection control in Japan: how do they improve the present situation?]. (2013 Mar) | Ogawa K | Kekkaku |
| 24342929 | Apparently "low" serum asymmetric dimethylarginine is associated with fasting glucose and tends toward association with type-2 diabetes. (2014 Feb) | Onat A | Anadolu Kardiyol Derg |
| 23067264 | Increased gingival crevicular fluid levels of soluble triggering receptor expressed on myeloid cells (sTREM) -1 in severe periodontitis. (2012 Dec) | Bisson C | J Clin Periodontol |
| 21875606 | Impaired nucleotide excision repair pathway as a possible factor in pathogenesis of head and neck cancer. (2011 Nov 1) | Sliwinski T | Mutat Res |
| 27920412 | Leptin and calorie intake among different nicotine dependent groups. (2016 Nov-Dec) | Suhaimi MZ | Ann Saudi Med |
| 22043704 | [Effects of NF-kappaB on the expression of IL-8 in human bronchial epithelial cells induced by cigarette smoke condensates]. (2011 Sep) | Zhang Q | Wei Sheng Yan Jiu |
| 19822955 | Variations in serum transforming growth factor-beta1 levels with gender, age and lifestyle factors of healthy Japanese adults. (2009) | Lin Y | Dis Markers |
| 25059375 | [Association between polymorphism of ATP2B1 gene, its interaction with smoking and essential hypertension -a case-control study]. (2014 May) | Song J | Zhonghua Liu Xing Bing Xue Za Zhi |
| 25052186 | Combined effects of the BDNF rs6265 (Val66Met) polymorphism and environment risk factors on psoriasis vulgaris. (2014 Oct) | Quan C | Mol Biol Rep |
| 23786491 | C-Kit/c-Kit ligand interaction of bone marrow endothelial progenitor cells is influenced in a cigarette smoke extract-induced emphysema model. (2013 Aug) | He S | Exp Lung Res |
| 16238106 | Genetic polymorphism of GSTM1 in women with breast cancer and interact with reproductive history and several clinical pathologies. (2005) | Linhares JJ | Biol Res |