Gene: ARG2

384
-
arginase 2
protein-coding
14q24.1
Ensembl:ENSG00000081181 MIM:107830 Vega:OTTHUMG00000171807 UniprotKB:P78540
NG_011964.1
PubMed
ND
3   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.922e-1 (AD)  8.834e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HCCS0.844
KLHL180.836
ARHGEF30.835
RNF19B0.834
NKRF0.833
ASPHD20.833
UGCG0.83
RASSF50.829
NRBF20.829
TRMT120.824

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MYOM1-0.504
ASB4-0.47
COPZ2-0.468
P2RY14-0.466
CTNNA3-0.461
STON2-0.46
HEY2-0.451
PARD3B-0.445
DOCK1-0.441
MBNL3-0.436

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ARG2 mRNA"25614096
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of ARG2 mRNA"19095052
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 protein]24951775
C1212282-amino-6-boronohexanoic acid2-amino-6-boronohexanoic acid binds to ARG2 protein21728378
C1212282-amino-6-boronohexanoic acid2-amino-6-boronohexanoic acid results in decreased activity of ARG2 protein15248756
C425062(2-boronoethyl)-cysteine(2-boronoethyl)-cysteine binds to ARG2 protein21728378
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARG2 mRNA"27188386
C0652504-hydroxy-equilenin4-hydroxy-equilenin results in decreased expression of ARG2 mRNA15135645
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARG2 mRNA"27188386
C0776467,12-benz(a)anthraquinone"7,12-benz(a)anthraquinone results in increased expression of ARG2 mRNA"26141390
C0776467,12-benz(a)anthraquinone"AHR2 affects the reaction [7,12-benz(a)anthraquinone results in increased expression of ARG2 mRNA]"26141390
D000082AcetaminophenAcetaminophen affects the expression of ARG2 mRNA25704631
D000082AcetaminophenAcetaminophen results in increased expression of ARG2 mRNA21420995|2223033
D000082AcetaminophenAcetaminophen affects the expression of ARG2 mRNA17562736
C006418adrenocorticotropin zincadrenocorticotropin zinc results in increased expression of ARG2 mRNA19920212
D016604Aflatoxin B1Aflatoxin B1 affects the expression of ARG2 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of ARG2 mRNA21632981|2164198
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of ARG2 mRNA19770486
D000643Ammonium ChlorideAmmonium Chloride affects the expression of ARG2 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of ARG2 mRNA"22863853
D001151ArsenicArsenic results in decreased expression of ARG2 mRNA19654921
C015001arsenitearsenite results in decreased expression of ARG2 mRNA18929588
C015001arseniteTRP53 protein affects the reaction [arsenite results in decreased expression of ARG2 mRNA]18929588
D001280AtrazineAtrazine results in decreased expression of ARG2 mRNA25929836
D001280AtrazineAtrazine results in decreased expression of ARG2 mRNA22378314
C547126AZM551248AZM551248 results in increased expression of ARG2 mRNA22323515
C012768benzanthroneAHR2 affects the reaction [benzanthrone results in increased expression of ARG2 mRNA]26141390
C012768benzanthronebenzanthrone results in increased expression of ARG2 mRNA26141390
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ARG2 mRNA21632981|2231617
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of ARG2 mRNA20660070
D004958EstradiolEstradiol results in increased expression of ARG2 mRNA20106945
D004958EstradiolEstradiol results in increased expression of ARG2 mRNA19484750
C053541bicalutamidebicalutamide results in increased expression of ARG2 protein20711410
C006780bisphenol Abisphenol A affects the expression of ARG2 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of ARG2 mRNA20170705
C006780bisphenol Abisphenol A results in increased expression of ARG2 mRNA27685785
C006780bisphenol Abisphenol A affects the expression of ARG2 mRNA25181051
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide affects the expression of ARG2 mRNA23410634
C018475butyraldehydebutyraldehyde results in increased expression of ARG2 mRNA26079696
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ARG2 mRNA17961207
D002737ChloropreneChloroprene results in increased expression of ARG2 mRNA23125180
D004390ChlorpyrifosChlorpyrifos results in increased expression of ARG2 mRNA21356183
C018021cobaltous chloridecobaltous chloride results in increased expression of ARG2 mRNA24612858
D003300CopperCopper results in decreased activity of ARG2 protein11916150
D019327Copper SulfateCopper Sulfate results in increased expression of ARG2 mRNA19549813
D003471CuprizoneCuprizone results in decreased expression of ARG2 mRNA26577399
D016572CyclosporineCyclosporine results in increased expression of ARG2 mRNA19159671|2010694
D003561CytarabineCytarabine results in decreased expression of ARG2 mRNA21198554
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of ARG2 mRNA24317228
D003907DexamethasoneDexamethasone results in increased expression of ARG2 mRNA14618091|2003205
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in increased expression of ARG2 mRNA]20032058
C016366dibenzothiophenedibenzothiophene results in increased expression of ARG2 mRNA23656968
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of ARG2 mRNA21266533
D002945CisplatinCisplatin results in increased expression of ARG2 mRNA27392435
D002945CisplatinCisplatin results in increased expression of ARG2 mRNA25270620
D002945CisplatinCisplatin results in increased expression of ARG2 mRNA22023808
C000944dicrotophosdicrotophos results in decreased expression of ARG2 mRNA28302478
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ARG2 mRNA24535843
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of ARG2 mRNA25242112
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ARG2 mRNA"22485181
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of ARG2 mRNA16314067
D004139DinitrofluorobenzeneDinitrofluorobenzene results in increased expression of ARG2 mRNA23999411
D004147DioxinsDioxins affects the expression of ARG2 mRNA20463971
D004317DoxorubicinDoxorubicin results in decreased expression of ARG2 mRNA28940058
D004785Environmental PollutantsEnvironmental Pollutants results in increased expression of ARG2 mRNA24534155
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of ARG2 mRNA16174780
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of ARG2 mRNA12655037|1583489
D005492Folic Acid[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ARG2 mRNA24657277
D005557FormaldehydeFormaldehyde results in increased expression of ARG2 mRNA27664576
C069837fullerene C60fullerene C60 results in decreased expression of ARG2 mRNA19167457
C039281furanfuran results in increased expression of ARG2 mRNA27387713
D005947GlucoseGlucose results in increased expression of ARG2 mRNA17178593
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of ARG2 mRNA22634610
C004312glycidolglycidol results in increased expression of ARG2 mRNA24915197
C412815GW 4064GW 4064 results in decreased expression of ARG2 mRNA26655953
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of ARG2 mRNA26846883
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of ARG2 mRNA23410634
C492448ICG 001ICG 001 results in increased expression of ARG2 mRNA26191083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARG2 mRNA25613284
C051890irinotecanirinotecan affects the expression of ARG2 mRNA20097248
D007529IsoflavonesIsoflavones results in decreased expression of ARG2 mRNA17374662
D048628KetolidesKetolides analog results in decreased expression of ARG2 mRNA24967691
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of ARG2 mRNA18557954
D008094LithiumLithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]19149911
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ARG2 mRNA26378955
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in increased expression of ARG2 mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ARG2 mRNA26378955
D008627Mercuric ChlorideARG2 protein results in decreased susceptibility to Mercuric Chloride17874066
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of and results in decreased activity of ARG2 protein17874066
D008628MercuryMercury results in decreased activity of ARG2 protein11916150
D008694MethamphetamineLithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]19149911
D008694MethamphetamineMethamphetamine results in increased expression of ARG2 mRNA19149911
D008694MethamphetamineValproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]19149911
D008727Methotrexate[Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ARG2 mRNA24657277
D008727MethotrexateMethotrexate results in increased expression of ARG2 mRNA24657277
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ARG2 mRNA20061341
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ARG2 mRNA26011545
D008743Methyl ParathionMethyl Parathion results in increased expression of ARG2 mRNA22182705
D008743Methyl ParathionMethyl Parathion results in increased expression of ARG2 protein22182705
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of ARG2 mRNA24810058
D015741MetriboloneAR mRNA affects the reaction [Metribolone results in increased expression of ARG2 protein]20711410
D015741MetriboloneCXCL8 mRNA affects the reaction [Metribolone results in increased expression of ARG2 protein]20711410
D015741MetriboloneMetribolone results in increased expression of ARG2 mRNA20711410
D015741MetriboloneMetribolone results in increased expression of ARG2 protein20711410
D009020MorphineMorphine promotes the reaction [Zymosan results in increased expression of ARG2 mRNA]18760300
C523799MRK 003ARG2 results in increased susceptibility to MRK 00319903844
C500085muraglitazarmuraglitazar results in decreased expression of ARG2 mRNA21515302
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of ARG2 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of ARG2 mRNA"25554681
C031721naphthalenenaphthalene results in increased expression of ARG2 mRNA18978301
D009532NickelNickel results in decreased expression of ARG2 mRNA24084258
C029938nickel sulfatenickel sulfate results in increased expression of ARG2 mRNA16314067
D009943Organophosphorus CompoundsOrganophosphorus Compounds results in increased expression of ARG2 protein23557688
D010081OxazoloneOxazolone results in increased expression of ARG2 mRNA23999411
D010100Oxygen2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 protein]24951775
D010100OxygenOxygen deficiency results in increased expression of ARG2 mRNA20042640|2342462
D010100OxygenOxygen deficiency results in increased expression of ARG2 protein23424623|2495177
D010100Oxygenresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 mRNA]24951775
D010100Oxygenresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 protein]24951775
D010126OzoneOzone results in increased expression of ARG2 mRNA17095637
D010126OzoneTTPA protein affects the reaction [Ozone results in increased expression of ARG2 mRNA]19555225
D010269ParaquatParaquat results in increased expression of ARG2 mRNA16854511|2038854
D052638Particulate MatterARG2 protein affects the reaction [Particulate Matter results in increased activity of CASP3 protein]26989813
D052638Particulate MatterParticulate Matter results in increased expression of ARG2 mRNA26989813
D052638Particulate MatterParticulate Matter results in increased expression of ARG2 mRNA21708214
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of ARG2 mRNA19095052
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of ARG2 mRNA23602845
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of ARG2 mRNA23978341
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of ARG2 protein26879310
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of ARG2 mRNA17097637
D010575PesticidesPesticides results in increased expression of ARG2 protein23557688
D010634PhenobarbitalPhenobarbital affects the expression of ARG2 mRNA19159669
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ARG2 mRNA24535843
D010705PhosgenePhosgene affects the expression of ARG2 mRNA16300373
D010938Plant OilsPlant Oils results in increased expression of ARG2 mRNA23370395
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of ARG2 mRNA27989595
D017035PravastatinPravastatin results in increased expression of ARG2 mRNA27225895
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of ARG2 mRNA20660070
D011374ProgesteroneProgesterone results in decreased expression of ARG2 mRNA22238285
C045950propiconazolepropiconazole results in increased expression of ARG2 mRNA21278054
C005556propionaldehydepropionaldehyde results in increased expression of ARG2 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in increased expression of ARG2 mRNA24780913
D011794QuercetinQuercetin results in increased expression of ARG2 mRNA21632981
D015125OxyquinolineOxyquinoline results in increased expression of ARG2 mRNA21632981
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of ARG2 mRNA22841776
C059514resveratrolresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 mRNA]24951775
C059514resveratrolresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 protein]24951775
D015474IsotretinoinIsotretinoin results in decreased expression of ARG2 mRNA20436886
C093642SB 203580SB 203580 inhibits the reaction [AGT protein modified form results in increased expression of ARG2 protein]21289285
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in decreased expression of ARG2 mRNA12818353
D012643SeleniumSelenium results in decreased expression of ARG2 mRNA19244175
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of ARG2 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in increased expression of ARG2 mRNA23221170
C017947sodium arsenitesodium arsenite affects the methylation of ARG2 gene28589171
C017947sodium arsenitesodium arsenite results in increased expression of ARG2 mRNA18812580
D012969Sodium FluorideSodium Fluoride results in decreased expression of ARG2 mRNA27862939
D012969Sodium FluorideSodium Fluoride results in increased expression of ARG2 protein28918527
D012999SomanSoman results in decreased expression of ARG2 mRNA19281266
D053260SootSoot results in increased expression of ARG2 mRNA22461453|2655175
C075117squalestatin 1squalestatin 1 results in increased expression of ARG2 mRNA27225895
C075117squalestatin 1squalestatin 1 results in decreased expression of ARG2 mRNA27225895
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ARG2 mRNA26378955
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in increased expression of ARG2 mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ARG2 mRNA26378955
D013629TamoxifenTamoxifen results in increased expression of ARG2 mRNA22841776
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in increased expression of ARG2 mRNA]20032058
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ARG2 mRNA17961207
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ARG2 mRNA18495758|2320411
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ARG2 mRNA20106945|2163298
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ARG2 mRNA21570461|2637764
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ARG2 mRNA19465110
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARG2 mRNA25613284
D019284ThapsigarginThapsigargin results in decreased expression of ARG2 mRNA22378314
D013853ThioacetamideThioacetamide results in increased expression of ARG2 mRNA23411599
C009495titanium dioxidetitanium dioxide results in increased expression of ARG2 mRNA23557971|2776080
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of ARG2 mRNA20133372
C483909torcetrapibtorcetrapib results in increased expression of ARG2 mRNA23228038
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARG2 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of ARG2 mRNA24935251|2627250
C012589trichostatin Atrichostatin A results in increased expression of ARG2 mRNA28542535
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of ARG2 mRNA16141432|1904294
C040533trimethyltin chloridetrimethyltin chloride results in increased expression of ARG2 mRNA23000284
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of ARG2 mRNA17982090
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of ARG2 mRNA"26179874
D014415TunicamycinTunicamycin results in decreased expression of ARG2 mRNA22378314
D014508UreaARG2 protein results in increased chemical synthesis of Urea17680661
D014635Valproic AcidValproic Acid affects the expression of ARG2 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of ARG2 mRNA23179753|2915479
D014635Valproic AcidValproic Acid affects the expression of ARG2 mRNA17963808
D014635Valproic AcidValproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]19149911
D014640VancomycinVancomycin results in decreased expression of ARG2 mRNA18930951
C025643vinclozolinvinclozolin affects the expression of ARG2 mRNA19015723
D024483Vitamin K 3Vitamin K 3 affects the expression of ARG2 mRNA23410634
D015032ZincZinc results in decreased expression of ARG2 mRNA20932299
D015032ZincZinc deficiency results in decreased expression of ARG2 mRNA11717422
C016837zinc chloridezinc chloride results in increased expression of ARG2 mRNA18947441
D015054ZymosanMorphine promotes the reaction [Zymosan results in increased expression of ARG2 mRNA]18760300
D015054ZymosanZymosan results in increased expression of ARG2 mRNA17988736|1876030

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004053arginase activity-EXP12859189  
GO:0004053arginase activity-IBA21873635  
GO:0004053arginase activity-IMP16128822  
GO:0030145manganese ion binding-IBA21873635  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000050urea cycle-IEA-  
GO:0000050urea cycle-TAS-  
GO:0001657ureteric bud development-IEA-  
GO:0002250adaptive immune response-IEA-  
GO:0002829negative regulation of type 2 immune response-IEA-  
GO:0006525arginine metabolic process-IEA-  
GO:0006809nitric oxide biosynthetic process-TAS8898077  
GO:0006941striated muscle contraction-IEA-  
GO:0019547arginine catabolic process to ornithine-IBA21873635  
GO:0032720negative regulation of tumor necrosis factor production-IMP28614294  
GO:0045087innate immune response-IEA-  
GO:0050706regulation of interleukin-1 beta secretion-IEA-  
GO:0071641negative regulation of macrophage inflammatory protein 1 alpha production-IEA-  
GO:0071644negative regulation of chemokine (C-C motif) ligand 4 production-IEA-  
GO:0071650negative regulation of chemokine (C-C motif) ligand 5 production-IEA-  
GO:1900425negative regulation of defense response to bacterium-IEA-  
GO:1903426regulation of reactive oxygen species biosynthetic process-IEA-  
GO:1904468negative regulation of tumor necrosis factor secretion-IEA-  
GO:1905077negative regulation of interleukin-17 secretion-IEA-  
GO:1905403negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process-IEA-  
GO:2000562negative regulation of CD4-positive, alpha-beta T cell proliferation-IEA-  
GO:2000666negative regulation of interleukin-13 secretion-IEA-  
GO:2000774positive regulation of cellular senescence-IDA22928666  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IBA21873635  
GO:0005739mitochondrion-IBA21873635  
GO:0005739mitochondrion-TAS8898077  
GO:0005759mitochondrial matrix-TAS-  
GO:0005829cytosol-IBA21873635  
KEGG ID KEGG Term
hsa00330Arginine and proline metabolism
hsa01100Metabolic pathways
hsa05146Amoebiasis
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-351202Metabolism of polyaminesTAS
R-HSA-70635Urea cycleTAS
R-HSA-71291Metabolism of amino acids and derivativesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24125417Contribution of arginase activation to vascular dysfunction in cigarette smoking. (2013 Nov)Sikka GAtherosclerosis
16387594Genetic polymorphisms in arginase I and II and childhood asthma and atopy. (2006 Jan)Li HJ Allergy Clin Immunol
19281908Roles of arginase variants, atopy, and ozone in childhood asthma. (2009 Mar)Salam MTJ Allergy Clin Immunol