Gene: KRT8

3856
CARD2|CK-8|CK8|CYK8|K2C8|K8|KO
keratin 8
protein-coding
12q13.13
Ensembl:ENSG00000170421 MIM:148060 Vega:OTTHUMG00000169881 UniprotKB:P05787
NG_008402.2
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.099e-1 (AD)  7.178e-2 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg10843343chr12:53298027KRT84.800e-8Smoking27651444
cg24504361chr12:53297987KRT86.700e-8Smoking27651444

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KRT180.684
HBG10.678
HOXB40.673
RHAG0.656
PRAME0.621
CTCFL0.612
HBG20.602
FAM83A0.598
IGF2BP10.596
SH2D3A0.572

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC25A10-0.335
CCDC87-0.312
ADCK1-0.309
F7-0.308
NEUROD6-0.302
E2F1-0.297
EXTL1-0.296
MYADML2-0.294
TPBGL-0.294
ANKRD24-0.293

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00031TenecteplaseBiotechDrug191588-94-0ApprovedTarget
DB06245LanoteplaseBiotechDrug171870-23-8InvestigationalTarget
DB09130CopperSmall Molecule7440-50-8Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in decreased expression of KRT8 mRNA"26377693
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of KRT8 mRNA"21346803
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of KRT8 mRNA25088246
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in decreased expression of KRT8 mRNA]28655636
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in decreased expression of KRT8 mRNA]28655636
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KRT8 mRNA"28973690
C5307733,5-diethoxycarbonyl-1,4-dihydrocollidine"3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of KRT8 mRNA"10751352
C5307733,5-diethoxycarbonyl-1,4-dihydrocollidine"KRT8 protein results in decreased susceptibility to 3,5-diethoxycarbonyl-1,4-dihydrocollidine"10751352
C4967514-(1H-imidazol-1-yl)retinoic acid4-(1H-imidazol-1-yl)retinoic acid results in increased expression of KRT8 protein17145897|1738734
C4967514-(1H-imidazol-1-yl)retinoic acid4-(1H-imidazol-1-yl)retinoic acid results in increased expression of KRT8 protein17145897
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of KRT8 mRNA"18648102
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of KRT8 mRNA"25380136
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of KRT8 protein"25670856
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of KRT8 mRNA"21346803
C0022024-oxoretinoic acid4-oxoretinoic acid results in increased expression of KRT8 mRNA17034753
C0418194-oxoretinol4-oxoretinol results in increased expression of KRT8 mRNA17034753
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of KRT8 mRNA21420995
D000082AcetaminophenAcetaminophen results in decreased expression of KRT8 protein22230336
D000082AcetaminophenAcetaminophen results in increased expression of KRT8 protein22230336
D000082AcetaminophenAcetaminophen affects the expression of KRT8 mRNA17562736
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of KRT8 mRNA17585979
D000082Acetaminophen[CTH gene mutant form results in increased susceptibility to Acetaminophen] which results in decreased expression of KRT8 protein25499718
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of KRT8 mRNA]17585979
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]15939799
D000171AcroleinAcrolein results in increased metabolism of KRT8 protein20015449
D000171AcroleinAcrolein results in increased phosphorylation of KRT8 protein24594012
D020106AcrylamideAcrylamide results in increased expression of KRT8 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of KRT8 gene27153756
C103303alitretinoinalitretinoin results in increased expression of KRT8 mRNA17034753
D000517alpha-Chlorohydrinalpha-Chlorohydrin analog results in decreased expression of KRT8 protein26597043
D000638AmiodaroneAmiodarone affects the expression of KRT8 mRNA19483382
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of KRT8 mRNA"22863853
D016718Arachidonic Acid[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein17034788
D001151ArsenicArsenic results in decreased expression of KRT8 mRNA11134558|1277377
C006632arsenic trioxidearsenic trioxide results in decreased expression of KRT8 protein25419056
C006632arsenic trioxideKRT8 protein results in decreased susceptibility to arsenic trioxide20707922
C015001arsenitearsenite results in decreased expression of KRT8 protein21344382
D001374AzacitidineAzacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]20823114
D001374AzacitidineAzacitidine results in increased expression of KRT8 mRNA20823114
D001507BeclomethasoneBeclomethasone results in increased expression of KRT8 mRNA23656298
D001553BenzbromaroneBenzbromarone affects the expression of KRT8 mRNA19483382
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of KRT8 protein17292933
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of KRT8 mRNA27195522
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [sodium arsenite results in decreased expression of KRT8 protein]16456883
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of KRT8 protein16456883
D001564Benzo(a)pyrenesodium arsenite promotes the reaction [Benzo(a)pyrene results in decreased expression of KRT8 protein]16456883
D019207beta Carotenebeta Carotene results in decreased expression of KRT8 mRNA17034753
D004958EstradiolAzacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]20823114
D004958Estradiol[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA20823114
D004958EstradiolEstradiol results in decreased expression of KRT8 mRNA16705744
D004958EstradiolEstradiol results in increased expression of KRT8 mRNA14605097
D004958EstradiolKRT8 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]20061804
D004958EstradiolEstradiol results in increased expression of KRT8 mRNA15289156|1948475
D004958Estradiol[bisphenol A co-treated with Estradiol] results in increased expression of KRT8 mRNA26496021
D004958EstradiolEstradiol results in decreased expression of KRT8 mRNA17522070
D001647Bile Acids and SaltsBile Acids and Salts results in increased expression of KRT8 protein21127259
C006780bisphenol Abisphenol A affects the expression of KRT8 mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of KRT8 mRNA22194820
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in increased expression of KRT8 mRNA26496021
C006780bisphenol Abisphenol A results in decreased expression of KRT8 mRNA29097150
C006780bisphenol Abisphenol A results in increased expression of KRT8 mRNA25181051
C423844BL 11282BL 11282 results in decreased expression of KRT8 protein17458497
C515564bromovaninbromovanin results in increased expression of KRT8 protein21419150
D002085ButylhydroxybutylnitrosamineButylhydroxybutylnitrosamine results in decreased expression of KRT8 protein24998975
D002104CadmiumKRT8 protein results in decreased susceptibility to Cadmium17332340
D019256Cadmium ChlorideCadmium Chloride results in increased expression of KRT8 mRNA22767353
D019256Cadmium Chloride[Methyl Parathion co-treated with Cadmium Chloride] results in increased expression of KRT8 mRNA22767353
D019256Cadmium Chloride[Methyl Parathion co-treated with Cadmium Chloride] results in increased expression of KRT8 protein22767353
D019256Cadmium ChlorideCadmium Chloride results in increased expression of KRT8 protein26220685
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of KRT8 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of KRT8 mRNA27339419
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of KRT8 mRNA17522070
D002330CarmustineKRT8 mRNA affects the susceptibility to Carmustine16365179
D002725ChloroformChloroform results in increased expression of KRT8 mRNA17522070
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of KRT8 mRNA26272509
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of KRT8 mRNA20938992
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of KRT8 mRNA24374135
C418118CI 1044CI 1044 results in increased expression of KRT8 mRNA17569694
C019304ciprofibrateciprofibrate results in increased expression of KRT8 mRNA12771043
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of KRT8 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of KRT8 mRNA]17585979
D002994ClofibrateClofibrate affects the expression of KRT8 mRNA19483382
D002994ClofibrateClofibrate results in decreased expression of KRT8 mRNA17522070
C018021cobaltous chloridecobaltous chloride results in decreased expression of KRT8 mRNA19376846
D003300CopperCopper results in increased expression of KRT8 protein22480594
D003300CopperKRT8 protein binds to Copper14534351
D019327Copper SulfateCopper Sulfate results in increased expression of KRT8 mRNA19549813
C015763cumene[cumene co-treated with KRAS gene mutant form] results in decreased expression of KRT8 mRNA18648096
D003471CuprizoneCuprizone results in increased expression of KRT8 mRNA26577399
C057862cyanoginosin LRcyanoginosin LR results in increased phosphorylation of and affects the expression of KRT8 protein22960429
C057862cyanoginosin LRSB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein]22960429
C057862cyanoginosin LRU 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein]22960429
C057862cyanoginosin LRcyanoginosin LR results in increased expression of KRT8 mRNA17654400
D003520CyclophosphamideCyclophosphamide results in decreased expression of KRT8 mRNA21621594
D016572CyclosporineCyclosporine results in increased expression of KRT8 mRNA21163907
D003561CytarabineCytarabine results in decreased expression of KRT8 mRNA21198554
D003630DaunorubicinDaunorubicin results in increased expression of KRT8 protein2444108
D003634DDTDDT results in decreased expression of KRT8 protein26186133
C014347decitabinedecitabine affects the expression of KRT8 protein19294695
C014347decitabine[trichostatin A co-treated with decitabine] results in decreased expression of KRT8 protein19294695
D003907DexamethasoneDexamethasone results in increased expression of KRT8 mRNA21621594
D003907DexamethasoneDexamethasone results in decreased expression of KRT8 mRNA17522070
C042577diallyl trisulfidediallyl trisulfide results in decreased expression of KRT8 protein16344271
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of KRT8 mRNA21266533
D003994BucladesineAzacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]20823114
D003994Bucladesine[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA20823114
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of KRT8 mRNA28962523
D004041Dietary FatsDietary Fats results in increased expression of KRT8 mRNA22609946
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT8 protein20101389
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of KRT8 mRNA12771043
D004052Diethylnitrosamine[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein18978307
D004052Diethylnitrosamine[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of KRT8 mRNA16158176
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of KRT8 mRNA14656948
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of and results in increased phosphorylation of KRT8 protein19409407
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KRT8 mRNA19409407
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of KRT8 mRNA28943392
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of KRT8 mRNA19638242
D004052Diethylnitrosamine[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein20935162
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of KRT8 mRNA15171707|2246701
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of KRT8 mRNA15289156
D0151279,10-Dimethyl-1,2-benzanthracene"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of KRT8 protein"22248470
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of KRT8 protein"22248470
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of KRT8 mRNA17072980|2538013
D004121Dimethyl SulfoxideDimethyl Sulfoxide results in increased expression of KRT8 mRNA22169935
D004237DiuronDiuron results in decreased expression of KRT8 mRNA21551480
D004317DoxorubicinDoxorubicin affects the expression of KRT8 protein29385562
C070609EMD 53998EMD 53998 analog results in decreased expression of KRT8 mRNA24977338
C013525ENNG[ENNG co-treated with Isoflavones] results in increased expression of KRT8 protein22248470
C013525ENNGENNG results in increased expression of KRT8 protein22248470
C118739entinostatentinostat results in increased expression of KRT8 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased methylation of KRT8 promoter27415467
D000431Ethanol[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein17034788
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of KRT8 protein20227414
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of KRT8 mRNA17942748|1940095
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRT8 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of KRT8 mRNA29097150
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of KRT8 mRNA15576828|1755790
D005001EthionineEthionine affects the expression of KRT8 mRNA19483382
C034814ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid"ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid results in increased expression of KRT8 protein"7505756
D011345Fenofibrate[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein18978307
C020326ferric nitrilotriacetate[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein17034788
C082360fipronilfipronil results in decreased expression of KRT8 mRNA23962444
C043562flavoneflavone results in increased expression of KRT8 protein14750173
D0150732-Acetylaminofluorene[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of KRT8 mRNA16158176
D0150732-Acetylaminofluorene[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of KRT8 mRNA14656948
D005485FlutamideFlutamide results in increased expression of KRT8 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of KRT8 mRNA20938992
C069837fullerene C60fullerene C60 results in increased expression of KRT8 mRNA19167457
C070081fulvestrantKRT8 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]20061804
C070081fulvestrantKRT8 protein promotes the reaction [fulvestrant results in increased degradation of ESR1 protein]20061804
C056933fumonisin B1fumonisin B1 results in increased expression of KRT8 mRNA16221962
C039281furanfuran binds to KRT8 protein22240984
C039281furanfuran results in increased expression of KRT8 mRNA25539665|2619464
C056507gemcitabinegemcitabine results in decreased expression of KRT8 mRNA17039268
D019833GenisteinESR1 promotes the reaction [Genistein results in increased expression of KRT8 protein]20884965
D019833GenisteinESR2 promotes the reaction [Genistein results in increased expression of KRT8 protein]20884965
D019833GenisteinGenistein results in decreased expression of KRT8 mRNA16705744
D019833GenisteinGenistein results in increased expression of KRT8 protein20884965
D019833GenisteinGenistein results in increased expression of KRT8 mRNA15289156|2436511
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of KRT8 mRNA22634610
D006118GriseofulvinGriseofulvin results in increased expression of KRT8 mRNA10952237|1273510
D006118GriseofulvinGriseofulvin results in increased expression of KRT8 protein10952237
D006118GriseofulvinGriseofulvin results in increased phosphorylation of KRT8 protein20643122
D017313FenretinideFenretinide results in increased expression of KRT8 protein17387344
D017313FenretinideFenretinide results in increased expression of KRT8 mRNA28973697
C029424hydrazinehydrazine results in increased expression of KRT8 protein15370871
C492448ICG 001ICG 001 results in decreased expression of KRT8 mRNA26191083
D007529Isoflavones"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of KRT8 protein"22248470
D007529Isoflavones[ENNG co-treated with Isoflavones] results in increased expression of KRT8 protein22248470
C544151jinfukangjinfukang results in increased expression of KRT8 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of KRT8 mRNA27081696
C068538liposomal amphotericin Bliposomal amphotericin B results in increased expression of KRT8 mRNA22863853
D017258Medroxyprogesterone AcetateAzacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]20823114
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA20823114
D019290Megestrol AcetateMegestrol Acetate results in increased expression of KRT8 protein16939895
C042720mercuric bromidemercuric bromide results in increased expression of KRT8 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of KRT8 protein20353558
D008627Mercuric ChlorideMercuric Chloride affects the expression of KRT8 protein21458406
D008701MethapyrileneMethapyrilene results in increased expression of KRT8 mRNA28935588
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of KRT8 mRNA20938992
D008727MethotrexateMethotrexate results in decreased expression of KRT8 protein24736981
D008727MethotrexateMethotrexate results in decreased expression of KRT8 mRNA21621594
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of KRT8 mRNA23179753
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of KRT8 mRNA28001369
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of KRT8 mRNA27544571
D008767Methylmercury CompoundsMethylmercury Compounds affects the expression of KRT8 protein20403756
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of KRT8 mRNA26011545
D008743Methyl Parathion[Methyl Parathion co-treated with Cadmium Chloride] results in increased expression of KRT8 mRNA22767353
D008743Methyl Parathion[Methyl Parathion co-treated with Cadmium Chloride] results in increased expression of KRT8 protein22767353
D008743Methyl ParathionMethyl Parathion results in increased expression of KRT8 mRNA22767353
D008777MethyltestosteroneMethyltestosterone results in increased expression of KRT8 mRNA29191790
D015741MetriboloneMetribolone results in increased expression of KRT8 mRNA17010196
D015741MetriboloneMetribolone results in increased expression of KRT8 protein17152098
C028577monobutyl phthalatemonobutyl phthalate affects the expression of KRT8 mRNA19162170
D009020MorphineMorphine deficiency affects the reaction [Morphine deficiency affects the reaction [Morphine results in decreased expression of KRT8 protein]]23056601
D009020MorphineMorphine deficiency affects the reaction [Morphine results in decreased expression of KRT8 protein]23056601
D009020MorphineMorphine results in decreased expression of KRT8 protein23056601
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of KRT8 protein"22001959
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of KRT8 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of KRT8 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of KRT8 mRNA"25554681
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of KRT8 mRNA15913567
D0150581-Naphthylisothiocyanate"O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of KRT8 mRNA]"15913567
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of KRT8 mRNA17522070|2538013
C051752nefazodonenefazodone results in increased expression of KRT8 mRNA24136188
C012655nimesulidenimesulide results in increased expression of KRT8 mRNA24136188
C002741N-nitrosomorpholineN-nitrosomorpholine affects the expression of KRT8 protein19716841
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA]"18778698
D009761NystatinNystatin results in increased expression of KRT8 mRNA22863853
C107010O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate"O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of KRT8 mRNA]"15913567
D009853OmeprazoleOmeprazole affects the expression of KRT8 mRNA19483382
C016340o,p'-DDT"o,p'-DDT results in increased expression of KRT8 mRNA"24096037
C016340o,p'-DDT"o,p'-DDT results in increased expression of KRT8 mRNA"24096037
D009966OrphenadrineOrphenadrine affects the expression of KRT8 mRNA23665939
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of KRT8 mRNA26272509
D052638Particulate Matter2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in decreased expression of KRT8 mRNA]28655636
D052638Particulate MatterParticulate Matter results in decreased expression of KRT8 mRNA28655636
D010416PentachlorophenolPentachlorophenol results in increased expression of KRT8 mRNA23892564
C522391perfluorododecanoic acidperfluorododecanoic acid results in increased expression of KRT8 protein26168851
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of KRT8 protein26178269
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of KRT8 mRNA19162173
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of KRT8 mRNA17097637
D010634PhenobarbitalPhenobarbital affects the expression of KRT8 mRNA19159669
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of KRT8 mRNA]19482888
D010634PhenobarbitalPhenobarbital results in increased expression of KRT8 mRNA19482888
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of and results in increased phosphorylation of KRT8 protein19409407
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KRT8 mRNA19409407
D010634Phenobarbital[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein20935162
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of KRT8 mRNA26272509
D010705PhosgenePhosgene affects the expression of KRT8 mRNA16300373
D010795Phthalic AcidsPhthalic Acids results in increased expression of KRT8 mRNA15728792
D010882Piperonyl Butoxide[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT8 protein20101389
C006253pirinixic acidpirinixic acid results in increased expression of KRT8 mRNA16221962|2005976
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in increased expression of KRT8 mRNA]20059764
C006253pirinixic acidpirinixic acid affects the expression of KRT8 mRNA19483382
D011239PrednisolonePrednisolone results in increased expression of KRT8 mRNA21621594
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of KRT8 mRNA19162173
D011374ProgesteroneProgesterone results in decreased expression of KRT8 mRNA23018184
D011374ProgesteroneProgesterone results in decreased expression of KRT8 mRNA21540246
C045950propiconazolepropiconazole results in increased expression of KRT8 mRNA21278054
D011441PropylthiouracilPropylthiouracil affects the expression of KRT8 mRNA19483382
D011794QuercetinQuercetin results in decreased expression of KRT8 protein15748282
D011794QuercetinQuercetin results in increased expression of KRT8 protein14750173
D011794QuercetinQuercetin results in decreased expression of KRT8 mRNA17103110
C541923sandostatinLARsandostatinLAR results in increased expression of KRT8 mRNA17210224
C093642SB 203580SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein]22960429
D012643SeleniumSelenium results in increased expression of KRT8 mRNA19244175
C078903seocalcitolseocalcitol results in decreased expression of KRT8 mRNA12040012
D012822Silicon DioxideSilicon Dioxide analog affects the secretion of KRT8 protein25895662
D012906SmokeSmoke results in increased metabolism of KRT8 protein20015449
D012906SmokeSmoke affects the expression of KRT8 mRNA23693141
C009277sodium arsenatesodium arsenate results in increased expression of KRT8 mRNA16882884
C017947sodium arsenitesodium arsenite results in decreased expression of KRT8 mRNA12634122
C017947sodium arsenitesodium arsenite results in increased expression of KRT8 mRNA12016162|1952463
C017947sodium arsenitesodium arsenite results in increased expression of KRT8 protein19524636
C017947sodium arsenitesodium arsenite affects the expression of KRT8 mRNA16507464
C017947sodium arsenite[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 mRNA16368122
C017947sodium arsenite[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 protein16368122
C017947sodium arsenitesodium arsenite results in increased expression of KRT8 mRNA14691202|1527641
C017947sodium arsenitesodium arsenite results in increased expression of KRT8 protein16507464
C017947sodium arseniteBenzo(a)pyrene promotes the reaction [sodium arsenite results in decreased expression of KRT8 protein]16456883
C017947sodium arsenitesodium arsenite promotes the reaction [Benzo(a)pyrene results in decreased expression of KRT8 protein]16456883
C017947sodium arsenitesodium arsenite results in decreased expression of KRT8 protein16456883
C016104sodium bichromatesodium bichromate results in increased expression of KRT8 mRNA25993096
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in decreased expression of KRT8 mRNA21621594
D012969Sodium FluorideSodium Fluoride results in decreased expression of KRT8 mRNA27862939
D012969Sodium FluorideSodium Fluoride results in decreased expression of KRT8 protein27548804
D053260SootSoot results in increased expression of KRT8 mRNA26551751
C416927SU 6656SU 6656 results in increased expression of KRT8 protein23527294
D013605T-2 ToxinT-2 Toxin affects the expression of KRT8 protein26141394
D013629TamoxifenTamoxifen results in increased expression of KRT8 mRNA19400957
D013629TamoxifenTamoxifen results in increased expression of KRT8 mRNA19400957
C047246temozolomideKRT8 mRNA affects the susceptibility to temozolomide16365179
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of KRT8 mRNA17884332
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of KRT8 mRNA12215675|2157046
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRT8 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of KRT8 mRNA17035482
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of KRT8 mRNA21602191
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of KRT8 mRNA21724226
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of KRT8 mRNA20959002
D013752TetracyclineTetracycline results in increased expression of KRT8 mRNA17522070
D013755Tetradecanoylphorbol Acetate[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 mRNA16368122
D013755Tetradecanoylphorbol Acetate[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 protein16368122
D019284ThapsigarginThapsigargin results in decreased expression of KRT8 protein21692457
D013806TheophyllineTheophylline results in increased expression of KRT8 mRNA17522070
D013853ThioacetamideThioacetamide results in increased expression of and results in increased phosphorylation of KRT8 protein18395095
D013853ThioacetamideThioacetamide results in increased expression of KRT8 mRNA18395095
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of KRT8 mRNA28943392
D013853ThioacetamideThioacetamide affects the expression of KRT8 mRNA19483382
D013853ThioacetamideThioacetamide results in increased expression of KRT8 mRNA23411599
D013893ThiramThiram results in decreased expression of KRT8 mRNA20530235
C009495titanium dioxidetitanium dioxide results in decreased expression of KRT8 mRNA23557971
C009495titanium dioxidetitanium dioxide results in increased expression of KRT8 mRNA23409001|2776080
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of KRT8 protein27189315
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of KRT8 protein27319396
D014212TretinoinTretinoin results in decreased expression of KRT8 mRNA20530235
D014212TretinoinTretinoin results in increased expression of KRT8 mRNA17034753|2193413
D014212TretinoinTretinoin results in increased expression of KRT8 protein17387344
D014212TretinoinTretinoin results in increased expression of KRT8 mRNA16236135|7201471
D014212TretinoinTretinoin results in increased expression of KRT8 protein7201471
D014212TretinoinTretinoin results in decreased expression of KRT8 mRNA24977338
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
C012589trichostatin Atrichostatin A affects the expression of KRT8 protein19294695
C012589trichostatin A[trichostatin A co-treated with decitabine] results in decreased expression of KRT8 protein19294695
C012589trichostatin Atrichostatin A results in increased expression of KRT8 mRNA24935251|2627250
C057693troglitazonetroglitazone results in decreased expression of KRT8 mRNA19140230
C113580U 0126U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein]22960429
C113580U 0126U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]15939799
C406224valdecoxibvaldecoxib results in increased expression of KRT8 mRNA24136188
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT8 mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of KRT8 mRNA23179753|2352703
D014635Valproic AcidValproic Acid results in increased expression of KRT8 mRNA19136453
D014640VancomycinVancomycin results in decreased expression of KRT8 mRNA18930951
D001335Vehicle Emissions2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in decreased expression of KRT8 mRNA]28655636
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of KRT8 mRNA28655636
C025643vinclozolinvinclozolin affects the expression of KRT8 mRNA19015723
D014801Vitamin AVitamin A results in increased expression of KRT8 mRNA17034753
D002762CholecalciferolCholecalciferol results in decreased expression of KRT8 mRNA16508948
D024483Vitamin K 3Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]15939799
D024483Vitamin K 3U 0126 inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]15939799
D024483Vitamin K 3Vitamin K 3 results in increased phosphorylation of KRT8 protein15939799
D015032ZincZinc deficiency results in increased expression of KRT8 mRNA20857495
C088658zoledronic acidzoledronic acid results in decreased expression of KRT8 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005198structural molecule activity-IEA-  
GO:0005515protein binding-IPI10852826  10954706  11581269  11684708  12577067  14756564  
15671067  15731013  15846844  16608857  19188445  20936779  
21149639  21988832  22038833  22458338  25416956  26769854  
GO:0044877protein-containing complex binding-IEA-  
GO:0097110scaffold protein binding-IPI10852826  
GO ID GO Term Qualifier Evidence PubMed
GO:0016032viral process-IEA-  
GO:0031424keratinization-TAS-  
GO:0033209tumor necrosis factor-mediated signaling pathway-IEA-  
GO:0045214sarcomere organization-IEA-  
GO:0051599response to hydrostatic pressure-IEA-  
GO:0051707response to other organism-IEA-  
GO:0060706cell differentiation involved in embryonic placenta development-IEA-  
GO:0070268cornification-TAS-  
GO:0097191extrinsic apoptotic signaling pathway-IEA-  
GO:0097284hepatocyte apoptotic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-HDA21630459  
GO:0005654nucleoplasm-IEA-  
GO:0005737cytoplasm-IDA15846844  19188445  
GO:0005829cytosol-TAS-  
GO:0005882intermediate filament-IDA10852826  
GO:0005911cell-cell junction-IEA-  
GO:0016010dystrophin-associated glycoprotein complex-IEA-  
GO:0016327apicolateral plasma membrane-IEA-  
GO:0016363nuclear matrix-IEA-  
GO:0030018Z disc-IEA-  
GO:0042383sarcolemma-IEA-  
GO:0043034costamere-IEA-  
GO:0045095keratin filament-IEA-  
GO:0045111intermediate filament cytoskeleton-IDA-  
GO:0070062extracellular exosome-HDA19199708  23533145  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1266738Developmental BiologyTAS
R-HSA-6805567KeratinizationTAS
R-HSA-6809371Formation of the cornified envelopeTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27189315The human placental proteome is affected by maternal smoking. (2016 Aug)Huuskonen PReprod Toxicol