Gene: ILDR2

387597
C1orf32|dJ782G3.1
immunoglobulin like domain containing receptor 2
protein-coding
1q24.1
Ensembl:ENSG00000143195 Vega:OTTHUMG00000034320 UniprotKB:Q71H61
NC_000001.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.970e-1 (AD)  4.054e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1053407chr1:166913500 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
BCL90.763
EFR3B0.757
SPRED20.756
LRP80.748
ABHD20.742
ZNF1540.737
ZNF6290.737
OSBPL30.735
HOMER20.733
IPO90.733

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.489
OR4F29-0.415
TGFB3-0.363
ANXA13-0.344
CTNNA3-0.342
NPIPB6-0.332
KIF19-0.331
MYOT-0.328
TRPV5-0.323
SH2D1A-0.316

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in decreased expression of ILDR2 mRNA28329830
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of ILDR2 mRNA]"19467301
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of ILDR2 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of ILDR2 mRNA19770486
D001280AtrazineAtrazine results in increased expression of ILDR2 mRNA22378314
C547126AZM551248AZM551248 results in decreased expression of ILDR2 mRNA22323515
C006780bisphenol Abisphenol A results in decreased expression of ILDR2 mRNA25181051
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of ILDR2 mRNA25993096
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of ILDR2 mRNA17484886
C018021cobaltous chloridecobaltous chloride results in decreased expression of ILDR2 mRNA24386269
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of ILDR2 mRNA23640034
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of ILDR2 mRNA21266533
D002945CisplatinCisplatin results in increased expression of ILDR2 mRNA27392435
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of ILDR2 mRNA]"19467301
D004041Dietary FatsDietary Fats results in increased expression of ILDR2 mRNA19467301
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of ILDR2 mRNA28085963
D004237DiuronDiuron results in decreased expression of ILDR2 mRNA25152437
C118739entinostatentinostat results in decreased expression of ILDR2 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
D000431EthanolEthanol results in increased expression of ILDR2 mRNA19167417
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in decreased expression of ILDR2 mRNA28329830
D017313FenretinideFenretinide results in decreased expression of ILDR2 mRNA28973697
D017313FenretinideFenretinide results in increased expression of ILDR2 mRNA28973697
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ILDR2 mRNA25613284
C045463leflunomideleflunomide results in decreased expression of ILDR2 mRNA19751817
D008727MethotrexateMethotrexate results in increased expression of ILDR2 mRNA24449571
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ILDR2 mRNA23649840
C029938nickel sulfatenickel sulfate results in decreased expression of ILDR2 mRNA22714537
D010426Pentosan Sulfuric PolyesterPentosan Sulfuric Polyester results in increased expression of ILDR2 mRNA28973697
D010634PhenobarbitalPhenobarbital affects the expression of ILDR2 mRNA23091169
C006253pirinixic acidpirinixic acid results in decreased expression of ILDR2 mRNA23811191
D010936Plant ExtractsPlant Extracts results in decreased expression of ILDR2 mRNA23557933
C017947sodium arsenitesodium arsenite results in decreased expression of ILDR2 mRNA22714537
C016104sodium bichromatesodium bichromate results in decreased expression of ILDR2 mRNA25993096
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ILDR2 mRNA26377647
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ILDR2 mRNA21889950|2629044
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ILDR2 mRNA25613284
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of ILDR2 mRNA26272509
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ILDR2 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of ILDR2 mRNA24383497|2627250
D014635Valproic AcidValproic Acid results in increased expression of ILDR2 mRNA23179753
D014635Valproic AcidValproic Acid results in increased methylation of ILDR2 gene29154799
D014635Valproic AcidValproic Acid affects the expression of ILDR2 mRNA17963808
D014750VincristineVincristine results in decreased expression of ILDR2 mRNA23649840

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0009749response to glucose-IEA-  
GO:0030073insulin secretion-IEA-  
GO:0030154cell differentiation-IEA-  
GO:0031016pancreas development-IEA-  
GO:0048873homeostasis of number of cells within a tissue-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005789endoplasmic reticulum membrane-IEA-  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal