Gene: CC2D2B

387707
C10orf130|C10orf131
coiled-coil and C2 domain containing 2B
protein-coding
10q24.1
Ensembl:ENSG00000188649 Vega:OTTHUMG00000191767 UniprotKB:Q6DHV5
NC_000010.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.865e-3 (AD)  8.183e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2039617chr10:95999446 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CLEC2D0.688
CD720.68
CD1090.657
TP53INP10.636
FAM111A0.631
RBMS30.628
ARSD0.621
USP530.617
NFATC40.608
PDGFRB0.605

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KCNG1-0.46
HAS1-0.442
SHH-0.418
MUM1L1-0.416
KLRG1-0.411
CHAC1-0.408
BEND4-0.405
NHLH1-0.4
ACHE-0.393
FAM155B-0.387

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0326424-aminophenylarsenoxide4-aminophenylarsenoxide binds to CC2D2B protein26598702
C0326424-aminophenylarsenoxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CC2D2B protein]26598702
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of CC2D2B mRNA24449571
C006632arsenic trioxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to CC2D2B protein]26598702
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of CC2D2B mRNA27188386
C005556propionaldehydepropionaldehyde results in decreased expression of CC2D2B mRNA26079696
D013849ThimerosalThimerosal results in decreased expression of CC2D2B mRNA27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal