Gene: ZNF324B

388569
-
zinc finger protein 324B
protein-coding
19q13.43
Ensembl:ENSG00000249471 Vega:OTTHUMG00000183539 UniprotKB:Q6AW86
NC_000019.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.471e-1 (AD)  6.716e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DEPDC50.911
PCDHGC50.911
TMEM2410.908
TMEM178B0.906
POLR3A0.902
LHFPL40.902
GPRASP10.901
NICN10.899
KALRN0.899
DLG30.899

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RAB13-0.56
HEY2-0.548
YES1-0.542
MYL3-0.535
ROM1-0.535
AKR1C3-0.526
GNG11-0.518
HEBP2-0.516
COPZ2-0.511
CSAG1-0.505

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D001151ArsenicArsenic affects the methylation of ZNF324B gene25304211
D002117CalcitriolCalcitriol results in decreased expression of ZNF324B mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of ZNF324B mRNA21592394
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of ZNF324B mRNA21592394
D013739TestosteroneTestosterone results in decreased expression of ZNF324B mRNA21592394
D014520UrethaneUrethane results in decreased expression of ZNF324B mRNA28818685
D014635Valproic AcidValproic Acid results in increased methylation of ZNF324B gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29212247A six-mRNA signature model for the prognosis of head and neck squamous cell carcinoma. (2017 Nov 7)Guo WOncotarget