Gene: EFCAB8

388795
-
EF-hand calcium binding domain 8
protein-coding
20q11.21
Ensembl:ENSG00000215529 Vega:OTTHUMG00000153693 UniprotKB:A8MWE9
NC_000020.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs11697967chr20:32923896 (GRCh38.p7)A>C / A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GPR310.468
C17orf470.455
POU5F1B0.448
ADAMDEC10.443
LIPN0.441
C7orf650.436
PTGER10.428
CD300E0.424
RIN30.416
SPATC10.415

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MYL1-0.256
MYH1-0.236
MYH2-0.225
TNNI1-0.206
TNNT3-0.205
AMPD1-0.204
CSN1S1-0.2
MYLPF-0.197
MAGEA4-0.186
VIT-0.183

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D001151ArsenicArsenic affects the methylation of EFCAB8 gene25304211
C006780bisphenol Abisphenol A results in decreased expression of EFCAB8 mRNA23798566
C006780bisphenol Abisphenol A results in decreased expression of EFCAB8 mRNA25181051
D011794QuercetinQuercetin results in increased expression of EFCAB8 mRNA21632981
C031389resorcinolresorcinol results in increased expression of EFCAB8 mRNA22623647

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005509calcium ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal