Gene: RND3

390
ARHE|Rho8|RhoE|memB
Rho family GTPase 3
protein-coding
2q23.3
Ensembl:ENSG00000115963 MIM:602924 Vega:OTTHUMG00000131859 UniprotKB:P61587
NC_000002.12
PubMed
0   ANCO-SNPs
ND|AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.145e-1 (AD)  7.411e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NKIRAS20.627
RGS160.62
ODC10.616
UGDH0.611
SPRY20.611
PNO10.61
TXNRD10.606
HSPD10.602
STK400.591
TRIB10.59

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.369
OR4F29-0.343
NEUROG3-0.244
TNFRSF13B-0.218
TP53TG5-0.211
SFTPC-0.208
SLC5A11-0.207
IFNA6-0.203
PRCD-0.201
CTNNA3-0.2

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB04137Guanosine-5'-TriphosphateSmall Molecule86-01-1ExperimentalTarget
ID Drug Name Action PubMed
C5768821-(2-trifluoromethoxyphenyl)-2-nitroethanone1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in decreased expression of RND3 mRNA25596134
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of RND3 mRNA28329830
C0512461-methylanthraceneSB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of RND3 mRNA]28329830
C0326681-nitropyrene1-nitropyrene results in increased expression of RND3 mRNA19041380
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of RND3 mRNA"21346803
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RND3 mRNA"15215175
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of RND3 mRNA"18648102
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in increased expression of RND3 mRNA"25912373
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide affects the expression of RND3 mRNA20829426
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of RND3 mRNA25596134
D000082AcetaminophenAcetaminophen results in increased expression of RND3 mRNA21420995|2669055
D000082AcetaminophenAcetaminophen affects the expression of RND3 mRNA17562736
D020106AcrylamideAcrylamide results in decreased expression of RND3 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 affects the expression of RND3 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of RND3 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of RND3 mRNA21641981|2715375
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of RND3 mRNA19770486
C006632arsenic trioxidearsenic trioxide results in decreased expression of RND3 mRNA26238599
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of RND3 mRNA"25757056
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of RND3 mRNA"18687144
D001280AtrazineAtrazine results in decreased expression of RND3 mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of RND3 mRNA22316170
D001564Benzo(a)pyreneAHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of RND3 mRNA]15034205
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of RND3 mRNA22342234
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of RND3 mRNA15034205|2156981
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of RND3 mRNA19770486|2222880
D004958EstradiolEGF protein inhibits the reaction [Estradiol results in decreased expression of RND3 mRNA]24758408
D004958EstradiolEstradiol results in decreased expression of RND3 mRNA24758408
D004958EstradiolEstradiol results in increased expression of RND3 mRNA21185374
C006780bisphenol Abisphenol A results in decreased expression of RND3 mRNA20678512
C006780bisphenol Abisphenol A results in increased expression of RND3 mRNA27685785|2927551
C006780bisphenol Abisphenol A results in decreased expression of RND3 mRNA26063408
C006780bisphenol Abisphenol A results in increased expression of RND3 mRNA25181051
D000069286Bortezomib[BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased expression of RND3 mRNA25522274
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of RND3 mRNA15336504
C018475butyraldehydebutyraldehyde results in increased expression of RND3 mRNA26079696
D002104CadmiumCadmium results in increased expression of RND3 mRNA21120746|2117241
D019256Cadmium ChlorideCadmium Chloride results in increased expression of RND3 mRNA25596134|2647268
D002220CarbamazepineCarbamazepine affects the expression of RND3 mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of RND3 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of RND3 mRNA27339419
C495817CC-8490CC-8490 results in increased expression of RND3 mRNA15604281
D002703ChloranilChloranil results in increased expression of RND3 mRNA24214992
C004656chloroacetaldehydechloroacetaldehyde affects the expression of RND3 mRNA25596134
C100187chloropicrinchloropicrin results in increased expression of RND3 mRNA26352163
D002737ChloropreneChloroprene results in decreased expression of RND3 mRNA23125180
D002746ChlorpromazineChlorpromazine results in decreased expression of RND3 mRNA25596134
C059262cidofovircidofovir affects the expression of RND3 mRNA25596134
D002922CiguatoxinsCiguatoxins affects the expression of RND3 mRNA18353800
D004002Clodronic AcidClodronic Acid affects the expression of RND3 mRNA25596134
C018021cobaltous chloridecobaltous chloride results in increased expression of RND3 mRNA19376846
D003042CocaineCocaine results in increased expression of RND3 mRNA17196187
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of RND3 mRNA20971185
D003375CoumestrolCoumestrol results in decreased expression of RND3 mRNA19167446
C029892cupric chloridecupric chloride results in increased expression of RND3 mRNA24650576
D016572CyclosporineCyclosporine results in decreased expression of RND3 mRNA27989131
D016572CyclosporineCyclosporine results in increased expression of RND3 mRNA20106945|2559613
D016572CyclosporineCyclosporine results in increased methylation of RND3 promoter27989131
D016572CyclosporineCyclosporine results in decreased expression of RND3 mRNA25596134
C089595cylindrospermopsincylindrospermopsin results in increased expression of RND3 mRNA24921660
C093628cyproconazolecyproconazole results in decreased expression of RND3 mRNA26238599
D003976DiazinonDiazinon affects the expression of RND3 mRNA22546817
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of RND3 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of RND3 mRNA21266533
D002945CisplatinCisplatin results in increased expression of RND3 protein15340047
D004026DieldrinDieldrin affects the expression of RND3 mRNA22546817
D004041Dietary FatsDietary Fats affects the expression of RND3 mRNA19680557
D004041Dietary FatsDietary Fats results in increased expression of RND3 mRNA18042831
D004041Dietary FatsDietary Fats results in decreased expression of RND3 mRNA21852083
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of RND3 mRNA25242112
D004178DiquatDiquat results in increased expression of RND3 mRNA21172416
C024565ethylene dichlorideethylene dichloride results in increased expression of RND3 mRNA28189721
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of RND3 mRNA23649840
D011345FenofibrateFenofibrate results in decreased expression of RND3 mRNA25596134
D005411Flame RetardantsFlame Retardants results in increased expression of RND3 mRNA27219277
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of RND3 mRNA28329830
C007738fluorantheneSB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of RND3 mRNA]28329830
D005557FormaldehydeFormaldehyde results in increased expression of RND3 mRNA23416264|2364984
C004312glycidolglycidol results in decreased expression of RND3 mRNA24915197
D055768Halogenated Diphenyl EthersHalogenated Diphenyl Ethers results in increased expression of RND3 mRNA27219277
C492448ICG 001ICG 001 results in increased expression of RND3 mRNA26191083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of RND3 mRNA25613284
C098607JP8 aviation fuelJP8 aviation fuel results in decreased expression of RND3 mRNA16835149
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of RND3 mRNA24435446
D007649KetamineKetamine results in decreased expression of RND3 mRNA20080153
D007854LeadLead affects the expression of RND3 mRNA28903495
C482199lipopolysaccharide, E coli O55-B5"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of RND3 mRNA"18930950
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of RND3 mRNA25613284
D018021Lithium ChlorideLithium Chloride results in increased expression of RND3 mRNA15711924
C042720mercuric bromidemercuric bromide results in increased expression of RND3 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
D008627Mercuric ChlorideMercuric Chloride results in increased expression of RND3 mRNA16507785
D008687MetforminMetformin affects the expression of RND3 mRNA25596134
D008727MethotrexateMethotrexate results in increased expression of RND3 mRNA24657277
D008748MethylcholanthreneMethylcholanthrene results in decreased expression of RND3 mRNA20713471
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of RND3 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of RND3 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of RND3 mRNA"17196187
D018817N-Methyl-3,4-methylenedioxyamphetamine"SL 327 inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of RND3 mRNA]"17196187
C008493methylselenic acidmethylselenic acid results in increased expression of RND3 mRNA18548127
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of RND3 mRNA16809437
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of RND3 protein24625837
D009151Mustard GasMustard Gas results in increased expression of RND3 mRNA25102026
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of RND3 mRNA"25102311
C022838nickel chloridenickel chloride affects the expression of RND3 mRNA22546817
D009538NicotineNicotine results in increased splicing of RND3 mRNA alternative form23825647
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of RND3 mRNA17616710
C570897NSC668394NSC668394 results in increased expression of RND3 mRNA27137931
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of RND3 mRNA20971185
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of RND3 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of RND3 mRNA25729387
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of RND3 mRNA17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of RND3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of RND3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of RND3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of RND3 mRNA]17655762
D010100OxygenOxygen deficiency results in increased expression of RND3 mRNA25596134
D010100OxygenOxygen deficiency results in increased expression of RND3 mRNA24205000
D000073878Palm OilPalm Oil affects the expression of RND3 mRNA19680557
D000073878Palm OilPalm Oil results in increased expression of RND3 mRNA18042831
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of RND3 mRNA26272509
D052638Particulate Matteroxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of RND3 mRNA]17655762
D052638Particulate MatterParticulate Matter affects the expression of RND3 mRNA17655762
D052638Particulate MatterParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of RND3 mRNA]17655762
C410127PCB 180PCB 180 results in decreased expression of RND3 mRNA26238599
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of RND3 mRNA18593933
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of RND3 mRNA19095052
D010426Pentosan Sulfuric PolyesterPentosan Sulfuric Polyester results in increased expression of RND3 mRNA28973697
D010634PhenobarbitalPhenobarbital affects the expression of RND3 mRNA19159669
D010634PhenobarbitalPhenobarbital results in increased expression of RND3 mRNA19270015
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of RND3 mRNA26272509
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of RND3 mRNA19710929
C006253pirinixic acidpirinixic acid results in decreased expression of RND3 mRNA18445702
D010894PiroxicamPiroxicam results in increased expression of RND3 mRNA21858171
D010938Plant OilsPlant Oils results in increased expression of RND3 mRNA23370395
D011374ProgesteroneProgesterone results in increased expression of RND3 mRNA21540246
D011441PropylthiouracilPropylthiouracil results in increased expression of RND3 mRNA24780913
C005266quinomethionatequinomethionate affects the expression of RND3 mRNA15387888
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in decreased expression of RND3 mRNA16497877
D015474IsotretinoinIsotretinoin results in decreased expression of RND3 mRNA20436886
C089730rosiglitazonerosiglitazone results in decreased expression of RND3 mRNA25596134
C093642SB 203580SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of RND3 mRNA]28329830
D012643SeleniumSelenium results in decreased expression of RND3 mRNA19244175
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of RND3 mRNA25895662
C424127SL 327"SL 327 inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of RND3 mRNA]"17196187
C017947sodium arsenitesodium arsenite affects the methylation of RND3 gene28589171
C017947sodium arsenitesodium arsenite results in decreased expression of RND3 mRNA28595984
C017947sodium arsenitesodium arsenite results in increased expression of RND3 mRNA10910055
D012999SomanSoman results in increased expression of RND3 mRNA19281266
C013698tallowtallow affects the expression of RND3 mRNA19680557
D013629TamoxifenTamoxifen results in increased expression of RND3 mRNA15604281
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of RND3 mRNA20106945|2163298
D013749TetrachlorodibenzodioxinAHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RND3 mRNA]15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of RND3 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of RND3 mRNA18691609
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of RND3 mRNA15034205
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of RND3 mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of RND3 mRNA28065790
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of RND3 mRNA18087596
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of RND3 mRNA25729387
D019772TopotecanTopotecan results in increased expression of RND3 mRNA25729387
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of RND3 mRNA24935251|2627250
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of RND3 mRNA"26179874
C057693troglitazonetroglitazone results in decreased expression of RND3 mRNA25596134
C080163trovafloxacin"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of RND3 mRNA"18930950
D014415TunicamycinTunicamycin results in decreased expression of RND3 mRNA22378314
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased methylation of RND3 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of RND3 mRNA23179753|2438349
D001335Vehicle Emissionsoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of RND3 mRNA]17655762
D001335Vehicle EmissionsVehicle Emissions affects the expression of RND3 mRNA17655762
D001335Vehicle EmissionsVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of RND3 mRNA]17655762
C025643vinclozolinvinclozolin affects the expression of RND3 mRNA19015723
C029297vinylidene chloridevinylidene chloride results in increased expression of RND3 mRNA26682919
D014810Vitamin EVitamin E results in decreased expression of RND3 mRNA19244175
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RND3 mRNA"27188386
C111237vorinostatvorinostat results in decreased expression of RND3 mRNA26238599
C111237vorinostatvorinostat results in increased expression of RND3 mRNA26272509
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of RND3 mRNA18593933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003924GTPase activity-IBA21873635  
GO:0003924GTPase activity-IEA-  
GO:0005515protein binding-IPI23622247  
GO:0005525GTP binding-IBA21873635  
GO:0005525GTP binding-IEA-  
GO:0019901protein kinase binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0007015actin filament organization-IBA21873635  
GO:0007155cell adhesion-TAS9531558  
GO:0007163establishment or maintenance of cell polarity-IBA21873635  
GO:0007264small GTPase mediated signal transduction-IEA-  
GO:0007266Rho protein signal transduction-IBA21873635  
GO:0008360regulation of cell shape-IBA21873635  
GO:0030036actin cytoskeleton organization-TAS9531558  
GO:0030334regulation of cell migration-IBA21873635  
GO:0030950establishment or maintenance of actin cytoskeleton polarity-IBA21873635  
GO:0032956regulation of actin cytoskeleton organization-IBA21873635  
GO:0051017actin filament bundle assembly-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0000139Golgi membrane-IEA-  
GO:0005737cytoplasm-IBA21873635  
GO:0005886plasma membraneCOLOCALIZES_WITHIBA21873635  
GO:0005925focal adhesion-HDA21423176  
GO:0005938cell cortex-IBA21873635  
GO:0031410cytoplasmic vesicle-IBA21873635  
GO:0032153cell division site-IBA21873635  
GO:0043231intracellular membrane-bounded organelle-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29551738Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. (2018 Mar 15)Dong JClin Gastroenterol Hepatol