Gene: LAMC2

3918
B2T|BM600|CSF|EBR2|EBR2A|LAMB2T|LAMNB2
laminin subunit gamma 2
protein-coding
1q25.3
Ensembl:ENSG00000058085 MIM:150292 Vega:OTTHUMG00000035520 UniprotKB:Q13753
NG_007079.2
SNP Mapped
1   ANCO-SNPs
AD
0   
5.946e-1 (AD)  5.096e-1 (ND)   (Frontal_Cortex)
6.020e-1 (AD)  8.629e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs16860582chr1:183221316 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SAG0.879
GPR1010.876
DRD30.863
ENTHD10.861
GPR10.861
DGKK0.856
PRLR0.856
AMBN0.855
TMPRSS60.853
OTOF0.844

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ALDH1A1-0.374
SLC17A7-0.341
NXPH3-0.326
NTNG2-0.32
NEUROD2-0.299
SOHLH1-0.298
RNF182-0.282
GALNT9-0.277
SYTL2-0.268
NANOS3-0.267

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0252051,10-phenanthroline"1,10-phenanthroline inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]"18095945
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of LAMC2 mRNA"28903501
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of LAMC2 mRNA"25710175
C0352082-amino-4,6-dinitrotoluene"2-amino-4,6-dinitrotoluene results in increased expression of LAMC2 protein"26251320
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C0036144-toluenesulfonyl fluoride4-toluenesulfonyl fluoride inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]18095945
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of LAMC2 mRNA17562736
D020106AcrylamideAcrylamide results in increased expression of LAMC2 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of LAMC2 mRNA22100608
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of LAMC2 protein21527772
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of LAMC2 mRNA23630614
D000393Air PollutantsAir Pollutants analog results in increased expression of LAMC2 mRNA21757418
D000447AldehydesAldehydes results in increased expression of LAMC2 mRNA25014914
D000643Ammonium ChlorideAmmonium Chloride affects the expression of LAMC2 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of LAMC2 mRNA"22863853
C006632arsenic trioxideLAMC2 protein results in decreased susceptibility to arsenic trioxide20707922
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of LAMC2 mRNA"23917077
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of LAMC2 mRNA27195522
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of LAMC2 mRNA22610609
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of LAMC2 mRNA20660070
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of LAMC2 mRNA19619570
D004958EstradiolEstradiol results in increased expression of LAMC2 mRNA19619570
D004958EstradiolEstradiol results in increased expression of LAMC2 mRNA15289156|1948475
D004958Estradiol[bisphenol A co-treated with Estradiol] results in decreased expression of LAMC2 mRNA26496021
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of LAMC2 mRNA28628672
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in decreased expression of LAMC2 mRNA26496021
C006780bisphenol A[bisphenol A co-treated with Testosterone] results in decreased expression of LAMC2 mRNA26496021
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of LAMC2 mRNA15336504
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of LAMC2 mRNA15003993
C018475butyraldehydebutyraldehyde results in increased expression of LAMC2 mRNA26079696
C584509C646 compoundC646 compound results in increased expression of LAMC2 mRNA26191083
D019256Cadmium ChlorideCadmium Chloride results in increased expression of LAMC2 mRNA25993096
C100187chloropicrinchloropicrin results in decreased expression of LAMC2 mRNA26352163
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LAMC2 mRNA20938992
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of LAMC2 mRNA20971185
D003300CopperCopper deficiency results in increased expression of LAMC2 mRNA26033743
D003520CyclophosphamideCyclophosphamide results in increased expression of LAMC2 mRNA21527772
D016572CyclosporineCyclosporine results in decreased expression of LAMC2 mRNA22147139
D016572CyclosporineCyclosporine results in decreased expression of LAMC2 mRNA21865292
D003609DactinomycinDactinomycin results in increased expression of LAMC2 mRNA21527772
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of LAMC2 mRNA28628672
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of LAMC2 mRNA27392435
D019259Lamivudine[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNA16931933
D019259Lamivudine[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA16931933
D004041Dietary FatsDietary Fats results in decreased expression of LAMC2 mRNA18042831|2501614
D019422Dietary SucroseDietary Sucrose results in increased expression of LAMC2 mRNA26033743
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate affects the expression of LAMC2 mRNA27405655
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of LAMC2 mRNA27405655
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of LAMC2 mRNA21527772
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of LAMC2 mRNA22129741
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of LAMC2 mRNA15289156
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of LAMC2 mRNA"21527772
D004237DiuronDiuron results in decreased expression of LAMC2 mRNA21551480
D004317Doxorubicin[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of LAMC2 mRNA21040762
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of LAMC2 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of LAMC2 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LAMC2 mRNA17942748
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of LAMC2 intron27776689
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LAMC2 mRNA20938992
D005557FormaldehydeFormaldehyde results in increased expression of LAMC2 mRNA27664576
C069837fullerene C60fullerene C60 results in increased expression of LAMC2 mRNA19167457
C039281furanfuran results in increased expression of LAMC2 mRNA27387713
D019833GenisteinGenistein results in decreased expression of LAMC2 mRNA14871586
D019833GenisteinGenistein results in increased expression of LAMC2 mRNA15289156
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of LAMC2 mRNA20044591
C492448ICG 001ICG 001 results in increased expression of LAMC2 mRNA26191083
D019469Indinavir[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNA16931933
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of LAMC2 mRNA22129741
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of LAMC2 mRNA28628672
D007501IronIron deficiency results in increased expression of LAMC2 mRNA16629162
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of LAMC2 mRNA28628672
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of LAMC2 mRNA27392435
C544151jinfukangjinfukang results in increased expression of LAMC2 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of LAMC2 mRNA27432991
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of LAMC2 mRNA12057914
C059451lornoxicamlornoxicam results in increased expression of LAMC2 mRNA23142791
C032881lysophosphatidic acidlysophosphatidic acid results in increased expression of LAMC2 mRNA15541073
D008244LysophosphatidylcholinesLysophosphatidylcholines results in increased expression of LAMC2 mRNA15541073
D008344Maneb[Paraquat co-treated with Maneb] affects the expression of LAMC2 mRNA22563483
D008466MechlorethamineMechlorethamine results in decreased expression of LAMC2 protein9504665
D008466MechlorethamineMechlorethamine results in increased degradation of LAMC2 protein18095945
C042720mercuric bromidemercuric bromide results in increased expression of LAMC2 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LAMC2 mRNA20938992
D008748Methylcholanthrene[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA23519560
D015735MifepristoneMifepristone results in increased expression of LAMC2 mRNA17584828
D009151Mustard Gas"1,10-phenanthroline inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]"18095945
D009151Mustard Gas4-toluenesulfonyl fluoride inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]18095945
D009151Mustard GasMustard Gas results in decreased expression of LAMC2 protein9504665
D009151Mustard GasMustard Gas results in increased degradation of [LAMA3 protein binds to LAMB3 protein binds to LAMC2 protein]18095945
D009151Mustard GasMustard Gas results in increased degradation of LAMC2 protein18095945|1830032
D009151Mustard GasMustard Gas results in increased expression of LAMC2 mRNA19526566|2193943
D009151Mustard GasMustard Gas results in increased expression of LAMC2 protein19526566
D009151Mustard GasMustard Gas results in decreased expression of LAMC2 protein9302645
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of LAMC2 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of LAMC2 mRNA"25554681
C022838nickel chloridenickel chloride results in decreased expression of LAMC2 mRNA12839937
C029938nickel sulfatenickel sulfate results in decreased expression of LAMC2 mRNA22714537
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of LAMC2 mRNA20971185
C558013NSC 689534NSC 689534 results in increased expression of LAMC2 mRNA20971185
D019319Okadaic AcidOkadaic Acid results in increased expression of LAMC2 mRNA25270620
C500026palbociclibpalbociclib results in increased expression of LAMC2 mRNA22869556
D000073878Palm OilPalm Oil results in decreased expression of LAMC2 mRNA18042831
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of LAMC2 mRNA26272509
D010269Paraquat[Paraquat co-treated with Maneb] affects the expression of LAMC2 mRNA22563483
D010269ParaquatParaquat results in increased expression of LAMC2 mRNA22563483
C046012pentanalpentanal results in increased expression of LAMC2 mRNA26079696
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of LAMC2 mRNA23602845
D010615PhenacetinPhenacetin results in increased expression of LAMC2 mRNA23142791
D010634PhenobarbitalPhenobarbital results in decreased expression of LAMC2 mRNA25270620
D010656PhenylephrinePhenylephrine results in increased expression of LAMC2 mRNA18158353
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of LAMC2 mRNA26272509
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of LAMC2 mRNA22714537
D011192Potassium DichromatePotassium Dichromate results in increased expression of LAMC2 mRNA23608068
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of LAMC2 mRNA20660070
C005556propionaldehydepropionaldehyde results in increased expression of LAMC2 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in increased expression of LAMC2 mRNA24780913
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of LAMC2 mRNA"21152443
C428725pyridabenpyridaben results in increased expression of LAMC2 mRNA22563483
D015575RoxithromycinRoxithromycin results in decreased expression of LAMC2 protein14687228
D019258Saquinavir[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA16931933
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of LAMC2 mRNA"23917077
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of LAMC2 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in increased expression of LAMC2 mRNA25351596
D012834SilverSilver results in decreased expression of LAMC2 mRNA27131904
D020123SirolimusSirolimus results in increased expression of LAMC2 mRNA21865292
D012999SomanSoman results in increased expression of LAMC2 mRNA19281266
C060506sphingosine 1-phosphatesphingosine 1-phosphate results in increased expression of LAMC2 mRNA15541073
D016559TacrolimusTacrolimus results in increased expression of LAMC2 mRNA21865292
D013629TamoxifenTamoxifen affects the expression of LAMC2 mRNA17555576
D013739Testosterone[bisphenol A co-treated with Testosterone] results in decreased expression of LAMC2 mRNA26496021
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of LAMC2 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of LAMC2 mRNA22574217
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of LAMC2 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of LAMC2 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LAMC2 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of LAMC2 mRNA17586704
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of LAMC2 mRNA22298810
C117153tetracycline CMT-8tetracycline CMT-8 results in increased expression of LAMC2 protein11983005
D013755Tetradecanoylphorbol Acetate[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA23519560
C009495titanium dioxidetitanium dioxide results in increased expression of LAMC2 mRNA23409001|2355797
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of LAMC2 mRNA27865774
D014118Toxins, Biological"Toxins, Biological affects the expression of LAMC2 mRNA"19682533
D014212TretinoinTretinoin results in increased expression of LAMC2 mRNA17138961
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of LAMC2 mRNA24935251|2627250
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of LAMC2 mRNA19042947
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMC2 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of LAMC2 mRNA29154799
D014635Valproic AcidValproic Acid results in decreased methylation of LAMC2 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of LAMC2 mRNA23179753|2627250
D014638VanadatesVanadates results in increased expression of LAMC2 mRNA22714537
D014640VancomycinVancomycin results in decreased expression of LAMC2 mRNA18930951
C025643vinclozolinvinclozolin affects the expression of LAMC2 mRNA19015723
C025643vinclozolinvinclozolin results in decreased expression of LAMC2 mRNA23034163
D015215Zidovudine[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNA16931933
D015215Zidovudine[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA16931933
C088658zoledronic acidzoledronic acid results in increased expression of LAMC2 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0008201heparin binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007155cell adhesion-IEA-  
GO:0008284positive regulation of cell proliferation-IMP24091622  
GO:0008544epidermis development-TAS8012394  
GO:0030198extracellular matrix organization-TAS-  
GO:0030335positive regulation of cell migration-IMP24091622  
GO:0031581hemidesmosome assembly-TAS-  
GO:0048731system development-IEA-  
GO:0070831basement membrane assembly-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005607laminin-2 complex-IEA-  
GO:0005615extracellular space-IEA-  
GO:0005938cell cortex-IEA-  
GO:0016020membrane-IEA-  
GO:0048471perinuclear region of cytoplasm-IEA-  
KEGG ID KEGG Term
hsa04510Focal adhesion
hsa04512ECM-receptor interaction
hsa05145Toxoplasmosis
hsa05146Amoebiasis
hsa05200Pathways in cancer
hsa05222Small cell lung cancer
Reactome ID Reactome Term Evidence
R-HSA-1474228Degradation of the extracellular matrixTAS
R-HSA-1474228Degradation of the extracellular matrixIEA
R-HSA-1474244Extracellular matrix organizationIEA
R-HSA-1474244Extracellular matrix organizationTAS
R-HSA-1474290Collagen formationTAS
R-HSA-1500931Cell-Cell communicationTAS
R-HSA-162582Signal TransductionTAS
R-HSA-2022090Assembly of collagen fibrils and other multimeric structuresTAS
R-HSA-2214320Anchoring fibril formationTAS
R-HSA-3000157Laminin interactionsIEA
R-HSA-3000157Laminin interactionsTAS
R-HSA-3000171Non-integrin membrane-ECM interactionsIEA
R-HSA-446107Type I hemidesmosome assemblyTAS
R-HSA-446728Cell junction organizationTAS
R-HSA-6806834Signaling by METTAS
R-HSA-8874081MET activates PTK2 signalingTAS
R-HSA-8875878MET promotes cell motilityTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal