Gene: FSIP2

401024
-
fibrous sheath interacting protein 2
protein-coding
2q32.1
Ensembl:ENSG00000188738 MIM:615796 Vega:OTTHUMG00000153874 UniprotKB:Q5CZC0
NG_051365.1
PubMed
0   ANCO-SNPs
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.543e-1 (AD)  7.807e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4K30.695
OR1I10.667
OR14J10.665
OR10A70.663
ZNF990.662
OR2M70.662
POU5F20.662
MBL20.656
NPHS20.654
OR2J20.649

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DHDH-0.329
CHAC1-0.323
RHEBL1-0.31
NANOS3-0.309
MRPL46-0.309
B9D2-0.288
PSPN-0.281
GSG1-0.281
MESP1-0.279
C16orf95-0.275

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in decreased expression of FSIP2 mRNA29067470
D000082AcetaminophenAcetaminophen results in increased expression of FSIP2 mRNA26690555
C006780bisphenol Abisphenol A affects the expression of FSIP2 mRNA25181051
C117342calfactant"[Nanotubes, Carbon co-treated with calfactant] results in decreased expression of FSIP2 protein"23026733
C568376MT19c compoundMT19c compound results in increased expression of FSIP2 mRNA21781307
D037742Nanotubes, Carbon"[Nanotubes, Carbon co-treated with calfactant] results in decreased expression of FSIP2 protein"23026733
C006253pirinixic acidpirinixic acid results in increased expression of FSIP2 mRNA20813756
D012969Sodium FluorideSodium Fluoride results in increased expression of FSIP2 protein28918527
D013849ThimerosalThimerosal results in increased expression of FSIP2 mRNA27188386
D014520UrethaneUrethane results in decreased expression of FSIP2 mRNA28818685

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms. (2012 Apr)Wang KSJ Neural Transm (Vienna)