Gene: SPINK14

408187
SPINK5L2
serine peptidase inhibitor, Kazal type 14 (putative)
protein-coding
5q32
Ensembl:ENSG00000196800 Vega:OTTHUMG00000129732 UniprotKB:Q6IE38
NC_000005.10
SNP Mapped
0   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.623e-1 (AD)  6.199e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NCBP2-AS20
ZDHHC150
ZDHHC150
ZDHHC140
ZDHHC140
ZDHHC170
ZDHHC170
ZDHHC160
ZDHHC160
ZDHHC110

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NCBP2-AS20
ZDHHC150
ZDHHC150
ZDHHC140
ZDHHC140
ZDHHC170
ZDHHC170
ZDHHC160
ZDHHC160
ZDHHC110

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C006780bisphenol Abisphenol A results in decreased expression of SPINK14 mRNA25181051
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of SPINK14 mRNA26472689
D019422Dietary SucroseDietary Sucrose results in increased expression of SPINK14 mRNA26033743
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of SPINK14 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal