| C504897 | 12-(3-adamantan-1-ylureido)dodecanoic acid | 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 28694203 |
| C026486 | 1,2,5,6-dibenzanthracene | "[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of SMAD3 mRNA" | 18711122 |
| C070046 | 1,2-dioleoyloxy-3-(trimethylammonium)propane | "[Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of SMAD3 mRNA" | 22129739 |
| C072581 | 16-hydroxycleroda-3,13(14)-dien-15,16-olide | "16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased expression of SMAD3 protein" | 23628706 |
| C072581 | 16-hydroxycleroda-3,13(14)-dien-15,16-olide | "16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased expression of SMAD3 protein" | 23628706 |
| C051246 | 1-methylanthracene | [1-methylanthracene co-treated with fluoranthene] results in increased expression of SMAD3 mRNA | 28329830 |
| C082823 | 1-oleoyl lysophosphatidylcholine | SMAD3 protein results in decreased abundance of 1-oleoyl lysophosphatidylcholine | 23034213 |
| C089215 | 1-palmitoyl-2-lysophosphatidylcholine | SMAD3 protein results in decreased abundance of 1-palmitoyl-2-lysophosphatidylcholine | 23034213 |
| C581572 | 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea | 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea results in increased expression of SMAD3 mRNA | 25827057 |
| C029497 | 2,3-bis(3'-hydroxybenzyl)butyrolactone | "2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of SMAD3 mRNA" | 19167446 |
| C029497 | 2,3-bis(3'-hydroxybenzyl)butyrolactone | "[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SMAD3 mRNA" | 19167446 |
| C061282 | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | "8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of SMAD3 protein]" | 22063920 |
| C000595230 | 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one | "2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]" | 27704718 |
| C047368 | 3-methylquercetin | 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 27151496 |
| C047368 | 3-methylquercetin | NFE2L2 protein affects the reaction [3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]] | 27151496 |
| C572961 | 4-(4-(3-(4-trifluoromethoxy-phenyl)ureido)cyclohexyloxy)benzoic acid | 4-(4-(3-(4-trifluoromethoxy-phenyl)ureido)cyclohexyloxy)benzoic acid results in decreased expression of SMAD3 protein modified form | 25377915 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]" | 28871336 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [zoledronic acid results in increased phosphorylation of SMAD3 protein]" | 28871336 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]" | 21520325 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased expression of HAS2 mRNA]" | 21520325 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased expression of TNFAIP6 mRNA]" | 21520325 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] promotes the reaction [FSHB protein results in increased chemical synthesis of Progesterone]" | 21520325 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] which co-treated with FSHB protein] results in increased expression of PTX3 mRNA" | 21520325 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] which results in decreased susceptibility to FSHB protein" | 21520325 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Sodium Fluoride] results in decreased phosphorylation of SMAD3 protein" | 29127033 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Sodium Fluoride results in increased expression of SMAD3 mRNA]" | 29127033 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [TGFB3 protein affects the localization of SMAD3 protein]" | 21586554 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [TGFB3 protein affects the localization of SMAD3 protein modified form]" | 21586554 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased phosphorylation of SMAD3 protein" | 29127033 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased phosphorylation of SMAD3 protein]" | 28982980 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased phosphorylation of SMAD3 protein" | 28982980 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [EGF protein results in increased chemical synthesis of Hyaluronic Acid]" | 21520325 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] which results in decreased susceptibility to EGF protein" | 21520325 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of SMAD3 protein" | 21520325 |
| C517041 | (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) | "(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in decreased expression of SMAD3 mRNA" | 19561079 |
| C041594 | 4-nonylphenol | 4-nonylphenol results in decreased phosphorylation of SMAD3 protein | 24308608 |
| C041594 | 4-nonylphenol | fulvestrant inhibits the reaction [4-nonylphenol results in decreased phosphorylation of SMAD3 protein] | 24308608 |
| C012606 | 4-vinyl-1-cyclohexene dioxide | 4-vinyl-1-cyclohexene dioxide affects the expression of SMAD3 mRNA | 20829426 |
| C098657 | 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine | "8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide promotes the reaction [5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine binds to and results in decreased activity of SMAD3 protein]" | 22063920 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]" | 21520325 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Progesterone]" | 21520325 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] which results in decreased susceptibility to FSHB protein" | 21520325 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] which results in increased susceptibility to FSHB protein" | 21520325 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein" | 21480330 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased expression of SMAD3 protein" | 20682692 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein" | 21520325 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [EGF protein results in increased chemical synthesis of Hyaluronic Acid]" | 21520325 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] which results in decreased susceptibility to EGF protein" | 21520325 |
| C508504 | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] which results in increased susceptibility to EGF protein" | 21520325 |
| C570019 | 8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide | "8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide binds to and results in decreased activity of SMAD3 protein" | 22063920 |
| C570019 | 8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide | "8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of SMAD3 protein]" | 22063920 |
| C570019 | 8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide | "8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide inhibits the reaction [Ethanol results in increased phosphorylation of SMAD3 protein]" | 22063920 |
| C570019 | 8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide | "8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide promotes the reaction [5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine binds to and results in decreased activity of SMAD3 protein]" | 22063920 |
| C570019 | 8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide | "8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide results in decreased phosphorylation of SMAD3 protein" | 22063920 |
| D000079 | Acetaldehyde | Acetaldehyde results in increased phosphorylation of SMAD3 protein | 16025520 |
| D000079 | Acetaldehyde | SMAD3 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA] | 16025520 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of SMAD3 mRNA | 21420995 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of SMAD3 mRNA | 22230336 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of SMAD3 mRNA | 17562736 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of SMAD3 mRNA | 11752693 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 21131394 |
| C058956 | acteoside | acteoside results in increased phosphorylation of SMAD3 protein | 17634406 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased expression of SMAD3 mRNA | 21641981|2210060 |
| C412373 | AG 1879 | AG 1879 inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of SMAD3 protein] | 27519288 |
| C103303 | alitretinoin | [TO-901317 co-treated with alitretinoin] results in increased expression of SMAD3 protein | 17194744 |
| D013196 | Dihydrotestosterone | Dihydrotestosterone results in increased expression of SMAD3 mRNA | 16597033 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of SMAD3 protein] | 27519288 |
| C010845 | aluminum chloride | aluminum chloride inhibits the reaction [SMAD2 protein binds to SMAD3 protein binds to SMAD4 protein] | 26658030 |
| C010845 | aluminum chloride | aluminum chloride results in decreased expression of [SMAD2 protein binds to SMAD3 protein binds to SMAD4 protein] | 27720690 |
| C010845 | aluminum chloride | TGFB1 protein inhibits the reaction [aluminum chloride results in decreased expression of [SMAD2 protein binds to SMAD3 protein binds to SMAD4 protein]] | 27720690 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in decreased expression of SMAD3 mRNA | 24449571 |
| D001151 | Arsenic | Arsenic results in increased expression of SMAD3 protein modified form | 24348802 |
| D001151 | Arsenic | Grape Seed Extract inhibits the reaction [Arsenic results in increased expression of SMAD3 protein modified form] | 24348802 |
| C006632 | arsenic trioxide | arsenic trioxide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of SMAD3 protein] | 24762191 |
| C006632 | arsenic trioxide | arsenic trioxide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 24762191|2519664 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of SMAD3 mRNA | 25196641|2530421 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of SMAD3 protein | 25196641 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of and results in increased phosphorylation of SMAD3 protein | 21649584 |
| C006632 | arsenic trioxide | [arsenic trioxide results in increased expression of MIR491 mRNA] which results in decreased expression of SMAD3 mRNA | 25196641 |
| C006632 | arsenic trioxide | Hydrogen Peroxide inhibits the reaction [arsenic trioxide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]] | 24762191 |
| C006632 | arsenic trioxide | MIR491 affects the reaction [arsenic trioxide results in decreased expression of SMAD3 mRNA] | 25304214 |
| C006632 | arsenic trioxide | MIR491 mRNA promotes the reaction [arsenic trioxide results in decreased expression of SMAD3 mRNA] | 25196641 |
| C006632 | arsenic trioxide | SMAD3 protein promotes the reaction [arsenic trioxide results in increased expression of CDKN1A mRNA] | 21649584 |
| C006632 | arsenic trioxide | SMAD3 protein promotes the reaction [arsenic trioxide results in increased expression of CDKN1A protein] | 21649584 |
| C006632 | arsenic trioxide | SMAD3 protein results in decreased susceptibility to arsenic trioxide | 20707922 |
| C015001 | arsenite | arsenite inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein] | 26354774 |
| C015001 | arsenite | arsenite inhibits the reaction [TGFB2 protein results in increased localization of SMAD3 protein] | 25145660 |
| C015001 | arsenite | arsenite inhibits the reaction [XPO4 protein results in increased export of SMAD3 protein] | 26354774 |
| C015001 | arsenite | leptomycin B inhibits the reaction [arsenite inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]] | 26354774 |
| C015001 | arsenite | leptomycin B inhibits the reaction [arsenite inhibits the reaction [XPO4 protein results in increased export of SMAD3 protein]] | 26354774 |
| C015001 | arsenite | Zinc inhibits the reaction [arsenite inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]] | 26354774 |
| D001194 | Asbestos | "[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of and results in increased phosphorylation of SMAD3 protein" | 25358858 |
| D001194 | Asbestos | "[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of SMAD3 mRNA" | 25358858 |
| C044946 | benazepril | benazepril affects the expression of SMAD3 mRNA | 16635409 |
| C044946 | benazepril | benazepril affects the expression of SMAD3 protein | 16635409 |
| C044946 | benazepril | [benazepril co-treated with candesartan] results in decreased expression of SMAD3 protein | 19487956 |
| C044946 | benazepril | [benazepril co-treated with irbesartan] affects the expression of SMAD3 mRNA | 16635409 |
| C044946 | benazepril | [benazepril co-treated with irbesartan] affects the expression of SMAD3 protein | 16635409 |
| D001554 | Benzene | Benzene results in increased expression of SMAD3 mRNA | 19162166 |
| C006703 | benzo(b)fluoranthene | [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of SMAD3 mRNA | 18711122 |
| C047723 | benzophenone | benzophenone results in decreased phosphorylation of SMAD3 protein | 24308608 |
| C047723 | benzophenone | fulvestrant inhibits the reaction [benzophenone results in decreased phosphorylation of SMAD3 protein] | 24308608 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of SMAD3 mRNA | 22228805 |
| D001564 | Benzo(a)pyrene | "[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of SMAD3 mRNA" | 18711122 |
| D001564 | Benzo(a)pyrene | [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of SMAD3 mRNA | 18711122 |
| D001564 | Benzo(a)pyrene | "[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of SMAD3 mRNA" | 18711122 |
| D001564 | Benzo(a)pyrene | [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of SMAD3 mRNA | 18711122 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SMAD3 mRNA" | 19150397|2001819 |
| D004958 | Estradiol | EGF protein inhibits the reaction [Estradiol results in decreased expression of SMAD3 mRNA] | 24758408 |
| D004958 | Estradiol | Estradiol affects the expression of SMAD3 mRNA | 14699072|2257421 |
| D004958 | Estradiol | [Estradiol co-treated with Progesterone] results in decreased expression of SMAD3 mRNA | 20660070 |
| D004958 | Estradiol | Estradiol results in decreased expression of SMAD3 mRNA | 19167446|2475840 |
| D004958 | Estradiol | Estradiol results in decreased phosphorylation of SMAD3 protein | 24308608|2640794 |
| D004958 | Estradiol | fulvestrant inhibits the reaction [Estradiol results in decreased phosphorylation of SMAD3 protein] | 24308608|2640794 |
| D004958 | Estradiol | Genistein inhibits the reaction [Estradiol results in decreased phosphorylation of SMAD3 protein] | 26407941 |
| C002503 | betulin | betulin inhibits the reaction [Ethanol results in increased phosphorylation of SMAD3 protein] | 21172400 |
| C002070 | betulinic acid | betulinic acid inhibits the reaction [Ethanol results in increased phosphorylation of SMAD3 protein] | 21172400 |
| D001647 | Bile Acids and Salts | SMAD3 protein results in increased metabolism of Bile Acids and Salts | 23034213 |
| D001688 | Biological Products | Biological Products results in decreased expression of SMAD3 mRNA | 23624380 |
| C006780 | bisphenol A | bisphenol A results in decreased phosphorylation of SMAD3 protein | 24308608|2640794 |
| C006780 | bisphenol A | bisphenol A results in increased methylation of SMAD3 promoter | 27271280 |
| C006780 | bisphenol A | fulvestrant inhibits the reaction [bisphenol A results in decreased phosphorylation of SMAD3 protein] | 24308608|2640794 |
| C006780 | bisphenol A | Genistein inhibits the reaction [bisphenol A results in decreased phosphorylation of SMAD3 protein] | 26407941 |
| C006780 | bisphenol A | bisphenol A affects the methylation of SMAD3 promoter | 27334623 |
| D001761 | Bleomycin | "2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]" | 27704718 |
| D001761 | Bleomycin | Bleomycin results in increased phosphorylation of SMAD3 protein | 27704718 |
| D001761 | Bleomycin | Bleomycin results in increased expression of SMAD3 mRNA | 26093215 |
| D001761 | Bleomycin | Phytochemicals inhibits the reaction [Bleomycin results in increased expression of SMAD3 mRNA] | 26093215 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of SMAD3 mRNA | 27509014 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased methylation of SMAD3 gene | 27509014 |
| C018475 | butyraldehyde | butyraldehyde results in decreased expression of SMAD3 mRNA | 26079696 |
| C584509 | C646 compound | C646 compound inhibits the reaction [Glucose results in increased phosphorylation of SMAD3 protein] | 26045780 |
| D002110 | Caffeine | "[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of SMAD3 mRNA" | 20230807 |
| D002110 | Caffeine | "Caffeine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SMAD3 mRNA]" | 20230807 |
| C081643 | candesartan | [benazepril co-treated with candesartan] results in decreased expression of SMAD3 protein | 19487956 |
| C077793 | candesartan cilexetil | candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of SMAD3 protein modified form] | 27889505 |
| D002220 | Carbamazepine | Carbamazepine affects the expression of SMAD3 mRNA | 25979313 |
| D002235 | Carbofuran | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased phosphorylation of SMAD3 protein]" | 28982980 |
| D002235 | Carbofuran | Carbofuran results in increased expression of SMAD3 mRNA | 28982980 |
| D002235 | Carbofuran | Carbofuran results in increased phosphorylation of SMAD3 protein | 28982980 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride inhibits the reaction [HGF protein affects the localization of SMAD3 protein] | 18395096 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of SMAD3 mRNA | 18395914|2629798 |
| D002251 | Carbon Tetrachloride | chrysin inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 mRNA] | 26297989 |
| D002251 | Carbon Tetrachloride | oxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 mRNA] | 18395914 |
| D002251 | Carbon Tetrachloride | Silymarin inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 mRNA] | 26297989 |
| D002251 | Carbon Tetrachloride | SMAD3 protein affects the susceptibility to Carbon Tetrachloride | 16382155 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased activity of SMAD3 protein | 17009398 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of SMAD3 mRNA | 15818738 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of SMAD3 protein | 15818738|1687230 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased phosphorylation of SMAD3 protein | 24211420|2515014 |
| D002251 | Carbon Tetrachloride | "Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 mRNA]" | 15818738 |
| D002251 | Carbon Tetrachloride | "Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 protein]" | 15818738|1716359 |
| D002251 | Carbon Tetrachloride | Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 protein] | 16872305 |
| D002251 | Carbon Tetrachloride | Valsartan inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 protein] | 16872305 |
| C054133 | casticin | casticin results in increased expression of SMAD3 mRNA | 27862857 |
| D002784 | Cholesterol | "[Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of SMAD3 mRNA" | 22129739 |
| D002794 | Choline | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SMAD3 gene | 20938992 |
| D002794 | Choline | [Methionine deficiency co-treated with Choline deficiency] results in increased expression of SMAD3 mRNA | 22915297 |
| D002794 | Choline | Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SMAD3 mRNA] | 22915297 |
| C043561 | chrysin | chrysin inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 mRNA] | 26297989 |
| D003042 | Cocaine | Cocaine deficiency promotes the reaction [SMARCA4 protein binds to SMAD3 protein] | 27422367 |
| C024989 | coenzyme Q10 | coenzyme Q10 inhibits the reaction [sodium arsenite results in increased expression of SMAD3 mRNA] | 27174133 |
| D003300 | Copper | [Disulfiram binds to Copper] which results in increased expression of SMAD3 mRNA | 24690739 |
| D019327 | Copper Sulfate | Copper Sulfate results in increased expression of SMAD3 mRNA | 19549813 |
| D003375 | Coumestrol | "[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SMAD3 mRNA" | 19167446 |
| D003375 | Coumestrol | Coumestrol results in decreased expression of SMAD3 mRNA | 19167446 |
| D003474 | Curcumin | Curcumin inhibits the reaction [[SMAD4 protein binds to SMAD3 protein] which binds to PPARG promoter] | 16959952 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of SMAD3 mRNA | 25562108 |
| D016572 | Cyclosporine | Cyclosporine results in increased methylation of SMAD3 promoter | 27989131 |
| D015638 | Cytochalasin D | Cytochalasin D affects the localization of SMAD3 protein | 25756282 |
| C014347 | decitabine | decitabine results in increased expression of SMAD3 mRNA | 27915011 |
| C014347 | decitabine | decitabine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 24211420 |
| C107676 | deguelin | deguelin results in decreased phosphorylation of SMAD3 protein | 22986522 |
| D003907 | Dexamethasone | Dexamethasone affects the expression of SMAD3 mRNA | 21277400 |
| C041517 | dibenzo(a,l)pyrene | "[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of SMAD3 mRNA" | 18711122 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in increased expression of SMAD3 mRNA | 21266533 |
| D002945 | Cisplatin | [Cisplatin co-treated with Paclitaxel] results in decreased expression of SMAD3 mRNA | 20705681 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of SMAD3 mRNA | 19561079 |
| D002945 | Cisplatin | Cisplatin results in increased expression of SMAD3 mRNA | 27392435 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of SMAD3 protein | 23628706 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of SMAD3 mRNA | 18042831 |
| D004052 | Diethylnitrosamine | [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein | 15368444 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine affects the phosphorylation of SMAD3 protein | 19418558 |
| D004052 | Diethylnitrosamine | IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein] | 15368444 |
| D004052 | Diethylnitrosamine | pyrazolanthrone inhibits the reaction [Diethylnitrosamine affects the phosphorylation of SMAD3 protein] | 19418558 |
| D004221 | Disulfiram | [Disulfiram binds to Copper] which results in increased expression of SMAD3 mRNA | 24690739 |
| D004281 | Docosahexaenoic Acids | SMAD3 protein results in decreased abundance of Docosahexaenoic Acids | 23034213 |
| D004317 | Doxorubicin | Doxorubicin inhibits the reaction [TGFB1 protein results in increased localization of SMAD3 protein] | 18606404 |
| D004317 | Doxorubicin | Doxorubicin results in decreased expression of SMAD3 protein | 18606404 |
| D004365 | Drugs, Chinese Herbal | "Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 mRNA]" | 15818738 |
| D004365 | Drugs, Chinese Herbal | "Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 protein]" | 15818738|1716359 |
| C042986 | ebselen | ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 21131394 |
| C031818 | enterotoxin B, staphylococcal | "enterotoxin B, staphylococcal results in decreased expression of SMAD3 mRNA" | 25556216 |
| C045651 | epigallocatechin gallate | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SMAD3 mRNA | 22079256 |
| D000431 | Ethanol | "8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide inhibits the reaction [Ethanol results in increased phosphorylation of SMAD3 protein]" | 22063920 |
| D000431 | Ethanol | betulinic acid inhibits the reaction [Ethanol results in increased phosphorylation of SMAD3 protein] | 21172400 |
| D000431 | Ethanol | betulin inhibits the reaction [Ethanol results in increased phosphorylation of SMAD3 protein] | 21172400 |
| D000431 | Ethanol | Ethanol results in increased expression of SMAD3 protein | 23274713 |
| D000431 | Ethanol | Ethanol results in increased phosphorylation of SMAD3 protein | 21172400|2206392 |
| D000431 | Ethanol | Genistein inhibits the reaction [Ethanol results in increased expression of SMAD3 protein] | 23274713 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of SMAD3 mRNA | 17942748 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of SMAD3 mRNA | 17942748 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in increased expression of SMAD3 mRNA | 23649840 |
| D011345 | Fenofibrate | Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA] | 19593819 |
| D011345 | Fenofibrate | NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]] | 19593819 |
| C082360 | fipronil | fipronil results in decreased expression of SMAD3 mRNA | 23962444 |
| C007738 | fluoranthene | [1-methylanthracene co-treated with fluoranthene] results in increased expression of SMAD3 mRNA | 28329830 |
| C007738 | fluoranthene | [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of SMAD3 mRNA | 18711122 |
| D015073 | 2-Acetylaminofluorene | [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein | 15368444 |
| D015073 | 2-Acetylaminofluorene | IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein] | 15368444 |
| D005492 | Folic Acid | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SMAD3 gene | 20938992 |
| D005557 | Formaldehyde | Formaldehyde results in increased expression of SMAD3 mRNA | 23649840 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [4-nonylphenol results in decreased phosphorylation of SMAD3 protein] | 24308608 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [benzophenone results in decreased phosphorylation of SMAD3 protein] | 24308608 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [bisphenol A results in decreased phosphorylation of SMAD3 protein] | 24308608|2640794 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Estradiol results in decreased phosphorylation of SMAD3 protein] | 24308608|2640794 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [nonylphenol results in decreased phosphorylation of SMAD3 protein] | 26407941 |
| D005688 | Galactosamine | Galactosamine results in increased phosphorylation of SMAD3 protein | 27876602 |
| D005688 | Galactosamine | Genistein inhibits the reaction [Galactosamine results in increased phosphorylation of SMAD3 protein] | 27876602 |
| C037032 | galangin | galangin results in increased expression of SMAD3 mRNA | 25268046 |
| C037032 | galangin | galangin results in increased phosphorylation of SMAD3 protein | 25268046 |
| C037032 | galangin | LY2109761 inhibits the reaction [galangin results in increased phosphorylation of SMAD3 protein] | 25268046 |
| D019833 | Genistein | Genistein inhibits the reaction [bisphenol A results in decreased phosphorylation of SMAD3 protein] | 26407941 |
| D019833 | Genistein | Genistein inhibits the reaction [Estradiol results in decreased phosphorylation of SMAD3 protein] | 26407941 |
| D019833 | Genistein | Genistein inhibits the reaction [nonylphenol results in decreased phosphorylation of SMAD3 protein] | 26407941 |
| D019833 | Genistein | Genistein results in decreased expression of SMAD3 mRNA | 22228119 |
| D019833 | Genistein | Genistein results in decreased expression of SMAD3 protein | 22228119 |
| D019833 | Genistein | SMAD3 protein affects the susceptibility to Genistein | 22228119 |
| D019833 | Genistein | Genistein inhibits the reaction [Ethanol results in increased expression of SMAD3 protein] | 23274713 |
| D019833 | Genistein | Genistein inhibits the reaction [Galactosamine results in increased phosphorylation of SMAD3 protein] | 27876602 |
| D005947 | Glucose | C646 compound inhibits the reaction [Glucose results in increased phosphorylation of SMAD3 protein] | 26045780 |
| D005947 | Glucose | Glucose results in increased phosphorylation of and affects the localization of SMAD3 protein | 17597607 |
| D005947 | Glucose | Glucose results in increased phosphorylation of SMAD3 protein | 26045780 |
| D005947 | Glucose | protocatechualdehyde inhibits the reaction [Glucose results in increased phosphorylation of and affects the localization of SMAD3 protein] | 17597607 |
| D056604 | Grape Seed Extract | Grape Seed Extract inhibits the reaction [Arsenic results in increased expression of SMAD3 protein modified form] | 24348802 |
| D056604 | Grape Seed Extract | Grape Seed Extract inhibits the reaction [sodium arsenite results in increased phosphorylation of SMAD3 protein] | 21605584 |
| C010176 | halofuginone | halofuginone inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 17180598 |
| C010176 | halofuginone | halofuginone inhibits the reaction [TGFB1 protein results in increased phosphorylation of and results in increased activity of SMAD3 protein] | 11874485 |
| D006581 | Hexachlorobenzene | AG 1879 inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of SMAD3 protein] | 27519288 |
| D006581 | Hexachlorobenzene | alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of SMAD3 protein] | 27519288 |
| D006581 | Hexachlorobenzene | Hexachlorobenzene results in increased phosphorylation of and affects the localization of SMAD3 protein | 27519288 |
| D006581 | Hexachlorobenzene | Hexachlorobenzene results in increased phosphorylation of SMAD3 protein | 28923513 |
| C005499 | honokiol | honokiol inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 21265825 |
| D017313 | Fenretinide | Fenretinide results in increased expression of SMAD3 mRNA | 28973697 |
| D006820 | Hyaluronic Acid | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]" | 21520325 |
| D006820 | Hyaluronic Acid | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid]" | 21520325 |
| D006820 | Hyaluronic Acid | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [EGF protein results in increased chemical synthesis of Hyaluronic Acid]" | 21520325 |
| D006820 | Hyaluronic Acid | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [EGF protein results in increased chemical synthesis of Hyaluronic Acid]" | 21520325 |
| D006861 | Hydrogen Peroxide | arsenic trioxide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of SMAD3 protein] | 24762191 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide inhibits the reaction [arsenic trioxide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]] | 24762191 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide promotes the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 24762191 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased phosphorylation of SMAD3 protein | 15147944|2476219 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased secretion of SMAD3 mRNA | 21179422 |
| C081309 | irbesartan | [benazepril co-treated with irbesartan] affects the expression of SMAD3 mRNA | 16635409 |
| C081309 | irbesartan | [benazepril co-treated with irbesartan] affects the expression of SMAD3 protein | 16635409 |
| C081309 | irbesartan | irbesartan affects the expression of SMAD3 mRNA | 16635409 |
| C081309 | irbesartan | irbesartan affects the expression of SMAD3 protein | 16635409 |
| C051890 | irinotecan | irinotecan analog results in decreased expression of SMAD3 mRNA | 18927307 |
| C038753 | leptomycin B | leptomycin B inhibits the reaction [arsenite inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]] | 26354774 |
| C038753 | leptomycin B | leptomycin B inhibits the reaction [arsenite inhibits the reaction [XPO4 protein results in increased export of SMAD3 protein]] | 26354774 |
| C038753 | leptomycin B | leptomycin B inhibits the reaction [monomethylarsonous acid inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]] | 26354774 |
| C038753 | leptomycin B | leptomycin B inhibits the reaction [monomethylarsonous acid inhibits the reaction [XPO4 protein results in increased export of SMAD3 protein]] | 26354774 |
| C482199 | lipopolysaccharide, E coli O55-B5 | "lipopolysaccharide, E coli O55-B5 results in decreased expression of SMAD3 mRNA" | 26961602 |
| C482199 | lipopolysaccharide, E coli O55-B5 | "lipopolysaccharide, E coli O55-B5 results in decreased expression of SMAD3 protein" | 26961602 |
| C440499 | lipopolysaccharide, Escherichia coli O111 B4 | "lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of SMAD3 protein" | 25234611 |
| C440499 | lipopolysaccharide, Escherichia coli O111 B4 | "resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of SMAD3 protein]" | 25234611 |
| D008070 | Lipopolysaccharides | IRAK1 protein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of SMAD3 protein] | 21295571 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides inhibits the reaction [TGFB1 protein results in increased activity of SMAD3 protein] | 21295571 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased phosphorylation of SMAD3 protein | 21295571 |
| D008070 | Lipopolysaccharides | [Lipopolysaccharides results in increased phosphorylation of SMAD3 protein] promotes the reaction [Lipopolysaccharides inhibits the reaction [TGFB1 protein results in increased expression of SMAD6 mRNA]] | 21295571 |
| D008070 | Lipopolysaccharides | MAP2K1 protein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of SMAD3 protein] | 21295571 |
| D008070 | Lipopolysaccharides | SMAD3 protein modified form promotes the reaction [Lipopolysaccharides inhibits the reaction [TGFB1 protein results in increased expression of SMAD6 mRNA]] | 21295571 |
| D008070 | Lipopolysaccharides | SMAD3 protein results in increased susceptibility to Lipopolysaccharides | 21131441 |
| D008070 | Lipopolysaccharides | TLR4 protein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of SMAD3 protein] | 21295571 |
| D008070 | Lipopolysaccharides | U 0126 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of SMAD3 protein] | 21295571 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in decreased expression of SLC10A1 mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of ABCC1 mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of ABCC4 mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of CHKA mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of LPCAT1 mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of LPCAT2 mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of LPCAT4 mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of PCYT1B mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of PLD1 mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of PLD2 mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of SLC51B mRNA] | 23034213 |
| D008095 | Lithocholic Acid | SMAD3 protein results in increased susceptibility to Lithocholic Acid | 23034213 |
| C530108 | LY2109761 | LY2109761 inhibits the reaction [galangin results in increased phosphorylation of SMAD3 protein] | 25268046 |
| C520284 | Ly-364947 | Ly-364947 inhibits the reaction [TGFB3 protein results in increased expression of SMAD3 protein modified form] | 25566828 |
| C015329 | lycopene | lycopene results in increased expression of SMAD3 mRNA | 16886892 |
| D008558 | Melphalan | Melphalan results in decreased expression of SMAD3 mRNA | 22363485 |
| D008694 | Methamphetamine | [Methamphetamine co-treated with SCH 23390] results in increased expression of SMAD3 mRNA | 19564919 |
| D008694 | Methamphetamine | Methamphetamine results in increased expression of SMAD3 mRNA | 19564919 |
| D008715 | Methionine | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SMAD3 gene | 20938992 |
| D008715 | Methionine | [Methionine deficiency co-treated with Choline deficiency] results in increased expression of SMAD3 mRNA | 22915297 |
| D008715 | Methionine | Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SMAD3 mRNA] | 22915297 |
| D008746 | Methylazoxymethanol Acetate | Methylazoxymethanol Acetate results in increased expression of SMAD3 mRNA | 28349193 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of SMAD3 mRNA | 28001369 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of SMAD3 mRNA | 20061341 |
| D018817 | N-Methyl-3,4-methylenedioxyamphetamine | "N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SMAD3 mRNA" | 20188158 |
| D015632 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | "1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SMAD3 mRNA" | 20230807 |
| D015632 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | "[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of SMAD3 mRNA" | 20230807 |
| D015632 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | "Caffeine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SMAD3 mRNA]" | 20230807 |
| D015632 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | "[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SMAD3 mRNA" | 20230807 |
| D015632 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | "Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SMAD3 mRNA]" | 20230807 |
| C035133 | mirtazapine | mirtazapine inhibits the reaction [Thioacetamide results in increased expression of SMAD3 protein modified form] | 28623179 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in increased expression of SMAD3 mRNA | 19945496 |
| C406082 | monomethylarsonous acid | leptomycin B inhibits the reaction [monomethylarsonous acid inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]] | 26354774 |
| C406082 | monomethylarsonous acid | leptomycin B inhibits the reaction [monomethylarsonous acid inhibits the reaction [XPO4 protein results in increased export of SMAD3 protein]] | 26354774 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein] | 26354774 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid inhibits the reaction [TGFB2 protein results in increased localization of SMAD3 protein] | 25145660 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid inhibits the reaction [XPO4 protein results in increased export of SMAD3 protein] | 26354774 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in decreased activity of SMAD3 protein | 25145660 |
| C406082 | monomethylarsonous acid | Zinc inhibits the reaction [monomethylarsonous acid inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]] | 26354774 |
| C500085 | muraglitazar | muraglitazar results in decreased expression of SMAD3 mRNA | 21515302 |
| D009151 | Mustard Gas | Mustard Gas results in decreased expression of SMAD3 mRNA | 15674843 |
| C005274 | naringin | naringin inhibits the reaction [sodium arsenite results in increased expression of SMAD3 mRNA] | 27174133 |
| D064729 | Neurokinin-1 Receptor Antagonists | Neurokinin-1 Receptor Antagonists inhibits the reaction [TAC1 protein modified form results in increased phosphorylation of SMAD3 protein] | 28647476 |
| D064729 | Neurokinin-1 Receptor Antagonists | Neurokinin-1 Receptor Antagonists inhibits the reaction [TAC1 protein modified form results in increased phosphorylation of SMAD3 protein] | 28647476 |
| D009538 | Nicotine | "[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SMAD3 mRNA" | 20230807 |
| D009538 | Nicotine | "Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SMAD3 mRNA]" | 20230807 |
| D009569 | Nitric Oxide | Nitric Oxide results in increased activity of [SMAD4 protein binds to SMAD3 protein] | 15949472 |
| D009569 | Nitric Oxide | [SMAD4 protein co-treated with SMAD3 protein] affects the susceptibility to Nitric Oxide | 15949472 |
| C007350 | nitrofen | nitrofen results in decreased expression of SMAD3 mRNA | 12149686 |
| C572573 | N-nitroso-tris-chloroethylurea | N-nitroso-tris-chloroethylurea results in increased expression of SMAD3 mRNA | 27935865 |
| C025256 | nonylphenol | fulvestrant inhibits the reaction [nonylphenol results in decreased phosphorylation of SMAD3 protein] | 26407941 |
| C025256 | nonylphenol | Genistein inhibits the reaction [nonylphenol results in decreased phosphorylation of SMAD3 protein] | 26407941 |
| C025256 | nonylphenol | nonylphenol results in decreased phosphorylation of SMAD3 protein | 26407941 |
| C559056 | NPLC 0393 | NPLC 0393 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 21151953 |
| C559056 | NPLC 0393 | NPLC 0393 results in decreased phosphorylation of and results in decreased localization of SMAD3 protein | 21151953 |
| C559056 | NPLC 0393 | PPP2CA protein affects the reaction [NPLC 0393 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]] | 21151953 |
| C559056 | NPLC 0393 | PPP2CA protein affects the reaction [NPLC 0393 results in decreased phosphorylation of and results in decreased localization of SMAD3 protein] | 21151953 |
| C559056 | NPLC 0393 | NPLC 0393 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 21151953 |
| C559056 | NPLC 0393 | NPLC 0393 results in decreased phosphorylation of and results in decreased localization of SMAD3 protein | 21151953 |
| D019787 | Linoleic Acid | SMAD3 protein results in decreased abundance of Linoleic Acid | 23034213 |
| D010100 | Oxygen | Oxygen affects the reaction [AHR protein results in decreased expression of SMAD3 mRNA] | 27103661 |
| D010100 | Oxygen | Oxygen deficiency results in increased expression of SMAD3 mRNA | 24205000 |
| C037573 | oxymatrine | oxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 mRNA] | 18395914 |
| D017239 | Paclitaxel | [Cisplatin co-treated with Paclitaxel] results in decreased expression of SMAD3 mRNA | 20705681 |
| D000073878 | Palm Oil | Palm Oil results in decreased expression of SMAD3 mRNA | 18042831 |
| D010269 | Paraquat | Paraquat results in increased expression of SMAD3 protein modified form | 27682480 |
| D010269 | Paraquat | TGFB1 protein promotes the reaction [Paraquat results in increased expression of SMAD3 protein modified form] | 27682480 |
| D010269 | Paraquat | SMAD3 protein results in increased susceptibility to Paraquat | 22581813 |
| D010426 | Pentosan Sulfuric Polyester | Pentosan Sulfuric Polyester results in increased expression of SMAD3 mRNA | 28973697 |
| D020913 | Perindopril | Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 protein] | 16872305 |
| D020913 | Perindopril | Perindopril results in decreased expression of SMAD3 protein | 15619341 |
| D010696 | Phloroglucinol | Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 26054450 |
| D010743 | Phospholipids | SMAD3 protein results in increased metabolism of Phospholipids | 23034213 |
| D064209 | Phytochemicals | Phytochemicals inhibits the reaction [Bleomycin results in increased expression of SMAD3 mRNA] | 26093215 |
| D010852 | Picrotoxin | Picrotoxin results in increased expression of SMAD3 mRNA | 15170462 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of SMAD3 mRNA | 20813756 |
| C027373 | potassium chromate(VI) | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SMAD3 mRNA | 22079256 |
| C027373 | potassium chromate(VI) | potassium chromate(VI) results in decreased expression of SMAD3 mRNA | 22079256|2271453 |
| D011374 | Progesterone | Progesterone results in decreased expression of SMAD3 mRNA | 20631399 |
| D011374 | Progesterone | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] promotes the reaction [FSHB protein results in increased chemical synthesis of Progesterone]" | 21520325 |
| D011374 | Progesterone | "[6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride results in decreased activity of SMAD3 protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Progesterone]" | 21520325 |
| D011374 | Progesterone | [Estradiol co-treated with Progesterone] results in decreased expression of SMAD3 mRNA | 20660070 |
| D011374 | Progesterone | Progesterone results in decreased expression of SMAD3 mRNA | 20864642 |
| C005581 | protocatechualdehyde | protocatechualdehyde inhibits the reaction [Glucose results in increased phosphorylation of and affects the localization of SMAD3 protein] | 17597607 |
| C005581 | protocatechualdehyde | protocatechualdehyde inhibits the reaction [S100B protein results in increased phosphorylation of and affects the localization of SMAD3 protein] | 17597607 |
| C432165 | pyrazolanthrone | pyrazolanthrone inhibits the reaction [Diethylnitrosamine affects the phosphorylation of SMAD3 protein] | 19418558 |
| D011794 | Quercetin | Quercetin inhibits the reaction [SMAD2 protein modified form binds to SMAD3 protein modified form binds to SMAD4 protein] | 15580028 |
| D011794 | Quercetin | Quercetin results in decreased expression of SMAD3 protein | 15580028 |
| D011794 | Quercetin | Quercetin results in decreased expression of SMAD3 protein modified form | 15580028 |
| D011794 | Quercetin | Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SMAD3 mRNA] | 22915297 |
| D011794 | Quercetin | Quercetin promotes the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 21216973 |
| C012526 | quercitrin | quercitrin results in increased expression of SMAD3 mRNA | 25193878 |
| D017382 | Reactive Oxygen Species | Reactive Oxygen Species affects the expression of SMAD3 mRNA | 25800948 |
| C059514 | resveratrol | resveratrol inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 27345520 |
| C059514 | resveratrol | resveratrol results in decreased expression of SMAD3 mRNA | 25721869 |
| C059514 | resveratrol | resveratrol results in decreased expression of SMAD3 protein | 18089832|2572186 |
| C059514 | resveratrol | "resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of SMAD3 protein]" | 25234611 |
| C059514 | resveratrol | resveratrol results in decreased acetylation of SMAD3 protein | 20651248 |
| C059514 | resveratrol | resveratrol results in decreased phosphorylation of SMAD3 protein | 21679764 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD3 protein] | 21300041 |
| C059514 | resveratrol | resveratrol results in decreased acetylation of SMAD3 protein | 20651248 |
| C059514 | resveratrol | resveratrol inhibits the reaction [TGFB1 protein results in increased acetylation of SMAD3 protein] | 20651248 |
| C059514 | resveratrol | SIRT1 protein affects the reaction [resveratrol inhibits the reaction [TGFB1 protein results in increased acetylation of SMAD3 protein]] | 20651248 |
| C089730 | rosiglitazone | rosiglitazone results in decreased expression of SMAD3 mRNA | 21515302 |
| C410958 | sauchinone | sauchinone inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 25451574 |
| C093642 | SB 203580 | SB 203580 inhibits the reaction [TGFB2 protein results in increased phosphorylation of SMAD3 protein] | 18253093 |
| C534628 | SCH 23390 | [Methamphetamine co-treated with SCH 23390] results in increased expression of SMAD3 mRNA | 19564919 |
| C534628 | SCH 23390 | SCH 23390 results in increased expression of SMAD3 mRNA | 19564919 |
| D017632 | Asbestos, Serpentine | "[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of and results in increased phosphorylation of SMAD3 protein" | 25358858 |
| D017632 | Asbestos, Serpentine | "[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of SMAD3 mRNA" | 25358858 |
| C009250 | sevoflurane | SMAD3 protein affects the susceptibility to sevoflurane | 18434384 |
| C009250 | sevoflurane | TGFB1 protein affects the reaction [sevoflurane affects the localization of SMAD3 protein] | 18434384 |
| D012834 | Silver | Silver results in increased expression of SMAD3 mRNA | 28959546 |
| D012835 | Silver Nitrate | Silver Nitrate analog results in decreased expression of SMAD3 mRNA | 22831968 |
| D012835 | Silver Nitrate | Silver Nitrate results in increased expression of SMAD3 mRNA | 22831968 |
| D012838 | Silymarin | Silymarin inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 mRNA] | 26297989 |
| D019821 | Simvastatin | Simvastatin results in increased expression of SMAD3 mRNA | 18310456 |
| D019821 | Simvastatin | Simvastatin results in decreased phosphorylation of SMAD3 protein | 19659652 |
| C110881 | S-nitro-N-acetylpenicillamine | S-nitro-N-acetylpenicillamine results in increased activity of [SMAD4 protein binds to SMAD3 protein] | 15949472 |
| C009277 | sodium arsenate | sodium arsenate results in increased expression of SMAD3 mRNA | 21795629 |
| C017947 | sodium arsenite | IFNG protein inhibits the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of SMAD3 protein] | 17003472 |
| C017947 | sodium arsenite | sodium arsenite inhibits the reaction [TGFB2 protein results in increased phosphorylation of and affects the localization of SMAD3 protein] | 23732083 |
| C017947 | sodium arsenite | sodium arsenite results in decreased phosphorylation of SMAD3 protein | 23732083 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of and results in increased phosphorylation of SMAD3 protein | 17003472 |
| C017947 | sodium arsenite | candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of SMAD3 protein modified form] | 27889505 |
| C017947 | sodium arsenite | coenzyme Q10 inhibits the reaction [sodium arsenite results in increased expression of SMAD3 mRNA] | 27174133 |
| C017947 | sodium arsenite | Grape Seed Extract inhibits the reaction [sodium arsenite results in increased phosphorylation of SMAD3 protein] | 21605584 |
| C017947 | sodium arsenite | naringin inhibits the reaction [sodium arsenite results in increased expression of SMAD3 mRNA] | 27174133 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of SMAD3 mRNA | 27174133 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of SMAD3 protein modified form | 27889505 |
| C017947 | sodium arsenite | sodium arsenite results in increased phosphorylation of SMAD3 protein | 21605584 |
| D012969 | Sodium Fluoride | "[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Sodium Fluoride] results in decreased phosphorylation of SMAD3 protein" | 29127033 |
| D012969 | Sodium Fluoride | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Sodium Fluoride results in increased expression of SMAD3 mRNA]" | 29127033 |
| D012969 | Sodium Fluoride | Sodium Fluoride results in increased expression of SMAD3 mRNA | 29127033 |
| D018038 | Sodium Selenite | Sodium Selenite results in increased expression of SMAD3 mRNA | 18175754 |
| C471405 | sorafenib | sorafenib affects the localization of SMAD3 protein | 21360571 |
| C471405 | sorafenib | sorafenib inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] | 21360571 |
| D013311 | Streptozocin | resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD3 protein] | 21300041 |
| D013311 | Streptozocin | Streptozocin results in increased phosphorylation of SMAD3 protein | 21300041 |
| D013629 | Tamoxifen | Tamoxifen promotes the reaction [Tretinoin results in increased phosphorylation of SMAD3 protein] | 17098229 |
| D013629 | Tamoxifen | Tamoxifen results in increased phosphorylation of SMAD3 protein | 17098229 |
| D013655 | Taurochenodeoxycholic Acid | SMAD3 protein results in increased abundance of Taurochenodeoxycholic Acid | 23034213 |
| D013658 | Taurolithocholic Acid | SMAD3 protein results in increased abundance of Taurolithocholic Acid | 23034213 |
| C037351 | tauromuricholic acid | SMAD3 protein results in increased abundance of tauromuricholic acid | 23034213 |
| C031655 | tauroursodeoxycholic acid | SMAD3 protein results in increased abundance of tauroursodeoxycholic acid | 23034213 |
| C501413 | tesaglitazar | tesaglitazar results in decreased expression of SMAD3 mRNA | 21515302 |
| D013739 | Testosterone | Testosterone results in increased expression of SMAD3 mRNA | 22138414 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of SMAD3 mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of SMAD3 mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of SMAD3 mRNA | 25975270 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of SMAD3 mRNA | 24058054 |
| D013853 | Thioacetamide | mirtazapine inhibits the reaction [Thioacetamide results in increased expression of SMAD3 protein modified form] | 28623179 |
| D013853 | Thioacetamide | Thioacetamide results in increased expression of SMAD3 protein modified form | 28623179 |
| C423915 | TO-901317 | [TO-901317 co-treated with alitretinoin] results in increased expression of SMAD3 protein | 17194744 |
| D014028 | Tobacco Smoke Pollution | SMAD3 protein affects the reaction [Tobacco Smoke Pollution results in increased secretion of VEGFA protein] | 23618901 |
| D014212 | Tretinoin | SMAD3 protein inhibits the reaction [Tretinoin results in decreased expression of FBN2] | 24374174 |
| D014212 | Tretinoin | SMAD3 protein inhibits the reaction [Tretinoin results in decreased expression of FN1] | 24374174 |
| D014212 | Tretinoin | SMAD3 protein inhibits the reaction [Tretinoin results in decreased expression of TNC] | 24374174 |
| D014212 | Tretinoin | Tamoxifen promotes the reaction [Tretinoin results in increased phosphorylation of SMAD3 protein] | 17098229 |
| D014212 | Tretinoin | Tretinoin results in decreased phosphorylation of SMAD3 protein | 24374174 |
| D014212 | Tretinoin | Tretinoin results in increased expression of SMAD3 mRNA | 16012519|1743110 |
| D014212 | Tretinoin | Tretinoin results in increased phosphorylation of SMAD3 protein | 17098229 |
| D014212 | Tretinoin | Tretinoin results in decreased phosphorylation of SMAD3 protein | 16410076 |
| C012589 | trichostatin A | trichostatin A affects the expression of SMAD3 mRNA | 28542535 |
| C057693 | troglitazone | troglitazone inhibits the reaction [TGFB2 protein results in increased phosphorylation of and affects the localization of SMAD3 protein] | 18253093 |
| C057693 | troglitazone | troglitazone results in decreased expression of SMAD3 mRNA | 21515302 |
| C057693 | troglitazone | troglitazone inhibits the reaction [TGFB1 protein results in increased expression of SMAD3 protein] | 19120328 |
| C113580 | U 0126 | U 0126 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of SMAD3 protein] | 21295571 |
| D014580 | Ursodeoxycholic Acid | Ursodeoxycholic Acid results in decreased expression of SMAD3 mRNA | 19493473 |
| D014580 | Ursodeoxycholic Acid | Ursodeoxycholic Acid results in decreased expression of SMAD3 protein | 19493473 |
| D014635 | Valproic Acid | Valproic Acid results in increased methylation of SMAD3 gene | 28853863|2915479 |
| D000068756 | Valsartan | Valsartan inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 protein] | 16872305 |
| D000068756 | Valsartan | Valsartan results in decreased expression of SMAD3 protein | 15619341 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in decreased methylation of SMAD3 gene | 25560391 |
| D014810 | Vitamin E | Vitamin E results in increased expression of SMAD3 mRNA | 19244175 |
| D024483 | Vitamin K 3 | Vitamin K 3 affects the expression of SMAD3 mRNA | 20044591 |
| C521629 | Wen-pi-tang-Hab-Wu-ling-san | Wen-pi-tang-Hab-Wu-ling-san affects the phosphorylation of SMAD3 protein | 19913069 |
| D015032 | Zinc | Zinc inhibits the reaction [arsenite inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]] | 26354774 |
| D015032 | Zinc | Zinc inhibits the reaction [monomethylarsonous acid inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]] | 26354774 |
| D015032 | Zinc | Zinc promotes the reaction [SMAD3 protein modified form binds to SMAD2 protein modified form binds to NFIC protein] | 22228435 |
| D015032 | Zinc | Zinc results in increased stability of and results in increased activity of SMAD3 protein | 26354774 |
| C088658 | zoledronic acid | "4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [zoledronic acid results in increased phosphorylation of SMAD3 protein]" | 28871336 |
| C088658 | zoledronic acid | zoledronic acid results in increased expression of SMAD3 mRNA | 24714768 |
| C088658 | zoledronic acid | zoledronic acid results in increased phosphorylation of SMAD3 protein | 28871336 |
| C088658 | zoledronic acid | zoledronic acid results in increased phosphorylation of SMAD3 protein | 28871336 |
| C088658 | zoledronic acid | zoledronic acid results in increased phosphorylation of SMAD3 protein | 28871336 |