Gene: MAX

4149
bHLHd4
MYC associated factor X
protein-coding
14q23.3
Ensembl:ENSG00000125952 MIM:154950 Vega:OTTHUMG00000142809 UniprotKB:P61244
NG_029830.1
PubMed|SNP Mapped
CD|OD|ND|AD
117   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.141e-1 (AD)  4.085e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs12434868chr14:65033431 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)
rs7148144chr14:65032732 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DAXX0.915
SRSF40.912
TPD52L20.908
PCBP10.907
DNAJB20.906
AUP10.904
GPS20.901
HNRNPA2B10.9
ALKBH50.896
BANF10.895

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.804
OR4F29-0.792
SDR42E1-0.214
KRT73-0.21
MROH9-0.194
DDX47-0.19
AMPD1-0.183
OR51I2-0.183
KLRB1-0.181
XIRP2-0.179

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C53488310074-G510074-G5 affects the folding of and results in decreased activity of [MYC protein binds to MAX protein]26474287
C53488310074-G510074-G5 inhibits the reaction [MYC protein binds to MAX protein]26474287
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of MAX mRNA"21346803
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in decreased expression of MAX mRNA]28655636
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in decreased expression of MAX mRNA]28655636
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAX mRNA"27188386
C0821644-methoxycinnamate methyl ester4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of MAX mRNA]19442820
C5248145-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one affects the folding of and results in decreased activity of [MYC protein binds to MAX protein]26474287
C5248145-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one inhibits the reaction [MYC protein binds to MAX protein]26474287
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAX mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of MAX mRNA17562736
D020106AcrylamideAcrylamide results in increased expression of MAX mRNA28959563
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of MAX mRNA24449571
C006632arsenic trioxidearsenic trioxide affects the methylation of MAX promoter26046465
C006632arsenic trioxidearsenic trioxide results in decreased expression of MAX mRNA26046465
D001280AtrazineAtrazine results in increased expression of MAX mRNA22378314
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MAX mRNA"19150397
D004958EstradiolEstradiol results in increased expression of MAX mRNA15223131|1916744
D004958EstradiolIGF1R mutant form promotes the reaction [Estradiol results in increased expression of MAX mRNA]23094148
D004958EstradiolEstradiol results in increased expression of MAX mRNA20068009
C006780bisphenol Abisphenol A affects the expression of MAX mRNA21786754
C006780bisphenol Abisphenol A affects the expression of MAX mRNA21786754
C006780bisphenol Abisphenol A affects the expression of MAX mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of MAX gene28505145
C054133casticincasticin results in decreased expression of MAX mRNA28444820
D002713Chlorine[Ozone co-treated with Chlorine] results in decreased expression of MAX mRNA18636392
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of MAX mRNA23650126
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of MAX mRNA28472532
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of MAX mRNA20971185
D003375CoumestrolCoumestrol results in increased expression of MAX mRNA19167446
D016572CyclosporineCyclosporine results in increased expression of MAX mRNA20106945
C017180decamethrindecamethrin results in increased expression of MAX mRNA19017407
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of MAX mRNA]27941970
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of MAX mRNA26924002
D004147DioxinsDioxins affects the expression of MAX mRNA20463971
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of MAX mRNA]"19442820
D019833GenisteinGenistein results in increased expression of MAX mRNA26865667
D017313FenretinideFenretinide results in increased expression of MAX mRNA28973697
C016517indole-3-carbinolindole-3-carbinol affects the expression of MAX mRNA21396975
C410337K 7174K 7174 results in increased expression of MAX mRNA24086573
D007854LeadLead results in increased expression of MAX mRNA19921347
C013592mangiferinmangiferin results in decreased expression of MAX mRNA15135318
D008627Mercuric ChlorideMercuric Chloride affects the expression of MAX mRNA20353558
D008731MethoxychlorMethoxychlor results in decreased expression of MAX mRNA23303685
D008731MethoxychlorMethoxychlor results in increased methylation of MAX gene23303685
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased expression of MAX mRNA12634122
C517284monomethyl phthalatemonomethyl phthalate affects the expression of MAX mRNA26924002
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of MAX mRNA20971185
D010126Ozone[Ozone co-treated with Chlorine] results in decreased expression of MAX mRNA18636392
D052638Particulate Matter2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in decreased expression of MAX mRNA]28655636
D052638Particulate MatterParticulate Matter results in decreased expression of MAX mRNA28655636
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of MAX mRNA19710929
C059514resveratrolresveratrol results in decreased expression of MAX protein25505154
D012643SeleniumSelenium results in increased expression of MAX mRNA19244175
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of MAX mRNA25895662
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of MAX mRNA21570461|2405805
D019284Thapsigargin4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of MAX mRNA]19442820
D019284Thapsigargin"Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of MAX mRNA]"19442820
D019284ThapsigarginThapsigargin results in decreased expression of MAX mRNA19442820
D014118Toxins, Biological"Toxins, Biological affects the expression of MAX mRNA"19682533
D014212TretinoinTretinoin results in increased expression of MAX mRNA16054129
C050414tripterinetripterine affects the folding of and results in decreased activity of [MYC protein binds to MAX protein]26474287
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of MAX mRNA"26179874
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAX mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of MAX mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of MAX mRNA22083351|2317975
D001335Vehicle Emissions2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in decreased expression of MAX mRNA]28655636
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of MAX mRNA28655636
D014750VincristineVincristine results in decreased expression of MAX mRNA23649840
D015032ZincZinc deficiency results in increased expression of MAX mRNA11717422
C088658zoledronic acidzoledronic acid results in increased expression of MAX mRNA20977926

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IBA21873635  
GO:0000977RNA polymerase II regulatory region sequence-specific DNA bindingcontributes_toIDA8425219  8521822  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0000983transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding-IBA21873635  
GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IBA21873635  
GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IDA26070438  
GO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA bindingcontributes_toIDA8521822  
GO:0003677DNA binding-IMP9399572  
GO:0003700DNA-binding transcription factor activity-TAS2006410  
GO:0003712transcription coregulator activity-TAS8425218  
GO:0003713transcription coactivator activity-TAS2006410  
GO:0005515protein binding-IPI9680483  10597290  12821782  15674325  16189514  16352593  
16606833  17157259  17314511  17353931  17418410  18003922  
18620061  20195357  20691906  20936779  21150319  21807113  
21988832  23792191  24951594  25175806  25416956  25609649  
26267534  27705803  27728805  
GO:0042803protein homodimerization activity-IMP9399572  16171389  
GO:0044877protein-containing complex binding-IEA-  
GO:0046982protein heterodimerization activity-IEA-  
GO:0070888E-box binding-IMP16171389  
GO ID GO Term Qualifier Evidence PubMed
GO:0000082G1/S transition of mitotic cell cycle-TAS-  
GO:0000122negative regulation of transcription by RNA polymerase II-IDA8521822  
GO:0006366transcription by RNA polymerase II-TAS8425218  
GO:0009267cellular response to starvation-IEA-  
GO:0032868response to insulin-IEA-  
GO:0045944positive regulation of transcription by RNA polymerase II-IBA21873635  
GO:0048678response to axon injury-IEA-  
GO:0051402neuron apoptotic process-IEA-  
GO:0060041retina development in camera-type eye-IEA-  
GO:0065003protein-containing complex assembly-IEA-  
GO:0070317negative regulation of G0 to G1 transition-TAS-  
GO:0071375cellular response to peptide hormone stimulus-IEA-  
GO:1903508positive regulation of nucleic acid-templated transcription-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000790nuclear chromatin-IDA12837246  
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA15358760  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IEA-  
GO:0016605PML body-IEA-  
GO:0030425dendrite-IEA-  
GO:0032993protein-DNA complex-IMP9399572  16171389  
GO:0071339MLL1 complex-IDA15960975  
GO:0090575RNA polymerase II transcription factor complex-IBA21873635  
GO:0090575RNA polymerase II transcription factor complex-IDA8425219  8521822  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa05200Pathways in cancer
hsa05222Small cell lung cancer
Reactome ID Reactome Term Evidence
R-HSA-1362277Transcription of E2F targets under negative control by DREAM complexTAS
R-HSA-1538133G0 and Early G1TAS
R-HSA-1640170Cell CycleTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-453279Mitotic G1-G1/S phasesTAS
R-HSA-69202Cyclin E associated events during G1/S transition TAS
R-HSA-69206G1/S TransitionTAS
R-HSA-69242S PhaseTAS
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-69656Cyclin A:Cdk2-associated events at S phase entryTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8953750Transcriptional Regulation by E2F6TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28729620Self-management behaviour and support among primary care COPD patients: cross-sectional analysis of data from the Birmingham Chronic Obstructive Pulmonary Disease Cohort. (2017 Jul 20)Khan ANPJ Prim Care Respir Med
23053269Evaluation of the pharmacokinetics and safety of bosutinib in patients with chronic hepatic impairment and matched healthy subjects. (2013 Jan)Abbas RCancer Chemother Pharmacol
11318840Prolonged QTc interval predicts mortality in patients with Type 1 diabetes mellitus. (2001 Mar)Rossing PDiabet Med
19270316High serum YKL-40 concentration is associated with cardiovascular and all-cause mortality in patients with stable coronary artery disease. (2009 May)Kastrup JEur Heart J
20599802Role of transporter-mediated efflux in the placental biodisposition of bupropion and its metabolite, OH-bupropion. (2010 Oct 1)Hemauer SJBiochem Pharmacol
16499480Sex differences in the influence of COMT Val158Met on alcoholism and smoking in plains American Indians. (2006 Mar)Enoch MAAlcohol Clin Exp Res
17582987Influence of moderate smoking on physical fitness and local muscle oxygenation profile during incremental exercise. (2007 Jun 1)Kimura YJ UOEH
26001775Time course of cigarette smoke-induced changes of systemic inflammation and muscle structure. (2015 Jul 15)Kruger KAm J Physiol Lung Cell Mol Physiol
29614976Primary results of abdominal aortic aneurysm screening in the at-risk residents in middle China. (2018 Apr 3)Li KBMC Cardiovasc Disord
16681559Smoking enhances absorption of insulin but reduces glucodynamic effects in individuals using the Lilly-Dura inhaled insulin system. (2006 May)Wise SDiabet Med
22708121Juglans mandshurica leaf extract protects skin fibroblasts from damage by regulating the oxidative defense system. (2012 May 4)Park GBiochem Biophys Res Commun
28085949The Association between Exposure to Environmental Bisphenol A and Gonadotropic Hormone Levels among Men. (2017)Liang HPLoS One
12893989Mutations in mitochondrial aldehyde dehydrogenase (ALDH2) change cofactor affinity and segregate with voluntary alcohol consumption in rats. (2003 Aug)Sapag APharmacogenetics
14521778[A cross-sectional study on angiotensin-converting enzyme and angiotensin II type I receptor gene polymorphism and cerebral infarction]. (2003 Sep)Yuan XDZhonghua Liu Xing Bing Xue Za Zhi
2105105Thyrotropin and prolactin response to thyrotropin-releasing hormone in depressed and nondepressed alcoholic men. (1990 Jan 1)Willenbring MLBiol Psychiatry
27197464[Distant metastases to maxillary sinus from an unknown lung adenocarcinoma: a cases report]. (2016 Jan)Liang WLin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
26359072[The prognostic impact of preoperative PET-CT on postoperative recurrence for completely resected stage I non-small cell lung cancer]. (2015 Jul 1)Qiang GZhonghua Wai Ke Za Zhi
3918806Associations of resting heart rate with concentrations of lipoprotein subfractions in sedentary men. (1985 Mar)Williams PTCirculation
18536982Enhanced dopamine D2 receptor function in hypothalamus and corpus striatum: their role in liver, plasma and in vitro hepatocyte ALDH regulation in ethanol treated rats. (2008 Sep)Akash KGJ Biomed Sci
15846468Pharmacodynamic assessment of the benztropine analogues AHN-1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling. (2005 Apr)Raje SPharm Res
24535381Risk factors for mediastinal lymph node metastasis in non-small-cell lung cancer by PET/CT. (2014 May)Xu ZQNucl Med Commun
261029186A.03: THE RELATIONSHIP BETWEEN INTER-ARM SYSTOLIC BLOOD PRESSURE AND CARDIOVASCULAR RISK FACTORS. (2015 Jun)Ma WJ Hypertens
20541383Global muscle dysfunction as a risk factor of readmission to hospital due to COPD exacerbations. (2010 Dec)Vilaro JRespir Med
21618155Concurrent training and pulmonary function in smokers. (2011 Oct)Shaw IInt J Sports Med
12167564N-glucuronidation of nicotine and cotinine in human: formation of cotinine glucuronide in liver microsomes and lack of catalysis by 10 examined UDP-glucuronosyltransferases. (2002 Sep)Ghosheh ODrug Metab Dispos
25739534Significant Association between Serum Monokine Induced by Gamma Interferon and Carotid Intima Media Thickness. (2015 Aug 26)Yu HTJ Atheroscler Thromb
16076937Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties. (2005 Nov)Mathews JLJ Pharmacol Exp Ther
19699477Cardiovascular risk factors and non-invasive assessment of subclinical atherosclerosis in youth. (2010 Feb)Morrison KMAtherosclerosis
29101463A drug-drug interaction study to assess the effect of the CYP1A2 inhibitor fluvoxamine on the pharmacokinetics of dovitinib (TKI258) in patients with advanced solid tumors. (2018 Jan)de Weger VACancer Chemother Pharmacol
10980326Serotonin transporter gene regulatory region polymorphism (5-HTTLPR), [3H]paroxetine binding in healthy control subjects and alcohol-dependent patients and their relationships to impulsivity. (2000 Sep 25)Preuss UWPsychiatry Res
16713586Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans. (2007 Jan 1)Beuten JBiol Psychiatry
29299071Lung function discordance in monozygotic twins and associated differences in blood DNA methylation. (2017)Bolund ACSClin Epigenetics
17307646Chronic ethanol consumption increases dopamine uptake in the nucleus accumbens of high alcohol drinking rats. (2006 Oct)Carroll MRAlcohol
22429255Understanding naltrexone mechanism of action and pharmacogenetics in Asian Americans via behavioral economics: a preliminary study. (2012 Jun)Bujarski SExp Clin Psychopharmacol
9789796Pre-exercise acidification induced by ingestion of NH4Cl increases the magnitude of the slow component of VO2 kinetics in humans. (1998 Sep)Zoladz JJ Physiol Pharmacol
1831892[Cutaneous microvascular flow studied by laser-Doppler. A study of 100 healthy volunteers]. (1991 Jul 6-13)Maurel APresse Med
17955229Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine. (2008 Jan)Backman JTEur J Clin Pharmacol
7618172Exposure to complex mixtures: implications for biological monitoring. (1995 May)Ikeda MToxicol Lett
21295853In vitro and ex vivo autoradiography of the NK-1 antagonist [(3)H]-LY686017 in Guinea pig brain. (2011 Apr)Gackenheimer SLNeuropeptides
28382891Longitudinal study of diet quality and change in asthma symptoms in adults, according to smoking status. (2017 Feb)Li ZBr J Nutr
25015174A population pharmacokinetic and pharmacodynamic modelling approach to support the clinical development of RBP-6000, a new, subcutaneously injectable, long-acting, sustained-release formulation of buprenorphine, for the treatment of opioid dependence. (2014 Sep)Nasser AFClin Pharmacokinet
24692236Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders. (2014 Jun)Kos MZAm J Med Genet B Neuropsychiatr Genet
18008023Decreased expression of transporters reduces folate uptake across renal absorptive surfaces in experimental alcoholism. (2007 Dec)Hamid AJ Membr Biol
24920292Plasma irisin levels progressively increase in response to increasing exercise workloads in young, healthy, active subjects. (2014 Sep)Daskalopoulou SSEur J Endocrinol
26069112Association between Fibrinogen and Carotid Atherosclerosis According to Smoking Status in a Korean Male Population. (2015 Jul)Cho HMYonsei Med J
16113996Purification and characterization of rat liver enzyme catalyzing stereoselective reduction of acetylpyridines. (2005 Oct)Uwai KChirality
28204989Assessment of noninvasive predictors of bladder detrusor underactivity in BPH/LUTs patients. (2017 May)Luo FInt Urol Nephrol
24149634Association of cardiorespiratory fitness with elevated hepatic enzyme and liver fat in Japanese patients with impaired glucose tolerance and type 2 diabetes mellitus. (2010)Nagano MJ Sports Sci Med
29159706Alcoholism Detection by Data Augmentation and Convolutional Neural Network with Stochastic Pooling. (2017 Nov 17)Wang SHJ Med Syst
26746627Effects of paediatric HIV infection on childhood vasculature. (2016 Dec 21)Idris NSEur Heart J
11181904Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants. (2001 Mar)Brown JMJ Pharmacol Exp Ther
21824140Decreased alpha4beta2 nicotinic receptor number in the absence of mRNA changes suggests post-transcriptional regulation in the spontaneously hypertensive rat model of ADHD. (2011 Oct)Wigestrand MBJ Neurochem
28128572[Genetic determination of dyslipidemia - What tell us the results of genome-wide association studies?] (Fall 2016)Hubacek JAVnitr Lek
19216085Role of diffusion-weighted magnetic resonance imaging for predicting of tumor invasiveness for clinical stage IA non-small cell lung cancer. (2009 Apr)Kanauchi NEur J Cardiothorac Surg
9756252Body fatness: longitudinal relationship of body mass index and the sum of skinfolds with other risk factors for coronary heart disease. (1998 Sep)Twisk JWInt J Obes Relat Metab Disord
26802129Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo. (2016 Apr)Gufford BTDrug Metab Dispos
11116349Internal exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDDs/PCDFs) of Bavarian chimney sweeps. (2001 Jan)Wrbitzky RArch Environ Contam Toxicol
26527205Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects. (2016 Mar)Minakuchi HSleep Breath
16164571Levels of homocysteine are inversely associated with cardiovascular fitness in women, but not in men: data from the National Health and Nutrition Examination Survey 1999-2002. (2005 Oct)Kuo HKJ Intern Med
15947301Survival of chronic hypercapnic COPD patients is predicted by smoking habits, comorbidity, and hypoxemia. (2005 Jun)Nizet TAChest
21033140[Distribution characteristics and risk factors of carotid atherosclerosis in middle-aged and elderly Chinese]. (2010 Jun)Wang WZhonghua Xin Xue Guan Bing Za Zhi
16451640A genome-wide scanning and fine mapping study of COGA data. (2005 Dec 30)Yang HCBMC Genet
14966476Upregulation of CB1 receptors and agonist-stimulated [35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims. (2004 Feb)Hungund BLMol Psychiatry
19002702Performance and thermoregulatory effects of chronic bupropion administration in the heat. (2009 Feb)Roelands BEur J Appl Physiol
7812245Lead in bone from south Moravian autopsies. (1994 Jun)Kotulan JCent Eur J Public Health
20352174Physical demands at work, physical fitness, and 30-year ischaemic heart disease and all-cause mortality in the Copenhagen Male Study. (2010 Sep)Holtermann AScand J Work Environ Health
18329002Bakuchiol analogs inhibit monoamine transporters and regulate monoaminergic functions. (2008 May 1)Zhao GBiochem Pharmacol
10235417Pantoprazole lacks induction of CYP1A2 activity in man. (1999 Apr)Hartmann MInt J Clin Pharmacol Ther
21366359Duloxetine: clinical pharmacokinetics and drug interactions. (2011 May)Knadler MPClin Pharmacokinet
25735992Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies. (2015 Apr)Salih HJ Psychopharmacol
17624258Evaluation of tumor necrosis factor-alpha and granulocyte colony-stimulating factor serum levels in lead-exposed smoker workers. (2007 Apr-Jun)Di Lorenzo LInt J Immunopathol Pharmacol
22138144Dietary fat, abdominal obesity and smoking modulate the relationship between plasma complement component 3 concentrations and metabolic syndrome risk. (2012 Feb)Phillips CMAtherosclerosis
25987401Effects of outpatient followed by home-based telemonitored cardiac rehabilitation in patients with coronary artery disease. (2015)Szalewska DKardiol Pol
15317832Lack of pharmacokinetic interactions between cilomilast and theophylline or smoking in healthy volunteers. (2004 Sep)Murdoch RDJ Clin Pharmacol
23840486Impact of cardiovascular calcifications on the detrimental effect of continued smoking on cardiovascular risk in male lung cancer screening participants. (2013)Jairam PMPLoS One
18477263Acute passive cigarette smoke exposure and inhaled human insulin (Exubera) pharmacokinetics. (2008 Jun)Fountaine RBr J Clin Pharmacol
2083204Cardiovascular responses to exercise in essential hypertension. (1990 Oct-Dec)Balogun MOWest Afr J Med
27993294The effect of habitual waterpipe tobacco smoking on pulmonary function and exercise capacity in young healthy males: A pilot study. (2017 Jan)Hawari FIRespir Med
19710201Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model. (2010 Jan)Rivera-Meza MFASEB J
28526258Sleep duration and the associated cardiometabolic risk scores in adults. (2017 Jun)Kanagasabai TSleep Health
8591101Evaluation of the effects of various factors on the serum alpha hydroxybutyrate dehydrogenase activity in young females. (1995 Nov)Imaki MAppl Human Sci
11923696Carotid intima media thickness decreases after pancreas transplantation. (2002 Mar 27)Larsen JLTransplantation
22565239Safety and feasibility of regadenoson use for suboptimal heart rate response during symptom-limited standard Bruce exercise stress test. (2012 Oct)Partington SLJ Nucl Cardiol
23212563Coexistence of passive and proton antiporter-mediated processes in nicotine transport at the mouse blood-brain barrier. (2013 Apr)Cisternino SAAPS J
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