Gene: MCM4

4173
CDC21|CDC54|IMD54|NKCD|NKGCD|P1-CDC21|hCdc21
minichromosome maintenance complex component 4
protein-coding
8q11.21
Ensembl:ENSG00000104738 MIM:602638 Vega:OTTHUMG00000164205 UniprotKB:P33991
NG_032967.1
PubMed
0   ANCO-SNPs
ND
3   
1.109e-1 (AD)  9.027e-1 (ND)   (Frontal_Cortex)
7.176e-1 (AD)  1.036e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KLHL420.947
FAM161B0.945
RNMT0.945
MSH20.943
SLC35B40.943
GPRASP10.943
ATL10.939
DZIP30.938
ATRN0.936
GPRASP20.936

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CSAG1-0.501
MTRNR2L6-0.497
MTRNR2L9-0.485
MTRNR2L10-0.48
OR4F5-0.473
HEY2-0.448
RAI14-0.446
MTRNR2L8-0.438
PGF-0.436
PPBP-0.431

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of MCM4 mRNA"23626729
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of MCM4 mRNA"22698814|2890350
C4901661-(4-methoxyphenyl)piperazine1-(4-methoxyphenyl)piperazine results in increased expression of MCM4 mRNA26821219
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[PIK3CA gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased expression of MCM4 mRNA"20453058
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of MCM4 mRNA"25510870
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM4 mRNA"19167446
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of MCM4 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of MCM4 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of MCM4 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of MCM4 mRNA"25510870
C517041(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)"(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in decreased expression of MCM4 mRNA"19561079
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of MCM4 mRNA12419474
D000082AcetaminophenAcetaminophen results in increased expression of MCM4 mRNA22230336
D020106AcrylamideAcrylamide results in decreased expression of MCM4 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of MCM4 mRNA22100608
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of MCM4 mRNA19770486
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of MCM4 mRNA"22863853
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of MCM4 mRNA24449571
C006632arsenic trioxidearsenic trioxide results in increased expression of MCM4 mRNA20458559
C006632arsenic trioxidearsenic trioxide results in increased expression of MCM4 protein19364129|2541905
C015001arsenitearsenite affects the expression of MCM4 mRNA22959463
D001205Ascorbic Acid[Quercetin co-treated with Ascorbic Acid] results in increased expression of MCM4 mRNA17639512
D001285AtropineAtropine results in increased expression of MCM4 mRNA17390078
D001285Atropine[Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA17390078
D001379AzathioprineAzathioprine results in decreased expression of MCM4 mRNA22623647
C547126AZM551248AZM551248 results in increased expression of MCM4 mRNA22323515
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of MCM4 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of MCM4 mRNA21632981|2180250
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MCM4 mRNA"20382639
D004958Estradiol[Estradiol co-treated with EGF protein] results in increased expression of MCM4 mRNA24758408
D004958EstradiolEstradiol results in increased expression of MCM4 mRNA24758408
D004958EstradiolTamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of MCM4 mRNA]24758408
D004958EstradiolTamoxifen inhibits the reaction [Estradiol results in increased expression of MCM4 mRNA]24758408
D004958EstradiolEstradiol affects the expression of MCM4 mRNA15598610
D004958Estradiol[Progesterone co-treated with Estradiol] results in decreased expression of MCM4 protein16966611
D001622BetaineBetaine results in decreased expression of MCM4 mRNA26391144
C551172bis-N,N-dimethylamino-2-(N-methylpyrrolyl)methyl cyclopentadienyl titanium (IV)"bis-N,N-dimethylamino-2-(N-methylpyrrolyl)methyl cyclopentadienyl titanium (IV) results in decreased expression of MCM4 mRNA"20162321
C006780bisphenol Abisphenol A affects the expression of MCM4 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of MCM4 mRNA29027980
C006780bisphenol Abisphenol A results in decreased expression of MCM4 mRNA29275510
C006780bisphenol Abisphenol A affects the expression of MCM4 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of MCM4 mRNA25181051
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased phosphorylation of MCM4 protein22174045
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of MCM4 mRNA12419474
D002104CadmiumCadmium results in decreased expression of MCM4 mRNA21120746
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of MCM4 protein24527689
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of MCM4 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of MCM4 mRNA27339419
C018021cobaltous chloridecobaltous chloride results in decreased expression of MCM4 mRNA19320972|1937684
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of MCM4 mRNA20971185
D003300CopperCopper results in increased expression of MCM4 mRNA22465980
D003345CorticosteroneCorticosterone results in decreased expression of MCM4 mRNA15755911
C030123coumarincoumarin results in increased expression of MCM4 mRNA18480146
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM4 mRNA"19167446
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of MCM4 mRNA19167446
D003375CoumestrolCoumestrol results in increased expression of MCM4 mRNA19167446
C030973cupric oxidecupric oxide results in decreased expression of MCM4 mRNA22077320
D016572CyclosporineCyclosporine results in decreased expression of MCM4 mRNA19159671|2010694
D003634DDTDDT results in decreased expression of MCM4 mRNA25014179
C014347decitabinedecitabine affects the methylation of MCM4 gene17630775
D003703DemecolcineDemecolcine results in decreased expression of MCM4 mRNA23649840
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of MCM4 mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of MCM4 mRNA21266533
D002945CisplatinCisplatin inhibits the reaction [Piroxicam results in decreased expression of MCM4 mRNA]21858171
D004041Dietary FatsDietary Fats results in increased expression of MCM4 mRNA18042831
C014476diethyl maleatediethyl maleate results in increased expression of MCM4 mRNA21161181
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of MCM4 mRNA17854601
D004052DiethylnitrosamineRB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM4 mRNA]17854601
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of MCM4 mRNA19041683
D002117CalcitriolCalcitriol results in decreased expression of MCM4 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of MCM4 mRNA21592394
C024629dimethyl phthalatedimethyl phthalate affects the expression of MCM4 mRNA26924002
D004147DioxinsDioxins affects the expression of MCM4 mRNA20463971
D004317DoxorubicinDoxorubicin affects the expression of MCM4 mRNA15205334
D060754EquolEquol results in decreased expression of MCM4 mRNA16865672
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of MCM4 mRNA17555576
D005472FluorouracilFluorouracil affects the expression of MCM4 mRNA15205334
D005557FormaldehydeFormaldehyde results in decreased expression of MCM4 mRNA23649840
C039281furanfuran results in increased expression of MCM4 mRNA22079235
C001277geldanamycingeldanamycin results in increased expression of MCM4 mRNA26705709
D019833GenisteinGenistein affects the expression of MCM4 mRNA18214933
C014026hexamethylene bisacetamidehexamethylene bisacetamide results in decreased expression of MCM4 mRNA26941288
D017313FenretinideFenretinide results in increased expression of MCM4 mRNA28973697
D006851Hydrochloric AcidHydrochloric Acid results in increased expression of MCM4 mRNA15046208
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of MCM4 mRNA12419474
C492448ICG 001ICG 001 results in decreased expression of MCM4 mRNA26191083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MCM4 mRNA25613284
C051890irinotecanirinotecan metabolite results in decreased expression of MCM4 mRNA15956246
C051890irinotecanirinotecan results in decreased expression of MCM4 mRNA15956246
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of MCM4 mRNA27081696
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of MCM4 mRNA26941288
C410337K 7174K 7174 results in decreased expression of MCM4 mRNA24086573
D007854LeadLead results in decreased expression of MCM4 mRNA19921347
D018021Lithium ChlorideLithium Chloride results in decreased expression of MCM4 mRNA17440966
D008345ManganeseManganese results in decreased expression of MCM4 mRNA17175027
C025340manganese chloridemanganese chloride results in decreased expression of MCM4 mRNA17175027
D008713MethimazoleMethimazole results in decreased expression of MCM4 mRNA17403546
D008748MethylcholanthreneMethylcholanthrene results in increased expression of MCM4 mRNA20713471
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of MCM4 mRNA28001369
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in decreased expression of MCM4 mRNA12634122
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of MCM4 mRNA24810058
C517284monomethyl phthalatemonomethyl phthalate affects the expression of MCM4 mRNA26924002
C523799MRK 003MRK 003 results in decreased expression of MCM4 protein19318552
D009151Mustard GasMustard Gas results in decreased expression of MCM4 mRNA25102026
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of MCM4 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of MCM4 mRNA"25554681
C017096n-butoxyethanoln-butoxyethanol results in increased expression of MCM4 mRNA19812364
C022838nickel chloridenickel chloride results in increased expression of MCM4 mRNA24612858
C022838nickel chloridenickel chloride results in decreased expression of MCM4 mRNA17312168
C012655nimesulidenimesulide results in increased expression of MCM4 mRNA24136188
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of MCM4 mRNA20971185
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of MCM4 mRNA25729387
C030110oxaliplatinoxaliplatin results in decreased expression of MCM4 mRNA25729387
D010100OxygenOxygen deficiency results in decreased expression of MCM4 mRNA17175027|2651600
D000073878Palm OilPalm Oil results in increased expression of MCM4 mRNA18042831
D010278Parathion[Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA17390078
D010278ParathionParathion results in increased expression of MCM4 mRNA17390078
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of MCM4 mRNA"25510870
D010416PentachlorophenolPentachlorophenol results in increased expression of MCM4 mRNA23892564
C494474perchlorateperchlorate results in decreased expression of MCM4 mRNA17403546
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of MCM4 protein26879310
D010634PhenobarbitalPhenobarbital results in increased expression of MCM4 mRNA19136022|1936314
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MCM4 mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of MCM4 mRNA17950772|1830175
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in increased expression of MCM4 mRNA]17950772
D010894PiroxicamCisplatin inhibits the reaction [Piroxicam results in decreased expression of MCM4 mRNA]21858171
D010894PiroxicamPiroxicam results in decreased expression of MCM4 mRNA21858171
D011285Pregnenolone Carbonitrile"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of MCM4 mRNA"23626729
D011374ProgesteroneProgesterone results in decreased expression of MCM4 mRNA23012394
D011374Progesterone[Progesterone co-treated with Estradiol] results in decreased expression of MCM4 protein16966611
D011374ProgesteroneProgesterone results in decreased expression of MCM4 mRNA16966611
D011441PropylthiouracilPropylthiouracil results in decreased expression of MCM4 mRNA17403546
D011794Quercetin[Quercetin co-treated with Ascorbic Acid] results in increased expression of MCM4 mRNA17639512
D011794QuercetinQuercetin results in decreased expression of MCM4 mRNA23727915
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of MCM4 mRNA19167446
C059514resveratrolresveratrol results in decreased expression of MCM4 mRNA15767336
D012402RotenoneRotenone results in increased expression of MCM4 mRNA19013527
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of MCM4 mRNA23806026
D012835Silver NitrateSilver Nitrate results in increased expression of MCM4 mRNA22831968
D019821SimvastatinSimvastatin results in decreased expression of MCM4 mRNA17428261
C017947sodium arsenitesodium arsenite results in increased expression of MCM4 mRNA28595984
C016104sodium bichromatesodium bichromate results in increased expression of MCM4 mRNA24612858
C016104sodium bichromatesodium bichromate affects the expression of MCM4 mRNA22110744
C016104sodium bichromatesodium bichromate results in increased expression of MCM4 mRNA25993096
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in increased expression of MCM4 mRNA"26680231
D013629TamoxifenTamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of MCM4 mRNA]24758408
D013629TamoxifenTamoxifen inhibits the reaction [Estradiol results in increased expression of MCM4 mRNA]24758408
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of MCM4 mRNA21592394
D013739TestosteroneTestosterone results in decreased expression of MCM4 mRNA21592394
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of MCM4 mRNA21802500
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of MCM4 mRNA21570461|2637764
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of MCM4 mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of MCM4 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of MCM4 mRNA21215274
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MCM4 mRNA25613284
D019284ThapsigarginThapsigargin results in decreased expression of MCM4 mRNA22378314
D013853ThioacetamideThioacetamide results in increased expression of MCM4 mRNA23411599
C009495titanium dioxidetitanium dioxide results in increased expression of MCM4 mRNA23557971
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of MCM4 mRNA25729387
D019772TopotecanTopotecan results in decreased expression of MCM4 mRNA25729387
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in decreased expression of MCM4 mRNA"17951470
D014212TretinoinTretinoin results in decreased expression of MCM4 mRNA21934132
C012589trichostatin Atrichostatin A results in decreased expression of MCM4 mRNA23770000
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of MCM4 mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of MCM4 mRNA"26179874
C057693troglitazonetroglitazone results in decreased expression of MCM4 mRNA19140230
D014415TunicamycinTunicamycin results in decreased expression of MCM4 mRNA22378314
D014520UrethaneUrethane results in decreased expression of MCM4 mRNA28818685
D014635Valproic AcidValproic Acid results in decreased expression of MCM4 mRNA28001369
D014640VancomycinVancomycin results in decreased expression of MCM4 mRNA18930951
D001335Vehicle EmissionsVehicle Emissions affects the methylation of MCM4 gene25560391
D014750VincristineVincristine results in decreased expression of MCM4 mRNA23649840
C029297vinylidene chloridevinylidene chloride results in increased expression of MCM4 mRNA26682919
D015032ZincZinc deficiency results in increased expression of MCM4 mRNA22171008
C088658zoledronic acidzoledronic acid results in increased expression of MCM4 mRNA20977926

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003697single-stranded DNA binding-IEA-  
GO:0004003ATP-dependent DNA helicase activitycontributes_toIDA9305914  
GO:0005515protein binding-IPI12364596  15232106  16899510  16902406  17296731  22190034  
22540012  23764002  24299456  24407287  25036637  26496610  
GO:0005524ATP binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000082G1/S transition of mitotic cell cycle-TAS-  
GO:0006260DNA replication-NAS9465298  
GO:0006260DNA replication-TAS-  
GO:0006268DNA unwinding involved in DNA replication-IEA-  
GO:0006270DNA replication initiation-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000784nuclear chromosome, telomeric region-HDA19135898  
GO:0005634nucleus-NAS8265339  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0016020membrane-HDA19946888  
GO:0042555MCM complex-IDA17296731  
KEGG ID KEGG Term
hsa03030DNA replication
hsa04110Cell cycle
Reactome ID Reactome Term Evidence
R-HSA-1640170Cell CycleTAS
R-HSA-1640170Cell CycleIEA
R-HSA-176187Activation of ATR in response to replication stressTAS
R-HSA-176974Unwinding of DNAIEA
R-HSA-453279Mitotic G1-G1/S phasesTAS
R-HSA-68867Assembly of the pre-replicative complexTAS
R-HSA-68874M/G1 TransitionTAS
R-HSA-68949Orc1 removal from chromatinTAS
R-HSA-68962Activation of the pre-replicative complexTAS
R-HSA-69002DNA Replication Pre-InitiationTAS
R-HSA-69052Switching of origins to a post-replicative stateTAS
R-HSA-69190DNA strand elongationIEA
R-HSA-69206G1/S TransitionTAS
R-HSA-69239Synthesis of DNATAS
R-HSA-69239Synthesis of DNAIEA
R-HSA-69242S PhaseTAS
R-HSA-69242S PhaseIEA
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-69278Cell Cycle, MitoticIEA
R-HSA-69306DNA ReplicationTAS
R-HSA-69306DNA ReplicationIEA
R-HSA-69481G2/M CheckpointsTAS
R-HSA-69620Cell Cycle CheckpointsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27350734Relationships between cell cycle pathway gene polymorphisms and risk of hepatocellular carcinoma. (2016 Jun 28)Nan YLWorld J Gastroenterol
29135113Minichromosome maintenance (MCM) protein 4 overexpression is a potential prognostic marker for laryngeal squamous cell carcinoma. (2017 Sep-Oct)Han JJ BUON
20884074Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer. (2011 May)Kikuchi JLung Cancer