Gene: MCM7

4176
CDC47|MCM2|P1.1-MCM3|P1CDC47|P85MCM|PNAS146|PPP1R104
minichromosome maintenance complex component 7
protein-coding
7q22.1
Ensembl:ENSG00000166508 MIM:600592 Vega:OTTHUMG00000154671 UniprotKB:P33993
NC_000007.14
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.779e-1 (AD)  8.779e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KIF1C0.947
FBXW40.931
SEPT40.918
MBP0.918
FOXO40.914
BCAS10.911
LPAR10.902
CENPB0.9
PTP4A20.886
PAQR60.885

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PCDH8-0.45
CUX2-0.449
MED12L-0.446
CNTN5-0.434
HS6ST3-0.43
OR4F29-0.428
CNGB1-0.426
HCN4-0.421
KCNG3-0.42
EPHA6-0.414

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of MCM7 mRNA"22698814
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the expression of MCM7 mRNA14516785
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the expression of MCM7 protein14516785
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in increased expression of MCM7 mRNA"19114083
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM7 mRNA"19167446
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of MCM7 mRNA"21346803
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MCM7 mRNA"16120219
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MCM7 protein"16120219
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of MCM7 mRNA"21346803
C0326424-aminophenylarsenoxide4-aminophenylarsenoxide binds to MCM7 protein26598702
C0326424-aminophenylarsenoxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MCM7 protein]26598702
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of MCM7 protein22230336
D000082AcetaminophenAcetaminophen affects the expression of MCM7 mRNA17562736
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of MCM7 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of MCM7 mRNA]17585979
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of MCM7 mRNA22100608
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of MCM7 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of MCM7 mRNA19770486
C006632arsenic trioxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to MCM7 protein]26598702
C006632arsenic trioxidearsenic trioxide results in decreased expression of MCM7 mRNA26705709
C006632arsenic trioxidearsenic trioxide results in increased expression of MCM7 protein19364129
D001280AtrazineAtrazine results in increased expression of MCM7 mRNA25929836
C028559bathocuproine sulfonatebathocuproine sulfonate results in decreased expression of MCM7 mRNA16973896
C487081belinostatbelinostat results in decreased expression of MCM7 mRNA19606018
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of MCM7 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of MCM7 mRNA16120219|2006483
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of MCM7 protein20097212
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of MCM7 mRNA19770486|2234223
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MCM7 mRNA"20382639
D004958Estradiol[Estradiol co-treated with EGF protein] results in increased expression of MCM7 mRNA24758408
D004958EstradiolEstradiol results in increased expression of MCM7 mRNA16474171|1916744
D004958EstradiolTamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of MCM7 mRNA]24758408
D004958EstradiolTamoxifen inhibits the reaction [Estradiol results in increased expression of MCM7 mRNA]24758408
D004958EstradiolEstradiol inhibits the reaction [Progesterone affects the localization of MCM7 protein]16966611
D001622BetaineBetaine results in decreased expression of MCM7 mRNA26391144
C044887beta-methylcholinebeta-methylcholine affects the expression of MCM7 mRNA21179406
C006780bisphenol Abisphenol A results in decreased expression of MCM7 mRNA29275510
C006780bisphenol Abisphenol A results in increased expression of MCM7 mRNA16474171
C006780bisphenol Abisphenol A affects the expression of MCM7 mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of MCM7 mRNA26982218
D000069286BortezomibBortezomib results in decreased expression of MCM7 mRNA17659339
D002065BuspironeBuspirone results in decreased expression of MCM7 mRNA24136188
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of MCM7 mRNA15336504
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of MCM7 protein24527689
D002220CarbamazepineCarbamazepine affects the expression of MCM7 mRNA24752500
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of MCM7 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of MCM7 mRNA19887370|2733941
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of MCM7 protein19887370
C495817CC-8490CC-8490 results in decreased expression of MCM7 mRNA15604281
D002509CephaloridineCephaloridine results in increased expression of MCM7 mRNA18500788
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in decreased expression of MCM7 mRNA26272509
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MCM7 gene20938992
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of MCM7 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of MCM7 mRNA]17585979
C018021cobaltous chloridecobaltous chloride results in decreased expression of MCM7 mRNA19376846
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of MCM7 mRNA20971185
D003300CopperCopper results in increased expression of MCM7 mRNA22465980
D003345CorticosteroneCorticosterone results in decreased expression of MCM7 mRNA15755911
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM7 mRNA"19167446
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of MCM7 mRNA19167446
D003375CoumestrolCoumestrol results in increased expression of MCM7 mRNA19167446
C408982CPG-oligonucleotideCPG-oligonucleotide results in increased expression of MCM7 protein17727805
C024015cryptolepinecryptolepine results in decreased expression of MCM7 mRNA16120219
D003471CuprizoneCuprizone results in increased expression of MCM7 mRNA26577399
D003474CurcuminCurcumin results in decreased expression of MCM7 mRNA17198877
D016572CyclosporineCyclosporine results in decreased expression of MCM7 mRNA20106945|2163298
D000069439DasatinibDasatinib results in decreased expression of MCM7 mRNA20579391
C014347decitabinedecitabine affects the methylation of MCM7 gene17630775
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of MCM7 mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of MCM7 mRNA21266533
D002945CisplatinCisplatin results in increased expression of MCM7 mRNA27594783
D004008DiclofenacDiclofenac affects the expression of MCM7 mRNA24752500
D004052DiethylnitrosamineAHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of MCM7 mRNA]19996281
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of MCM7 mRNA19996281
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of MCM7 mRNA17854601
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of MCM7 protein17854601|1988737
D004052DiethylnitrosamineRB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM7 mRNA]17854601
D004052DiethylnitrosamineRB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM7 protein]17854601|1988737
D002117CalcitriolCalcitriol results in decreased expression of MCM7 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of MCM7 mRNA21592394
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in decreased expression of MCM7 mRNA27638505
C024629dimethyl phthalatedimethyl phthalate affects the expression of MCM7 mRNA26924002
D004317DoxorubicinDoxorubicin results in increased expression of MCM7 mRNA25896364
D000431EthanolEthanol affects the expression of MCM7 mRNA24355176
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of MCM7 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MCM7 mRNA17942748
D005047EtoposideEtoposide results in decreased expression of MCM7 mRNA16120219
D005472FluorouracilMCM7 protein affects the susceptibility to Fluorouracil15548681
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM7 mRNA]15016801
D005485FlutamideFlutamide results in increased expression of MCM7 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MCM7 gene20938992
D019833GenisteinGenistein results in increased expression of MCM7 mRNA16474171
C014026hexamethylene bisacetamidehexamethylene bisacetamide results in decreased expression of MCM7 mRNA26941288
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MCM7 mRNA25613284
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of MCM7 protein23430699
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of MCM7 mRNA26941288
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of MCM7 protein23430699
C410337K 7174K 7174 results in decreased expression of MCM7 mRNA24086573
C490728lapatinibERBB2 protein affects the reaction [lapatinib results in decreased expression of MCM7 protein]25221644
C490728lapatiniblapatinib results in decreased expression of MCM7 protein25221644
D007854LeadLead affects the expression of MCM7 mRNA28903495
D018021Lithium ChlorideLithium Chloride results in decreased expression of MCM7 mRNA17440966
C042720mercuric bromidemercuric bromide results in decreased expression of MCM7 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MCM7 gene20938992
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of MCM7 mRNA28001369
C008493methylselenic acidmethylselenic acid results in decreased expression of MCM7 mRNA12517777
C063855microcystin RRmicrocystin RR results in decreased expression of MCM7 protein19111056
C063855microcystin RRmicrocystin RR results in increased expression of MCM7 protein19111056
C517284monomethyl phthalatemonomethyl phthalate affects the expression of MCM7 mRNA26924002
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of MCM7 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of MCM7 mRNA"25554681
D009532NickelNickel affects the expression of MCM7 mRNA14575637
D009532Nickeltrichostatin A inhibits the reaction [Nickel affects the expression of MCM7 mRNA]14575637
C012655nimesulidenimesulide results in increased expression of MCM7 mRNA24136188
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of MCM7 mRNA20971185
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of MCM7 mRNA25729387
C030110oxaliplatinoxaliplatin results in decreased expression of MCM7 mRNA25729387
C500026palbociclibpalbociclib results in decreased expression of MCM7 mRNA22869556
C500026palbociclibpalbociclib results in decreased expression of MCM7 protein20473330
C500026palbociclibRB1 protein affects the reaction [palbociclib results in decreased expression of MCM7 protein]20473330
D010416PentachlorophenolPentachlorophenol results in increased expression of MCM7 mRNA23892564
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of MCM7 mRNA23427857
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in decreased expression of MCM7 mRNA26678675
D010634PhenobarbitalPhenobarbital affects the expression of MCM7 mRNA19159669
D010634PhenobarbitalPhenobarbital results in increased expression of MCM7 mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MCM7 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of MCM7 mRNA26272509
C006253pirinixic acid[pirinixic acid co-treated with PPARA] results in increased expression of MCM7 mRNA20813756
C006253pirinixic acidpirinixic acid results in increased expression of MCM7 mRNA17426115|1795077
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in increased expression of MCM7 mRNA]17950772
D010936Plant ExtractsPlant Extracts results in increased expression of MCM7 mRNA23557933
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls analog results in increased expression of MCM7 mRNA16474171
D011192Potassium DichromatePotassium Dichromate results in decreased expression of MCM7 mRNA11678601
D011374ProgesteroneEstradiol inhibits the reaction [Progesterone affects the localization of MCM7 protein]16966611
D011374ProgesteroneProgesterone affects the localization of MCM7 protein16966611
C005556propionaldehydepropionaldehyde results in decreased expression of MCM7 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in increased expression of MCM7 mRNA24780913
D011794QuercetinQuercetin results in decreased expression of MCM7 mRNA23727915
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of MCM7 mRNA19167446
D012643SeleniumSelenium results in increased expression of MCM7 mRNA19244175
C009250sevofluranesevoflurane results in increased expression of MCM7 mRNA26206149
D012822Silicon DioxideSilicon Dioxide results in decreased expression of MCM7 mRNA25351596
D012839SimazineSimazine results in decreased expression of MCM7 mRNA25461544
D020123SirolimusSirolimus inhibits the reaction [IL2 protein results in increased expression of MCM7 mRNA]11355896
C017947sodium arsenitesodium arsenite results in decreased expression of MCM7 mRNA12760830|2451658
C017947sodium arsenitesodium arsenite results in decreased expression of MCM7 mRNA16014739
C016104sodium bichromatesodium bichromate affects the expression of MCM7 mRNA22110744
C016104sodium bichromatesodium bichromate results in increased expression of MCM7 mRNA25993096
D053260SootSoot results in increased expression of MCM7 mRNA26551751
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in increased expression of MCM7 mRNA"26680231
D013605T-2 ToxinT-2 Toxin affects the expression of MCM7 protein26141394
D013629TamoxifenTamoxifen inhibits the reaction [[Estradiol co-treated with EGF protein] results in increased expression of MCM7 mRNA]24758408
D013629TamoxifenTamoxifen inhibits the reaction [Estradiol results in increased expression of MCM7 mRNA]24758408
D013629TamoxifenTamoxifen results in decreased expression of MCM7 mRNA15604281
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of MCM7 mRNA21592394
D013739TestosteroneTestosterone results in decreased expression of MCM7 mRNA21592394
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of MCM7 mRNA22574217
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of MCM7 mRNA21802500
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of MCM7 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MCM7 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of MCM7 mRNA16611356
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of MCM7 mRNA15667827
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MCM7 mRNA25613284
D019284ThapsigarginThapsigargin results in increased expression of MCM7 mRNA19442820
C009495titanium dioxidetitanium dioxide results in increased expression of MCM7 mRNA23557971
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of MCM7 mRNA25729387
D019772TopotecanTopotecan results in decreased expression of MCM7 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of MCM7 mRNA"19682533
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in decreased expression of MCM7 mRNA"17951470
D014212TretinoinTretinoin results in decreased expression of MCM7 mRNA16249480
C012589trichostatin Atrichostatin A affects the expression of MCM7 mRNA28542535
C012589trichostatin Atrichostatin A inhibits the reaction [Nickel affects the expression of MCM7 mRNA]14575637
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of MCM7 mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of MCM7 mRNA"26179874
C057693troglitazonetroglitazone results in decreased expression of MCM7 mRNA19140230
C057693troglitazonetroglitazone results in decreased expression of MCM7 mRNA28973697
D014520UrethaneUrethane results in decreased expression of MCM7 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of MCM7 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of MCM7 mRNA23179753|2718838
D014640VancomycinVancomycin results in decreased expression of MCM7 mRNA18930951
D014800VitalliumVitallium analog results in decreased expression of MCM7 mRNA23825117

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003677DNA bindingcontributes_toTAS15538388  
GO:0003697single-stranded DNA binding-IEA-  
GO:0004003ATP-dependent DNA helicase activitycontributes_toIDA9305914  
GO:0005515protein binding-IPI9705868  10518787  12364596  14675634  14743216  15232106  
15538388  15654075  16289477  16438930  16899510  17296731  
17310990  17314511  17353931  19150984  20098747  22540012  
23397142  23764002  24299456  25036637  25416956  26496610  
26871637  28191891  
GO:0005524ATP binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000082G1/S transition of mitotic cell cycle-TAS-  
GO:0006260DNA replication-TAS-  
GO:0006268DNA unwinding involved in DNA replication-IEA-  
GO:0006270DNA replication initiation-IEA-  
GO:0006974cellular response to DNA damage stimulus-IMP15538388  
GO:0008283cell proliferation-IEA-  
GO:0042325regulation of phosphorylation-IMP15538388  
GO:0042493response to drug-IEA-  
GO:0071364cellular response to epidermal growth factor stimulus-IEA-  
GO:0071466cellular response to xenobiotic stimulus-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000784nuclear chromosome, telomeric region-HDA19135898  
GO:0000785chromatin-TAS8798650  
GO:0005634nucleus-IDA21383955  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005730nucleolusNOTIDA21383955  
GO:0005829cytosol-IDA-  
GO:0016020membrane-HDA19946888  
GO:0042555MCM complex-IDA17296731  
GO:0042555MCM complex-IMP15538388  
KEGG ID KEGG Term
hsa03030DNA replication
hsa04110Cell cycle
Reactome ID Reactome Term Evidence
R-HSA-1640170Cell CycleTAS
R-HSA-1640170Cell CycleIEA
R-HSA-176187Activation of ATR in response to replication stressTAS
R-HSA-176974Unwinding of DNAIEA
R-HSA-453279Mitotic G1-G1/S phasesTAS
R-HSA-68867Assembly of the pre-replicative complexTAS
R-HSA-68874M/G1 TransitionTAS
R-HSA-68949Orc1 removal from chromatinTAS
R-HSA-68962Activation of the pre-replicative complexTAS
R-HSA-69002DNA Replication Pre-InitiationTAS
R-HSA-69052Switching of origins to a post-replicative stateTAS
R-HSA-69190DNA strand elongationIEA
R-HSA-69206G1/S TransitionTAS
R-HSA-69239Synthesis of DNATAS
R-HSA-69239Synthesis of DNAIEA
R-HSA-69242S PhaseTAS
R-HSA-69242S PhaseIEA
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-69278Cell Cycle, MitoticIEA
R-HSA-69306DNA ReplicationTAS
R-HSA-69306DNA ReplicationIEA
R-HSA-69481G2/M CheckpointsTAS
R-HSA-69620Cell Cycle CheckpointsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29151950MCMs expression in lung cancer: implication of prognostic significance. (2017)Liu YZJ Cancer