Gene: CD99

4267
HBA71|MIC2|MIC2X|MIC2Y|MSK5X
CD99 molecule (Xg blood group)
protein-coding
Xp22.33 and Yp11.2
Ensembl:ENSG00000002586 MIM:450000 Vega:OTTHUMG00000021073 UniprotKB:P14209
NG_009174.1
PubMed
0   ANCO-SNPs
ND
4   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TRIP60.84
RHOC0.825
ABHD40.822
LRP100.818
PTTG1IP0.816
TMBIM10.812
NECAP20.806
AGTRAP0.806
STOM0.805
SORBS30.801

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GABRG3-0.527
PPEF1-0.521
ZNF860-0.517
ABCC12-0.515
XKR4-0.506
CALHM1-0.505
TYRP1-0.499
IL12RB2-0.487
GPR61-0.486
CHRM2-0.486

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0303702-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone"2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone results in increased expression of CD99 mRNA"20206263
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of CD99 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of CD99 mRNA19770486
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CD99 mRNA27858113
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CD99 mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of CD99 mRNA26377693
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CD99 mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CD99 mRNA19770486
C006780bisphenol Abisphenol A affects the expression of CD99 mRNA21786754
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CD99 mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of CD99 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] affects the expression of CD99 mRNA28628672
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of CD99 mRNA15336504
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CD99 mRNA27858113
D002994ClofibrateClofibrate results in decreased expression of CD99 mRNA17585979
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CD99 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] affects the expression of CD99 mRNA28628672
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CD99 mRNA21266533
D004317DoxorubicinDoxorubicin affects the expression of CD99 protein29385562
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CD99 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] affects the expression of CD99 mRNA28628672
D007213IndomethacinIndomethacin results in increased expression of CD99 mRNA28201806
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CD99 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] affects the expression of CD99 mRNA28628672
C008261lead acetatelead acetate results in decreased expression of CD99 mRNA21829687
D008727MethotrexateCD99 protein affects the susceptibility to Methotrexate16217747
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CD99 mRNA26011545
C029938nickel sulfatenickel sulfate results in increased expression of CD99 mRNA22714537
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of CD99 mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of CD99 mRNA17426115
D012643SeleniumSelenium results in increased expression of CD99 mRNA19244175
C009277sodium arsenatesodium arsenate results in decreased expression of CD99 mRNA23922661
D013849ThimerosalThimerosal results in decreased expression of CD99 mRNA27188386
C009495titanium dioxidetitanium dioxide results in decreased expression of CD99 mRNA23409001
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of CD99 mRNA24935251|2627250
D014403TubocurarineTubocurarine results in increased expression of CD99 mRNA19728367
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD99 mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of CD99 mRNA19101580|2317975
C025643vinclozolinvinclozolin affects the expression of CD99 mRNA19015723
C029297vinylidene chloridevinylidene chloride results in increased expression of CD99 mRNA26682919
D014810Vitamin EVitamin E results in increased expression of CD99 mRNA19244175

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI20374249  
GO ID GO Term Qualifier Evidence PubMed
GO:0007155cell adhesion-IEA-  
GO:0050776regulation of immune response-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-TAS2479542  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-TAS2465491  2479542  
GO:0005925focal adhesion-HDA21423176  
KEGG ID KEGG Term
hsa04514Cell adhesion molecules (CAMs)
hsa04670Leukocyte transendothelial migration
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisIEA
R-HSA-1280218Adaptive Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-198933Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellTAS
R-HSA-202733Cell surface interactions at the vascular wallIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
12968312[Solitary fibrous pseudopapillary tumor of the lung: pulmonary fibroadenoma and adenofibroma revisited]. (2003 Jun)Cavazza APathologica
26875702Synovial sarcoma presenting as a lung mass and diagnosed by cytology. (2016 May)Pyden ADDiagn Cytopathol
20450548[Clinical features of pulmonary malignancies in patients younger than 30 years of age]. (2010 Apr)Zhao JZhongguo Yi Xue Ke Xue Yuan Xue Bao
27993885Pulmonary Adenofibroma: Report of a Case with Multiple Masses. (2016 Dec)Hao JAnn Clin Lab Sci