Gene: NR3C2

4306
MCR|MLR|MR|NR3C2VIT
nuclear receptor subfamily 3 group C member 2
protein-coding
4q31.23
Ensembl:ENSG00000151623 MIM:600983 Vega:OTTHUMG00000161455 UniprotKB:P08235
NG_013350.1
PubMed|SNP Mapped
2   ANCO-SNPs
CD|OD|ND|AD
7   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.563e-1 (AD)  5.131e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs5522chr4:148436323 (GRCh38.p7)C>Tnicotine dependenceSNV(Single Nucleotide Variation)
rs5525chr4:148435364 (GRCh38.p7)A>C / A>Gnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg05437692chr4:149362435NR3C2Promoter5.141e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MAST40.896
PBX10.895
ARHGAP320.877
SMARCA20.876
ATL20.866
FAM217B0.858
CCNG20.857
RAB11FIP20.856
FOXO30.856
CACNB20.855

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.5
OR4F29-0.466
GNG8-0.449
SGMS2-0.397
C9orf135-0.391
TGFB3-0.391
HAS2-0.378
CTNNA3-0.371
FCRLA-0.368
SNHG18-0.36

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00393NimodipineSmall Molecule66085-59-4Approved|InvestigationalTarget
DB00396ProgesteroneSmall Molecule57-83-0ApprovedTarget
DB00421SpironolactoneSmall Molecule52-01-7ApprovedTarget
DB00588Fluticasone propionateSmall Molecule80474-14-2ApprovedTarget
DB00624TestosteroneSmall Molecule58-22-0Approved|InvestigationalTarget
DB00687FludrocortisoneSmall Molecule127-31-1Approved|InvestigationalTarget
DB00700EplerenoneSmall Molecule107724-20-9ApprovedTarget
DB01023FelodipineSmall Molecule72509-76-3Approved|InvestigationalTarget
DB01134Desoxycorticosterone PivalateSmall Molecule808-48-0ExperimentalTarget
DB01395DrospirenoneSmall Molecule67392-87-4ApprovedTarget
DB02901StanoloneSmall Molecule521-18-6Illicit|InvestigationalTarget
DB02998MethyltrienoloneSmall Molecule965-93-5ExperimentalTarget
DB04630AldosteroneSmall Molecule52-39-1Experimental|InvestigationalTarget
DB04652CorticosteroneSmall Molecule50-22-6ExperimentalTarget
DB06780Desoxycorticosterone acetateSmall Molecule56-47-3ApprovedTarget
DB13943Testosterone cypionateSmall Molecule58-20-8ApprovedTarget
DB13944Testosterone enanthateSmall Molecule315-37-7ApprovedTarget
DB13946Testosterone undecanoateSmall Molecule5949-44-0Approved|InvestigationalTarget
DB13951Stanolone acetateSmall Molecule1164-91-6ExperimentalTarget
ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of NR3C2 mRNA"25510870
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of NR3C2 mRNA"25565004
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of NR3C2 mRNA"19114083
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of NR3C2 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of NR3C2 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of NR3C2 mRNA"25510870
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of NR3C2 mRNA"21346803
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of NR3C2 mRNA"25510870
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in decreased expression of NR3C2 mRNA"20406850
C5847872-acetylphenothiazine2-acetylphenothiazine inhibits the reaction [anacetrapib results in increased expression of NR3C2 mRNA]25617244
C5847872-acetylphenothiazine2-acetylphenothiazine inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]25617244
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of NR3C2 mRNA25088246
C0132793,4,3',4'-tetrachloroazobenzene"3,4,3',4'-tetrachloroazobenzene binds to NR3C2 protein"26878642
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR3C2 mRNA"28973690
C1018503',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide"3',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide binds to and results in decreased activity of NR3C2 protein"16750840
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR3C2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR3C2 mRNA"27188386
C5705436-(1-(4-fluoro-2-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)-2H-1,4-benzoxazin-3(4H)-one"6-(1-(4-fluoro-2-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)-2H-1,4-benzoxazin-3(4H)-one binds to and results in decreased activity of NR3C2 protein"22074142
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR3C2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR3C2 mRNA"27188386
C0471757-propyl spirolactone7-propyl spirolactone binds to and results in decreased activity of NR3C2 protein23275455
C001969acephateacephate inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
C001969acephateacephate inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000082AcetaminophenAcetaminophen results in increased expression of NR3C2 mRNA26690555
D000082Acetaminophen[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA25607892
D000111AcetylcysteineAcetylcysteine inhibits the reaction [anacetrapib results in increased expression of NR3C2 mRNA]25617244
D000111AcetylcysteineAcetylcysteine inhibits the reaction [dalcetrapib results in increased expression of NR3C2 mRNA]25617244
D000111AcetylcysteineAcetylcysteine inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]25617244
D016604Aflatoxin B1Aflatoxin B1 affects the expression of NR3C2 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of NR3C2 mRNA27153756
C000188alachloralachlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
C000188alachloralachlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450Aldosteroneacephate inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450Aldosteroneacephate inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450Aldosteronealachlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450Aldosteronealachlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneAldosterone affects the localization of NR3C2 protein17596522|2914934
D000450AldosteroneAldosterone binds to and results in increased activity of NR3C2 protein17105867
D000450AldosteroneAldosterone binds to NR3C2 protein15362971
D000450AldosteroneAldosterone inhibits the reaction [TSG101 protein binds to NR3C2 protein]22798426
D000450AldosteroneAldosterone results in decreased expression of and affects the ubiquitination of NR3C2 protein22798426
D000450AldosteroneAldosterone results in increased activity of NR3C2 protein15362971|1578066
D000450AldosteroneAldosterone results in increased expression of NR3C2 mRNA20207834|2050828
D000450AldosteroneAldosterone results in increased expression of NR3C2 protein20508287
D000450AldosteroneAtrazine metabolite inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450AldosteroneAtrazine metabolite inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450Aldosteronebifenthrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450Aldosteronebifenthrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450Aldosteronecypermethrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450Aldosteronecypermethrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneDDT inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450AldosteroneDDT inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneDichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450AldosteroneDichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneDihydrotestosterone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]17105867
D000450AldosteroneDimethoate inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450AldosteroneDimethoate inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450Aldosteronefenvalerate inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450Aldosteronefipronil inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneMethoxychlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450AldosteroneMethoxychlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneMetribolone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]17105867
D000450Aldosterone"o,p'-DDT inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]"29149346
D000450Aldosterone"o,p'-DDT inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]"29149346
D000450AldosteronePermethrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450AldosteronePermethrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneSpironolactone inhibits the reaction [Aldosterone affects the ubiquitination of NR3C2 protein]22798426
D000450AldosteroneSpironolactone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450Aldosteroneterbutylazine inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450Aldosteroneterbutylazine inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneTestosterone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]17105867
D000450AldosteroneZineb inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D000450AldosteroneZineb inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D000450AldosteroneAldosterone affects the localization of NR3C2 protein22798426
D000450AldosteroneAldosterone inhibits the reaction [TSG101 protein binds to NR3C2 protein]22798426
D000450AldosteroneAldosterone results in decreased expression of NR3C2 protein22798426
D000450AldosteroneAldosterone results in increased phosphorylation of NR3C2 protein22798426
D000450AldosteroneFR 180204 inhibits the reaction [Aldosterone results in increased phosphorylation of NR3C2 protein]22798426
D000450AldosteroneAldosterone promotes the reaction [NR3C2 protein binds to CREBBP protein]19966502
D000450AldosteroneAldosterone results in decreased expression of NR3C2 mRNA8969928
D000450AldosteroneAldosterone results in increased activity of NR3C2 protein15974890
D000450AldosteroneAldosterone results in increased expression of and results in increased localization of NR3C2 protein19966502
D000450AldosteroneAldosterone results in increased phosphorylation of NR3C2 protein22798426
D000450AldosteroneNR3C2 protein promotes the reaction [Aldosterone results in increased expression of GAS6 protein]19564549
D000450Aldosteronetorsemide inhibits the reaction [Aldosterone binds to NR3C2 protein]7954537
D000450AldosteroneAldosterone binds to and results in increased activity of NR3C2 protein15761029|2207414
D000450AldosteroneAldosterone binds to NR3C2 protein25204689
D000450Aldosterone[Aldosterone binds to NR3C2 protein] which binds to NCOA1 protein alternative form15761029
D000450Aldosterone[Aldosterone binds to NR3C2 protein] which binds to NCOA5 protein15761029
D000450Aldosterone[Aldosterone binds to NR3C2 protein] which binds to NCOA6 protein alternative form15761029
D000450Aldosterone[Aldosterone binds to NR3C2 protein] which binds to NRIP1 protein alternative form15761029
D000450Aldosterone[Aldosterone binds to NR3C2 protein] which binds to NSD1 protein15761029
D000450Aldosterone[Aldosterone binds to NR3C2 protein] which binds to PPARGC1A protein alternative form15761029
D000450Aldosterone[Aldosterone binds to NR3C2 protein] which binds to TRIM24 protein15761029
D013196DihydrotestosteroneDihydrotestosterone binds to NR3C2 protein17105867
D013196DihydrotestosteroneDihydrotestosterone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]17105867
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of NR3C2 mRNA21298039
D000639AmitriptylineAmitriptyline results in increased expression of NR3C2 mRNA12393271
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NR3C2 mRNA16483693
C530884anacetrapib2-acetylphenothiazine inhibits the reaction [anacetrapib results in increased expression of NR3C2 mRNA]25617244
C530884anacetrapibAcetylcysteine inhibits the reaction [anacetrapib results in increased expression of NR3C2 mRNA]25617244
C530884anacetrapibanacetrapib results in increased expression of NR3C2 mRNA25617244
C530884anacetrapibGKT137831 inhibits the reaction [anacetrapib results in increased expression of NR3C2 mRNA]25617244
D000726Androgen Antagonists[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA25607892
D000806Angiotensin-Converting Enzyme InhibitorsAngiotensin-Converting Enzyme Inhibitors results in decreased expression of NR3C2 mRNA16413583
D000806Angiotensin-Converting Enzyme InhibitorsAngiotensin-Converting Enzyme Inhibitors results in decreased expression of NR3C2 protein16413583
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of NR3C2 mRNA"25351596
D001280AtrazineAtrazine metabolite inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D001280AtrazineAtrazine metabolite inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D001507BeclomethasoneBeclomethasone results in increased activity of NR3C2 protein15362971
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of NR3C2 mRNA20106945
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NR3C2 mRNA21839799
D004958EstradiolNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]23275455
D004958EstradiolNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA]23275455
D004958EstradiolNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA]23275455
D004958Estradiol[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of NR3C2 protein23275455
D001623BetamethasoneBetamethasone results in increased activity of NR3C2 protein15362971
C099952bifenthrinbifenthrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
C099952bifenthrinbifenthrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
C006780bisphenol Abisphenol A affects the expression of NR3C2 mRNA23557687
C006780bisphenol Abisphenol A inhibits the reaction [Triiodothyronine results in increased expression of NR3C2 mRNA]21684237
C006780bisphenol Abisphenol A results in increased expression of NR3C2 mRNA21684237
C006780bisphenol Abisphenol A results in increased expression of NR3C2 protein26398930
C006780bisphenol Abisphenol A affects the expression of NR3C2 mRNA24857958|2518105
C006780bisphenol A[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA25607892
C006780bisphenol Abisphenol A results in increased expression of NR3C2 mRNA26060449
C006780bisphenol Abisphenol A results in increased methylation of NR3C2 gene28505145
D001761BleomycinBleomycin results in decreased expression of NR3C2 mRNA15808516
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR3C2 mRNA22079614
D0151248-Bromo Cyclic Adenosine Monophosphate[Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA23275455
D0151248-Bromo Cyclic Adenosine Monophosphate[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA23275455
D0151248-Bromo Cyclic Adenosine Monophosphate[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 protein23275455
D0151248-Bromo Cyclic Adenosine MonophosphateNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]23275455
D0151248-Bromo Cyclic Adenosine MonophosphateNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA]23275455
D0151248-Bromo Cyclic Adenosine MonophosphateNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA]23275455
D0151248-Bromo Cyclic Adenosine Monophosphate[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of NR3C2 protein23275455
D0151248-Bromo Cyclic Adenosine Monophosphate[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA23275455
D019819BudesonideBudesonide results in increased activity of NR3C2 protein15362971
C038091butylparaben[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA25607892
D002110CaffeineCaffeine results in increased expression of NR3C2 mRNA22959462
C081643candesartancandesartan affects the expression of NR3C2 mRNA18796534
D002220CarbamazepineCarbamazepine results in increased expression of NR3C2 mRNA17112801
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of NR3C2 mRNA16644059
D002713Chlorine[Ozone co-treated with Chlorine] results in decreased expression of NR3C2 mRNA18636392
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of NR3C2 gene20938992
C018021cobaltous chloridecobaltous chloride results in decreased expression of NR3C2 mRNA19320972
D003042CocaineCocaine deficiency results in increased expression of NR3C2 mRNA22860061
D003345CorticosteroneCorticosterone binds to NR3C2 protein16061183
D003348CortisoneCortisone results in increased activity of NR3C2 protein15780662
D003471CuprizoneCuprizone results in decreased expression of NR3C2 mRNA26577399
D016572CyclosporineCyclosporine results in decreased expression of NR3C2 mRNA20106945
C017160cypermethrincypermethrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
C017160cypermethrincypermethrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
C411602dalcetrapibAcetylcysteine inhibits the reaction [dalcetrapib results in increased expression of NR3C2 mRNA]25617244
C411602dalcetrapibdalcetrapib results in increased expression of NR3C2 mRNA25617244
C411602dalcetrapibGKT137831 inhibits the reaction [dalcetrapib results in increased expression of NR3C2 mRNA]25617244
D003634DDTDDT inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D003634DDTDDT inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D003671DEET[fipronil co-treated with DEET] results in decreased expression of NR3C2 mRNA27091632
D003350CortodoxoneCortodoxone results in increased activity of NR3C2 protein15780662
D003907Dexamethasone[Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA23275455
D003907DexamethasoneDexamethasone results in increased activity of NR3C2 protein15362971
D003907DexamethasoneDexamethasone results in increased expression of NR3C2 mRNA19022236
D003907DexamethasoneDexamethasone binds to NR3C2 protein21281618
D003907DexamethasoneFluoxetine affects the reaction [Dexamethasone binds to NR3C2 protein]21281618
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D004041Dietary FatsDietary Fats results in decreased expression of NR3C2 mRNA25016146
D004117DimethoateDimethoate inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D004117DimethoateDimethoate inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
C035144drospirenonedrospirenone binds to NR3C2 protein14667981|1493716
D004656EnalaprilEnalapril results in increased expression of NR3C2 mRNA18796534
C038939enzacamene[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA25607892
C414690eplerenoneeplerenone binds to and results in decreased activity of NR3C2 protein15974890
C414690eplerenoneeplerenone binds to and results in decreased activity of NR3C2 protein15761029|1589489
C414690eplerenoneeplerenone results in decreased activity of NR3C2 protein18660453
D000431EthanolEthanol results in decreased expression of NR3C2 mRNA16925589|1867233
D000431EthanolEthanol results in increased expression of NR3C2 mRNA17920746
C017690fenvaleratefenvalerate inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
C017690fenvaleratefenvalerate affects the methylation of NR3C2 gene23548413
C082360fipronil[fipronil co-treated with DEET] results in decreased expression of NR3C2 mRNA27091632
C082360fipronilfipronil inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D005419FlavonoidsFlavonoids results in increased expression of NR3C2 mRNA18035473
C034635fludrocortisone acetatefludrocortisone acetate results in increased expression of NR3C2 mRNA23306105
D005443FlumethasoneFlumethasone results in increased activity of NR3C2 protein15362971
D005438Fludrocortisone[Fludrocortisone binds to and results in increased activity of NR3C2 protein] which results in decreased abundance of Hydrocortisone16566900
D005438Fludrocortisone[Fludrocortisone binds to and results in increased activity of NR3C2 protein] which results in decreased expression of POMC protein16566900
D005438FludrocortisoneFludrocortisone binds to and results in increased activity of NR3C2 protein16566900
D005473FluoxetineFluoxetine affects the reaction [Dexamethasone binds to NR3C2 protein]21281618
D005473FluoxetineFluoxetine results in decreased expression of NR3C2 mRNA11406320
D005473FluoxetineFluoxetine results in increased expression of NR3C2 mRNA10929085|1239327
D005473FluoxetineFluoxetine results in increased expression of NR3C2 protein10929085
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of NR3C2 gene20938992
C505241FR 180204FR 180204 inhibits the reaction [Aldosterone results in increased phosphorylation of NR3C2 protein]22798426
C576694GKT137831GKT137831 inhibits the reaction [anacetrapib results in increased expression of NR3C2 mRNA]25617244
C576694GKT137831GKT137831 inhibits the reaction [dalcetrapib results in increased expression of NR3C2 mRNA]25617244
C576694GKT137831GKT137831 inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]25617244
D006852HydrochlorothiazideHydrochlorothiazide results in increased expression of NR3C2 mRNA18796534
D006854Hydrocortisone[Fludrocortisone binds to and results in increased activity of NR3C2 protein] which results in decreased abundance of Hydrocortisone16566900
D006854HydrocortisoneHydrocortisone results in increased activity of NR3C2 protein15362971|1578066
D006854HydrocortisoneHydrocortisone binds to and affects the activity of NR3C2 protein15761029
D006854HydrocortisoneHydrocortisone results in increased activity of NR3C2 protein15199296
D003900DesoxycorticosteroneDesoxycorticosterone results in decreased expression of NR3C2 mRNA8969928
C051890irinotecanirinotecan affects the expression of NR3C2 mRNA20097248
D007657Ketone BodiesKetone Bodies results in increased expression of NR3C2 mRNA15469884
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of NR3C2 mRNA"24972896
D017258Medroxyprogesterone Acetate[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA23275455
D017258Medroxyprogesterone Acetate[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 protein23275455
C545385MequindoxMequindox results in decreased expression of NR3C2 mRNA20553828
D008713MethimazoleMethimazole results in decreased expression of NR3C2 mRNA17403546
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of NR3C2 gene20938992
D008731MethoxychlorMethoxychlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D008731MethoxychlorMethoxychlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D015741MetriboloneMetribolone binds to and results in decreased activity of NR3C2 protein17105867
D015741MetriboloneMetribolone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]17105867
D015735MifepristoneMifepristone results in increased expression of NR3C2 mRNA22475373
D009532NickelNickel results in decreased expression of NR3C2 mRNA24768652|2558310
D009538NicotineNicotine results in decreased expression of NR3C2 mRNA22975262
D009640NorethindroneNorethindrone results in increased expression of NR3C2 mRNA22475373
D016912LevonorgestrelLevonorgestrel results in increased expression of NR3C2 mRNA22475373
C118580octylmethoxycinnamate[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA25607892
C016340o,p'-DDT"o,p'-DDT inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]"29149346
C016340o,p'-DDT"o,p'-DDT inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]"29149346
D010126Ozone[Ozone co-treated with Chlorine] results in decreased expression of NR3C2 mRNA18636392
D010269ParaquatParaquat results in decreased expression of NR3C2 mRNA18198484
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of NR3C2 mRNA"25510870
C494474perchlorateperchlorate results in decreased expression of NR3C2 mRNA17403546
D026023PermethrinPermethrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D026023PermethrinPermethrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D010656PhenylephrinePhenylephrine promotes the reaction [NR3C2 protein binds to CREBBP protein]19966502
D010656PhenylephrinePhenylephrine results in increased expression of and results in increased localization of NR3C2 protein19966502
D010656PhenylephrinePhenylephrine results in increased expression of NR3C2 mRNA16533503
D010656PhenylephrineSpironolactone inhibits the reaction [Phenylephrine results in increased localization of NR3C2 protein]19966502
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR3C2 mRNA"27188386
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of NR3C2 mRNA22714537
D011192Potassium DichromatePotassium Dichromate results in increased expression of NR3C2 mRNA23608068
D011239PrednisolonePrednisolone results in increased activity of NR3C2 protein15362971
C036266prednylideneprednylidene results in increased activity of NR3C2 protein15362971
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of NR3C2 mRNA28903501
D011374ProgesteroneProgesterone results in increased expression of NR3C2 mRNA22475373
D011374ProgesteroneNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA]23275455
D011374ProgesteroneNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of DHRS3 mRNA]23275455
D011374ProgesteroneNR3C2 protein promotes the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of FBXO32 mRNA]23275455
D011374Progesterone[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of NR3C2 protein23275455
D011374Progesterone[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of NR3C2 mRNA23275455
D011374ProgesteroneProgesterone results in increased activity of NR3C2 protein15362971
D011374ProgesteroneProgesterone binds to NR3C2 protein14667981
D011374ProgesteroneProgesterone binds to and results in decreased activity of NR3C2 protein14667981|1576102
D011441PropylthiouracilPropylthiouracil results in decreased expression of NR3C2 mRNA24780913
D011441PropylthiouracilPropylthiouracil results in decreased expression of NR3C2 mRNA17403546
D012402RotenoneRotenone inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]25617244
D012822Silicon DioxideSilicon Dioxide results in increased expression of NR3C2 mRNA25351596
D012964SodiumNR3C2 protein affects the abundance of Sodium15802372|1606118
C017947sodium arsenitesodium arsenite affects the activity of NR3C2 protein17173375
D017673Sodium Chloride, Dietary"Sodium Chloride, Dietary results in increased expression of NR3C2 mRNA"18796534
D013148SpironolactoneSpironolactone inhibits the reaction [Aldosterone affects the ubiquitination of NR3C2 protein]22798426
D013148SpironolactoneSpironolactone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D013148SpironolactoneSpironolactone results in increased activity of NR3C2 protein15780662
D013148SpironolactoneSpironolactone binds to and results in decreased activity of NR3C2 protein15961248
D013148SpironolactoneSpironolactone inhibits the reaction [Phenylephrine results in increased localization of NR3C2 protein]19966502
D013148SpironolactoneSpironolactone results in decreased expression of NR3C2 mRNA17587755
D013148SpironolactoneSpironolactone results in decreased expression of NR3C2 protein19114643
D013148SpironolactoneSpironolactone binds to and results in decreased activity of NR3C2 protein17278980|2207414
D013148SpironolactoneSpironolactone results in decreased activity of NR3C2 protein18660453
D014284Triiodothyroninebisphenol A inhibits the reaction [Triiodothyronine results in increased expression of NR3C2 mRNA]21684237
D014284TriiodothyronineTriiodothyronine results in increased expression of NR3C2 mRNA21684237
D014284TriiodothyronineTriiodothyronine affects the expression of NR3C2 mRNA17403546
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid affects the reaction [APP protein modified form affects the localization of NR3C2 protein]16728529
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid binds to NR3C2 protein16728529
C031655tauroursodeoxycholic acid[tauroursodeoxycholic acid binds to NR3C2 protein] which affects the localization of NR3C2 protein16728529
C031655tauroursodeoxycholic acid[tauroursodeoxycholic acid co-treated with TGFB1 protein] results in increased localization of NR3C2 protein15222754
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid inhibits the reaction [TGFB1 protein results in decreased expression of NR3C2 mRNA]15222754
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid inhibits the reaction [TGFB1 protein results in decreased expression of NR3C2 protein]15222754
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased expression of NR3C2 mRNA15222754
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased localization of NR3C2 protein15222754
C037565terbutylazineterbutylazine inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
C037565terbutylazineterbutylazine inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346
D013739TestosteroneTestosterone binds to NR3C2 protein17105867
D013739TestosteroneTestosterone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]17105867
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of NR3C2 mRNA24058054
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of NR3C2 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NR3C2 mRNA21215274
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of NR3C2 mRNA16533503
D013853ThioacetamideThioacetamide results in increased expression of NR3C2 mRNA23411599
D013974ThyroxineThyroxine affects the expression of NR3C2 mRNA17403546
C483909torcetrapib2-acetylphenothiazine inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]25617244
C483909torcetrapibAcetylcysteine inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]25617244
C483909torcetrapibGKT137831 inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]25617244
C483909torcetrapibRotenone inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]25617244
C483909torcetrapibtorcetrapib results in increased expression of NR3C2 mRNA25617244
C026116torsemidetorsemide inhibits the reaction [Aldosterone binds to NR3C2 protein]7954537
D014221TriamcinoloneTriamcinolone results in decreased activity of NR3C2 protein15362971
D014221TriamcinoloneTriamcinolone results in increased activity of NR3C2 protein15362971
C005445triphenyl phosphatetriphenyl phosphate results in decreased expression of NR3C2 mRNA23306105
C005445triphenyl phosphatetriphenyl phosphate results in increased expression of NR3C2 mRNA26865342
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of NR3C2 mRNA"23306105
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate results in decreased expression of NR3C2 mRNA26562049
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate results in increased expression of NR3C2 mRNA26547027
C031324tris(chloroethyl)phosphatetris(chloroethyl)phosphate results in increased expression of NR3C2 mRNA27776230
C057693troglitazonetroglitazone results in decreased expression of NR3C2 mRNA28973697
D014520UrethaneUrethane results in increased expression of NR3C2 mRNA28818685
D014580Ursodeoxycholic AcidNR3C2 mutant form inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in decreased expression of MDM2 protein]]15222754
D014580Ursodeoxycholic AcidNR3C2 mutant form inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in increased expression of E2F1 protein]]15222754
D014580Ursodeoxycholic AcidNR3C2 mutant form inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]]15222754
D014580Ursodeoxycholic AcidNR3C2 mutant form inhibits the reaction [Ursodeoxycholic Acid results in decreased expression of E2F1 protein]15222754
D014580Ursodeoxycholic Acid[Ursodeoxycholic Acid co-treated with TGFB1 protein] results in increased localization of NR3C2 protein15222754
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [TGFB1 protein results in decreased expression of NR3C2 mRNA]15222754
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [TGFB1 protein results in decreased expression of NR3C2 protein]15222754
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of NR3C2 mRNA15222754
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased localization of NR3C2 protein15222754
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR3C2 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of NR3C2 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of NR3C2 mRNA24383497|2493525
D014635Valproic AcidValproic Acid results in increased methylation of NR3C2 gene29154799
D014638VanadatesVanadates results in decreased expression of NR3C2 mRNA22714537
D000069470Venlafaxine HydrochlorideVenlafaxine Hydrochloride results in decreased expression of NR3C2 mRNA11406320
C025643vinclozolinvinclozolin binds to and results in decreased activity of NR3C2 protein16750840
D014867WaterNR3C2 protein affects the abundance of Water15802372
D015038ZinebZineb inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]29149346
D015038ZinebZineb inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]29149346

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0003700DNA-binding transcription factor activity-TAS3037703  
GO:0003707steroid hormone receptor activity-TAS9662404  
GO:0005496steroid binding-IEA-  
GO:0005515protein binding-IPI11518808  
GO:0008270zinc ion binding-IEA-  
GO:0043565sequence-specific DNA binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0007165signal transduction-TAS3037703  
GO:0043401steroid hormone mediated signaling pathway-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005789endoplasmic reticulum membrane-IEA-  
GO:0005829cytosol-TAS-  
GO:0043235receptor complex-IDA23382219  
KEGG ID KEGG Term
hsa04960Aldosterone-regulated sodium reabsorption
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2262752Cellular responses to stressTAS
R-HSA-3371497HSP90 chaperone cycle for steroid hormone receptors (SHR)TAS
R-HSA-383280Nuclear Receptor transcription pathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8953897Cellular responses to external stimuliTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26228405Corticosteroid receptor genes and childhood neglect influence susceptibility to crack/cocaine addiction and response to detoxification treatment. (2015 Sep)Rovaris DLJ Psychiatr Res
24845178Stress-related genes and heroin addiction: a role for a functional FKBP5 haplotype. (2014 Jul)Levran OPsychoneuroendocrinology
21036197NTM and NR3C2 polymorphisms influencing intelligence: family-based association studies. (2011 Jan 15)Pan YProg Neuropsychopharmacol Biol Psychiatry
26275702A NR3C2 haplotype increases the risk of alcoholism in schizophrenic patients in Han Chinese population. (2015 Oct 30)Tang LPsychiatry Res
27397864Glucocorticoid receptor gene modulates severity of depression in women with crack cocaine addiction. (2016 Sep)Rovaris DLEur Neuropsychopharmacol
21471972Inefficient arterial hypertension control in patients with metabolic syndrome and its link to renin-angiotensin-aldosterone system polymorphisms. (2011 Jun)Morales-Suarez-Varela MMHypertens Res
24766650Drug addiction and stress-response genetic variability: association study in African Americans. (2014 Jul)Levran OAnn Hum Genet