Gene: MMP1

4312
CLG|CLGN
matrix metallopeptidase 1
protein-coding
11q22.2
Ensembl:ENSG00000196611 MIM:120353 Vega:OTTHUMG00000048192 UniprotKB:P03956
NG_011740.1
PubMed
ND|AD
31   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.880e-1 (AD)  7.590e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PPY0.534
FBN20.436
OR4F170.401
MMP30.37
HSD17B20.367
OR10A60.36
AMTN0.351
INHBA0.35
CCL130.35
PLEKHN10.345

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SYCE1-0.343
DHRS4L2-0.296
COL28A1-0.275
RHOXF1-0.248
TP53TG3D-0.236
RHCG-0.233
PFKFB1-0.23
MYH7B-0.23
IQCA1-0.226
CCDC24-0.223

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00786MarimastatSmall Molecule154039-60-8Approved|InvestigationalTarget
DB07556N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDESmall MoleculeExperimentalTarget
DB07926N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDESmall MoleculeExperimentalTarget
DB08403METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACIDSmall MoleculeExperimentalTarget
DB08482[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTERSmall MoleculeExperimentalTarget
DB08491N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDESmall MoleculeExperimentalTarget
ID Drug Name Action PubMed
C4350441-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]22936809
C5691071-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one results in decreased activity of MMP1 protein"23826121
D0140131,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]"16987005
C5403601-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin"1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin results in decreased expression of MMP1 mRNA"19330880
C5403601-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin"1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin results in decreased expression of MMP1 protein"19330880
C09724015-deoxy-delta(12,14)-prostaglandin J2"[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"Cycloheximide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"Dactinomycin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"HMOX1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein]"19136476
C09724015-deoxy-delta(12,14)-prostaglandin J2"NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]"19136476
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]"21245013
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]"21245013
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cholesterol, LDL metabolite results in increased expression of MMP1 mRNA]"11414687
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [EGF protein results in increased secretion of MMP1 protein]17656145
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]17656145
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased secretion of MMP1 protein]17656145
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]19765281
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [IL24 protein results in increased expression of MMP1 protein]25168428
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]17449795
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]17449795
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of MMP1 mRNA11414687
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [SB 203580 results in increased expression of MMP1 mRNA]11297530
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]11297530
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of MMP1 mRNA11297530
C1202272-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide"2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in decreased expression of MMP1 protein"21742783
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]19561517
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]21245013
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of MMP1 protein19393235|2232678
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of MMP1 mRNA19393235|2232678
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]28655636
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]23625689
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]28655636
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased expression of MMP1 mRNA23625689
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [IL24 protein results in increased expression of MMP1 protein]"25168428
C0005949583,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide"3,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]"26107568
C0005949583,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide"3,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]"26107568
C0144643,4-dichloroaniline"3,4-dichloroaniline results in increased expression of MMP1 mRNA"24172598
C0492463-hydroxypicolinic acid3-hydroxypicolinic acid results in decreased activity of MMP1 protein21189019
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]19765281
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]"22936809
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased activity of MMP1 protein14672615
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of MMP1 mRNA14672615
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]]"20426787
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [IL1B protein results in increased expression of MMP1 mRNA]"20426787
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"[6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased activity of SIRT1 protein] promotes the reaction [IL1B protein results in increased expression of MMP1 protein]"20426787
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"[6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased activity of SIRT1 protein] which results in increased expression of MMP1 mRNA"20426787
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"[6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased activity of SIRT1 protein] which results in increased expression of MMP1 protein"20426787
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased expression of MMP1 mRNA"20426787
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA]"10836612
C0920067-Ala-angiotensin (1-7)7-Ala-angiotensin (1-7) inhibits the reaction [AGT protein modified form results in increased activity of MMP1 protein]20837116
C0920067-Ala-angiotensin (1-7)7-Ala-angiotensin (1-7) results in decreased activity of MMP1 protein20837116
C514876AAL 881AAL 881 inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
C514876AAL 881AAL 881 inhibits the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
D000079AcetaldehydeAcetaldehyde results in decreased expression of MMP1 mRNA7934638
D000082AcetaminophenAcetaminophen results in increased expression of MMP1 mRNA21420995
C006358acetohydroxamic acidacetohydroxamic acid binds to and results in decreased activity of MMP1 protein16522091
C094432acetyl-11-ketoboswellic acid[acetyl-11-ketoboswellic acid co-treated with arsenic trioxide] results in decreased activity of MMP1 protein21078271
C094432acetyl-11-ketoboswellic acid[acetyl-11-ketoboswellic acid co-treated with arsenic trioxide] results in decreased expression of MMP1 mRNA21078271
C094432acetyl-11-ketoboswellic acid[acetyl-11-ketoboswellic acid co-treated with arsenic trioxide] results in decreased secretion of MMP1 protein21078271
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]"19136476
D000111AcetylcysteineAcetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]21635667
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]17449795
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]17449795
D000111AcetylcysteineAcetylcysteine inhibits the reaction [SOD2 protein results in increased expression of MMP1]21749277
D000171AcroleinAcrolein results in increased expression of MMP1 mRNA21742783
D000171AcroleinAcrolein results in increased secretion of MMP1 protein21742783
C482289Ageladine AAgeladine A results in decreased activity of MMP1 protein21413800
D000447AldehydesAldehydes results in increased expression of MMP1 mRNA25014914
D013196DihydrotestosteroneDihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]8798622
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]15075337
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]15075337
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP1 mRNA]19022365
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of MMP1 mRNA21298039
D000537Aluminum OxideAluminum Oxide results in increased expression of MMP1 mRNA16488289
D000622Aminolevulinic AcidAminolevulinic Acid affects the expression of MMP1 mRNA12542540
D000622Aminolevulinic AcidAminolevulinic Acid affects the expression of MMP1 protein12542540
D000622Aminolevulinic AcidSodium Azide inhibits the reaction [Aminolevulinic Acid affects the expression of MMP1 protein]12542540
D006710HomocysteineDizocilpine Maleate inhibits the reaction [Homocysteine analog results in decreased expression of and results in decreased activity of MMP1 protein]20406136
D006710HomocysteineHomocysteine analog results in decreased expression of and results in decreased activity of MMP1 protein20406136
D000640Amitrole[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA10464329
D000640AmitroleDeferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]10464329
C078814anandamideanandamide results in increased expression of MMP1 mRNA16330497
D000728AndrogensAndrogens affects the expression of MMP1 protein17607299
D047310ApigeninApigenin results in decreased expression of MMP1 mRNA21112745
D047310ApigeninApigenin results in decreased expression of MMP1 protein21112745
C047981arginyl-glycyl-aspartic acidarginyl-glycyl-aspartic acid results in increased expression of MMP115547672
D001151ArsenicArsenic results in increased expression of MMP1 mRNA12928151
C006632arsenic trioxide[acetyl-11-ketoboswellic acid co-treated with arsenic trioxide] results in decreased activity of MMP1 protein21078271
C006632arsenic trioxide[acetyl-11-ketoboswellic acid co-treated with arsenic trioxide] results in decreased expression of MMP1 mRNA21078271
C006632arsenic trioxide[acetyl-11-ketoboswellic acid co-treated with arsenic trioxide] results in decreased secretion of MMP1 protein21078271
C006632arsenic trioxidearsenic trioxide inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]23253724
C006632arsenic trioxidearsenic trioxide inhibits the reaction [TNF protein results in increased secretion of and results in increased activity of MMP1 protein]23253724
C006632arsenic trioxidearsenic trioxide results in decreased expression of MMP1 mRNA15761015|2325372
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of MMP1 mRNA"24160326|2535159
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of MMP1 protein"16966607
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of MMP1 protein"16966607
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA]10836612
D001374AzacitidineAzacitidine results in increased expression of MMP1 mRNA20823114
C406592azaspiracidazaspiracid results in increased expression of MMP1 mRNA28939011
C547126AZM551248AZM551248 results in decreased activity of MMP1 protein22323515
C547126AZM551248AZM551248 results in increased expression of MMP1 mRNA22323515
C022921benzo(k)fluorantheneAcetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]21635667
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased expression of MMP1 mRNA21635667
C022921benzo(k)fluorantheneSB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]21635667
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of MMP1 mRNA15808406|1806139
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of MMP1 protein22581694
D001564Benzo(a)pyrenealpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP1 mRNA]19022365
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of MMP1 mRNA19022365
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of MMP1 mRNA"20382639
D004958Estradiolbisphenol A inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]]20600708
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of MMP1 mRNA20660070
D004958EstradiolEstradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]20600708
D004958EstradiolEstradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein modified form]22219637
D004958EstradiolEstradiol promotes the reaction [ESR1 protein binds to MMP1 promoter]17157789
D004958EstradiolEstradiol promotes the reaction [FOS protein binds to MMP1 promoter]17157789
D004958EstradiolEstradiol results in decreased expression of MMP1 mRNA21795739
D004958EstradiolEstradiol results in increased expression of MMP1 mRNA20106945
D004958Estradiolfulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]]20600708
D004958Estradiol[Progesterone co-treated with Estradiol] results in decreased expression of MMP1 mRNA17404688
C095105bexarotenebexarotene results in decreased expression of MMP1 mRNA17178900
C006780bisphenol Abisphenol A inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]]20600708
C006780bisphenol Abisphenol A results in decreased expression of MMP1 mRNA25181051
D001761BleomycinBleomycin results in increased expression of MMP1 mRNA18684396
D001761BleomycinBleomycin results in increased expression of MMP1 protein18684396
C022777bufalinbufalin results in decreased expression of MMP1 protein23949904
D019328Buthionine Sulfoximine[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA10464329
D019328Buthionine SulfoximineDeferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]10464329
C018475butyraldehydebutyraldehyde results in increased expression of MMP1 mRNA26079696
D002104CadmiumCadmium results in increased expression of MMP1 mRNA22562489
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [Oxygen deficiency results in decreased expression of MMP1 mRNA]20193091
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of MMP1 mRNA26472689
D002118CalciumCalcium affects the expression of MMP1 mRNA17508023
D002118CalciumCalcium affects the expression of MMP1 protein17508023
C073718cannabidiol hydroxyquinonecannabidiol hydroxyquinone results in increased expression of MMP1 mRNA16571653
D002211CapsaicinCapsaicin results in increased expression of MMP1 mRNA21310942
D002211CapsaicinCapsaicin results in increased expression of MMP1 protein17508023
D002211Capsaicincapsazepine inhibits the reaction [Capsaicin results in increased expression of MMP1 protein]17508023
C071423capsazepinecapsazepine affects the expression of MMP1 mRNA17508023
C071423capsazepinecapsazepine affects the expression of MMP1 protein17508023
C071423capsazepinecapsazepine inhibits the reaction [Capsaicin results in increased expression of MMP1 protein]17508023
D002220CarbamazepineCarbamazepine affects the expression of MMP1 mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of MMP1 mRNA16508911
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of MMP1 protein16508911
D002251Carbon TetrachloridePOMC protein promotes the reaction [Carbon Tetrachloride results in increased expression of MMP1 protein]16508911
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of MMP1 protein17094476
C097658CGS 27023ACGS 27023A affects the activity of MMP1 protein22017477
C100187chloropicrinchloropicrin results in increased expression of MMP1 mRNA26352163|2847649
D008078Cholesterol, LDL"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cholesterol, LDL metabolite results in increased expression of MMP1 mRNA]"11414687
D008078Cholesterol, LDL"Cholesterol, LDL metabolite results in increased expression of MMP1 mRNA"11414687
D008078Cholesterol, LDL"Cholesterol, LDL metabolite results in increased expression of MMP1 protein"11414687
D008078Cholesterol, LDL"MAPK1 protein promotes the reaction [Cholesterol, LDL metabolite results in increased expression of MMP1 mRNA]"11414687
D008078Cholesterol, LDL"MAPK3 protein promotes the reaction [Cholesterol, LDL metabolite results in increased expression of MMP1 mRNA]"11414687
D008078Cholesterol, LDL"Quercetin inhibits the reaction [Cholesterol, LDL metabolite results in increased expression of MMP1 mRNA]"11414687
D008078Cholesterol, LDL"Quercetin inhibits the reaction [Cholesterol, LDL metabolite results in increased expression of MMP1 protein]"11414687
D002857ChromiumChromium results in increased expression of MMP1 mRNA15878362
D002857ChromiumGenistein inhibits the reaction [Chromium results in increased expression of MMP1 mRNA]15878362
D002857Chromiumherbimycin inhibits the reaction [Chromium results in increased expression of MMP1 mRNA]15878362
D002939CiprofloxacinCiprofloxacin promotes the reaction [IL1B protein results in increased expression of MMP1 mRNA]12428247|1614802
D002939CiprofloxacinCiprofloxacin promotes the reaction [IL1B protein results in increased secretion of MMP1 protein]16148020
D002939CiprofloxacinCiprofloxacin results in increased expression of MMP1 mRNA12428247
D002994ClofibrateClofibrate inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]16572457
D002994Clofibrate[Clofibrate promotes the reaction [IL1B protein results in increased expression of IL1RN mRNA]] which results in increased expression of MMP1 mRNA16572457
D060729Coal AshCoal Ash results in decreased expression of MMP1 mRNA19000753
D060729Coal AshCoal Ash results in increased expression of MMP1 mRNA18684396
D060729Coal AshCoal Ash results in increased expression of MMP1 protein18684396
D003035CobaltCobalt results in increased expression of MMP1 mRNA15878362
D003035CobaltGenistein inhibits the reaction [Cobalt results in increased expression of MMP1 mRNA]15878362
D003035Cobaltherbimycin inhibits the reaction [Cobalt results in increased expression of MMP1 mRNA]15878362
D003035Cobalt[tungsten carbide binds to Cobalt] which results in decreased expression of MMP1 mRNA20105288
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]20110250|2215530
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]20110250
C007095cobaltiprotoporphyrincobaltiprotoporphyrin results in decreased expression of MMP1 mRNA20110250
C007095cobaltiprotoporphyrin[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] which results in decreased expression of MMP1 mRNA18200630
C007095cobaltiprotoporphyrin[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] which results in decreased expression of MMP1 protein18200630
C007095cobaltiprotoporphyrincobaltiprotoporphyrin results in increased expression of MMP1 protein19136476
C007095cobaltiprotoporphyrinHMOX1 protein promotes the reaction [cobaltiprotoporphyrin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]]20110250
C007095cobaltiprotoporphyrinHMOX1 protein promotes the reaction [cobaltiprotoporphyrin inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]]20110250
C018021cobaltous chloridecobaltous chloride results in decreased expression of MMP1 mRNA20105288
D005576ColforsinColforsin results in increased expression of MMP1 mRNA24784705
D005576ColforsinJM 3100 inhibits the reaction [Colforsin results in increased expression of MMP1 mRNA]24784705
D003300Copper[Organoselenium Compounds binds to Copper] which results in increased expression of MMP1 mRNA25167922
D003300CopperCopper results in increased expression of MMP1 mRNA20053132
D003300CopperCopper results in increased expression of MMP1 protein20053132
D019327Copper SulfateCopper Sulfate results in increased expression of MMP1 mRNA19549813
D003471CuprizoneCuprizone results in decreased expression of MMP1 mRNA27523638
D003474CurcuminCurcumin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]16807698
D003513Cycloheximide"Cycloheximide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]"19136476
D003513CycloheximideCycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]15075337
D016572CyclosporineCyclosporine results in decreased expression of MMP1 mRNA22147139
D016572CyclosporineCyclosporine results in increased expression of MMP1 mRNA10914799|2010694
D016572CyclosporineCyclosporine affects the expression of MMP1 protein18166100
D003540CystathionineCystathionine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein]27664576
D003545CysteineCysteine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein]27664576
D003609Dactinomycin"Dactinomycin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]"19136476
D000069439DasatinibDasatinib results in decreased expression of MMP1 mRNA20579391
C014347decitabinedecitabine affects the expression of MMP1 mRNA17145863
D003676Deferoxamine[Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA10464329
D003676Deferoxamine"Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]"19136476
D003676Deferoxamine"Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]"19136476
D003676DeferoxamineDeferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]10464329
D003676DeferoxamineDeferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]10464329
C107676deguelindeguelin results in decreased expression of MMP1 protein25322282
D013759DronabinolDronabinol results in increased expression of MMP1 mRNA16330497
D003907DexamethasoneDexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]20858459
D003907DexamethasoneDexamethasone results in decreased expression of MMP1 mRNA25047013
D003907DexamethasoneDexamethasone results in decreased secretion of MMP1 protein15698539
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone results in decreased secretion of MMP1 protein]15698539
D002945Cisplatin[Cisplatin co-treated with Paclitaxel] results in decreased expression of MMP1 mRNA20705681
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in decreased expression of MMP1 mRNA26924002
D019259LamivudineLamivudine results in increased expression of MMP1 protein15309715
C503840dieckoldieckol results in decreased expression of MMP1 mRNA19330880
C503840dieckoldieckol results in decreased expression of MMP1 protein19330880
D000875AnthralinAnthralin results in decreased activity of MMP1 protein23611293
D002117CalcitriolCalcitriol results in increased expression of MMP1 mRNA12040012|1600243
C472511dimethylarsinous aciddimethylarsinous acid results in increased expression of MMP1 mRNA23876855
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of MMP1 mRNA16270385
D004128Dimethylnitrosamine"Drugs, Chinese Herbal inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]"16270385
D004128DimethylnitrosamineFlavonoids inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]16270385
D004128DimethylnitrosaminePlant Preparations inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]16270385
C024629dimethyl phthalatedimethyl phthalate affects the expression of MMP1 mRNA26924002
D004121Dimethyl SulfoxideDimethyl Sulfoxide results in increased expression of MMP1 mRNA18684396
D004121Dimethyl SulfoxideDimethyl Sulfoxide results in increased expression of MMP1 protein18684396
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of MMP1 mRNA20146380
C051904dinophysistoxin 1dinophysistoxin 1 results in increased expression of MMP1 mRNA28939011
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]17449795
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]17449795
D004237DiuronDiuron metabolite results in increased expression of MMP1 mRNA24172598
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in decreased expression of MMP1 mRNA]20406136
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [Homocysteine analog results in decreased expression of and results in decreased activity of MMP1 protein]20406136
D004317DoxorubicinMMP1 protein affects the susceptibility to Doxorubicin16217747
D004317DoxorubicinMMP1 protein results in decreased susceptibility to Doxorubicin11313874
D004317DoxorubicinDoxorubicin results in increased expression of MMP1 protein17609194
D004317DoxorubicinDoxorubicin results in increased activity of MMP1 protein19782292
D004317DoxorubicinDoxorubicin results in increased expression of MMP1 mRNA19782292
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]"16270385
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]21245013
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
D004610Ellagic AcidEllagic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1]22739086
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]16206353
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of MMP1 mRNA22079256
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of MMP1 mRNA23550701
D005047EtoposideEtoposide results in decreased expression of MMP1 protein18557930
D005047Etoposidepifithrin inhibits the reaction [Etoposide results in decreased expression of MMP1 protein]18557930
D015738FamotidineFamotidine inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]17656145
D015738FamotidineFamotidine inhibits the reaction [Histamine results in increased secretion of MMP1 protein]17656145
C093323farnesylthiosalicylic acidfarnesylthiosalicylic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
D011345FenofibrateFenofibrate results in decreased expression of MMP1 protein25545733
D005419FlavonoidsFlavonoids inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]16270385
D005472FluorouracilFluorouracil results in increased expression of MMP1 mRNA19528421
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MMP1 mRNA]15016801
D005492Folic AcidDizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in decreased expression of MMP1 mRNA]20406136
D005492Folic AcidFolic Acid deficiency results in decreased activity of MMP1 protein20406136
D005492Folic AcidFolic Acid deficiency results in decreased expression of MMP1 mRNA20406136
D005557FormaldehydeCystathionine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein]27664576
D005557FormaldehydeCysteine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein]27664576
D005557FormaldehydeFormaldehyde results in decreased expression of MMP1 mRNA28937961
D005557FormaldehydeFormaldehyde results in increased expression of MMP1 mRNA27664576
D005557FormaldehydeFormaldehyde results in increased expression of MMP1 protein27664576
C067584formosanin Cformosanin C results in decreased expression of MMP1 protein21304274
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]]20600708
C064925gadodiamide2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]19561517
C064925gadodiamidegadodiamide results in increased expression of MMP1 mRNA19561517
C064925gadodiamidegadodiamide results in increased expression of MMP1 protein19561517
C064925gadodiamideU 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]19561517
C001277geldanamycin[geldanamycin co-treated with PTHLH protein modified form] results in increased expression of MMP1 mRNA12724357
C001277geldanamycingeldanamycin results in decreased expression of MMP1 mRNA26705709
D019833GenisteinGenistein inhibits the reaction [Chromium results in increased expression of MMP1 mRNA]15878362
D019833GenisteinGenistein inhibits the reaction [Cobalt results in increased expression of MMP1 mRNA]15878362
D019833GenisteinGenistein inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA]15878362
D019833GenisteinGenistein results in decreased expression of MMP1 mRNA22228119
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1]]18625914
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]18625914
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 mRNA]17303772
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 protein]17303772
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased secretion of MMP1 protein]17303772
D005944GlucosamineGlucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]15144122
D005944GlucosamineGlucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]18080321
D005944GlucosamineGlucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]18080321
D005944GlucosamineGlucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]17925024
D005944GlucosamineGlucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]17925024
D005947GlucoseCD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]18180316
C010178heliotrineheliotrine results in increased expression of MMP1 mRNA26100227
D006427HeminHemin results in increased expression of MMP1 protein19136476
D006493HeparinHeparin results in decreased activity of MMP1 protein10958381
C020754herbimycinherbimycin inhibits the reaction [Chromium results in increased expression of MMP1 mRNA]15878362
C020754herbimycinherbimycin inhibits the reaction [Cobalt results in increased expression of MMP1 mRNA]15878362
C020754herbimycinherbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA]15878362
D006632Histamine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]17656145
D006632Histamine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased secretion of MMP1 protein]17656145
D006632HistamineEGFR protein affects the reaction [Histamine results in increased secretion of MMP1 protein]17656145
D006632HistamineFamotidine inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]17656145
D006632HistamineFamotidine inhibits the reaction [Histamine results in increased secretion of MMP1 protein]17656145
D006632HistamineHistamine results in increased expression of MMP1 mRNA17656145|9856766
D006632HistamineHistamine results in increased secretion of MMP1 protein17656145
D006632Histaminetyrphostin AG 1478 inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]17656145
D006632Histaminetyrphostin AG 1478 inhibits the reaction [Histamine results in increased secretion of MMP1 protein]17656145
D006820Hyaluronic Acid[Hyaluronic Acid co-treated with resveratrol] results in decreased expression of MMP1 mRNA23595953
D006851Hydrochloric AcidHydrochloric Acid results in increased expression of MMP1 protein11850527
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of MMP1 mRNA20044591
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of MMP1 protein22580338
D006861Hydrogen PeroxideCAT protein inhibits the reaction [[[SOD2 protein results in increased abundance of Hydrogen Peroxide] results in increased phosphorylation of and results in increased activity of [MAPK3 protein co-treated with MAPK1 protein]] which affects the expression of MMP1]11297530
D006861Hydrogen PeroxideCAT protein inhibits the reaction [[SOD2 protein results in increased chemical synthesis of Hydrogen Peroxide] which results in increased expression of MMP1 mRNA]12538496
D006861Hydrogen Peroxide[[SOD2 protein results in increased abundance of Hydrogen Peroxide] results in increased phosphorylation of and results in increased activity of [MAPK3 protein co-treated with MAPK1 protein]] which affects the expression of MMP111297530
D006861Hydrogen Peroxide[SOD2 protein results in increased chemical synthesis of Hydrogen Peroxide] which results in increased expression of MMP1 mRNA12538496
D007052IbuprofenIbuprofen results in increased expression of MMP1 mRNA16580899
C119203ilomastatilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]18837084
C119203ilomastatilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA]18837084
C075954indolo(3,2-b)carbazole"indolo(3,2-b)carbazole results in increased expression of MMP1 mRNA"18061397
D007213IndomethacinIndomethacin results in increased activity of MMP1 protein17000239
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MMP1 mRNA25613284
D007501Iron"[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein"19136476
D007501Iron"[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA"19136476
D007501Iron"Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]"19136476
D007545IsoproterenolIsoproterenol results in increased expression of MMP112883319
D007545IsoproterenolSI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP1]12883319
C088327JM 3100JM 3100 inhibits the reaction [Colforsin results in increased expression of MMP1 mRNA]24784705
C561695(+)-JQ1 compound[(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of MMP1 mRNA27169980
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of MMP1 mRNA24796395|2596192
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of MMP1 protein26324948
C561695(+)-JQ1 compound[PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of MMP1 mRNA25119042
C514877LBT 613LBT 613 inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
C514877LBT 613LBT 613 inhibits the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 mRNA]"18986645
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]"18986645
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 mRNA"18986645
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein"18986645
C433788lipopolysaccharide, E. coli O26-B6"Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 mRNA]"18986645
C433788lipopolysaccharide, E. coli O26-B6"Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]"18986645
C433788lipopolysaccharide, E. coli O26-B6"Polymyxin B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]]"18986645
C433788lipopolysaccharide, E. coli O26-B6"Polymyxin B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]"18986645
C433788lipopolysaccharide, E. coli O26-B6"Polymyxin B inhibits the reaction [Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]]"18986645
C433788lipopolysaccharide, E. coli O26-B6"Tubocurarine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]]"18986645
C433788lipopolysaccharide, E. coli O26-B6"Tubocurarine inhibits the reaction [Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]]"18986645
D008070Lipopolysaccharides2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
D008070LipopolysaccharidesCD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]18180316
D008070Lipopolysaccharidesfarnesylthiosalicylic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
D008070Lipopolysaccharidesgeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1]]18625914
D008070Lipopolysaccharidesgeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]18625914
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of MMP1 mRNA18625914|1868439
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of MMP1 protein17303203|1868439
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of MMP1 protein18625914
D008070LipopolysaccharidesMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]18625914
D008070LipopolysaccharidesNSC 23766 inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
D008070LipopolysaccharidesPGGT1B inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
D008070LipopolysaccharidesSimvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1 mRNA]18625914
D008070LipopolysaccharidesSimvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Zymosan] results in decreased activity of MMP1 protein15259001
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Zymosan] results in increased activity of MMP1 protein15259001
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of MMP1 protein11850527
D018021Lithium ChlorideLithium Chloride results in increased expression of MMP1 mRNA19407340
D018021Lithium ChlorideLithium Chloride results in increased expression of MMP1 protein19407340
D018021Lithium ChlorideTP53 protein promotes the reaction [Lithium Chloride results in increased expression of MMP1 mRNA]19407340
D008154LucanthoneLucanthone results in increased expression of MMP1 mRNA21148553
D047311LuteolinLuteolin results in decreased expression of MMP1 mRNA21112745
D047311LuteolinLuteolin results in decreased expression of MMP1 protein21112745
C008316maltolmaltol binds to and results in decreased activity of MMP1 protein16522091
C551151manganese ferritemanganese ferrite results in increased secretion of MMP1 protein24885771
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP1 protein]17395008
D061965Matrix Metalloproteinase InhibitorsMatrix Metalloproteinase Inhibitors inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]19765281
D061965Matrix Metalloproteinase InhibitorsMatrix Metalloproteinase Inhibitors inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]19765281
D017258Medroxyprogesterone AcetateMedroxyprogesterone Acetate results in decreased expression of MMP1 mRNA20843944
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of MMP1 mRNA11817102
C088155methanandamidemethanandamide results in increased expression of MMP1 mRNA16330497
C088155methanandamidemethanandamide results in increased expression of MMP1 protein16330497
D008727MethotrexateMethotrexate results in increased expression of MMP1 mRNA21678067
C000873methylprednisolone acetatemethylprednisolone acetate results in decreased expression of MMP1 mRNA15693093
D015741MetriboloneMetribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]8798622
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]18625914
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of MMP1 mRNA]17303772
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of MMP1 protein]17303772
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in decreased secretion of MMP1 protein]17303772
C100075mibolerone[mibolerone binds to and results in increased activity of AR protein] inhibits the reaction [ETS1 protein results in increased expression of MMP1 mRNA]8798622
C100075mibolerone[mibolerone binds to and results in increased activity of AR protein] inhibits the reaction [ETV4 protein results in increased expression of MMP1 mRNA]8798622
C100075mibolerone[mibolerone binds to and results in increased activity of AR protein] inhibits the reaction [ETV5 protein results in increased expression of MMP1 mRNA]8798622
C100075miboleronemibolerone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]8798622
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone results in decreased secretion of MMP1 protein]15698539
C517284monomethyl phthalatemonomethyl phthalate results in decreased expression of MMP1 mRNA26924002
D019810Sodium AzideSodium Azide inhibits the reaction [Aminolevulinic Acid affects the expression of MMP1 protein]12542540
D019810Sodium AzideSodium Azide inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA]10836612
D009532NickelNickel results in increased expression of MMP1 mRNA25583101
C029938nickel sulfatenickel sulfate results in increased expression of MMP1 mRNA16780908
D009538Nicotine"lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 mRNA]"18986645
D009538Nicotine"lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]"18986645
D009538Nicotine"Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 mRNA]"18986645
D009538Nicotine"Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]"18986645
D009538NicotineNicotine results in increased expression of MMP1 mRNA17151781|1898664
D009538NicotineNicotine results in increased expression of MMP1 protein17151781|1898664
D009538Nicotine"Polymyxin B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]]"18986645
D009538Nicotine"Polymyxin B inhibits the reaction [Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]]"18986645
D009538Nicotine"Tubocurarine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]]"18986645
D009538Nicotine"Tubocurarine inhibits the reaction [Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]]"18986645
D009538NicotineTubocurarine inhibits the reaction [Nicotine results in increased expression of MMP1 mRNA]17151781
D009538NicotineTubocurarine inhibits the reaction [Nicotine results in increased expression of MMP1 protein]18986645
D009543NifedipineNifedipine affects the expression of MMP1 protein18166100
D017672Nitrogen CompoundsNitrogen Compounds analog binds to and results in decreased activity of MMP1 protein16522091
D009643NorfloxacinNorfloxacin promotes the reaction [IL1B protein results in increased expression of MMP1 mRNA]16148020
D009643NorfloxacinNorfloxacin promotes the reaction [IL1B protein results in increased secretion of MMP1 protein]16148020
C487513NSC 23766NSC 23766 inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
D019319Okadaic AcidOkadaic Acid results in increased expression of MMP1 mRNA28939011
D009840OligomycinsOligomycins results in increased secretion of MMP1 protein21742783
D016566Organoselenium Compounds[Organoselenium Compounds binds to Copper] which results in increased expression of MMP1 mRNA25167922
C510784ormosil[ormosil binds to Polyethylene Glycols] which results in increased expression of MMP1 mRNA24888373
D010100OxygenCadmium Chloride inhibits the reaction [Oxygen deficiency results in decreased expression of MMP1 mRNA]20193091
D010100OxygenOxygen deficiency results in decreased expression of MMP1 mRNA20193091
D010100OxygenOxygen deficiency results in decreased expression of MMP1 protein20193091
D010118OxytetracyclineOxytetracycline results in decreased expression of MMP1 mRNA15077693
D017239Paclitaxel[Cisplatin co-treated with Paclitaxel] results in decreased expression of MMP1 mRNA20705681
D017239PaclitaxelMMP1 protein affects the susceptibility to Paclitaxel16217747
D010269Paraquat[Paraquat co-treated with SOD2 protein] results in increased expression of MMP1 mRNA10464329
D052638Particulate Matter2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]17449795
D052638Particulate Matter2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
D052638Particulate Matter2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
D052638Particulate Matter2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]28655636
D052638Particulate MatterAAL 881 inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
D052638Particulate MatterAAL 881 inhibits the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
D052638Particulate MatterAcetylcysteine inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]17449795
D052638Particulate MatterARRB1 protein promotes the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
D052638Particulate MatterARRB1 protein promotes the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
D052638Particulate MatterARRB2 protein promotes the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
D052638Particulate MatterARRB2 protein promotes the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
D052638Particulate Matterdiphenyleneiodonium inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]17449795
D052638Particulate MatterLBT 613 inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
D052638Particulate MatterLBT 613 inhibits the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
D052638Particulate MatterMMP1 gene polymorphism affects the reaction [Particulate Matter results in increased expression of MMP1 mRNA]19337515|1933751
D052638Particulate MatterMMP1 gene SNP affects the susceptibility to Particulate Matter19590686
D052638Particulate MatterNOX4 mutant form inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]17449795
D052638Particulate MatterParticulate Matter results in increased expression of and results in increased activity of MMP1 protein17449795
D052638Particulate MatterParticulate Matter results in increased expression of MMP1 mRNA17449795|1933751
D052638Particulate MatterParticulate Matter results in increased expression of MMP1 protein28341207
D052638Particulate MatterParticulate Matter results in increased secretion of MMP1 protein19337515
D052638Particulate MatterU 0126 inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
D052638Particulate MatterU 0126 inhibits the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
C497431PD-0200347PD-0200347 results in decreased expression of MMP1 protein15693013
C506614PD 0325901[PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of MMP1 mRNA25119042
C506614PD 0325901PD 0325901 results in decreased expression of MMP1 mRNA25119042
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of MMP1 mRNA26705709
C046012pentanalpentanal results in increased expression of MMP1 mRNA26079696
D010455PeptidesPeptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]20004183
D010455PeptidesPeptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]20004183
D010457PeptidoglycanPeptidoglycan results in increased expression of MMP1 mRNA15860229
D010634PhenobarbitalPhenobarbital affects the expression of MMP1 mRNA19159669
D010672PhenytoinPhenytoin results in decreased expression of MMP1 mRNA15948689
D010672PhenytoinPhenytoin results in increased expression of MMP1 mRNA10914799|1474168
D010672PhenytoinPhenytoin affects the expression of MMP1 protein18166100
C008876phorbol-12,13-didecanoate"phorbol-12,13-didecanoate results in increased secretion of MMP1 protein"21245013
D064801Phospholipase A2 InhibitorsPhospholipase A2 Inhibitors inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]19765281
D064801Phospholipase A2 InhibitorsPhospholipase A2 Inhibitors inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]19765281
D064801Phospholipase A2 InhibitorsPhospholipase A2 Inhibitors results in decreased expression of MMP1 mRNA19765281
D010767PhosphorylcholineGenistein inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA]15878362
D010767Phosphorylcholineherbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA]15878362
D010767PhosphorylcholinePhosphorylcholine analog results in increased expression of MMP1 mRNA15878362
C030614picolinic acidpicolinic acid binds to and results in decreased activity of MMP1 protein16522091
C121565pifithrinpifithrin inhibits the reaction [Etoposide results in decreased expression of MMP1 protein]18557930
D010936Plant ExtractsPlant Extracts results in increased expression of MMP1 mRNA18061397
D010938Plant OilsPlant Oils results in increased expression of MMP1 mRNA23370395
D028321Plant PreparationsPlant Preparations inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]16270385
D011092Polyethylene Glycols[ormosil binds to Polyethylene Glycols] which results in increased expression of MMP1 mRNA24888373
D011112Polymyxin B"Polymyxin B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]]"18986645
D011112Polymyxin B"Polymyxin B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]"18986645
D011112Polymyxin B"Polymyxin B inhibits the reaction [Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]]"18986645
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of MMP1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of MMP1 mRNA22079256
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of MMP1 mRNA20660070
D011374Progesterone[Progesterone co-treated with Estradiol] results in decreased expression of MMP1 mRNA17404688
D011374ProgesteroneProgesterone inhibits the reaction [IL1B protein results in increased expression of MMP1 protein modified form]22219637
D011374ProgesteroneProgesterone affects the expression of MMP1 protein17118170
C005556propionaldehydepropionaldehyde results in increased expression of MMP1 mRNA26079696
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of MMP1 mRNA]12832416
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]20004183
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of MMP1 mRNA"21152443
D011763Pyrrolizidine AlkaloidsPyrrolizidine Alkaloids results in increased expression of MMP1 mRNA26100227
D011791QuartzQuartz results in increased expression of MMP1 mRNA27381660
D011794Quercetin"Quercetin inhibits the reaction [Cholesterol, LDL metabolite results in increased expression of MMP1 mRNA]"11414687
D011794Quercetin"Quercetin inhibits the reaction [Cholesterol, LDL metabolite results in increased expression of MMP1 protein]"11414687
D011794QuercetinQuercetin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]22592909
D011794QuercetinQuercetin inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]22592909
D011794QuercetinQuercetin inhibits the reaction [MAPK1 protein results in increased expression of MMP1 mRNA]11414687
D011794QuercetinQuercetin inhibits the reaction [MAPK3 protein results in increased expression of MMP1 mRNA]11414687
D011794QuercetinQuercetin results in decreased expression of MMP1 mRNA11414687|1272435
D011794QuercetinQuercetin results in decreased expression of MMP1 protein11414687|2259290
D011794QuercetinQuercetin results in increased expression of MMP1 mRNA21632981
D017382Reactive Oxygen Species"[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein"19136476
D017382Reactive Oxygen Species"Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]"19136476
C059514resveratrol"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]]"20426787
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]18759268
C059514resveratrolresveratrol inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]23257246
C059514resveratrol[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]20426787
C059514resveratrolSIRT1 mutant form inhibits the reaction [resveratrol inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]]23257246
C059514resveratrol[Hyaluronic Acid co-treated with resveratrol] results in decreased expression of MMP1 mRNA23595953
C059514resveratrolresveratrol affects the expression of MMP124066520
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]22936809
D012176RetinoidsRetinoids analog results in decreased expression of MMP1 protein16055107
C116926rofecoxibrofecoxib results in increased expression of MMP1 mRNA16580899
D012430Ruthenium RedRuthenium Red affects the expression of MMP1 mRNA17508023
D012430Ruthenium RedRuthenium Red affects the expression of MMP1 protein17508023
D012430Ruthenium RedRuthenium Red inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
C093642SB 203580SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]21635667
C093642SB 203580SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]20004183
C093642SB 2035802-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [SB 203580 results in increased expression of MMP1 mRNA]11297530
C093642SB 203580SB 203580 results in increased expression of MMP1 mRNA11297530
D012645SelenomethionineSelenomethionine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]16206353
C507164seletinoid Gseletinoid G results in decreased expression of MMP1 protein16055107
C009237senecioninesenecionine results in increased expression of MMP1 mRNA26100227
C009238senkirkinesenkirkine results in increased expression of MMP1 mRNA26100227
C078903seocalcitolseocalcitol results in increased expression of MMP1 mRNA12040012
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of MMP1 mRNA"24160326
C421267SI 27SI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP1]12883319
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of MMP1 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in increased expression of MMP1 mRNA22300531|2535159
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1]]18625914
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]18625914
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 mRNA]17303772
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 protein]17303772
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased secretion of MMP1 protein]17303772
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]18625914
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of MMP1 mRNA]17303772
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of MMP1 protein]17303772
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in decreased secretion of MMP1 protein]17303772
D019821SimvastatinSimvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1 mRNA]18625914
D019821SimvastatinSimvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]18625914
D019821SimvastatinSimvastatin results in decreased expression of MMP1 protein17303772
D019821SimvastatinSimvastatin results in decreased secretion of MMP1 mRNA17303772
D019821SimvastatinSimvastatin results in decreased secretion of MMP1 protein17303772
D019821SimvastatinSimvastatin results in increased expression of MMP1 mRNA17428261
D019821SimvastatinSimvastatin results in decreased expression of MMP119801495
D019821SimvastatinSimvastatin results in decreased expression of MMP1 protein17313769
D020123SirolimusSirolimus results in increased expression of MMP1 mRNA21742783
D020123SirolimusSirolimus results in increased secretion of MMP1 protein21742783
D012906SmokeSmoke results in decreased nitrosation of MMP1 protein21652289
D012906SmokeSmoke results in increased expression of MMP1 mRNA20015843|2109522
D012906SmokeSmoke results in increased secretion of MMP1 protein21742783
D012906SmokeSmoke results in increased expression of MMP1 protein21742783
D012906Smoke[Smoke results in decreased expression of MTOR] which affects the expression of MMP121742783
C017947sodium arsenitesodium arsenite results in decreased expression of MMP1 mRNA12377979
C017947sodium arsenitesodium arsenite results in increased expression of MMP1 mRNA22714537|2387685
D053260SootSoot results in increased expression of MMP1 mRNA18684396
D053260SootSoot results in increased expression of MMP1 protein18684396
D012460SulfasalazineSulfasalazine inhibits the reaction [[IL1A protein co-treated with OSM protein] results in increased expression of MMP1 mRNA]19690126
D012460SulfasalazineSulfasalazine inhibits the reaction [[IL1A protein co-treated with OSM protein] results in increased expression of MMP1 protein]19690126
D012460SulfasalazineSulfasalazine inhibits the reaction [IL1B protein results in increased expression of and results in increased activity of MMP1 protein]16684522
D012460SulfasalazineSulfasalazine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]16684522
D012460SulfasalazineSulfasalazine results in decreased expression of and results in decreased activity of MMP1 protein16684522
C025462sulindac sulfidesulindac sulfide results in decreased expression of MMP1 mRNA15767558
C025462sulindac sulfidesulindac sulfide results in increased expression of MMP1 mRNA16184548
D014284TriiodothyronineTriiodothyronine results in increased expression of MMP1 mRNA21523860
D013605T-2 ToxinT-2 Toxin results in increased expression of MMP1 protein21144892
D013629TamoxifenTamoxifen promotes the reaction [ESR1 protein binds to MMP1 promoter]17157789
D013629TamoxifenTamoxifen promotes the reaction [FOS protein binds to MMP1 promoter]17157789
D013629TamoxifenTamoxifen results in decreased activity of MMP1 protein19393235
D013629TamoxifenTamoxifen results in decreased expression of MMP1 mRNA19393235
D013749Tetrachlorodibenzodioxin2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]23625689
D013749TetrachlorodibenzodioxinAHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]15075337
D013749TetrachlorodibenzodioxinAHR protein promotes the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]15075337
D013749Tetrachlorodibenzodioxinalpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]15075337
D013749Tetrachlorodibenzodioxinalpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]15075337
D013749TetrachlorodibenzodioxinCycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]15075337
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of and results in increased activity of MMP1 protein15982688
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of MMP117003102
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of MMP1 mRNA12377990|1507533
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of MMP1 protein15531779
D013749TetrachlorodibenzodioxinTretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]15075337
D013755Tetradecanoylphorbol AcetateBAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]20858459
D013755Tetradecanoylphorbol AcetateDexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]20858459
D013755Tetradecanoylphorbol AcetateDihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]8798622
D013755Tetradecanoylphorbol AcetateMetribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]8798622
D013755Tetradecanoylphorbol Acetatemibolerone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]8798622
D013755Tetradecanoylphorbol AcetatePeptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]20004183
D013755Tetradecanoylphorbol AcetatePeptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]20004183
D013755Tetradecanoylphorbol Acetatepyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]20004183
D013755Tetradecanoylphorbol AcetateSB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]20004183
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA16176868|2000418
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of MMP1 protein20004183
D013755Tetradecanoylphorbol AcetateTretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]16176868
D013755Tetradecanoylphorbol AcetateU 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]20004183
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MMP1 mRNA25613284
D013853ThioacetamidePOMC protein alternative form promotes the reaction [Thioacetamide results in increased expression of MMP1 mRNA]16511523
D013853ThioacetamideThioacetamide results in increased expression of MMP1 mRNA16511523
D013936Thymidine[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein11103787
D013936ThymidineThymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein]11103787
D013941ThymineThymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein]11103787
C009495titanium dioxide[Vitallium analog binds to titanium dioxide] which results in increased expression of MMP1 mRNA23825117
D014028Tobacco Smoke Pollution"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA]"10836612
D014028Tobacco Smoke PollutionAscorbic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA]10836612
D014028Tobacco Smoke PollutionPPP2R1A protein affects the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA]22223484
D014028Tobacco Smoke PollutionPPP2R1A protein affects the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 protein]22223484
D014028Tobacco Smoke PollutionSodium Azide inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA]10836612
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of MMP1 mRNA10836612|1868439
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of MMP1 protein18684396|2748027
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased secretion of MMP1 protein27404394
D014028Tobacco Smoke PollutionEllagic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1]22739086
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of MMP122739086
C479163tofacitinibtofacitinib results in decreased expression of MMP1 mRNA25398374
C513941tongxinluotongxinluo results in decreased expression of MMP119801495
C513941tongxinluotongxinluo results in decreased expression of MMP1 protein17313769
D019772TopotecanMMP1 protein affects the susceptibility to Topotecan16217747
D014212TretinoinAHR protein promotes the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]15075337
D014212Tretinoinalpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]15075337
D014212TretinoinTretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]16176868
D014212TretinoinTretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]15075337
D014212TretinoinTretinoin results in decreased degradation of MMP1 mRNA15075337
D014212TretinoinTretinoin results in decreased expression of MMP1 mRNA16467367
C012589trichostatin ACAT protein affects the reaction [trichostatin A promotes the reaction [SOD2 protein results in increased expression of MMP1 mRNA]]24973648
C012589trichostatin Atrichostatin A promotes the reaction [SOD2 protein results in increased expression of MMP1 mRNA]24973648
D014302Trinitrobenzenesulfonic Acidilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]18837084
D014302Trinitrobenzenesulfonic Acidilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA]18837084
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA18837084
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of MMP1 protein18837084
D014403Tubocurarine"Tubocurarine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]]"18986645
D014403Tubocurarine"Tubocurarine inhibits the reaction [Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]]"18986645
D014403TubocurarineTubocurarine inhibits the reaction [Nicotine results in increased expression of MMP1 mRNA]17151781
D014403TubocurarineTubocurarine inhibits the reaction [Nicotine results in increased expression of MMP1 protein]18986645
C002802tungsten carbide[tungsten carbide binds to Cobalt] which results in decreased expression of MMP1 mRNA20105288
C002802tungsten carbidetungsten carbide results in decreased expression of MMP1 mRNA20105288
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [EGF protein results in increased secretion of MMP1 protein]17656145
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]17656145
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [Histamine results in increased secretion of MMP1 protein]17656145
C113580U 0126U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]19561517
C113580U 0126U 0126 inhibits the reaction [IL24 protein results in increased expression of MMP1 protein]25168428
C113580U 0126U 0126 inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA polymorphism]19337515
C113580U 0126U 0126 inhibits the reaction [Particulate Matter results in increased secretion of MMP1 protein]19337515
C113580U 0126U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]20004183
C113580U 0126U 0126 results in decreased activity of MMP1 protein19393235|2232678
C113580U 0126U 0126 results in decreased expression of MMP1 mRNA19393235|2232678
C113580U 0126U 0126 inhibits the reaction [SOD2 protein results in increased expression of MMP1 mRNA]11297530
D014638VanadatesVanadates results in increased expression of MMP1 mRNA22714537
D014639VanadiumVanadium results in decreased expression of MMP1 mRNA19000753
C034028vanadyl sulfatevanadyl sulfate results in increased expression of MMP1 mRNA18684396
C034028vanadyl sulfatevanadyl sulfate results in increased expression of MMP1 protein18684396
C545088varespladib methylvarespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]19765281
C545088varespladib methylvarespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]19765281
D001335Vehicle Emissions"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]"21245013
D001335Vehicle Emissions"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]"21245013
D001335Vehicle Emissions2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]17449795
D001335Vehicle Emissions2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]21245013
D001335Vehicle Emissions2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
D001335Vehicle Emissions2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]28655636
D001335Vehicle EmissionsAcetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]17449795
D001335Vehicle Emissionsdiphenyleneiodonium inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]17449795
D001335Vehicle EmissionsEgtazic Acid inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]21245013
D001335Vehicle EmissionsEgtazic Acid inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
D001335Vehicle EmissionsF2RL1 mutant form inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]21245013
D001335Vehicle EmissionsF2RL1 mutant form inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
D001335Vehicle EmissionsF2RL1 protein modified form promotes the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]21245013
D001335Vehicle EmissionsF2RL1 protein modified form promotes the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
D001335Vehicle EmissionsNOX4 mutant form inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]17449795
D001335Vehicle EmissionsRuthenium Red inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
D001335Vehicle EmissionsTRPV4 mutant form inhibits the reaction [F2RL1 protein modified form promotes the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]]21245013
D001335Vehicle EmissionsTRPV4 mutant form inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]21245013
D001335Vehicle EmissionsTRPV4 mutant form inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein]21245013
D001335Vehicle EmissionsVehicle Emissions results in increased expression of and results in increased activity of MMP1 protein17449795
D001335Vehicle EmissionsVehicle Emissions results in increased expression of MMP1 mRNA17449795|2124501
D001335Vehicle EmissionsVehicle Emissions results in increased expression of MMP1 protein18684396
D001335Vehicle EmissionsVehicle Emissions results in increased secretion of MMP1 protein21245013
D001335Vehicle EmissionsVehicle Emissions results in increased expression of MMP1 protein17449795
C551177vemurafenib[(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of MMP1 mRNA27169980
D014747VinblastineMMP1 protein affects the susceptibility to Vinblastine16217747
D014800Vitallium[Vitallium analog binds to titanium dioxide] which results in increased expression of MMP1 mRNA23825117
D024483Vitamin K 3MMP1 affects the susceptibility to Vitamin K 322715409
C009687wortmanninwortmannin inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]22936809
C087958YM 529YM 529 results in decreased expression of and results in decreased activity of MMP1 protein22326785
C087958YM 529YM 529 results in decreased expression of MMP1 mRNA22326785
D015054Zymosan[Lipopolysaccharides co-treated with Zymosan] results in decreased activity of MMP1 protein15259001
D015054Zymosan[Lipopolysaccharides co-treated with Zymosan] results in increased activity of MMP1 protein15259001

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004175endopeptidase activity-IDA19022250  
GO:0004222metalloendopeptidase activity-IDA9920899  
GO:0004222metalloendopeptidase activity-TAS-  
GO:0004252serine-type endopeptidase activity-TAS-  
GO:0008270zinc ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006508proteolysis-IDA15863497  19022250  
GO:0016032viral process-IEA-  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0022617extracellular matrix disassembly-TAS-  
GO:0030574collagen catabolic process-TAS-  
GO:0032461positive regulation of protein oligomerization-IDA19022250  
GO:0044267cellular protein metabolic process-TAS-  
GO:0050900leukocyte migration-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0031012extracellular matrix-IEA-  
KEGG ID KEGG Term
hsa03320PPAR signaling pathway
hsa05200Pathways in cancer
hsa05219Bladder cancer
hsa05323Rheumatoid arthritis
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-1442490Collagen degradationTAS
R-HSA-1442490Collagen degradationIEA
R-HSA-1474228Degradation of the extracellular matrixTAS
R-HSA-1474228Degradation of the extracellular matrixIEA
R-HSA-1474244Extracellular matrix organizationTAS
R-HSA-1474244Extracellular matrix organizationIEA
R-HSA-1592389Activation of Matrix MetalloproteinasesTAS
R-HSA-168256Immune SystemTAS
R-HSA-202733Cell surface interactions at the vascular wallTAS
R-HSA-210991Basigin interactionsTAS
R-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)TAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25503184Analysis of preoperative serum levels of MMP1, -2, and -9 in patients with site-specific head and neck squamous cell cancer. (2014 Dec)Kalfert DAnticancer Res
28956832Multiple Gene-Environment Interactions on the Angiogenesis Gene-Pathway Impact Rectal Cancer Risk and Survival. (2017 Sep 28)Sharafeldin NInt J Environ Res Public Health
19221176Matrix metalloproteinase-1 and matrix metalloproteinase-3 gene promoter polymorphisms are associated with mortality in haemodialysis patients. (2009 Jul)Cozzolino MNephrol Dial Transplant
22371740Genetic variability and the risk of myocardial infarction in Poles under 45 years of age. (2010 Apr 30)Sakowicz AArch Med Sci
22209925Metalloproteases/anti-metalloproteases imbalance in chronic obstructive pulmonary disease: genetic factors and treatment implications. (2011 Dec)Mocchegiani ECurr Opin Pulm Med
28612708Contribution of matrix metalloproteinases-1 genotypes to gastric cancer susceptibility in Taiwan. (2017 Jun)Yang MDBiomedicine (Taipei)
11875051The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. (2002 Mar 1)Joos LHum Mol Genet
15832405No association of the matrix metalloproteinase 1 promoter polymorphism with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in northern China. (2005 Apr 28)Jin XWorld J Gastroenterol
22122519Cigarette smoke extract induces select matrix metalloproteinases and integrin expression in periodontal ligament fibroblasts. (2012 Jun)Bulmanski ZJ Periodontol
20970515Similar gene expression profiles in smokers and patients with moderate COPD. (2011 Feb)Llinas LPulm Pharmacol Ther
28471875Genetic predictors of recovery in low back and lumbar radicular pain. (2017 Aug)Bjorland SPain
19321798Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis. (2009 May)Bradbury PACarcinogenesis
12383023Genetic polymorphisms of matrix metalloproteinases: functional importance in the development of chronic obstructive pulmonary disease? (2002)Wallace AMAm J Pharmacogenomics
22024213A novel gene-environment interaction involved in endometriosis. (2012 Jan)McCarty CAInt J Gynaecol Obstet
18483334Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer. (2008 May)Sauter WCancer Epidemiol Biomarkers Prev
29695550The Association of Matrix Metalloproteinase-1 Promoter Polymorphisms with Breast Cancer. (2018 May-Jun)Hsiao CLIn Vivo
29464021Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction. (2018 Jan 19)Wang HOncotarget
26484568Changes in the expression and protein level of matrix metalloproteinases after exposure to waterpipe tobacco smoke. (2015)Khabour OFInhal Toxicol
15528217Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China. (2005 Feb)Fang SCarcinogenesis
22888638[Association of the MMP3, MMP9, ADAM33 and TIMP3 genes polymorphic markers with development and progression of chronic obstructive pulmonary disease]. (2012 May-Jun)Korytina GFMol Biol (Mosk)
19963114Effect of combined genetic polymorphisms on lung cancer risk in northern Thai women. (2009 Dec)Klinchid JCancer Genet Cytogenet
24638860SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts. (2014 Jul)Engler AJ Mol Med (Berl)
22776467Age at onset of rheumatoid arthritis: association with polymorphisms in the vascular endothelial growth factor A(VEGFA) gene and an intergenic locus between matrix metalloproteinase (MMP) 1 and 3 genes. (2012 Nov-Dec)Chen YClin Exp Rheumatol
24973403CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke. (2014 Aug 15)Moon HGAm J Physiol Lung Cell Mol Physiol
27354592Matrix Metalloproteinase-1 Genetic Polymorphism in Breast Cancer in Taiwanese. (2016 Jul)Su CHAnticancer Res
18097620Association of polymorphisms of ABCA1 and ROS1 with hypertension in Japanese individuals. (2008 Jan)Yamada YInt J Mol Med
19147396Gene expression in human oral squamous cell carcinoma is influenced by risk factor exposure. (2009 Aug)Cheong SCOral Oncol
26197083MMP, VEGF and TIMP as prognostic factors in recurring bladder cancer. (2015 Dec)Wieczorek EClin Biochem
26439471Genetic polymorphisms of matrix metalloproteinases and protein levels in chronic obstructive pulmonary disease in a Mexican population. (2015)Hernandez-Montoya JBiomark Med
22993337Association of matrix metalloproteinase-1 polymorphisms with risk of COPD and lung cancer and survival in lung cancer. (2012 Sep)Enewold LAnticancer Res
19843588Polymorphisms in the promoter regions of matrix metalloproteinases 1 and 3 and cancer risk: a meta-analysis of 50 case-control studies. (2010 Jan)Peng BMutagenesis