Gene info: ID 4477

SNP ID	Position	Alleles	Trait	Variation Type
rs17178655	chr10:46034023 (GRCh38.p7)	C>T	nicotine dependence	SNV(Single Nucleotide Variation)

Probe	Locus(GRCh37)	Gene	Region	p-val	Trait	PubMed ID
cg00807366	chr10:51553061	MSMB	Gene body	4.539e-4	Alcohol use disorders	26763658

Gene Symbol	Pearson Correlation Coefficient
KLK2	0.958
KLK3	0.95
PRG3	0.689
CRISP3	0.669
TGM4	0.669
OR5B3	0.665
MMP7	0.661
BSX	0.659
ACPP	0.654
TMPRSS2	0.648

Gene Symbol	Pearson Correlation Coefficient
SMN2	-0.157
GPR89B	-0.154
PRKXP1	-0.153
CEP112	-0.148
SLC3A1	-0.146
TRPC5OS	-0.141
NOMO3	-0.14
SLC7A6OS	-0.137
ZNF534	-0.137
WDR93	-0.136

DrugBank
CTD

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C517232	1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane	"1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane results in increased expression of MSMB mRNA"	27473015
C517232	1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane	"AR protein affects the reaction [1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane results in increased expression of MSMB mRNA]"	27473015
C036423	1-aminomethylphosphonic acid	[Herbicides co-treated with 1-aminomethylphosphonic acid] results in increased expression of MSMB mRNA	20566314
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of MSMB mRNA"	19114083
C547124	2,3-dibromopropyl-2,4,6-tribromophenyl ether	"2,3-dibromopropyl-2,4,6-tribromophenyl ether analog results in decreased expression of MSMB mRNA"	25454221
C547124	2,3-dibromopropyl-2,4,6-tribromophenyl ether	"2,3-dibromopropyl-2,4,6-tribromophenyl ether results in decreased expression of MSMB mRNA"	25454221
C549543	3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid	3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid results in decreased expression of MSMB mRNA	25716159
D000082	Acetaminophen	Acetaminophen results in increased expression of MSMB mRNA	22230336
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of MSMB mRNA	22100608
D016604	Aflatoxin B1	Aflatoxin B1 results in increased methylation of MSMB gene	27153756
C000610085	allyl 2,4,6-tribromophenyl ether	"allyl 2,4,6-tribromophenyl ether results in decreased expression of MSMB mRNA"	25454221
D013196	Dihydrotestosterone	AR protein affects the reaction [Dihydrotestosterone results in increased expression of MSMB mRNA]	27473015
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased expression of MSMB mRNA	25454221\|2747301
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of MSMB mRNA	16483693
D000728	Androgens	Androgens binds to MSMB protein	3940634
D001542	Benomyl	Benomyl results in increased expression of MSMB mRNA	15885261
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of MSMB mRNA	21871943
D001564	Benzo(a)pyrene	AHR protein affects the reaction [Benzo(a)pyrene affects the expression of MSMB mRNA]	22228805
D001564	Benzo(a)pyrene	Benzo(a)pyrene binds to MSMB protein	3940634
D004958	Estradiol	EGF protein inhibits the reaction [Estradiol results in increased expression of MSMB mRNA]	24758408
D004958	Estradiol	Estradiol results in decreased expression of MSMB mRNA	21185374
D004958	Estradiol	Estradiol results in increased expression of MSMB mRNA	23019147\|2475840
D004958	Estradiol	Estradiol results in increased expression of MSMB mRNA	17010207
C006780	bisphenol A	bisphenol A results in decreased expression of MSMB mRNA	25181051
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in decreased expression of MSMB mRNA	18804290
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of MSMB mRNA	18804290
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in increased expression of MSMB mRNA	18804290
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in decreased expression of MSMB mRNA	23914054
D003907	Dexamethasone	[Dexamethasone co-treated with Genistein] results in increased expression of MSMB mRNA	25136773
D003907	Dexamethasone	Dexamethasone promotes the reaction [Genistein results in increased expression of MSMB mRNA]	25136773
D003907	Dexamethasone	Dexamethasone results in increased expression of MSMB mRNA	25136773
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of MSMB mRNA	15885261
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of MSMB mRNA	19371625
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of MSMB mRNA	17010207
D004961	Estramustine	Estramustine binds to MSMB protein	3940634
D015025	Zearalenone	Zearalenone results in increased expression of MSMB mRNA	19371625
C000499	ferric oxide	ferric oxide affects the expression of MSMB mRNA	28077287
D005419	Flavonoids	Flavonoids results in increased expression of MSMB mRNA	18035473
D005480	Flurbiprofen	Flurbiprofen results in increased expression of MSMB mRNA	16949054
D005485	Flutamide	Flutamide results in increased expression of MSMB mRNA	15885261
D019833	Genistein	[Dexamethasone co-treated with Genistein] results in increased expression of MSMB mRNA	25136773
D019833	Genistein	Dexamethasone promotes the reaction [Genistein results in increased expression of MSMB mRNA]	25136773
D019833	Genistein	Genistein results in increased expression of MSMB mRNA	19371625\|2513677
D006540	Herbicides	[Herbicides co-treated with 1-aminomethylphosphonic acid] results in increased expression of MSMB mRNA	20566314
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of MSMB mRNA	20044591
D008748	Methylcholanthrene	Methylcholanthrene promotes the reaction [AHR protein binds to MSMB promoter]	20348232
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of MSMB mRNA	20348232
D008748	Methylcholanthrene	Methylcholanthrene binds to MSMB protein	3940634
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of MSMB mRNA	27544571
C029938	nickel sulfate	nickel sulfate results in decreased expression of MSMB mRNA	18651567
C474055	octylphenol	octylphenol results in increased expression of MSMB mRNA	17010207
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in decreased expression of MSMB mRNA	23948077
C046012	pentanal	pentanal results in decreased expression of MSMB mRNA	26079696
C101814	perfluoro-n-undecanoic acid	perfluoro-n-undecanoic acid results in increased expression of MSMB mRNA	23602845
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased expression of MSMB mRNA	18804290
C009007	potassium persulfate	potassium persulfate results in increased expression of MSMB protein	20815409
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA]	14699072
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride affects the expression of MSMB mRNA	14699072
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA	19059307
D015474	Isotretinoin	Isotretinoin results in increased expression of MSMB mRNA	20436886
D012822	Silicon Dioxide	Silicon Dioxide analog results in decreased expression of MSMB mRNA	25895662
C017947	sodium arsenite	sodium arsenite affects the methylation of MSMB gene	28589171
C017947	sodium arsenite	sodium arsenite results in decreased expression of MSMB mRNA	25879800
D013629	Tamoxifen	[Tamoxifen co-treated with ESR1 protein] results in increased expression of MSMB mRNA	19059307
D013739	Testosterone	Testosterone affects the expression of MSMB mRNA	17003280
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of MSMB mRNA	19574409
D013749	Tetrachlorodibenzodioxin	AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MSMB mRNA]	12151645
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of MSMB mRNA	12151645\|2353540
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin binds to MSMB protein	3940634
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of MSMB mRNA"	26179874
C025643	vinclozolin	vinclozolin affects the expression of MSMB mRNA	18220299
D024483	Vitamin K 3	Vitamin K 3 affects the expression of MSMB mRNA	20044591

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0003674	molecular_function	-	ND	-
GO:0005515	protein binding	-	IPI	25416956

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005615	extracellular space	-	TAS	7566962
GO:0005634	nucleus	-	TAS	7566962

Gene: MSMB

ANCO-SNPs

DNA Methylation

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Drugs/Compounds

There is no DrugBank record for this gene !

GO/Pathway

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)