Gene: KPRP

448834
C1orf45
keratinocyte proline rich protein
protein-coding
1q21.3
Ensembl:ENSG00000203786 MIM:613260 Vega:OTTHUMG00000012402 UniprotKB:Q5T749
NG_051190.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.461e-1 (AD)  4.972e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SBSN0.805
KRT230.724
ZBED20.719
GPR10.714
DRD30.701
ENTHD10.7
GPR1010.69
C6orf1320.686
CHAT0.681
SAG0.681

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NXPH3-0.365
SLC17A7-0.362
NANOS3-0.359
GALNT9-0.352
NEUROD2-0.34
SOHLH1-0.333
SEMA7A-0.332
EMX1-0.319
PVALB-0.315
IGSF21-0.314

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D020106AcrylamideAcrylamide results in increased expression of KPRP mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of KPRP mRNA19770486
C006780bisphenol Abisphenol A results in decreased expression of KPRP mRNA25181051
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of KPRP mRNA"22485181
D019833GenisteinESR1 promotes the reaction [Genistein results in decreased expression of KPRP protein]20884965
D019833GenisteinGenistein results in decreased expression of KPRP protein20884965
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of KPRP mRNA"24972896
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of KPRP mRNA23152189
C009495titanium dioxidetitanium dioxide results in increased expression of KPRP mRNA23409001

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI27107012  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IEA-  
GO:0070062extracellular exosome-HDA19056867  19199708  20458337  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28814982Cord blood DNA methylation and adiposity measures in early and mid-childhood. (2017)Kresovich JKClin Epigenetics