Gene info: ID 4616

Gene: GADD45B

GENE ID: 4616

Synonyms: GADD45BETA|MYD118

Description: growth arrest and DNA damage inducible beta

Gene type: protein-coding

Location: 19p13.3

dbXrefs: Ensembl:ENSG00000099860 MIM:604948 Vega:OTTHUMG00000180434 UniprotKB:O75293

RefSeq: NC_000019.10

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND|AD

# Publications: 2

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 9.107e-1 (AD) 4.606e-3 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
CDKN1A	0.896
ZFP36	0.865
CEBPD	0.863
ARID5A	0.862
CSRNP1	0.86
MAFF	0.853
SOCS3	0.846
YBX3	0.831
EMP1	0.831
MT1A	0.828

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
NEUROD6	-0.411
CASC15	-0.4
ABCC12	-0.378
HAPLN1	-0.372
CALHM1	-0.367
LHX6	-0.365
PPEF1	-0.364
KIT	-0.364
XKR4	-0.356
IGF1	-0.349

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [GADD45B protein binds to CYP2B10 promoter]"	23684557
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GADD45B mRNA"	19850644\|2135444
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GADD45B protein"	23684557
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"NR1I3 protein promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GADD45B mRNA]"	19850644\|2269881
C051246	1-methylanthracene	[1-methylanthracene co-treated with fluoranthene] results in increased expression of GADD45B mRNA	28329830
C029141	2,2,5,7,8-pentamethyl-1-hydroxychroman	"2,2,5,7,8-pentamethyl-1-hydroxychroman results in increased expression of GADD45B mRNA"	21920950
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of GADD45B mRNA"	19114083
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran affects the expression of GADD45B mRNA"	18343893
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of GADD45B mRNA]"	21851831
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of GADD45B mRNA"	20005886\|2185183
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"Tetrachlorodibenzodioxin promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of GADD45B mRNA]"	21851831
C029955	2-nitrotoluene	2-nitrotoluene results in increased expression of GADD45B mRNA	15618236
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C517041	(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)	"(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in increased expression of GADD45B mRNA"	19561079
C477187	5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole	"5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole affects the expression of GADD45B mRNA"	22745752
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C553817	7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one	"7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in increased expression of GADD45B mRNA"	19936915
C020738	9,10-dihydro-9,10-dihydroxybenzo(a)pyrene	"9,10-dihydro-9,10-dihydroxybenzo(a)pyrene results in increased expression of GADD45B mRNA"	26238291
D000082	Acetaminophen	Acetaminophen results in increased expression of GADD45B mRNA	21420995
D000082	Acetaminophen	Acetaminophen affects the expression of GADD45B mRNA	17562736
D000082	Acetaminophen	Acetaminophen results in increased expression of GADD45B mRNA	15618236
D000171	Acrolein	Acrolein results in increased expression of GADD45B mRNA	20015449
D000171	Acrolein	Acrolein results in increased expression of GADD45B protein	20015449
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of GADD45B mRNA	21641981\|2715375
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of GADD45B mRNA	19770486
C430898	AGN 194204	AGN 194204 results in decreased expression of GADD45B mRNA	16339527
D000395	Air Pollutants, Occupational	"Air Pollutants, Occupational results in increased expression of GADD45B mRNA"	23195993
D000732	Androstanols	Androstanols inhibits the reaction [DDT results in increased expression of GADD45B mRNA]	23684557
D018501	Antirheumatic Agents	Antirheumatic Agents results in decreased expression of GADD45B mRNA	24449571
D001151	Arsenic	Arsenic results in decreased expression of GADD45B mRNA	16835338
C050510	arsenic trichloride	arsenic trichloride results in increased expression of GADD45B mRNA	16283526
C050510	arsenic trichloride	IKBKB affects the reaction [arsenic trichloride results in increased expression of GADD45B mRNA]	16283526
C006632	arsenic trioxide	arsenic trioxide results in increased expression of GADD45B mRNA	25258189
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of GADD45B mRNA"	18687144\|2535159
D001205	Ascorbic Acid	[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA	18544905
D001374	Azacitidine	Azacitidine promotes the reaction [Depsipeptides results in increased expression of GADD45B]	18225533
D001379	Azathioprine	Azathioprine results in increased expression of GADD45B mRNA	22623647
D001554	Benzene	Benzene results in decreased expression of GADD45B mRNA	15120971\|1512265
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GADD45B mRNA	18164116
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of GADD45B mRNA	20064835\|2010694
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of GADD45B mRNA	19770486
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of GADD45B mRNA	22228805
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of GADD45B mRNA"	19150397\|2038263
D004958	Estradiol	Estradiol results in decreased expression of GADD45B mRNA	19167446
D004958	Estradiol	Estradiol promotes the reaction [GADD45B protein binds to CYP2B10 promoter]	23684557
D004958	Estradiol	Estradiol results in increased expression of GADD45B mRNA	23684557
D004958	Estradiol	Estradiol results in increased expression of GADD45B protein	23684557
D001663	Bilirubin	Bilirubin results in increased expression of GADD45B mRNA	20196124
C006780	bisphenol A	bisphenol A results in decreased expression of GADD45B mRNA	25047013\|2768578
C006780	bisphenol A	bisphenol A results in decreased expression of GADD45B mRNA	25385582
C006780	bisphenol A	bisphenol A results in increased expression of GADD45B mRNA	25181051\|2714399
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide results in increased expression of GADD45B mRNA	24247028
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide results in increased expression of GADD45B mRNA	22434021
D000069286	Bortezomib	Bortezomib results in increased expression of GADD45B mRNA	15509775\|1789588
D000069286	Bortezomib	Bortezomib inhibits the reaction [lipopolysaccharide A results in increased expression of GADD45B mRNA]	15797874
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide affects the expression of GADD45B mRNA	23410634
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in decreased expression of GADD45B mRNA	15336504
D002104	Cadmium	Cadmium affects the expression of GADD45B mRNA	22562489
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of GADD45B mRNA	27375191
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of GADD45B mRNA	19013231
D000074262	Canola Oil	Canola Oil metabolite results in decreased expression of GADD45B mRNA	27363782
D000074262	Canola Oil	Starch analog inhibits the reaction [Canola Oil metabolite results in decreased expression of GADD45B mRNA]	27363782
D002220	Carbamazepine	Carbamazepine affects the expression of GADD45B mRNA	25979313
D012721	Carbaryl	Carbaryl results in decreased expression of GADD45B mRNA	27829164
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of GADD45B mRNA	17484886
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of GADD45B mRNA	15797874
D002251	Carbon Tetrachloride	PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of GADD45B mRNA]	18038451
C099555	CD 437	CD 437 results in increased expression of GADD45B mRNA	17474084
D020245	p-Chloromercuribenzoic Acid	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C100187	chloropicrin	chloropicrin results in increased expression of GADD45B mRNA	26352163
D004390	Chlorpyrifos	[Copper co-treated with Chlorpyrifos] results in decreased expression of GADD45B mRNA	21356183
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of GADD45B	20938992
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GADD45B gene	20938992
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of GADD45B mRNA	20938992
C074702	chromium hexavalent ion	chromium hexavalent ion results in increased expression of GADD45B mRNA	27793765
C043561	chrysin	chrysin results in increased expression of GADD45B mRNA	18331776
C043561	chrysin	chrysin results in increased expression of GADD45B protein	18331776
D002953	Citrinin	Citrinin results in increased expression of GADD45B mRNA	19361540
D002953	Citrinin	U 0126 inhibits the reaction [Citrinin results in increased expression of GADD45B mRNA]	19361540
D002994	Clofibrate	Clofibrate results in increased expression of GADD45B mRNA	23811191
D002994	Clofibrate	Clofibrate results in decreased expression of GADD45B mRNA	22008536
D003078	Colchicine	Colchicine results in increased expression of GADD45B mRNA	20624997
D003300	Copper	[Copper co-treated with Chlorpyrifos] results in decreased expression of GADD45B mRNA	21356183
D003300	Copper	Copper results in decreased expression of GADD45B mRNA	21356183
D003300	Copper	[Disulfiram binds to Copper] which results in decreased expression of GADD45B mRNA	24690739
D003300	Copper	[NSC 689534 binds to Copper] which results in increased expression of GADD45B mRNA	20971185
D019327	Copper Sulfate	Copper Sulfate results in increased expression of GADD45B mRNA	19549813
C030973	cupric oxide	cupric oxide results in increased expression of GADD45B mRNA	22077320
C030973	cupric oxide	cupric oxide results in increased expression of GADD45B protein	22077320
C030973	cupric oxide	GADD45B protein results in decreased susceptibility to cupric oxide	22077320
D003471	Cuprizone	Cuprizone results in increased expression of GADD45B mRNA	27523638
D016572	Cyclosporine	Cyclosporine results in decreased expression of GADD45B mRNA	27989131
D016572	Cyclosporine	Cyclosporine results in increased expression of GADD45B mRNA	20106945\|2556210
D016572	Cyclosporine	Cyclosporine results in decreased expression of GADD45B mRNA	19770486
C089595	cylindrospermopsin	cylindrospermopsin results in increased expression of GADD45B mRNA	23726867\|2492166
C093628	cyproconazole	cyproconazole results in increased expression of GADD45B mRNA	17557908\|2233456
C093628	cyproconazole	NR1I3 protein mutant form inhibits the reaction [cyproconazole results in increased expression of GADD45B mRNA]	17557908
D003634	DDT	Androstanols inhibits the reaction [DDT results in increased expression of GADD45B mRNA]	23684557
D003634	DDT	DDT promotes the reaction [GADD45B protein binds to CYP2B10 promoter]	23684557
D003634	DDT	DDT results in increased expression of GADD45B mRNA	23684557
D003634	DDT	DDT results in increased expression of GADD45B protein	23684557
C014347	decitabine	decitabine affects the expression of GADD45B mRNA	23300844
D047630	Depsipeptides	Azacitidine promotes the reaction [Depsipeptides results in increased expression of GADD45B]	18225533
D047630	Depsipeptides	Depsipeptides results in increased expression of GADD45B	18225533
D003907	Dexamethasone	Dexamethasone inhibits the reaction [lipopolysaccharide A results in increased expression of GADD45B mRNA]	15797874
D003907	Dexamethasone	Dexamethasone results in increased expression of GADD45B mRNA	20032058
D003907	Dexamethasone	Testosterone inhibits the reaction [Dexamethasone results in increased expression of GADD45B mRNA]	20032058
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of GADD45B mRNA	17361019\|2126653
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of GADD45B mRNA	21266533
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in increased expression of GADD45B mRNA	28962523
D002945	Cisplatin	Cisplatin affects the expression of GADD45B mRNA	23300844
D002945	Cisplatin	Cisplatin promotes the reaction [jinfukang results in decreased expression of GADD45B mRNA]	27392435
D002945	Cisplatin	Cisplatin results in decreased expression of GADD45B mRNA	27392435
D002945	Cisplatin	jinfukang promotes the reaction [Cisplatin results in decreased expression of GADD45B mRNA]	27392435
C000944	dicrotophos	dicrotophos results in decreased expression of GADD45B mRNA	28302478
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of GADD45B mRNA	19850644
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of GADD45B mRNA	17942915
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of GADD45B mRNA	18691550\|1910086
D004052	Diethylnitrosamine	IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of GADD45B mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of GADD45B mRNA]	18691550
D004052	Diethylnitrosamine	MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of GADD45B mRNA]	17942915
D004052	Diethylnitrosamine	[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA	18544905
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GADD45B mRNA	18164116
D004052	Diethylnitrosamine	[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA	18253720
D004052	Diethylnitrosamine	[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GADD45B mRNA	22129741
D002117	Calcitriol	Calcitriol results in increased expression of GADD45B mRNA	21592394
D002117	Calcitriol	[Testosterone co-treated with Calcitriol] results in increased expression of GADD45B mRNA	21592394
C062856	dimethylarsine	dimethylarsine analog results in increased expression of GADD45B mRNA	22354777
D004147	Dioxins	Dioxins affects the expression of GADD45B mRNA	20463971
D004221	Disulfiram	[Disulfiram binds to Copper] which results in decreased expression of GADD45B mRNA	24690739
D004317	Doxorubicin	Doxorubicin results in increased expression of GADD45B mRNA	25896364
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in increased expression of GADD45B mRNA"	23811387
C118739	entinostat	entinostat results in increased expression of GADD45B mRNA	26272509\|2718838
C118739	entinostat	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C109476	epoxiconazole	epoxiconazole results in increased expression of GADD45B mRNA	22334560\|2397080
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of GADD45B mRNA	17555576
D004997	Ethinyl Estradiol	Ethinyl Estradiol inhibits the reaction [IL1B protein results in increased expression of GADD45B mRNA]	12072388
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of GADD45B mRNA	17942748
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GADD45B mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of GADD45B mRNA	29097150
D005020	Ethyl Methanesulfonate	Ethyl Methanesulfonate results in decreased expression of GADD45B mRNA	23649840
D005038	Ethylnitrosourea	Ethylnitrosourea results in increased expression of GADD45B mRNA	19100860
D005054	Eugenol	Eugenol results in increased expression of GADD45B mRNA	15618236
D011345	Fenofibrate	[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA	18253720
C000499	ferric oxide	ferric oxide analog results in increased expression of GADD45B mRNA	25086211
C082360	fipronil	fipronil results in increased expression of GADD45B mRNA	23962444
C007738	fluoranthene	[1-methylanthracene co-treated with fluoranthene] results in increased expression of GADD45B mRNA	28329830
D005472	Fluorouracil	GADD45B protein results in decreased susceptibility to Fluorouracil	17711513
D005472	Fluorouracil	IFNG protein inhibits the reaction [GADD45B protein results in decreased susceptibility to Fluorouracil]	17711513
D005472	Fluorouracil	GADD45B protein affects the susceptibility to Fluorouracil	16732331
C065180	fluvastatin	[zoledronic acid co-treated with fluvastatin] results in increased expression of GADD45B mRNA	16996129
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of GADD45B	20938992
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GADD45B gene	20938992
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of GADD45B mRNA	20938992
D005557	Formaldehyde	Formaldehyde results in increased expression of GADD45B mRNA	20655997\|2341626
C546771	gardiquimod	gardiquimod results in increased expression of GADD45B mRNA	28003376
C546771	gardiquimod	Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of GADD45B mRNA]	28003376
C071834	glycidamide	glycidamide results in decreased expression of GADD45B mRNA	17822822
D006118	Griseofulvin	Griseofulvin affects the expression of GADD45B mRNA	12735108
D017313	Fenretinide	Fenretinide results in increased expression of GADD45B mRNA	28973697
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of GADD45B mRNA	23410634
D006997	Hypochlorous Acid	Hypochlorous Acid results in increased expression of GADD45B mRNA	19376150
C492448	ICG 001	ICG 001 results in increased expression of GADD45B mRNA	26191083
C016517	indole-3-carbinol	indole-3-carbinol affects the expression of GADD45B mRNA	21396975
C016517	indole-3-carbinol	[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GADD45B mRNA	22129741
D007213	Indomethacin	Indomethacin results in increased expression of GADD45B mRNA	16984733
C544151	jinfukang	Cisplatin promotes the reaction [jinfukang results in decreased expression of GADD45B mRNA]	27392435
C544151	jinfukang	jinfukang promotes the reaction [Cisplatin results in decreased expression of GADD45B mRNA]	27392435
C544151	jinfukang	jinfukang results in decreased expression of GADD45B mRNA	27392435
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in increased expression of GADD45B mRNA	24796395\|2743299
C410337	K 7174	K 7174 results in increased expression of GADD45B mRNA	24086573
C006552	kaempferol	kaempferol results in increased expression of GADD45B mRNA	18331776
C006552	kaempferol	kaempferol results in increased expression of GADD45B protein	18331776
D007608	Kainic Acid	Kainic Acid results in decreased expression of GADD45B mRNA	17997037
C119620	kenpaullone	kenpaullone results in decreased expression of GADD45B mRNA	17993264
C011890	kojic acid	[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA	18544905
C045463	leflunomide	leflunomide results in increased expression of GADD45B mRNA	28988120
C082161	lipopolysaccharide A	Bortezomib inhibits the reaction [lipopolysaccharide A results in increased expression of GADD45B mRNA]	15797874
C082161	lipopolysaccharide A	Dexamethasone inhibits the reaction [lipopolysaccharide A results in increased expression of GADD45B mRNA]	15797874
C082161	lipopolysaccharide A	lipopolysaccharide A results in increased expression of GADD45B mRNA	15797874
C082161	lipopolysaccharide A	Thalidomide inhibits the reaction [lipopolysaccharide A results in increased expression of GADD45B mRNA]	15797874
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of GADD45B mRNA	15860229
D047311	Luteolin	Luteolin results in increased expression of GADD45B mRNA	18331776
D047311	Luteolin	Luteolin results in increased expression of GADD45B protein	18331776
D058185	Magnetite Nanoparticles	[Succimer binds to Magnetite Nanoparticles] which results in increased expression of GADD45B mRNA	21641980
C042720	mercuric bromide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
D008694	Methamphetamine	[Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA	19564919
D008694	Methamphetamine	Methamphetamine results in increased expression of GADD45B mRNA	19564919
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of GADD45B	20938992
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GADD45B gene	20938992
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of GADD45B mRNA	20938992
D008727	Methotrexate	Methotrexate results in increased expression of GADD45B mRNA	21678067
C005223	methyleugenol	methyleugenol results in increased expression of GADD45B mRNA	15618236
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of GADD45B mRNA	28001369
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of GADD45B mRNA	20061341
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of GADD45B mRNA	22129749
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in increased expression of GADD45B mRNA	23649840
D015655	1-Methyl-4-phenylpyridinium	1-Methyl-4-phenylpyridinium results in increased expression of GADD45B mRNA	25234470
D008777	Methyltestosterone	Methyltestosterone results in increased expression of GADD45B mRNA	29191790
C583365	N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of GADD45B mRNA"	29244179
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of GADD45B mRNA"	25620056
D009285	Naphthoquinones	Naphthoquinones results in increased expression of GADD45B mRNA	23811387
D019829	Nevirapine	Nevirapine results in increased expression of GADD45B mRNA	23947594
D009532	Nickel	Nickel results in increased expression of GADD45B mRNA	23195993\|2476865
D009532	Nickel	Nickel results in decreased expression of GADD45B mRNA	24084258
C022838	nickel chloride	nickel chloride affects the expression of GADD45B mRNA	22546817
C028007	nickel monoxide	nickel monoxide results in decreased expression of GADD45B mRNA	19167457
C558013	NSC 689534	[NSC 689534 binds to Copper] which results in increased expression of GADD45B mRNA	20971185
C016340	o,p'-DDT	"o,p'-DDT affects the expression of GADD45B mRNA"	18925944
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in increased expression of GADD45B mRNA	25729387
D010076	Oxazepam	Oxazepam results in increased expression of GADD45B mRNA	12727805\|1561823
D010076	Oxazepam	Oxazepam results in increased expression of GADD45B protein	12727805
D010081	Oxazolone	Oxazolone results in increased expression of GADD45B mRNA	11379042
C472349	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of GADD45B mRNA	17655762
C472349	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of GADD45B mRNA]	17655762
C472349	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of GADD45B mRNA]	17655762
C472349	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine	Particulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of GADD45B mRNA]	17655762
C472349	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine	Vehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of GADD45B mRNA]	17655762
D010100	Oxygen	Oxygen deficiency results in increased expression of GADD45B mRNA	26516004
C496932	panobinostat	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C496932	panobinostat	panobinostat results in increased expression of GADD45B mRNA	26272509
D010269	Paraquat	Paraquat results in increased expression of GADD45B mRNA	12595580\|1524699
D052638	Particulate Matter	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of GADD45B mRNA]	17655762
D052638	Particulate Matter	Particulate Matter affects the expression of GADD45B mRNA	17655762
D052638	Particulate Matter	Particulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of GADD45B mRNA]	17655762
D052638	Particulate Matter	Particulate Matter results in decreased expression of GADD45B mRNA	28412507
D052638	Particulate Matter	Particulate Matter results in increased expression of GADD45B mRNA	21703343
C568608	PCI 5002	[PCI 5002 co-treated with Zinc] results in increased expression of GADD45B mRNA	18593933
C008776	pelargonic acid	pelargonic acid results in increased expression of GADD45B mRNA	11379042
D010457	Peptidoglycan	Peptidoglycan results in increased expression of GADD45B mRNA	15860229
C036567	perfluorodecanoic acid	perfluorodecanoic acid results in increased expression of GADD45B mRNA	21984479
C522391	perfluorododecanoic acid	perfluorododecanoic acid results in increased expression of GADD45B mRNA	23567314
C101815	perfluoro-n-heptanoic acid	perfluoro-n-heptanoic acid results in decreased expression of GADD45B mRNA	23567314
C101816	perfluoro-n-nonanoic acid	perfluoro-n-nonanoic acid results in increased expression of GADD45B mRNA	21984479
C101814	perfluoro-n-undecanoic acid	perfluoro-n-undecanoic acid results in increased expression of GADD45B mRNA	23567314
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of GADD45B mRNA	18467677
C023036	perfluorooctanoic acid	PPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of GADD45B mRNA]	18467677
C539933	pevonedistat	pevonedistat affects the expression of GADD45B mRNA	24634471
D010634	Phenobarbital	NR1I3 protein affects the reaction [Phenobarbital results in increased expression of GADD45B mRNA]	19482888
D010634	Phenobarbital	NR1I3 protein mutant form inhibits the reaction [Phenobarbital results in increased expression of GADD45B mRNA]	17557908
D010634	Phenobarbital	NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of GADD45B mRNA]	19482888\|1985064
D010634	Phenobarbital	Phenobarbital results in increased expression of GADD45B mRNA	17557908\|1927001
D010634	Phenobarbital	Phenobarbital results in increased expression of GADD45B mRNA	22008536\|2514565
D010662	Phenylmercuric Acetate	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
D010662	Phenylmercuric Acetate	Phenylmercuric Acetate results in increased expression of GADD45B mRNA	26272509
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GADD45B mRNA	19710929
C006253	pirinixic acid	[pirinixic acid co-treated with PPARA] results in increased expression of GADD45B mRNA	20813756
C006253	pirinixic acid	pirinixic acid results in increased expression of GADD45B mRNA	12727805\|1561823
C006253	pirinixic acid	pirinixic acid results in increased expression of GADD45B protein	12727805
C006253	pirinixic acid	PPARA protein promotes the reaction [pirinixic acid results in decreased expression of GADD45B mRNA]	19850644
C006253	pirinixic acid	PPARA protein promotes the reaction [pirinixic acid results in increased expression of GADD45B mRNA]	18467677\|2005976
D010938	Plant Oils	Plant Oils results in increased expression of GADD45B mRNA	23370395
C060540	polyhexamethyleneguanidine	polyhexamethyleneguanidine results in increased expression of GADD45B mRNA	24583197
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of GADD45B mRNA	27413110\|2890350
C045950	propiconazole	propiconazole results in increased expression of GADD45B mRNA	21278054\|2233456
D011441	Propylthiouracil	Propylthiouracil results in decreased expression of GADD45B mRNA	24780913
D047428	Protein Kinase Inhibitors	Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of GADD45B mRNA]	28003376
C513428	pyrachlostrobin	pyrachlostrobin results in increased expression of GADD45B mRNA	27029645
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [sorafenib results in increased expression of GADD45B mRNA]	21062976
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [sorafenib results in increased expression of GADD45B protein]	21062976
D011794	Quercetin	Quercetin results in increased expression of GADD45B mRNA	18331776\|2163298
D011794	Quercetin	Quercetin results in increased expression of GADD45B protein	18331776
C031389	resorcinol	resorcinol results in decreased expression of GADD45B mRNA	22623647
C059514	resveratrol	resveratrol results in increased expression of GADD45B mRNA	23525482
C059514	resveratrol	[resveratrol co-treated with Streptozocin] results in increased expression of GADD45B mRNA	25905778
C059514	resveratrol	resveratrol results in increased expression of GADD45B mRNA	20797428\|2590577
D012293	Rifampin	NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA]	21127053
C534628	SCH 23390	[Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA	19564919
D020280	Sertraline	Sertraline results in increased expression of GADD45B mRNA	24865413
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of GADD45B mRNA	25351596
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of GADD45B mRNA	19073995\|2322117
D012834	Silver	Silver results in increased expression of GADD45B mRNA	26014281\|2895954
D012906	Smoke	Smoke results in increased expression of GADD45B protein	20015449
C009277	sodium arsenate	sodium arsenate results in increased expression of GADD45B mRNA	16882884
C017947	sodium arsenite	sodium arsenite results in increased expression of GADD45B mRNA	12760830\|2235477
C017947	sodium arsenite	sodium arsenite results in increased expression of GADD45B mRNA	15797874\|1601473
D012999	Soman	Soman results in increased expression of GADD45B mRNA	19281266
C471405	sorafenib	GADD45B protein results in increased susceptibility to sorafenib	21062976
C471405	sorafenib	pyrazolanthrone inhibits the reaction [sorafenib results in increased expression of GADD45B mRNA]	21062976
C471405	sorafenib	pyrazolanthrone inhibits the reaction [sorafenib results in increased expression of GADD45B protein]	21062976
C471405	sorafenib	sorafenib promotes the reaction [JUN protein binds to GADD45B promoter]	21062976
C471405	sorafenib	sorafenib results in increased expression of and results in increased localization of GADD45B protein	21062976
C471405	sorafenib	sorafenib results in increased expression of GADD45B mRNA	21062976
D013213	Starch	Starch analog inhibits the reaction [Canola Oil metabolite results in decreased expression of GADD45B mRNA]	27363782
D013311	Streptozocin	[resveratrol co-treated with Streptozocin] results in increased expression of GADD45B mRNA	25905778
D004113	Succimer	[Succimer binds to Magnetite Nanoparticles] which results in increased expression of GADD45B mRNA	21641980
D012460	Sulfasalazine	Sulfasalazine results in decreased expression of GADD45B mRNA	15633128
C446685	systhane	systhane results in increased expression of GADD45B mRNA	23970803
C087114	tebuconazole	tebuconazole results in increased expression of GADD45B mRNA	25656644
D013739	Testosterone	[Testosterone co-treated with Calcitriol] results in increased expression of GADD45B mRNA	21592394
D013739	Testosterone	Testosterone results in increased expression of GADD45B mRNA	21592394
D013739	Testosterone	Testosterone inhibits the reaction [Dexamethasone results in increased expression of GADD45B mRNA]	20032058
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of GADD45B mRNA	16443690
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of GADD45B mRNA	20106945\|2163298
D013749	Tetrachlorodibenzodioxin	"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of GADD45B mRNA]"	21851831
D013749	Tetrachlorodibenzodioxin	[NFE2L2 gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of GADD45B mRNA	21846477
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of GADD45B mRNA	18343893\|2157046
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GADD45B mRNA	17942748
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of GADD45B mRNA	25975270
D013749	Tetrachlorodibenzodioxin	"Tetrachlorodibenzodioxin promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of GADD45B mRNA]"	21851831
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GADD45B gene]	28213091
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of GADD45B mRNA	19770486
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of GADD45B mRNA	15800033\|1661135
D013792	Thalidomide	Thalidomide inhibits the reaction [lipopolysaccharide A results in increased expression of GADD45B mRNA]	15797874
D013853	Thioacetamide	Thioacetamide results in increased expression of GADD45B mRNA	23411599
D013893	Thiram	Thiram results in increased expression of GADD45B mRNA	20530235
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of GADD45B mRNA	27404394\|2786577
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in increased expression of GADD45B mRNA	25729387
D019772	Topotecan	Topotecan results in increased expression of GADD45B mRNA	25729387
D014118	Toxins, Biological	"Toxins, Biological affects the expression of GADD45B mRNA"	19682533
C032910	triadimefon	triadimefon results in increased expression of GADD45B mRNA	23970803
C011559	tributyltin	tributyltin results in increased expression of GADD45B mRNA	21683754
D014241	Trichloroethylene	Trichloroethylene results in increased expression of GADD45B mRNA	25549359\|2897337
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GADD45B mRNA"	27188386
C012589	trichostatin A	trichostatin A affects the expression of GADD45B mRNA	28542535
C012589	trichostatin A	trichostatin A results in increased expression of GADD45B mRNA	24935251\|2627250
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of GADD45B mRNA"	26179874
D014415	Tunicamycin	Tunicamycin results in decreased expression of GADD45B mRNA	17127020
C113580	U 0126	U 0126 inhibits the reaction [Citrinin results in increased expression of GADD45B mRNA]	19361540
D014520	Urethane	Urethane results in increased expression of GADD45B mRNA	28818685
D014635	Valproic Acid	Valproic Acid affects the expression of GADD45B mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in increased expression of GADD45B mRNA	23179753\|2438349
D014635	Valproic Acid	Valproic Acid affects the expression of GADD45B mRNA	17292431
D014635	Valproic Acid	Valproic Acid results in increased expression of GADD45B mRNA	15799026
D001335	Vehicle Emissions	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of GADD45B mRNA]	17655762
D001335	Vehicle Emissions	Vehicle Emissions affects the expression of GADD45B mRNA	17655762
D001335	Vehicle Emissions	Vehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of GADD45B mRNA]	17655762
D001335	Vehicle Emissions	Vehicle Emissions results in decreased methylation of GADD45B gene	25560391
D014747	Vinblastine	Vinblastine results in increased expression of GADD45B mRNA	20624997
C025643	vinclozolin	vinclozolin affects the expression of GADD45B mRNA	19015723
D014750	Vincristine	Vincristine results in increased expression of GADD45B mRNA	20624997
D024483	Vitamin K 3	Vitamin K 3 affects the expression of GADD45B mRNA	23410634
D015032	Zinc	[PCI 5002 co-treated with Zinc] results in increased expression of GADD45B mRNA	18593933
D015034	Zinc Oxide	Zinc Oxide results in increased expression of GADD45B protein	21769377
C088658	zoledronic acid	[zoledronic acid co-treated with fluvastatin] results in increased expression of GADD45B mRNA	16996129
C088658	zoledronic acid	zoledronic acid results in increased expression of GADD45B mRNA	20977926

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005515	protein binding	-	IPI	12052864 16256071 25314077

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000185	activation of MAPKKK activity	-	IBA	21873635
GO:0000185	activation of MAPKKK activity	-	IDA	9827804
GO:0000186	activation of MAPKK activity	-	IEA	-
GO:0006469	negative regulation of protein kinase activity	-	IEA	-
GO:0006915	apoptotic process	-	IEA	-
GO:0006950	response to stress	-	IEA	-
GO:0007275	multicellular organism development	-	IEA	-
GO:0030154	cell differentiation	-	IEA	-
GO:0043065	positive regulation of apoptotic process	-	IDA	9827804
GO:0046330	positive regulation of JNK cascade	-	IDA	9827804
GO:0051726	regulation of cell cycle	-	IBA	21873635
GO:1900745	positive regulation of p38MAPK cascade	-	IDA	9827804

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005634	nucleus	-	IBA	21873635
GO:0005634	nucleus	-	IDA	9827804
GO:0005737	cytoplasm	-	IBA	21873635
GO:0005737	cytoplasm	-	IDA	9827804

KEGG ID	KEGG Term
hsa04010	MAPK signaling pathway
hsa04110	Cell cycle
hsa04115	p53 signaling pathway

Reactome ID	Reactome Term	Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
26842245	Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors. (2016 Feb)	Gavin DP	Alcohol Clin Exp Res
26111030	Gadd45b and N-methyl-D-aspartate induced DNA demethylation in postmitotic neurons. (2015)	Gavin DP	Epigenomics