Gene: NFIL3

4783
E4BP4|IL3BP1|NF-IL3A|NFIL3A
nuclear factor, interleukin 3 regulated
protein-coding
9q22.31
Ensembl:ENSG00000165030 MIM:605327 Vega:OTTHUMG00000020209 UniprotKB:Q16649
NC_000009.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.170e-1 (AD)  8.911e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg07084627chr9:94183408NFIL3Promoter1.183e-4Alcohol use disorders26763658
cg13555464chr9:94183343NFIL3Promoter6.440e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
XBP10.844
PIM10.811
ETV60.795
NAMPT0.794
TPST10.776
SHC10.772
CDKN1A0.772
MTHFD20.768
SOD20.768
SOAT10.765

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HES5-0.455
RERGL-0.385
GPR17-0.359
OR4F5-0.346
REM1-0.343
SNX22-0.337
OR4F29-0.337
MUSTN1-0.334
MYLK2-0.316
NEU4-0.316

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0067181,12-benzoperylene"1,12-benzoperylene results in decreased expression of NFIL3 mRNA"26377693
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in decreased expression of NFIL3 mRNA"26377693
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of NFIL3 mRNA"28903501
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of NFIL3 mRNA28329830
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of NFIL3 mRNA"25614096
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of NFIL3 mRNA"19095052
C0291412,2,5,7,8-pentamethyl-1-hydroxychroman"2,2,5,7,8-pentamethyl-1-hydroxychroman results in decreased expression of NFIL3 mRNA"21920950
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NFIL3 mRNA"19167446
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in decreased expression of NFIL3 mRNA]28655636
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in decreased expression of NFIL3 mRNA]28655636
D000082AcetaminophenAcetaminophen results in increased expression of NFIL3 mRNA21420995|2906747
D000082AcetaminophenAcetaminophen affects the expression of NFIL3 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of NFIL3 mRNA11264010
D000111Acetylcysteine[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NFIL3 mRNA22129741
D020106AcrylamideAcrylamide results in increased expression of NFIL3 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of NFIL3 mRNA22100608
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of NFIL3 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of NFIL3 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of NFIL3 mRNA19770486
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in decreased expression of NFIL3 mRNA28522335
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of NFIL3 mRNA21298039
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NFIL3 mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of NFIL3 mRNA24449571
D001151ArsenicArsenic results in increased methylation of NFIL3 promoter21291286
C015001arsenitearsenite affects the expression of NFIL3 mRNA22959463
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of NFIL3 mRNA"18687144
C030935benz(a)anthracenebenz(a)anthracene results in decreased expression of NFIL3 mRNA26377693
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of NFIL3 mRNA27858113
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of NFIL3 mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of NFIL3 mRNA26377693
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NFIL3 mRNA18164116
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of NFIL3 mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of NFIL3 mRNA19770486|2171566
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NFIL3 mRNA21569818
D004958EstradiolEstradiol results in decreased expression of NFIL3 mRNA19167446
D004958EstradiolEstradiol results in increased expression of NFIL3 mRNA20106945
D004958EstradiolEstradiol results in increased expression of NFIL3 mRNA19484750|2521013
C006780bisphenol Abisphenol A affects the methylation of NFIL3 promoter27334623
C006780bisphenol A[bisphenol A co-treated with Genistein] results in decreased methylation of NFIL3 gene28505145
C006780bisphenol Abisphenol A results in increased expression of NFIL3 mRNA25181051
C027561butylbenzyl phthalatebutylbenzyl phthalate results in increased expression of NFIL3 mRNA15728792
D002104CadmiumCadmium results in decreased expression of NFIL3 mRNA23369406
D002104CadmiumCadmium results in increased expression of NFIL3 mRNA24376830
D002104CadmiumCadmium results in decreased expression of NFIL3 mRNA24084258
D002220CarbamazepineCarbamazepine affects the expression of NFIL3 mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of NFIL3 mRNA27339419
D002509CephaloridineCephaloridine results in increased expression of NFIL3 mRNA18500788
D002737ChloropreneChloroprene results in increased expression of NFIL3 mRNA23125180
D002737ChloropreneChloroprene results in decreased expression of NFIL3 mRNA23125180
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NFIL3 gene20938992
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of NFIL3 mRNA27858113
D002994ClofibrateClofibrate results in decreased expression of NFIL3 mRNA17585979
C018021cobaltous chloridecobaltous chloride results in increased expression of NFIL3 mRNA24612858
C018021cobaltous chloridecobaltous chloride results in increased expression of NFIL3 mRNA19376846
C060728cobalt oxidecobalt oxide analog results in increased expression of NFIL3 mRNA24821434
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of NFIL3 mRNA20971185
D019327Copper SulfateCopper Sulfate affects the expression of NFIL3 mRNA19549813
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NFIL3 mRNA"19167446
C030973cupric oxidecupric oxide results in increased expression of NFIL3 mRNA22077320
D016572CyclosporineCyclosporine results in increased expression of NFIL3 mRNA20106945|2556210
C014347decitabinedecitabine affects the expression of NFIL3 mRNA23300844
D003907DexamethasoneDexamethasone results in increased expression of NFIL3 mRNA12782123
D003907DexamethasoneDexamethasone results in increased expression of NFIL3 mRNA22733784
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NFIL3 mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NFIL3 mRNA21266533|2174549
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of NFIL3 mRNA28962523
D002945CisplatinCisplatin affects the expression of NFIL3 mRNA23300844
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of NFIL3 mRNA27392435
D002945CisplatinCisplatin results in increased expression of NFIL3 mRNA27594783
D002945CisplatinCisplatin results in decreased expression of NFIL3 mRNA25270620
D004008DiclofenacDiclofenac results in increased expression of NFIL3 mRNA26934552
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of NFIL3 mRNA26924002
D004041Dietary FatsDietary Fats results in decreased expression of NFIL3 mRNA18042831
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of NFIL3 mRNA15728792
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NFIL3 mRNA18164116
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NFIL3 mRNA22129741
C024629dimethyl phthalatedimethyl phthalate affects the expression of NFIL3 mRNA26924002
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of NFIL3 mRNA"23811387
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NFIL3 mRNA22079256
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of NFIL3 mRNA28329830
C061365flusilazoleflusilazole affects the expression of NFIL3 mRNA21195148
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NFIL3 gene20938992
C069837fullerene C60fullerene C60 results in decreased expression of NFIL3 mRNA19167457
C039281furanfuran results in decreased expression of NFIL3 mRNA25539665|2619464
D019833Genistein[bisphenol A co-treated with Genistein] results in decreased methylation of NFIL3 gene28505145
C409722hexaconazolehexaconazole affects the expression of NFIL3 mRNA21195148
D017313FenretinideFenretinide results in increased expression of NFIL3 mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of NFIL3 mRNA20044591
C492448ICG 001ICG 001 affects the expression of NFIL3 mRNA26191083
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in decreased expression of NFIL3 mRNA"26377693
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NFIL3 mRNA22129741
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NFIL3 mRNA25613284
D007501IronIron deficiency results in increased expression of NFIL3 mRNA20368581
D007545IsoproterenolIsoproterenol results in increased expression of NFIL3 mRNA20003209
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of NFIL3 mRNA27392435
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of NFIL3 protein17337753
C410337K 7174K 7174 results in increased expression of NFIL3 mRNA24086573
D007649KetamineKetamine results in decreased expression of NFIL3 mRNA20080153
C011890kojic acidkojic acid results in increased expression of NFIL3 mRNA16595896
C045463leflunomideleflunomide results in increased expression of NFIL3 mRNA28988120
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of NFIL3 mRNA27339419
D008694Methamphetamine[Methamphetamine co-treated with SCH 23390] results in increased expression of NFIL3 mRNA19564919
D008694MethamphetamineMethamphetamine results in increased expression of NFIL3 mRNA19564919
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NFIL3 gene20938992
D008727MethotrexateMethotrexate results in increased expression of NFIL3 mRNA24657277
D008752Methylene ChlorideMethylene Chloride results in decreased expression of NFIL3 mRNA28392392
C008493methylselenic acidmethylselenic acid affects the expression of NFIL3 mRNA14617803
D016685MitomycinMitomycin results in decreased expression of NFIL3 mRNA25270620
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of NFIL3 mRNA20024957
C517284monomethyl phthalatemonomethyl phthalate affects the expression of NFIL3 mRNA26924002
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of NFIL3 mRNA"29244179
D037742Nanotubes, Carbon"Nanotubes, Carbon analog affects the expression of NFIL3 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of NFIL3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of NFIL3 mRNA"25554681|2562005
D009285NaphthoquinonesNaphthoquinones results in increased expression of NFIL3 mRNA23811387
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of NFIL3 mRNA20551477
C051752nefazodonenefazodone results in decreased expression of NFIL3 mRNA24136188
C022838nickel chloridenickel chloride results in increased expression of NFIL3 mRNA17312168
C022838nickel chloridenickel chloride affects the expression of NFIL3 mRNA22110744
C028007nickel monoxidenickel monoxide results in decreased expression of NFIL3 mRNA19167457
C029938nickel sulfatenickel sulfate results in increased expression of NFIL3 mRNA16780908|1865156
C012655nimesulidenimesulide results in decreased expression of NFIL3 mRNA24136188
D009638NorepinephrineNorepinephrine results in increased expression of NFIL3 mRNA12729908
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of NFIL3 mRNA20971185
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of NFIL3 mRNA17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of NFIL3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of NFIL3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of NFIL3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of NFIL3 mRNA]17655762
D010126OzoneOzone results in increased expression of NFIL3 mRNA17095637|1955522
D000073878Palm OilPalm Oil results in decreased expression of NFIL3 mRNA18042831
D052638Particulate Matter2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in decreased expression of NFIL3 mRNA]28655636
D052638Particulate Matteroxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of NFIL3 mRNA]17655762
D052638Particulate MatterParticulate Matter affects the expression of NFIL3 mRNA17655762
D052638Particulate MatterParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of NFIL3 mRNA]17655762
D052638Particulate MatterParticulate Matter results in decreased expression of NFIL3 mRNA28655636
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of NFIL3 mRNA18593933
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of NFIL3 mRNA19095052
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of NFIL3 mRNA19162173
D010634PhenobarbitalPhenobarbital affects the expression of NFIL3 mRNA19159669
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of NFIL3 mRNA]19482888
D010634PhenobarbitalPhenobarbital affects the expression of NFIL3 mRNA23091169
D010634PhenobarbitalPhenobarbital results in decreased expression of NFIL3 mRNA19270015|1948288
D010656PhenylephrineU 0126 inhibits the reaction [Phenylephrine results in increased expression of NFIL3 mRNA]12729908
C006253pirinixic acidpirinixic acid results in decreased expression of NFIL3 mRNA17426115|2081375
C006253pirinixic acidpirinixic acid results in increased expression of NFIL3 mRNA18445702
D011137PolystyrenesPolystyrenes analog results in increased expression of NFIL3 mRNA25102311
D011137PolystyrenesPolystyrenes results in increased expression of NFIL3 mRNA25102311
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NFIL3 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of NFIL3 mRNA22079256
D011374ProgesteroneProgesterone results in increased expression of NFIL3 mRNA20864642|2179573
D011374ProgesteroneProgesterone results in decreased expression of NFIL317510236
D011794QuercetinQuercetin results in decreased expression of NFIL3 mRNA21632981
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride affects the expression of NFIL3 mRNA14699072
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA19059307
D012406RoxarsoneRoxarsone results in increased expression of NFIL3 mRNA23155029
C534628SCH 23390[Methamphetamine co-treated with SCH 23390] results in increased expression of NFIL3 mRNA19564919
C009250sevofluranesevoflurane affects the expression of NFIL3 mRNA15967596
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of NFIL3 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in decreased expression of NFIL3 mRNA25351596
D012822Silicon DioxideSilicon Dioxide results in increased expression of NFIL3 mRNA19073995
C009277sodium arsenatesodium arsenate results in decreased expression of NFIL3 mRNA21795629
C017947sodium arsenitesodium arsenite affects the methylation of NFIL3 gene28589171
C016104sodium bichromatesodium bichromate results in increased expression of NFIL3 mRNA24612858
D012999SomanSoman results in increased expression of NFIL3 mRNA19281266
D053260SootSoot results in increased expression of NFIL3 mRNA22461453|2655175
D020058StyreneStyrene affects the expression of NFIL3 mRNA28951217
D020058StyreneStyrene results in decreased expression of NFIL3 mRNA28951217
D013467SulindacSulindac results in increased expression of NFIL3 mRNA11906190
D013629TamoxifenTamoxifen affects the expression of NFIL3 mRNA14699072
D013629Tamoxifen[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA19059307
D013629TamoxifenTamoxifen affects the expression of NFIL3 mRNA20937368
D013739TestosteroneTestosterone results in increased expression of NFIL3 mRNA15788153
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NFIL3 mRNA17101203
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of NFIL3 mRNA26377647
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NFIL3 mRNA28922406
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of NFIL3 mRNA19770486|2405805
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NFIL3 mRNA25613284
C009495titanium dioxidetitanium dioxide affects the expression of NFIL3 mRNA27760801
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of NFIL3 mRNA20133372
C024746tobacco tartobacco tar results in decreased expression of NFIL3 mRNA19559774
C483909torcetrapibtorcetrapib results in increased expression of NFIL3 mRNA23228038
C032910triadimefontriadimefon affects the expression of NFIL3 mRNA21195148
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of NFIL3 mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of NFIL3 mRNA"26179874
C057693troglitazonetroglitazone results in increased expression of NFIL3 mRNA19140230
D014415TunicamycinTunicamycin results in increased expression of NFIL3 mRNA17127020
C113580U 0126U 0126 inhibits the reaction [Phenylephrine results in increased expression of NFIL3 mRNA]12729908
C022884undecaneundecane results in increased expression of NFIL3 protein17337753
D014635Valproic AcidValproic Acid results in increased expression of NFIL3 mRNA23179753|2915479
D000068756ValsartanValsartan inhibits the reaction [AGT protein results in increased expression of NFIL3 mRNA]19225232
D001335Vehicle Emissions2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in decreased expression of NFIL3 mRNA]28655636
D001335Vehicle Emissionsoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of NFIL3 mRNA]17655762
D001335Vehicle EmissionsVehicle Emissions affects the expression of NFIL3 mRNA17655762
D001335Vehicle EmissionsVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of NFIL3 mRNA]17655762
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of NFIL3 mRNA28655636
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of NFIL3 gene25560391
C025643vinclozolinvinclozolin results in decreased expression of NFIL3 mRNA23034163
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of NFIL3 mRNA18593933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IDA20093779  
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IEA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IBA21873635  
GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IDA20093779  
GO:0003677DNA binding-TAS1620116  
GO:0003700DNA-binding transcription factor activity-TAS7565758  
GO:0003714transcription corepressor activity-TAS1620116  
GO:0005515protein binding-IPI20102225  21516116  25416956  25609649  
GO:0042802identical protein binding-IPI12805554  20102225  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IMP20093779  
GO:0006355regulation of transcription, DNA-templated-IBA21873635  
GO:0006366transcription by RNA polymerase II-IEA-  
GO:0006955immune response-IEA-  
GO:0007623circadian rhythm-IBA21873635  
GO:0010628positive regulation of gene expression-IEA-  
GO:0071353cellular response to interleukin-4-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-400253Circadian ClockIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28296937Effects of circadian clock genes and health-related behavior on metabolic syndrome in a Taiwanese population: Evidence from association and interaction analysis. (2017)Lin EPLoS One