Gene: NGF

4803
Beta-NGF|HSAN5|NGFB
nerve growth factor
protein-coding
1p13.2
Ensembl:ENSG00000134259 MIM:162030 Vega:OTTHUMG00000011880 UniprotKB:P01138
NG_007944.1
PubMed|SNP Mapped
CD|OD|ND|AD
24   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.582e-1 (AD)  2.920e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10489530chr1:115297059 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg20678800chr1:115857431NGF9.300e-9Smoking27651444

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ST8SIA40.606
TRPC40.588
KCNJ50.57
SUSD30.567
ARHGAP40.564
PTP4A30.558
MAFB0.556
FGD30.546
PLCB20.544
DENND2D0.542

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CABLES1-0.353
SDC4-0.35
MOXD1-0.319
LPAR3-0.317
NWD1-0.316
ATP13A5-0.306
NTSR2-0.303
GABRG1-0.298
SPON1-0.291
EGFR-0.289

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01407ClenbuterolSmall Molecule37148-27-9Approved|InvestigationalTarget
DB05892RI 624BiotechDrug-InvestigationalTarget
DB09221PolaprezincSmall Molecule107667-60-7Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [NGF protein results in increased transport of Calcium]"21981408
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester results in decreased susceptibility to NGF protein"21981408
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dronabinol results in increased expression of NGF protein]12834810
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead acetate results in increased activity of NGF protein]11233754
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased expression of CALCA mRNA]12574409
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased expression of PLA2G4A mRNA]22187434
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased phosphorylation of MAPK1 protein]17324588
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased phosphorylation of MAPK3 protein]17324588
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]17324588
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of NGF protein9733710
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-oneU 0126 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]17324588
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of NGF mRNA"25710175
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dronabinol results in increased expression of NGF protein]12834810
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [methanandamide results in increased expression of NGF protein]12834810
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NGF results in increased localization of TRPV1 protein]16319926
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NGF results in increased phosphorylation of TRPV1 protein]16319926
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased phosphorylation of AKT1 protein]17324588
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of NGF protein21975456
C4624993-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester"3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]"20127836
C0185994-methylcatechol4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein]8195800
C0408109-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2"9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA"22982731
C0408109-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2"Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA]"22982731
D000082AcetaminophenAcetaminophen results in increased expression of NGF mRNA26690555
D000082AcetaminophenAcetaminophen affects the expression of NGF mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of NGF mRNA23472850
D000082AcetaminophenNGF protein affects the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of NTRK1 protein]23472850
D000082AcetaminophenNGF protein affects the susceptibility to Acetaminophen23472850
D000082AcetaminophenAcetaminophen affects the reaction [NGF protein results in increased secretion of Dinoprostone]21811393
D000108AcetylcarnitineAcetylcarnitine inhibits the reaction [Cisplatin results in decreased expression of NGF protein]14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of ARF5 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of ATP5F1B mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of ATP5MC1 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of ATP5PD mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of CHGA mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of COX8B mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of CSNK1D mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of EGR1 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of ID1 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of ID2 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of ID3 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of MGST1 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of PSMB6 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of PTMA mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of PTPRN mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of RPS19 mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of RPS3A mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of VGF mRNA14654561
D000108Acetylcarnitine[Acetylcarnitine co-treated with NGF protein] results in increased expression of YWHAZ mRNA14654561
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of NGF mRNA]23472850
D000111AcetylcysteineAcetylcysteine inhibits the reaction [NGF protein results in increased localization of and results in increased activity of PRKCE protein]18375950
D000111AcetylcysteineAcetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK1 protein]16603213
D000111AcetylcysteineAcetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK3 protein]16603213
D020106AcrylamideDexamethasone inhibits the reaction [NGF protein promotes the reaction [Acrylamide results in increased expression of NEFM protein]]10678756
D020106AcrylamideNGF protein promotes the reaction [Acrylamide results in increased expression of NEFL protein]10678756
D020106AcrylamideNGF protein promotes the reaction [Acrylamide results in increased expression of NEFM protein]10678756
D000242Cyclic AMPNGF protein results in increased abundance of Cyclic AMP6315882
D000242Cyclic AMP[Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA2174743
D000242Cyclic AMPCyclic AMP results in increased expression of NGF mRNA2174743|2853697
D000242Cyclic AMP[Isoproterenol results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA2174743
D000255Adenosine Triphosphate[NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium1374475
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of NGF gene27153756
C412373AG 1879AG 1879 inhibits the reaction [NGF results in increased localization of TRPV1 protein]16319926
C067527aluminum maltolatealuminum maltolate results in decreased expression of NGF mRNA12606298
D000640AmitroleAmitrole affects the activity of NGF protein15935206
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NGF mRNA16483693
D003913DextroamphetamineDextroamphetamine results in decreased expression of NGF protein17434716
D001151ArsenicArsenic results in decreased expression of NGF mRNA23600209
C072763azamethiphosazamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]28385489
C072763azamethiphosazamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]28385489
C072763azamethiphosazamethiphos promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]28385489
C065857beclomethasone 17-monopropionatebeclomethasone 17-monopropionate inhibits the reaction [IL1B protein results in increased secretion of NGF protein]20603167
C065857beclomethasone 17-monopropionatebeclomethasone 17-monopropionate results in decreased secretion of NGF protein20603167
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NGF mRNA20713471
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NGF mRNA"20382639
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NGF mRNA25566086
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeMYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NGF mRNA]25566086
D001599BerberineBerberine inhibits the reaction [Glucose results in decreased expression of NGF protein]23954465
D001599BerberineNFE2L2 mutant form inhibits the reaction [Berberine results in increased expression of NGF protein]23954465
D004958EstradiolEstradiol affects the expression of NGF mRNA23557687
D004958EstradiolEstradiol results in increased expression of NGF protein16436532
D004958EstradiolESR1 protein promotes the reaction [Estradiol results in decreased expression of NGF mRNA]25210133
D004958EstradiolEstradiol results in decreased expression of NGF mRNA25210133
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of NGF mRNA21277368
D004958EstradiolEstradiol results in increased expression of NGF protein15570173
D004958EstradiolProgesterone inhibits the reaction [Estradiol results in increased expression of NGF protein]15570173
D001640BicucullineBicuculline inhibits the reaction [Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]11991087
D001640BicucullineBicuculline inhibits the reaction [Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]11991087
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [NGF results in increased susceptibility to Capsaicin]12815188
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
C006780bisphenol Abisphenol A affects the expression of NGF mRNA25205691
C006780bisphenol Abisphenol A results in increased methylation of NGF promoter27312807
C006780bisphenol Abisphenol A inhibits the reaction [NGF protein results in increased phosphorylation of MAPK1 protein]21871873
C006780bisphenol Abisphenol A inhibits the reaction [NGF protein results in increased phosphorylation of MAPK3 protein]21871873
C006780bisphenol Abisphenol A results in decreased susceptibility to NGF protein21871873
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NGF mRNA22079614
D001971BromocriptineBromocriptine results in increased secretion of NGF protein12770616
D002038BungarotoxinsBungarotoxins results in increased expression of NGF mRNA8478687
D019328Buthionine SulfoximineAcetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of NGF mRNA]23472850
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased expression of NGF mRNA23472850
D019328Buthionine SulfoximineNGF protein affects the reaction [Buthionine Sulfoximine results in increased expression of NFKBIA mRNA]23472850
D019328Buthionine SulfoximineNGF protein affects the reaction [Buthionine Sulfoximine results in increased expression of TXN1 mRNA]23472850
D019328Buthionine SulfoximineNGF protein affects the reaction [Buthionine Sulfoximine results in increased phosphorylation of and results in increased activity of NTRK1 protein]23472850
D019328Buthionine SulfoximineNGF protein affects the susceptibility to Buthionine Sulfoximine23472850
D002084Butylated HydroxytolueneButylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]9748608
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of NGF mRNA15003993
C047047cabergolinecabergoline results in increased expression of NGF mRNA12770616
C047047cabergolinecabergoline results in increased secretion of NGF protein12770616
D002104CadmiumCadmium inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
C028031cadmium acetatecadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of NGF mRNA18974090
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester results in increased expression of NGF protein20836997
D000001Calcimycin[Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in increased expression of NGF protein]24244623
D000001Calcimycin[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased expression of NGF protein24244623
D002118Calciumcadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D002118CalciumCadmium inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D002118Calciumcalmidazolium inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D002118CalciumFluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D002118Calcium"[NGF protein co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] results in increased uptake of Calcium"1374475
D002118Calcium[NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium1374475
D002118CalciumNGF protein results in increased uptake of Calcium1374475
D002118CalciumNifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D002118CalciumOkadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium]1374475
D002118CalciumStaurosporine inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D002118Calcium"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [NGF protein results in increased transport of Calcium]"21981408
D002118Calcium[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [Oxalates inhibits the reaction [NGF protein results in increased transport of Calcium]]21981408
D002118Calcium[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [oxaliplatin inhibits the reaction [NGF protein results in increased transport of Calcium]]21981408
D002118CalciumNGF protein results in increased transport of Calcium21981408
D002118CalciumOxalates inhibits the reaction [NGF protein results in increased transport of Calcium]21981408
D002118Calciumoxaliplatin inhibits the reaction [NGF protein results in increased transport of Calcium]21981408
D002125Calcium Gluconate[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [Oxalates inhibits the reaction [NGF protein results in increased transport of Calcium]]21981408
D002125Calcium Gluconate[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [Oxalates results in decreased susceptibility to NGF protein]21981408
D002125Calcium Gluconate[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [oxaliplatin inhibits the reaction [NGF protein results in increased transport of Calcium]]21981408
D002125Calcium Gluconate[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [oxaliplatin results in decreased susceptibility to NGF protein]21981408
C031938calmidazoliumcalmidazolium inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D002211CapsaicinNTRK1 promotes the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
D002211CapsaicinNTRK1 protein mutant form affects the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
D002211Capsaicinbisindolylmaleimide I inhibits the reaction [NGF results in increased susceptibility to Capsaicin]12815188
D002211CapsaicinCapsaicin inhibits the reaction [CCK protein alternative form results in decreased expression of NGF mRNA]10683199
D002211CapsaicinCapsaicin promotes the reaction [CCK protein alternative form results in increased expression of NGF protein]10683199
D002211CapsaicinCapsaicin results in decreased expression of NGF mRNA10683199
D002211CapsaicinCapsaicin results in increased expression of NGF protein10683199
D002211CapsaicinKN 62 inhibits the reaction [NGF results in increased susceptibility to Capsaicin]12815188
D002211CapsaicinNGF protein results in increased susceptibility to Capsaicin17324588
D002211CapsaicinNGF results in increased susceptibility to Capsaicin12815188
D002211CapsaicinPIK3R1 gene mutant form inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
D002211CapsaicinStaurosporine inhibits the reaction [NGF results in increased susceptibility to Capsaicin]12815188
D002211Capsaicinwortmannin inhibits the reaction [NGF results in increased susceptibility to Capsaicin]12815188
D002211Capsaicin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
D002211Capsaicin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]17324588
D002211Capsaicin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
D002211Capsaicinbisindolylmaleimide I inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
D002211Capsaicin[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein26883566
D002211CapsaicinCapsaicin results in decreased expression of NGF protein9259450
D002211CapsaicinCapsaicin results in increased expression of NGF protein15265675|2215055
D002211Capsaicinepothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]26883566
D002211CapsaicinKetotifen inhibits the reaction [Capsaicin results in increased expression of NGF protein]15265675
D002211Capsaicin[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGF protein]22150557
D002211CapsaicinNaproxen inhibits the reaction [Capsaicin results in increased expression of NGF protein]22150557
D002211CapsaicinNGF protein promotes the reaction [Capsaicin results in increased expression of CALCA protein]16777323
D002211CapsaicinNGF protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]17687396
D002211CapsaicinNGF protein results in increased susceptibility to Capsaicin11166474|1732458
D002211CapsaicinPromethazine inhibits the reaction [Capsaicin results in increased expression of NGF protein]15265675
D002211CapsaicinRanitidine inhibits the reaction [Capsaicin results in increased expression of NGF protein]15265675
D002211Capsaicinspantide II inhibits the reaction [Capsaicin results in increased expression of NGF protein]15265675
D002211Capsaicinstaurosporine aglycone inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]11166474|1732458
D002211CapsaicinSumatriptan inhibits the reaction [Capsaicin results in increased expression of NGF protein]22150557
D002211CapsaicinU 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
D002211CapsaicinU 0126 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]17324588
D002248Carbon MonoxideCarbon Monoxide affects the expression of NGF mRNA27113706
D002248Carbon MonoxideCarbon Monoxide results in decreased expression of and affects the secretion of NGF protein27113706
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of NGF mRNA14578185
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of NGF protein14578185
D002330CarmustineCarmustine affects the activity of NGF protein15935206
D002351CarrageenanCarrageenan results in increased expression of NGF protein10653021
D002351CarrageenanDexamethasone inhibits the reaction [Carrageenan results in increased expression of NGF protein]10653021
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of NGF mRNA15721885
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in decreased expression of SLC7A11 mRNA20600679
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC17A8 mRNA20600679
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC1A1 mRNA20600679
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC1A2 mRNA20600679
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC1A3 mRNA20600679
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC1A4 mRNA20600679
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC1A5 mRNA20600679
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC1A6 mRNA20600679
D004390Chlorpyrifos[Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC1A7 mRNA20600679
D004390ChlorpyrifosChlorpyrifos affects the expression of NGF mRNA17893397
D004390ChlorpyrifosChlorpyrifos affects the expression of NGF protein17893397
D004390ChlorpyrifosChlorpyrifos promotes the reaction [NGF protein results in decreased expression of TUBA3A mRNA]28385489
D004390ChlorpyrifosChlorpyrifos promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]28385489
D004390ChlorpyrifosChlorpyrifos promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]28385489
D004390ChlorpyrifosChlorpyrifos promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]28385489
D004390ChlorpyrifosChlorpyrifos results in decreased expression of NGF mRNA16675515
D002794CholineCholine inhibits the reaction [Sodium Fluoride results in decreased expression of NGF mRNA]27664006
D002794CholineCholine inhibits the reaction [Sodium Fluoride results in decreased expression of NGF protein]27664006
D002794CholineCholine results in increased expression of NGF mRNA27664006
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of NGF mRNA20938992
C043561chrysinchrysin inhibits the reaction [Oxidopamine results in decreased expression of NGF protein]29054324
D007464ClioquinolClioquinol inhibits the reaction [NGF protein results in increased phosphorylation of NTRK1 protein]25758465
D007464Clioquinoltrichostatin A inhibits the reaction [Clioquinol inhibits the reaction [NGF protein results in increased phosphorylation of NTRK1 protein]]25758465
C018021cobaltous chloride[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein24989011
C018021cobaltous chloride[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein24989011
C018021cobaltous chloride[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA24989011
C018021cobaltous chloride[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein24989011
C018021cobaltous chloride[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein24989011
C018021cobaltous chlorideEverolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]24989011
C018021cobaltous chlorideEverolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]24989011
C018021cobaltous chloride[rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA24989011
C018021cobaltous chloriderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]24989011
C018021cobaltous chloriderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]24989011
C018021cobaltous chloriderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]24989011
C018021cobaltous chloriderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein]24989011
C018021cobaltous chloriderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein]24989011
D003042CocaineCocaine results in decreased expression of NGF protein17715210
D005576Colforsin[Colforsin results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA2174743
D005576ColforsinColforsin results in increased expression of NGF mRNA2853697
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of NGF mRNA20971185
D003471CuprizoneCuprizone affects the expression of NGF mRNA27523638
D003474CurcuminCurcumin results in decreased expression of NGF18462866
D003513CycloheximideCycloheximide inhibits the reaction [NGF protein results in increased expression of FOS protein]20495008
D003513CycloheximideCycloheximide inhibits the reaction [NGF protein results in increased expression of SOD2 protein]20495008
D003520Cyclophosphamide"3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]"20127836
D003520CyclophosphamideCyclophosphamide promotes the reaction [NGF results in increased expression of VEGFA mRNA]18632792
D003520CyclophosphamideCyclophosphamide results in increased expression of NGF protein18299998|2012783
D003520CyclophosphamideVIP protein affects the reaction [Cyclophosphamide results in increased expression of NGF protein]18299998
D003520CyclophosphamideCyclophosphamide results in decreased expression of NGF protein10683293
D003520CyclophosphamideCyclophosphamide results in increased expression of NGF mRNA10683293
D003520CyclophosphamideCyclophosphamide results in increased expression of NGF protein16879691
D003520CyclophosphamideNGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]19996110
D003520CyclophosphamideNGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]19996110
D003520CyclophosphamideNGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]19996110
D003520CyclophosphamideNGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]19996110
D003520CyclophosphamideNGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein]19996110
D003520Cyclophosphamiderofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]16879691
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] affects the localization of NFATC1 protein24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] affects the localization of SP1 protein24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] promotes the reaction [SP1 protein binds to CDKN1A promoter]24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in decreased expression of BCL2 mRNA24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in decreased expression of CCND1 mRNA24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in decreased expression of CCND1 protein24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in decreased expression of NTRK1 mRNA24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in increased activity of CASP9 protein24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in increased expression of BAD mRNA24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in increased expression of CDKN1A mRNA24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in increased expression of NGFR mRNA24244623
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in increased expression of TP53 mRNA24244623
D016572CyclosporineCyclosporine results in increased expression of NGF protein24244623
D016572CyclosporineNGFR protein affects the reaction [[Cyclosporine co-treated with NGF protein] results in increased activity of CASP9 protein]24244623
D016572CyclosporinePlicamycin inhibits the reaction [[Cyclosporine co-treated with NGF protein] results in increased expression of CDKN1A mRNA]24244623
D016572Cyclosporine[Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in increased expression of NGF protein]24244623
D016572CyclosporineNGF protein inhibits the reaction [Cyclosporine results in increased activity of CASP3 protein]17385075
C037304cyhalothrincyhalothrin promotes the reaction [NGF protein results in decreased expression of TUBA3A mRNA]28385489
C037304cyhalothrincyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]28385489
C037304cyhalothrincyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]28385489
C037304cyhalothrincyhalothrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]28385489
C037304cyhalothrincyhalothrin promotes the reaction [NGF protein results in increased expression of TUBB3 mRNA]28385489
D003609Dactinomycin"Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA]"22982731
D003609DactinomycinDactinomycin inhibits the reaction [NEPP11 compound results in increased expression of NGF mRNA]22982731
D003609DactinomycinDactinomycin results in decreased expression of NGF mRNA22982731
C017180decamethrindecamethrin inhibits the reaction [NGF protein results in increased expression of CAMK2B mRNA]28385489
C017180decamethrindecamethrin inhibits the reaction [NGF protein results in increased expression of TUBB3 mRNA]28385489
C014347decitabinedecitabine results in increased expression of NGF mRNA27915011
D003671DEET[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NGF mRNA28659758
D013759Dronabinol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dronabinol results in increased expression of NGF protein]12834810
D013759Dronabinol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dronabinol results in increased expression of NGF protein]12834810
D013759DronabinolDronabinol results in increased expression of NGF protein12834810
D003907DexamethasoneDexamethasone results in decreased expression of NGF mRNA19853017
D003907DexamethasoneDexamethasone inhibits the reaction [Carrageenan results in increased expression of NGF protein]10653021
D003907DexamethasoneDexamethasone inhibits the reaction [NGF protein promotes the reaction [Acrylamide results in increased expression of NEFM protein]]10678756
D003907DexamethasoneDexamethasone inhibits the reaction [NGF protein results in increased expression of NEFM protein]10678756
D003907DexamethasoneDexamethasone results in increased expression of NGF mRNA1996081
D003907DexamethasoneDexamethasone results in increased expression of NGF protein1996081
D003976Diazinon[Diazinon co-treated with NGF protein] results in decreased expression of SLC17A8 mRNA20600679
D003976Diazinon[Diazinon co-treated with NGF protein] results in increased expression of SLC1A4 mRNA20600679
D003976Diazinon[Diazinon co-treated with NGF protein] results in increased expression of SLC1A5 mRNA20600679
D003976DiazinonDiazinon results in decreased expression of NGF mRNA23212306
D003976Diazinon[TLR4 protein mutant form results in increased susceptibility to Diazinon] which results in decreased expression of NGF mRNA22428454
D003976DiazinonDiazinon affects the expression of NGF mRNA19130878
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NGF mRNA21266533
D002945CisplatinCisplatin promotes the reaction [jinfukang results in decreased expression of NGF mRNA]27392435
D002945CisplatinCisplatin results in decreased expression of NGF mRNA27392435
D002945Cisplatinjinfukang promotes the reaction [Cisplatin results in decreased expression of NGF mRNA]27392435
D002945CisplatinAcetylcarnitine inhibits the reaction [Cisplatin results in decreased expression of NGF protein]14654561
D002945CisplatinCisplatin results in decreased expression of NGF protein14654561|2186557
D002945CisplatinNGF protein results in decreased susceptibility to Cisplatin10553948|9622663
D002945CisplatinTretinoin inhibits the reaction [Cisplatin results in decreased expression of NGF protein]21865574
D004026Dieldrin[Dieldrin co-treated with NGF protein] results in increased expression of SLC1A5 mRNA20600679
D004026Dieldrin[Dieldrin co-treated with NGF protein] results in increased expression of SLC7A11 mRNA20600679
D004026DieldrinDieldrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]28385489
D004041Dietary FatsDietary Fats results in increased expression of NGF mRNA25016146
C015144dihydrolipoic aciddihydrolipoic acid inhibits the reaction [NGF protein results in increased expression of MAP2 protein]21462292
D002117CalcitriolCalcitriol results in increased expression of NGF mRNA16002434
D002117CalcitriolCalcitriol results in increased expression of NGF19603526
C042986ebselenebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]20495008
C042986ebselenebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]20495008
C060297echinacosideechinacoside inhibits the reaction [Rotenone results in decreased expression of NGF protein]23189969
C060297echinacosidestaurosporine aglycone inhibits the reaction [echinacoside inhibits the reaction [Rotenone results in decreased expression of NGF protein]]23189969
C508214(E)-N1-((6-chloro-3-pyridyl)methyl)-N2-cyano-N1-methylacetamidine(E)-N1-((6-chloro-3-pyridyl)methyl)-N2-cyano-N1-methylacetamidine promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]28385489
C508214(E)-N1-((6-chloro-3-pyridyl)methyl)-N2-cyano-N1-methylacetamidine(E)-N1-((6-chloro-3-pyridyl)methyl)-N2-cyano-N1-methylacetamidine promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]28385489
C038131epalrestatepalrestat inhibits the reaction [Streptozocin results in decreased expression of NGF protein]9628756
C038131epalrestatepalrestat results in increased expression of NGF protein9628756
C038131epalrestatepalrestat results in increased secretion of NGF protein9628756
C053090epinastineepinastine results in decreased expression of NGF protein19937255
C093788epothilone Bepothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]26883566
C093788epothilone Bepothilone B promotes the reaction [[Potassium co-treated with NGF protein] results in increased secretion of CALCA protein]26883566
D004976Ethacrynic AcidEthacrynic Acid results in increased expression of NGF mRNA10407097
D000431EthanolEthanol results in decreased expression of NGF protein19397965
D000431EthanolEthanol results in decreased expression of NGF protein19100286
D000431EthanolEthanol results in increased expression of NGF mRNA23770283
D000431EthanolEthanol results in increased expression of NGF protein23770283
D000431Ethanolresveratrol inhibits the reaction [Ethanol results in increased expression of NGF protein]23770283
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NGF mRNA17942748
D000068338EverolimusEverolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]24989011
D000068338EverolimusEverolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]24989011
D005476FluphenazineFluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
D005485FlutamideFlutamide results in decreased expression of NGF protein25051504
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of NGF mRNA20938992
D005557FormaldehydeFormaldehyde results in decreased expression of NGF protein15003329
D005557FormaldehydeFormaldehyde results in increased expression of NGF mRNA15467352
D005557FormaldehydeFormaldehyde results in increased expression of NGF protein15467352
D005620Freund's AdjuvantFreund's Adjuvant results in increased expression of NGF mRNA16914685
D005632FructoseFructose results in decreased expression of NGF mRNA18585860
D005632FructoseFructose results in decreased expression of NGF protein18585860
C069837fullerene C60fullerene C60 affects the expression of NGF mRNA19167457
C002469fusarenon-Xfusarenon-X results in increased expression of NGF mRNA24983900
D019833Genistein[Genistein co-treated with Methoxychlor] results in decreased expression of NGF mRNA21782745
D019833Genistein[Genistein co-treated with vinclozolin] results in decreased expression of NGF mRNA22317923
D019833Genistein[Genistein co-treated with vinclozolin] results in increased expression of NGF mRNA23410115
D005839GentamicinsGentamicins results in decreased expression of NGF protein15033597|2505150
C049863ginsenoside Rdginsenoside Rd results in increased expression of NGF mRNA24599032
C049864ginsenoside Reginsenoside Re results in increased expression of NGF mRNA24599032
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA]17109745
D005947GlucoseBerberine inhibits the reaction [Glucose results in decreased expression of NGF protein]23954465
D005947GlucoseGlucose results in decreased expression of NGF protein23954465
D005947GlucoseGlucose results in decreased activity of NGF protein19501110
D005978GlutathioneNGF protein affects the oxidation of Glutathione23472850
D005978GlutathioneNGF protein affects the reduction of Glutathione23472850
D005978GlutathioneGlutathione affects the activity of NGF protein12381813
D005978GlutathioneN-acetylsphingosine affects the reaction [Glutathione affects the activity of NGF protein]12381813
D019803Glutathione DisulfideNGF protein affects the abundance of Glutathione Disulfide23472850
C004312glycidolglycidol results in decreased expression of NGF mRNA24915197
C081021Go 6976Go 6976 inhibits the reaction [NGF protein results in increased expression of SERPINE1 mRNA]23825664
C081021Go 6976Go 6976 inhibits the reaction [NGF protein results in increased expression of SERPINE1 protein]23825664
D006533HeptachlorHeptachlor promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]28385489
D006533HeptachlorHeptachlor promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]28385489
D006533HeptachlorHeptachlor promotes the reaction [NGF protein results in increased expression of TUBB3 mRNA]28385489
D003932HeroinHeroin results in decreased expression of NGF protein17715210
D006632Histamine[Histamine binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein15167971
D006632HistaminePyrilamine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein]15167971
D006632HistamineTriprolidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein]15167971
C118994histaprodifen[histaprodifen binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein15167971
D006861Hydrogen PeroxideNGF protein results in decreased susceptibility to Hydrogen Peroxide15935206
D007213IndomethacinIndomethacin results in increased expression of NGF mRNA16984733
D007545Isoproterenol[Isoproterenol results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA2174743
D007545IsoproterenolIsoproterenol results in increased expression of NGF mRNA2174743|2853697
D007545IsoproterenolPropranolol inhibits the reaction [Isoproterenol results in increased expression of NGF mRNA]2174743|2853697
C544151jinfukangCisplatin promotes the reaction [jinfukang results in decreased expression of NGF mRNA]27392435
C544151jinfukangjinfukang promotes the reaction [Cisplatin results in decreased expression of NGF mRNA]27392435
D007649KetamineKetamine inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA]8635431
D007665KetotifenKetotifen inhibits the reaction [Capsaicin results in increased expression of NGF protein]15265675
C063302KN 62KN 62 inhibits the reaction [NGF results in increased susceptibility to Capsaicin]12815188
C008261lead acetatelead acetate affects the expression of NGF mRNA24260418
C008261lead acetate2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead acetate results in increased activity of NGF protein]11233754
C008261lead acetatelead acetate results in increased activity of NGF protein11233754
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of NGF mRNA12057914
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of NGF protein21570423
D008278Magnesium Sulfate[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [Oxalates inhibits the reaction [NGF protein results in increased transport of Calcium]]21981408
D008278Magnesium Sulfate[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [Oxalates results in decreased susceptibility to NGF protein]21981408
D008278Magnesium Sulfate[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [oxaliplatin inhibits the reaction [NGF protein results in increased transport of Calcium]]21981408
D008278Magnesium Sulfate[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [oxaliplatin results in decreased susceptibility to NGF protein]21981408
D008294MalathionMalathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]28385489
D008294MalathionMalathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]28385489
D008345Manganese[Manganese co-treated with NGF protein] results in decreased expression of BCL2L1 protein25791630
D008345Manganese[Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein25791630
D008345Manganese[Manganese co-treated with NGF protein] results in decreased expression of PPM1D protein25791630
D008345Manganese[Manganese co-treated with NGF protein] results in increased cleavage of PARP1 protein25791630
D008345Manganese[Manganese co-treated with NGF protein] results in increased expression of and affects the localization of TP53 protein25448048
D008345Manganese[Manganese co-treated with NGF protein] results in increased expression of BAX protein25791630
D008345Manganese[Manganese co-treated with NGF protein] results in increased phosphorylation of and results in increased expression of TP53 protein25791630
D008345ManganesePPM1D mutant form promotes the reaction [[Manganese co-treated with NGF protein] results in increased cleavage of PARP1 protein]25791630
D008345ManganesePPM1D mutant form promotes the reaction [[Manganese co-treated with NGF protein] results in increased phosphorylation of TP53 protein]25791630
D008345ManganesePPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in decreased cleavage of PARP1 protein]25791630
D008345ManganesePPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in decreased expression of BCL2L1 protein]25791630
D008345ManganesePPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein]25791630
D008345ManganesePPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in increased expression of BAX protein]25791630
D008345ManganesePPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in increased phosphorylation of TP53 protein]25791630
C025340manganese chloridemanganese chloride results in increased methylation of NGF gene27913844
C013592mangiferinmangiferin results in increased secretion of NGF protein20303935
D009637MasoprocolMasoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
D009637MasoprocolMasoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
D008628MercuryMercury results in increased expression of NGF mRNA16823088
D008628MercuryMercury results in decreased expression of NGF mRNA7781173
D008628MercuryMercury results in increased expression of NGF mRNA7781173
D008694MethamphetamineNGF protein results in decreased susceptibility to Methamphetamine15093677
D008694Methamphetamine[Methamphetamine co-treated with NGF protein] affects the abundance of Peroxynitrous Acid12105096
C088155methanandamide2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [methanandamide results in increased expression of NGF protein]12834810
C088155methanandamidemethanandamide results in increased expression of NGF protein12834810
D008701MethapyrileneMethapyrilene results in increased expression of NGF mRNA22484513
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of NGF mRNA20938992
D008727MethotrexateMethotrexate results in increased expression of NGF mRNA17400583
D008731Methoxychlor[Genistein co-treated with Methoxychlor] results in decreased expression of NGF mRNA21782745
D008748Methylcholanthrene[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NGF mRNA23519560
D008748MethylcholanthreneMethylcholanthrene results in increased expression of NGF mRNA20713471
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of NGF mRNA7863520
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of and results in increased secretion of NGF protein7863520
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased susceptibility to NGF protein7863520
D008743Methyl ParathionMethyl Parathion affects the expression of NGF mRNA17893397
D008743Methyl ParathionMethyl Parathion affects the expression of NGF protein17893397
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of NGF mRNA25234470
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased susceptibility to NGF protein21145954
D009151Mustard GasMustard Gas results in decreased expression of NGF mRNA16173061
D009151Mustard GasMustard Gas results in increased expression of NGF mRNA15674843|1895507
C064769N-acetylsphingosineN-acetylsphingosine affects the reaction [Glutathione affects the activity of NGF protein]12381813
C031721naphthalenenaphthalene results in increased expression of NGF mRNA18978301
C031721naphthaleneNGF protein results in decreased susceptibility to naphthalene20075049
D009288Naproxen[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGF protein]22150557
D009288NaproxenNaproxen inhibits the reaction [Capsaicin results in increased expression of NGF protein]22150557
C424427NEPP11 compoundDactinomycin inhibits the reaction [NEPP11 compound results in increased expression of NGF mRNA]22982731
C424427NEPP11 compoundNEPP11 compound results in increased expression of NGF mRNA22982731
D009532Nickel[Nickel co-treated with NGF protein] results in increased expression of SLC1A5 mRNA20600679
D009532NickelNickel affects the expression of NGF mRNA19130878
C028007nickel monoxidenickel monoxide results in decreased expression of NGF mRNA19167457
D009543NifedipineNifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
C012655nimesulidenimesulide inhibits the reaction [NGF protein results in increased secretion of Dinoprostone]21811393
C012655nimesulidenimesulide inhibits the reaction [NGF protein results in increased secretion of TAC1 protein]21811393
C012655nimesulidenimesulide inhibits the reaction [NGF results in increased expression of TAC1 mRNA]21811393
D009569Nitric OxideNitric Oxide affects the reaction [NGF protein results in increased activity of MAPK1 protein]14713289
D009569Nitric OxideNitric Oxide affects the reaction [NGF protein results in increased activity of MAPK3 protein]14713289
C087567N-methyltropan-3-yl 2-(4-bromophenyl)propionateN-methyltropan-3-yl 2-(4-bromophenyl)propionate results in increased expression of NGF protein9869257
D015739NocodazoleNocodazole inhibits the reaction [NGF protein affects the localization of NTRK1 protein]17822405
D015739NocodazoleNocodazole inhibits the reaction [NGF protein affects the localization of RAP1A protein]17822405
D015739NocodazoleNocodazole inhibits the reaction [NGF protein results in increased activity of MAPK1 protein]17822405
D015739NocodazoleNocodazole inhibits the reaction [NGF protein results in increased activity of MAPK3 protein]17822405
D015739NocodazoleNocodazole inhibits the reaction [NGF protein results in increased activity of RAP1A protein]17822405
D009638NorepinephrineNorepinephrine results in decreased expression of NGF mRNA8593794
D009638NorepinephrineNorepinephrine results in decreased expression of NGF protein8593794
D009638NorepinephrineNGF protein inhibits the reaction [Norepinephrine affects the localization of XBP1 protein]16338971
D009638NorepinephrineNGF protein inhibits the reaction [Norepinephrine results in decreased expression of AKT1 protein modified form]16338971
D009638NorepinephrineNGF protein inhibits the reaction [Norepinephrine results in increased cleavage of CASP12 protein alternative form]16338971
D009638NorepinephrineNGF protein inhibits the reaction [Norepinephrine results in increased cleavage of CASP3 protein]16338971
D009638NorepinephrineNGF protein inhibits the reaction [Norepinephrine results in increased expression of DDIT3 protein]16338971
D009638NorepinephrineNGF protein inhibits the reaction [Norepinephrine results in increased expression of HSPA5 protein]16338971
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of NGF mRNA20971185
C558013NSC 689534NSC 689534 results in increased expression of NGF mRNA20971185
D016627Oxidopaminechrysin inhibits the reaction [Oxidopamine results in decreased expression of NGF protein]29054324
D016627OxidopamineOxidopamine results in decreased expression of NGF protein29054324
D019319Okadaic AcidOkadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium]1374475
D010070Oxalates[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [Oxalates inhibits the reaction [NGF protein results in increased transport of Calcium]]21981408
D010070Oxalates[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [Oxalates results in decreased susceptibility to NGF protein]21981408
D010070OxalatesOxalates inhibits the reaction [NGF protein results in increased expression of GAP43 protein]21981408
D010070OxalatesOxalates inhibits the reaction [NGF protein results in increased transport of Calcium]21981408
D010070OxalatesOxalates results in decreased susceptibility to NGF protein21981408
C030110oxaliplatin[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [oxaliplatin inhibits the reaction [NGF protein results in increased transport of Calcium]]21981408
C030110oxaliplatin[Magnesium Sulfate co-treated with Calcium Gluconate] inhibits the reaction [oxaliplatin results in decreased susceptibility to NGF protein]21981408
C030110oxaliplatinoxaliplatin inhibits the reaction [NGF protein results in increased expression of GAP43 protein]21981408
C030110oxaliplatinoxaliplatin inhibits the reaction [NGF protein results in increased transport of Calcium]21981408
C030110oxaliplatinoxaliplatin results in decreased susceptibility to NGF protein21981408
D010100OxygenOxygen affects the expression of NGF mRNA19954754
D010100OxygenNGF protein inhibits the reaction [Quercetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of AKT1 protein]]26476374
D010100OxygenNGF protein inhibits the reaction [Quercetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of NTRK1 protein]]26476374
D010100OxygenOxygen deficiency results in increased expression of NGF mRNA18541227
D010100Oxygenpanaxydol promotes the reaction [Oxygen deficiency results in increased expression of NGF mRNA]18541227
D010126OzoneNGF protein promotes the reaction [Ozone results in increased expression of CXCL1 protein]11463606
D010126OzoneNGF protein promotes the reaction [Ozone results in increased expression of TNF protein]11463606
D010126OzoneOzone results in increased expression of NGF mRNA16716893
D017239PaclitaxelNGF protein results in decreased susceptibility to Paclitaxel10553948|9622663
D017239PaclitaxelPaclitaxel results in decreased expression of NGF protein21865574
D017239PaclitaxelTretinoin inhibits the reaction [Paclitaxel results in decreased expression of NGF protein]21865574
C055778panaxydolpanaxydol promotes the reaction [Oxygen deficiency results in increased expression of NGF mRNA]18541227
C055778panaxydolpanaxydol results in increased expression of and results in increased secretion of NGF protein18805406
C055778panaxydolpanaxydol results in increased secretion of NGF protein18541227
C113399PD 166866PD 166866 inhibits the reaction [FGF1 protein results in increased expression of and results in increased secretion of NGF protein]15773903
C096822PD 90780PD 90780 inhibits the reaction [NGF protein binds to NGFR protein]18842820
C074968pentaacetyl geniposide2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C074968pentaacetyl geniposide2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
C074968pentaacetyl geniposideMasoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C074968pentaacetyl geniposideMasoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
C074968pentaacetyl geniposidepentaacetyl geniposide results in increased expression of NGF mRNA17651887
C074968pentaacetyl geniposidepentaacetyl geniposide results in increased expression of NGF protein17651887
C074968pentaacetyl geniposidepyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C074968pentaacetyl geniposidepyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
C074968pentaacetyl geniposidepyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C074968pentaacetyl geniposidepyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
C074968pentaacetyl geniposideSB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C074968pentaacetyl geniposideSB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of NGF protein25524167
D010479PergolidePergolide results in increased expression of NGF mRNA12770616
D010479PergolidePergolide results in increased secretion of NGF protein12770616
D026023Permethrin[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NGF mRNA28659758
D030421Peroxynitrous Acid[Methamphetamine co-treated with NGF protein] affects the abundance of Peroxynitrous Acid12105096
D015232DinoprostoneAcetaminophen affects the reaction [NGF protein results in increased secretion of Dinoprostone]21811393
D015232DinoprostoneNGF protein results in increased secretion of Dinoprostone21811393
D015232Dinoprostonenimesulide inhibits the reaction [NGF protein results in increased secretion of Dinoprostone]21811393
C005435phenylmethylpyrazolonephenylmethylpyrazolone results in increased expression of NGF mRNA19954754
C005435phenylmethylpyrazolonephenylmethylpyrazolone results in increased expression of NGF protein19954754
C005435phenylmethylpyrazolonepyrazolanthrone inhibits the reaction [phenylmethylpyrazolone results in increased expression of NGF mRNA]19954754
C005435phenylmethylpyrazolonepyrazolanthrone inhibits the reaction [phenylmethylpyrazolone results in increased expression of NGF protein]19954754
C005435phenylmethylpyrazoloneU 0126 inhibits the reaction [phenylmethylpyrazolone results in increased expression of NGF mRNA]19954754
C005435phenylmethylpyrazoloneU 0126 inhibits the reaction [phenylmethylpyrazolone results in increased expression of NGF protein]19954754
D010743PhospholipidsNGF protein results in increased methylation of Phospholipids6315882
D010862PilocarpineKetamine inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA]8635431
D010862PilocarpinePilocarpine results in increased expression of NGF mRNA15183516|1797186
D010862PilocarpineScopolamine Hydrobromide inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA]8635431
D010862PilocarpinePilocarpine results in increased expression of NGF protein18815271
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of NGF mRNA19710929
C006253pirinixic acidpirinixic acid results in decreased expression of NGF mRNA20813756
D008926PlicamycinPlicamycin inhibits the reaction [[Cyclosporine co-treated with NGF protein] results in increased expression of CDKN1A mRNA]24244623
D011188Potassiumepothilone B promotes the reaction [[Potassium co-treated with NGF protein] results in increased secretion of CALCA protein]26883566
D011188Potassium[Potassium co-treated with NGF protein] results in increased secretion of CALCA protein26883566
C035988procymidoneprocymidone results in decreased expression of NGF mRNA15686871
D011374ProgesteroneProgesterone results in increased expression of NGF protein16436532
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of NGF mRNA21277368
D011374ProgesteroneProgesterone inhibits the reaction [Estradiol results in increased expression of NGF protein]15570173
D011374Progesterone[VIP protein results in increased secretion of Progesterone] which results in decreased expression of NGF mRNA20150881
D011398PromethazinePromethazine inhibits the reaction [Capsaicin results in increased expression of NGF protein]15265675
D015742PropofolBicuculline inhibits the reaction [Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]11991087
D015742PropofolPropofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]11991087
D011433PropranololPropranolol inhibits the reaction [Isoproterenol results in increased expression of NGF mRNA]2174743|2853697
C043680ptaquiloside[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of NGF mRNA23274088
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [phenylmethylpyrazolone results in increased expression of NGF mRNA]19954754
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [phenylmethylpyrazolone results in increased expression of NGF protein]19954754
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
D0014983-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester"[NGF protein co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] results in increased uptake of Calcium"1374475
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NGF mRNA28659758
D011738PyrilaminePyrilamine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein]15167971
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
D011794QuercetinNGF protein inhibits the reaction [Quercetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of AKT1 protein]]26476374
D011794QuercetinNGF protein inhibits the reaction [Quercetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of NTRK1 protein]]26476374
D011899RanitidineRanitidine inhibits the reaction [Capsaicin results in increased expression of NGF protein]15265675
D017382Reactive Oxygen SpeciesNGF protein results in decreased abundance of Reactive Oxygen Species20495008
D017382Reactive Oxygen SpeciesNGF protein affects the abundance of Reactive Oxygen Species9349553
D012110ReserpineReserpine results in increased expression of NGF mRNA1996081|8593794
D012110ReserpineReserpine results in increased expression of NGF protein1996081|8593794
C059514resveratrolresveratrol inhibits the reaction [Ethanol results in increased expression of NGF protein]23770283
C009172rhodiolosideEverolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]24989011
C009172rhodiolosideEverolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]24989011
C009172rhodioloside[rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA24989011
C009172rhodiolosiderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]24989011
C009172rhodiolosiderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]24989011
C009172rhodiolosiderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]24989011
C009172rhodiolosiderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein]24989011
C009172rhodiolosiderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein]24989011
C116926rofecoxibrofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]16879691
D012402Rotenoneechinacoside inhibits the reaction [Rotenone results in decreased expression of NGF protein]23189969
D012402RotenoneRotenone results in decreased expression of NGF protein23189969
D012402Rotenonestaurosporine aglycone inhibits the reaction [echinacoside inhibits the reaction [Rotenone results in decreased expression of NGF protein]]23189969
C085746rottlerinrottlerin inhibits the reaction [NGF results in increased phosphorylation of TRPV1 protein]16319926
C093642SB 203580SB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]17651887
C093642SB 203580SB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]17651887
C093642SB 203580SB 203580 results in decreased activity of NGF protein9733710
D012601Scopolamine HydrobromideNGF protein results in increased susceptibility to Scopolamine Hydrobromide1661212
D012601Scopolamine HydrobromideNGF protein results in decreased susceptibility to Scopolamine Hydrobromide16405025
D012601Scopolamine HydrobromideScopolamine Hydrobromide inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA]8635431
C027744S-methylisothiopseudouroniumS-methylisothiopseudouronium inhibits the reaction [NGF protein results in increased activity of CHAT protein]12065671
C027744S-methylisothiopseudouroniumS-methylisothiopseudouronium inhibits the reaction [NGF protein results in increased expression of CHAT mRNA]12065671
C017947sodium arsenitesodium arsenite results in increased expression of NGF mRNA16014739|2347285
D012969Sodium FluorideCholine inhibits the reaction [Sodium Fluoride results in decreased expression of NGF mRNA]27664006
D012969Sodium FluorideCholine inhibits the reaction [Sodium Fluoride results in decreased expression of NGF protein]27664006
D012969Sodium FluorideSodium Fluoride results in decreased expression of NGF mRNA27664006
D012969Sodium FluorideSodium Fluoride results in decreased expression of NGF protein27664006
D018038Sodium Selenite[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of NGF mRNA23274088
D018038Sodium SeleniteSodium Selenite results in decreased expression of NGF mRNA23274088
C026411sorbinilsorbinil inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]9748608
C065446spantide IIspantide II inhibits the reaction [Capsaicin results in increased expression of NGF protein]15265675
D019311StaurosporineStaurosporine inhibits the reaction [NGF results in increased susceptibility to Capsaicin]12815188
D019311StaurosporineStaurosporine inhibits the reaction [NGF protein results in increased uptake of Calcium]1374475
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [echinacoside inhibits the reaction [Rotenone results in decreased expression of NGF protein]]23189969
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [NGF protein results in increased expression of GAP43 protein]27871898
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [NGF protein results in increased expression of SYN1 protein]27871898
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [NGF protein results in increased expression of SYP protein]27871898
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [NGF protein results in increased phosphorylation of AKT1 protein]17324588
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]11166474|1732458
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [NTRK1 protein results in increased expression of NGF mRNA]20658530
D013311Streptozocin4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein]8195800
D013311StreptozocinButylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]9748608
D013311Streptozocinepalrestat inhibits the reaction [Streptozocin results in decreased expression of NGF protein]9628756
D013311Streptozocinsorbinil inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]9748608
D013311StreptozocinStreptozocin affects the localization of NGF protein12031555
D013311StreptozocinStreptozocin results in decreased expression of NGF protein8195800|9628756
D013311StreptozocinStreptozocin results in increased expression of NGF mRNA9748608
D018170Sumatriptan[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGF protein]22150557
D018170SumatriptanSumatriptan inhibits the reaction [Capsaicin results in increased expression of NGF protein]22150557
D018170SumatriptanSumatriptan inhibits the reaction [NGF protein results in increased expression of CALCA mRNA]12574409
D014284TriiodothyronineTriiodothyronine results in decreased expression of NGF mRNA17399805
D016559TacrolimusNGF protein inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]17385075
D016559TacrolimusTacrolimus inhibits the reaction [NGF protein results in increased expression of SERPINE1 mRNA]23825664
D016559TacrolimusTacrolimus inhibits the reaction [NGF protein results in increased expression of SERPINE1 protein]23825664
D013726TerbutalineTerbutaline results in decreased expression of NGF mRNA11325809
D013726TerbutalineTerbutaline results in decreased expression of NGF protein11325809
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of NGF mRNA25172293
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NGF mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the reaction [NGF protein results in increased activity of ACHE protein]27502150
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in increased expression of NGF protein]24244623
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased expression of NGF protein24244623
D013755Tetradecanoylphorbol Acetate[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NGF mRNA23519560
D0156472,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine"2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of NGF mRNA"12770616
D0156472,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine"2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased secretion of NGF protein"12770616
D019284ThapsigarginNGF protein inhibits the reaction [Thapsigargin results in decreased expression of AKT1 protein modified form]16338971
D019284ThapsigarginNGF protein inhibits the reaction [Thapsigargin results in increased cleavage of CASP12 protein alternative form]16338971
D019284ThapsigarginNGF protein inhibits the reaction [Thapsigargin results in increased cleavage of CASP3 protein]16338971
D013849ThimerosalNGF protein results in decreased susceptibility to Thimerosal15843506
D013849Thimerosal[Thimerosal co-treated with NGF protein] results in decreased phosphorylation of NTRK1 protein15843506
D013874ThiopentalBicuculline inhibits the reaction [Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]11991087
D013874ThiopentalThiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]11991087
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of NGF protein19750110
D014050TolueneToluene results in increased expression of NGF mRNA19932712
D014050TolueneToluene results in increased expression of NGF protein17481687|1993271
D014051Toluene 2,4-Diisocyanate"NGF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of TAC1 protein]"14672914
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of NGF protein"14672914|1602019
D014118Toxins, Biological"Toxins, Biological affects the expression of NGF mRNA"19682533
D014212TretinoinTretinoin inhibits the reaction [Cisplatin results in decreased expression of NGF protein]21865574
D014212TretinoinTretinoin inhibits the reaction [Paclitaxel results in decreased expression of NGF protein]21865574
D014212TretinoinTretinoin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]28385489
D014241TrichloroethyleneTrichloroethylene results in decreased expression of NGF mRNA22421312
C012589trichostatin Atrichostatin A inhibits the reaction [Clioquinol inhibits the reaction [NGF protein results in increased phosphorylation of NTRK1 protein]]25758465
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of NGF mRNA17385238
D010853Picryl ChloridePicryl Chloride results in increased expression of NGF mRNA21804303
D014311TriprolidineTriprolidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein]15167971
C001899triptolidetriptolide results in increased expression of NGF mRNA17401680
C001899triptolidetriptolide results in increased expression of NGF protein17401680
C001899triptolidetriptolide results in increased secretion of NGF protein17401680
C113580U 0126U 0126 inhibits the reaction [phenylmethylpyrazolone results in increased expression of NGF mRNA]19954754
C113580U 0126U 0126 inhibits the reaction [phenylmethylpyrazolone results in increased expression of NGF protein]19954754
C113580U 0126U 0126 inhibits the reaction [NGF protein results in increased expression of and results in increased phosphorylation of SOD2 protein]20495008
C113580U 01262-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]17324588
C113580U 0126U 0126 inhibits the reaction [NGF protein results in increased expression of CALCA mRNA]12574409
C113580U 0126U 0126 inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]14713289
C113580U 0126U 0126 inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]14713289
C113580U 0126U 0126 inhibits the reaction [NGF protein results in increased phosphorylation of MAPK1 protein]17324588
C113580U 0126U 0126 inhibits the reaction [NGF protein results in increased phosphorylation of MAPK3 protein]17324588
C113580U 0126U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]17324588
C113580U 0126U 0126 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]17324588
C113580U 0126U 0126 promotes the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAP2K1 protein]14713289
C113580U 0126U 0126 promotes the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAP2K2 protein]14713289
C419664udenafiludenafil results in decreased expression of NGF21366883
D014635Valproic AcidValproic Acid results in increased expression of NGF mRNA10689198
D001335Vehicle EmissionsVehicle Emissions affects the methylation of NGF gene25560391
D001335Vehicle EmissionsVehicle Emissions results in increased expression of NGF mRNA23358141
D014747VinblastineVinblastine results in decreased susceptibility to NGF protein9524088
C025643vinclozolin[Genistein co-treated with vinclozolin] results in decreased expression of NGF mRNA22317923
C025643vinclozolin[Genistein co-treated with vinclozolin] results in increased expression of NGF mRNA23410115
C025643vinclozolinvinclozolin results in decreased expression of NGF mRNA15686871
D014750VincristineBicuculline inhibits the reaction [Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]11991087
D014750VincristineBicuculline inhibits the reaction [Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]11991087
D014750VincristineNGF protein results in decreased susceptibility to Vincristine10553948|9622663
D014750VincristinePropofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]11991087
D014750VincristineThiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]11991087
D014750VincristineVincristine results in decreased susceptibility to NGF protein11991087|9524088
D014751VindesineVindesine results in decreased susceptibility to NGF protein9524088
C121611VIVIT peptideVIVIT peptide inhibits the reaction [NGF protein results in increased expression of SERPINE1 protein]23825664
C009687wortmanninwortmannin inhibits the reaction [NGF results in increased localization of TRPV1 protein]16319926
C009687wortmanninwortmannin inhibits the reaction [NGF results in increased susceptibility to Capsaicin]12815188
C009687wortmanninwortmannin inhibits the reaction [NGF protein promotes the reaction [YWHAB protein binds to CDC5L protein]]20629186
C009687wortmanninwortmannin inhibits the reaction [NGF protein promotes the reaction [YWHAB protein binds to PRPF19 protein modified form]]20629186
C009687wortmanninwortmannin inhibits the reaction [NGF protein results in increased phosphorylation of AKT1 protein]17324588
C009687wortmanninwortmannin results in decreased activity of NGF protein21975456

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005163nerve growth factor receptor binding-IBA21873635  
GO:0005163nerve growth factor receptor binding-IPI14985763  
GO:0005515protein binding-IPI10490030  14985763  15131306  15710408  18596692  19122660  
GO:0008083growth factor activity-IBA21873635  
GO:0008191metalloendopeptidase inhibitor activity-IDA20164177  
GO ID GO Term Qualifier Evidence PubMed
GO:0000186activation of MAPKK activity-TAS-  
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process-TAS-  
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway-IBA21873635  
GO:0007267cell-cell signaling-IBA21873635  
GO:0007422peripheral nervous system development-IBA21873635  
GO:0007613memory-IBA21873635  
GO:0008285negative regulation of cell proliferation-TAS10362258  
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors-IDA14985763  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0010628positive regulation of gene expression-IMP16153003  
GO:0010628positive regulation of gene expression-ISS10362258  
GO:0021675nerve development-IBA21873635  
GO:0032455nerve growth factor processing-TAS-  
GO:0038180nerve growth factor signaling pathway-IBA21873635  
GO:0040011locomotion-IBA21873635  
GO:0043065positive regulation of apoptotic process-TAS-  
GO:0043066negative regulation of apoptotic process-TAS-  
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-TAS-  
GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process-TAS-  
GO:0043388positive regulation of DNA binding-ISS10362258  
GO:0043524negative regulation of neuron apoptotic process-IBA21873635  
GO:0045664regulation of neuron differentiation-IBA21873635  
GO:0045666positive regulation of neuron differentiation-TAS10362258  
GO:0046579positive regulation of Ras protein signal transduction-ISS-  
GO:0048011neurotrophin TRK receptor signaling pathway-TAS-  
GO:0048015phosphatidylinositol-mediated signaling-TAS-  
GO:0048672positive regulation of collateral sprouting-IBA21873635  
GO:0048812neuron projection morphogenesis-IBA21873635  
GO:0048812neuron projection morphogenesis-IDA17724343  
GO:0050772positive regulation of axonogenesis-TAS-  
GO:0050804modulation of chemical synaptic transmission-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IBA21873635  
GO:0005768endosome-TAS-  
GO:0005796Golgi lumen-TAS-  
GO:0008021synaptic vesicle-IBA21873635  
GO:0030424axon-IBA21873635  
GO:0030425dendrite-IBA21873635  
GO:0031410cytoplasmic vesicle-IBA21873635  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04210Apoptosis
hsa04722Neurotrophin signaling pathway
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-166520Signaling by NTRKsTAS
R-HSA-166520Signaling by NTRKsIEA
R-HSA-167021PLC-gamma1 signallingIEA
R-HSA-167044Signalling to RASIEA
R-HSA-167060NGF processingTAS
R-HSA-167060NGF processingIEA
R-HSA-169893Prolonged ERK activation eventsTAS
R-HSA-169893Prolonged ERK activation eventsIEA
R-HSA-170968Frs2-mediated activationTAS
R-HSA-170968Frs2-mediated activationIEA
R-HSA-170984ARMS-mediated activationTAS
R-HSA-170984ARMS-mediated activationIEA
R-HSA-177504Retrograde neurotrophin signallingIEA
R-HSA-177504Retrograde neurotrophin signallingTAS
R-HSA-187015Activation of TRKA receptorsIEA
R-HSA-187015Activation of TRKA receptorsTAS
R-HSA-187037Signaling by NTRK1 (TRKA)TAS
R-HSA-187037Signaling by NTRK1 (TRKA)IEA
R-HSA-187042TRKA activation by NGFIEA
R-HSA-187042TRKA activation by NGFTAS
R-HSA-187687Signalling to ERKsTAS
R-HSA-187687Signalling to ERKsIEA
R-HSA-187706Signalling to p38 via RIT and RINIEA
R-HSA-193639p75NTR signals via NF-kBTAS
R-HSA-193639p75NTR signals via NF-kBIEA
R-HSA-193648NRAGE signals death through JNKIEA
R-HSA-193670p75NTR negatively regulates cell cycle via SC1IEA
R-HSA-193681Ceramide signallingIEA
R-HSA-193697p75NTR regulates axonogenesisTAS
R-HSA-193704p75 NTR receptor-mediated signallingTAS
R-HSA-193704p75 NTR receptor-mediated signallingIEA
R-HSA-198203PI3K/AKT activationTAS
R-HSA-198203PI3K/AKT activationIEA
R-HSA-198745Signalling to STAT3IEA
R-HSA-204998Cell death signalling via NRAGE, NRIF and NADETAS
R-HSA-204998Cell death signalling via NRAGE, NRIF and NADEIEA
R-HSA-205017NFG and proNGF binds to p75NTRTAS
R-HSA-205025NADE modulates death signallingTAS
R-HSA-205043NRIF signals cell death from the nucleusTAS
R-HSA-205043NRIF signals cell death from the nucleusIEA
R-HSA-209543p75NTR recruits signalling complexesTAS
R-HSA-209543p75NTR recruits signalling complexesIEA
R-HSA-209560NF-kB is activated and signals survivalTAS
R-HSA-209563Axonal growth stimulationTAS
R-HSA-73887Death Receptor SignallingTAS
R-HSA-73887Death Receptor SignallingIEA
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesIEA
R-HSA-9036866Expression and Processing of NeurotrophinsTAS
R-HSA-9036866Expression and Processing of NeurotrophinsIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23128606Serum brain-derived neurotrophic factor and nerve growth factor concentrations change after alcohol withdrawal: preliminary data of a case-control comparison. (2013)Kohler SEur Addict Res
25296021Nicotine stimulates nerve growth factor in lung fibroblasts through an NFkappaB-dependent mechanism. (2014)Wongtrakool CPLoS One
29183725Involuntary swimming exercise in pregnant rats disturbs ERK1/2 signaling in embryonic neurons through increased cortisol in the amniotic fluid. (2018 Jan 1)Jang YBiochem Biophys Res Commun
15222398Passive smoking elevates neurotrophin levels in tears. (2004 May)Kimata HHum Exp Toxicol
18639986NGF plasma levels increase due to alcohol intoxication and decrease during withdrawal. (2008 Aug)Heberlein APsychoneuroendocrinology
22517242Association of nerve growth factor and vascular endothelial growth factor A with psychometric measurements of opiate dependence: results of a pilot study in patients participating in a structured diamorphine maintenance program. (2012)Heberlein AEur Addict Res
28430931Joint Effects of the Epigenetic Alteration of Neurotrophins and Cytokine Signaling: A Possible Exploratory Model of Affective Symptoms in Alcohol-Dependent Patients? (2017 May 1)Heberlein AAlcohol Alcohol
24893293Chronic alcohol consumption leads to neurochemical changes in the nucleus accumbens that are not fully reversed by withdrawal. (2014 Jul-Aug)Pereira PANeurotoxicol Teratol
14973246A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. (2004 Feb 18)Lu LJ Neurosci
27062604Urinary neurotrophic peptides in postmenopausal women with and without overactive bladder. (2017 Mar)Pennycuff JFNeurourol Urodyn
24331739Neurotrophic factors in women with crack cocaine dependence during early abstinence: the role of early life stress. (2014 May)Viola TWJ Psychiatry Neurosci
16737466Possible role of nerve growth factor in the pathogenesis of alcohol dependence. (2006 Jun)Yoon SJAlcohol Clin Exp Res
12574402Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving. (2003 Feb 1)Grimm JWJ Neurosci
17715210Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor. (2007 Nov)Angelucci FJ Psychopharmacol
26792039Serum Levels of Growth Factors in Alcohol-dependent Patients according to Comorbid Depressive Symptoms. (2016 Feb 29)Han CClin Psychopharmacol Neurosci
21671256Purkinje cell protein 4 positively regulates neurite outgrowth and neurotransmitter release. (2011 Oct)Harashima SJ Neurosci Res
19560628Relation between plasma brain-derived neurotrophic factor and nerve growth factor in the male patients with alcohol dependence. (2009 Jun)Lee BCAlcohol
27071409Associations of Insulin and IGFBP-3 with Lung Cancer Susceptibility in Current Smokers. (2016 Jul)Ho GYFJ Natl Cancer Inst
25747962Prenatal nicotinic exposure augments cardiorespiratory responses to activation of bronchopulmonary C-fibers. (2015 May 1)Zhuang JAm J Physiol Lung Cell Mol Physiol
26346883Expression of BDNF and TrkB Phosphorylation in the Rat Frontal Cortex During Morphine Withdrawal are NO Dependent. (2016 Aug)Peregud DICell Mol Neurobiol
20472139Role of neurotrophic factors in behavioral processes: implications for the treatment of psychiatric and neurodegenerative disorders. (2010)Pardon MCVitam Horm
16179556Cocaine induces a differential dose-dependent alteration in the expression profile of immediate early genes, transcription factors, and caspases in PC12 cells: a possible mechanism of neurotoxic damage in cocaine addiction. (2005 Aug)Imam SZAnn N Y Acad Sci
25419139Decreased serum level of NGF in alcohol-dependent patients with declined executive function. (2014)Bae HNeuropsychiatr Dis Treat
29224006Epigenetic Regulation of the Promotor Region of Vascular Endothelial Growth Factor-A and Nerve Growth Factor in Opioid-Maintained Patients. (2017)Groh AEur Addict Res