Gene: NOTCH2

4853
AGS2|HJCYS|hN2
notch 2
protein-coding
1p12
Ensembl:ENSG00000134250 MIM:600275 Vega:OTTHUMG00000012177 UniprotKB:Q04721
NG_008163.1
PubMed
0   ANCO-SNPs
ND|AD
9   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.876e-1 (AD)  1.599e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ARHGEF260.928
ZNRF30.919
GLI30.914
SLC7A110.909
SLC2A100.909
BMPR1B0.904
ATP13A40.902
ELOVL20.896
TRPS10.895
MSI20.893

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CACNA1F-0.449
QRFPR-0.448
MYOZ3-0.432
DUSP27-0.432
TRABD2A-0.431
GALNT14-0.43
AGMAT-0.43
TMEFF2-0.426
MYCNOS-0.426
CRHBP-0.426

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of NOTCH2 mRNA"23829299
D000082AcetaminophenAcetaminophen results in decreased expression of NOTCH2 mRNA21420995
D000082Acetaminophen[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH2 mRNA25607892
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of NOTCH2 gene27153756
D000393Air PollutantsAir Pollutants analog results in decreased expression of NOTCH2 mRNA21757418
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of NOTCH2 promoter]29094188
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of NOTCH2 mRNA]29094188
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of NOTCH2 promoter]29094188
C011512alpha-naphthoflavonealpha-naphthoflavone results in decreased acetylation of NOTCH2 promoter29094188
C011512alpha-naphthoflavonealpha-naphthoflavone results in increased methylation of NOTCH2 promoter29094188
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NOTCH2 mRNA16483693
D000726Androgen Antagonists[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH2 mRNA25607892
D001151ArsenicNOTCH2 gene SNP affects the susceptibility to Arsenic23967108
C015001arsenitearsenite affects the expression of NOTCH2 mRNA22959463
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of NOTCH2 mRNA"17331233
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NOTCH2 mRNA19181443
D004958EstradiolEstradiol affects the expression of NOTCH2 mRNA23557687
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of NOTCH2 mRNA28628672
C006780bisphenol Abisphenol A promotes the reaction [NOTCH2 protein binds to ESR1 protein]27156127
C006780bisphenol A[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NOTCH2 promoter23359474
C006780bisphenol A[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH2 mRNA25607892
C006780bisphenol A[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NOTCH2 mRNA25607892
C006780bisphenol Abisphenol A results in decreased expression of NOTCH2 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of NOTCH2 gene28505145
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of NOTCH2 mRNA28628672
D000069286BortezomibBortezomib results in decreased expression of NOTCH2 mRNA20977926
D002065BuspironeBuspirone results in decreased expression of NOTCH2 mRNA24136188
C038091butylparaben[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH2 mRNA25607892
C038091butylparaben[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NOTCH2 mRNA25607892
C055494caffeic acid phenethyl ester[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NOTCH2 mRNA20360939
D002220CarbamazepineCarbamazepine affects the expression of NOTCH2 mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of NOTCH2 protein12500195
D002251Carbon TetrachlorideFOXF1 protein affects the reaction [Carbon Tetrachloride results in increased expression of NOTCH2 protein]12500195
D002922CiguatoxinsCiguatoxins affects the expression of NOTCH2 mRNA18353800
D002994ClofibrateClofibrate results in decreased expression of NOTCH2 mRNA22300585
D003471CuprizoneCuprizone results in increased expression of NOTCH2 mRNA26577399
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of NOTCH2 mRNA]27941970
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of NOTCH2 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of NOTCH2 mRNA28628672
C016366dibenzothiophenedibenzothiophene results in increased expression of NOTCH2 mRNA23656968
D003993Dibutyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NOTCH2 promoter23359474
D003993Dibutyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA25607892
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of NOTCH2 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NOTCH2 mRNA15829613
D002945CisplatinCisplatin promotes the reaction [jinfukang results in decreased expression of NOTCH2 mRNA]27392435
D002945Cisplatinjinfukang promotes the reaction [Cisplatin results in decreased expression of NOTCH2 mRNA]27392435
D002945CisplatinNOTCH2 protein affects the susceptibility to Cisplatin16217747
D003633Dichlorodiphenyl Dichloroethylene[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA25607892
C000944dicrotophosdicrotophos results in increased expression of NOTCH2 mRNA28302478
D004026DieldrinDieldrin affects the expression of NOTCH2 mRNA22546817
D004051Diethylhexyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NOTCH2 promoter23359474
D004051Diethylhexyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA25607892
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NOTCH2 mRNA20360939
C118739entinostatentinostat results in increased expression of NOTCH2 mRNA27188386
C038939enzacamene[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH2 mRNA25607892
C038939enzacamene[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NOTCH2 mRNA25607892
C109476epoxiconazole[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA25607892
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of NOTCH2 mRNA17606305
C069837fullerene C60fullerene C60 results in decreased expression of NOTCH2 mRNA19167457
D019833GenisteinGenistein results in decreased expression of NOTCH2 mRNA17341692
D005839GentamicinsGentamicins results in increased expression of NOTCH2 mRNA22061828
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of NOTCH2 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of NOTCH2 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of NOTCH2 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of NOTCH2 mRNA28628672
C544151jinfukangCisplatin promotes the reaction [jinfukang results in decreased expression of NOTCH2 mRNA]27392435
C544151jinfukangjinfukang promotes the reaction [Cisplatin results in decreased expression of NOTCH2 mRNA]27392435
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of NOTCH2 mRNA15618438
D007854Lead[HDAC1 protein co-treated with HDAC2 protein] inhibits the reaction [Lead results in decreased expression of NOTCH2 protein]29301062
D007854LeadLead results in decreased expression of NOTCH2 mRNA29301062
D007854LeadLead results in decreased expression of NOTCH2 protein29301062
D007854Leadtrichostatin A inhibits the reaction [Lead results in decreased expression of NOTCH2 mRNA]29301062
C008261lead acetatelead acetate results in increased expression of NOTCH2 mRNA20542052
C045463leflunomideleflunomide results in increased expression of NOTCH2 mRNA24136188
D008044Linuron[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA25607892
D008044LinuronLinuron results in decreased expression of NOTCH2 mRNA12730624
D008748Methylcholanthrenealpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of NOTCH2 promoter]29094188
D008748Methylcholanthrenealpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of NOTCH2 mRNA]29094188
D008748Methylcholanthrenealpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of NOTCH2 promoter]29094188
D008748MethylcholanthreneMethylcholanthrene results in decreased acetylation of NOTCH2 promoter29094188
D008748MethylcholanthreneMethylcholanthrene results in increased expression of NOTCH2 mRNA29094188
D008748MethylcholanthreneMethylcholanthrene results in increased methylation of NOTCH2 promoter29094188
C091888monoisoamyl-2,3-dimercaptosuccinate"monoisoamyl-2,3-dimercaptosuccinate results in increased expression of NOTCH2 mRNA"19615344
C091888monoisoamyl-2,3-dimercaptosuccinate"[sodium arsenite co-treated with monoisoamyl-2,3-dimercaptosuccinate] results in decreased expression of NOTCH2 mRNA"19615344
C523799MRK 003NOTCH2 inhibits the reaction [MRK 003 results in increased expression of GLI1 mRNA]21169257
D009151Mustard GasIL10 protein affects the reaction [Mustard Gas affects the expression of NOTCH2 mRNA]16173061
D009151Mustard GasMustard Gas results in decreased expression of NOTCH2 mRNA15674843
C000621033napabucasinnapabucasin results in decreased expression of NOTCH2 mRNA25605917
C051752nefazodonenefazodone results in decreased expression of NOTCH2 mRNA24136188
C028007nickel monoxidenickel monoxide results in decreased expression of NOTCH2 mRNA19167457
C012655nimesulidenimesulide results in decreased expression of NOTCH2 mRNA24136188
C419410N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester"N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in decreased cleavage of and results in decreased activity of NOTCH2 protein"22039516
C118580octylmethoxycinnamate[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH2 mRNA25607892
C118580octylmethoxycinnamate[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NOTCH2 mRNA25607892
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of NOTCH2 mRNA25729387
D010098OxycodoneOxycodone results in decreased expression of NOTCH2 mRNA23439660
D010426Pentosan Sulfuric PolyesterPentosan Sulfuric Polyester results in decreased expression of NOTCH2 mRNA28973697
C058305phenethyl isothiocyanateNOTCH2 protein results in increased susceptibility to phenethyl isothiocyanate22039516
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased cleavage of and results in increased activity of and results in increased localization of NOTCH2 protein22039516
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased expression of NOTCH2 mRNA22039516
C006253pirinixic acidpirinixic acid results in decreased expression of NOTCH2 mRNA17426115|1844570
C045362prochloraz[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA25607892
C035988procymidone[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA25607892
D011374ProgesteroneProgesterone results in decreased expression of NOTCH2 mRNA23012394
D011374ProgesteroneProgesterone results in decreased expression of NOTCH2 mRNA18070364
C513428pyrachlostrobinpyrachlostrobin results in increased expression of NOTCH2 mRNA27029645
C059514resveratrolresveratrol results in decreased expression of NOTCH2 mRNA25061499|2589642
C059514resveratrolresveratrol results in decreased expression of NOTCH2 protein25061499|2589642
C059514resveratrolresveratrol results in increased expression of NOTCH2 mRNA21184191
C009166retinol acetateretinol acetate results in increased expression of NOTCH2 mRNA16772331
D012524SarinSarin results in decreased expression of NOTCH2 mRNA19522546
C017947sodium arsenitesodium arsenite affects the expression of NOTCH2 mRNA19590694
C017947sodium arsenitesodium arsenite affects the expression of NOTCH223052196
C017947sodium arsenite"[sodium arsenite co-treated with monoisoamyl-2,3-dimercaptosuccinate] results in decreased expression of NOTCH2 mRNA"19615344
C017947sodium arsenitesodium arsenite results in decreased expression of NOTCH2 mRNA19615344
C017947sodium arsenite[OGG1 gene mutant form results in increased susceptibility to sodium arsenite] which affects the expression of NOTCH2 protein26438402
C017947sodium arsenitesodium arsenite results in increased expression of NOTCH2 protein26438402
D013739TestosteroneTestosterone results in decreased expression of NOTCH2 mRNA19693291
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of NOTCH2 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of NOTCH2 mRNA18796159|2121527
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of NOTCH2 mRNA27404394
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of NOTCH2 mRNA25729387
D019772TopotecanTopotecan results in decreased expression of NOTCH2 mRNA25729387
D014212TretinoinTretinoin results in increased expression of NOTCH2 mRNA22906706|2372400
D014241TrichloroethyleneTrichloroethylene results in increased methylation of NOTCH2 gene27618143
C012589trichostatin Atrichostatin A inhibits the reaction [Lead results in decreased expression of NOTCH2 mRNA]29301062
C080163trovafloxacintrovafloxacin results in decreased expression of NOTCH2 mRNA24136188
D014501UraniumUranium affects the expression of NOTCH2 mRNA15672453
C005460uranyl acetateuranyl acetate affects the expression of NOTCH2 mRNA15672453
D014635Valproic AcidValproic Acid results in decreased methylation of NOTCH2 gene29154799
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of NOTCH2 gene25560391
C025643vinclozolin[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA25607892

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005509calcium ion binding-IEA-  
GO:0005515protein binding-IPI10079256  11101851  11823422  25985737  29149593  
GO:0038023signaling receptor activity-NAS9244302  
GO ID GO Term Qualifier Evidence PubMed
GO:0001709cell fate determination-TAS9244302  
GO:0002315marginal zone B cell differentiation-ISS-  
GO:0003184pulmonary valve morphogenesis-IMP16773578  
GO:0006355regulation of transcription, DNA-templated-TAS9244302  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0006915apoptotic process-TAS12531696  
GO:0007050cell cycle arrest-IDA11306509  
GO:0007219Notch signaling pathway-IDA11306509  25985737  
GO:0007219Notch signaling pathway-TAS-  
GO:0007275multicellular organism development-NAS9244302  
GO:0007399nervous system development-NAS12760378  
GO:0009887animal organ morphogenesis-IEP12531696  
GO:0010629negative regulation of gene expression-IDA11306509  
GO:0019827stem cell population maintenance-TAS11306509  
GO:0030097hemopoiesis-TAS1303260  
GO:0030522intracellular receptor signaling pathway-IEA-  
GO:0043066negative regulation of apoptotic process-TAS12531696  
GO:0045967negative regulation of growth rate-IDA11306509  
GO:0046579positive regulation of Ras protein signal transduction-IDA11306509  
GO:0046849bone remodeling-IMP21378985  21378989  
GO:0060413atrial septum morphogenesis-IMP16773578  
GO:0061314Notch signaling involved in heart development-IC16773578  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IDA11306509  
GO:2001204regulation of osteoclast development-IMP29149593  
GO ID GO Term Qualifier Evidence PubMed
GO:0000139Golgi membrane-TAS-  
GO:0005576extracellular region-TAS-  
GO:0005634nucleus-IDA1303260  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005789endoplasmic reticulum membrane-TAS-  
GO:0005886plasma membrane-IDA-  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-IDA9244302  
GO:0009986cell surface-IDA9244302  
GO:0016020membrane-HDA19946888  
GO:0043235receptor complex-IDA23382219  
KEGG ID KEGG Term
hsa04320Dorso-ventral axis formation
hsa04330Notch signaling pathway
Reactome ID Reactome Term Evidence
R-HSA-157118Signaling by NOTCHTAS
R-HSA-157118Signaling by NOTCHIEA
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-1643685DiseaseTAS
R-HSA-1912399Pre-NOTCH Processing in the Endoplasmic ReticulumIEA
R-HSA-1912408Pre-NOTCH Transcription and TranslationTAS
R-HSA-1912420Pre-NOTCH Processing in GolgiTAS
R-HSA-1912420Pre-NOTCH Processing in GolgiIEA
R-HSA-1912422Pre-NOTCH Expression and ProcessingTAS
R-HSA-1912422Pre-NOTCH Expression and ProcessingIEA
R-HSA-1980145Signaling by NOTCH2IEA
R-HSA-1980145Signaling by NOTCH2TAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2197563NOTCH2 intracellular domain regulates transcriptionTAS
R-HSA-2197563NOTCH2 intracellular domain regulates transcriptionIEA
R-HSA-2979096NOTCH2 Activation and Transmission of Signal to the NucleusIEA
R-HSA-2979096NOTCH2 Activation and Transmission of Signal to the NucleusTAS
R-HSA-350054Notch-HLH transcription pathwayTAS
R-HSA-3781865Diseases of glycosylationTAS
R-HSA-3906995Diseases associated with O-glycosylation of proteinsTAS
R-HSA-5083630Defective LFNG causes SCDO3TAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28559012Establishment and characterization of an oral tongue squamous cell carcinoma cell line from a never-smoking patient. (2017 Jun)Wang SJOral Oncol
29032150Functional analysis of schizophrenia genes using GeneAnalytics program and integrated databases. (2018 Jan 30)Sundararajan TGene
28061457Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer. (2017 Feb 21)Xiong JOncotarget
28737528Genetic variants of increased waist circumference in psychosis. (2017 Dec)Hukic DSPsychiatr Genet
25962154Downregulation of notch signaling pathway in late preterm and term placentas from pregnancies complicated by preeclampsia. (2015)Fragkiadaki PPLoS One
19020324Clinical risk factors, DNA variants, and the development of type 2 diabetes. (2008 Nov 20)Lyssenko VN Engl J Med
22975805The transcriptional landscape and mutational profile of lung adenocarcinoma. (2012 Nov)Seo JSGenome Res
19106307Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. (2009 Mar 15)Tilley AEAm J Respir Crit Care Med
21791674Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium. (2011 Aug 17)Campa DJ Natl Cancer Inst